tal1 (SPCC1020.06c)


Gene Standard Nametal1 Characterisation Statusbiological_role_inferred
Systematic IDSPCC1020.06c Feature Typeprotein coding
Synonyms Name Description
Producttransaldolase (predicted) Product Size322aa, 35.24 kDa
Genomic Location Chromosome III, 773329-774834 (1506nt); CDS:773498-774466 (969nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
Term NameCount
pentose-phosphate shunt, non-oxidative branch4
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytoplasm4206
Annotation ExtensionEvidenceWith/FromReference
cytosol2316
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationtal1ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphology3092
penetrance FYPO_EXT:0000001tal1ΔNull
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1773329773410
2773488774834

UTRs

Region Coordinates Reference
five_prime_UTR773329..773410,773488..773497PMID:21511999
three_prime_UTR774467..774834PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00923 Pfam IPR001585 Transaldolase 14 313 1
PS00958 Prosite Patterns IPR018225 Transaldolase, active site 129 146 1
PS01054 Prosite Patterns IPR018225 Transaldolase, active site 31 39 1
PTHR10683 HMMPANTHER IPR001585 Transaldolase 1 321 1
PTHR10683:SF6 HMMPANTHER 1 321 1
3.20.20.70 Gene3D IPR013785 Aldolase-type TIM barrel 1 319 35
SSF51569 SuperFamily 1 320 9
MF_00492 hamap IPR004730 Transaldolase type 1 1 320 1
TIGR00874 tigrfam IPR004730 Transaldolase type 1 3 320 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.44 Da
Charge -2.00
Isoelectric point 5.54
Molecular weight 35.24 kDa
Number of residues 322
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1670
present during cellular response to thiabendazoleS225
present during cellular response to thiabendazoleS68
present during cellular response to thiabendazoleS269
Annotation ExtensionEvidenceResidueReference
present during cellular response to thiabendazole IDA S68 PMID:18257517
present during cellular response to thiabendazole IDA S225 PMID:18257517
present during cellular response to thiabendazole IDA S269 PMID:18257517
phosphorylated residue 1922
Annotation ExtensionEvidenceResidueReference
NAS PMID:18257517
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
766740during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
800152during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
732986during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
840616during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
747526during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
150632.97during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
70615.78during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
62during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
6.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in bacteria1000
conserved in metazoa3432
conserved in vertebrates3407
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
cwf2RNA-binding protein Cwf2 Affinity Capture-MSPMID:21386897
crp79poly(A) binding protein Crp79 Affinity Capture-RNAPMID:20531409
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
paa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:22119525
far8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
ppk16serine/threonine protein kinase Ppk16 (predicted) Positive GeneticPMID:22681890
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
vps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Positive GeneticPMID:22681890
pyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Positive GeneticPMID:22681890
srp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Positive GeneticPMID:22681890
plb1phospholipase B homolog Plb1 Negative GeneticPMID:22681890
dbr1RNA lariat debranching enzyme Dbr1 Positive GeneticPMID:22681890
cut1separase/separin Negative GeneticPMID:22681890
rcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Positive GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Positive GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
SPAC1B3.02ctranscription elongation factor, Elf1 family (predicted) Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Positive GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
dsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
fml2ATP-dependent 3' to 5' DNA helicase (predicted) Negative GeneticPMID:22681890
psl1cyclin pho85 family Psl1 (predicted) Negative GeneticPMID:22681890
csn1COP9/signalosome complex subunit Csn1 Positive GeneticPMID:22681890
res2MBF transcription factor complex subunit Res2 Positive GeneticPMID:22681890
dsc5UBX domain containing protein required for Sre1 cleavage Negative GeneticPMID:22681890
air1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:22681890
int6eIF3e subunit Int6 Negative GeneticPMID:22681890
ppm1leucine carboxyl methyltransferase Ppm1 (predicted) Negative GeneticPMID:22681890
tps1alpha,alpha-trehalose-phosphate synthase Positive GeneticPMID:22681890
lsc1Lsk1 associated cyclin Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC1020.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1020.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1020.06c BioGRID Interaction Datasets
Expression Viewer SPCC1020.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1020.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1020.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1020.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1020.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1020.06c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1020.06c Cell Cycle Data
GEO SPCC1020.06c GEO profiles
PInt SPCC1020.06c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1020.06c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1020.06c Fission yeast phenotypic data & analysis
IntEnz2.2.1.2Integrated relational Enzyme database
Rhea2.2.1.2Annotated reactions database
SPD / RIKEN13/13G10Orfeome Localization Data
UniProtKB/SwissProtO42700Transaldolase
ModBaseO42700Database of comparative protein structure models
STRINGO42700Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587953transaldolase (predicted)
RefSeq mRNANM_001022944972h- transaldolase (predicted) (tal1), mRNA
European Nucleotide ArchiveAB010049ENA EMBL mapping
European Nucleotide ArchiveCAA18994.1ENA Protein Mapping
MetaCycPWY-1861Formaldehyde assimilation II (RuMP Cycle)
MetaCycPWY-5723Rubisco shunt
KEGG_Enzyme00030+2.2.1.2Pentose phosphate pathway
UniParcUPI0000136886UniProt Archive
UniPathwayUPA00115Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3

Literature for tal1

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015