SPCC1183.02


Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPCC1183.02 Feature Typeprotein coding
Synonyms Name Description
Productglutathione S-transferase (predicted) Product Size220aa, 25.50 kDa
Genomic Location Chromosome III, 594963-596054 (1092nt); CDS:595060-596002 (943nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
glutathione transferase activity8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2315
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationSPCC1183.02ΔNull3792

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologySPCC1183.02ΔNull3092
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons594963..595212, 595493..596054
mRNA594963..596054
5' UTR594963..595059PMID:21511999
CDS595060..595212, 595493..596002
3' UTR596003..596054AU013839
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00043 Pfam IPR004046 Glutathione S-transferase, C-terminal 125 200 6
PF13417 Pfam IPR004045 Glutathione S-transferase, N-terminal 17 76 1
PS50404 Prosite Profiles IPR004045 Glutathione S-transferase, N-terminal 2 81 5
PS50405 Prosite Profiles IPR010987 Glutathione S-transferase, C-terminal-like 89 216 7
PTHR11260:SF143 HMMPANTHER 1 207 3
PTHR11260 HMMPANTHER 1 207 6
3.40.30.10 Gene3D IPR012336 Thioredoxin-like fold 1 79 36
1.20.1050.10 Gene3D IPR010987 Glutathione S-transferase, C-terminal-like 82 208 11
SSF52833 SuperFamily IPR012336 Thioredoxin-like fold 1 76 38
SSF47616 SuperFamily IPR010987 Glutathione S-transferase, C-terminal-like 80 208 12

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000261thioredoxin familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000261

Protein Properties

Ave. residue weight 115.93 Da
Charge 1.00
Isoelectric point 6.95
Molecular weight 25.50 kDa
Number of residues 220
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
364335during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
375194during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
349326during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
357052during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
42479.74during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
355634during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
14170.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6.6during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
faster evolving duplicate23
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byhhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
affinity captured bypaa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:22119525
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
External References
Database Identifier Description
NBRP SPCC1183.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1183.02 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1183.02 BioGRID Interaction Datasets
Expression Viewer SPCC1183.02 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1183.02 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1183.02 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1183.02 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1183.02 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1183.02 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1183.02 Cell Cycle Data
GEO SPCC1183.02 GEO profiles
PInt SPCC1183.02 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1183.02 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1183.02 Fission yeast phenotypic data & analysis
SPD / RIKEN13/13C03Orfeome Localization Data
UniProtKB/SwissProtO74830Putative glutathione S-transferase C1183.02
ModBaseO74830Database of comparative protein structure models
STRINGO74830Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587885glutathione S-transferase (predicted)
RefSeq mRNANM_001022877972h- glutathione S-transferase (predicted) (SPCC1183.02), mRNA
European Nucleotide ArchiveCAA21082.1ENA Protein Mapping
UniParcUPI000006A908UniProt Archive

Literature for SPCC1183.02

Search: Europe PMC or PubMed

Release Version: PomBase:25_50 - 10 Mar 2015