SPCC1183.02


Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPCC1183.02 Feature Typeprotein coding
Synonyms Name Description
Productglutathione S-transferase (predicted) Product Size220aa, 25.50 kDa
Genomic Location Chromosome III, 594963-596054 (1092nt); CDS:595060-596002 (943nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004364glutathione transferase activityIEA EC:2.5.1.18GO_REF:00000038
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051193
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPCC1183.02ΔNullPMID:204732893760
MicroscopySPCC1183.02ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001MicroscopySPCC1183.02ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1594963595212
2595493596054

UTRs

Region Coordinates Reference
five_prime_UTR594963..595059PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF13417 Pfam IPR004045 Glutathione S-transferase, N-terminal 17 76 1
PF00043 Pfam IPR004046 Glutathione S-transferase, C-terminal 125 200 6
PS50404 Prosite Profiles IPR004045 Glutathione S-transferase, N-terminal 2 81 5
PS50405 Prosite Profiles IPR010987 Glutathione S-transferase, C-terminal-like 89 216 7
PTHR11260:SF143 HMMPANTHER 1 207 3
PTHR11260 HMMPANTHER 1 207 6
1.20.1050.10 Gene3D IPR010987 Glutathione S-transferase, C-terminal-like 82 208 10
3.40.30.10 Gene3D IPR012336 Thioredoxin-like fold 1 79 36
SSF52833 SuperFamily IPR012336 Thioredoxin-like fold 1 76 38
SSF47616 SuperFamily IPR010987 Glutathione S-transferase, C-terminal-like 80 208 12

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000261thioredoxin familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000261

Protein Properties

Ave. residue weight 115.93 Da
Charge 1.00
Isoelectric point 6.95
Molecular weight 25.50 kDa
Number of residues 220
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
42479.74during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
355634during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
375194during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
364335during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
349326during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
357052during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
14170.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
6.6during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
faster evolving duplicate23
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
paa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:22119525
External References
Database Identifier Description
NBRP SPCC1183.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1183.02 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1183.02 BioGRID Interaction Datasets
Expression Viewer SPCC1183.02 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1183.02 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1183.02 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1183.02 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1183.02 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1183.02 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1183.02 Cell Cycle Data
GEO SPCC1183.02 GEO profiles
PInt SPCC1183.02 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene2539015glutathione S-transferase (predicted)
WikiGene2539015glutathione S-transferase (predicted)
SPD / RIKEN13/13C03Orfeome Localization Data
UniProtKB/SwissProtO74830Putative glutathione S-transferase C1183.02
ModBaseO74830Database of comparative protein structure models
STRINGO74830Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587885glutathione S-transferase (predicted)
RefSeq mRNANM_001022877972h- glutathione S-transferase (predicted) (SPCC1183.02), mRNA
European Nucleotide ArchiveCAA21082ENA Protein Mapping
European Nucleotide ArchiveCAA21082.1ENA Protein Mapping
UniParcUPI000006A908UniProt Archive

Literature for SPCC1183.02

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014