rpl101 (SPCC1183.08c)

Gene Standard Namerpl101 Characterisation Statuspublished
Systematic IDSPCC1183.08c Feature Typeprotein coding
Synonymsrpl1-1, rpl10a-1 Name Description
Product60S ribosomal protein L10a Product Size216aa, 23.92 kDa
Genomic Location Chromosome III, 612630-611797 (834nt); CDS:612550-611900 (651nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome256
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation471
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit82
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationrpl101Δ1468

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination with normal, unseptated germ tube morphologyrpl101Δ237
inviable sporerpl101Δ476
Target Of
GO substrate of ubp15 ubiquitin C-terminal hydrolase Ubp15
GO substrate of ubp4 ubiquitin C-terminal hydrolase Ubp4
GO substrate of ubp5 ubiquitin C-terminal hydrolase Ubp5
GO substrate of ubp9 ubiquitin C-terminal hydrolase Ubp9
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR612630..612551PMID:21511999
3' UTR611899..611797PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 22 210 5
PS01199 Prosite Patterns IPR023673 Ribosomal protein L1, conserved site 116 135 2
PTHR23105:SF54 HMMPANTHER 1 216 2
PTHR23105 HMMPANTHER 1 216 8 Gene3D IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich 62 151 4 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 152 216 5 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 8 60 5
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 3 216 5
PIRSF002155 PIRSF IPR002143 Ribosomal protein L1 1 216 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.73 Da
Charge 18.50
Codon Adaptation Index 0.80
Isoelectric point 10.52
Molecular weight 23.92 kDa
Number of residues 216

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 2293
present during mitotic M phaseS11
S8, S11
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S11 PMID:21712547
experimental evidence S8 PMID:24763107
IDA S11 PMID:25720772
IDA S8 PMID:25720772
ubiquitinylated lysineK77 514
Annotation ExtensionEvidenceResidueReference
mass spectrometry evidence K77 PMID:26412298
IDA PMID:26412298
sumoylated lysine 174
Annotation ExtensionEvidenceResidueReference
IDA PMID:26404184
O-phosphorylated residueS5,S11, S8,S11 2461
Annotation ExtensionEvidenceResidueReference
IDA S8,S11 PMID:25720772
IDA S5,S11 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rpl101 (SPCC1183.08c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
128923during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
120195during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
127354during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
141473during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
200647.84during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
127341during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
10938.71during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
90during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
7.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
conserved in fungi4608
conserved in eukaryotes4516
conserved in bacteria1005
conserved in metazoa3498
conserved in vertebrates3473

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPCC1183.08c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byimp1importin alpha Affinity Capture-MSPMID:25963819
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
affinity captured bycid14TRAMP complex poly(A) polymerase subunit Cid14 Affinity Capture-MSPMID:20403971
binds activation domain construct withrpl10160S ribosomal protein L10a Two-hybridPMID:26771498
External References
Database Identifier Description
NBRP SPCC1183.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1183.08c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1183.08c BioGRID Interaction Datasets
Expression Viewer SPCC1183.08c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1183.08c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1183.08c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1183.08c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1183.08c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1183.08c Transcriptome Viewer (Bähler Lab)
GEO SPCC1183.08c GEO profiles
PInt SPCC1183.08c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1183.08c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1183.08c Fission yeast phenotypic data & analysis
Cyclebase SPCC1183.08c.1 Cell Cycle Data
SPD / RIKEN42/42F10Orfeome Localization Data
UniProtKB/SwissProtO7483660S ribosomal protein L1-B
ModBaseO74836Database of comparative protein structure models
STRINGO74836Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_58789160S ribosomal protein L1
RefSeq mRNANM_001022883972h- 60S ribosomal protein L1 (rpl101), mRNA
European Nucleotide ArchiveCAA21088.1ENA Protein Mapping
UniParcUPI0000132EB8UniProt Archive

Literature for rpl101

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017