spo13 (SPCC1183.12)


Gene Standard Namespo13 Characterisation Statuspublished
Systematic IDSPCC1183.12 Feature Typeprotein coding
SynonymsSPNCRNA.546, SPNGAF60 Name Description
Productsporulation specific guanyl-nucleotide exchange factor Spo13 Product Size138aa, 15.86 kDa
Genomic Location Chromosome III, 604961-604366 (596nt); CDS:604872-604405 (468nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005085guanyl-nucleotide exchange factor activity36
heterologous_systemIGISGD:S000005216PMID:20130084
GO:0005515protein bindingIPIspo2PMID:18367542861
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030437ascospore formationIMPPMID:344282487
IMPPMID:8203159
IMPPMID:18367542
GO:0032120ascospore-type prospore membrane assemblyIMPPMID:201300847
GO:0031322ascospore-type prospore-specific spindle pole body remodelingIMPPMID:183675427
GO:0043547positive regulation of GTPase activityIGISGD:S000005216PMID:2013008452
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0035974meiotic spindle pole body12
during meiotic cell cycleIDAPMID:18367542
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationnot recorded (unrecorded)PMID:183675423760

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0003138abnormal ascospore wall morphologyMicroscopyspo13Not specifiedPMID:82031595
FYPO:0002711abnormal nuclear separation after meiosisMicroscopyspo13Not specifiedPMID:82031594
FYPO:0000121abnormal sporulationnot recorded (unrecorded)PMID:18367542111
FYPO:0000585abolished ascospore wall biogenesisMicroscopyspo13Not specifiedPMID:14174175
FYPO:0000583abolished sporulationMicroscopyspo13Not specifiedPMID:141741729
Microscopyspo13-B82Not specifiedPMID:3442824
FYPO:0000478normal meiosisMicroscopyspo13-B82Not specifiedPMID:3442824123
FYPO:0003137normal mitotic spindle pole bodyMicroscopyspo13Not specifiedPMID:82031599
FYPO:0002710spindle pole body absent from cell after meiosis IIMicroscopyspo13Not specifiedPMID:82031599
Target Of
OntologyRelationshipGeneProductReference
GO localized by spo15 sporulation protein Spo15 PMID:18367542
GO localized by spo2 sporulation specific protein Spo2 PMID:18367542
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1604961604857
2604805604366

UTRs

Region Coordinates Reference
five_prime_UTR604961..604873PMID:21511999
three_prime_UTR604404..604366PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06428 Pfam IPR009449 GDPGTP exchange factor Sec2p 47 119 2
PTHR14430 HMMPANTHER 41 120 2
0053574 SuperFamily 38 120 2
Coil ncoils Rabaptin coiled-coil domain 41 76 968
Coil ncoils Rabaptin coiled-coil domain 84 105 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.94 Da
Charge 2.00
Isoelectric point 8.91
Molecular weight 15.86 kDa
Number of residues 138
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelexclusively during GO:0007127experimental evidencePMID:1836754

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
NDduring GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.15during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.31during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
previously annotated as ncRNA21
Species Distribution
DescriptionQualifierReferenceCount
orthologs cannot be distinguished132
Orthologs

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
spo7sporulation protein Spo7 Two-hybridPMID:21775631
External References
Database Identifier Description
NBRP SPCC1183.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1183.12 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1183.12 BioGRID Interaction Datasets
Expression Viewer SPCC1183.12 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1183.12 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1183.12 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1183.12 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1183.12 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1183.12 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1183.12 Cell Cycle Data
GEO SPCC1183.12 GEO profiles
PInt SPCC1183.12 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene9407039sporulation specific protein Spo13
EntrezGene9407039sporulation specific protein Spo13
UniProtKB/SwissProtC6Y4C9Sporulation-specific protein 13
ModBaseC6Y4C9Database of comparative protein structure models
STRINGC6Y4C9Network display of known and predicted interactions and functional associations
RefSeq mRNAXM_002788902972h- sporulation specific protein Spo13 (spo13), mRNA
RefSeq PeptideXP_002788948sporulation specific protein Spo13
European Nucleotide ArchiveCBA11516ENA Protein Mapping
European Nucleotide ArchiveCBA11516.1ENA Protein Mapping
UniParcUPI0001B0625AUniProt Archive

Literature for spo13

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014