spo13 (SPCC1183.12)

Gene Standard Namespo13 Characterisation Statuspublished
Systematic IDSPCC1183.12 Feature Typeprotein coding
SynonymsSPNCRNA.546, SPNGAF60 Name Description
Productsporulation specific guanyl-nucleotide exchange factor Spo13 Product Size138aa, 15.86 kDa
Genomic Location Chromosome III, 604961-604366 (596nt); CDS:604872-604405 (468nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
guanyl-nucleotide exchange factor activity33
Annotation ExtensionEvidenceWith/FromReference
protein binding859
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
ascospore formation63
Annotation ExtensionEvidenceWith/FromReference
ascospore-type prospore membrane assembly11
Annotation ExtensionEvidenceWith/FromReference
ascospore-type prospore-specific spindle pole body remodeling9
Annotation ExtensionEvidenceWith/FromReference
positive regulation of GTPase activity69
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
meiotic spindle pole body17
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationunnamed (unrecorded)3809

Cell Phenotype

Term NameAlleleExpressionCount
abnormal sporulationunnamed (unrecorded)208
abolished ascospore wall biogenesisspo13Not specified5
abolished sporulationspo13Not specified54
spo13-B82Not specified
normal meiosisspo13-B82Not specified144
Target Of
GO localized by spo15 sporulation protein Spo15
GO localized by spo2 sporulation specific protein Spo2
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons604961..604857, 604805..604366
5' UTR604961..604873PMID:21511999
CDS604872..604857, 604805..604405
3' UTR604404..604366PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06428 Pfam IPR009449 GDPGTP exchange factor Sec2p 47 119 2
PTHR14430 HMMPANTHER 41 120 2
0053574 SuperFamily 38 120 2
Coil ncoils Rabaptin coiled-coil domain 41 76 968
Coil ncoils Rabaptin coiled-coil domain 84 105 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.94 Da
Charge 2.00
Isoelectric point 8.91
Molecular weight 15.86 kDa
Number of residues 138
Gene Expression

Qualitative Gene Expression

RNA levelexclusively during GO:0007127experimental evidencePMID:1836754

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.15during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
0.31during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
previously annotated as ncRNA21
Species Distribution
orthologs cannot be distinguished129

Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds DNA-binding domain construct withspo7sporulation protein Spo7 Two-hybridPMID:21775631
External References
Database Identifier Description
NBRP SPCC1183.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1183.12 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1183.12 BioGRID Interaction Datasets
Expression Viewer SPCC1183.12 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1183.12 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1183.12 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1183.12 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1183.12 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1183.12 Transcriptome Viewer (Bähler Lab)
GEO SPCC1183.12 GEO profiles
PInt SPCC1183.12 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1183.12 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1183.12 Fission yeast phenotypic data & analysis
Cyclebase SPCC1183.12.1 Cell Cycle Data
UniProtKB/SwissProtC6Y4C9Sporulation-specific protein 13
ModBaseC6Y4C9Database of comparative protein structure models
STRINGC6Y4C9Network display of known and predicted interactions and functional associations
RefSeq mRNAXM_002788902972h- sporulation specific protein Spo13 (spo13), mRNA
RefSeq PeptideXP_002788948sporulation specific protein Spo13
European Nucleotide ArchiveCBA11516.1ENA Protein Mapping
UniParcUPI0001B0625AUniProt Archive

Literature for spo13

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015