spo13 (SPCC1183.12)

Gene Standard Namespo13 Characterisation Statuspublished
Systematic IDSPCC1183.12 Feature Typeprotein coding
SynonymsSPNCRNA.546, SPNGAF60 Name Description
Productsporulation specific guanyl-nucleotide exchange factor Spo13 Product Size138aa, 15.86 kDa
Genomic Location Chromosome III, 604961-604366 (596nt); CDS:604872-604405 (468nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005085guanyl-nucleotide exchange factor activity36
GO:0005515protein bindingIPIspo2PMID:18367542887
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030437ascospore formationIMPPMID:1836754299
GO:0032120ascospore-type prospore membrane assemblyIMPPMID:201300847
GO:0031322ascospore-type prospore-specific spindle pole body remodelingIMPPMID:183675427
GO:0043087regulation of GTPase activityIGISGD:S000005216PMID:2013008474
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0035974meiotic spindle pole body12
during meiotic cell cycleIDAPMID:18367542
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationno_namePMID:183675423755

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000121abnormal sporulationno_namePMID:18367542110
FYPO:0000585abolished ascospore wall biogenesisMicroscopyspo13Not specifiedPMID:14174175
FYPO:0000583abolished sporulationMicroscopyspo13-B82Not specifiedPMID:344282425
Microscopyspo13Not specifiedPMID:1417417
FYPO:0000478normal meiosisMicroscopyspo13-B82Not specifiedPMID:344282412
Target Of
localized by spo15 sporulation protein Spo15 PMID:18367542
localized by spo2 sporulation specific protein Spo2 PMID:18367542
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06428 Pfam IPR009449 GDPGTP exchange factor Sec2p 47 119 2
SSF144284 SuperFamily 38 120 2
Coil ncoils Rabaptin coiled-coil domain 41 76 975
Coil ncoils Rabaptin coiled-coil domain 84 105 975
Low complexity (SEG) seg 50 68
Low complexity (SEG) seg 12 23

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.94 Da
Charge 2.00
Isoelectric point 8.91
Molecular weight 15.86 kDa
Number of residues 138
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
NDduring GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.15during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.31during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
previously annotated as ncRNA21
Species Distribution
orthologs cannot be distinguished132

Orthologs in Compara

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
spo7sporulation protein Spo7 Two-hybridPMID:21775631
External References
Database Identifier Description
NBRP SPCC1183.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1183.12 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1183.12 BioGRID Interaction Datasets
Expression Viewer SPCC1183.12 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1183.12 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1183.12 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1183.12 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1183.12 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1183.12 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1183.12 Cell Cycle Data
GEO SPCC1183.12 GEO profiles
PInt SPCC1183.12 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene9407039sporulation specific protein Spo13
EntrezGene9407039sporulation specific protein Spo13
UniProtKB/SwissProtC6Y4C9Sporulation-specific protein 13
ModBaseC6Y4C9Database of comparative protein structure models
StringC6Y4C9Network display of known and predicted interactions and functional associations
RefSeq_mRNA_predictedXM_002788902972h- sporulation specific protein Spo13 (spo13), mRNA
RefSeq_peptide_predictedXP_002788948sporulation specific protein Spo13
European Nucleotide ArchiveCBA11516ENA Protein Mapping
UniParcUPI0001B0625AUniProt Archive

Literature for spo13

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014