rik1 (SPCC11E10.08)


Gene Standard Namerik1 Characterisation Statuspublished
Systematic IDSPCC11E10.08 Feature Typeprotein coding
Synonyms Name Description
Productsilencing protein Rik1 Product Size1040aa, 118.12 kDa
Genomic Location Chromosome III, 1467695-1471912 (4218nt); CDS:1468174-1471296 (3123nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003677DNA bindingISSddb1GO_REF:0000001385
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0034613cellular protein localization552
localizes swi6IMPPMID:8937892
localizes clr4IMPPMID:10766735
localizes clr4IMPPMID:15197176
GO:0030702chromatin silencing at centromereIMPPMID:785179553
GO:0030466chromatin silencing at silent mating-type cassette32
requiredIMPPMID:8138176
GO:0006348chromatin silencing at telomereTASPMID:1519717622
GO:0007535donor selectionIMPPMID:151971764
GO:0030989dynein-driven meiotic oscillatory nuclear movementIGIclr4PMID:1519717613
GO:0035391maintenance of chromatin silencing at silent mating-type cassetteNASGO_REF:00000013
GO:0045141meiotic telomere clusteringIMPPMID:1519717614
GO:0051572negative regulation of histone H3-K4 methylationIMPPMID:160246595
GO:0051574positive regulation of histone H3-K9 methylationIMPPMID:107667354
NOT GO:0000723telomere maintenanceIMPPMID:15197176
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0043494CLRC ubiquitin ligase complexIDAPMID:160246597
GO:0044732mitotic spindle pole bodyIDAPMID:16823372214
GO:0000790nuclear chromatinTASPMID:15372076279
GO:0005634nucleusIDAPMID:168233722740
GO:0043234protein complexEXPPMID:217253251361
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001701sensitive to bortezomib256
expressivity FYPO_EXT:0000001Cell growth assayrik1ΔNullPECO:0000005, PECO:0000137PMID:21760946
FYPO:0000096sensitive to cadmium246
expressivity FYPO_EXT:0000003Cell growth assayrik1ΔNullPECO:0000102, PECO:0000005, PECO:0000137PMID:18684775
FYPO:0000271sensitive to salt stress82
expressivity FYPO_EXT:0000003Cell growth assayrik1ΔNullPECO:0000207, PECO:0000137, PECO:0000102, PECO:0000005PMID:18684775
FYPO:0000091sensitive to thiabendazolecompetitive growth assay evidencerik1ΔNullPMID:20537132168
FYPO:0002060viable vegetative cell populationMicroscopyrik1ΔNullPECO:0000005, PECO:0000137PMID:236978063730
Microscopyrik1ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrik1ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
114676951471912

UTRs

Region Coordinates Reference
three_prime_UTR1471297..1471912PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03178 Pfam IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminal 712 1000 5
PTHR10644 HMMPANTHER 1 1040 4
PTHR10644:SF3 HMMPANTHER 1 1040 2
Coil ncoils Rabaptin coiled-coil domain 695 716 968
Coil ncoils Rabaptin coiled-coil domain 953 974 968

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190
PBO:0001290rik1/ddb1 subfamilyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001290

Protein Properties

Ave. residue weight 113.58 Da
Charge 0.50
Isoelectric point 6.55
Molecular weight 118.12 kDa
Number of residues 1040
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
377during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
362during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
326during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
NDduring GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.5during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.46during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog579
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
med20mediator complex subunit Med20 Positive GeneticPMID:18818364
pnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:18818364
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
pph3serine/threonine protein phosphatase, PP4 complex subunit Pph3 (predicted) Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
pmc1mediator complex subunit Pmc1 Negative GeneticPMID:18818364
mph1dual specificity protein kinase Mph1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
SPAC513.07flavonol reductase/cinnamoyl-CoA reductase family Positive GeneticPMID:22681890
nse5Smc5-6 complex non-SMC subunit Nse5 Synthetic Growth DefectPMID:18931302
rpl430260S ribosomal protein L37a (predicted) Negative GeneticPMID:22681890
elp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
mms19Dos2 silencing complex subunit Mms19 Positive GeneticPMID:18818364
msh6MutS protein homolog Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
bub3mitotic spindle checkpoint protein Bub3 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
spc34DASH complex subunit Spc34 Negative GeneticPMID:18818364
mpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 (predicted) Negative GeneticPMID:22681890
fta6Sim4 and Mal2 associated (4 and 2 associated) protein 6 Positive GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
elp3elongator complex subunit Elp3 (predicted) Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
gar2nucleolar protein required for rRNA processing Negative GeneticPMID:22681890
SPAC24B11.05pyrimidine 5'-nucleotidase (predicted) Negative GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Positive GeneticPMID:22681890
SPAC521.03short chain dehydrogenase (predicted) Negative GeneticPMID:22681890
pac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
bag101BAG family molecular chaperone regulator Bag101 (predicted) Positive GeneticPMID:24497846
csk1cyclin-dependent kinase activating kinase Csk1 Negative GeneticPMID:22681890
tea2kinesin-like protein Tea2 Negative GeneticPMID:18818364
snf5SWI/SNF complex subunit Snf5 Positive GeneticPMID:22681890
cwf19complexed with Cdc5 protein Cwf19 Negative GeneticPMID:22681890
pmk1MAP kinase Pmk1 Positive GeneticPMID:22681890
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
dbl5ubiquitin-protein ligase E3 Dbl5 Positive GeneticPMID:22681890
pas4peroxisomal ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
rap1telomere binding protein Rap1 Positive GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
sgo1inner centromere protein, shugoshin, Sgo1 Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
pmc5mediator complex subunit Pmc5 Positive GeneticPMID:18818364
SPAC1071.05S-adenosylmethionine-dependent methyltransferase (predicted) Positive GeneticPMID:22681890
pzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
swc5Swr1 complex subunit Swc5 Negative GeneticPMID:18818364
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
tas3RITS complex subunit 3 Positive GeneticPMID:18818364
Phenotypic EnhancementPMID:21060862
Synthetic Growth DefectPMID:20705239
rpb9DNA-directed RNA polymerase II complex subunit Rpb9 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
psl1cyclin pho85 family Psl1 (predicted) Positive GeneticPMID:22681890
vht1vitamin H transporter Vht1 Positive GeneticPMID:22681890
SPBP16F5.05cribosome biogenesis protein Nop8 (predicted) Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
atb2tubulin alpha 2 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
zip1transcription factor Zip1 Negative GeneticPMID:22681890
ers1RNA-silencing factor Ers1 Positive GeneticPMID:18818364
SPAC750.08cNAD-dependent malic enzyme (predicted), partial Positive GeneticPMID:22681890
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
SPBP8B7.18cphosphomethylpyrimidine kinase (predicted) Positive GeneticPMID:18818364
rad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:18818364
rpl170260S ribosomal protein L17 (predicted) Negative GeneticPMID:22681890
SPBC16G5.03ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
pca1metacaspase Pca1 Negative GeneticPMID:22681890
nup61nucleoporin Nup61 Negative GeneticPMID:18818364
rps00140S ribosomal protein S0A (p40) Negative GeneticPMID:22681890
lsc1Lsk1 associated cyclin Negative GeneticPMID:22681890
clr3histone deacetylase (class II) Clr3 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
erf2palmitoyltransferase Erf2 Positive GeneticPMID:22681890
gsk3serine/threonine protein kinase Gsk3 Positive GeneticPMID:22681890
tlg2SNARE Tlg2 (predicted) Synthetic Growth DefectPMID:18931302
sum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
msy1MS calcium ion channel protein Msy1 Negative GeneticPMID:22681890
ago1argonaute Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
Synthetic Growth DefectPMID:20705239
Dosage Rescue
hhf2histone H4 h4.2 Positive GeneticPMID:22681890
mad2spindle checkpoint protein Mad2 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
ura3dihydroorotate dehydrogenase Ura3 Negative GeneticPMID:22681890
mis6inner centromere protein, CENP-I ortholog Mis6 Synthetic Growth DefectPMID:12719471
fml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Negative GeneticPMID:18818364
spf38U5 snRNP complex subunit Spf38 Negative GeneticPMID:22681890
ath1ataxin-2 homolog Negative GeneticPMID:22681890
isu1mitochondrial iron-sulfur cluster assembly scaffold protein Isu1 Negative GeneticPMID:22681890
mal3EB1 family Mal3 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
los1karyopherin exportin T Los1 (predicted) Positive GeneticPMID:22681890
SPCC16C4.20cHMG box protein (predicted) Negative GeneticPMID:22681890
mre11Mre11 nuclease Negative GeneticPMID:18818364
SPAC18G6.13sequence orphan Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
btf3nascent polypeptide-associated complex beta subunit Negative GeneticPMID:22681890
elp1elongator subunit Elp1 (predicted) Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
gmh5alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
rad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Negative GeneticPMID:22681890
arb1argonaute inhibitor protein 1 Positive GeneticPMID:22681890
tma20RNA-binding protein Tma20 (predicted) Positive GeneticPMID:22681890
pds5cohesin-associated protein Pds5 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
elp6elongator complex subunit Elp6 (predicted) Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
mgr2mitochondrial membrane protein Mgr2 (predicted) Negative GeneticPMID:22681890
mug80cyclin Clg1 (predicted) Positive GeneticPMID:22681890
asp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Negative GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
nup124nucleoporin Nup124 Negative GeneticPMID:22681890
SPAC6G9.14RNA-binding protein (predicted) Negative GeneticPMID:22681890
dcc1Ctf18 RFC-like complex subunit Dcc1 Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
clp1Cdc14-related protein phosphatase Clp1/Flp1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
imp1importin alpha Negative GeneticPMID:22681890
psy2protein phosphatase PP4 complex subunit Psy2 (predicted) Negative GeneticPMID:22681890
ryh1GTPase Ryh1 Negative GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Negative GeneticPMID:22681890
nop16ribosome biogenesis protein Nop16 (predicted) Negative GeneticPMID:22681890
msd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
SPBC1861.05pseudouridine-metabolizing bifunctional protein (predicted) Positive GeneticPMID:22681890
pht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:18818364
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
med13mediator complex subunit Srb9 Negative GeneticPMID:18818364
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
rps80140S ribosomal protein S8 (predicted) Negative GeneticPMID:22681890
ser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
ark1aurora-B kinase Ark1 Negative GeneticPMID:22681890
SPAC17H9.13cglutamate 5-kinase (predicted) Negative GeneticPMID:22681890
srb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:22681890
rev7DNA polymerase zeta Rev7 (predicted) Negative GeneticPMID:18818364
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
SPAC10F6.08cHMG box protein Negative GeneticPMID:22681890
rdp1RNA-directed RNA polymerase Rdp1 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
Synthetic Growth DefectPMID:20705239
fhl1forkhead transcription factor Fhl1 Synthetic Growth DefectPMID:18931302
plr1pyridoxal reductase Plr1 Positive GeneticPMID:22681890
rpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
ase1antiparallel microtubule cross-linking factor Ase1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
sce3translation initiation factor (predicted) Positive GeneticPMID:22681890
rds1conserved fungal protein Positive GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
scm3CENP-A chaperone Scm3 Synthetic Growth DefectPMID:12719471
clr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:18818364
Phenotypic SuppressionPMID:20211136
Positive GeneticPMID:22681890
Dosage RescuePMID:20705239
SPCC594.04csteroid oxidoreductase superfamily protein (predicted) Negative GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
nup132nucleoporin Nup132 Positive GeneticPMID:22681890
ctu1cytosolic thiouridylase subunit Ctu1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
SPAC222.14cGTP binding protein Sey1 (predicted) Positive GeneticPMID:22681890
sre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
rtt109RTT109 family histone lysine acetyltransferase Negative GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
laf1clr6 L associated factor 1 Laf1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
apq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
pck1protein kinase C (PKC)-like Pck1 Positive GeneticPMID:22681890
sgo2inner centromere protein, shugoshin Sgo2 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
slm9hira protein Slm9 Synthetic Growth DefectPMID:18931302
fin1serine/threonine protein kinase, NIMA related Fin1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
pmc2mediator complex subunit Pmc2/Med1 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
bis1stress response protein Bis1 Negative GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
ptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
SPBC25H2.15SSU-rRNA maturation protein Tsr4 homolog 1 (predicted) Negative GeneticPMID:22681890
chp1chromodomain protein Chp1 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
Synthetic Growth DefectPMID:20705239
erp2COPII-coated vesicle component Erp2/3/4 (predicted) Positive GeneticPMID:22681890
alp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:18818364
sec28coatomer epsilon subunit (predicted) Positive GeneticPMID:18818364
air1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
abo2ATPase with bromodomain protein (predicted) Negative GeneticPMID:18818364
rad57RecA family ATPase Rad57/Rhp57 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
rpl90160S ribosomal protein L9 Negative GeneticPMID:22681890
mrc1mediator of replication checkpoint 1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
pyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
vps71Swr1 complex subunit Vps71 Negative GeneticPMID:18818364
pho24-nitrophenylphosphatase Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
tip1CLIP170 family protein Tip1 Negative GeneticPMID:18818364
ppk8serine/threonine protein kinase Ppk8 (predicted) Negative GeneticPMID:22681890
SPBC725.05cnucleotide pyrophosphatase (predicted) Negative GeneticPMID:22681890
ppk16serine/threonine protein kinase Ppk16 (predicted) Negative GeneticPMID:18818364
dad1DASH complex subunit Dad1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
hos2histone deacetylase (class I) Hos2 Positive GeneticPMID:22681890
nda3tubulin beta Nda3 Synthetic Growth DefectPMID:8937982
mfm3M-factor precursor Mfm3 Negative GeneticPMID:22681890
SPAC30D11.14cRNA-binding protein (predicted) Negative GeneticPMID:22681890
sds23PP2A-type phosphatase inhibitor Sds23/Moc1 Positive GeneticPMID:22681890
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
ctu2cytosolic thiouridylase subunit Ctu2 Negative GeneticPMID:22681890
cid12poly(A) polymerase Cid12 Synthetic Growth DefectPMID:20705239
adn2transcription factor (predicted) Negative GeneticPMID:22681890
sim4kinetochore protein, CENP-K ortholog, Sim4 Synthetic Growth DefectPMID:12719471
tcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
chl1ATP-dependent DNA helicase Chl1 (predicted) Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
rho2Rho family GTPase Rho2 Positive GeneticPMID:22681890
SPBC1A4.04sequence orphan Positive GeneticPMID:22681890
moc3transcription factor Moc3 Positive GeneticPMID:22681890
vph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:18818364
SPAC212.08cGPI anchored protein (predicted) Positive GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
gld1mitochondrial glycerol dehydrogenase Gld1 Positive GeneticPMID:22681890
mpc2mitochondrial pyruvate transmembrane transporter Mpc2 (predicted) Positive GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
hrk1haspin related kinase Hrk1 Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
gpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
def1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:22681890
nop10snoRNP pseudouridylase box H/ACA snoRNP complex protein (predicted) Negative GeneticPMID:22681890
SPAC977.05cconserved fungal family Positive GeneticPMID:22681890
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Phenotypic SuppressionPMID:20211136
Positive GeneticPMID:22681890
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
SPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
mug73plasma membrane transmembrane transport regulator (predicted) Negative GeneticPMID:22681890
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
Synthetic Growth DefectPMID:20705239
tos4FHA domain protein Tos4 (predicted) Positive GeneticPMID:22681890
raf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
eme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
Negative GeneticPMID:22681890
wis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Positive GeneticPMID:22681890
dcr1dicer Synthetic Growth DefectPMID:20705239
Dosage Rescue
rpl230160S ribosomal protein L23 Negative GeneticPMID:22681890
swi3replication fork protection complex subunit Swi3 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
tfs1transcription elongation factor TFIIS Positive GeneticPMID:18818364
Positive GeneticPMID:22681890
SPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Negative GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
htb1histone H2B Htb1 Affinity Capture-MSPMID:17114925
Biochemical ActivityPMID:16024659
Affinity Capture-MS
hht1histone H3 h3.1 Affinity Capture-WesternPMID:20705239
ned8ubiquitin-like protein modifier Ned8 Affinity Capture-MSPMID:17114925
rbx1RING-box protein 1, SCF complex ubiquitin ligase subunit Affinity Capture-MSPMID:16024659
raf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Affinity Capture-MSPMID:17114925
Two-hybridPMID:22319459
Affinity Capture-Western
Two-hybridPMID:16040243
Affinity Capture-MSPMID:16024659
Affinity Capture-WesternPMID:20211136
Reconstituted ComplexPMID:24449894
rad2414-3-3 protein Rad24 Affinity Capture-MSPMID:17114925
raf2Rik1-associated factor Raf2 Affinity Capture-MSPMID:21725325
Affinity Capture-MSPMID:17114925
Reconstituted ComplexPMID:24449894
Affinity Capture-MSPMID:16024659
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-WesternPMID:23613586
Affinity Capture-WesternPMID:20211136
Affinity Capture-MS
Affinity Capture-WesternPMID:22319459
Reconstituted ComplexPMID:24449894
ago1argonaute Affinity Capture-WesternPMID:20705239
tas3RITS complex subunit 3 Affinity Capture-WesternPMID:20705239
clr4histone H3 lysine methyltransferase Clr4 Affinity Capture-MSPMID:17114925
Affinity Capture-WesternPMID:22319459
Affinity Capture-MSPMID:16024659
rdp1RNA-directed RNA polymerase Rdp1 Affinity Capture-WesternPMID:20705239
chp1chromodomain protein Chp1 Affinity Capture-WesternPMID:18345014
hht2histone H3 h3.2 Affinity Capture-WesternPMID:20705239
hhf1histone H4 h4.1 Affinity Capture-MSPMID:17114925
pcu4cullin 4 Affinity Capture-WesternPMID:16127433
Affinity Capture-MSPMID:17114925
Reconstituted ComplexPMID:24449894
Affinity Capture-MSPMID:16024659
mlo3RNA binding protein Mlo3 Affinity Capture-WesternPMID:21436456
External References
Database Identifier Description
NBRP SPCC11E10.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC11E10.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC11E10.08 BioGRID Interaction Datasets
Expression Viewer SPCC11E10.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC11E10.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC11E10.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC11E10.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC11E10.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC11E10.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC11E10.08 Cell Cycle Data
GEO SPCC11E10.08 GEO profiles
PInt SPCC11E10.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC11E10.08 Peptides identified in tandem mass spectrometry proteomics experiments
WikiGene2539050silencing protein Rik1
EntrezGene2539050silencing protein Rik1
SPD / RIKEN47/47H06Orfeome Localization Data
UniProtKB/SwissProtQ10426Chromatin modification-related protein rik1
ModBaseQ10426Database of comparative protein structure models
STRINGQ10426Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588204silencing protein Rik1
RefSeq mRNANM_001023194972h- silencing protein Rik1 (rik1), mRNA
European Nucleotide ArchiveAAD24488ENA Protein Mapping
European Nucleotide ArchiveAAD24488.1ENA Protein Mapping
European Nucleotide ArchiveCAB57850ENA Protein Mapping
European Nucleotide ArchiveCAB57850.1ENA Protein Mapping
UniParcUPI00001338F1UniProt Archive

Literature for rik1

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014