rik1 (SPCC11E10.08)


Gene Standard Namerik1 Characterisation Statuspublished
Systematic IDSPCC11E10.08 Feature Typeprotein coding
Synonyms Name Description
Productsilencing protein Rik1 Product Size1040aa, 118.12 kDa
Genomic Location Chromosome III, 1467695-1471912 (4218nt); CDS:1468174-1471296 (3123nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
DNA binding379
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cellular protein localization552
Annotation ExtensionEvidenceWith/FromReference
chromatin silencing at centromere61
Annotation ExtensionEvidenceWith/FromReference
chromatin silencing at centromere outer repeat region26
Annotation ExtensionEvidenceWith/FromReference
chromatin silencing at silent mating-type cassette36
Annotation ExtensionEvidenceWith/FromReference
chromatin silencing at telomere22
Annotation ExtensionEvidenceWith/FromReference
donor selection3
Annotation ExtensionEvidenceWith/FromReference
maintenance of chromatin silencing at silent mating-type cassette3
Annotation ExtensionEvidenceWith/FromReference
meiotic telomere clustering14
Annotation ExtensionEvidenceWith/FromReference
negative regulation of histone H3-K4 methylation5
Annotation ExtensionEvidenceWith/FromReference
NOT telomere maintenance
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
CLRC ubiquitin ligase complex6
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle pole body216
Annotation ExtensionEvidenceWith/FromReference
nuclear chromatin318
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
protein complex1370
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to 5-fluorouracilrik1ΔNull271
sensitive to bortezomibrik1ΔNull256
sensitive to cadmiumrik1ΔNull246
sensitive to salt stressrik1ΔNull91
sensitive to thiabendazolerik1ΔNull219
viable vegetative cell populationrik1ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
abnormal ascospore wall biogenesisrik1ΔNull16
abnormal heterochromatin assembly at centromere outer repeatrik1Not specified2
abolished protein localization to nuclear centromeric heterochromatin6
affecting swi6rik1-304Not specified
decreased chromatin silencing at centromere outer repeat regionrik1-304Not specified35
rik1ΔNull
decreased chromatin silencing at silent mating-type cassetterik1-304Not specified19
rik1ΔNull
decreased chromatin silencing at telomererik1ΔNull25
normal centromere clustering at nuclear peripheryrik1Not specified2
normal centromeric outer repeat transcript-derived siRNA levelrik1ΔNull8
normal conjugation frequencyrik1ΔNull11
viable vegetative cell with normal cell morphologyrik1ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1467695..1471912
mRNA1467695..1471912
5' UTR1467695..1468173AU006880
CDS1468174..1471296
3' UTR1471297..1471912PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03178 Pfam IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminal 712 1000 5
PTHR10644:SF3 HMMPANTHER 1 1040 2
PTHR10644 HMMPANTHER 1 1040 4
Coil ncoils Rabaptin coiled-coil domain 695 716 968
Coil ncoils Rabaptin coiled-coil domain 953 974 968

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190
PBO:0001290rik1/ddb1 subfamilyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001290

Protein Properties

Ave. residue weight 113.58 Da
Charge 0.50
Isoelectric point 6.55
Molecular weight 118.12 kDa
Number of residues 1040
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
377during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
362during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
326during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.5during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.46during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog599
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesago1argonaute Affinity Capture-WesternPMID:20705239
affinity captureschp1chromodomain protein Chp1 Affinity Capture-WesternPMID:18345014
affinity capturesclr4histone H3 lysine methyltransferase Clr4 Affinity Capture-MSPMID:17114925
affinity capturesclr4histone H3 lysine methyltransferase Clr4 Affinity Capture-WesternPMID:22319459
affinity capturesclr4histone H3 lysine methyltransferase Clr4 Affinity Capture-MSPMID:16024659
affinity captureshhf1histone H4 h4.1 Affinity Capture-MSPMID:17114925
affinity captured byhht1histone H3 h3.1 Affinity Capture-WesternPMID:20705239
affinity captured byhht2histone H3 h3.2 Affinity Capture-WesternPMID:20705239
affinity captureshtb1histone H2B Htb1 Affinity Capture-MSPMID:17114925
modifieshtb1histone H2B Htb1 Biochemical ActivityPMID:16024659
affinity captureshtb1histone H2B Htb1 Affinity Capture-MSPMID:16024659
affinity captured bymlo3RNA binding protein Mlo3 Affinity Capture-WesternPMID:21436456
affinity capturesned8ubiquitin-like protein modifier Ned8 Affinity Capture-MSPMID:17114925
affinity capturespcu4cullin 4 Affinity Capture-WesternPMID:16127433
affinity capturespcu4cullin 4 Affinity Capture-MSPMID:17114925
forms complex withpcu4cullin 4 Reconstituted ComplexPMID:24449894
forms complex withpcu4cullin 4 Reconstituted ComplexPMID:24449894
affinity capturespcu4cullin 4 Affinity Capture-MSPMID:16024659
affinity captured bypir2zf-C2H2 type zinc finger protein, implicated in RNAi (predicted) Affinity Capture-MSPMID:24713849
affinity capturesrad2414-3-3 protein Rad24 Affinity Capture-MSPMID:17114925
affinity capturesraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Affinity Capture-MSPMID:17114925
binds activation domain construct withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Two-hybridPMID:22319459
affinity captured byraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Affinity Capture-WesternPMID:22319459
binds DNA-binding domain construct withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Two-hybridPMID:16040243
affinity capturesraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Affinity Capture-MSPMID:16024659
affinity capturesraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Affinity Capture-WesternPMID:20211136
forms complex withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Reconstituted ComplexPMID:24449894
forms complex withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Reconstituted ComplexPMID:24449894
affinity captured byraf2Rik1-associated factor Raf2 Affinity Capture-MSPMID:21725325
affinity captured byraf2Rik1-associated factor Raf2 Affinity Capture-MSPMID:17114925
affinity capturesraf2Rik1-associated factor Raf2 Affinity Capture-MSPMID:17114925
forms complex withraf2Rik1-associated factor Raf2 Reconstituted ComplexPMID:24449894
affinity capturesraf2Rik1-associated factor Raf2 Affinity Capture-MSPMID:16024659
affinity capturesrbx1SCF complex and CLRC ubiquitin ligase ligase E3 subunit Rbx1 Affinity Capture-MSPMID:16024659
affinity captured byrdp1RNA-directed RNA polymerase Rdp1 Affinity Capture-WesternPMID:20705239
affinity captured bystc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-WesternPMID:23613586
affinity captured bystc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-MSPMID:20211136
affinity captured bystc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-WesternPMID:20211136
affinity captured bystc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-WesternPMID:22319459
forms complex withstc1LIM-like protein linking chromatin modification to RNAi, Stc1 Reconstituted ComplexPMID:24449894
affinity captured bytas3RITS complex subunit 3 Affinity Capture-WesternPMID:20705239
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withabo2ATPase with bromodomain protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withadn2transcription factor (predicted) Negative GeneticPMID:22681890
positive genetic interaction withago1argonaute Positive GeneticPMID:18818364
positive genetic interaction withago1argonaute Positive GeneticPMID:22681890
rescued by overexpression ofago1argonaute Dosage RescuePMID:20705239
synthetic growth defect withago1argonaute Synthetic Growth DefectPMID:20705239
negative genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
negative genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:22681890
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
negative genetic interaction withalp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:18818364
negative genetic interaction withapq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
positive genetic interaction witharb1argonaute inhibitor protein 1 Positive GeneticPMID:22681890
negative genetic interaction withark1aurora-B kinase Ark1 Negative GeneticPMID:22681890
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
synthetic growth defect withase1antiparallel microtubule cross-linking factor Ase1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withase1antiparallel microtubule cross-linking factor Ase1 Negative GeneticPMID:18818364
negative genetic interaction withase1antiparallel microtubule cross-linking factor Ase1 Negative GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
negative genetic interaction withasp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withatb2tubulin alpha 2 Negative GeneticPMID:18818364
negative genetic interaction withatb2tubulin alpha 2 Negative GeneticPMID:22681890
negative genetic interaction withath1ataxin-2 homolog Negative GeneticPMID:22681890
positive genetic interaction withbag101BAG family molecular chaperone regulator Bag101 (predicted) Positive GeneticPMID:24497846
negative genetic interaction withbis1splicing factor Bis1 Negative GeneticPMID:22681890
negative genetic interaction withbtf3nascent polypeptide-associated complex beta subunit Negative GeneticPMID:22681890
negative genetic interaction withbub3mitotic spindle checkpoint protein Bub3 Negative GeneticPMID:18818364
negative genetic interaction withbub3mitotic spindle checkpoint protein Bub3 Negative GeneticPMID:22681890
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withcdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
synthetic growth defect withchl1ATP-dependent DNA helicase Chl1 (predicted) Synthetic Growth DefectPMID:18931302
negative genetic interaction withchl1ATP-dependent DNA helicase Chl1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withchl1ATP-dependent DNA helicase Chl1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withchp1chromodomain protein Chp1 Positive GeneticPMID:18818364
positive genetic interaction withchp1chromodomain protein Chp1 Positive GeneticPMID:22681890
synthetic growth defect withchp1chromodomain protein Chp1 Synthetic Growth DefectPMID:20705239
synthetic growth defect withcid12poly(A) polymerase Cid12 Synthetic Growth DefectPMID:20705239
synthetic growth defect withclp1Cdc14-related protein phosphatase Clp1/Flp1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withclp1Cdc14-related protein phosphatase Clp1/Flp1 Negative GeneticPMID:22681890
synthetic growth defect withclr3histone deacetylase (class II) Clr3 Synthetic Growth DefectPMID:18931302
negative genetic interaction withclr3histone deacetylase (class II) Clr3 Negative GeneticPMID:18818364
negative genetic interaction withclr3histone deacetylase (class II) Clr3 Negative GeneticPMID:22681890
positive genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:18818364
rescuesclr4histone H3 lysine methyltransferase Clr4 Phenotypic SuppressionPMID:20211136
positive genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:22681890
rescued by overexpression ofclr4histone H3 lysine methyltransferase Clr4 Dosage RescuePMID:20705239
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:18818364
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
negative genetic interaction withcsk1cyclin-dependent kinase/ cyclin-dependent kinase activating kinase Csk1 Negative GeneticPMID:22681890
synthetic growth defect withctu1cytosolic thiouridylase subunit Ctu1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withctu1cytosolic thiouridylase subunit Ctu1 Negative GeneticPMID:22681890
negative genetic interaction withctu2cytosolic thiouridylase subunit Ctu2 Negative GeneticPMID:22681890
negative genetic interaction withcwf19complexed with Cdc5 protein Cwf19 Negative GeneticPMID:22681890
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:18818364
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
positive genetic interaction withdbl5ubiquitin-protein ligase E3 Dbl5 Positive GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:18818364
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
negative genetic interaction withdcc1Ctf18 RFC-like complex subunit Dcc1 Negative GeneticPMID:22681890
synthetic growth defect withdcr1dicer Synthetic Growth DefectPMID:20705239
rescued by overexpression ofdcr1dicer Dosage RescuePMID:20705239
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:18818364
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
negative genetic interaction withdef1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
negative genetic interaction withdsc4Golgi Dsc E3 ligase complex subunit Dsc4 Negative GeneticPMID:21504829
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
negative genetic interaction withelp1elongator subunit Elp1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp1elongator subunit Elp1 (predicted) Negative GeneticPMID:22681890
synthetic growth defect withelp3elongator complex subunit Elp3 (predicted) Synthetic Growth DefectPMID:18931302
negative genetic interaction withelp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withelp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp6elongator complex subunit Elp6 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp6elongator complex subunit Elp6 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witheme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
negative genetic interaction witheme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:22681890
positive genetic interaction witherf2palmitoyltransferase Erf2 Positive GeneticPMID:22681890
positive genetic interaction witherp2COPII-coated vesicle component Erp2/3/4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withers1RNA-silencing factor Ers1 Positive GeneticPMID:18818364
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
synthetic growth defect withfhl1forkhead transcription factor Fhl1 Synthetic Growth DefectPMID:18931302
synthetic growth defect withfin1serine/threonine protein kinase, NIMA related Fin1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:18818364
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
negative genetic interaction withfkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withfkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Negative GeneticPMID:18818364
positive genetic interaction withfta6Mis6-Sim4 complex Fta6 Positive GeneticPMID:22681890
negative genetic interaction withgar2nucleolar protein required for rRNA processing Negative GeneticPMID:22681890
positive genetic interaction withgld1mitochondrial glycerol dehydrogenase Gld1 Positive GeneticPMID:22681890
negative genetic interaction withgmh5alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
positive genetic interaction withgsk3serine/threonine protein kinase Gsk3 Positive GeneticPMID:22681890
negative genetic interaction withhap2HMG box protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withhhf2histone H4 h4.2 Positive GeneticPMID:22681890
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
positive genetic interaction withhos2histone deacetylase (class I) Hos2 Positive GeneticPMID:22681890
negative genetic interaction withhrk1haspin related kinase Hrk1 Negative GeneticPMID:22681890
positive genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Positive GeneticPMID:18818364
positive genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Positive GeneticPMID:22681890
synthetic growth defect withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Synthetic Growth DefectPMID:20705239
negative genetic interaction withimp1importin alpha Negative GeneticPMID:22681890
negative genetic interaction withisu1mitochondrial iron-sulfur cluster assembly scaffold protein Isu1 Negative GeneticPMID:22681890
positive genetic interaction withiwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
negative genetic interaction withlaf1Clr6 L associated factor 1 Laf1 Negative GeneticPMID:18818364
negative genetic interaction withlaf1Clr6 L associated factor 1 Laf1 Negative GeneticPMID:22681890
positive genetic interaction withlos1karyopherin exportin T Los1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withlsc1Lsk1 associated cyclin Negative GeneticPMID:22681890
negative genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
negative genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:22681890
negative genetic interaction withmad2mitotic spindle checkpoint protein Mad2 Negative GeneticPMID:18818364
negative genetic interaction withmad2mitotic spindle checkpoint protein Mad2 Negative GeneticPMID:22681890
synthetic growth defect withmal3EB1 family Mal3 Synthetic Growth DefectPMID:18931302
negative genetic interaction withmal3EB1 family Mal3 Negative GeneticPMID:18818364
negative genetic interaction withmal3EB1 family Mal3 Negative GeneticPMID:22681890
negative genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
negative genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:22681890
negative genetic interaction withmed13mediator complex subunit Srb9 Negative GeneticPMID:18818364
positive genetic interaction withmed20mediator complex subunit Med20 Positive GeneticPMID:18818364
positive genetic interaction withmed6mediator complex subunit Med6 Positive GeneticPMID:18818364
negative genetic interaction withmfm3M-factor precursor Mfm3 Negative GeneticPMID:22681890
negative genetic interaction withmgr2TIM23 translocase complex subunit Mgr2 (predicted) Negative GeneticPMID:22681890
synthetic growth defect withmis6inner centromere protein, CENP-I ortholog Mis6 Synthetic Growth DefectPMID:12719471
positive genetic interaction withmms19Dos2 silencing complex subunit Mms19 Positive GeneticPMID:18818364
positive genetic interaction withmoc3transcription factor Moc3 Positive GeneticPMID:22681890
negative genetic interaction withmpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmpc2mitochondrial pyruvate transmembrane transporter Mpc2 (predicted) Positive GeneticPMID:22681890
synthetic growth defect withmph1dual specificity protein kinase Mph1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withmph1dual specificity protein kinase Mph1 Negative GeneticPMID:18818364
negative genetic interaction withmph1dual specificity protein kinase Mph1 Negative GeneticPMID:22681890
synthetic growth defect withmrc1mediator of replication checkpoint 1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withmrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
negative genetic interaction withmre11Mre11 nuclease Negative GeneticPMID:18818364
negative genetic interaction withmsd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
synthetic growth defect withmsh6MutS protein homolog Synthetic Growth DefectPMID:18931302
negative genetic interaction withmsh6MutS protein homolog Negative GeneticPMID:22681890
negative genetic interaction withmsy1MS calcium ion channel protein Msy1 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:18818364
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withmug73plasma membrane transmembrane transport regulator (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmug80cyclin Clg1 (predicted) Positive GeneticPMID:22681890
synthetic growth defect withnda3tubulin beta Nda3 Synthetic Growth DefectPMID:8937982
negative genetic interaction withnht1Ino80 complex HMG box subunit Nht1 Negative GeneticPMID:22681890
negative genetic interaction withnop10snoRNP pseudouridylase box H/ACA snoRNP complex protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnop16ribosome biogenesis protein Nop16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnpp1nucleotide pyrophosphatase Npp1 (predicted) Negative GeneticPMID:22681890
synthetic growth defect withnse5Smc5-6 complex non-SMC subunit Nse5 Synthetic Growth DefectPMID:18931302
negative genetic interaction withnup124nucleoporin Nup124 Negative GeneticPMID:22681890
positive genetic interaction withnup132nucleoporin Nup132 Positive GeneticPMID:22681890
negative genetic interaction withnup61nucleoporin Nup61 Negative GeneticPMID:18818364
negative genetic interaction withpac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
positive genetic interaction withpas4peroxisomal ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withpca1metacaspase Pca1 Negative GeneticPMID:22681890
positive genetic interaction withpck1protein kinase C (PKC)-like Pck1 Positive GeneticPMID:22681890
negative genetic interaction withpds5mitotic cohesin-associated protein Pds5 Negative GeneticPMID:18818364
negative genetic interaction withpds5mitotic cohesin-associated protein Pds5 Negative GeneticPMID:22681890
negative genetic interaction withpho24-nitrophenylphosphatase Negative GeneticPMID:18818364
negative genetic interaction withpho24-nitrophenylphosphatase Negative GeneticPMID:22681890
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:18818364
positive genetic interaction withplr1pyridoxal reductase Plr1 Positive GeneticPMID:22681890
negative genetic interaction withpmc1mediator complex subunit Pmc1 Negative GeneticPMID:18818364
positive genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Positive GeneticPMID:18818364
positive genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Positive GeneticPMID:22681890
positive genetic interaction withpmk1MAP kinase Pmk1 Positive GeneticPMID:22681890
negative genetic interaction withpnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:18818364
negative genetic interaction withpph3serine/threonine protein phosphatase, PP4 complex subunit Pph3 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withpph3serine/threonine protein phosphatase, PP4 complex subunit Pph3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppk16serine/threonine protein kinase Ppk16 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withppk8serine/threonine protein kinase Ppk8 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withpsl1cyclin pho85 family Psl1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withpsy2protein phosphatase PP4 complex subunit Psy2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
negative genetic interaction withpyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
negative genetic interaction withpzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
negative genetic interaction withrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Negative GeneticPMID:22681890
negative genetic interaction withrad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:18818364
negative genetic interaction withrad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
synthetic growth defect withrad57RecA family ATPase Rad57/Rhp57 Synthetic Growth DefectPMID:18931302
negative genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:18818364
positive genetic interaction withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Positive GeneticPMID:18818364
positive genetic interaction withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Positive GeneticPMID:22681890
positive genetic interaction withraf2Rik1-associated factor Raf2 Positive GeneticPMID:18818364
positive genetic interaction withraf2Rik1-associated factor Raf2 Positive GeneticPMID:22681890
positive genetic interaction withrap1telomere binding protein Rap1 Positive GeneticPMID:22681890
positive genetic interaction withrdp1RNA-directed RNA polymerase Rdp1 Positive GeneticPMID:18818364
positive genetic interaction withrdp1RNA-directed RNA polymerase Rdp1 Positive GeneticPMID:22681890
synthetic growth defect withrdp1RNA-directed RNA polymerase Rdp1 Synthetic Growth DefectPMID:20705239
positive genetic interaction withrds1conserved fungal protein Positive GeneticPMID:22681890
negative genetic interaction withres1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
negative genetic interaction withrev7DNA polymerase zeta Rev7 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withrho2Rho family GTPase Rho2 Positive GeneticPMID:22681890
positive genetic interaction withrpb9DNA-directed RNA polymerase II complex subunit Rpb9 Positive GeneticPMID:18818364
positive genetic interaction withrpb9DNA-directed RNA polymerase II complex subunit Rpb9 Positive GeneticPMID:22681890
negative genetic interaction withrpl170260S ribosomal protein L17 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl230160S ribosomal protein L23 Negative GeneticPMID:22681890
negative genetic interaction withrpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
negative genetic interaction withrpl430260S ribosomal protein L37a (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl90160S ribosomal protein L9 Negative GeneticPMID:22681890
negative genetic interaction withrps00140S ribosomal protein S0A (p40) Negative GeneticPMID:22681890
negative genetic interaction withrps80140S ribosomal protein S8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrtt109RTT109 family histone lysine acetyltransferase Negative GeneticPMID:22681890
negative genetic interaction withryh1GTPase Ryh1 Negative GeneticPMID:22681890
positive genetic interaction withsce3translation initiation factor (predicted) Positive GeneticPMID:22681890
synthetic growth defect withscm3CENP-A chaperone Scm3 Synthetic Growth DefectPMID:12719471
positive genetic interaction withsds23PP2A-type phosphatase inhibitor Sds23/Moc1 Positive GeneticPMID:22681890
positive genetic interaction withsec28coatomer epsilon subunit (predicted) Positive GeneticPMID:18818364
negative genetic interaction withser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withset1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
positive genetic interaction withsey1GTP binding protein Sey1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withsfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withsgf73SAGA complex subunit Sgf73 Positive GeneticPMID:25076038
negative genetic interaction withsgo1inner centromere protein, shugoshin, Sgo1 Negative GeneticPMID:22681890
negative genetic interaction withsgo2inner centromere protein, shugoshin Sgo2 Negative GeneticPMID:18818364
negative genetic interaction withsgo2inner centromere protein, shugoshin Sgo2 Negative GeneticPMID:22681890
synthetic growth defect withsim4kinetochore protein, CENP-K ortholog, Sim4 Synthetic Growth DefectPMID:12719471
synthetic growth defect withslm9hira protein Slm9 Synthetic Growth DefectPMID:18931302
positive genetic interaction withsnf5SWI/SNF complex subunit Snf5 Positive GeneticPMID:22681890
positive genetic interaction withSPAC1071.05S-adenosylmethionine-dependent methyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC17H9.13cglutamate 5-kinase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC18G6.13Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC212.08cS. pombe specific GPI anchored protein family 1 Positive GeneticPMID:22681890
negative genetic interaction withSPAC24B11.05pyrimidine 5'-nucleotidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC30D11.14cRNA-binding protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC513.07flavonol reductase/cinnamoyl-CoA reductase family Positive GeneticPMID:22681890
negative genetic interaction withSPAC521.03short chain dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC6G9.14RNA-binding protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC750.08cNAD-dependent malic enzyme (predicted), partial Positive GeneticPMID:22681890
positive genetic interaction withSPAC977.05cconserved fungal family Positive GeneticPMID:22681890
negative genetic interaction withSPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC16G5.03ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Positive GeneticPMID:22681890
positive genetic interaction withSPBC1861.05pseudouridine-metabolizing bifunctional protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC1A4.04Schizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC25H2.15SSU-rRNA maturation protein Tsr4 homolog 1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBP8B7.18cphosphomethylpyrimidine kinase (predicted) Positive GeneticPMID:18818364
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:18818364
negative genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC594.04csteroid oxidoreductase superfamily protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspf38U5 snRNP complex subunit Spf38 Negative GeneticPMID:22681890
negative genetic interaction withsrb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Negative GeneticPMID:22681890
negative genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:22681890
negative genetic interaction withsre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
rescuesstc1LIM-like protein linking chromatin modification to RNAi, Stc1 Phenotypic SuppressionPMID:20211136
positive genetic interaction withstc1LIM-like protein linking chromatin modification to RNAi, Stc1 Positive GeneticPMID:22681890
negative genetic interaction withsum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
negative genetic interaction withswc5Swr1 complex subunit Swc5 Negative GeneticPMID:18818364
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
synthetic growth defect withswi3replication fork protection complex subunit Swi3 Synthetic Growth DefectPMID:18931302
negative genetic interaction withswi3replication fork protection complex subunit Swi3 Negative GeneticPMID:18818364
positive genetic interaction withtas3RITS complex subunit 3 Positive GeneticPMID:18818364
enhances phenotype oftas3RITS complex subunit 3 Phenotypic EnhancementPMID:21060862
synthetic growth defect withtas3RITS complex subunit 3 Synthetic Growth DefectPMID:20705239
negative genetic interaction withtcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:18818364
negative genetic interaction withtcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:22681890
negative genetic interaction withtea2kinesin-like protein Tea2 Negative GeneticPMID:18818364
positive genetic interaction withtfs1transcription elongation factor TFIIS Positive GeneticPMID:18818364
positive genetic interaction withtfs1transcription elongation factor TFIIS Positive GeneticPMID:22681890
negative genetic interaction withtif38translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
negative genetic interaction withtip1CLIP170 family protein Tip1 Negative GeneticPMID:18818364
synthetic growth defect withtlg2SNARE Tlg2 (predicted) Synthetic Growth DefectPMID:18931302
positive genetic interaction withtma20RNA-binding protein Tma20 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withtos4FHA domain protein Tos4 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withura3dihydroorotate dehydrogenase Ura3 Negative GeneticPMID:22681890
positive genetic interaction withvht1vitamin H transmembrane transporter Vht1 Positive GeneticPMID:22681890
negative genetic interaction withvph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withvps71Swr1 complex subunit Vps71 Negative GeneticPMID:18818364
positive genetic interaction withwis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Positive GeneticPMID:22681890
positive genetic interaction withxap5xap-5-like protein Positive GeneticPMID:24957674
negative genetic interaction withyar1ribosome biogenesis protein Yar1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:18818364
negative genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
negative genetic interaction withzip1transcription factor Zip1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC11E10.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC11E10.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC11E10.08 BioGRID Interaction Datasets
Expression Viewer SPCC11E10.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC11E10.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC11E10.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC11E10.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC11E10.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC11E10.08 Transcriptome Viewer (Bähler Lab)
GEO SPCC11E10.08 GEO profiles
PInt SPCC11E10.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC11E10.08 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC11E10.08 Fission yeast phenotypic data & analysis
Cyclebase SPCC11E10.08.1 Cell Cycle Data
SPD / RIKEN47/47H06Orfeome Localization Data
UniProtKB/SwissProtQ10426Chromatin modification-related protein rik1
ModBaseQ10426Database of comparative protein structure models
STRINGQ10426Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588204silencing protein Rik1
RefSeq mRNANM_001023194972h- silencing protein Rik1 (rik1), mRNA
European Nucleotide ArchiveAAD24488.1ENA Protein Mapping
European Nucleotide ArchiveCAB57850.1ENA Protein Mapping
UniParcUPI00001338F1UniProt Archive

Literature for rik1

Search: Europe PMC or PubMed

Release Version: PomBase:26_52 - 11 May 2015