SPCC1235.03

Gene Standard NameUnassigned ChromosomeIII
Systematic IDSPCC1235.03 Gene Start178975
Synonyms Gene End180813
ProductSMR domain protein, possibly involved in DNA repair Gene Length1839
Feature Typeprotein coding CDS Start179039
Name Description CDS End180586
Characterisation Statusconserved_unknown CDS Length1548

Ensembl Gene Location
  1. SPNCRNA.1115
  2. SPNCRNA.458
  3. SPNCRNA.1116
  4. SPCC1235.01
  5. bio2
  6. SPCC1235.03
  7. SPCC1235.04c
  8. fft2
  9. SPNCRNA.1117
  10. vma21
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPCC1235.03delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0043130ubiquitin bindingNASGO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006281DNA repairISMPFAM:PF01713GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005730nucleolusIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1178975179065
2179105180813

References

Region Start End Reference
five_prime_UTR178975179038PMID:21511999
five_prime_UTR178975179038PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01713 IPR002625 Pfam Smr protein/MutS2 C-terminal 412 490 2
SM00463 IPR002625 SMART Smr protein/MutS2 C-terminal 409 492 2
PS50828 IPR002625 Prosite Profiles Smr protein/MutS2 C-terminal 412 495 2
SSF160443 SuperFamily 411 490 2

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0001235CUE domain proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001235

Protein Properties

Ave. residue weight 114.53 Da
Charge -3.00
Isoelectric point 6.24
Molecular weight 57.50 kDa
Number of residues 502
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.92PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.36PMID:23101633
Warning
DescriptionQualifierReference
gene structure updated PMID:21511999
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
SPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Positive GeneticPMID:22681890
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
prp1U4/U6 x U5 tri-snRNP complex subunit Prp1 Positive GeneticPMID:22681890
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPCC1235.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1235.03 Retrieval of eukaryotic orthologs
BioGrid SPCC1235.03 BioGRID Interaction Datasets
Bähler Lab SPCC1235.03 Cell Cycle Expression Profile
Bähler Lab SPCC1235.03 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC1235.03 Pheromone response/mating expression profiles
Bähler Lab SPCC1235.03 Environmental stress expression profiles
Bähler Lab SPCC1235.03 Bähler Lab Transcriptome Viewer
Cyclebase SPCC1235.03 Cell Cycle Data
PInt SPCC1235.03 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC1235.03 Entrez Gene
EntrezGene2539296SMR domain protein, possibly involved in DNA repair
WikiGene2539296SMR domain protein, possibly involved in DNA repair
SPD / RIKEN19/19B12Orfeome Localization Data
UniProtKB/SwissProtO74840Smr domain-containing protein C1235.03
ModBaseO74840Database of comparative protein structure models
Pfam Protein DomainsO74840Pfam Domain Arrangement
RefSeq PeptideNP_587729SMR domain protein, possibly involved in DNA repair
RefSeq mRNANM_001022724972h- SMR domain protein, possibly involved in DNA repair (SPCC1235.03), mRNA
European Nucleotide ArchiveBAA13833ENA Protein Mapping
European Nucleotide ArchiveCAA21107ENA Protein Mapping
UniParcUPI000228F4AFUniProt Archive

Literature for SPCC1235.03
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013