ght5 (SPCC1235.14)


Gene Standard Nameght5 Characterisation Statuspublished
Systematic IDSPCC1235.14 Feature Typeprotein coding
Synonyms Name Description
Producthexose transporter Ght5 Product Size546aa, 60.32 kDa
Genomic Location Chromosome III, 212160-214376 (2217nt); CDS:212313-213953 (1641nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0055054fructose:proton symporter activityIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:107358573
GO:0005358high-affinity hydrogen:glucose symporter activityIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:107358573
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0098655cation transmembrane transportIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:10735857123
GO:0032445fructose importIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:107358574
GO:0046323glucose importIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:107358574
GO:0035428hexose transmembrane transportIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:107358578
GO:0015992proton transportIGISGD:S000001136, SGD:S000002753, SGD:S000004613, SGD:S000001138, SGD:S000001134, SGD:S000002750, SGD:S000002751PMID:1073585750
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005887integral component of plasma membraneICGO:0005358PMID:1073585750
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyght5ΔNullPMID:204732893751
Microscopyght5ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyght5ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1212160214376
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 General substrate transporter 11 467 15
TMhelix TMHMM 304 326 959
TMhelix TMHMM 7 29 959
TMhelix TMHMM 89 111 959
TMhelix TMHMM 403 425 959
TMhelix TMHMM 331 353 959
TMhelix TMHMM 118 135 959
TMhelix TMHMM 180 199 959
TMhelix TMHMM 145 167 959
TMhelix TMHMM 368 390 959
TMhelix TMHMM 429 451 959
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 55
PS00216 Prosite Patterns IPR005829 Sugar transporter, conserved site 318 335 15
PTHR24063 HMMPANTHER 6 489 11
PTHR24063:SF98 HMMPANTHER 6 489 8
1.20.1250.20 Gene3D 50 204 72
1.20.1250.20 Gene3D 263 457 72
SSF103473 SuperFamily IPR016196 Major facilitator superfamily domain, general substrate transporter 8 465 76
SignalP-noTM signalp 1 21 212
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
TIGR00879 tigrfam IPR003663 Sugar/inositol transporter 7 463 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.48 Da
Charge -3.00
Isoelectric point 5.90
Molecular weight 60.32 kDa
Number of residues 546
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS536PMID:217125471670
present during mitotic M phase
present during mitotic M phaseS537PMID:21712547
MOD:00047O-phospho-L-threonineT485PMID:24763107690
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
96862during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
104327during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
95738during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
102458during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
59226.53during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
102412during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
10138.36during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
28during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Genome Organisation
DescriptionQualifierReferenceCount
tandem duplication30
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4599
conserved in eukaryotes4514
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
paa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:22119525
External References
Database Identifier Description
NBRP SPCC1235.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1235.14 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1235.14 BioGRID Interaction Datasets
Expression Viewer SPCC1235.14 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1235.14 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1235.14 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1235.14 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1235.14 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1235.14 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1235.14 Cell Cycle Data
GEO SPCC1235.14 GEO profiles
PInt SPCC1235.14 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1235.14 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN34/34E03Orfeome Localization Data
UniProtKB/SwissProtP78831High-affinity glucose transporter ght5
ModBaseP78831Database of comparative protein structure models
STRINGP78831Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587740hexose transporter Ght5
RefSeq mRNANM_001022735972h- hexose transporter Ght5 (ght5), mRNA
European Nucleotide ArchiveAF051141ENA EMBL mapping
European Nucleotide ArchiveD89179ENA EMBL mapping
European Nucleotide ArchiveCAA21118.1ENA Protein Mapping
UniParcUPI000012B422UniProt Archive

Literature for ght5

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014