gyp2 (SPCC1259.11c)

Gene Standard Namegyp2 ChromosomeIII
Systematic IDSPCC1259.11c Gene Start1056194
Synonyms Gene End1053669
ProductGTPase activating protein Gyp2 (predicted) Gene Length2526
Feature Typeprotein coding CDS Start1056028
Name Description CDS End1053866
Characterisation Statusbiological_role_inferred CDS Length2163

Ensembl Gene Location
  1. rxt3
  2. SPCC1259.08
  3. pdx1
  4. pgp1
  5. gyp2
  6. SPCC1259.12c
  7. SPNCRNA.1171
  8. ubc11
  9. chk1
  10. meu27
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopygyp2delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005097Rab GTPase activator activityISMPFAM:PF00566GO_REF:0000001
GO:0005509calcium ion bindingIEAIPR011992GO_REF:0000002
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0016192vesicle-mediated transportNASGO_REF:0000051
GO:0032313regulation of Rab GTPase activityISMPFAM:PF00566GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
110561941053669

References

Region Start End Reference
three_prime_UTR10538651053669PMID:21511999
five_prime_UTR10561941056029PMID:21511999
three_prime_UTR10538651053669PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF02893 IPR004182 Pfam GRAM 24 84 2
PF00566 IPR000195 Pfam Rab-GTPase-TBC domain 220 424 13
SM00164 IPR000195 SMART Rab-GTPase-TBC domain 213 427 13
SM00568 IPR004182 SMART GRAM 20 85 2
PS50086 IPR000195 Prosite Profiles Rab-GTPase-TBC domain 216 404 13
G3DSA:1.10.8.270 Gene3D 208 329 12
G3DSA:1.10.238.10 IPR011992 Gene3D 547 695 20
SSF47923 IPR000195 SuperFamily 341 441 13
SSF47923 IPR000195 SuperFamily 190 363 13
SSF47473 SuperFamily 505 693 21
PTHR22957:SF48 hmmpanther 149 468 2
PTHR22957 hmmpanther 149 468 12

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0002976GRAM domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0002976

Protein Properties

Ave. residue weight 114.93 Da
Charge -12.50
Isoelectric point 5.20
Molecular weight 82.75 kDa
Number of residues 720
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.41PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide1.7PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPCC1259.11c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1259.11c Retrieval of eukaryotic orthologs
BioGrid SPCC1259.11c BioGRID Interaction Datasets
Bähler Lab SPCC1259.11c Cell Cycle Expression Profile
Bähler Lab SPCC1259.11c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC1259.11c Pheromone response/mating expression profiles
Bähler Lab SPCC1259.11c Environmental stress expression profiles
Bähler Lab SPCC1259.11c Bähler Lab Transcriptome Viewer
Cyclebase SPCC1259.11c Cell Cycle Data
PInt SPCC1259.11c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC1259.11c Entrez Gene
EntrezGene2539140GTPase activating protein Gyp2 (predicted)
Uniprot_genenameGYP2
WikiGene2539140GTPase activating protein Gyp2 (predicted)
UniProtKB/SwissProtO94711GTPase-activating protein gyp2
ModBaseO94711Database of comparative protein structure models
Pfam Protein DomainsO94711Pfam Domain Arrangement
RefSeq PeptideNP_588067GTPase activating protein Gyp2 (predicted)
RefSeq mRNANM_001023059972h- GTPase activating protein Gyp2 (predicted) (gyp2), mRNA
European Nucleotide ArchiveCAA22549ENA Protein Mapping
SPD / RIKEN37/37G02Orfeome Localization Data
UniParcUPI000006999CUniProt Archive

Literature for gyp2
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013