SPCC126.12

Gene Standard NameUnassigned ChromosomeIII
Systematic IDSPCC126.12 Gene Start2137595
Synonyms Gene End2139203
ProductNGG1 interacting factor 3 family, implicated in transcription Gene Length1609
Feature Typeprotein coding CDS Start2138121
Name Description CDS End2139127
Characterisation Statusconserved_unknown CDS Length1007

Ensembl Gene Location
  1. SPCC126.08c
  2. zip2
  3. iah1
  4. SPCC126.11c
  5. SPCC126.12
  6. SPCTRNAASP.08
  7. SPCC126.13c
  8. prp18
  9. sec65
  10. lsm2
  11. wtf23
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopySPCC126.12delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006351transcription, DNA-dependentISMPFAM:PF01784GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005737cytoplasmISOSGD:S000003189GO_REF:0000024
GO:0005739mitochondrionISOSGD:S000003189GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121375952138334
221383882138702
321387552138925
421389912139203

References

Region Start End Reference
three_prime_UTR21391282139203PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01784 IPR002678 Pfam Ngg1p interacting factor 3, NIF3 10 256 1
SSF102705 IPR002678 SuperFamily 9 276 1
PTHR13799 IPR002678 hmmpanther Ngg1p interacting factor 3, NIF3 1 278 1
PTHR13799:SF13 hmmpanther 1 278 1
TIGR00486 IPR002678 tigrfam Ngg1p interacting factor 3, NIF3 9 274 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.38 Da
Charge 0.00
Isoelectric point 6.51
Molecular weight 29.85 kDa
Number of residues 278
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide3958.45PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2265.03PMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide3.2PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.5PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
conserved in archaea
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
SPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
vph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Positive GeneticPMID:22681890
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
kin1microtubule affinity-regulating kinase Kin1 Positive GeneticPMID:22681890
fft3fun thirty related protein Fft3 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPCC126.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC126.12 Retrieval of eukaryotic orthologs
BioGrid SPCC126.12 BioGRID Interaction Datasets
Bähler Lab SPCC126.12 Cell Cycle Expression Profile
Bähler Lab SPCC126.12 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC126.12 Pheromone response/mating expression profiles
Bähler Lab SPCC126.12 Environmental stress expression profiles
Bähler Lab SPCC126.12 Bähler Lab Transcriptome Viewer
Cyclebase SPCC126.12 Cell Cycle Data
PInt SPCC126.12 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC126.12 Entrez Gene
SPD / RIKEN14/14H02Orfeome Localization Data
WikiGene2539063NGG1p interacting factor 3 family
EntrezGene2539063NGG1p interacting factor 3 family
UniProtKB/SwissProtO94404Protein NIF3 homolog
ModBaseO94404Database of comparative protein structure models
Pfam Protein DomainsO94404Pfam Domain Arrangement
RefSeq PeptideNP_588455NGG1p interacting factor 3 family
RefSeq mRNANM_001023446972h- NGG1p interacting factor 3 family (SPCC126.12), mRNA
European Nucleotide ArchiveCAA22481ENA Protein Mapping
SPD / RIKEN14/14H02Orfeome Localization Data

Literature for SPCC126.12
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013