prp18 (SPCC126.14)

Gene Standard Nameprp18 ChromosomeIII
Systematic IDSPCC126.14 Gene Start2140983
Synonyms Gene End2143550
ProductU5 snRNP-associated protein Prp18 (predicted) Gene Length2568
Feature Typeprotein coding CDS Start2141190
Name Description CDS End2142266
Characterisation Statusbiological_role_inferred CDS Length1077

Ensembl Gene Location
  1. iah1
  2. SPCC126.11c
  3. SPCC126.12
  4. SPCTRNAASP.08
  5. SPCC126.13c
  6. prp18
  7. sec65
  8. lsm2
  9. wtf23
  10. mug163
  11. mug55
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001489inviable vegetative cellMicroscopyprp18delta (deletion)deletionPMID:20473289
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0045292mRNA cis splicing, via spliceosomeISOSGD:S000003238GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005681spliceosomal complexISOSGD:S000003238GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121409832142146
221421922143550

References

Region Start End Reference
three_prime_UTR21422672143550PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF02840 IPR004098 Pfam Prp18 195 336 1
PF08799 IPR014906 Pfam Pre-mRNA processing factor 4 (PRP4)-like 129 158 2
SM00500 IPR003648 SMART Splicing factor motif 124 173 2
G3DSA:1.20.940.10 IPR004098 Gene3D 176 337 1
SSF47938 IPR004098 SuperFamily 165 335 1
SSF158230 SuperFamily 111 159 2
Coil ncoils Rabaptin coiled-coil domain 1 22 974
Coil ncoils Rabaptin coiled-coil domain 41 79 974
PTHR13007 hmmpanther 1 341 1
PTHR13007:SF4 hmmpanther 1 341 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 117.48 Da
Charge 7.50
Isoelectric point 9.17
Molecular weight 40.30 kDa
Number of residues 343
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide926.8PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide236.25PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.4PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1.5PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPCC126.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC126.14 Retrieval of eukaryotic orthologs
BioGrid SPCC126.14 BioGRID Interaction Datasets
Bähler Lab SPCC126.14 Cell Cycle Expression Profile
Bähler Lab SPCC126.14 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC126.14 Pheromone response/mating expression profiles
Bähler Lab SPCC126.14 Environmental stress expression profiles
Bähler Lab SPCC126.14 Bähler Lab Transcriptome Viewer
Cyclebase SPCC126.14 Cell Cycle Data
PInt SPCC126.14 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC126.14 Entrez Gene
SPD / RIKEN16/16F08Orfeome Localization Data
WikiGene2539357U5 snRNP-associated protein Prp18
Uniprot_genenamePRP18
EntrezGene2539357U5 snRNP-associated protein Prp18
UniProtKB/SwissProtO94406Pre-mRNA-splicing factor 18
ModBaseO94406Database of comparative protein structure models
Pfam Protein DomainsO94406Pfam Domain Arrangement
RefSeq PeptideNP_588457U5 snRNP-associated protein Prp18
RefSeq mRNANM_001023448972h- U5 snRNP-associated protein Prp18 (prp18), mRNA
European Nucleotide ArchiveBAA87243ENA Protein Mapping
European Nucleotide ArchiveCAA22483ENA Protein Mapping
SPD / RIKEN16/16F08Orfeome Localization Data

Literature for prp18
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013