trp1322 (SPCC1322.03)

Gene Standard Nametrp1322 ChromosomeIII
Systematic IDSPCC1322.03 Gene Start1287903
Synonyms Gene End1291811
ProductTRP-like ion channel (predicted) Gene Length3909
Feature Typeprotein coding CDS Start1288137
Name Description CDS End1290725
Characterisation Statuspublished CDS Length2589

Ensembl Gene Location
  1. ssb3
  2. rpm1
  3. SPCC1322.02
  4. SPNCRNA.1184
  5. trp1322
  6. SPNCRNA.122
  7. fyu1
  8. SPCC1322.05c
  9. kap113
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000085sensitive to camptothecincompetitive growth assay evidencetrp1322delta (deletion)deletionPMID:20537132
FYPO:0000266sensitive to DNA damaging agentscompetitive growth assay evidencetrp1322delta (deletion)deletionPMID:20537132
FYPO:0000961normal cell population growth on sorbitolCell growth assaySPCC1322.03delta (deletion)deletionPECO:0000005, PECO:0000102PMID:21811607
FYPO:0001037normal cell population growth during cellular response to salt stressCell growth assaySPCC1322.03delta (deletion)deletionPECO:0000031, PECO:0000005, PECO:0000102PMID:21811607
Cell growth assaySPCC1322.03delta (deletion)deletionPECO:0000038, PECO:0000102, PECO:0000005PMID:21811607
Cell growth assaySPCC1322.03delta (deletion)deletionPECO:0000092, PECO:0000005, PECO:0000102PMID:21811607
FYPO:0001197decreased cellular calcium levelSubstance quantificationSPCC1322.03delta (deletion)deletionPECO:0000160PMID:21811607
Substance quantificationSPCC1322.03delta (deletion)deletionPMID:21811607
FYPO:0001199normal cellular calcium levelSubstance quantificationSPCC1322.03+ (wild type)wild_typeOverexpressionPECO:0000160PMID:21811607
FYPO:0001376normal cellular calcium level during cellular response to salt stressSubstance quantificationSPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
FYPO:0001377decreased cellular calcium level during cellular response to salt stressReporter gene assaySPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
Substance quantificationSPCC1322.03+ (wild type)wild_typeOverexpressionPECO:0000160PMID:21811607
Reporter gene assaySPCC1322.03delta (deletion)deletionPECO:0000160PMID:21811607
Reporter gene assaySPCC1322.03delta (deletion)deletionPMID:21811607
FYPO:0001459increased basal transcription from CDRE promoterReporter gene assaySPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
Reporter gene assaySPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
Reporter gene assaySPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
FYPO:0001460increased duration of positive regulation of transcription from CDRE promoter in response to calcium ionReporter gene assaySPCC1322.03+ (wild type)wild_typeOverexpressionPECO:0000034PMID:21811607
FYPO:0001464increased immediate intracellular calcium spike following extracellular calcium stimulusSubstance quantificationSPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
FYPO:0001467normal increase in steady-state intracellular calcium level following extracellular calcium stimulusSubstance quantificationSPCC1322.03+ (wild type)wild_typeOverexpressionPMID:21811607
FYPO:0001470normal cell population growth on tacrolimusCell growth assaySPCC1322.03delta (deletion)deletionPECO:0000102, PECO:0000005PMID:21811607
FYPO:0001472normal cell population growth on tacrolimus during osmotic stressCell growth assaySPCC1322.03delta (deletion)deletionPECO:0000005, PECO:0000102, PECO:0000025PMID:21811607
FYPO:0001473resistance to tacrolimus during salt stressCell growth assaySPCC1322.03delta (deletion)deletionPECO:0000102, PECO:0000005PMID:21811607
FYPO:0002060viable vegetative cell populationMicroscopytrp1322delta (deletion)deletionPMID:20473289
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0022857transmembrane transporter activityISMPFAM:PF06011GO_REF:0000001
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0006810transportISMPFAM:PF06011GO_REF:0000001
GO:0055085transmembrane transportISMPFAM:PF06011GO_REF:0000024
GO:0060402calcium ion transport into cytosolIMPPMID:21811607
GO:1901198positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ionIMPPMID:21811607
GO:1901200negative regulation of calcium ion transport into cytosol involved in cellular response to salt stressIMPPMID:21811607
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0000139Golgi membraneIEASL-0134GO_REF:0000039
GO:0005737cytoplasmIDAPMID:16823372
GO:0005794Golgi apparatusIDAPMID:16823372
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
GO:0043231intracellular membrane-bounded organelleIDAPMID:21811607
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
112879031291811

References

Region Start End Reference
three_prime_UTR12907261291811PMID:21511999
three_prime_UTR12907261291811PMID:21511999
five_prime_UTR12879031288136PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF06011 IPR010308 Pfam TRP-like family 45 588 3
TMhelix TMHMM 63 85 955
TMhelix TMHMM 484 503 955
TMhelix TMHMM 187 209 955
TMhelix TMHMM 262 281 955
TMhelix TMHMM 458 480 955
TMhelix TMHMM 408 430 955
TMhelix TMHMM 320 351 955
TMhelix TMHMM 231 250 955
TMhelix TMHMM 371 393 955
TMhelix TMHMM 7 29 955
TMhelix TMHMM 546 568 955
SignalP-noTM signalp 1 25 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0000418signal_peptide
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 113.04 Da
Charge 15.00
Isoelectric point 8.77
Molecular weight 97.44 kDa
Number of residues 862
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.8PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.3PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Contact Curators
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
cis4cation diffusion family zinc membrane transporter Cis4 Dosage RescuePMID:22848669
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
apm1AP-1 adaptor complex mu subunit Apm1 Dosage RescuePMID:22848669
Contact Curators
External References
Database Identifier Description
NBRP SPCC1322.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1322.03 Retrieval of eukaryotic orthologs
BioGrid SPCC1322.03 BioGRID Interaction Datasets
Bähler Lab SPCC1322.03 Cell Cycle Expression Profile
Bähler Lab SPCC1322.03 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC1322.03 Pheromone response/mating expression profiles
Bähler Lab SPCC1322.03 Environmental stress expression profiles
Bähler Lab SPCC1322.03 Bähler Lab Transcriptome Viewer
Cyclebase SPCC1322.03 Cell Cycle Data
PInt SPCC1322.03 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC1322.03 Entrez Gene
EntrezGene2539071TRP-like ion channel
WikiGene2539071TRP-like ion channel
SPD / RIKEN38/38E06Orfeome Localization Data
UniProtKB/SwissProtO94543Uncharacterized membrane protein C1322.03
ModBaseO94543Database of comparative protein structure models
Pfam Protein DomainsO94543Pfam Domain Arrangement
RefSeq PeptideNP_588131TRP-like ion channel
RefSeq mRNANM_001023121972h- TRP-like ion channel (SPCC1322.03), mRNA
European Nucleotide ArchiveCAA22856ENA Protein Mapping
UniParcUPI000006B86AUniProt Archive

Literature for trp1322
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013