SPCC1450.09c

Gene Standard NameUnassigned ChromosomeIII
Systematic IDSPCC1450.09c Gene Start1745250
Synonyms Gene End1741202
Productphospholipase (predicted) Gene Length4049
Feature Typeprotein coding CDS Start1743459
Name Description CDS End1741588
Characterisation Statusbiological_role_inferred CDS Length1872

Ensembl Gene Location
  1. grx3
  2. dao1
  3. wtf16
  4. SPCC1450.09c
  5. SPNCRNA.1226
  6. SPNCRNA.501
  7. SPCC1450.10c
  8. cek1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPCC1450.09cdelta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004620phospholipase activityISSUniProtKB:P39105GO_REF:0000001
GO:0004622lysophospholipase activityIEAEC:3.1.1.5GO_REF:0000003
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0046475glycerophospholipid catabolic processICGO:0004620GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005576extracellular regionICGO:0009897GO_REF:0000001
GO:0005794Golgi apparatusIDAPMID:16823372
GO:0009277fungal-type cell wallISSUniProtKB:P39105GO_REF:0000001
GO:0009897external side of plasma membraneICGO:0009277GO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
117452501744097
217437621741202

References

Region Start End Reference
five_prime_UTR17437621743460PMID:21511999
three_prime_UTR17415871741202PMID:21511999
five_prime_UTR17452501744097PMID:21511999
three_prime_UTR17415871741202PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01735 IPR002642 Pfam Lysophospholipase, catalytic domain 125 606 6
SM00022 IPR002642 SMART Lysophospholipase, catalytic domain 48 601 6
PS51210 IPR002642 Prosite Profiles Lysophospholipase, catalytic domain 67 607 6
G3DSA:3.40.1090.10 Gene3D 67 567 8
SSF52151 IPR016035 SuperFamily 74 581 13
PTHR10728:SF2 hmmpanther 1 610 6
PTHR10728 hmmpanther 1 610 6
SignalP-noTM signalp 1 19 212

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.61 Da
Charge -31.00
Isoelectric point 4.08
Molecular weight 67.04 kDa
Number of residues 623
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide0.59PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.13PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
pit1serine/threonine protein kinase, meiotic Pit1 Negative GeneticPMID:22681890
SPAPB1A10.13sequence orphan Negative GeneticPMID:22681890
can1arginine transporter Can1 Negative GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
SPCC2H8.05csequence orphan Negative GeneticPMID:22681890
SPAC3H1.08cDUF1640 family protein Negative GeneticPMID:22681890
tdp1tyrosyl-DNA phosphodiesterase Tdp1 Negative GeneticPMID:22681890
rpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
zhf1zinc ion transporter Zhf1 Positive GeneticPMID:22681890
trx2mitochondrial thioredoxin Trx2 Negative GeneticPMID:22681890
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:22681890
SPCC132.03sequence orphan Negative GeneticPMID:22681890
ppr2mitochondrial PPR repeat protein Ppr2 Negative GeneticPMID:22681890
SPBC725.04oxalyl-CoA decarboxylase (predicted) Positive GeneticPMID:22681890
mug111sequence orphan Negative GeneticPMID:22681890
SPAC4D7.02cglycerophosphoryl diester phosphodiesterase (predicted) Negative GeneticPMID:22681890
rpl430260S ribosomal protein L37a (predicted) Negative GeneticPMID:22681890
whi5cell cycle transcriptional repressor Whi5 (predicted) Negative GeneticPMID:22681890
ppk8serine/threonine protein kinase Ppk8 (predicted) Positive GeneticPMID:22681890
SPCC1672.04cmitochondrial copper chaperone (predicted) Negative GeneticPMID:22681890
mug150sequence orphan Negative GeneticPMID:22681890
SPCC1827.03cacetyl-CoA ligase (predicted) Positive GeneticPMID:22681890
vps3CORVET complex subunit, GTPase regulator Vps3 (predicted) Negative GeneticPMID:22681890
vps901guanyl-nucleotide exchange factor Vps901 (predicted) Negative GeneticPMID:22681890
fus1formin Fus1 Negative GeneticPMID:22681890
ura3dihydroorotate dehydrogenase Ura3 Negative GeneticPMID:22681890
SPBC2G5.01ER protein involved in ER-nucleus signaling (predicted) Positive GeneticPMID:22681890
cys11cysteine synthase Negative GeneticPMID:22681890
SPBP16F5.05cribosome biogenesis protein Nop8 (predicted) Negative GeneticPMID:22681890
SPBC16H5.12cconserved fungal protein Negative GeneticPMID:22681890
atg14autophagy specific phophatidylinositol 3-kinase complex subunit Atg14 (predicted) Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPCC1450.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1450.09c Retrieval of eukaryotic orthologs
BioGrid SPCC1450.09c BioGRID Interaction Datasets
Bähler Lab SPCC1450.09c Cell Cycle Expression Profile
Bähler Lab SPCC1450.09c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC1450.09c Pheromone response/mating expression profiles
Bähler Lab SPCC1450.09c Environmental stress expression profiles
Bähler Lab SPCC1450.09c Bähler Lab Transcriptome Viewer
Cyclebase SPCC1450.09c Cell Cycle Data
PInt SPCC1450.09c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC1450.09c Entrez Gene
IntEnz3.1.1.5
WikiGene2539134phospholipase (predicted)
EntrezGene2539134phospholipase (predicted)
UniProtKB/SwissProtQ9Y7N6Putative lysophospholipase C1450.09c
ModBaseQ9Y7N6Database of comparative protein structure models
Pfam Protein DomainsQ9Y7N6Pfam Domain Arrangement
RefSeq PeptideNP_588308phospholipase (predicted)
RefSeq mRNANM_001023298972h- phospholipase (predicted) (SPCC1450.09c), mRNA
European Nucleotide ArchiveCAB40176ENA Protein Mapping
SPD / RIKEN27/27D10Orfeome Localization Data
UniParcUPI00001758D6UniProt Archive

Literature for SPCC1450.09c
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013