ppk33 (SPCC162.10)

Gene Standard Nameppk33 ChromosomeIII
Systematic IDSPCC162.10 Gene Start1561207
Synonyms Gene End1557811
Productserine/threonine protein kinase Ppk33 (predicted) Gene Length3397
Feature Typeprotein coding CDS Start1559240
Name Description CDS End1558224
Characterisation Statuspublished CDS Length1017

Ensembl Gene Location
  1. SPNCRNA.1204
  2. rsm1
  3. tco89
  4. SPCC162.11c
  5. ppk33
  6. SPNCRNA.1205
  7. SPNCRNA.495
  8. hmg1
  9. nup211
  10. SPNCRNA.1206
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000085sensitive to camptothecincompetitive growth assay evidenceppk33delta (deletion)deletionPMID:20537132
FYPO:0000266sensitive to DNA damaging agentscompetitive growth assay evidenceppk33delta (deletion)deletionPMID:20537132
FYPO:0002060viable vegetative cell populationMicroscopyppk33delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004674protein serine/threonine kinase activityISMPFAM:PF00069GO_REF:0000001
GO:0005524ATP bindingISMPFAM:PF00069GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006468protein phosphorylationISMPFAM:PF00069GO_REF:0000001
GO:0007165signal transductionNASGO_REF:0000051
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
115612071557811

References

Region Start End Reference
five_prime_UTR15612071559241PMID:21511999
three_prime_UTR15582231557811PMID:21511999
three_prime_UTR15582231557811PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00069 IPR000719 Pfam Protein kinase, catalytic domain 31 302 109
SM00220 IPR002290 SMART Serine/threonine- / dual specificity protein kinase, catalytic domain 30 302 74
PS50011 IPR000719 Prosite Profiles Protein kinase, catalytic domain 30 302 110
PS00108 IPR008271 Prosite Patterns Serine/threonine-protein kinase, active site 147 159 97
PS00107 IPR017441 Prosite Patterns Protein kinase, ATP binding site 36 59 73
G3DSA:3.30.200.20 Gene3D 25 95 108
G3DSA:1.10.510.10 Gene3D 96 312 111
SSF56112 IPR011009 SuperFamily 24 323 127
PTHR24356:SF0 hmmpanther 8 335 1
PTHR24356 hmmpanther 8 335 7

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.41 Da
Charge 21.00
Isoelectric point 9.99
Molecular weight 38.67 kDa
Number of residues 338
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.23PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.077PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
conserved in eukaryotes only
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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ppk16serine/threonine protein kinase Ppk16 (predicted) Positive GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
pyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
slx4structure-specific endonuclease subunit Slx4 Positive GeneticPMID:22681890
cds1replication checkpoint kinase Cds1 Negative GeneticPMID:22681890
atb2tubulin alpha 2 Positive GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Positive GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
mph1dual specificity protein kinase Mph1 Positive GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
rga2Rho-type GTPase activating protein Rga2 (predicted) Negative GeneticPMID:22681890
SPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
ubp2ubiquitin C-terminal hydrolase Ubp2 Negative GeneticPMID:22681890
mkh1MEK kinase (MEKK) Mkh1 Negative GeneticPMID:22681890
clr1cryptic loci regulator Clr1 Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
tas3RITS complex subunit 3 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPCC162.10 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC162.10 Retrieval of eukaryotic orthologs
BioGrid SPCC162.10 BioGRID Interaction Datasets
Bähler Lab SPCC162.10 Cell Cycle Expression Profile
Bähler Lab SPCC162.10 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC162.10 Pheromone response/mating expression profiles
Bähler Lab SPCC162.10 Environmental stress expression profiles
Bähler Lab SPCC162.10 Bähler Lab Transcriptome Viewer
Cyclebase SPCC162.10 Cell Cycle Data
PInt SPCC162.10 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC162.10 Entrez Gene
WikiGene2539202serine/threonine protein kinase Ppk33 (predicted)
Uniprot_genenamePPK33
EntrezGene2539202serine/threonine protein kinase Ppk33 (predicted)
SPD / RIKEN15/15B09Orfeome Localization Data
UniProtKB/SwissProtO74426Serine/threonine-protein kinase ppk33
ModBaseO74426Database of comparative protein structure models
Pfam Protein DomainsO74426Pfam Domain Arrangement
RefSeq PeptideNP_588234serine/threonine protein kinase Ppk33 (predicted)
RefSeq mRNANM_001023224972h- serine/threonine protein kinase Ppk33 (predicted) (ppk33), mRNA
European Nucleotide ArchiveCAA19590ENA Protein Mapping
UniParcUPI0000069FF8UniProt Archive

Literature for ppk33
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013