SPCC1620.05


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPCC1620.05 Feature Typeprotein coding
Synonyms Name Description
ProductRab geranylgeranyltransferase alpha subunit (predicted) Product Size344aa, 41.19 kDa
Genomic Location Chromosome III, 2152135-2157975 (5841nt); CDS:2152189-2153637 (1449nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
Rab geranylgeranyltransferase activity3
Annotation ExtensionEvidenceWith/FromReference
Rab GTPase binding8
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
cell division site305
Annotation ExtensionEvidenceWith/FromReference
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle pole body216
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
Rab-protein geranylgeranyltransferase complex2
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationSPCC1620.05ΔNull1438

Cell Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell, abnormal cell shape, normal cell sizeSPCC1620.05ΔNull199
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2152135..2152191, 2152234..2152344, 2152391..2152518, 2152561..2152748, 2152869..2153090, 2153164..2153367, 2153459..2157975
mRNA2152135..2157975
5' UTR2152135..2152188PMID:21511999
CDS2152189..2152191, 2152234..2152344, 2152391..2152518, 2152561..2152748, 2152869..2153090, 2153164..2153367, 2153459..2153637
3' UTR2153638..2157975PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01239 Pfam IPR002088 Protein prenyltransferase, alpha subunit 168 196 2
PF01239 Pfam IPR002088 Protein prenyltransferase, alpha subunit 129 157 2
PF01239 Pfam IPR002088 Protein prenyltransferase, alpha subunit 217 245 2
PF01239 Pfam IPR002088 Protein prenyltransferase, alpha subunit 92 121 2
PF01239 Pfam IPR002088 Protein prenyltransferase, alpha subunit 49 73 2
PS51147 Prosite Profiles IPR002088 Protein prenyltransferase, alpha subunit 44 78 2
PS51147 Prosite Profiles IPR002088 Protein prenyltransferase, alpha subunit 266 293 2
PS51147 Prosite Profiles IPR002088 Protein prenyltransferase, alpha subunit 125 159 2
PS51147 Prosite Profiles IPR002088 Protein prenyltransferase, alpha subunit 89 123 2
PS51147 Prosite Profiles IPR002088 Protein prenyltransferase, alpha subunit 165 199 2
PS51147 Prosite Profiles IPR002088 Protein prenyltransferase, alpha subunit 214 248 2
PTHR11129 HMMPANTHER 1 339 2
PTHR11129:SF2 HMMPANTHER 1 339 1
1.25.40.120 Gene3D 1 338 3
SSF48439 SuperFamily 1 338 2
Coil ncoils Rabaptin coiled-coil domain 6 39 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 119.75 Da
Charge 7.50
Isoelectric point 8.33
Molecular weight 41.19 kDa
Number of residues 344
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9008during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
8572during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
8368during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
9956during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
389.16during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
8131during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
1219.98during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.61during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Disease Association
DescriptionQualifierReferenceCount
cancer142
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPCC1620.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1620.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1620.05 BioGRID Interaction Datasets
Expression Viewer SPCC1620.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1620.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1620.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1620.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1620.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1620.05 Transcriptome Viewer (Bähler Lab)
GEO SPCC1620.05 GEO profiles
PInt SPCC1620.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1620.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1620.05 Fission yeast phenotypic data & analysis
Cyclebase SPCC1620.05.1 Cell Cycle Data
SPD / RIKEN44/44F11Orfeome Localization Data
UniProtKB/SwissProtO94412Geranylgeranyl transferase type-2 subunit alpha
ModBaseO94412Database of comparative protein structure models
STRINGO94412Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588463Rab geranylgeranyltransferase alpha subunit (predicted)
RefSeq mRNANM_001023454972h- Rab geranylgeranyltransferase alpha subunit (predicted) (SPCC1620.05), mRNA
European Nucleotide ArchiveCAA22489.1ENA Protein Mapping
UniParcUPI000006981CUniProt Archive

Literature for SPCC1620.05

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015