asp1 (SPCC1672.06c)

Gene Standard Nameasp1 ChromosomeIII
Systematic IDSPCC1672.06c Gene Start574562
Synonymsvip1 Gene End571470
Productinositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Gene Length3093
Feature Typeprotein coding CDS Start574472
Name Description CDS End571710
Characterisation Statuspublished CDS Length2763

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000021spheroid vegetative cellasp1delta (deletion)deletionPECO:0000004PMID:10388810
FYPO:0000247decreased cell population growth at high temperatureasp1delta (deletion)deletionPMID:10388810
FYPO:0002060viable vegetative cell populationMicroscopyasp1delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:10388810
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0000828inositol hexakisphosphate kinase activityISOSGD:S000004402GO_REF:0000024
GO:0000829inositol heptakisphosphate kinase activityISOSGD:S000004402GO_REF:0000024
GO:0000832inositol hexakisphosphate 5-kinase activityIEAEC:2.7.4.21GO_REF:0000003
GO:0003993acid phosphatase activityIEAIPR000560GO_REF:0000002
GO:0005524ATP bindingIEAUniProtKB:KW-0067GO_REF:0000037
GO:0016301kinase activityIEAUniProtKB:KW-0418GO_REF:0000037
GO:0033857diphosphoinositol-pentakisphosphate kinase activityIEAEC:2.7.4.24GO_REF:0000003
GO:0052723inositol hexakisphosphate 1-kinase activityIEAEC:2.7.4.21GO_REF:0000003
GO:0052724inositol hexakisphosphate 3-kinase activityIEAEC:2.7.4.21GO_REF:0000003
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0030866cortical actin cytoskeleton organizationIMPPMID:10388810
GO:0030950establishment or maintenance of actin cytoskeleton polarityIMPPMID:10388810
GO:0032958inositol phosphate biosynthetic processISOSGD:S000004402GO_REF:0000024
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005737cytoplasmISOSGD:S000004402GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
GO:0005856cytoskeletonIEASL-0090GO_REF:0000039
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1574562571470

References

Region Start End Reference
five_prime_UTR574562574473PMID:21511999
three_prime_UTR571709571470PMID:21511999
three_prime_UTR571709571470PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF08443 IPR013651 Pfam ATP-grasp fold, RimK-type 242 336 1
PF00328 IPR000560 Pfam Histidine phosphatase superfamily, clade-2 388 861 5
G3DSA:3.40.50.1240 Gene3D 387 420 15
G3DSA:3.40.50.1240 Gene3D 490 617 15
G3DSA:3.40.50.1240 Gene3D 733 871 15
G3DSA:3.40.50.1240 Gene3D 666 692 15
SSF53254 SuperFamily 731 871 15
SSF53254 SuperFamily 344 423 15
SSF53254 SuperFamily 598 682 15
SSF53254 SuperFamily 479 552 15
SSF56059 SuperFamily 214 337 11
PTHR12750 hmmpanther 3 913 1
PTHR12750:SF8 hmmpanther 3 913 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744
PMID:18257517

Protein Properties

Ave. residue weight 114.87 Da
Charge 12.50
Isoelectric point 7.73
Molecular weight 105.68 kDa
Number of residues 920
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide3914.91PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide3715.91PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide2.6PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide1.1PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:22681890
tea2kinesin-like protein Tea2 Phenotypic EnhancementPMID:20624911
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
sdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:22681890
mid1medial ring protein Mid1 Negative GeneticPMID:22681890
prp4serine/threonine protein kinase Prp4 Negative GeneticPMID:22681890
sep1forkhead transcription factor Sep1 Negative GeneticPMID:22681890
SPBPB10D8.02carylsulfatase (predicted) Negative GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
tip1CLIP170 family protein Tip1 Negative GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
ash2Ash2-trithorax family protein Negative GeneticPMID:22681890
mug28RNA-binding protein Mug28 Positive GeneticPMID:22681890
SPBC1861.04cRNA-binding protein Prp24 (predicted) Negative GeneticPMID:22681890
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
clr3histone deacetylase (class II) Clr3 Negative GeneticPMID:22681890
SPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
tsc1hamartin Negative GeneticPMID:22681890
spc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
pmk1MAP kinase Pmk1 Phenotypic EnhancementPMID:20624911
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
plb1phospholipase B homolog Plb1 Positive GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
sap114U2 snRNP subunit Sap114 Negative GeneticPMID:22681890
pzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
spn1septin Spn1 Phenotypic SuppressionPMID:23093943
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
uap2U2 snRNP-associated protein Uap2 Negative GeneticPMID:22681890
cdc10MBF transcription factor complex subunit Cdc10 Negative GeneticPMID:22681890
swd2Set1C complex subunit Swd2.1 Negative GeneticPMID:22681890
nup132nucleoporin Nup132 Negative GeneticPMID:22681890
cdr1NIM1 family serine/threonine protein kinase Cdr1/Nim1 Negative GeneticPMID:22681890
SPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:22681890
rxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
set3histone lysine methyltransferase Set3 Negative GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
nrm1negative regulator of MBF Negative GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
ubp3ubiquitin C-terminal hydrolase Ubp3 Phenotypic SuppressionPMID:19547744
pms1MutL family mismatch-repair protein Pms1 Negative GeneticPMID:22681890
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
hrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:22681890
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
tas3RITS complex subunit 3 Negative GeneticPMID:22681890
air1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:22681890
peg1CLASP family microtubule-associated protein Phenotypic EnhancementPMID:20624911
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
tsc2tuberin Negative GeneticPMID:22681890
hif2Set3 complex subunit Hif2 Negative GeneticPMID:22681890
cdc3profilin Synthetic RescuePMID:10388810
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
arp3actin-like protein Arp3 Dosage RescuePMID:10388810
Phenotypic EnhancementPMID:20624911
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:20624911
fft3fun thirty related protein Fft3 Negative GeneticPMID:22681890
SPAC17A5.09cprotein phosphatase regulatory subunit Glc9 (predicted) Negative GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
tcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:22681890
tea1cell end marker Tea1 Phenotypic EnhancementPMID:20624911
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
fic1C2 domain protein Fic1 Phenotypic SuppressionPMID:23093943
vps24ESCRT III complex subunit Vps24 Phenotypic SuppressionPMID:23093943
snt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
cdr2serine/threonine protein kinase Cdr2 Negative GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
ssm4dynactin microtubule-binding subunit, p150-Glued Ssm4 Negative GeneticPMID:22681890
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
pht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:19547744
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:22681890
arp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
rad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
rik1silencing protein Rik1 Negative GeneticPMID:22681890
prp1U4/U6 x U5 tri-snRNP complex subunit Prp1 Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
ubp2ubiquitin C-terminal hydrolase Ubp2 Positive GeneticPMID:22681890
SPBC725.05cnucleotide pyrophosphatase (predicted) Negative GeneticPMID:22681890
swi6HP1 family chromodomain protein Swi6 Negative GeneticPMID:22681890
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
mal3EB1 family Mal3 Phenotypic EnhancementPMID:20624911
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC1672.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1672.06c Retrieval of eukaryotic orthologs
BioGrid SPCC1672.06c BioGRID Interaction Datasets
Bähler Lab SPCC1672.06c Cell Cycle Expression Profile
Bähler Lab SPCC1672.06c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC1672.06c Pheromone response/mating expression profiles
Bähler Lab SPCC1672.06c Environmental stress expression profiles
Bähler Lab SPCC1672.06c Bähler Lab Transcriptome Viewer
Cyclebase SPCC1672.06c Cell Cycle Data
PInt SPCC1672.06c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC1672.06c Entrez Gene
SPD / RIKEN47/47B11Orfeome Localization Data
WikiGene2539244inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted)
Uniprot_genenameASP1
EntrezGene2539244inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted)
UniProtKB/SwissProtO74429Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
ModBaseO74429Database of comparative protein structure models
Pfam Protein DomainsO74429Pfam Domain Arrangement
RefSeq PeptideNP_587877inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted)
RefSeq mRNANM_001022869972h- inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) (asp1), mRNA
European Nucleotide ArchiveCAA20444ENA Protein Mapping
UniParcUPI000006C099UniProt Archive

Literature for asp1

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013