rpl1902 (SPCC1682.14)


Gene Standard Namerpl1902 Characterisation Statuspublished
Systematic IDSPCC1682.14 Feature Typeprotein coding
Synonymsrpl19-2 Name Description
Product60S ribosomal protein L19 Product Size193aa, 22.75 kDa
Genomic Location Chromosome III, 400721-401447 (727nt); CDS:400767-401348 (582nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation459
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to 5-fluorouracilrpl1902ΔNull271
viable vegetative cell populationrpl1902ΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyrpl1902ΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons400721..401447
mRNA400721..401447
5' UTR400721..400766PMID:21511999
CDS400767..401348
3' UTR401349..401447PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01280 Pfam IPR000196 Ribosomal protein L19/L19e domain 3 148 2
PTHR10722 HMMPANTHER 1 193 2
1vq8P01 Gene3D IPR015972 Ribosomal protein L19/L19e, domain 1 1 54 2
1vq8P03 Gene3D IPR015974 Ribosomal protein L19/L19e, domain 3 91 148 2
0037541 SuperFamily IPR000196 Ribosomal protein L19/L19e domain 3 143 2
Coil ncoils Rabaptin coiled-coil domain 144 165 968
MF_01475 hamap IPR027547 Ribosomal protein L19/L19e 3 149 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 117.89 Da
Charge 38.50
Isoelectric point 11.95
Molecular weight 22.75 kDa
Number of residues 193
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
24825during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
22883during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
24001during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
24652during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
23478during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
10422.82during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
7028.69during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
88during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
11during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycwf10U5 snRNP GTPase subunit Cwf10 Affinity Capture-MSPMID:24442611
affinity captured bylea1U2 snRNP-associated protein Lea1 (predicted) Affinity Capture-MSPMID:24442611
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withace2transcription factor Ace2 Negative GeneticPMID:22681890
negative genetic interaction withase1antiparallel microtubule cross-linking factor Ase1 Negative GeneticPMID:22681890
negative genetic interaction withcdk11serine/threonine protein kinase cdk11 Negative GeneticPMID:22681890
negative genetic interaction withcdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
negative genetic interaction withckb2CK2 family regulatory subunit Ckb2 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withcwf19complexed with Cdc5 protein Cwf19 Positive GeneticPMID:22681890
positive genetic interaction withdot2ESCRT II complex subunit Dot2 Positive GeneticPMID:22681890
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
positive genetic interaction withdsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:22681890
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withelp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:22681890
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withhri1eIF2 alpha kinase Hri1 Negative GeneticPMID:22681890
negative genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:22681890
negative genetic interaction withmed7mediator complex subunit Med7 Negative GeneticPMID:22681890
negative genetic interaction withmis4adherin, cohesin loading factor Mis4 Negative GeneticPMID:23050226
positive genetic interaction withmph1dual specificity protein kinase Mph1 Positive GeneticPMID:22681890
negative genetic interaction withmsn5karyopherin (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmst2histone acetyltransferase Mst2 Positive GeneticPMID:22681890
negative genetic interaction withnrm1MBF complex corepressor Nrm1 Negative GeneticPMID:22681890
negative genetic interaction withoca2serine/threonine protein kinase Oca2 Negative GeneticPMID:22681890
positive genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Positive GeneticPMID:22681890
negative genetic interaction withppk14serine/threonine protein kinase Ppk14 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withprz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
positive genetic interaction withpst2Clr6 histone deacetylase complex subunit Pst2 Positive GeneticPMID:22681890
negative genetic interaction withpub3HECT-type ubiquitin-protein ligase E3 Pub3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
negative genetic interaction withres1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
positive genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpb7DNA-directed RNA polymerase complex II subunit Rpb7 Positive GeneticPMID:22681890
positive genetic interaction withshg1Set1C complex subunit Shg1 Positive GeneticPMID:22681890
negative genetic interaction withskb1type II protein arginine N-methyltransferase Skb1 Negative GeneticPMID:22681890
negative genetic interaction withSPAC17H9.13cglutamate 5-kinase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC6F6.11cpyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
negative genetic interaction withSPBC21C3.03ABC1 kinase family protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Positive GeneticPMID:22681890
negative genetic interaction withsum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
positive genetic interaction withswc5Swr1 complex subunit Swc5 Positive GeneticPMID:22681890
positive genetic interaction withswd1Set1C complex subunit Swd1 Positive GeneticPMID:22681890
positive genetic interaction withswd2Set1C complex subunit Swd2.1 Positive GeneticPMID:22681890
positive genetic interaction withtfs1transcription elongation factor TFIIS Positive GeneticPMID:22681890
positive genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Positive GeneticPMID:22681890
positive genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC1682.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1682.14 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1682.14 BioGRID Interaction Datasets
Expression Viewer SPCC1682.14 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1682.14 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1682.14 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1682.14 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1682.14 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1682.14 Transcriptome Viewer (Bähler Lab)
GEO SPCC1682.14 GEO profiles
PInt SPCC1682.14 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1682.14 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1682.14 Fission yeast phenotypic data & analysis
Cyclebase SPCC1682.14.1 Cell Cycle Data
SPD / RIKEN06/06C10Orfeome Localization Data
UniProtKB/SwissProtO4269960S ribosomal protein L19-B
ModBaseO42699Database of comparative protein structure models
STRINGO42699Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_58780760S ribosomal protein L19
RefSeq mRNANM_001022800972h- 60S ribosomal protein L19 (rpl1902), mRNA
European Nucleotide ArchiveAB010048ENA EMBL mapping
European Nucleotide ArchiveCAA20680.1ENA Protein Mapping
UniParcUPI000006B1E7UniProt Archive

Literature for rpl1902

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015