mog1 (SPCC1840.01c)

Gene Standard Namemog1 Characterisation Statuspublished
Systematic IDSPCC1840.01c Feature Typeprotein coding
SynonymsSPCC790.04c Name Description
ProductRan GTPase binding protein Mog1 Product Size190aa, 20.88 kDa
Genomic Location Chromosome III, 2248273-2247361 (913nt); CDS:2248164-2247592 (573nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
Ran GTPase binding15
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
poly(A)+ mRNA export from nucleus17
Annotation ExtensionEvidenceWith/FromReference
protein import into nucleus21
Annotation ExtensionEvidenceWith/FromReference
small GTPase mediated signal transduction139
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationmog1ΔNull1428
unnamed (unrecorded)

Cell Phenotype

Term NameAlleleExpressionCount
abnormal mitotic cell cyclemog1ΔNull808
inviable after spore germination with elongated germ tubemog1ΔNull163
inviable after spore germination, single or double cell divisionmog1ΔNull101
normal RNA level during vegetative growth92
affecting rec8mog1-1Not specified
affecting mei4mog1-1Not specified
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04603 Pfam IPR007681 Ran-interacting Mog1 protein 1 146 1
PTHR15837:SF0 HMMPANTHER 2 190 1
PTHR15837 HMMPANTHER 2 190 1
3.40.1000.10 Gene3D IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich 2 190 1
SSF55724 SuperFamily IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich 2 190 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.92 Da
Charge -7.50
Isoelectric point 4.44
Molecular weight 20.88 kDa
Number of residues 190

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1670
present during mitotic M phaseS83
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S83 PMID:21712547
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
50446during GO:0000080PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
44556during GO:0000084PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
43867during GO:0000085PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
45399during GO:0000087PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
46393during GO:0072690PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
5123.01during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.8during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
0.8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3432
conserved in vertebrates3407
conserved in eukaryotes only2503

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturescid13poly(A) polymerase Cid13 Affinity Capture-WesternPMID:17651922
affinity capturesnxt2nuclear transport factor Nxt2 Affinity Capture-WesternPMID:17651922
affinity capturesspi1Ran GTPase Spi1 Affinity Capture-WesternPMID:17651922
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
synthetically rescued bycid13poly(A) polymerase Cid13 Synthetic RescuePMID:17651922
synthetically rescued bycrp79poly(A) binding protein Crp79 Synthetic RescuePMID:17651922
synthetically rescued bydef1RNAPII degradation factor Def1 (predicted) Synthetic RescuePMID:17651922
synthetically rescued bynxt2nuclear transport factor Nxt2 Synthetic RescuePMID:17651922
synthetically rescued byspi1Ran GTPase Spi1 Synthetic RescuePMID:17651922
rescued by overexpression ofspi1Ran GTPase Spi1 Dosage RescuePMID:11290708
synthetically rescued byssp1Ca2+/calmodulin-dependent (CaMMK)-like protein kinase Ssp1 Synthetic RescuePMID:17651922
External References
Database Identifier Description
NBRP SPCC1840.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1840.01c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1840.01c BioGRID Interaction Datasets
Expression Viewer SPCC1840.01c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1840.01c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1840.01c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1840.01c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1840.01c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1840.01c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1840.01c Cell Cycle Data
GEO SPCC1840.01c GEO profiles
PInt SPCC1840.01c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1840.01c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1840.01c Fission yeast phenotypic data & analysis
SPD / RIKEN06/06B04Orfeome Localization Data
UniProtKB/SwissProtO75002Nuclear import protein mog1
ModBaseO75002Database of comparative protein structure models
STRINGO75002Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588500Ran GTPase binding protein Mog1
RefSeq mRNANM_001023490972h- Ran GTPase binding protein Mog1 (mog1), mRNA
European Nucleotide ArchiveCAA21294.1ENA Protein Mapping
UniParcUPI0000069F90UniProt Archive

Literature for mog1

Search: Europe PMC or PubMed

Release Version: PomBase:25_49 - 02 Feb 2015