mog1 (SPCC1840.01c)


Gene Standard Namemog1 Characterisation Statuspublished
Systematic IDSPCC1840.01c Feature Typeprotein coding
SynonymsSPCC790.04c Name Description
ProductRan GTPase binding protein Mog1 Product Size190aa, 20.88 kDa
Genomic Location Chromosome III, 2248273-2247361 (913nt); CDS:2248164-2247592 (573nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0008536Ran GTPase bindingISOSGD:S000003835GO_REF:000002416
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0016973poly(A)+ mRNA export from nucleusIMPPMID:1129070817
GO:0006606protein import into nucleusISOSGD:S000003835GO_REF:000002413
GO:0007264small GTPase mediated signal transductionIGIspi1PMID:1129070858
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722317
GO:0005634nucleusIDAPMID:168233722730
predominantlyIDAPMID:11290708
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopymog1ΔNullPMID:204732891309
Microscopymog1ΔNullPECO:0000005, PECO:0000137PMID:23697806
no_namePMID:11290708

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000059abnormal mitotic cell cycleMicroscopymog1ΔNullPECO:0000005, PECO:0000137PMID:23697806564
FYPO:0000314inviable after spore germination with elongated germ tubeMicroscopymog1ΔNullPECO:0000005, PECO:0000137PMID:23697806162
FYPO:0001042inviable after spore germination, single or double cell divisionMicroscopymog1ΔNullPECO:0000005, PECO:0000137PMID:2369780691
FYPO:0001317normal RNA level during vegetative growthTranscript expression level evidencemog1-1Not specifiedPMID:2365822948
affecting mei4
affecting rec8Transcript expression level evidencemog1-1Not specifiedPMID:23658229
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
122482732247361

UTRs

Region Start End Reference
five_prime_UTR22482732248165PMID:21511999
three_prime_UTR22475912247361PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04603 Pfam IPR007681 Ran-interacting Mog1 protein 1 146 1
PTHR15837:SF0 HMMPANTHER 2 190 1
PTHR15837 HMMPANTHER 2 190 1
G3DSA:3.40.1000.10 Gene3D IPR016123 2 190 1
SSF55724 SuperFamily IPR016123 2 190 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.92 Da
Charge -7.50
Isoelectric point 4.44
Molecular weight 20.88 kDa
Number of residues 190
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
5123.01during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
2.8during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
spi1Ran GTPase Spi1 Dosage RescuePMID:11290708
nxt2nuclear transport factor Nxt2 Synthetic RescuePMID:17651922
ssp1serine/threonine protein kinase Ssp1 Synthetic RescuePMID:17651922
def1RNAPII degradation factor Def1 (predicted) Synthetic RescuePMID:17651922
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
spi1Ran GTPase Spi1 Affinity Capture-WesternPMID:17651922
nxt2nuclear transport factor Nxt2 Affinity Capture-WesternPMID:17651922
cid13poly(A) polymerase Cid13 Affinity Capture-WesternPMID:17651922
External References
Database Identifier Description
NBRP SPCC1840.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1840.01c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1840.01c BioGRID Interaction Datasets
Expression Viewer SPCC1840.01c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1840.01c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1840.01c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1840.01c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1840.01c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1840.01c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC1840.01c Cell Cycle Data
GEO SPCC1840.01c GEO profiles
PInt SPCC1840.01c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2539036Ran GTPase binding protein Mog1
EntrezGene2539036Ran GTPase binding protein Mog1
SPD / RIKEN06/06B04Orfeome Localization Data
UniProtKB/SwissProtO75002Nuclear import protein mog1
ModBaseO75002Database of comparative protein structure models
StringO75002Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588500Ran GTPase binding protein Mog1
RefSeq mRNANM_001023490972h- Ran GTPase binding protein Mog1 (mog1), mRNA
European Nucleotide ArchiveCAA21294ENA Protein Mapping
UniParcUPI0000069F90UniProt Archive

Literature for mog1

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014