mog1 (SPCC1840.01c)

Gene Standard Namemog1 ChromosomeIII
Systematic IDSPCC1840.01c Gene Start2248273
SynonymsSPCC790.04c Gene End2247361
ProductRan GTPase binding protein Mog1 Gene Length913
Feature Typeprotein coding CDS Start2248164
Name Description CDS End2247592
Characterisation Statuspublished CDS Length573

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001489inviable vegetative cellMicroscopymog1delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:11290708
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0008536Ran GTPase bindingISOSGD:S000003835GO_REF:0000024
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0006606protein import into nucleusISOSGD:S000003835GO_REF:0000024
GO:0007264small GTPase mediated signal transductionIGIspi1PMID:11290708
GO:0016973poly(A)+ mRNA export from nucleusIMPPMID:11290708
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
predominantlyIDAPMID:11290708
GO:0005829cytosolIDAPMID:16823372
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
122482732247361

References

Region Start End Reference
three_prime_UTR22475912247361PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF04603 IPR007681 Pfam Ran-interacting Mog1 protein 1 146 1
G3DSA:3.40.1000.10 IPR016123 Gene3D 2 190 1
SSF55724 IPR016124 SuperFamily 2 190 1
PTHR15837 hmmpanther 1 190 1
PTHR15837:SF0 hmmpanther 1 190 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.92 Da
Charge -7.50
Isoelectric point 4.44
Molecular weight 20.88 kDa
Number of residues 190
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide5123.01PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014
population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide0.8PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005
population_wide2.8PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
spi1Ran GTPase Spi1 Dosage RescuePMID:11290708
Synthetic RescuePMID:17651922
crp79poly(A) binding protein Crp79 Synthetic RescuePMID:17651922
def1RNAPII degradation factor Def1 (predicted) Synthetic RescuePMID:17651922
ssp1serine/threonine protein kinase Ssp1 Synthetic RescuePMID:17651922
nxt2nuclear transport factor Nxt2 Synthetic RescuePMID:17651922
cid13poly(A) polymerase Cid13 Synthetic RescuePMID:17651922
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
spi1Ran GTPase Spi1 Affinity Capture-WesternPMID:17651922
nxt2nuclear transport factor Nxt2 Affinity Capture-WesternPMID:17651922
cid13poly(A) polymerase Cid13 Affinity Capture-WesternPMID:17651922
External References
Database Identifier Description
NBRP SPCC1840.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1840.01c Retrieval of eukaryotic orthologs
BioGrid SPCC1840.01c BioGRID Interaction Datasets
Bähler Lab SPCC1840.01c Cell Cycle Expression Profile
Bähler Lab SPCC1840.01c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC1840.01c Pheromone response/mating expression profiles
Bähler Lab SPCC1840.01c Environmental stress expression profiles
Bähler Lab SPCC1840.01c Bähler Lab Transcriptome Viewer
Cyclebase SPCC1840.01c Cell Cycle Data
PInt SPCC1840.01c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC1840.01c Entrez Gene
SPD / RIKEN06/06B04Orfeome Localization Data
WikiGene2539036Ran GTPase binding protein Mog1
Uniprot_genenameMOG1
EntrezGene2539036Ran GTPase binding protein Mog1
UniProtKB/SwissProtO75002Nuclear import protein mog1
ModBaseO75002Database of comparative protein structure models
Pfam Protein DomainsO75002Pfam Domain Arrangement
RefSeq PeptideNP_588500Ran GTPase binding protein Mog1
RefSeq mRNANM_001023490972h- Ran GTPase binding protein Mog1 (mog1), mRNA
European Nucleotide ArchiveCAA21294ENA Protein Mapping
SPD / RIKEN06/06B04Orfeome Localization Data

Literature for mog1

Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013