amk2 (SPCC1919.03c)


Gene Standard Nameamk2 Characterisation Statuspublished
Systematic IDSPCC1919.03c Feature Typeprotein coding
Synonyms Name DescriptionAMpK subunit
ProductAMP-activated protein kinase beta subunit Amk2 Product Size298aa, 32.97 kDa
Genomic Location Chromosome III, 2209022-2207485 (1538nt); CDS:2208999-2207736 (1264nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding856
Annotation ExtensionEvidenceWith/FromReference
protein kinase regulator activity33
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process

GO Slim Terms

signaling


Term NameCount
cellular response to glucose starvation6
Annotation ExtensionEvidenceWith/FromReference
regulation of protein kinase activity59
Annotation ExtensionEvidenceWith/FromReference
signal transduction403
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
decreased cell population growth on glycerol/ethanol carbon sourceamk2ΔNull10
decreased conjugation frequencyamk2ΔNull44
decreased mating efficiencyamk2ΔNull252
viable vegetative cell populationamk2ΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
decreased sporulationamk2ΔNull71
viable vegetative cell with abnormal cell shapeamk2ΔNull478
viable vegetative cell with normal cell morphologyamk2ΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2209022..2208975, 2208921..2208661, 2208490..2208388, 2208291..2207823, 2207774..2207485
Introns2208974..2208922, 2208660..2208491, 2208387..2208292, 2207822..2207775
mRNA2209022..2207485
5' UTR2209022..2209000SPD138
CDS2208999..2208975, 2208921..2208661, 2208490..2208388, 2208291..2207823, 2207774..2207736
3' UTR2207735..2207485SPD138
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04739 Pfam IPR006828 Association with the SNF1 complex (ASC) domain 202 295 1
SM01010 SMART IPR006828 Association with the SNF1 complex (ASC) domain 201 296 1
PTHR10343:SF45 HMMPANTHER IPR030077 SNF1 protein kinase subunit beta-2/beta-3 18 294 1
PTHR10343 HMMPANTHER 18 294 1
SSF160219 SuperFamily 206 295 1
SSF81296 SuperFamily IPR014756 Immunoglobulin E-set 97 177 14

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.64 Da
Charge -1.00
Isoelectric point 6.31
Molecular weight 32.97 kDa
Number of residues 298
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS185, S191 1672
present during mitotic M phaseS185
present during mitotic M phaseS191
present during cellular response to thiabendazoleS55
Annotation ExtensionEvidenceResidueReference
present during cellular response to thiabendazole IDA S55 PMID:18257517
experimental evidence S185 PMID:24763107
present during mitotic M phase experimental evidence S185 PMID:21712547
experimental evidence S191 PMID:24763107
present during mitotic M phase experimental evidence S191 PMID:21712547
myristoylated residue 2
Annotation ExtensionEvidenceResidueReference
ISS PMID:12562756
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
37421during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
31745during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
27523during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
33382during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
20094.05during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
31279during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
7118.98during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.4during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.82during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Subunit Composition
DescriptionQualifierReferenceCount
heteromeric(6) PMID:172899423
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
cbs2AMP-activated protein kinase gamma subunit cbs2 Co-crystal or NMR structurePMID:17289942
affinity captured bycbs2AMP-activated protein kinase gamma subunit cbs2 Affinity Capture-MSPMID:19371376
affinity capturesssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Affinity Capture-WesternPMID:22375066
affinity captured byssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Affinity Capture-WesternPMID:22375066
ssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Co-crystal or NMR structurePMID:17289942
affinity captured byssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Affinity Capture-MSPMID:19371376
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withabc2glutathione S-conjugate-exporting ATPase Abc2 Positive GeneticPMID:22681890
positive genetic interaction withada1adenosine deaminase Ada1 Positive GeneticPMID:22681890
negative genetic interaction withago1argonaute Negative GeneticPMID:18818364
positive genetic interaction withalm1medial ring protein Alm1 Positive GeneticPMID:22681890
positive genetic interaction withalp14TOG/XMAP14 family protein Alp14 Positive GeneticPMID:18818364
positive genetic interaction withamt2ammonium transmembrane transporter Amt2 Positive GeneticPMID:22681890
positive genetic interaction witharg12argininosuccinate synthase Arg12 Positive GeneticPMID:22681890
positive genetic interaction witharp6actin-like protein Arp6 Positive GeneticPMID:18818364
positive genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Positive GeneticPMID:18818364
positive genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Positive GeneticPMID:22681890
positive genetic interaction withase1antiparallel microtubule cross-linking factor Ase1 Positive GeneticPMID:18818364
negative genetic interaction withash2Ash2-trithorax family protein Negative GeneticPMID:18818364
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
positive genetic interaction withatg11autophagy protein Atg11 Positive GeneticPMID:22681890
positive genetic interaction withatg1801WD repeat protein involved in autophagy Atg18a Positive GeneticPMID:22681890
positive genetic interaction withatg5autophagy associated protein Atg5 Positive GeneticPMID:22681890
positive genetic interaction withatl1alkyltransferase-like protein Atl1 Positive GeneticPMID:22681890
positive genetic interaction withbag102BAG family molecular chaperone regulator Bag102 Positive GeneticPMID:24497846
negative genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:18818364
positive genetic interaction withblt1ubiquitin domain-like protein Blt1 Positive GeneticPMID:22681890
negative genetic interaction withbop1ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withcbp1CENP-B homolog Positive GeneticPMID:18818364
negative genetic interaction withcho1phosphatidyl-N-methylethanolamine N-methyltransferase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withcia1histone chaperone Cia1 Negative GeneticPMID:18818364
negative genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:18818364
negative genetic interaction withcox19mitochondrial respiratory chain complex IV assembly protein Cox19 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withcpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Positive GeneticPMID:18818364
positive genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Positive GeneticPMID:18818364
negative genetic interaction withcsk1cyclin-dependent kinase/ cyclin-dependent kinase activating kinase Csk1 Negative GeneticPMID:22681890
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:18818364
negative genetic interaction withcsr102sec14 cytosolic factor family phosphatidylinositol transmembrane transporter (predicted) Negative GeneticPMID:22681890
positive genetic interaction withctu1cytosolic thiouridylase subunit Ctu1 Positive GeneticPMID:22681890
positive genetic interaction withctu2cytosolic thiouridylase subunit Ctu2 Positive GeneticPMID:22681890
negative genetic interaction withdbl2meiotic chromosome segregation protein Dbl2 Negative GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
negative genetic interaction withdcr1dicer Negative GeneticPMID:18818364
negative genetic interaction withdga1diacylglycerol O-acyltransferase Dga1 Negative GeneticPMID:22681890
positive genetic interaction withdph3diphthamide biosynthesis protein Dph3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withdsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:22681890
positive genetic interaction withecm29proteasome assembly chaperone Ecm29 Positive GeneticPMID:22681890
negative genetic interaction witheif21translation initiation factor eIF2A (predicted) Negative GeneticPMID:18818364
positive genetic interaction withelp1elongator subunit Elp1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withelp1elongator subunit Elp1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withelp6elongator complex subunit Elp6 (predicted) Positive GeneticPMID:18818364
positive genetic interaction witheme1Holliday junction resolvase subunit Eme1 Positive GeneticPMID:18818364
positive genetic interaction witheng1endo-1,3-beta-glucanase Eng1 Positive GeneticPMID:22681890
negative genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:18818364
positive genetic interaction witherf2palmitoyltransferase Erf2 Positive GeneticPMID:22681890
negative genetic interaction witherg5C-22 sterol desaturase Erg5 Negative GeneticPMID:22681890
negative genetic interaction withfbh1DNA helicase I, ubiquitin ligase F-box adaptor Fbh1 Negative GeneticPMID:18818364
positive genetic interaction withfcf2rRNA processing protein Fcf2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withftp105Ubp5 interacting protein Ftp105 Negative GeneticPMID:18818364
negative genetic interaction withftp105Ubp5 interacting protein Ftp105 Negative GeneticPMID:22681890
positive genetic interaction withgal1galactokinase Gal1 Positive GeneticPMID:22681890
negative genetic interaction withgcn20AAA family ATPase Gcn20 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withgim1prefoldin subunit 6, Gim1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withgit3G-protein coupled receptor Git3 Positive GeneticPMID:22681890
positive genetic interaction withgit5heterotrimeric G protein beta subunit Git5 Positive GeneticPMID:22681890
positive genetic interaction withgld1mitochondrial glycerol dehydrogenase Gld1 Positive GeneticPMID:22681890
positive genetic interaction withgmh5alpha-1,2-galactosyltransferase (predicted) Positive GeneticPMID:18818364
positive genetic interaction withgmh6alpha-1,2-galactosyltransferase Gmh6 Positive GeneticPMID:22681890
positive genetic interaction withgms1UDP-galactose transmembrane transporter Gms1 Positive GeneticPMID:22681890
negative genetic interaction withgsk3serine/threonine protein kinase Gsk3 Negative GeneticPMID:22681890
positive genetic interaction withgyp10GTPase activating protein Gyp10 Positive GeneticPMID:22681890
negative genetic interaction withhdd1HD domain protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withhhf2histone H4 h4.2 Positive GeneticPMID:22681890
negative genetic interaction withhif2Set3 complex subunit Hif2 Negative GeneticPMID:18818364
positive genetic interaction withhip4histone promoter control protein Hip4 Positive GeneticPMID:18818364
positive genetic interaction withhmo1HMG box protein Hmo1 Positive GeneticPMID:18818364
positive genetic interaction withhob3BAR adaptor protein Hob3 Positive GeneticPMID:22681890
negative genetic interaction withhos2histone deacetylase (class I) Hos2 Negative GeneticPMID:18818364
negative genetic interaction withhos2histone deacetylase (class I) Hos2 Negative GeneticPMID:22681890
negative genetic interaction withidp1isocitrate dehydrogenase Idp1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withlem2LEM domain protein Heh1/Lem2 Negative GeneticPMID:22681890
negative genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
negative genetic interaction withmac1membrane anchored protein Mac1 Negative GeneticPMID:22681890
positive genetic interaction withmad1mitotic spindle checkpoint protein Mad1 Positive GeneticPMID:18818364
negative genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
positive genetic interaction withmcp2RNA-binding protein Mcp2 Positive GeneticPMID:22681890
positive genetic interaction withmeu13Tat binding protein 1(TBP-1)-interacting protein (TBPIP) homolog (predicted) Positive GeneticPMID:18818364
positive genetic interaction withmga2IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Positive GeneticPMID:18818364
negative genetic interaction withmpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmrpl1mitochondrial ribosomal protein subunit L1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmtg1mitochondrial GTPase involved in translation Mtg1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmug122PX/PXA domain protein Positive GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:18818364
positive genetic interaction withmug20Schizosaccharomyces specific protein Mug20 Positive GeneticPMID:22681890
positive genetic interaction withmug57FAS1 domain protein Mug57 Positive GeneticPMID:22681890
negative genetic interaction withmug73plasma membrane transmembrane transport regulator (predicted) Negative GeneticPMID:22681890
positive genetic interaction withnap1nucleosome assembly protein Nap1 Positive GeneticPMID:18818364
negative genetic interaction withnde2mitochondrial NADH dehydrogenase (ubiquinone) Nde2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withnse6Smc5-6 complex non-SMC subunit Nse6 Positive GeneticPMID:22681890
negative genetic interaction withnup124nucleoporin Nup124 Negative GeneticPMID:22681890
negative genetic interaction withpar1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:18818364
negative genetic interaction withpds5mitotic cohesin-associated protein Pds5 Negative GeneticPMID:18818364
negative genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:18818364
positive genetic interaction withpfl4cell surface glycoprotein, adhesion molecule (predicted) Positive GeneticPMID:22681890
negative genetic interaction withpho24-nitrophenylphosphatase Negative GeneticPMID:18818364
negative genetic interaction withpho24-nitrophenylphosphatase Negative GeneticPMID:22681890
positive genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Positive GeneticPMID:22681890
negative genetic interaction withpmc3mediator complex subunit Pmc3/Med27 Negative GeneticPMID:18818364
negative genetic interaction withpof9F-box protein Pof9 Negative GeneticPMID:22681890
positive genetic interaction withppk30Ark1/Prk1 family protein kinase Ppk30 Positive GeneticPMID:18818364
negative genetic interaction withppk6serine/threonine protein kinase Ppk6 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppr2mitochondrial PPR repeat protein Ppr2 Negative GeneticPMID:22681890
negative genetic interaction withppr8mitochondrial PPR repeat protein Ppr8 Negative GeneticPMID:22681890
negative genetic interaction withptc3protein phosphatase 2c homolog 3 Negative GeneticPMID:22681890
positive genetic interaction withptr2PTR family peptide transmembrane transporter Ptr2 Positive GeneticPMID:22681890
positive genetic interaction withrad13DNA repair nuclease Rad13 Positive GeneticPMID:22681890
positive genetic interaction withrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Positive GeneticPMID:18818364
positive genetic interaction withrad55RecA family ATPase Rad55/Rhp55 Positive GeneticPMID:22681890
positive genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Positive GeneticPMID:18818364
positive genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Positive GeneticPMID:22681890
negative genetic interaction withrav2RAVE complex subunit Rav2 Negative GeneticPMID:22681890
positive genetic interaction withrds1conserved fungal protein Positive GeneticPMID:22681890
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:18818364
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:22681890
positive genetic interaction withrec11meiotic cohesin complex subunit Rec11 Positive GeneticPMID:22681890
negative genetic interaction withrec14Ski complex subunit Rec14 Negative GeneticPMID:18818364
positive genetic interaction withrga3Rho-type GTPase activating protein Rga3 Positive GeneticPMID:22681890
negative genetic interaction withrkr1RQC complex ubiquitin-protein ligase E3 Rkr1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:18818364
negative genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:22681890
negative genetic interaction withrog1acylglycerol lipase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrpl230160S ribosomal protein L23 Positive GeneticPMID:22681890
positive genetic interaction withrpl270160S ribosomal protein L27 Positive GeneticPMID:22681890
positive genetic interaction withrps10140S ribosomal protein S3a Positive GeneticPMID:22681890
positive genetic interaction withrtn1reticulon-like protein Rtn1 Positive GeneticPMID:22681890
negative genetic interaction withrud3Golgi matrix protein Rud3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsck1serine/threonine protein kinase Sck1 Negative GeneticPMID:22681890
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:18818364
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
negative genetic interaction withsds23PP2A-type phosphatase inhibitor Sds23/Moc1 Negative GeneticPMID:22681890
negative genetic interaction withsec28coatomer epsilon subunit (predicted) Negative GeneticPMID:18818364
negative genetic interaction withsec63ER protein translocation subcomplex subunit Sec63 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withsec72Sec7 domain protein, ARF GEF Sec72 Positive GeneticPMID:22681890
negative genetic interaction withser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withset1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
negative genetic interaction withset3histone lysine methyltransferase Set3 Negative GeneticPMID:18818364
positive genetic interaction withshk2PAK-related kinase Shk2 Positive GeneticPMID:18818364
negative genetic interaction withsnt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
positive genetic interaction withSPAC1071.09cDNAJ domain protein, DNAJC9 family (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC1093.03inositol polyphosphate phosphatase (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPAC11D3.03cconserved protein Positive GeneticPMID:22681890
negative genetic interaction withSPAC11D3.14c5-oxoprolinase (ATP-hydrolizing) (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC1296.01cphosphoacetylglucosamine mutase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC12G12.01cSEA complex subunit, ubiquitin-protein ligase E3 Positive GeneticPMID:18818364
positive genetic interaction withSPAC13A11.06pyruvate decarboxylase (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPAC1420.01cDUF1752 family protein, involved in regulation of transcription (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC15E1.02cDUF1761 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC17A2.14CorA family magnesium ion transmembrane transporter Positive GeneticPMID:22681890
positive genetic interaction withSPAC17H9.08mitochondrial coenzyme A transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC18G6.13Schizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC1A6.03cphospholipase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC22H10.09Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC29B12.13S-(hydroxymethyl)glutathione synthase activity (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC2C4.09mitochondrial calcium uniporter regulator (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC4H3.03cglucan 1,4-alpha-glucosidase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC694.04cconserved eukaryotic protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC926.06cleucine-rich repeat protein, unknown role Positive GeneticPMID:22681890
positive genetic interaction withSPAC977.02S. pombe specific 5Tm protein family Positive GeneticPMID:22681890
positive genetic interaction withSPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAPB1A10.05Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAPB21F2.02Dopey family protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAPB24D3.06cDUF1749 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC1271.14glutamate N-acetyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC15C4.06cubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC1604.03cconserved fungal protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC16G5.17transcription factor, zf-fungal binuclear cluster type (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:18818364
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
positive genetic interaction withSPBC1778.05chuman LAMTOR2 ortholog Positive GeneticPMID:22681890
positive genetic interaction withSPBC17D11.08WD repeat protein, DDB1 and CUL4-associated factor 7 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC1861.07elongin C (predicted) Negative GeneticPMID:18818364
positive genetic interaction withSPBC25B2.10Usp (universal stress protein) family protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC25H2.03vacuolar protein involved in phosphoinositide metabolism (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC28E12.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC29A10.16ccytochrome b5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
positive genetic interaction withSPBC354.04Schizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC354.08cDUF221 family protein Positive GeneticPMID:22681890
negative genetic interaction withSPBP35G2.14RNA-binding protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC1020.05phosphoprotein phosphatase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC584.11cSvf1 family protein Svf1 Positive GeneticPMID:22681890
positive genetic interaction withSPCC584.15carrestin/PY protein 2 Positive GeneticPMID:22681890
positive genetic interaction withSPCC594.01DUF1769 family protein Positive GeneticPMID:22681890
positive genetic interaction withSPCC622.02dubious Positive GeneticPMID:22681890
positive genetic interaction withSPCC736.02Schizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPCPB16A4.05curease accessory protein UREG (predicted) Positive GeneticPMID:22681890
negative genetic interaction withspf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:18818364
negative genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:18818364
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:18818364
negative genetic interaction withswd2Set1C complex subunit Swd2.1 Negative GeneticPMID:18818364
negative genetic interaction withswd3WD repeat protein Swd3 Negative GeneticPMID:18818364
positive genetic interaction withswi3replication fork protection complex subunit Swi3 Positive GeneticPMID:18818364
positive genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Positive GeneticPMID:22681890
positive genetic interaction withsyn1synaptotagmin family C2 domain protein, Syn1 Positive GeneticPMID:22681890
positive genetic interaction withtcg1single-stranded telomeric binding protein Tgc1 Positive GeneticPMID:22681890
positive genetic interaction withtco89TORC1 subunit Tco89 Positive GeneticPMID:22681890
negative genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtpp1trehalose-6-phosphate phosphatase Tpp1 Negative GeneticPMID:22681890
positive genetic interaction withtsc1hamartin Positive GeneticPMID:22681890
positive genetic interaction withubc16ubiquitin conjugating enzyme E2 Ubc16 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withubr11UBR ubiquitin-protein ligase E3 Ubr11 Positive GeneticPMID:18818364
positive genetic interaction withura3dihydroorotate dehydrogenase Ura3 Positive GeneticPMID:22681890
positive genetic interaction withura5orotate phosphoribosyltransferase Ura5 Positive GeneticPMID:22681890
positive genetic interaction withvht1vitamin H transmembrane transporter Vht1 Positive GeneticPMID:22681890
negative genetic interaction withvph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:18818364
positive genetic interaction withvps1301chorein homolog Vps13a (predicted) Positive GeneticPMID:22681890
positive genetic interaction withwos2p23 homolog, predicted co-chaperone Wos2 Positive GeneticPMID:22681890
positive genetic interaction withxks1xylulose kinase Xks1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative GeneticPMID:18818364
negative genetic interaction withymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withyox1MBF complex corepressor Yox1 Negative GeneticPMID:22681890
positive genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Positive GeneticPMID:18818364
positive genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Positive GeneticPMID:22681890
negative genetic interaction withzds1zds family protein phosphatase type A regulator Zds1 (predicted) Negative GeneticPMID:18818364
External References
Database Identifier Description
NBRP SPCC1919.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC1919.03c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC1919.03c BioGRID Interaction Datasets
Expression Viewer SPCC1919.03c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC1919.03c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC1919.03c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC1919.03c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC1919.03c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC1919.03c Transcriptome Viewer (Bähler Lab)
GEO SPCC1919.03c GEO profiles
PInt SPCC1919.03c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC1919.03c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC1919.03c Fission yeast phenotypic data & analysis
Cyclebase SPCC1919.03c.1 Cell Cycle Data
SPD / RIKEN20/20C01Orfeome Localization Data
UniProtKB/SwissProtP78789Uncharacterized protein C1919.03c
ModBaseP78789Database of comparative protein structure models
STRINGP78789Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588485AMP-activated protein kinase beta subunit Amk2
RefSeq mRNANM_001023476972h- AMP-activated protein kinase beta subunit Amk2 (amk2), mRNA
European Nucleotide ArchiveD89138ENA EMBL mapping
ePDB2OOXThe European PDB
PDB2OOXPDB
PDBsum2OOXPDBsum
ePDB2OOYThe European PDB
PDB2OOYPDB
PDBsum2OOYPDBsum
ePDB2QR1The European PDB
PDB2QR1PDB
PDBsum2QR1PDBsum
ePDB2QRCThe European PDB
PDB2QRCPDB
PDBsum2QRCPDBsum
ePDB2QRDThe European PDB
PDB2QRDPDB
PDBsum2QRDPDBsum
ePDB2QREThe European PDB
PDB2QREPDB
PDBsum2QREPDBsum
European Nucleotide ArchiveBAA87127.1ENA Protein Mapping
European Nucleotide ArchiveCAA22634.1ENA Protein Mapping
UniParcUPI000006C8D4UniProt Archive

Literature for amk2

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Release Version: PomBase:26_51 - 07 Apr 2015