SPCC23B6.04c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPCC23B6.04c Feature Typeprotein coding
Synonyms Name Description
Productsec14 cytosolic factor family (predicted) Product Size1008aa, 110.73 kDa
Genomic Location Chromosome III, 1280899-1277590 (3310nt); CDS:1280899-1277873 (3027nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0008526phosphatidylinositol transporter activityISOSGD:S000005175GO_REF:00000245
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006696ergosterol biosynthetic processISOSGD:S000005175GO_REF:000002439
GO:0015914phospholipid transportISOSGD:S000005175GO_REF:000002413
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005886plasma membraneIEAUniProtKB-KW:KW-1003GO_REF:0000037244
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPCC23B6.04cΔNullPECO:0000005, PECO:0000137PMID:236978063751
MicroscopySPCC23B6.04cΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001510viable vegetative cell, abnormal cell shape, normal cell size215
expressivity FYPO_EXT:0000003
penetrance FYPO_EXT:0000001
MicroscopySPCC23B6.04cΔNullPECO:0000137, PECO:0000005PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
112808991277590
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03765 Pfam IPR011074 CRAL/TRIO, N-terminal domain 597 659 4
PF00650 Pfam IPR001251 CRAL-TRIO domain 678 823 5
SM01100 SMART IPR011074 CRAL/TRIO, N-terminal domain 634 659 4
SM00516 SMART IPR001251 CRAL-TRIO domain 679 825 5
PS50191 Prosite Profiles IPR001251 CRAL-TRIO domain 675 828 5
PTHR10174 HMMPANTHER 565 901 5
PTHR10174:SF5 HMMPANTHER 565 901 1
3.40.525.10 Gene3D IPR001251 CRAL-TRIO domain 590 866 6
SSF52087 SuperFamily IPR001251 CRAL-TRIO domain 674 854 6
SSF46938 SuperFamily IPR011074 CRAL/TRIO, N-terminal domain 575 675 5
Coil ncoils Rabaptin coiled-coil domain 103 124 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.85 Da
Charge 9.00
Isoelectric point 7.19
Molecular weight 110.73 kDa
Number of residues 1008
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS934PMID:247631071670
present during mitotic M phaseexperimental evidenceS470PMID:21712547
experimental evidenceS909PMID:24763107
present during mitotic M phaseexperimental evidenceS294PMID:21712547
present during mitotic M phaseexperimental evidenceS246PMID:21712547
level fluctuates during mitotic cell cycleexperimental evidenceS543PMID:24763107
present during mitotic M phaseexperimental evidenceS559PMID:21712547
level fluctuates during mitotic cell cycleexperimental evidenceS914PMID:24763107
present during mitotic M phaseexperimental evidenceS497PMID:21712547
level fluctuates during mitotic cell cycleexperimental evidenceS183PMID:24763107
experimental evidenceS185PMID:24763107
present during mitotic M phaseexperimental evidenceS525PMID:21712547
present during mitotic M phaseexperimental evidenceS307PMID:21712547
present during cellular response to thiabendazoleIDAS543PMID:18257517
present during cellular response to thiabendazoleIDAS914PMID:18257517
present during cellular response to thiabendazoleIDAS525PMID:18257517
present during cellular response to thiabendazoleIDAS559PMID:18257517
present during mitotic M phaseexperimental evidenceS401PMID:21712547
level fluctuates during mitotic cell cycleexperimental evidenceS539PMID:24763107
present during mitotic M phaseexperimental evidenceS951PMID:21712547
present during mitotic M phaseexperimental evidenceS957PMID:21712547
present during mitotic M phaseexperimental evidenceS33PMID:21712547
present during mitotic M phaseexperimental evidenceS914PMID:21712547
present during mitotic M phaseexperimental evidenceS386PMID:21712547
present during mitotic M phaseexperimental evidenceS400PMID:21712547
present during mitotic M phaseexperimental evidenceS934PMID:21712547
present during mitotic M phaseexperimental evidenceS443PMID:21712547
present during mitotic M phaseexperimental evidenceS448PMID:21712547
present during mitotic M phaseexperimental evidenceS183PMID:21712547
present during mitotic M phaseexperimental evidenceS556PMID:21712547
present during mitotic M phaseexperimental evidenceS409PMID:21712547
present during mitotic M phaseexperimental evidenceS909PMID:21712547
present during mitotic M phaseexperimental evidenceS406PMID:21712547
present during mitotic M phaseexperimental evidenceS502PMID:21712547
experimental evidenceS485PMID:24763107
level fluctuates during mitotic cell cycleexperimental evidenceS525PMID:24763107
level fluctuates during mitotic cell cycleexperimental evidenceS306PMID:24763107
level fluctuates during mitotic cell cycleexperimental evidenceS72PMID:24763107
experimental evidenceS559PMID:24763107
present during mitotic M phaseexperimental evidenceS258PMID:21712547
present during mitotic M phaseexperimental evidenceS380PMID:21712547
present during mitotic M phaseexperimental evidenceS543PMID:21712547
present during mitotic M phaseexperimental evidenceS36PMID:21712547
present during mitotic M phaseexperimental evidenceS72PMID:21712547
present during mitotic M phaseexperimental evidenceS539PMID:21712547
present during mitotic M phaseexperimental evidenceS37PMID:21712547
present during mitotic M phaseexperimental evidenceS383PMID:21712547
present during mitotic M phaseexperimental evidenceS306PMID:21712547
present during mitotic M phaseexperimental evidenceS498PMID:21712547
MOD:00047O-phospho-L-threonineexperimental evidenceT44PMID:21712547690
present during mitotic M phase
present during mitotic M phaseexperimental evidenceT35PMID:21712547
present during mitotic M phaseexperimental evidenceT499PMID:21712547
present during mitotic M phaseexperimental evidenceT262PMID:21712547
experimental evidenceT44PMID:24763107
level fluctuates during mitotic cell cycleexperimental evidenceT449PMID:24763107
present during mitotic M phaseexperimental evidenceT540PMID:21712547
experimental evidenceT472PMID:24763107
present during mitotic M phaseexperimental evidenceT387PMID:21712547
present during mitotic M phaseexperimental evidenceT476PMID:21712547
present during mitotic M phaseexperimental evidenceT503PMID:21712547
present during mitotic M phaseexperimental evidenceT958PMID:21712547
present during mitotic M phaseexperimental evidenceT302PMID:21712547
present during mitotic M phaseexperimental evidenceT445PMID:21712547
present during mitotic M phaseexperimental evidenceT472PMID:21712547
present during mitotic M phaseexperimental evidenceT449PMID:21712547
present during mitotic M phaseexperimental evidenceT416PMID:21712547
MOD:00696phosphorylated residueNASPMID:182575171922
NASPMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
7959during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
7950during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
7726during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
8473during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
6025.62during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
8095during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
4334.79during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
8.7during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
1.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4599
conserved in eukaryotes4514
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
mis4adherin, cohesin loading factor Mis4 Negative GeneticPMID:23050226
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPCC23B6.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC23B6.04c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC23B6.04c BioGRID Interaction Datasets
Expression Viewer SPCC23B6.04c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC23B6.04c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC23B6.04c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC23B6.04c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC23B6.04c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC23B6.04c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC23B6.04c Cell Cycle Data
GEO SPCC23B6.04c GEO profiles
PInt SPCC23B6.04c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC23B6.04c Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN29/29H01Orfeome Localization Data
UniProtKB/SwissProtQ9UU99CRAL-TRIO domain-containing protein C23B6.04c
ModBaseQ9UU99Database of comparative protein structure models
STRINGQ9UU99Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588127sec14 cytosolic factor family (predicted)
RefSeq mRNANM_001023117972h- sec14 cytosolic factor family (predicted) (SPCC23B6.04c), mRNA
European Nucleotide ArchiveBAA87299.1ENA Protein Mapping
European Nucleotide ArchiveCAB51563.1ENA Protein Mapping
UniParcUPI000006A46DUniProt Archive

Literature for SPCC23B6.04c

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014