mft1 (SPCC24B10.11c)

Gene Standard Namemft1 ChromosomeIII
Systematic IDSPCC24B10.11c Gene Start921872
Synonyms Gene End920086
ProductTHO complex subunit 7 Mft1 (predicted) Gene Length1787
Feature Typeprotein coding CDS Start921221
Name Description CDS End920455
Characterisation Statusbiological_role_inferred CDS Length767

Ensembl Gene Location
  1. gad8
  2. ada2
  3. SPNCRNA.1161
  4. rps1702
  5. yta4
  6. mft1
  7. cgi121
  8. skb5
  9. snR94
  10. xlf1
  11. SPCTRNAARG.09
  12. SPRRNA.26
  13. SPNCRNA.475
  14. SPNCRNA.526
  15. SPCC24B10.15
  16. SPCC24B10.16c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopymft1delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006355regulation of transcription, DNA-dependentIEAUniProtKB:KW-0805GO_REF:0000037
GO:0006368transcription elongation from RNA polymerase II promoterISSUniProtKB:Q6I9Y2GO_REF:0000001
GO:0006406mRNA export from nucleusISSUniProtKB:Q6I9Y2GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000347THO complexISSUniProtKB:Q6I9Y2GO_REF:0000001
GO:0000445THO complex part of transcription export complexIEAIPR008501GO_REF:0000002
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1921872921215
2921161920943
3920886920736
4920686920086

References

Region Start End Reference
three_prime_UTR920454920086PMID:21511999
five_prime_UTR921872921222PMID:21511999
three_prime_UTR920454920086PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF05615 IPR008501 Pfam THO complex subunit 7/Mft1 3 129 1
Coil ncoils Rabaptin coiled-coil domain 79 107 974
Coil ncoils Rabaptin coiled-coil domain 121 149 974

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0001080coiled_coil

Protein Properties

Ave. residue weight 115.26 Da
Charge -12.00
Isoelectric point 4.48
Molecular weight 23.28 kDa
Number of residues 202
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide4415.66PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide937.03PMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide3.3PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.61PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Synthetic Growth DefectPMID:22965128
mtr4ATP-dependent RNA helicase, TRAMP complex subunit Mtr4 Synthetic Growth DefectPMID:22965128
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Co-localizationPMID:22965128
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External References
Database Identifier Description
NBRP SPCC24B10.11c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC24B10.11c Retrieval of eukaryotic orthologs
BioGrid SPCC24B10.11c BioGRID Interaction Datasets
Bähler Lab SPCC24B10.11c Cell Cycle Expression Profile
Bähler Lab SPCC24B10.11c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC24B10.11c Pheromone response/mating expression profiles
Bähler Lab SPCC24B10.11c Environmental stress expression profiles
Bähler Lab SPCC24B10.11c Bähler Lab Transcriptome Viewer
Cyclebase SPCC24B10.11c Cell Cycle Data
PInt SPCC24B10.11c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC24B10.11c Entrez Gene
WikiGene2539006THO complex subunit 7 (predicted)
EntrezGene2539006THO complex subunit 7 (predicted)
UniProtKB/SwissProtQ9P7J4Uncharacterized protein SPCC24B10.11c
ModBaseQ9P7J4Database of comparative protein structure models
Pfam Protein DomainsQ9P7J4Pfam Domain Arrangement
RefSeq PeptideNP_588014THO complex subunit 7 (predicted)
RefSeq mRNANM_001023005972h- THO complex subunit 7 (predicted) (SPCC24B10.11c), mRNA
European Nucleotide ArchiveCAB76220ENA Protein Mapping
SPD / RIKEN43/43B09Orfeome Localization Data
UniParcUPI000006BDC3UniProt Archive

Literature for mft1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013