SPCC24B10.16c


Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPCC24B10.16c Feature Typeprotein coding
Synonyms Name Description
Productproteasome assembly chaperone 4 (predicted) Product Size124aa, 13.50 kDa
Genomic Location Chromosome III, 930409-927629 (2781nt); CDS:930129-929755 (375nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
meiotic cell cycle240
Annotation ExtensionEvidenceWith/FromReference
proteasome assembly6
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2307
Annotation ExtensionEvidenceWith/FromReference
nucleus2691
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationSPCC24B10.16cΔ3819

Cell Phenotype

Term NameGenotypesCount
abnormal meiosisSPCC24B10.16cΔ119
viable vegetative cell with normal cell morphologySPCC24B10.16cΔ3097
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons930409..927629
mRNA930409..927629
5' UTR930409..930130PMID:21511999
CDS930129..929755
3' UTR929754..927629PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF16093 Pfam IPR032157 Proteasome assembly chaperone 4 19 93 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 108.85 Da
Charge -1.00
Isoelectric point 5.00
Molecular weight 13.50 kDa
Number of residues 124
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3507during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3235during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3096.35during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
2048during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.73during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.18during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999433
Taxonomic Conservation
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog600
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396
conserved in eukaryotes only2503
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load gene that interact geneitically with SPCC24B10.16c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withdad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
positive genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:22681890
positive genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Positive GeneticPMID:22681890
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withpst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:22681890
negative genetic interaction withhst2Sirtuin family histone deacetylase Hst2 Negative GeneticPMID:22681890
negative genetic interaction withubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Negative GeneticPMID:22681890
negative genetic interaction withpmc2mediator complex subunit Med1 Negative GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withnup60nucleoporin Nup60 Negative GeneticPMID:22681890
negative genetic interaction withcid12poly(A) polymerase Cid12 Negative GeneticPMID:22681890
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC24B10.16c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC24B10.16c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC24B10.16c BioGRID Interaction Datasets
Expression Viewer SPCC24B10.16c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC24B10.16c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC24B10.16c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC24B10.16c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC24B10.16c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC24B10.16c Transcriptome Viewer (Bähler Lab)
GEO SPCC24B10.16c GEO profiles
PInt SPCC24B10.16c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC24B10.16c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC24B10.16c Fission yeast phenotypic data & analysis
Cyclebase SPCC24B10.16c.1 Cell Cycle Data
SPD / RIKEN01/01H09Orfeome Localization Data
UniProtKB/SwissProtQ9P7J0Uncharacterized protein C24B10.16c
ModBaseQ9P7J0Database of comparative protein structure models
STRINGQ9P7J0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588019sequence orphan
RefSeq mRNANM_001023010972h- sequence orphan (SPCC24B10.16c), mRNA
European Nucleotide ArchiveCU329672ENA EMBL mapping
European Nucleotide ArchiveCAB76225ENA Protein Mapping
European Nucleotide ArchiveCAB76225.2ENA Protein Mapping
UniParcUPI000228F3F2UniProt Archive

Literature for SPCC24B10.16c

Search: Europe PMC or PubMed

Release Version: PomBase:29_56 - 12 Nov 2015