SPCC24B10.16c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPCC24B10.16c Feature Typeprotein coding
Synonyms Name Description
Productproteasome assembly chaperone 4 (predicted) Product Size124aa, 13.50 kDa
Genomic Location Chromosome III, 930409-927629 (2781nt); CDS:930129-929755 (375nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0051321meiotic cell cycleIEPPMID:12161753245
GO:0043248proteasome assemblyIGISPCC18.17cPMID:226818908
ISOUniProtKB:Q9BT73GO_REF:0000001
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0005634nucleusIDAPMID:168233722740
GO:0000502proteasome complexIGISPCC18.17cPMID:2268189043
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPCC24B10.16cΔNullPMID:204732893760
MicroscopySPCC24B10.16cΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000051abnormal meiosis83
expressivity FYPO_EXT:0000003microscopySPCC24B10.16cΔNullPMID:16169489
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001MicroscopySPCC24B10.16cΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1930409927629

UTRs

Region Coordinates Reference
five_prime_UTR930409..930130PMID:21511999
three_prime_UTR929754..927629PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count

View domain organization at Pfam

Protein Properties

Ave. residue weight 108.85 Da
Charge -1.00
Isoelectric point 5.00
Molecular weight 13.50 kDa
Number of residues 124
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3235during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
3096.35during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
2048during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
3507during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.73during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.18during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog580
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
not3CCR4-Not complex subunit Not3/5 (predicted) Positive GeneticPMID:22681890
pmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
ubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
fft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:22681890
nup60nucleoporin Nup60 Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Positive GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:22681890
cid12poly(A) polymerase Cid12 Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
hst2Sir2 family histone deacetylase Hst2 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC24B10.16c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC24B10.16c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC24B10.16c BioGRID Interaction Datasets
Expression Viewer SPCC24B10.16c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC24B10.16c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC24B10.16c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC24B10.16c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC24B10.16c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC24B10.16c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC24B10.16c Cell Cycle Data
GEO SPCC24B10.16c GEO profiles
PInt SPCC24B10.16c Protein-Protein Interaction Predictor (Bähler Lab)
SPD / RIKEN01/01H09Orfeome Localization Data
EntrezGene2539365sequence orphan
WikiGene2539365sequence orphan
UniProtKB/SwissProtQ9P7J0Uncharacterized protein C24B10.16c
ModBaseQ9P7J0Database of comparative protein structure models
STRINGQ9P7J0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588018PIN domain-containing protein
RefSeq PeptideNP_588019sequence orphan
RefSeq mRNANM_001023009972h- PIN domain-containing protein (SPCC24B10.15), mRNA
RefSeq mRNANM_001023010972h- sequence orphan (SPCC24B10.16c), mRNA
European Nucleotide ArchiveCAB76225ENA Protein Mapping
European Nucleotide ArchiveCAB76225.2ENA Protein Mapping
UniParcUPI000228F3F2UniProt Archive

Literature for SPCC24B10.16c

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014