emp24 (SPCC24B10.17)

Gene Standard Nameemp24 ChromosomeIII
Systematic IDSPCC24B10.17 Gene Start930468
Synonyms Gene End931984
ProductCOPII-coated vesicle component Emp24 (predicted) Gene Length1517
Feature Typeprotein coding CDS Start930591
Name Description CDS End931386
Characterisation Statusbiological_role_inferred CDS Length796

Ensembl Gene Location
  1. snR94
  2. xlf1
  3. SPCTRNAARG.09
  4. SPRRNA.26
  5. SPNCRNA.475
  6. SPNCRNA.526
  7. SPCC24B10.15
  8. SPCC24B10.16c
  9. emp24
  10. SPCC24B10.18
  11. SPCC24B10.19c
  12. SPCC24B10.20
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyemp24delta (deletion)deletionPMID:20473289
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0006886intracellular protein transportICGO:0030134GO_REF:0000001
GO:0006888ER to Golgi vesicle-mediated transportISOSGD:S000000005GO_REF:0000024
GO Cellular Component

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0000139Golgi membraneIEASL-0134GO_REF:0000039
GO:0005783endoplasmic reticulumIDAPMID:16823372
GO:0005789endoplasmic reticulum membraneIEASL-0097GO_REF:0000039
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
GO:0030134ER to Golgi transport vesicleISOSGD:S000000005GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1930468930684
2930751930947
3931078931984

References

Region Start End Reference
three_prime_UTR931387931984PMID:21511999
three_prime_UTR931387931984PMID:21511999
five_prime_UTR930468930590PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01105 IPR009038 Pfam GOLD 23 194 4
TMhelix TMHMM 167 189 955
TMhelix TMHMM 4 26 955
PS50866 IPR009038 Prosite Profiles GOLD 31 113 4
SSF101576 IPR009038 SuperFamily 29 119 3
PTHR22811:SF11 hmmpanther 9 199 1
PTHR22811 hmmpanther 9 199 4
SignalP-noTM signalp 1 21 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0000418signal_peptide
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 116.27 Da
Charge 3.50
Isoelectric point 7.57
Molecular weight 23.14 kDa
Number of residues 199
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide15244.68PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide4782.6PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.24PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.7PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
vps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
ago1argonaute Negative GeneticPMID:22681890
dcr1dicer Negative GeneticPMID:22681890
SPAC19B12.11czinc finger protein, human ZNF593 ortholog Negative GeneticPMID:22681890
msh2MutS protein homolog 2 Positive GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPCC24B10.17 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC24B10.17 Retrieval of eukaryotic orthologs
BioGrid SPCC24B10.17 BioGRID Interaction Datasets
Bähler Lab SPCC24B10.17 Cell Cycle Expression Profile
Bähler Lab SPCC24B10.17 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC24B10.17 Pheromone response/mating expression profiles
Bähler Lab SPCC24B10.17 Environmental stress expression profiles
Bähler Lab SPCC24B10.17 Bähler Lab Transcriptome Viewer
Cyclebase SPCC24B10.17 Cell Cycle Data
PInt SPCC24B10.17 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC24B10.17 Entrez Gene
SPD / RIKEN10/10A11Orfeome Localization Data
EntrezGene2539350COPII-coated vesicle component Emp24 (predicted)
Uniprot_genenameEMP24
WikiGene2539350COPII-coated vesicle component Emp24 (predicted)
UniProtKB/SwissProtQ9P7I9Endosomal protein P24B
ModBaseQ9P7I9Database of comparative protein structure models
Pfam Protein DomainsQ9P7I9Pfam Domain Arrangement
RefSeq PeptideNP_588020COPII-coated vesicle component Emp24 (predicted)
RefSeq mRNANM_001023011972h- COPII-coated vesicle component Emp24 (predicted) (emp24), mRNA
European Nucleotide ArchiveCAB76226ENA Protein Mapping
UniParcUPI000006C6C7UniProt Archive

Literature for emp24
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013