emp24 (SPCC24B10.17)

Gene Standard Nameemp24 Characterisation Statusbiological_role_inferred
Systematic IDSPCC24B10.17 Feature Typeprotein coding
Synonyms Name Description
ProductCOPII-coated vesicle component Emp24 (predicted) Product Size199aa, 23.14 kDa
Genomic Location Chromosome III, 930468-931984 (1517nt); CDS:930591-931386 (796nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006888ER to Golgi vesicle-mediated transportISOSGD:S000000005GO_REF:000002475
GO:0006886intracellular protein transportICGO:0030134GO_REF:0000001332
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030134ER to Golgi transport vesicleISOSGD:S000000005GO_REF:000002425
GO:0005794Golgi apparatusIEAUniProtKB-KW:KW-0333GO_REF:0000037355
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyemp24ΔNullPECO:0000005, PECO:0000137PMID:236978063755

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopyemp24ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01105 Pfam IPR009038 GOLD 23 194 4
TMhelix TMHMM 4 26 959
TMhelix TMHMM 167 189 959
PS50866 Prosite Profiles IPR009038 GOLD 31 113 4
PTHR22811:SF11 HMMPANTHER 1 199 1
PTHR22811 HMMPANTHER 1 199 4
SSF101576 SuperFamily IPR009038 29 119 3
SignalP-noTM signalp 1 21 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 116.27 Da
Charge 3.50
Isoelectric point 7.57
Molecular weight 23.14 kDa
Number of residues 199
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
15244.68during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
4782.6during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.7during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.24during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
msh2MutS protein homolog 2 Positive GeneticPMID:22681890
vps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
ago1argonaute Negative GeneticPMID:22681890
dcr1dicer Negative GeneticPMID:22681890
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
SPAC19B12.11czinc finger protein, human ZNF593 ortholog Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC24B10.17 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC24B10.17 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC24B10.17 BioGRID Interaction Datasets
Expression Viewer SPCC24B10.17 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC24B10.17 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC24B10.17 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC24B10.17 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC24B10.17 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC24B10.17 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC24B10.17 Cell Cycle Data
GEO SPCC24B10.17 GEO profiles
PInt SPCC24B10.17 Protein-Protein Interaction Predictor (Bähler Lab)
SPD / RIKEN10/10A11Orfeome Localization Data
EntrezGene2539350COPII-coated vesicle component Emp24 (predicted)
WikiGene2539350COPII-coated vesicle component Emp24 (predicted)
UniProtKB/SwissProtQ9P7I9Endosomal protein P24B
ModBaseQ9P7I9Database of comparative protein structure models
StringQ9P7I9Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588020COPII-coated vesicle component Emp24 (predicted)
RefSeq mRNANM_001023011972h- COPII-coated vesicle component Emp24 (predicted) (emp24), mRNA
European Nucleotide ArchiveCAB76226ENA Protein Mapping
UniParcUPI000006C6C7UniProt Archive

Literature for emp24

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014