SPCC285.05


Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPCC285.05 Feature Typeprotein coding
Synonyms Name Description
Productpurine nucleoside transmembrane transporter (predicted) Product Size348aa, 38.14 kDa
Genomic Location Chromosome III, 1802086-1804181 (2096nt); CDS:1802662-1803708 (1047nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
purine nucleoside transmembrane transporter activity6
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
purine nucleoside transmembrane transport6
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum596
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane963
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationSPCC285.05Δ3837

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPCC285.05Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1802086..1804181
5' UTR1802086..1802661PMID:21511999
3' UTR1803709..1804181PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06516 Pfam IPR009486 Purine nucleoside permease 31 347 1
TMhelix TMHMM 2 24 953
PTHR38643 HMMPANTHER 1 347 1
3.40.50.1580 Gene3D IPR000845 Nucleoside phosphorylase domain 33 222 3
PIRSF013171 PIRSF IPR009486 Purine nucleoside permease 3 348 1
SignalP-noTM signalp 1 21 207

View domain organization at Pfam

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279

Protein Properties

Ave. residue weight 109.60 Da
Charge -10.00
Codon Adaptation Index 0.46
Isoelectric point 4.56
Molecular weight 38.14 kDa
Number of residues 348
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPCC285.05

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9513.25during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
56473.28during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5.5during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
4.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog601
conserved in fungi only618
conserved in fungi4605
conserved in eukaryotes4515
Orthologs

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPCC285.05 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withusp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
negative genetic interaction withtip41TIP41-like type 2a phosphatase regulator Tip41 Negative GeneticPMID:22681890
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
negative genetic interaction withsap114U2 snRNP subunit Sap114 Negative GeneticPMID:22681890
negative genetic interaction withclr1SHREC complex subunit Clr1 Negative GeneticPMID:22681890
negative genetic interaction withpek1MAP kinase kinase Pek1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC285.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC285.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC285.05 BioGRID Interaction Datasets
Expression Viewer SPCC285.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC285.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC285.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC285.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC285.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC285.05 Transcriptome Viewer (Bähler Lab)
GEO SPCC285.05 GEO profiles
PInt SPCC285.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC285.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC285.05 Fission yeast phenotypic data & analysis
Cyclebase SPCC285.05.1 Cell Cycle Data
SPD / RIKEN16/16A02Orfeome Localization Data
UniProtKB/SwissProtO74493Probable purine nucleoside permease C285.05
ModBaseO74493Database of comparative protein structure models
STRINGO74493Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588334purine nucleoside transmembrane transporter (predicted)
RefSeq mRNANM_001023325972h- purine nucleoside transmembrane transporter (predicted) (SPCC285.05), mRNA

Literature for SPCC285.05

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016