SPCC285.05


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPCC285.05 Feature Typeprotein coding
Synonyms Name Description
Productpurine nucleoside transmembrane transporter (predicted) Product Size348aa, 38.14 kDa
Genomic Location Chromosome III, 1802086-1804181 (2096nt); CDS:1802662-1803708 (1047nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015211purine nucleoside transmembrane transporter activityISMPFAM:PF06516GO_REF:00000015
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015860purine nucleoside transmembrane transportISMPFAM:PF06516GO_REF:00000245
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372593
GO:0016021integral component of membraneICGO:0015211GO_REF:00000011017
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPCC285.05ΔNullPMID:204732893730
MicroscopySPCC285.05ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001MicroscopySPCC285.05ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
118020861804181

UTRs

Region Coordinates Reference
five_prime_UTR1802086..1802661PMID:21511999
three_prime_UTR1803709..1804181PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06516 Pfam IPR009486 Purine nucleoside permease 31 347 1
TMhelix TMHMM 2 24 959
3.40.50.1580 Gene3D IPR000845 Nucleoside phosphorylase domain 33 222 3
PIRSF013171 PIRSF IPR009486 Purine nucleoside permease 1 348 1
SignalP-noTM signalp 1 21 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide278

Protein Properties

Ave. residue weight 109.60 Da
Charge -10.00
Isoelectric point 4.56
Molecular weight 38.14 kDa
Number of residues 348
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
9513.25during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
56473.28during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
5.5during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
4.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog579
conserved in fungi only603
conserved in fungi4569
conserved in eukaryotes4482
Orthologs

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
clr1cryptic loci regulator Clr1 Negative GeneticPMID:22681890
sap114U2 snRNP subunit Sap114 Negative GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
tip41TIP41-like type 2a phosphatase regulator Tip41 Negative GeneticPMID:22681890
pek1MAP kinase kinase Pek1 Negative GeneticPMID:22681890
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
External References
Database Identifier Description
NBRP SPCC285.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC285.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC285.05 BioGRID Interaction Datasets
Expression Viewer SPCC285.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC285.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC285.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC285.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC285.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC285.05 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC285.05 Cell Cycle Data
GEO SPCC285.05 GEO profiles
PInt SPCC285.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC285.05 Peptides identified in tandem mass spectrometry proteomics experiments
EntrezGene2539334purine nucleoside transporter (predicted)
WikiGene2539334purine nucleoside transporter (predicted)
SPD / RIKEN16/16A02Orfeome Localization Data
UniProtKB/SwissProtO74493Uncharacterized protein C285.05
ModBaseO74493Database of comparative protein structure models
STRINGO74493Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588334purine nucleoside transporter (predicted)
RefSeq mRNANM_001023325972h- purine nucleoside transporter (predicted) (SPCC285.05), mRNA
European Nucleotide ArchiveCAA20844ENA Protein Mapping
European Nucleotide ArchiveCAA20844.1ENA Protein Mapping
UniParcUPI0000069C5EUniProt Archive

Literature for SPCC285.05

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014