set1 (SPCC306.04c)


Gene Standard Nameset1 Characterisation Statuspublished
Systematic IDSPCC306.04c Feature Typeprotein coding
Synonymskmt2 Name Description
Producthistone lysine methyltransferase Set1 Product Size920aa, 105.04 kDa
Genomic Location Chromosome III, 416039-412293 (3747nt); CDS:415527-412765 (2763nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
histone methyltransferase activity (H3-K4 specific)1
Annotation ExtensionEvidenceWith/FromReference
histone-lysine N-methyltransferase activity8
Annotation ExtensionEvidenceWith/FromReference
RNA binding571
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
heterochromatin assembly involved in chromatin silencing17
Annotation ExtensionEvidenceWith/FromReference
histone H3-K4 methylation17
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytoplasm4209
Annotation ExtensionEvidenceWith/FromReference
nuclear chromatin318
Annotation ExtensionEvidenceWith/FromReference
Set1C/COMPASS complex8
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
increased number of cells with 1C DNA contentset1ΔNull40
normal growth during cellular response to UVset1::Kan (disruption)Null56
normal growth on hydroxyureaset1::Kan (disruption)Null42
sensitive to 5-fluorouracilset1ΔNull271
sensitive to bleomycinset1ΔNull75
sensitive to hydroxyureaset1ΔNull534
sensitive to methyl methanesulfonateset1ΔNull239
sensitive to thiabendazoleset1ΔNull219
viable vegetative cell populationset1::Kan (disruption)Null3809
set1ΔNull

Cell Phenotype

Term NameAlleleExpressionCount
abnormal histone H3-K4 methylationset1ΔNull9
abnormal microtubule cytoskeleton morphology during mitotic interphaseset1ΔNull186
abnormal mitotic cell cycleset1ΔNull834
abnormal mitotic cell cycle arrest with unreplicated DNAset1ΔNull50
abolished histone H3-K4 dimethylationset1ΔNull1
abolished histone H3-K4 methylationset1ΔNull6
abolished histone H3-K4 trimethylationset1ΔNull2
abolished histone methyltransferase activity (H3-K4 specific)set1::Kan (disruption)Null1
decreased chromatin silencing at centromereset1::Kan (disruption)Null40
decreased chromatin silencing at telomereset1::Kan (disruption)Null25
decreased histone H3-K4 trimethylationset1ΔNull2
elongated telomeresset1::Kan (disruption)Null169
increased protein localization to heterochromatin at centromere outer repeat2
affecting rpb1set1ΔNull
normal cell cycle regulation during cellular response to ionizing radiationset1::Kan (disruption)Null11
normal centromeric outer repeat transcript-derived siRNA levelset1ΔNull8
normal genetic imprinting at mating-type locusset1ΔNull6
normal mRNA level during vegetative growth12
affecting rad51set1::Kan (disruption)Null
affecting suc22set1::Kan (disruption)Null
viable elongated vegetative cellset1ΔNull301
viable vegetative cell with abnormal cell shapeset1ΔNull482
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons416039..412293
mRNA416039..412293
5' UTR416039..415528PMID:21511999
CDS415527..412765
3' UTR412764..412293PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11764 Pfam IPR024657 COMPASS complex Set1 subunit, N-SET domain 630 771 1
PF00856 Pfam IPR001214 SET domain 794 897 12
PF00076 Pfam IPR000504 RNA recognition motif domain 96 172 61
PF11767 Pfam IPR024636 Histone lysine methyltransferase SET associated 279 343 1
SM00360 SMART IPR000504 RNA recognition motif domain 95 175 68
SM00360 SMART IPR000504 RNA recognition motif domain 276 343 68
SM00508 SMART IPR003616 Post-SET domain 904 920 3
SM00317 SMART IPR001214 SET domain 781 904 11
PS50280 Prosite Profiles IPR001214 SET domain 781 898 13
PS50868 Prosite Profiles IPR003616 Post-SET domain 904 920 3
PS51572 Prosite Profiles IPR017111 Histone H3-K4 methyltransferase Set1, fungal 6 920 1
PS50102 Prosite Profiles IPR000504 RNA recognition motif domain 94 179 72
PTHR22884 HMMPANTHER 1 920 3
PTHR22884:SF281 HMMPANTHER 1 920 1
3.30.70.330 Gene3D IPR012677 Nucleotide-binding alpha-beta plait domain 78 179 83
3.30.70.330 Gene3D IPR012677 Nucleotide-binding alpha-beta plait domain 289 355 83
2.170.270.10 Gene3D 777 919 8
SSF54928 SuperFamily 78 180 78
SSF54928 SuperFamily 289 351 78
SSF82199 SuperFamily 777 917 13
PIRSF037104 PIRSF IPR017111 Histone H3-K4 methyltransferase Set1, fungal 1 920 1
Coil ncoils Rabaptin coiled-coil domain 191 212 968

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000302rrm RNA recognition motifTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000302
PBO:0001327SET domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001327

Protein Properties

Ave. residue weight 114.17 Da
Charge 25.50
Isoelectric point 9.26
Molecular weight 105.04 kDa
Number of residues 920
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS534
present during mitotic M phaseS593
present during mitotic M phaseS531
S531, S534
Annotation ExtensionEvidenceResidueReference
experimental evidence S531 PMID:24763107
present during mitotic M phase experimental evidence S531 PMID:21712547
experimental evidence S534 PMID:24763107
present during mitotic M phase experimental evidence S534 PMID:21712547
present during mitotic M phase experimental evidence S593 PMID:21712547
O-phospho-L-threonineT533 698
Annotation ExtensionEvidenceResidueReference
experimental evidence T533 PMID:24763107
phosphorylated residue 1927
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
175.5during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
574during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.61during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Misc
DescriptionQualifierReferenceCount
Set1 mediated H3 K4 methylation is preferentially enriched at euchromatic loci PMID:121936581
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byash2Ash2-trithorax family protein Affinity Capture-MSPMID:14617822
affinity capturesash2Ash2-trithorax family protein Affinity Capture-MSPMID:14617822
modifieshht3histone H3 h3.3 Biochemical ActivityPMID:12589755
affinity captured bysdc1Dpy-30 domain protein Sdc1 Affinity Capture-MSPMID:14617822
affinity capturessdc1Dpy-30 domain protein Sdc1 Affinity Capture-MSPMID:14617822
affinity capturesset1histone lysine methyltransferase Set1 Affinity Capture-MSPMID:14617822
affinity capturesshg1Set1C complex subunit Shg1 Affinity Capture-MSPMID:14617822
affinity capturesspf1Set1C PHD Finger protein Spf1 Affinity Capture-MSPMID:14617822
affinity captured byspf1Set1C PHD Finger protein Spf1 Affinity Capture-MSPMID:14617822
affinity capturesswd1Set1C complex subunit Swd1 Affinity Capture-MSPMID:14617822
affinity captured byswd1Set1C complex subunit Swd1 Affinity Capture-MSPMID:14617822
affinity capturesswd2Set1C complex subunit Swd2.1 Affinity Capture-MSPMID:14617822
affinity captured byswd2Set1C complex subunit Swd2.1 Affinity Capture-MSPMID:14617822
affinity captured byswd3WD repeat protein Swd3 Affinity Capture-MSPMID:14617822
affinity capturesswd3WD repeat protein Swd3 Affinity Capture-MSPMID:14617822
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withacp2F-actin capping protein beta subunit Acp2 Positive GeneticPMID:22681890
negative genetic interaction withada1adenosine deaminase Ada1 Negative GeneticPMID:22681890
positive genetic interaction withadh8alcohol dehydrogenase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
negative genetic interaction withalg10dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase Alg10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withalg12dolichyl pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase Alg12 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withalg5dolichyl-phosphate beta-glucosyltransferase Alg5 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withalm1medial ring protein Alm1 Positive GeneticPMID:22681890
positive genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Positive GeneticPMID:22681890
negative genetic interaction withalp14TOG/XMAP14 family protein Alp14 Negative GeneticPMID:18818364
negative genetic interaction withamk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:18818364
negative genetic interaction withapm4AP-2 adaptor complex subunit Apm4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withare2acyl-coA-sterol acyltransferase Are2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:18818364
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
positive genetic interaction withasc1cofactor for cytoplasmic methionyl-and glutamyl-tRNA synthetases Asc1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withash2Ash2-trithorax family protein Positive GeneticPMID:18818364
positive genetic interaction withash2Ash2-trithorax family protein Positive GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
negative genetic interaction withasl1cell wall protein Asl1, predicted O-glucosyl hydrolase Negative GeneticPMID:22681890
positive genetic interaction withatg9autophagy associated protein Atg9 Positive GeneticPMID:22681890
positive genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatp12mitochondrial F1-ATPase chaperone Atp12 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatp15F0-ATPase epsilon subunit (predicted) Positive GeneticPMID:22681890
positive genetic interaction withayr11-acyldihydroxyacetone phosphate reductase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:18818364
negative genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:22681890
positive genetic interaction withbob1prefoldin subunit 5 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withcay1cactin, spliceosome complex subunit Negative GeneticPMID:18818364
positive genetic interaction withcbf12CBF1/Su(H)/LAG-1 family transcription factor Cbf12 Positive GeneticPMID:22681890
enhances phenotype ofcbp1CENP-B homolog Phenotypic EnhancementPMID:22907751
positive genetic interaction withcbp1CENP-B homolog Positive GeneticPMID:18818364
negative genetic interaction withcbs2AMP-activated protein kinase gamma subunit cbs2 Negative GeneticPMID:18818364
negative genetic interaction withcch1calcium ion channel Cch1 Negative GeneticPMID:22681890
negative genetic interaction withccq1telomere maintenance protein Ccq1 Negative GeneticPMID:22681890
synthetically rescuescdc6DNA polymerase delta catalytic subunit Cdc6 Synthetic RescuePMID:12589755
positive genetic interaction withcha4transcription factor Cha4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withcho1phosphatidyl-N-dimethylethanolamine N-methyltransferase Positive GeneticPMID:18818364
positive genetic interaction withcho1phosphatidyl-N-dimethylethanolamine N-methyltransferase Positive GeneticPMID:22681890
positive genetic interaction withcho2phosphatidylethanolamine N-methyltransferase Cho2 Positive GeneticPMID:22681890
negative genetic interaction withcip2RNA-binding protein Cip2 Negative GeneticPMID:22681890
positive genetic interaction withcit1citrate synthase Cit1 Positive GeneticPMID:22681890
negative genetic interaction withclr3histone deacetylase (class II) Clr3 Negative GeneticPMID:18818364
negative genetic interaction withclr3histone deacetylase (class II) Clr3 Negative GeneticPMID:22681890
positive genetic interaction withcoq11ubiquinone biosynthesis protein Coq11 Positive GeneticPMID:22681890
negative genetic interaction withcpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Negative GeneticPMID:18818364
positive genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Positive GeneticPMID:18818364
positive genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Positive GeneticPMID:22681890
positive genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Positive GeneticPMID:22681890
synthetically rescuescrb2DNA repair protein Rad9 homolog Crb2 Synthetic RescuePMID:12589755
negative genetic interaction withcsr102sec14 cytosolic factor family phosphatidylinositol transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcwf15complexed with Cdc5 protein Cwf15 Negative GeneticPMID:22681890
negative genetic interaction withcwf21complexed with Cdc5 protein Cwf21 Negative GeneticPMID:18818364
negative genetic interaction withcwf21complexed with Cdc5 protein Cwf21 Negative GeneticPMID:22681890
negative genetic interaction withcwf5RNA-binding protein Cwf5 Negative GeneticPMID:22681890
negative genetic interaction withcxr1mRNA processing factor Negative GeneticPMID:22681890
negative genetic interaction withcyp7cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp7 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:18818364
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
negative genetic interaction withdam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
negative genetic interaction withdap1cytochrome P450 regulator Dap1 Negative GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:18818364
negative genetic interaction withdin1Dhp1p-interacting protein Din1 Negative GeneticPMID:18818364
negative genetic interaction withdni2tetraspan protein implicated in mating Dni2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:22681890
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:22681890
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
negative genetic interaction withdsc5UBX domain containing protein required for Sre1 cleavage Negative GeneticPMID:22681890
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
negative genetic interaction withebs1EST1 family nonsense-mediated mRNA decay (NMD) pathway protein Ebs1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withebs1EST1 family nonsense-mediated mRNA decay (NMD) pathway protein Ebs1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witheif21translation initiation factor eIF2A (predicted) Negative GeneticPMID:18818364
negative genetic interaction witheif21translation initiation factor eIF2A (predicted) Negative GeneticPMID:22681890
negative genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:18818364
negative genetic interaction witherd1Erd1 homolog (predicted) Negative GeneticPMID:22681890
negative genetic interaction witherg28Erg28 protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction witherp2COPII-coated vesicle component Erp2/3/4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfcf2rRNA processing protein Fcf2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfep1iron-sensing transcription factor Fep1 Negative GeneticPMID:22681890
negative genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:18818364
negative genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:22681890
synthetic growth defect withfin1serine/threonine protein kinase, NIMA related Fin1 Synthetic Growth DefectPMID:18931302
synthetic growth defect withfor3formin For3 Synthetic Growth DefectPMID:18931302
positive genetic interaction withfrp1ferric-chelate reductase Frp1 Positive GeneticPMID:22681890
negative genetic interaction withfta6Mis6-Sim4 complex Fta6 Negative GeneticPMID:22681890
negative genetic interaction withftp105Ubp5 interacting protein Ftp105 Negative GeneticPMID:18818364
negative genetic interaction withgar2nucleolar protein required for rRNA processing Negative GeneticPMID:22681890
negative genetic interaction withgas5cell wall protein Gas5, 1,3-beta-glucanosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:18818364
positive genetic interaction withgep3mitochondrial GTPase related protein Gep3 (prediected) Positive GeneticPMID:22681890
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withgid8GID complex subunit Gid8 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withgim1prefoldin subunit 6, Gim1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withgit3G-protein coupled receptor Git3 Positive GeneticPMID:22681890
positive genetic interaction withgit5heterotrimeric G protein beta subunit Git5 Positive GeneticPMID:22681890
negative genetic interaction withgmh4alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgmh5alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgos1SNARE Gos1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgpd1glycerol-3-phosphate dehydrogenase Gpd1 Negative GeneticPMID:22681890
negative genetic interaction withgrx3monothiol glutaredoxin Grx3 Negative GeneticPMID:22681890
positive genetic interaction withhac12-hydroxyacyl-CoA lyase Hac1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withhhf2histone H4 h4.2 Negative GeneticPMID:22681890
synthetic growth defect withhip1hira protein, histone chaperone Hip1 Synthetic Growth DefectPMID:18931302
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withhob3BAR adaptor protein Hob3 Negative GeneticPMID:22681890
negative genetic interaction withhrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:18818364
negative genetic interaction withhrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:22681890
positive genetic interaction withhst2Sirtuin family histone deacetylase Hst2 Positive GeneticPMID:22681890
synthetically rescueshus1checkpoint clamp complex protein Hus1 Synthetic RescuePMID:12589755
negative genetic interaction withimp1importin alpha Negative GeneticPMID:22681890
negative genetic interaction withint6eIF3e subunit Int6 Negative GeneticPMID:22681890
positive genetic interaction withiqw1WD repeat protein, Iqw1 Positive GeneticPMID:22681890
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:18818364
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:22681890
positive genetic interaction withknd1Cullin-associated NEDD8-dissociated protein Knd1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withlaf1Clr6 L associated factor 1 Laf1 Negative GeneticPMID:18818364
negative genetic interaction withlem2LEM domain protein Heh1/Lem2 Negative GeneticPMID:22681890
synthetically rescueslsd1histone demethylase SWIRM1 Synthetic RescuePMID:17434129
negative genetic interaction withlsg1Lsk1 complex gamma subunit Lsg1 Negative GeneticPMID:22681890
negative genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
positive genetic interaction withlub1WD repeat protein Lub1 Positive GeneticPMID:18818364
positive genetic interaction withlub1WD repeat protein Lub1 Positive GeneticPMID:22681890
negative genetic interaction withmal3EB1 family Mal3 Negative GeneticPMID:18818364
negative genetic interaction withmca1transcription factor, zf-fungal binuclear cluster type Mca1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
negative genetic interaction withmed20mediator complex subunit Med20 Negative GeneticPMID:18818364
negative genetic interaction withmed6mediator complex subunit Med6 Negative GeneticPMID:18818364
positive genetic interaction withmga2IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Positive GeneticPMID:18818364
negative genetic interaction withmgr2TIM23 translocase complex subunit Mgr2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmik1mitotic inhibitor kinase Mik1 Negative GeneticPMID:22681890
negative genetic interaction withmms19Dos2 silencing complex subunit Mms19 Negative GeneticPMID:18818364
negative genetic interaction withmms19Dos2 silencing complex subunit Mms19 Negative GeneticPMID:22681890
negative genetic interaction withmoe1translation initiation factor eIF3d Moe1 Negative GeneticPMID:22681890
positive genetic interaction withmpr1histidine-containing response regulator phosphotransferase Mpr1 Positive GeneticPMID:22681890
negative genetic interaction withmre11Mre11 nuclease Negative GeneticPMID:18818364
negative genetic interaction withmsc1Swr1 complex subunit Chk1 Negative GeneticPMID:18818364
negative genetic interaction withmsc1Swr1 complex subunit Chk1 Negative GeneticPMID:22681890
negative genetic interaction withmsn5karyopherin (predicted) Negative GeneticPMID:18818364
positive genetic interaction withmso1endocytic docking protein Mso1 Positive GeneticPMID:22681890
positive genetic interaction withmss1mitochondrial GTPase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withmst2histone acetyltransferase Mst2 Negative GeneticPMID:18818364
negative genetic interaction withmst2histone acetyltransferase Mst2 Negative GeneticPMID:22681890
negative genetic interaction withmto1MT organizer Mto1 Negative GeneticPMID:22681890
negative genetic interaction withmug147Schizosaccharomyces specific protein Mug147 Negative GeneticPMID:22681890
negative genetic interaction withmug170arrestin family Schizosaccharomyces specific protein Mug170 Negative GeneticPMID:22681890
negative genetic interaction withmug80cyclin Clg1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withnas226S proteasome regulatory particle assembly protein Nas2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withnem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
negative genetic interaction withnht1Ino80 complex HMG box subunit Nht1 Negative GeneticPMID:22681890
positive genetic interaction withnop12RNA-binding protein Nop12 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnrm1MBF complex corepressor Nrm1 Negative GeneticPMID:22681890
negative genetic interaction withnto1histone acetyltransferase complex subunit Nto1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withnto1histone acetyltransferase complex subunit Nto1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnup124nucleoporin Nup124 Negative GeneticPMID:22681890
negative genetic interaction withnup132nucleoporin Nup132 Negative GeneticPMID:22681890
negative genetic interaction withnup60nucleoporin Nup60 Negative GeneticPMID:18818364
negative genetic interaction withnup60nucleoporin Nup60 Negative GeneticPMID:22681890
negative genetic interaction withofd12-oxoglutarate and Fe(II) dioxygenase domain containing protein 1 Negative GeneticPMID:22681890
negative genetic interaction withomh1alpha-1,2-mannosyltransferase Omh1 Negative GeneticPMID:22681890
positive genetic interaction withpab2poly(A) binding protein Pab2 Positive GeneticPMID:22681890
positive genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withpar1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:18818364
negative genetic interaction withpck1protein kinase C (PKC)-like Pck1 Negative GeneticPMID:22681890
positive genetic interaction withpdr1ABC transmembrane transporter Pdr1 Positive GeneticPMID:22681890
negative genetic interaction withpfa3palmitoyltransferase Pfa3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:18818364
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
negative genetic interaction withpit1serine/threonine protein kinase, meiotic Pit1 Negative GeneticPMID:22681890
positive genetic interaction withpmk1MAP kinase Pmk1 Positive GeneticPMID:22681890
negative genetic interaction withpmr1P-type ATPase, calcium transporting Pmr1 Negative GeneticPMID:22681890
negative genetic interaction withpng2ING family homolog Png2 Negative GeneticPMID:18818364
negative genetic interaction withpof10F-box protein Pof10 Negative GeneticPMID:22681890
negative genetic interaction withpof12F-box protein Pof12 Negative GeneticPMID:22681890
negative genetic interaction withpof14F-box protein Pof14 Negative GeneticPMID:22681890
negative genetic interaction withpof2F-box protein Pof2 Negative GeneticPMID:22681890
synthetic growth defect withpof3F-box protein Pof3 Synthetic Growth DefectPMID:18931302
negative genetic interaction withpof8F-box protein Pof8 Negative GeneticPMID:22681890
negative genetic interaction withpom1DYRK family protein kinase Pom1 Negative GeneticPMID:18818364
negative genetic interaction withpom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
negative genetic interaction withpom152nucleoporin Pom152 Negative GeneticPMID:22681890
negative genetic interaction withppa2serine/threonine protein phosphatase Ppa2 Negative GeneticPMID:22681890
negative genetic interaction withppk31serine/threonine protein kinase Ppk31 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withppk38Ark1/Prk1 family protein kinase Ppk38 Positive GeneticPMID:22681890
positive genetic interaction withppk6serine/threonine protein kinase Ppk6 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withprp4serine/threonine protein kinase Prp4 Negative GeneticPMID:22681890
negative genetic interaction withprp43ATP-dependent RNA helicase Prp43 Negative GeneticPMID:22681890
positive genetic interaction withprz1calcineurin responsive transcription factor Prz1 Positive GeneticPMID:22681890
positive genetic interaction withpst2Clr6 histone deacetylase complex subunit Pst2 Positive GeneticPMID:22681890
negative genetic interaction withptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
negative genetic interaction withptc3protein phosphatase 2c homolog 3 Negative GeneticPMID:22681890
negative genetic interaction withptf2Mst2 histone acetytransferase acytyltransferase complex subunit Negative GeneticPMID:22681890
positive genetic interaction withptr2PTR family peptide transmembrane transporter Ptr2 Positive GeneticPMID:22681890
negative genetic interaction withpuf3RNA-binding protein Puf3 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withpyp1tyrosine phosphatase Pyp1 Positive GeneticPMID:22681890
synthetically rescuesrad1checkpoint clamp complex protein Rad1 Synthetic RescuePMID:12589755
synthetically rescuesrad17RFC related checkpoint protein Rad17 Synthetic RescuePMID:12589755
positive genetic interaction withrad2514-3-3 protein Rad25 Positive GeneticPMID:18818364
rescued byrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Phenotypic SuppressionPMID:12589755
rescued byrad3ATR checkpoint kinase Rad3 Phenotypic SuppressionPMID:12589755
negative genetic interaction withrad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:18818364
negative genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:18818364
synthetically rescuesrad9checkpoint clamp complex protein Rad9 Synthetic RescuePMID:12589755
negative genetic interaction withrap1telomere binding protein Rap1 Negative GeneticPMID:18818364
negative genetic interaction withrav2RAVE complex subunit Rav2 Negative GeneticPMID:22681890
negative genetic interaction withrdp1RNA-directed RNA polymerase Rdp1 Negative GeneticPMID:18818364
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:18818364
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:22681890
negative genetic interaction withrem1meiosis-specific cyclin Rem1 Negative GeneticPMID:22681890
negative genetic interaction withres2MBF transcription factor complex subunit Res2 Negative GeneticPMID:18818364
positive genetic interaction withrfp2SUMO-targeted ubiquitin-protein ligase subunit Rfp2 Positive GeneticPMID:22681890
negative genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:18818364
negative genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:22681890
negative genetic interaction withrik1silencing protein Rik1 Negative GeneticPMID:18818364
positive genetic interaction withrnh201ribonuclease H2 complex subunit Rnh201 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrod1arrestin/PY protein involved in ubiquitin-mediated endocytosis Rod1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrog1acylglycerol lipase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
positive genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl210260S ribosomal protein L21 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl70260S ribosomal protein L7 Positive GeneticPMID:22681890
positive genetic interaction withrpn130219S proteasome regulatory subunit Rpn13b Positive GeneticPMID:22681890
positive genetic interaction withrps10140S ribosomal protein S3a Positive GeneticPMID:22681890
positive genetic interaction withrps240140S ribosomal protein S24 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrps340S ribosomal protein S3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrsc1RSC complex subunit Rsc1 Negative GeneticPMID:18818364
negative genetic interaction withrsc4RSC complex subunit Rsc4 Negative GeneticPMID:18818364
negative genetic interaction withrsc4RSC complex subunit Rsc4 Negative GeneticPMID:22681890
negative genetic interaction withrsv2transcription factor Rsv2 Negative GeneticPMID:18818364
negative genetic interaction withrtf2replication termination factor Rtf2 Negative GeneticPMID:22681890
negative genetic interaction withrud3Golgi matrix protein Rud3 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withryh1GTPase Ryh1 Positive GeneticPMID:18818364
positive genetic interaction withsaf4splicing associated factor Saf4 Positive GeneticPMID:22681890
negative genetic interaction withsaf5splicing factor Saf5 Negative GeneticPMID:22681890
negative genetic interaction withsap114U2 snRNP subunit Sap114 Negative GeneticPMID:22681890
negative genetic interaction withsap14U2 snRNP-associated protein SF3B14 Sap14 Negative GeneticPMID:22681890
negative genetic interaction withsap145U2 snRNP-associated protein Sap145 Negative GeneticPMID:22681890
negative genetic interaction withsat1Golgi membrane exchange factor subunit Sat1 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withsck2serine/threonine protein kinase Sck2 Positive GeneticPMID:24463365
positive genetic interaction withsck2serine/threonine protein kinase Sck2 Positive GeneticPMID:22681890
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:18818364
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
positive genetic interaction withsdc1Dpy-30 domain protein Sdc1 Positive GeneticPMID:18818364
positive genetic interaction withsdc1Dpy-30 domain protein Sdc1 Positive GeneticPMID:22681890
positive genetic interaction withsdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:18818364
negative genetic interaction withsec28coatomer epsilon subunit (predicted) Negative GeneticPMID:18818364
positive genetic interaction withsec72Sec7 domain protein, ARF GEF Sec72 Positive GeneticPMID:22681890
negative genetic interaction withset3histone lysine methyltransferase Set3 Negative GeneticPMID:18818364
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
positive genetic interaction withshk2PAK-related kinase Shk2 Positive GeneticPMID:18818364
negative genetic interaction withski2Ski complex RNA helicase Ski2 (predicted) Negative GeneticPMID:18818364
synthetic growth defect withslm9hira protein Slm9 Synthetic Growth DefectPMID:18931302
negative genetic interaction withslx9ribosome biogenesis protein Slx9 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withsnf30SWI/SNF complex subunit Snf30 Positive GeneticPMID:18818364
positive genetic interaction withsnf5SWI/SNF complex subunit Snf5 Positive GeneticPMID:22681890
positive genetic interaction withsno1glutamine aminotransferase subunit Sno1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withsnt2Lid2 complex subunit Snt2 Negative GeneticPMID:18818364
negative genetic interaction withsnt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
negative genetic interaction withSPAC1296.01cphosphoacetylglucosamine mutase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC12B10.01cHECT-type ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1399.04curacil phosphoribosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC13G6.09SSU-rRNA maturation protein Tsr4 homolog 2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC13G6.15ccalcipressin (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC144.05ATP-dependent DNA helicase/ ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1486.03cRNA-binding splicing factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC14C4.01cDUF1770 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC15A10.06CPA1 sodium ion/proton antiporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC15A10.07Schizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC17H9.08mitochondrial coenzyme A transmembrane transporter (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1952.06cspliceosomal complex subunit (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPAC1952.06cspliceosomal complex subunit (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC1B3.08COP9 signalosome complex subunit 12 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC227.17cconserved protein Positive GeneticPMID:22681890
negative genetic interaction withSPAC22H10.02conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC23C4.09cDNA-binding TFAR19-related protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC2C4.06ctRNA (cytosine-5-)-methyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC30C2.07Schizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPAC3H1.08cmitochondrial calcium uniporter regulator (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC4A8.06cesterase/lipase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC4G8.03cRNA-binding protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC56E4.07N-acetyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC694.02DEAD/DEAH box helicase Negative GeneticPMID:22681890
negative genetic interaction withSPAC6G9.15cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC922.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC977.13cPositive GeneticPMID:22681890
negative genetic interaction withSPAC9G1.07Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC9G1.10cinositol polyphosphate phosphatase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPAP27G11.11cdubious Negative GeneticPMID:22681890
positive genetic interaction withSPAPB2B4.04cvacuolar calcium transporting P-type ATPase P2 type, Pmc1 Positive GeneticPMID:22681890
negative genetic interaction withSPBC106.12cTHO complex subunit (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC1347.09hexaprenyldihydroxybenzoate methyltransferase, Coq3 variant (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC15C4.04camino acid transmembrane transporter (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC1683.04glycosyl hydrolase family 3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC1685.04Schizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:18818364
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
positive genetic interaction withSPBC1773.16ctranscription factor, zf-fungal binuclear cluster type(predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPBC17D11.08WD repeat protein, DDB1 and CUL4-associated factor 7 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC1861.07elongin C (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC1861.07elongin C (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC18H10.05WD repeat protein, human WDR44 family Negative GeneticPMID:18818364
positive genetic interaction withSPBC20F10.07GRAM domain protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC25B2.08Schizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC29A10.16ccytochrome b5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC2F12.05csterol binding ankyrin repeat protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC30D10.03cIMP 5'-nucleotidase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
negative genetic interaction withSPBC336.13cmitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC365.16conserved protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC577.11DUF3074 family protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC651.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC713.03mitochondrial D-lactate dehydrogenase, cytochrome (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBCPT2R1.01cS. pombe specific DUF999 protein family 9 Negative GeneticPMID:22681890
positive genetic interaction withSPBP4H10.14cSchizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withspc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:18818364
positive genetic interaction withSPCC1259.08conserved fungal protein, DUF2457 family Positive GeneticPMID:22681890
negative genetic interaction withSPCC126.08clectin family glycoprotein receptor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC1795.10cSed5 Vesicle Protein Svp26 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC18.17cproteasome assembly chaperone (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC1827.03cacetyl-CoA ligase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC188.10cPositive GeneticPMID:22681890
negative genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC417.11cglutamate-1-semialdehyde 2,1-aminomutase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC4B3.03cmitochondrial morphology protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC584.11cSvf1 family protein Svf1 Positive GeneticPMID:22681890
negative genetic interaction withSPCC645.12cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withspn1mitotic septin Spn1 Negative GeneticPMID:18818364
enhances phenotype ofspt5DSIF transcription elongation factor complex subunit Spt5 Phenotypic EnhancementPMID:22876190
positive genetic interaction withsrb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
negative genetic interaction withssb3DNA replication factor A subunit Ssb3 Negative GeneticPMID:22681890
positive genetic interaction withstt41-phosphatidylinositol 4-kinase Stt4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsum1translation initiation factor eIF3i Positive GeneticPMID:22681890
negative genetic interaction withswc2Swr1 complex complex subunit Swc2 Negative GeneticPMID:22681890
positive genetic interaction withswd1Set1C complex subunit Swd1 Positive GeneticPMID:18818364
positive genetic interaction withswd1Set1C complex subunit Swd1 Positive GeneticPMID:22681890
positive genetic interaction withswd2Set1C complex subunit Swd2.1 Positive GeneticPMID:18818364
positive genetic interaction withswd2Set1C complex subunit Swd2.1 Positive GeneticPMID:22681890
negative genetic interaction withswd22mRNA cleavage and polyadenylation specificity factor complex subunit, WD repeat protein Swd22 Negative GeneticPMID:18818364
negative genetic interaction withswd22mRNA cleavage and polyadenylation specificity factor complex subunit, WD repeat protein Swd22 Negative GeneticPMID:22681890
positive genetic interaction withswd3WD repeat protein Swd3 Positive GeneticPMID:18818364
positive genetic interaction withswd3WD repeat protein Swd3 Positive GeneticPMID:22681890
negative genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:18818364
negative genetic interaction withtcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:22681890
negative genetic interaction withtea2kinesin-like protein Tea2 Negative GeneticPMID:18818364
negative genetic interaction withtea2kinesin-like protein Tea2 Negative GeneticPMID:22681890
rescued bytel1ATM checkpoint kinase Phenotypic SuppressionPMID:12589755
negative genetic interaction withtif38translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
negative genetic interaction withtip1CLIP170 family protein Tip1 Negative GeneticPMID:18818364
negative genetic interaction withtip1CLIP170 family protein Tip1 Negative GeneticPMID:22681890
negative genetic interaction withtma20RNA-binding protein Tma20 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withtma20RNA-binding protein Tma20 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtol13'(2'),5'-bisphosphate nucleotidase/inositol-1,4- bisphosphate 1-phosphatase Negative GeneticPMID:22681890
positive genetic interaction withtrm112protein and tRNA methyltransferase regulatory subunit Trm112 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtrm12tRNA methyltransferase Trm12 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtrs130TRAPP complex subunit Trs130 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withtrx2mitochondrial thioredoxin Trx2 Positive GeneticPMID:22681890
positive genetic interaction withtsc2tuberin Positive GeneticPMID:22681890
negative genetic interaction withubp3ubiquitin C-terminal hydrolase Ubp3 Negative GeneticPMID:18818364
negative genetic interaction withubp4ubiquitin C-terminal hydrolase Ubp4 Negative GeneticPMID:18818364
positive genetic interaction withuch1ubiquitin C-terminal hydrolase Uch1 Positive GeneticPMID:22681890
positive genetic interaction withuds1septation protein Uds1 Positive GeneticPMID:22681890
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withura5orotate phosphoribosyltransferase Ura5 Positive GeneticPMID:18818364
positive genetic interaction withura5orotate phosphoribosyltransferase Ura5 Positive GeneticPMID:22681890
positive genetic interaction withvht1vitamin H transmembrane transporter Vht1 Positive GeneticPMID:22681890
positive genetic interaction withvms1Cdc48p-Npl4p-Vms1p AAA ATPase complex subunit involved in ER associated ubiquitin-dependent protein catabolic process Vms1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withvps1301chorein homolog Vps13a (predicted) Negative GeneticPMID:22681890
positive genetic interaction withvps35retromer complex subunit Vps35 Positive GeneticPMID:22681890
negative genetic interaction withvps901guanyl-nucleotide exchange factor Vps901 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withvrp1verprolin Positive GeneticPMID:18818364
negative genetic interaction withwbp4WW domain-binding protein Wbp4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withwhi2phosphatase activator Whi2 Negative GeneticPMID:18818364
negative genetic interaction withwis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Negative GeneticPMID:18818364
negative genetic interaction withwtf16wtf element Wtf16 Negative GeneticPMID:22681890
synthetically rescuesxap5xap-5-like protein Synthetic RescuePMID:24957674
negative genetic interaction withyaf9YEATS family histone acetyltransferase subunit Yaf9 Negative GeneticPMID:18818364
positive genetic interaction withyip5Rab GTPase binding Yip5 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:18818364
negative genetic interaction withypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Negative GeneticPMID:18818364
negative genetic interaction withzds1zds family protein phosphatase type A regulator Zds1 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withzfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Positive GeneticPMID:22681890
positive genetic interaction withzrt2ZIP zinc transmembrane transporter Zrt2 (predicted) Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC306.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC306.04c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC306.04c BioGRID Interaction Datasets
Expression Viewer SPCC306.04c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC306.04c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC306.04c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC306.04c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC306.04c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC306.04c Transcriptome Viewer (Bähler Lab)
GEO SPCC306.04c GEO profiles
PInt SPCC306.04c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC306.04c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC306.04c Fission yeast phenotypic data & analysis
Cyclebase SPCC306.04c.1 Cell Cycle Data
SPD / RIKEN39/39B01Orfeome Localization Data
UniProtKB/SwissProtQ9Y7R4Histone-lysine N-methyltransferase, H3 lysine-4 specific
ModBaseQ9Y7R4Database of comparative protein structure models
STRINGQ9Y7R4Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587812histone lysine methyltransferase Set1
RefSeq mRNANM_001022805972h- histone lysine methyltransferase Set1 (set1), mRNA
European Nucleotide ArchiveCAB41652.1ENA Protein Mapping
MetaCycPWY-642426,27-dehydrozymosterol metabolism
KEGG_Enzyme00310+2.1.1.43Lysine degradation
UniParcUPI000006BCFAUniProt Archive

Literature for set1

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Release Version: PomBase:26_52 - 11 May 2015