SPCC306.06c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPCC306.06c Feature Typeprotein coding
Synonyms Name Description
ProductER membrane protein, BIG1 family (predicted) Product Size311aa, 34.64 kDa
Genomic Location Chromosome III, 419553-418005 (1549nt); CDS:419473-418476 (998nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006078(1->6)-beta-D-glucan biosynthetic processISSUniProtKB:Q875I7GO_REF:00000016
GO:0009272fungal-type cell wall biogenesisISOSGD:S000001143GO_REF:000002465
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0000329fungal-type vacuole membraneIDAPMID:1682337291
GO:0030176integral component of endoplasmic reticulum membraneISOSGD:S000001143GO_REF:000002467
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopySPCC306.06cΔNullPMID:204732891309
MicroscopySPCC306.06cΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0001098sensitive to 4-nitroquinoline N-oxideCell growth assaySPCC306.06cΔNullPECO:0000137, PECO:0000005PMID:19264558159
expressivity FYPO_EXT:0000002
FYPO:0000097sensitive to caffeineCell growth assaySPCC306.06cΔNullPECO:0000137PMID:1967230695
expressivity FYPO_EXT:0000001
FYPO:0000085sensitive to camptothecinCell growth assaySPCC306.06cΔNullPECO:0000137, PECO:0000005PMID:19264558200
expressivity FYPO_EXT:0000002
FYPO:0000087sensitive to hydrogen peroxideCell growth assaySPCC306.06cΔNullPECO:0000137PMID:19672306112
expressivity FYPO_EXT:0000001
FYPO:0000088sensitive to hydroxyureaCell growth assaySPCC306.06cΔNullPECO:0000137, PECO:0000005PMID:19264558233
expressivity FYPO_EXT:0000003

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000054abnormal microtubule cytoskeleton organizationnot recorded (overexpression)PMID:1579792544
FYPO:0002151inviable sporeMicroscopySPCC306.06cΔNullPECO:0000005, PECO:0000137PMID:23697806447
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1419553419382
2419319418005

UTRs

Region Start End Reference
five_prime_UTR419553419474PMID:21511999
three_prime_UTR418475418005PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05827 Pfam IPR024722 ATPase, V1 complex, subunit S1 21 295 1
TMhelix TMHMM 271 293 959
Low complexity (SEG) seg 89 105
SignalP-noTM signalp 1 17 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide278
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 111.37 Da
Charge -10.00
Isoelectric point 4.65
Molecular weight 34.64 kDa
Number of residues 311
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
5109.15during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.7during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
6.1during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi only603
conserved in fungi4564
conserved in eukaryotes4482
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPCC306.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC306.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC306.06c BioGRID Interaction Datasets
Expression Viewer SPCC306.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC306.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC306.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC306.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC306.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC306.06c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC306.06c Cell Cycle Data
GEO SPCC306.06c GEO profiles
PInt SPCC306.06c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2539326ER membrane protein, BIG1 family (predicted)
EntrezGene2539326ER membrane protein, BIG1 family (predicted)
SPD / RIKEN14/14F02Orfeome Localization Data
UniProtKB/SwissProtQ9Y7R6Protein big1
ModBaseQ9Y7R6Database of comparative protein structure models
StringQ9Y7R6Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587814ER membrane protein, BIG1 family (predicted)
RefSeq mRNANM_001022807972h- ER membrane protein, BIG1 family (predicted) (SPCC306.06c), mRNA
European Nucleotide ArchiveCAB41654ENA Protein Mapping
UniParcUPI0000069B7FUniProt Archive

Literature for SPCC306.06c

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014