SPCC306.07c


Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPCC306.07c Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Cic1/Utp30 family (predicted) Product Size284aa, 32.40 kDa
Genomic Location Chromosome III, 421247-419629 (1619nt); CDS:421135-420000 (1136nt)

Ensembl Gene Location
  1. set1
  2. ins1
  3. big1
  4. SPCC306.07c
  5. mdh1
  6. cap1
  7. wtf8
GO Biological Process

GO Slim Terms

ribosome biogenesis


Term NameCount
ribosomal large subunit biogenesis46
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nucleolus366
Annotation ExtensionEvidenceWith/FromReference
nucleus2692
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationSPCC306.07cΔ3837

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPCC306.07cΔ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons421247..421073, 421012..420879, 420657..419629
Intron421072..421013, 420878..420658
5' UTR421247..421136PMID:21511999
3' UTR419999..419629PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 26 238 5
PTHR23105 HMMPANTHER 61 262 8
PTHR23105:SF31 HMMPANTHER 61 262 2
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 177 244 5
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 24 242 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.10 Da
Charge 24.50
Codon Adaptation Index 0.37
Isoelectric point 10.43
Molecular weight 32.40 kDa
Number of residues 284
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPCC306.07c

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3642during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3936during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
4092during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
4360during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
1056.49during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
3963during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
1958.54during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.3during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.41during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4605
conserved in eukaryotes4515
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2505
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPCC306.07c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bymlo3RNA binding protein Mlo3 Affinity Capture-MSPMID:21436456
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPCC306.07c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withmug51variant protein kinase 19 family protein Negative GeneticPMID:22681890
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC584.03cRan GTP-binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsgf73SAGA complex subunit Sgf73 Negative GeneticPMID:25076038
negative genetic interaction withski2Ski complex RNA helicase Ski2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgpd1glycerol-3-phosphate dehydrogenase Gpd1 Negative GeneticPMID:22681890
negative genetic interaction withrrp2ATP-dependent DNA helicase, ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withutp16U3 snoRNP-associated protein Utp16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
negative genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcsr102sec14 cytosolic factor family, glycerophospholipid-transfer protein Crs102 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgcd10tRNA (m1A) methyltransferase Gcd10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:18818364
positive genetic interaction withvps71Swr1 complex subunit Vps71 Positive GeneticPMID:18818364
positive genetic interaction withSPCC126.13chistone deacetylase complex subunit, SAP128 family (predicted) Positive GeneticPMID:18818364
positive genetic interaction withswd1Set1C complex subunit Swd1 Positive GeneticPMID:22681890
positive genetic interaction withrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Positive GeneticPMID:18818364
positive genetic interaction withsrs2ATP-dependent DNA helicase, UvrD subfamily Positive GeneticPMID:18818364
positive genetic interaction withfml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Positive GeneticPMID:18818364
positive genetic interaction withspn1mitotic septin Spn1 Positive GeneticPMID:18818364
positive genetic interaction withrbd4rhomboid family protease associated with COP1 coated vesicle (predicted) Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC306.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC306.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC306.07c BioGRID Interaction Datasets
Expression Viewer SPCC306.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC306.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC306.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC306.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC306.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC306.07c Transcriptome Viewer (Bähler Lab)
GEO SPCC306.07c GEO profiles
PInt SPCC306.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC306.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC306.07c Fission yeast phenotypic data & analysis
Cyclebase SPCC306.07c.1 Cell Cycle Data
SPD / RIKEN17/17H06Orfeome Localization Data
UniProtKB/SwissProtQ9Y7R7Putative ribosome biogenesis protein C306.07c
ModBaseQ9Y7R7Database of comparative protein structure models
STRINGQ9Y7R7Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587815U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
RefSeq mRNANM_001022808972h- U3 snoRNP-associated protein Cic1/Utp30 family (predicted) (SPCC306.07c), mRNA

Literature for SPCC306.07c

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016