SPCC306.07c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPCC306.07c Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Cic1/Utp30 family (predicted) Product Size284aa, 32.40 kDa
Genomic Location Chromosome III, 421247-419629 (1619nt); CDS:421135-420000 (1136nt)

Ensembl Gene Location
  1. set1
  2. ins1
  3. big1
  4. SPCC306.07c
  5. mdh1
  6. cap1
  7. wtf8
GO Biological Process

GO Slim Terms

ribosome biogenesis


Term NameCount
ribosomal large subunit biogenesis41
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nucleolus360
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationSPCC306.07cΔNull3792

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologySPCC306.07cΔNull3092
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons421247..421073, 421012..420879, 420657..419629
mRNA421247..419629
5' UTR421247..421136PMID:21511999
CDS421135..421073, 421012..420879, 420657..420000
3' UTR419999..419629PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 26 238 5
PTHR23105 HMMPANTHER 65 282 8
PTHR23105:SF5 HMMPANTHER 65 282 2
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 177 244 5
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 24 242 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.10 Da
Charge 24.50
Isoelectric point 10.43
Molecular weight 32.40 kDa
Number of residues 284
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3642during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
3936during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
4092during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
4360during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
1056.49during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
3963during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
1958.54during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.3during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.41during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bymlo3RNA binding protein Mlo3 Affinity Capture-MSPMID:21436456
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withcsr102sec14 cytosolic factor family phosphatidylinositol transmembrane transporter (predicted) Negative GeneticPMID:22681890
positive genetic interaction withfml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Positive GeneticPMID:18818364
negative genetic interaction withgcd10tRNA (m1A) methyltransferase Gcd10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgpd1glycerol-3-phosphate dehydrogenase Gpd1 Negative GeneticPMID:22681890
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
negative genetic interaction withmug51variant protein kinase 19 family protein Negative GeneticPMID:22681890
negative genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:18818364
positive genetic interaction withrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Positive GeneticPMID:18818364
negative genetic interaction withrrp2ATP-dependent DNA helicase, ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsgf73SAGA complex subunit Sgf73 Negative GeneticPMID:25076038
positive genetic interaction withSPAC19B12.06crhomboid family protease (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC126.13chistone deacetylase complex subunit, SAP128 family (predicted) Positive GeneticPMID:18818364
negative genetic interaction withSPCC550.03cSki complex RNA helicase Ski2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC584.03cRan GTP-binding protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withspn1mitotic septin Spn1 Positive GeneticPMID:18818364
positive genetic interaction withsrs2ATP-dependent DNA helicase, UvrD subfamily Positive GeneticPMID:18818364
positive genetic interaction withswd1Set1C complex subunit Swd1 Positive GeneticPMID:22681890
negative genetic interaction withutp16U3 snoRNP-associated protein Utp16 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withvps71Swr1 complex subunit Vps71 Positive GeneticPMID:18818364
External References
Database Identifier Description
NBRP SPCC306.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC306.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC306.07c BioGRID Interaction Datasets
Expression Viewer SPCC306.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC306.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC306.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC306.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC306.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC306.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC306.07c Cell Cycle Data
GEO SPCC306.07c GEO profiles
PInt SPCC306.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC306.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC306.07c Fission yeast phenotypic data & analysis
SPD / RIKEN17/17H06Orfeome Localization Data
UniProtKB/SwissProtQ9Y7R7Putative ribosome biogenesis protein C306.07c
ModBaseQ9Y7R7Database of comparative protein structure models
STRINGQ9Y7R7Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587815U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
RefSeq mRNANM_001022808972h- U3 snoRNP-associated protein Cic1/Utp30 family (predicted) (SPCC306.07c), mRNA
European Nucleotide ArchiveCAB41655.1ENA Protein Mapping
UniParcUPI0000069F7DUniProt Archive

Literature for SPCC306.07c

Search: Europe PMC or PubMed

Release Version: PomBase:25_50 - 10 Mar 2015