mug73 (SPCC31H12.02c)

Gene Standard Namemug73 Characterisation Statusbiological_role_inferred
Systematic IDSPCC31H12.02c Feature Typeprotein coding
Synonyms Name DescriptionMeiotically Upregulated Gene
Productplasma membrane transmembrane transport regulator (predicted) Product Size306aa, 34.66 kDa
Genomic Location Chromosome III, 624527-623516 (1012nt); CDS:624527-623607 (921nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
meiotic cell cycle441
Annotation ExtensionEvidenceWith/FromReference
regulation of ion transmembrane transport11
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
integral component of membrane1018
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationmug73ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphology3092
penetrance FYPO_EXT:0000001mug73ΔNull
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01036 Pfam IPR029730 Archaeal/bacterial/fungal rhodopsin-like 29 247 1
SM01021 SMART IPR029730 Archaeal/bacterial/fungal rhodopsin-like 24 256 1
TMhelix TMHMM 188 210 959
TMhelix TMHMM 125 147 959
TMhelix TMHMM 99 121 959
TMhelix TMHMM 223 245 959
TMhelix TMHMM 154 173 959
TMhelix TMHMM 60 79 959
TMhelix TMHMM 28 50 959
1.20.1070.10 Gene3D 22 254 1
SSF81321 SuperFamily 21 253 1
PR00251 PRINTS IPR001425 Archaeal/bacterial/fungal rhodopsin 100 121 1
PR00251 PRINTS IPR001425 Archaeal/bacterial/fungal rhodopsin 193 211 1
PR00251 PRINTS IPR001425 Archaeal/bacterial/fungal rhodopsin 56 76 1
PR00251 PRINTS IPR001425 Archaeal/bacterial/fungal rhodopsin 152 173 1

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 113.28 Da
Charge 2.50
Isoelectric point 7.33
Molecular weight 34.66 kDa
Number of residues 306
Gene Expression

Qualitative Gene Expression

RNA levelincreased during GO:0051321experimental evidencePMID:16303567

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.47during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
0.27during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi only619
conserved in fungi4604
conserved in eukaryotes4516

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
SPBC1271.03cNLI interacting factor family phosphatase (predicted) Positive GeneticPMID:22681890
shk2PAK-related kinase Shk2 Positive GeneticPMID:22681890
ppk9serine/threonine protein kinase Ppk9 (predicted) Positive GeneticPMID:22681890
ace2transcription factor Ace2 Positive GeneticPMID:22681890
rnh201ribonuclease H2 complex subunit Rnh201 (predicted) Positive GeneticPMID:22681890
SPAC27F1.06cFKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Positive GeneticPMID:22681890
pho1acid phosphatase Pho1 Positive GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Positive GeneticPMID:22681890
nup132nucleoporin Nup132 Negative GeneticPMID:22681890
SPAC732.02cfructose-2,6-bisphosphate 2-phosphatase activity (predicted) Positive GeneticPMID:22681890
hht2histone H3 h3.2 Positive GeneticPMID:22681890
SPBC1348.10cphospholipase (predicted) Positive GeneticPMID:22681890
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:22681890
rik1silencing protein Rik1 Negative GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:22681890
pap1transcription factor Pap1/Caf3 Positive GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Positive GeneticPMID:22681890
SPBC725.05cnucleotide pyrophosphatase (predicted) Positive GeneticPMID:22681890
SPBC17A3.06phosphoprotein phosphatase (predicted) Positive GeneticPMID:22681890
gmh2alpha-1,2-galactosyltransferase Gmh2 (predicted) Positive GeneticPMID:22681890
SPAC1952.10cconserved fungal protein Positive GeneticPMID:22681890
SPBC1778.03cNADH pyrophosphatase (predicted) Positive GeneticPMID:22681890
pub3HECT-type ubiquitin-protein ligase E3 Pub3 (predicted) Positive GeneticPMID:22681890
hip4histone promoter control protein Hip4 Positive GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
rpb7DNA-directed RNA polymerase complex II subunit Rpb7 Negative GeneticPMID:22681890
SPAC6F6.11cpyridoxine-pyridoxal-pyridoxamine kinase (predicted) Positive GeneticPMID:22681890
sfp1transcription factor Sfp1 (predicted) Positive GeneticPMID:22681890
amk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:22681890
mak3histidine kinase Mak3 Positive GeneticPMID:22681890
swd3WD repeat protein Swd3 Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
tps1alpha,alpha-trehalose-phosphate synthase Positive GeneticPMID:22681890
mkh1MEK kinase (MEKK) Mkh1 Positive GeneticPMID:22681890
lsb5cortical component Lsb5 (predicted) Positive GeneticPMID:22681890
tea4tip elongation aberrant protein Tea4 Positive GeneticPMID:22681890
SPAC4C5.01haloacid dehalogenase-like hydrolase Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC31H12.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC31H12.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC31H12.02c BioGRID Interaction Datasets
Expression Viewer SPCC31H12.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC31H12.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC31H12.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC31H12.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC31H12.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC31H12.02c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC31H12.02c Cell Cycle Data
GEO SPCC31H12.02c GEO profiles
PInt SPCC31H12.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC31H12.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC31H12.02c Fission yeast phenotypic data & analysis
SPD / RIKEN12/12H01Orfeome Localization Data
UniProtKB/SwissProtO74870Meiotically up-regulated gene 73 protein
ModBaseO74870Database of comparative protein structure models
STRINGO74870Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587895membrane transporter (predicted)
RefSeq mRNANM_001022887972h- membrane transporter (predicted) (mug73), mRNA
European Nucleotide ArchiveCAA21219.1ENA Protein Mapping
UniParcUPI00000695BBUniProt Archive

Literature for mug73

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015