hem12 (SPCC4B3.05c)

Synonyms ChromosomeIII
Producturoporphyrinogen decarboxylase Hem12 (predicted) Gene Start1166304
Feature Typeprotein coding Gene End1168277
Name Description CDS Start1166571
Characterisation Statusbiological_role_inferred CDS End1167837

Ensembl Gene Location
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
111663041166558
211665711166604
311666621166696
411667431166767
511668151167323
611673731168277

Protein Feature Information

Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF01208 Pfam Uroporphyrinogen decarboxylase (URO-D) 1 352 438.5 1
51726 Superfamily 1 355 381 2
PS00906 scanprosite Uroporphyrinogen decarboxylase (URO-D) 19 28 1
PS00907 scanprosite Uroporphyrinogen decarboxylase (URO-D) 141 157 1
TIGR01464 Tigrfam Uroporphyrinogen decarboxylase HemE 5 351 651.3 1

Protein Properties

Ave. residue weight 113.00 Da
Charge 3.00
Isoelectric point 7.49
Molecular weight 40.11 kDa
Number of residues 355
Sequence

Fission Yeast Phenotype

Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

Biological Process
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0006783heme biosynthetic processISS SGD:S000002454GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006783

Cellular Component
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0005634nucleusISS SGD:S000002454GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
IDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference
GO:0005737cytoplasmISS SGD:S000002454GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005737
GO:0005829cytosolIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005829

Molecular Function
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0004853uroporphyrinogen decarboxylase activityISS SGD:S000002454GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0004853
IEAGO_REF:0000002
IEAGO_REF:0000003

Disease Association

DescriptionSourceAll Genes
porphyriaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000225

Species Distribution

DescriptionSourceAll Genes
conserved in BacteriaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000086
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
predominantly uniformly single copy (one to one)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000104
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Manually Curated Orthologs

SpeciesGeneDescription


External References

Database Identifier Description
NBRP SPCC4B3.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC4B3.05c Retrieval of eukaryotic orthologs
BioGrid SPCC4B3.05c BioGRID Interaction Datasets
Bähler Lab SPCC4B3.05c Cell Cycle Expression Profile
Bähler Lab SPCC4B3.05c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC4B3.05c Pheromone response/mating expression profiles
Bähler Lab SPCC4B3.05c Environmental stress expression profiles
Bähler Lab SPCC4B3.05c Bähler Lab Transcriptome Viewer
Cyclebase SPCC4B3.05c Cell Cycle Data
Entrez Gene SPCC4B3.05c Link to Entrez Gene
SPD / RIKEN44/44B02Orfeome Localization Data
UniProtKB/SwissProtQ9USJ5Uroporphyrinogen decarboxylase
ArrayExpressQ9USJ5Link to ArrayExpress
RefSeq PeptideNP_588085uroporphyrinogen decarboxylase Hem12 (predicted)
RefSeq mRNANM_001023077972h- uroporphyrinogen decarboxylase Hem12 (predicted) (hem12), mRNA
European Nucleotide ArchiveCU329672ENA EMBL mapping
European Nucleotide ArchiveCAB60679ENA Protein Mapping
UniParcUPI0000D99366UniProt Archive

Literature for hem12

Search: UK PMC or PubMed