mdj1 (SPCC4G3.14)

Gene Standard Namemdj1 ChromosomeIII
Systematic IDSPCC4G3.14 Gene Start445260
Synonyms Gene End442924
Productmitochondrial DNAJ domain protein Mdj1 (predicted) Gene Length2337
Feature Typeprotein coding CDS Start444756
Name Description CDS End443170
Characterisation Statusbiological_role_inferred CDS Length1587

Ensembl Gene Location
  1. SPNCRNA.1138
  2. rix1
  3. SPCC4G3.17
  4. SPCC4G3.16
  5. not2
  6. mdj1
  7. SPCC4G3.13c
  8. SPCC4G3.12c
  9. mug154
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000091sensitive to thiabendazolecompetitive growth assay evidencemdj1delta (deletion)deletionPMID:20537132
FYPO:0000269sensitive to microtubule depolymerizing drugscompetitive growth assay evidencemdj1delta (deletion)deletionPMID:20537132
FYPO:0002061inviable vegetative cell populationMicroscopymdj1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005524ATP bindingIEAIPR012724GO_REF:0000002
GO:0030544Hsp70 protein bindingISMPFAM:PF00226GO_REF:0000001
GO:0046872metal ion bindingIEAUniProtKB:KW-0479GO_REF:0000037
GO:0051082unfolded protein bindingISOSGD:S000001878GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000002mitochondrial genome maintenanceISOSGD:S000001878GO_REF:0000024
GO:0034605cellular response to heatISOSGD:S000001878GO_REF:0000024
GO:0042026protein refoldingISOSGD:S000001878GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005739mitochondrionIDAPMID:16823372
GO:0005743mitochondrial inner membraneISOSGD:S000001878GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1445260442924

References

Region Start End Reference
five_prime_UTR445260444757PMID:21511999
three_prime_UTR443169442924PMID:21511999
three_prime_UTR443169442924PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00226 IPR001623 Pfam DnaJ domain 86 147 24
PF01556 IPR002939 Pfam Chaperone DnaJ, C-terminal 368 445 5
PF00684 IPR001305 Pfam Heat shock protein DnaJ, cysteine-rich domain 240 303 4
SM00271 IPR001623 SMART DnaJ domain 85 142 25
PS50076 IPR001623 Prosite Profiles DnaJ domain 86 150 24
PS51188 IPR001305 Prosite Profiles Heat shock protein DnaJ, cysteine-rich domain 227 308 4
PS00636 IPR018253 Prosite Patterns DnaJ domain 127 146 14
G3DSA:2.60.260.20 Gene3D 359 437 5
G3DSA:2.60.260.20 Gene3D 307 357 5
G3DSA:2.60.260.20 Gene3D 210 234 5
G3DSA:1.10.287.110 IPR001623 Gene3D 78 171 26
G3DSA:2.10.230.10 IPR001305 Gene3D 235 306 4
SSF57938 IPR001305 SuperFamily 227 307 4
SSF46565 IPR001623 SuperFamily 81 182 25
SSF49493 IPR008971 SuperFamily 309 367 5
SSF49493 IPR008971 SuperFamily 362 447 5
SSF49493 IPR008971 SuperFamily 210 245 5
PR00625 IPR003095 PRINTS DnaJ domain 142 161 21
PR00625 IPR003095 PRINTS DnaJ domain 122 142 21
PR00625 IPR003095 PRINTS DnaJ domain 88 106 21
PR00625 IPR003095 PRINTS DnaJ domain 106 121 21
PTHR24076 hmmpanther 85 451 4

View domain organization at Pfam

Protein Properties

Ave. residue weight 108.31 Da
Charge 27.00
Isoelectric point 9.83
Molecular weight 57.19 kDa
Number of residues 528
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide3028.28PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide7017.37PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.57PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide2.8PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPCC4G3.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC4G3.14 Retrieval of eukaryotic orthologs
BioGrid SPCC4G3.14 BioGRID Interaction Datasets
Bähler Lab SPCC4G3.14 Cell Cycle Expression Profile
Bähler Lab SPCC4G3.14 Meiosis/Sporulation Expression Profies
Bähler Lab SPCC4G3.14 Pheromone response/mating expression profiles
Bähler Lab SPCC4G3.14 Environmental stress expression profiles
Bähler Lab SPCC4G3.14 Bähler Lab Transcriptome Viewer
Cyclebase SPCC4G3.14 Cell Cycle Data
PInt SPCC4G3.14 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC4G3.14 Entrez Gene
WikiGene2539501DNAJ domain protein Mdj1 (predicted)
Uniprot_genenameMDJ1
EntrezGene2539501DNAJ domain protein Mdj1 (predicted)
UniProtKB/SwissProtP87239DnaJ homolog 1, mitochondrial
ModBaseP87239Database of comparative protein structure models
Pfam Protein DomainsP87239Pfam Domain Arrangement
RefSeq PeptideNP_587824DNAJ domain protein Mdj1 (predicted)
RefSeq mRNANM_001022817972h- DNAJ domain protein Mdj1 (predicted) (mdj1), mRNA
European Nucleotide ArchiveCAB09769ENA Protein Mapping
SPD / RIKEN25/25E10Orfeome Localization Data
UniParcUPI0000069F2DUniProt Archive

Literature for mdj1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013