ght8 (SPCC548.06c)


Gene Standard Nameght8 Characterisation Statusbiological_role_inferred
Systematic IDSPCC548.06c Feature Typeprotein coding
Synonyms Name Description
Producthexose transporter Ght8 (predicted) Product Size547aa, 60.18 kDa
Genomic Location Chromosome III, 230546-226336 (4211nt); CDS:228400-226757 (1644nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015149hexose transmembrane transporter activityTASPMID:107358576
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0035428hexose transmembrane transportTASPMID:107358578
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005887integral component of plasma membraneTASPMID:1073585749
GO:0005739mitochondrionIEAUniProtKB-KW:KW-0496GO_REF:0000037758
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyght8ΔNullPECO:0000005, PECO:0000137PMID:236978063760
Microscopyght8ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001Microscopyght8ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1230546226336

UTRs

Region Coordinates Reference
five_prime_UTR230546..228401PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 General substrate transporter 11 467 15
TMhelix TMHMM 429 451 959
TMhelix TMHMM 368 390 959
TMhelix TMHMM 145 167 959
TMhelix TMHMM 180 199 959
TMhelix TMHMM 118 135 959
TMhelix TMHMM 331 353 959
TMhelix TMHMM 403 425 959
TMhelix TMHMM 89 111 959
TMhelix TMHMM 7 29 959
TMhelix TMHMM 304 326 959
PS00216 Prosite Patterns IPR005829 Sugar transporter, conserved site 318 335 15
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 55
PTHR24063 HMMPANTHER 4 496 11
PTHR24063:SF337 HMMPANTHER 4 496 8
1.20.1250.20 Gene3D 263 457 69
1.20.1250.20 Gene3D 48 204 69
SSF103473 SuperFamily IPR016196 Major facilitator superfamily domain, general substrate transporter 8 464 76
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
TIGR00879 tigrfam IPR003663 Sugar/inositol transporter 6 463 10
SignalP-noTM signalp 1 21 212

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.01 Da
Charge -2.50
Isoelectric point 5.94
Molecular weight 60.18 kDa
Number of residues 547
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS537PMID:217125471663
present during mitotic M phase
S537PMID:24763107
MOD:00696phosphorylated residueNASPMID:195477441915
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
27740.37during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
6575.8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
11514during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
10868during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
11563during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
11694during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
12459during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
24during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
5.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Genome Organisation
DescriptionQualifierReferenceCount
tandem duplication31
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPCC548.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC548.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC548.06c BioGRID Interaction Datasets
Expression Viewer SPCC548.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC548.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC548.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC548.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC548.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC548.06c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC548.06c Cell Cycle Data
GEO SPCC548.06c GEO profiles
PInt SPCC548.06c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2539300hexose transporter Ght8 (predicted)
EntrezGene2539300hexose transporter Ght8 (predicted)
SPD / RIKEN34/34E10Orfeome Localization Data
UniProtKB/SwissProtQ9P3U7Probable high-affinity hexose transporter ght8, mitochondrial
ModBaseQ9P3U7Database of comparative protein structure models
STRINGQ9P3U7Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587746hexose transporter Ght8 (predicted)
RefSeq mRNANM_001022740972h- hexose transporter Ght8 (predicted) (ght8), mRNA
European Nucleotide ArchiveCAB94948ENA Protein Mapping
European Nucleotide ArchiveCAB94948.1ENA Protein Mapping
UniParcUPI000006B938UniProt Archive

Literature for ght8

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014