ght1 (SPCC548.07c)


Gene Standard Nameght1 Characterisation Statuspublished
Systematic IDSPCC548.07c Feature Typeprotein coding
Synonyms Name Description
Producthexose transmembrane transporter Ght1 Product Size557aa, 61.64 kDa
Genomic Location Chromosome III, 235289-232288 (3002nt); CDS:234507-232834 (1674nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
GO Cellular Component
Term NameCount
integral component of plasma membrane49
Annotation ExtensionEvidenceWith/FromReference
plasma membrane255
Annotation ExtensionEvidenceWith/FromReference
plasma membrane of cell tip18
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
normal cell population growth during glucose starvationght1Δ8
normal growth on glucose carbon sourceght1Δ273
viable vegetative cell populationght1Δ3837

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyght1Δ3100

FYPO Multi-allele Phenotypes

Population Phenotype

Term NameGenotypes
decreased cell population growth on glucose carbon sourceght1Δ, ght2Δ, ght5Δ, ght8Δ
ght1Δ, ght5Δ, ght8Δ
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons235289..232288
5' UTR235289..234508PMID:21511999
3' UTR232833..232288PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 Major facilitator, sugar transporter-like 11 467 16
TMhelix TMHMM 404 426 953
TMhelix TMHMM 54 76 953
TMhelix TMHMM 332 354 953
TMhelix TMHMM 143 165 953
TMhelix TMHMM 433 452 953
TMhelix TMHMM 266 288 953
TMhelix TMHMM 89 111 953
TMhelix TMHMM 300 322 953
TMhelix TMHMM 367 389 953
TMhelix TMHMM 178 200 953
TMhelix TMHMM 7 29 953
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 55
PTHR23500 HMMPANTHER 5 522 10
PTHR23500:SF131 HMMPANTHER 5 522 8
1.20.1250.20 Gene3D Major facilitator superfamily domain 261 457 72
1.20.1250.20 Gene3D Major facilitator superfamily domain 48 204 72
SSF103473 SuperFamily IPR020846 Major facilitator superfamily domain 7 465 76
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
TIGR00879 TIGRFAM IPR003663 Sugar/inositol transporter 5 463 10
SignalP-noTM signalp 1 21 207

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.66 Da
Charge 1.00
Codon Adaptation Index 0.57
Isoelectric point 6.74
Molecular weight 61.64 kDa
Number of residues 557
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelpresent during GO:0071333Northern assay evidencePMID:9090050
increased during GO:0071456expression microarray evidencePMID:22235339

Quantitative Gene Expression

View graphical display of gene expression data for ght1 (SPCC548.07c)

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.8during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
1.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4605
conserved in eukaryotes4515
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPCC548.07c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withemp70EMP70 family endosomal transport protein Emp70 Positive GeneticPMID:22681890
negative genetic interaction withSPBPB10D8.02carylsulfatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withvps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC548.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC548.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC548.07c BioGRID Interaction Datasets
Expression Viewer SPCC548.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC548.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC548.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC548.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC548.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC548.07c Transcriptome Viewer (Bähler Lab)
GEO SPCC548.07c GEO profiles
PInt SPCC548.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC548.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC548.07c Fission yeast phenotypic data & analysis
Cyclebase SPCC548.07c.1 Cell Cycle Data
SPD / RIKEN35/35A08Orfeome Localization Data
UniProtKB/SwissProtQ9P3U6High-affinity glucose transporter ght1
ModBaseQ9P3U6Database of comparative protein structure models
STRINGQ9P3U6Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587747hexose transporter Ght1
RefSeq mRNANM_001022741972h- hexose transporter Ght1 (ght1), mRNA

Literature for ght1

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016