ght1 (SPCC548.07c)

Gene Standard Nameght1 Characterisation Statuspublished
Systematic IDSPCC548.07c Feature Typeprotein coding
Synonyms Name Description
Producthexose transmembrane transporter Ght1 Product Size557aa, 61.64 kDa
Genomic Location Chromosome III, 235289-232288 (3002nt); CDS:234507-232834 (1674nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
GO Cellular Component
Term NameCount
integral component of plasma membrane48
Annotation ExtensionEvidenceWith/FromReference
plasma membrane256
Annotation ExtensionEvidenceWith/FromReference
plasma membrane of cell tip19
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
normal cell population growth during glucose starvationght1Δ8
normal growth on glucose carbon sourceght1Δ318
viable vegetative cell populationght1Δ3862

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyght1Δ3103

FYPO Multi-allele Phenotypes

Population Phenotype

Term NameGenotypes
decreased cell population growth on glucose carbon sourceght5Δ, ght8Δ, ght1Δ, ght2Δ
ght5Δ, ght1Δ, ght8Δ
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR235289..234508PMID:21511999
3' UTR232833..232288PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 Major facilitator, sugar transporter-like 11 467 15
TMhelix TMHMM 332 354 950
TMhelix TMHMM 143 165 950
TMhelix TMHMM 300 322 950
TMhelix TMHMM 266 288 950
TMhelix TMHMM 89 111 950
TMhelix TMHMM 367 389 950
TMhelix TMHMM 178 200 950
TMhelix TMHMM 7 29 950
TMhelix TMHMM 433 452 950
TMhelix TMHMM 404 426 950
TMhelix TMHMM 54 76 950
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 53
PTHR23500:SF131 HMMPANTHER 5 522 8
PTHR23500 HMMPANTHER 5 522 10
1.20.1250.20 Gene3D Glycerate/sugar phosphate transporter, conserved site 261 457 72
1.20.1250.20 Gene3D Glycerate/sugar phosphate transporter, conserved site 48 204 72
SSF103473 SuperFamily IPR020846 Major facilitator superfamily domain 7 465 76
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
TIGR00879 TIGRFAM IPR003663 Sugar/inositol transporter 5 463 10
SignalP-noTM signalp 1 21 207

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.66 Da
Charge 1.00
Codon Adaptation Index 0.57
Isoelectric point 6.74
Molecular weight 61.64 kDa
Number of residues 557
Gene Expression

Qualitative Gene Expression

RNA levelincreased during GO:0071456expression microarray evidencePMID:22235339
present during GO:0071333Northern assay evidencePMID:9090050

Quantitative Gene Expression

View graphical display of gene expression data for ght1 (SPCC548.07c)

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.8during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
1.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
conserved in fungi4608
conserved in eukaryotes4516

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPCC548.07c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withemp70EMP70 family endosomal transport protein Emp70 Positive GeneticPMID:22681890
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withSPBPB10D8.02carylsulfatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction witheso1mitotic cohesin N-acetyltransferase/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
negative genetic interaction withvps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC548.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC548.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC548.07c BioGRID Interaction Datasets
Expression Viewer SPCC548.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC548.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC548.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC548.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC548.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC548.07c Transcriptome Viewer (Bähler Lab)
GEO SPCC548.07c GEO profiles
PInt SPCC548.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC548.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC548.07c Fission yeast phenotypic data & analysis
Cyclebase SPCC548.07c.1 Cell Cycle Data
SPD / RIKEN35/35A08Orfeome Localization Data
UniProtKB/SwissProtQ9P3U6High-affinity glucose transporter ght1
ModBaseQ9P3U6Database of comparative protein structure models
STRINGQ9P3U6Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587747hexose transporter Ght1
RefSeq mRNANM_001022741972h- hexose transporter Ght1 (ght1), mRNA
European Nucleotide Archive-ENA Protein Mapping
European Nucleotide ArchiveCAB94949.1ENA Protein Mapping
UniParcUPI000012B41EUniProt Archive

Literature for ght1

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017