ght1 (SPCC548.07c)

Gene Standard Nameght1 Characterisation Statuspublished
Systematic IDSPCC548.07c Feature Typeprotein coding
Synonyms Name Description
Producthexose transmembrane transporter Ght1 Product Size557aa, 61.64 kDa
Genomic Location Chromosome III, 235289-232288 (3002nt); CDS:234507-232834 (1674nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
GO Cellular Component
Term NameCount
integral component of plasma membrane49
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationght1ΔNull3792

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyght1ΔNull3092
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR235289..234508PMID:21511999
3' UTR232833..232288PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 General substrate transporter 11 467 15
TMhelix TMHMM 178 200 959
TMhelix TMHMM 7 29 959
TMhelix TMHMM 332 354 959
TMhelix TMHMM 433 452 959
TMhelix TMHMM 300 322 959
TMhelix TMHMM 266 288 959
TMhelix TMHMM 54 76 959
TMhelix TMHMM 404 426 959
TMhelix TMHMM 367 389 959
TMhelix TMHMM 143 165 959
TMhelix TMHMM 89 111 959
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 55
PTHR24063 HMMPANTHER 1 493 11
PTHR24063:SF337 HMMPANTHER 1 493 8
1.20.1250.20 Gene3D 48 204 72
1.20.1250.20 Gene3D 261 457 72
SSF103473 SuperFamily IPR020846 Major facilitator superfamily domain 7 465 76
SignalP-noTM signalp 1 21 212
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
TIGR00879 tigrfam IPR003663 Sugar/inositol transporter 5 463 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.66 Da
Charge 1.00
Isoelectric point 6.74
Molecular weight 61.64 kDa
Number of residues 557
Gene Expression

Qualitative Gene Expression

RNA levelpresent during GO:0071333Northern assay evidencePMID:9090050

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.8during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
1.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4604
conserved in eukaryotes4516

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
positive genetic interaction withSPBC1105.08EMP70 family Positive GeneticPMID:22681890
negative genetic interaction withSPBPB10D8.02carylsulfatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC548.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC548.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC548.07c BioGRID Interaction Datasets
Expression Viewer SPCC548.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC548.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC548.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC548.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC548.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC548.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC548.07c Cell Cycle Data
GEO SPCC548.07c GEO profiles
PInt SPCC548.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC548.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC548.07c Fission yeast phenotypic data & analysis
SPD / RIKEN35/35A08Orfeome Localization Data
UniProtKB/SwissProtQ9P3U6High-affinity glucose transporter ght1
ModBaseQ9P3U6Database of comparative protein structure models
STRINGQ9P3U6Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587747hexose transporter Ght1
RefSeq mRNANM_001022741972h- hexose transporter Ght1 (ght1), mRNA
European Nucleotide Archive-ENA Protein Mapping
European Nucleotide ArchiveCAB94949.1ENA Protein Mapping
UniParcUPI000012B41EUniProt Archive

Literature for ght1

Search: Europe PMC or PubMed

Release Version: PomBase:25_50 - 10 Mar 2015