swp1 (SPCC553.06)

Gene Standard Nameswp1 Characterisation Statusbiological role inferred
Systematic IDSPCC553.06 Feature Typeprotein coding
Synonyms Name Description
Productoligosaccharyltransferase delta subunit Swp1 (predicted) Product Size271aa, 29.33 kDa
Genomic Location Chromosome III, 296631-295229 (1403nt); CDS:296487-295482 (1006nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
dolichyl-diphosphooligosaccharide-protein glycotransferase activity7
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
protein N-linked glycosylation30
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum602
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane969
Annotation ExtensionEvidenceWith/FromReference
oligosaccharyltransferase complex8
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationswp1Δ1468

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, single cell division, abnormal cell shapeswp1Δ49
inviable sporeswp1Δ476
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons296631..296357, 296266..296068, 295967..295229
Intron296356..296267, 296067..295968
5' UTR296631..296488PMID:21511999
CDS296487..296357, 296266..296068, 295967..295482
3' UTR295481..295229PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05817 Pfam IPR008814 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 27 256 1
TMhelix TMHMM 186 208 950
TMhelix TMHMM 229 251 950
PTHR12640 HMMPANTHER 6 267 1
SignalP-noTM signalp 1 18 207

View domain organization at Pfam

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 108.23 Da
Charge -2.50
Codon Adaptation Index 0.43
Isoelectric point 5.59
Molecular weight 29.33 kDa
Number of residues 271

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS215 2293
Annotation ExtensionEvidenceResidueReference
IDA S215 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for swp1 (SPCC553.06)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
39568during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
42598during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
3551.81during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
41269during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
9363.19during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
10during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
1.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPCC553.06 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byred5human ZC3H3 homolog Affinity Capture-MSPMID:24713849
External References
Database Identifier Description
NBRP SPCC553.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC553.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC553.06 BioGRID Interaction Datasets
Expression Viewer SPCC553.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC553.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC553.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC553.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC553.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC553.06 Transcriptome Viewer (Bähler Lab)
GEO SPCC553.06 GEO profiles
PInt SPCC553.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC553.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC553.06 Fission yeast phenotypic data & analysis
Cyclebase SPCC553.06.1 Cell Cycle Data
SPD / RIKEN14/14H01Orfeome Localization Data
UniProtKB/SwissProtO74943Uncharacterized protein C553.06
ModBaseO74943Database of comparative protein structure models
STRINGO74943Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587768oligosaccharyltransferase delta subunit Swp1 (predicted)
RefSeq mRNANM_001022761972h- oligosaccharyltransferase delta subunit Swp1 (predicted) (swp1), mRNA
European Nucleotide ArchiveCAA19258.1ENA Protein Mapping
KEGG00510+ biosynthesis
KEGG00513+ types of N-glycan biosynthesis
UniParcUPI000006B04EUniProt Archive

Literature for swp1

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017