swp1 (SPCC553.06)


Gene Standard Nameswp1 Characterisation Statusbiological_role_inferred
Systematic IDSPCC553.06 Feature Typeprotein coding
Synonyms Name Description
Productoligosaccharyltransferase delta subunit Swp1 (predicted) Product Size271aa, 29.33 kDa
Genomic Location Chromosome III, 296631-295229 (1403nt); CDS:296487-295482 (1006nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004579dolichyl-diphosphooligosaccharide-protein glycotransferase activity8
contributes_toISOSGD:S000004757GO_REF:0000024
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006487protein N-linked glycosylationISOSGD:S000004757GO_REF:000002432
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371018
GO:0008250oligosaccharyltransferase complexISOSGD:S000004757GO_REF:00000248
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyswp1ΔNullPMID:204732891338
Microscopyswp1ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002420inviable after spore germination, single cell division, abnormal cell shapeMicroscopyswp1ΔNullPECO:0000005, PECO:0000137PMID:2369780647
FYPO:0002151inviable sporeMicroscopyswp1ΔNullPECO:0000005, PECO:0000137PMID:23697806465
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1296631296357
2296266296068
3295967295229

UTRs

Region Coordinates Reference
five_prime_UTR296631..296488PMID:21511999
three_prime_UTR295481..295229PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05817 Pfam IPR008814 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 30 253 1
TMhelix TMHMM 229 251 959
TMhelix TMHMM 186 208 959
PTHR12640:SF0 HMMPANTHER IPR008814 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 1 267 1
PTHR12640 HMMPANTHER 1 267 1
SignalP-noTM signalp 1 18 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 108.23 Da
Charge -2.50
Isoelectric point 5.59
Molecular weight 29.33 kDa
Number of residues 271
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
39568during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
42598during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
41269during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
3551.81during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
9363.19during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
10during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
1.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
red5human ZC3H3 homolog Affinity Capture-MSPMID:24713849
External References
Database Identifier Description
NBRP SPCC553.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC553.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC553.06 BioGRID Interaction Datasets
Expression Viewer SPCC553.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC553.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC553.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC553.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC553.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC553.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC553.06 Cell Cycle Data
GEO SPCC553.06 GEO profiles
PInt SPCC553.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC553.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC553.06 Fission yeast phenotypic data & analysis
SPD / RIKEN14/14H01Orfeome Localization Data
UniProtKB/SwissProtO74943Uncharacterized protein C553.06
ModBaseO74943Database of comparative protein structure models
STRINGO74943Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587768oligosaccharyltransferase delta subunit Swp1 (predicted)
RefSeq mRNANM_001022761972h- oligosaccharyltransferase delta subunit Swp1 (predicted) (swp1), mRNA
European Nucleotide ArchiveCAA19258.1ENA Protein Mapping
UniParcUPI000006B04EUniProt Archive

Literature for swp1

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014