swp1 (SPCC553.06)

Gene Standard Nameswp1 Characterisation Statusbiological_role_inferred
Systematic IDSPCC553.06 Feature Typeprotein coding
Synonyms Name Description
Productoligosaccharyltransferase delta subunit Swp1 (predicted) Product Size271aa, 29.33 kDa
Genomic Location Chromosome III, 296631-295229 (1403nt); CDS:296487-295482 (1006nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004579dolichyl-diphosphooligosaccharide-protein glycotransferase activity8
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006487protein N-linked glycosylationISOSGD:S000004757GO_REF:000002429
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
GO:0008250oligosaccharyltransferase complexISOSGD:S000004757GO_REF:00000248
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyswp1ΔNullPMID:204732891309
Microscopyswp1ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002420inviable after spore germination, single cell division, abnormal cell shapeMicroscopyswp1ΔNullPECO:0000005, PECO:0000137PMID:2369780646
FYPO:0002151inviable sporeMicroscopyswp1ΔNullPECO:0000005, PECO:0000137PMID:23697806447
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05817 Pfam IPR008814 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 30 253 1
TMhelix TMHMM 186 208 959
TMhelix TMHMM 229 251 959
PTHR12640:SF0 HMMPANTHER IPR008814 1 267 1
PTHR12640 HMMPANTHER 1 267 1
Low complexity (SEG) seg 4 17
Low complexity (SEG) seg 194 207
Low complexity (SEG) seg 215 224
SignalP-noTM signalp 1 18 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 108.23 Da
Charge -2.50
Isoelectric point 5.59
Molecular weight 29.33 kDa
Number of residues 271
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
9363.19during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
3551.81during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
10during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
1.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPCC553.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC553.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC553.06 BioGRID Interaction Datasets
Expression Viewer SPCC553.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC553.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC553.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC553.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC553.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC553.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC553.06 Cell Cycle Data
GEO SPCC553.06 GEO profiles
PInt SPCC553.06 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2539265oligosaccharyltransferase subunit
EntrezGene2539265oligosaccharyltransferase subunit
SPD / RIKEN14/14H01Orfeome Localization Data
UniProtKB/SwissProtO74943Uncharacterized protein C553.06
ModBaseO74943Database of comparative protein structure models
StringO74943Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587768oligosaccharyltransferase subunit
RefSeq mRNANM_001022761972h- oligosaccharyltransferase subunit (SPCC553.06), mRNA
European Nucleotide ArchiveCAA19258ENA Protein Mapping
UniParcUPI000006B04EUniProt Archive

Literature for swp1

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014