taf5 (SPCC5E4.03c)

Gene Standard Nametaf5 ChromosomeIII
Systematic IDSPCC5E4.03c Gene Start642561
Synonymstaf72 Gene End640083
ProductSAGA complex subunit/TATA-binding protein associated factor/transcription factor TFIID complex subunit Taf5 Gene Length2479
Feature Typeprotein coding CDS Start642444
Name Description CDS End640145
Characterisation Statuspublished CDS Length2300

Ensembl Gene Location
  1. mug111
  2. sec231
  3. ccr4
  4. SPNCRNA.1148
  5. taf5
  6. cut1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationno_name (unrecorded)unrecordedPMID:11279037
Microscopytaf5delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005515protein binding
requires_sequence_feature Pfam:PF00400IPItaf6PMID:11972332
requires_sequence_feature Pfam:PF04494IPItaf6PMID:11972332
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006338chromatin remodelingICGO:0000124GO_REF:0000001
GO:0006355regulation of transcription, DNA-dependentIEAUniProtKB:KW-0805GO_REF:0000037
GO:0006367transcription initiation from RNA polymerase II promoterICGO:0005669GO_REF:0000001
GO:0016573histone acetylationICGO:0000124GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000124SAGA complexIDAPMID:11972332
IDAPMID:19056896
GO:0005634nucleusIDAPMID:16823372
GO:0005669transcription factor TFIID complexIDAPMID:11972332
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1642561642138
2641924640831
3640774640606
4640556640292
5640241640083

References

Region Start End Reference
three_prime_UTR640144640083PMID:21511999
three_prime_UTR640144640083PMID:21511999
five_prime_UTR642561642445PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF04494 IPR007582 Pfam TFIID subunit, WD40-associated region 45 184 2
PF08513 IPR013720 Pfam LisH dimerisation motif, subgroup 10 36 8
PF00400 IPR001680 Pfam WD40 repeat 455 491 104
PF00400 IPR001680 Pfam WD40 repeat 375 407 104
PF00400 IPR001680 Pfam WD40 repeat 497 533 104
PF00400 IPR001680 Pfam WD40 repeat 414 449 104
PF00400 IPR001680 Pfam WD40 repeat 540 575 104
PF00400 IPR001680 Pfam WD40 repeat 315 352 104
SM00320 IPR001680 SMART WD40 repeat 369 407 120
SM00320 IPR001680 SMART WD40 repeat 410 449 120
SM00320 IPR001680 SMART WD40 repeat 536 575 120
SM00320 IPR001680 SMART WD40 repeat 452 491 120
SM00320 IPR001680 SMART WD40 repeat 313 352 120
SM00320 IPR001680 SMART WD40 repeat 494 533 120
SM00667 IPR006594 SMART LisH dimerisation motif 8 40 11
PS50294 IPR017986 Prosite Profiles WD40-repeat-containing domain 320 584 104
PS50896 IPR006594 Prosite Profiles LisH dimerisation motif 8 40 11
PS50082 IPR001680 Prosite Profiles WD40 repeat 320 361 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 543 576 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 501 542 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 459 500 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 417 449 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 375 416 100
PS00678 IPR019775 Prosite Patterns WD40 repeat, conserved site 478 492 65
PS00678 IPR019775 Prosite Patterns WD40 repeat, conserved site 562 576 65
G3DSA:2.130.10.10 IPR015943 Gene3D 313 601 144
SSF160897 SuperFamily 45 188 2
SSF50978 IPR017986 SuperFamily 312 617 135
PR00320 IPR020472 PRINTS G-protein beta WD-40 repeat 478 492 43
PR00320 IPR020472 PRINTS G-protein beta WD-40 repeat 562 576 43
PR00320 IPR020472 PRINTS G-protein beta WD-40 repeat 394 408 43
PTHR19879:SF0 hmmpanther 10 642 2
PTHR19879 hmmpanther 10 642 2

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190

Protein Properties

Ave. residue weight 112.57 Da
Charge 0.00
Isoelectric point 6.51
Molecular weight 72.38 kDa
Number of residues 643
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2382.38PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide4263.44PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.92PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide3.7PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ubc11ubiquitin conjugating enzyme E2-C, Ubc11 Dosage RescuePMID:11279037
cut9anaphase-promoting complex subunit Cut9 Dosage RescuePMID:11279037
get1GET complex subunit Get1 (predicted) Negative GeneticPMID:22681890
atg14autophagy specific phophatidylinositol 3-kinase complex subunit Atg14 (predicted) Negative GeneticPMID:22681890
gcd10tRNA (m1A) methyltransferase, translation initiation factor eIF-3 gamma subunit Gcd10 (predicted) Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Affinity Capture-WesternPMID:11279037
taf6histone H4-like TAF Taf6, SAGA complex subunit Reconstituted ComplexPMID:11972332
Two-hybrid
Affinity Capture-Western
spt7SAGA complex bromodomain subunit Spt7 Affinity Capture-MSPMID:19056896
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
tfg3transcription factor TFIIF complex subunit Tfg3 Affinity Capture-WesternPMID:15616156
tra1SAGA complex phosphatidylinositol pseudokinase Tra1 Affinity Capture-MSPMID:21642955
tbp1TATA-binding protein (TBP) Affinity Capture-WesternPMID:11279037
Affinity Capture-WesternPMID:11972332
ada1adenosine deaminase Ada1 (predicted) Affinity Capture-MSPMID:21642955
taf111transcription factor TFIID complex subunit Taf111 Affinity Capture-WesternPMID:11279037
Affinity Capture-WesternPMID:11972332
hfi1SAGA complex subunit Hfi1 Affinity Capture-MSPMID:19056896
ptr6transcription factor TFIID complex subunit Taf7 Affinity Capture-WesternPMID:11279037
Affinity Capture-WesternPMID:11972332
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External References
Database Identifier Description
NBRP SPCC5E4.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC5E4.03c Retrieval of eukaryotic orthologs
BioGrid SPCC5E4.03c BioGRID Interaction Datasets
Bähler Lab SPCC5E4.03c Cell Cycle Expression Profile
Bähler Lab SPCC5E4.03c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC5E4.03c Pheromone response/mating expression profiles
Bähler Lab SPCC5E4.03c Environmental stress expression profiles
Bähler Lab SPCC5E4.03c Bähler Lab Transcriptome Viewer
Cyclebase SPCC5E4.03c Cell Cycle Data
PInt SPCC5E4.03c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC5E4.03c Entrez Gene
EntrezGene2539353transcription initiation factor TFIID subunit 5
Uniprot_genenameTAF5
WikiGene2539353transcription initiation factor TFIID subunit 5
UniProtKB/SwissProtO13282Transcription initiation factor TFIID subunit 5
ModBaseO13282Database of comparative protein structure models
Pfam Protein DomainsO13282Pfam Domain Arrangement
RefSeq PeptideNP_587902transcription initiation factor TFIID subunit 5
RefSeq mRNANM_001022894972h- transcription initiation factor TFIID subunit 5 (taf5), mRNA
European Nucleotide ArchiveBAA22162ENA Protein Mapping
European Nucleotide ArchiveCAA21958ENA Protein Mapping
SPD / RIKEN38/38B09Orfeome Localization Data
UniParcUPI00001367E4UniProt Archive

Literature for taf5
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013