Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPCC613.03 Feature Typeprotein coding
Synonyms Name Description
Productconserved fungal protein Product Size189aa, 22.48 kDa
Genomic Location Chromosome III, 85128-88460 (3333nt); CDS:85363-85932 (570nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
calcium ion binding44
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
endoplasmic reticulum595
Annotation ExtensionEvidenceWith/FromReference
endoplasmic reticulum lumen13
Annotation ExtensionEvidenceWith/FromReference
Golgi apparatus357
Annotation ExtensionEvidenceWith/FromReference
Golgi lumen2
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to hydroxyureaSPCC613.03ΔNull518
sensitive to methyl methanesulfonateSPCC613.03ΔNull227
sensitive to tacrolimus81
expressivity FYPO_EXT:0000002SPCC613.03ΔNull
viable vegetative cell populationSPCC613.03ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphology3092
penetrance FYPO_EXT:0000001SPCC613.03ΔNull
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PS00018 Prosite Patterns IPR018247 EF-Hand 1, calcium-binding site 87 99 12
PS50222 Prosite Profiles IPR002048 EF-hand domain 74 109 20
PTHR19237 HMMPANTHER 20 186 1 Gene3D IPR011992 EF-hand domain pair 26 105 20
SSF47473 SuperFamily 24 104 21
SignalP-noTM signalp 1 20 212

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000276EF handTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000276

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 118.92 Da
Charge -6.00
Isoelectric point 5.68
Molecular weight 22.48 kDa
Number of residues 189
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
14734during GO:0000080PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
15566during GO:0000084PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
13528during GO:0000085PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
14820during GO:0000087PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
6858.31during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
14169during GO:0072690PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
4972.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
0.57during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi only619
conserved in fungi4604
conserved in eukaryotes4516

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
chk1Chk1 protein kinase Two-hybridPMID:17502373
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
ace2transcription factor Ace2 Positive GeneticPMID:22681890
swc5Swr1 complex subunit Swc5 Negative GeneticPMID:22681890
psy2protein phosphatase PP4 complex subunit Psy2 (predicted) Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Positive GeneticPMID:22681890
rpl160160S ribosomal protein L13/L16 (predicted) Positive GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
sts5RNB-like protein Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Negative GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
pht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
xap5xap-5-like protein Negative GeneticPMID:24957674
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
pof9F-box protein Pof9 Positive GeneticPMID:22681890
myp2myosin II heavy chain Myo3 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC613.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC613.03 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC613.03 BioGRID Interaction Datasets
Expression Viewer SPCC613.03 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC613.03 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC613.03 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC613.03 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC613.03 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC613.03 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC613.03 Cell Cycle Data
GEO SPCC613.03 GEO profiles
PInt SPCC613.03 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC613.03 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC613.03 Fission yeast phenotypic data & analysis
SPD / RIKEN06/06A08Orfeome Localization Data
UniProtKB/SwissProtO74903Uncharacterized calcium-binding protein C613.03
ModBaseO74903Database of comparative protein structure models
STRINGO74903Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587691conserved fungal protein
RefSeq mRNANM_001022686972h- conserved fungal protein (SPCC613.03), mRNA
European Nucleotide ArchiveCAA21055.1ENA Protein Mapping
UniParcUPI000006AF6CUniProt Archive

Literature for SPCC613.03

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015