tti1 (SPCC622.13c)

Gene Standard Nametti1 ChromosomeIII
Systematic IDSPCC622.13c Gene Start1425868
Synonyms Gene End1421146
ProductTel Two Interacting protein 1 Gene Length4723
Feature Typeprotein coding CDS Start1425846
Name Description CDS End1422550
Characterisation Statuspublished CDS Length3297

Ensembl Gene Location
  1. SPCC622.10c
  2. SPCC622.11
  3. gdh1
  4. tti1
  5. SPNCRNA.1195
  6. SPNCRNA.493
  7. SPCC622.14
  8. SPCC622.15c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopytti1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005515protein bindingIPItel2PMID:18076573
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006338chromatin remodelingIPIPMID:19040720
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIEASL-0086GO_REF:0000039
GO:0070209ASTRA complexIDAPMID:19040720
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
114258681421146

References

Region Start End Reference
three_prime_UTR14225491421146PMID:21511999
three_prime_UTR14225491421146PMID:21511999
five_prime_UTR14258681425847PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
SSF48371 IPR016024 SuperFamily 394 647 130
SSF48371 IPR016024 SuperFamily 804 924 130
SSF48371 IPR016024 SuperFamily 292 366 130
SSF48371 IPR016024 SuperFamily 89 162 130
PIRSF005250 IPR016441 PIRSF Uncharacterised conserved protein UCP005250 1 1034 1
PTHR18460 hmmpanther 1 1072 2
PTHR18460:SF3 hmmpanther 1 1072 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000328HEAT repeatTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000328

Protein Properties

Ave. residue weight 113.63 Da
Charge -9.50
Isoelectric point 5.84
Molecular weight 124.76 kDa
Number of residues 1098
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide577.99PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.57PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.3PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
tel2Tel2/Rad-5/Clk-2 family protein Tel2 Affinity Capture-MSPMID:20801936
Affinity Capture-MSPMID:18076573
tor2phosphatidylinositol kinase Tor2 Affinity Capture-MSPMID:18076573
tra1SAGA complex phosphatidylinositol pseudokinase Tra1 Affinity Capture-MSPMID:21642955
tor1phosphatidylinositol kinase Tor1 Affinity Capture-MSPMID:18076573
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External References
Database Identifier Description
NBRP SPCC622.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC622.13c Retrieval of eukaryotic orthologs
BioGrid SPCC622.13c BioGRID Interaction Datasets
Bähler Lab SPCC622.13c Cell Cycle Expression Profile
Bähler Lab SPCC622.13c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC622.13c Pheromone response/mating expression profiles
Bähler Lab SPCC622.13c Environmental stress expression profiles
Bähler Lab SPCC622.13c Bähler Lab Transcriptome Viewer
Cyclebase SPCC622.13c Cell Cycle Data
PInt SPCC622.13c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC622.13c Entrez Gene
EntrezGene2539480Tel Two Interacting protein 1
Uniprot_genenameTTI1
WikiGene2539480Tel Two Interacting protein 1
SPD / RIKEN48/48B09Orfeome Localization Data
UniProtKB/SwissProtO94600TEL2-interacting protein 1
ModBaseO94600Database of comparative protein structure models
Pfam Protein DomainsO94600Pfam Domain Arrangement
RefSeq PeptideNP_588185Tel Two Interacting protein 1
RefSeq mRNANM_001023175972h- Tel Two Interacting protein 1 (tti1), mRNA
European Nucleotide ArchiveCAA21869ENA Protein Mapping
UniParcUPI000006C7CBUniProt Archive

Literature for tti1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013