vph2 (SPCC757.10)


Gene Standard Namevph2 Characterisation Statusbiological_role_inferred
Systematic IDSPCC757.10 Feature Typeprotein coding
Synonyms Name Description
Productendoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Product Size213aa, 24.24 kDa
Genomic Location Chromosome III, 68088-69479 (1392nt); CDS:68531-69235 (705nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
proton-transporting V-type ATPase complex assembly6
Annotation ExtensionEvidenceWith/FromReference
vacuolar acidification17
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum596
Annotation ExtensionEvidenceWith/FromReference
integral component of endoplasmic reticulum membrane68
Annotation ExtensionEvidenceWith/FromReference
vacuole185
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationvph2ΔNull1428
sensitive to doxorubicinvph2ΔNull91

Cell Phenotype

Term NameAlleleExpressionCount
abnormal mitotic cell cyclevph2ΔNull808
inviable elongated vegetative cellvph2ΔNull407
inviable vegetative cell, abnormal cell shape, normal cell sizevph2ΔNull199
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
16808868953
26901769479

UTRs

Region Coordinates Reference
five_prime_UTR68088..68530PMID:21511999
three_prime_UTR69236..69479PMID:21511999
mRNA68088..69479
exon68531..68953,69017..69235
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11712 Pfam IPR021013 ATPase, vacuolar ER assembly factor, Vma12 95 167 1
TMhelix TMHMM 143 165 959
TMhelix TMHMM 117 139 959

View domain organization at Pfam

Protein Properties

Ave. residue weight 113.79 Da
Charge 2.50
Isoelectric point 8.05
Molecular weight 24.24 kDa
Number of residues 213
Sequence
Gene Expression

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.5during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.48during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3432
conserved in vertebrates3407
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withadh8alcohol dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withadn2transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withadn3transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
negative genetic interaction withalg12dolichyl pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase Alg12 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withalg6glucosyltransferase Alg6 Negative GeneticPMID:22681890
negative genetic interaction withalg9mannosyltransferase complex subunit Alg9 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withalp14TOG/XMAP14 family protein Alp14 Negative GeneticPMID:18818364
negative genetic interaction withamk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:18818364
negative genetic interaction withamt3ammonium transmembrane transporter Amt3 Negative GeneticPMID:22681890
negative genetic interaction withapm4AP-2 adaptor complex subunit Apm4 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withapn2AP-endonuclease Apn2 Positive GeneticPMID:18818364
positive genetic interaction withapt1adenine phosphoribosyltransferase (APRT) (predicted) Positive GeneticPMID:22681890
positive genetic interaction withare2acyl-coA-sterol acyltransferase Are2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction witharg7argininosuccinate lyase Positive GeneticPMID:22681890
positive genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Positive GeneticPMID:18818364
positive genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Positive GeneticPMID:22681890
negative genetic interaction withash2Ash2-trithorax family protein Negative GeneticPMID:18818364
positive genetic interaction withask1DASH complex subunit Ask1 Positive GeneticPMID:18818364
positive genetic interaction withatg1801WD repeat protein involved in autophagy Atg18a Positive GeneticPMID:22681890
negative genetic interaction withath1ataxin-2 homolog Negative GeneticPMID:22681890
negative genetic interaction withatp15F0-ATPase epsilon subunit (predicted) Negative GeneticPMID:22681890
negative genetic interaction withaut12autophagy associated protein Aut12 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Positive GeneticPMID:18818364
positive genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Positive GeneticPMID:22681890
negative genetic interaction withbun107WD repeat protein, human WDR48 family Bun107 Negative GeneticPMID:18818364
negative genetic interaction withbun62WD repeat protein, human WDR20 family, Bun62 Negative GeneticPMID:22681890
positive genetic interaction withbut2But2 family protein But2 Positive GeneticPMID:22681890
negative genetic interaction withcan1arginine transmembrane transporter Can1 Negative GeneticPMID:22681890
negative genetic interaction withcbp1CENP-B homolog Negative GeneticPMID:18818364
negative genetic interaction withcbs2protein kinase activator (predicted) Negative GeneticPMID:18818364
negative genetic interaction withcch1calcium channel Cch1 Negative GeneticPMID:22681890
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withcgs2cAMP-specific phosphodiesterase Cgs2 Negative GeneticPMID:22681890
positive genetic interaction withcho1phosphatidyl-N-methylethanolamine N-methyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withchs2chitin synthase homolog Chs2 Negative GeneticPMID:22681890
positive genetic interaction withcip2RNA-binding protein Cip2 Positive GeneticPMID:22681890
negative genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:18818364
negative genetic interaction withcrb2DNA repair protein Rad9 homolog, Rhp9 Negative GeneticPMID:22681890
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:18818364
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
negative genetic interaction withcsn5COP9/signalosome complex subunit Csn5 Negative GeneticPMID:18818364
negative genetic interaction withcuf2middle-meiotic transcription factor Cuf2 Negative GeneticPMID:18818364
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
positive genetic interaction withdad2DASH complex subunit Dad2 Positive GeneticPMID:18818364
positive genetic interaction withdad2DASH complex subunit Dad2 Positive GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:18818364
negative genetic interaction withdcr1dicer Negative GeneticPMID:18818364
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:18818364
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
negative genetic interaction withdef1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdep1Sds3-like family protein Dep1 Negative GeneticPMID:22681890
negative genetic interaction withdlc1dynein light chain Dlc1 Negative GeneticPMID:22681890
negative genetic interaction withdlc2dynein light chain Dlc2 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withdoa10ER-localized ubiquitin-protein ligase E3 Doa10 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withdsc1Golgi Dsc E3 ligase complex subunit Dsc1 Positive GeneticPMID:21504829
positive genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
positive genetic interaction withdsc4Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
negative genetic interaction withdsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
negative genetic interaction withelp2elongator complex subunit Elp2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp6elongator complex subunit Elp6 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withemc1ER membrane protein complex subunit Emc1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction witheme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
negative genetic interaction witheme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:22681890
negative genetic interaction witherp2COPII-coated vesicle component Erp2/3/4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withers1RNA-silencing factor Ers1 Negative GeneticPMID:18818364
positive genetic interaction withetf1electron transfer flavoprotein alpha subunit EtfA (predicted) Positive GeneticPMID:22681890
negative genetic interaction withexg1glucan 1,6-beta-glucosidase Exg1 Negative GeneticPMID:22681890
negative genetic interaction withfep1iron-sensing transcription factor Fep1 Negative GeneticPMID:22681890
negative genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:22681890
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
positive genetic interaction withfma1methionine aminopeptidase Fma1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withfrp1ferric-chelate reductase Frp1 Negative GeneticPMID:22681890
negative genetic interaction withfsv1SNARE Fsv1 Negative GeneticPMID:22681890
positive genetic interaction withftp105Ubp5 interacting protein Ftp105 Positive GeneticPMID:18818364
negative genetic interaction withgal1galactokinase Gal1 Negative GeneticPMID:22681890
positive genetic interaction withgcd10tRNA (m1A) methyltransferase Gcd10 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:18818364
negative genetic interaction withgdh1NADP-specific glutamate dehydrogenase Gdh1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgef1Cdc42 RhoGEF Gef1 Negative GeneticPMID:22681890
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgmh4alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgmh5alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgpa2heterotrimeric G protein alpha-2 subunit Gpa2 Negative GeneticPMID:22681890
negative genetic interaction withgpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
negative genetic interaction withgrx3monothiol glutaredoxin Grx3 Negative GeneticPMID:22681890
negative genetic interaction withgut2glycerol-3-phosphate dehydrogenase Gut2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgyp1GTPase activating protein Gyp1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withhat1histone acetyltransferase Hat1 Positive GeneticPMID:22681890
negative genetic interaction withhhp2serine/threonine protein kinase Hhp2 Negative GeneticPMID:18818364
positive genetic interaction withhip4histone promoter control protein Hip4 Positive GeneticPMID:18818364
negative genetic interaction withhis7phosphoribosyl-AMP cyclohydrolase/phosphoribosyl- ATP pyrophosphohydrolase His7 Negative GeneticPMID:22681890
negative genetic interaction withhmt1vacuolar transmembrane transporter Hmt1 Negative GeneticPMID:22681890
negative genetic interaction withhob3BAR adaptor protein Hob3 Negative GeneticPMID:22681890
negative genetic interaction withhos2histone deacetylase (class I) Hos2 Negative GeneticPMID:22681890
positive genetic interaction withhrp1ATP-dependent DNA helicase Hrp1 Positive GeneticPMID:18818364
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:18818364
positive genetic interaction withhsp104heat shock protein Hsp104 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withhta1histone H2A alpha Positive GeneticPMID:22681890
positive genetic interaction withies2Ino80 complex subunit Ies2 Positive GeneticPMID:18818364
negative genetic interaction withiwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:22681890
negative genetic interaction withlag1sphingosine N-acyltransferase Lag1 Negative GeneticPMID:22681890
negative genetic interaction withleu32-isopropylmalate synthase Leu3 Negative GeneticPMID:22681890
negative genetic interaction withliz1pantothenate transmembrane transporter Liz1 Negative GeneticPMID:22681890
negative genetic interaction withlos1karyopherin exportin T Los1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:18818364
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:22681890
negative genetic interaction withlys4homocitrate synthase Negative GeneticPMID:22681890
negative genetic interaction withmad1mitotic spindle checkpoint protein Mad1 Negative GeneticPMID:18818364
negative genetic interaction withmad1mitotic spindle checkpoint protein Mad1 Negative GeneticPMID:22681890
positive genetic interaction withmad2mitotic spindle checkpoint protein Mad2 Positive GeneticPMID:22681890
positive genetic interaction withmal1maltase alpha-glucosidase Mal1 Positive GeneticPMID:22681890
negative genetic interaction withmde5alpha-amylase homolog Mde5 Negative GeneticPMID:22681890
positive genetic interaction withmed13mediator complex subunit Srb9 Positive GeneticPMID:18818364
positive genetic interaction withmed13mediator complex subunit Srb9 Positive GeneticPMID:22681890
negative genetic interaction withmed20mediator complex subunit Med20 Negative GeneticPMID:18818364
negative genetic interaction withmed6mediator complex subunit Med6 Negative GeneticPMID:18818364
negative genetic interaction withmei2RNA-binding protein involved in meiosis Mei2 Negative GeneticPMID:22681890
negative genetic interaction withmei4meiotic forkhead transcription factor Mei4 Negative GeneticPMID:18818364
negative genetic interaction withmet16phosphoadenosine phosphosulfate reductase Negative GeneticPMID:22681890
negative genetic interaction withmeu22amino acid transmembrane transporter, predicted Meu22 Negative GeneticPMID:22681890
negative genetic interaction withmeu27UPF0300 family protein 5 Negative GeneticPMID:22681890
negative genetic interaction withmga2IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Negative GeneticPMID:18818364
negative genetic interaction withmga2IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmms19Dos2 silencing complex subunit Mms19 Negative GeneticPMID:18818364
negative genetic interaction withmoe1translation initiation factor eIF3d Moe1 Negative GeneticPMID:22681890
negative genetic interaction withmpd2GYF domain protein Negative GeneticPMID:22681890
negative genetic interaction withmsd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
negative genetic interaction withmsn5karyopherin (predicted) Negative GeneticPMID:18818364
positive genetic interaction withmug10Rho guanine nucleotide exchange factor (predicted) Positive GeneticPMID:22681890
negative genetic interaction withmug113T5orf172 family protein Negative GeneticPMID:22681890
positive genetic interaction withmug51variant protein kinase 19 family protein Positive GeneticPMID:22681890
positive genetic interaction withnap2nucleosome assembly protein Nap2 Positive GeneticPMID:22681890
negative genetic interaction withnem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
positive genetic interaction withnmt14-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase Nmt1 Positive GeneticPMID:22681890
positive genetic interaction withnro1negative regulator of Ofd1, Nro1 Positive GeneticPMID:22681890
negative genetic interaction withnup124nucleoporin Nup124 Negative GeneticPMID:22681890
positive genetic interaction withnup60nucleoporin Nup60 Positive GeneticPMID:22681890
positive genetic interaction withnxt1mRNA export receptor Nxt1 Positive GeneticPMID:22681890
positive genetic interaction withobr1ubiquitinated histone-like protein Uhp1 Positive GeneticPMID:22681890
positive genetic interaction withoga1Stm1 homolog Oga1 Positive GeneticPMID:22681890
negative genetic interaction withomh6alpha-1,2-mannosyltransferase Omh6 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withopt3OPT oligopeptide transmembrane transporter family protein Opt3 Negative GeneticPMID:22681890
negative genetic interaction withotu2ubiquitin specific cysteine protease, OTU family, Otu2 Negative GeneticPMID:22681890
positive genetic interaction withpab2poly(A) binding protein Pab2 Positive GeneticPMID:18818364
negative genetic interaction withpab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
negative genetic interaction withpac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
negative genetic interaction withpdt1Nramp family manganese ion transmembrane transporter Negative GeneticPMID:22681890
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:18818364
positive genetic interaction withpex5peroxisomal targeting signal receptor Pex5 Positive GeneticPMID:22681890
negative genetic interaction withpfa3palmitoyltransferase Pfa3 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withpfl4cell surface glycoprotein, adhesion molecule (predicted) Positive GeneticPMID:22681890
negative genetic interaction withpgc1phosphatidylglycerol phospholipase C Pgc1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpil2meiotic eisosome BAR domain protein Pil2 Negative GeneticPMID:22681890
positive genetic interaction withpmp3plasma membrane proteolipid Pmp3 Positive GeneticPMID:22681890
negative genetic interaction withpmr1P-type ATPase, calcium transporting Pmr1 Negative GeneticPMID:22681890
negative genetic interaction withpmt1tRNA methyltransferase Pmt1 Negative GeneticPMID:22681890
negative genetic interaction withpng2ING family homolog Png2 Negative GeneticPMID:18818364
negative genetic interaction withpng2ING family homolog Png2 Negative GeneticPMID:22681890
positive genetic interaction withpnk1DNA kinase/phosphatase Pnk1 Positive GeneticPMID:18818364
negative genetic interaction withpof11F-box protein Pof11 Negative GeneticPMID:22681890
negative genetic interaction withpof9F-box protein Pof9 Negative GeneticPMID:22681890
negative genetic interaction withpom1DYRK family protein kinase Pom1 Negative GeneticPMID:18818364
negative genetic interaction withpph3serine/threonine protein phosphatase, PP4 complex subunit Pph3 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withppk14serine/threonine protein kinase Ppk14 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withppk38Ark1/Prk1 family protein kinase Ppk38 Negative GeneticPMID:22681890
negative genetic interaction withppk8serine/threonine protein kinase Ppk8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppm1leucine carboxyl methyltransferase Ppm1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppr5mitochondrial PPR repeat protein Ppr5 Negative GeneticPMID:22681890
positive genetic interaction withppr8mitochondrial PPR repeat protein Ppr8 Positive GeneticPMID:22681890
negative genetic interaction withpsh3ER chaperone SHR3 homologue Psh3 Negative GeneticPMID:22681890
positive genetic interaction withptc3protein phosphatase 2c homolog 3 Positive GeneticPMID:18818364
positive genetic interaction withptf2Mst2 histone acetytransferase acytyltransferase complex subunit Positive GeneticPMID:22681890
negative genetic interaction withptp4phosphatidate cytidylyltransferase Ptp4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withptr2PTR family peptide transmembrane transporter Ptr2 Negative GeneticPMID:22681890
positive genetic interaction withpub3HECT-type ubiquitin-protein ligase E3 Pub3 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withpuf6Puf family RNA-binding protein Puf6 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withpus2tRNA pseudouridine synthase Pus2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpvg2galactose residue biosynthesis protein Pvg2 Negative GeneticPMID:22681890
negative genetic interaction withpxd1structure-specific DNA nuclease regulator Pxd1 Negative GeneticPMID:22681890
negative genetic interaction withpyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
negative genetic interaction withrad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:18818364
negative genetic interaction withrav2RAVE complex subunit Rav2 Negative GeneticPMID:22681890
negative genetic interaction withrcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Negative GeneticPMID:18818364
positive genetic interaction withres2MBF transcription factor complex subunit Res2 Positive GeneticPMID:18818364
negative genetic interaction withrex3exonuclease Rex3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:18818364
negative genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:22681890
positive genetic interaction withrho5Rho family GTPase Rho5 Positive GeneticPMID:22681890
negative genetic interaction withrik1silencing protein Rik1 Negative GeneticPMID:18818364
negative genetic interaction withrng9contractile ring myosin V regulator Rng9 Negative GeneticPMID:22681890
negative genetic interaction withrog1acylglycerol lipase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrox3mediator complex subunit Med19/Rox3 Positive GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
negative genetic interaction withrpb9DNA-directed RNA polymerase II complex subunit Rpb9 Negative GeneticPMID:18818364
negative genetic interaction withrpl200160S ribosomal protein L20a (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrpl240160S ribosomal protein L24 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrpl410160S ribosomal protein L41 Negative GeneticPMID:22681890
negative genetic interaction withrps100140S ribosomal protein S10 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrps340S ribosomal protein S3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrsc1RSC complex subunit Rsc1 Negative GeneticPMID:18818364
negative genetic interaction withrsv2transcription factor Rsv2 Negative GeneticPMID:18818364
negative genetic interaction withsac12inositol polyphosphate phosphatase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withsce3translation initiation factor (predicted) Negative GeneticPMID:22681890
positive genetic interaction withsde2silencing defective protein Sde2 Positive GeneticPMID:22681890
positive genetic interaction withsdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:18818364
negative genetic interaction withsds23PP2A-type phosphatase inhibitor Sds23/Moc1 Negative GeneticPMID:22681890
negative genetic interaction withsec28coatomer epsilon subunit (predicted) Negative GeneticPMID:18818364
negative genetic interaction withsec63ER protein translocation subcomplex subunit Sec63 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsft1SNARE Sft1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
positive genetic interaction withsgf73SAGA complex subunit Sgf73 Positive GeneticPMID:22681890
negative genetic interaction withsif3Sad1 interacting factor Sif3 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withslx1structure-specific endonuclease catalytic subunit Slx1 Positive GeneticPMID:18818364
negative genetic interaction withsnd1RNA-binding protein, involved in chromatin silencing by small RNA, Snd1 Negative GeneticPMID:22681890
negative genetic interaction withsnf30SWI/SNF complex subunit Snf30 Negative GeneticPMID:18818364
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:18818364
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
positive genetic interaction withsnf59SWI/SNF complex subunit Snf59 Positive GeneticPMID:22681890
positive genetic interaction withsnr13-hydroxyisobutyryl-CoA hydrolase snr1 Positive GeneticPMID:22681890
negative genetic interaction withsnt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
negative genetic interaction withsol1SWI/SNF complex subunit Sol1 Negative GeneticPMID:22681890
negative genetic interaction withspa1ornithine decarboxylase antizyme with +1 programmed ribosomal frameshift Spa1 Negative GeneticPMID:22681890
positive genetic interaction withSPAC1093.03inositol polyphosphate phosphatase (predicted) Positive GeneticPMID:18818364
negative genetic interaction withSPAC1296.01cphosphoacetylglucosamine mutase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC12B10.01cHECT-type ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withSPAC12G12.01cSEA complex subunit, ubiquitin-protein ligase E3 Positive GeneticPMID:22681890
negative genetic interaction withSPAC1687.14cEF hand family protein, unknown role Negative GeneticPMID:22681890
negative genetic interaction withSPAC18G6.13Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC1B3.15cvitamin H transmembrane transporter (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC222.14cGTP binding protein Sey1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC227.17cconserved protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC22H10.02conserved fungal protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC23A1.07ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withSPAC27D7.02cGRIP domain protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC29A4.17cmitochondrial FUN14 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC323.03cSchizosaccharomyces specific protein Positive GeneticPMID:18818364
negative genetic interaction withSPAC3A11.04seipin homolog, involved in lipid catabolism (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC3H8.08ctranscription factor (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC4C5.03CTNS domain protein (SMART) Negative GeneticPMID:22681890
negative genetic interaction withSPAC4G8.03cRNA-binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC4G8.04GTPase activating protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC4G9.19DNAJ domain protein DNAJB family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC513.07flavonol reductase/cinnamoyl-CoA reductase family Negative GeneticPMID:22681890
negative genetic interaction withSPAC57A7.09human RNF family homolog Negative GeneticPMID:22681890
negative genetic interaction withSPAC589.03cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC644.13cRab GTPase binding (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC694.04cconserved eukaryotic protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC6B12.04caminotransferase class I and II (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC6C3.06cP-type ATPase, calcium transporting (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC6G9.14RNA-binding protein (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC6G9.15cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC824.09cGTPase activating protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC869.02cnitric oxide dioxygenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC926.02conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC926.06cleucine-rich repeat protein, unknown role Negative GeneticPMID:22681890
positive genetic interaction withSPACUNK4.16calpha,alpha-trehalose-phosphate synthase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAP32A8.02xylose and arabinose reductase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAPB2B4.04cvacuolar calcium transporting P-type ATPase P2 type, Pmc1 Negative GeneticPMID:22681890
positive genetic interaction withSPAPB8E5.08Schizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC1105.13cSchizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC115.03gfo/idh/mocA family oxidoreductase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC1198.03cconserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC1348.03S. pombe specific 5Tm protein family Negative GeneticPMID:22681890
negative genetic interaction withSPBC13E7.03cRNA hairpin binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC1604.03cconserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC1604.12Schizosaccharomyces specific phosphoprotein Negative GeneticPMID:22681890
positive genetic interaction withSPBC1685.04Schizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC16A3.10membrane bound O-acyltransferase, MBOAT (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC16H5.12cconserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:18818364
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
negative genetic interaction withSPBC1778.05chuman LAMTOR2 ortholog Negative GeneticPMID:22681890
positive genetic interaction withSPBC1861.07elongin C (predicted) Positive GeneticPMID:18818364
negative genetic interaction withSPBC215.01GTPase activating protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC21B10.08cantibiotic biosynthesis monooxygenase-like domain (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC24C6.04delta-1-pyrroline-5-carboxylate dehydrogenase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC28F2.08cHRD ubiquitin ligase complex subunit (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC30B4.06cmitochondrial GIDA family tRNA uridine 5-carboxymethylaminomethyl modification enzyme (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC31F10.03ChaC-like protein, predicted cation transport regulator Negative GeneticPMID:22681890
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
positive genetic interaction withSPBC36B7.08cnucleosome assembly protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC3E7.05chuman mitofilin ortholog (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC418.02NatA N-acetyltransferase complex subunit (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC4C3.09acetylglucosaminyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC577.11DUF3074 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC646.08coxysterol binding protein (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC651.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC660.17cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
rescuesSPBC713.07cvacuolar polyphosphatase (predicted) Phenotypic SuppressionPMID:21169418
positive genetic interaction withSPBC800.11inosine-uridine preferring nucleoside hydrolase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC8E4.02cSchizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC8E4.05cfumarate lyase superfamily Negative GeneticPMID:22681890
negative genetic interaction withSPBC947.06cspermidine family transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBP4H10.17ccarboxyl methyl esterase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBP4H10.18cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBPB2B2.09c2-dehydropantoate 2-reductase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBPB2B2.18Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPCC11E10.09calpha-amylase homolog (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC1259.08conserved fungal protein, DUF2457 family Negative GeneticPMID:22681890
positive genetic interaction withSPCC126.12GTP cyclohydrolase I involved in 7,8-dihydroneopterin 3'-triphosphate biosynthesis (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC1281.04pyridoxal reductase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC13B11.02cSchizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPCC1795.10cSed5 Vesicle Protein Svp26 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC550.03cSki complex RNA helicase Ski2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC550.11karyopherin (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC622.15cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC663.15cconserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC70.03cproline dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC70.08cmethyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspd1ribonucleotide reductase (RNR) inhibitor Negative GeneticPMID:22681890
negative genetic interaction withspn2mitotic and meiotic (sporulation) septin Spn2 Negative GeneticPMID:22681890
negative genetic interaction withspo20sec14 cytosolic factor family Sec14 Negative GeneticPMID:22681890
negative genetic interaction withspp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:18818364
negative genetic interaction withspp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:22681890
negative genetic interaction withspt2non-specific DNA binding protein Spt2 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Positive GeneticPMID:18818364
negative genetic interaction withssb3DNA replication factor A subunit Ssb3 Negative GeneticPMID:22681890
negative genetic interaction withssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withstm1G-protein coupled receptor Stm1 Positive GeneticPMID:22681890
negative genetic interaction withsua1sulfate adenylyltransferase Negative GeneticPMID:22681890
negative genetic interaction withsum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:18818364
negative genetic interaction withsum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
negative genetic interaction withswc5Swr1 complex subunit Swc5 Negative GeneticPMID:18818364
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:18818364
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
negative genetic interaction withswd2Set1C complex subunit Swd2.1 Negative GeneticPMID:18818364
negative genetic interaction withswd22WD repeat protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withswd3WD repeat protein Swd3 Negative GeneticPMID:18818364
positive genetic interaction withsyj1inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) Positive GeneticPMID:22681890
negative genetic interaction withsyn1synaptotagmin family C2 domain protein, Syn1 Negative GeneticPMID:22681890
negative genetic interaction withtas3RITS complex subunit 3 Negative GeneticPMID:18818364
negative genetic interaction withtcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:22681890
positive genetic interaction withtco89TORC1 subunit Tco89 Positive GeneticPMID:22681890
negative genetic interaction withtea2kinesin-like protein Tea2 Negative GeneticPMID:22681890
negative genetic interaction withtea5pseudokinase Tea5 Negative GeneticPMID:22681890
negative genetic interaction withtfs1transcription elongation factor TFIIS Negative GeneticPMID:18818364
positive genetic interaction withtos4FHA domain protein Tos4 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withtpp1trehalose-6-phosphate phosphatase Tpp1 Negative GeneticPMID:22681890
positive genetic interaction withtri1triman, ribonuclease involved in priRNA formation Tri1 Positive GeneticPMID:22681890
negative genetic interaction withtrk1potassium ion transmembrane transporter Trk1 Negative GeneticPMID:22681890
positive genetic interaction withtrm12tRNA methyltransferase Trm12 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtrp663TRP-like ion channel (predicted) Negative GeneticPMID:22681890
positive genetic interaction withtwf1twinfilin (predicted) Positive GeneticPMID:22681890
positive genetic interaction withubc6ubiquitin conjugating enzyme E2 Ubc6 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withubp3ubiquitin C-terminal hydrolase Ubp3 Positive GeneticPMID:18818364
positive genetic interaction withubp3ubiquitin C-terminal hydrolase Ubp3 Positive GeneticPMID:22681890
negative genetic interaction withubp4ubiquitin C-terminal hydrolase Ubp4 Negative GeneticPMID:18818364
negative genetic interaction withubp6ubiquitin C-terminal hydrolase Ubp6 Negative GeneticPMID:18818364
positive genetic interaction withuep1ribosomal-ubiquitin fusion protein Ubi2 Positive GeneticPMID:22681890
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withulp1SUMO deconjugating enzyme Ulp1 Negative GeneticPMID:22681890
negative genetic interaction withupf1ATP-dependent RNA helicase Upf1 Negative GeneticPMID:22681890
negative genetic interaction withvht1vitamin H transmembrane transporter Vht1 Negative GeneticPMID:22681890
negative genetic interaction withvps1dynamin family protein Vps1 Negative GeneticPMID:22681890
negative genetic interaction withvps20ESCRT III complex subunit Vps20 Negative GeneticPMID:22681890
negative genetic interaction withvps25ESCRT II complex subunit Vps25 Negative GeneticPMID:22681890
negative genetic interaction withvps38phophatidylinositol 3-kinase complex subunit Vps38 Negative GeneticPMID:22681890
negative genetic interaction withvps68vacuolar sorting protein Vps68 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps901guanyl-nucleotide exchange factor Vps901 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withwis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Negative GeneticPMID:18818364
negative genetic interaction withwos2p23 homolog, predicted co-chaperone Wos2 Negative GeneticPMID:22681890
negative genetic interaction withwtf11wtf element Wtf11 Negative GeneticPMID:22681890
positive genetic interaction withwtf15wtf element Wtf15 Positive GeneticPMID:22681890
negative genetic interaction withwtf21wtf element Wtf21 Negative GeneticPMID:22681890
negative genetic interaction withyar1ribosome biogenesis protein Yar1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withyip5Rab GTPase binding Yip5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:18818364
negative genetic interaction withzds1zds family protein phosphatase type A regulator Zds1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withzrg17cation diffusion family zinc transmembrane transporter Zrg17 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPCC757.10 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC757.10 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC757.10 BioGRID Interaction Datasets
Expression Viewer SPCC757.10 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC757.10 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC757.10 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC757.10 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC757.10 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC757.10 Transcriptome Viewer (Bähler Lab)
Cyclebase SPCC757.10 Cell Cycle Data
GEO SPCC757.10 GEO profiles
PInt SPCC757.10 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC757.10 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC757.10 Fission yeast phenotypic data & analysis
SPD / RIKEN07/07A11Orfeome Localization Data
UniProtKB/SwissProtO74920Vacuolar ATPase assembly integral membrane protein vph2
ModBaseO74920Database of comparative protein structure models
STRINGO74920Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_587685endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted)
RefSeq mRNANM_001022680972h- endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) (vph2), mRNA
European Nucleotide ArchiveCAA21235.2ENA Protein Mapping
UniParcUPI000228F46FUniProt Archive

Literature for vph2

Search: Europe PMC or PubMed

Release Version: PomBase:25_49 - 02 Feb 2015