arg1 (SPCC777.09c)

Gene Standard Namearg1 ChromosomeIII
Systematic IDSPCC777.09c Gene Start1615028
Synonyms Gene End1613047
Productacetylornithine aminotransferase Gene Length1982
Feature Typeprotein coding CDS Start1614897
Name Description CDS End1613324
Characterisation Statuspublished CDS Length1574

Ensembl Gene Location
  1. gtr2
  2. SPCC777.06c
  3. SPNCRNA.1211
  4. omh3
  5. bit61
  6. arg1
  7. ubc12
  8. SPCC777.11
  9. SPCC777.12c
  10. SPCC777.17c
  11. vps35
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000035growth auxotrophic for arginineno_name (unrecorded)unrecordedPMID:17622533
FYPO:0002060viable vegetative cell populationMicroscopyarg1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003992N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activityISSUniProtKB:P18544GO_REF:0000001
GO:0030170pyridoxal phosphate bindingIEAIPR005814, IPR015422, IPR015421GO_REF:0000002
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006538glutamate catabolic processISSUniProtKB:P18544GO_REF:0000001
GO:0006592ornithine biosynthetic processISSUniProtKB:P18544GO_REF:0000001
GO:0042450arginine biosynthetic process via ornithineICGO:0003992GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005739mitochondrionIDAPMID:16823372
GO:0005759mitochondrial matrixISSUniProtKB:P18544GO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
116150281614826
216145771613047

References

Region Start End Reference
three_prime_UTR16133231613047PMID:21511999
three_prime_UTR16133231613047PMID:21511999
five_prime_UTR16150281614898PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00202 IPR005814 Pfam Aminotransferase class-III 58 387 7
PS00600 IPR005814 Prosite Patterns Aminotransferase class-III 260 299 5
G3DSA:3.40.640.10 IPR015421 Gene3D 91 337 31
G3DSA:3.90.1150.10 IPR015422 Gene3D 346 438 23
G3DSA:3.90.1150.10 IPR015422 Gene3D 38 90 23
SSF53383 IPR015424 SuperFamily 47 437 31
PTHR11986:SF19 IPR004636 hmmpanther 38 441 1
PTHR11986 IPR005814 hmmpanther Aminotransferase class-III 38 441 7
TIGR00707 IPR004636 tigrfam Transaminase, Acetylornithine/Succinylornithine family 48 436 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.73 Da
Charge 16.50
Isoelectric point 9.49
Molecular weight 47.51 kDa
Number of residues 441
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide103914.04PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide38160.15PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide3.9PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide19PMID:23101633
Experimental Tools
DescriptionQualifierReference
selectable marker, amino acid auxotroph PMID:17622533
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in bacteria
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
lys3saccharopine dehydrogenase Lys3 Synthetic Growth DefectPMID:20460254
car2ornithine transaminase Car2 Synthetic Growth DefectPMID:20460254
car1arginase Car1 Synthetic Growth DefectPMID:20435771
aru1arginase Aru1 Synthetic Growth DefectPMID:20435771
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
far8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
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External References
Database Identifier Description
NBRP SPCC777.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC777.09c Retrieval of eukaryotic orthologs
BioGrid SPCC777.09c BioGRID Interaction Datasets
Bähler Lab SPCC777.09c Cell Cycle Expression Profile
Bähler Lab SPCC777.09c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC777.09c Pheromone response/mating expression profiles
Bähler Lab SPCC777.09c Environmental stress expression profiles
Bähler Lab SPCC777.09c Bähler Lab Transcriptome Viewer
Cyclebase SPCC777.09c Cell Cycle Data
PInt SPCC777.09c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC777.09c Entrez Gene
IntEnz2.6.1.11
KEGGMAP00220
EntrezGene2538726acetylornithine aminotransferase
Uniprot_genenameARG1
WikiGene2538726acetylornithine aminotransferase
SPD / RIKEN45/45B10Orfeome Localization Data
UniProtKB/SwissProtO74548Probable acetylornithine aminotransferase, mitochondrial
ModBaseO74548Database of comparative protein structure models
Pfam Protein DomainsO74548Pfam Domain Arrangement
RefSeq PeptideNP_588255acetylornithine aminotransferase
RefSeq mRNANM_001023245972h- acetylornithine aminotransferase (arg1), mRNA
European Nucleotide ArchiveBAA13776ENA Protein Mapping
European Nucleotide ArchiveCAA20713ENA Protein Mapping
UniParcUPI000006B10FUniProt Archive

Literature for arg1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013