Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPCC965.10 Feature Typeprotein coding
Synonyms Name Description
Producttranscription factor (predicted) Product Size525aa, 59.80 kDa
Genomic Location Chromosome III, 2302442-2305222 (2781nt); CDS:2302549-2304126 (1578nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
Term NameCount
regulation of transcription from RNA polymerase II promoter289
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
decreased cell population growth on glucose carbon sourceSPCC965.10+ (wild type)393
viable vegetative cell populationSPCC965.10Δ3862

Cell Phenotype

Term NameGenotypesCount
viable elongated vegetative cellSPCC965.10+ (wild type)329
viable vegetative cell with normal cell morphologySPCC965.10Δ3103
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR2302442..2302548PMID:21511999
3' UTR2304127..2305222PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11951 Pfam IPR021858 Fungal transcription factor 155 522 1
PF00172 Pfam IPR001138 Zn(2)-C6 fungal-type DNA-binding domain 20 50 29
SM00066 SMART IPR001138 Zn(2)-C6 fungal-type DNA-binding domain 15 59 31
PS50048 Prosite Profiles IPR001138 Zn(2)-C6 fungal-type DNA-binding domain 20 50 32
PS00463 Prosite Patterns IPR001138 Zn(2)-C6 fungal-type DNA-binding domain 20 48 27 Gene3D IPR001138 Zn(2)-C6 fungal-type DNA-binding domain 13 52 31
SSF57701 SuperFamily IPR001138 Zn(2)-C6 fungal-type DNA-binding domain 11 57 32

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000138zf-fungal Zn(2)-Cys(6) binuclear cluster domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000138

Protein Properties

Ave. residue weight 113.91 Da
Charge 0.50
Codon Adaptation Index 0.39
Isoelectric point 6.63
Molecular weight 59.80 kDa
Number of residues 525
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPCC965.10

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.9during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
1.6during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi only552
conserved in fungi4608
conserved in eukaryotes4516

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPCC965.10 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
affinity captured bypir2zf-C2H2 type zinc finger protein, implicated in RNAi (predicted) Affinity Capture-MSPMID:24713849
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPCC965.10 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Positive GeneticPMID:21504829
External References
Database Identifier Description
NBRP SPCC965.10 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC965.10 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC965.10 BioGRID Interaction Datasets
Expression Viewer SPCC965.10 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC965.10 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC965.10 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC965.10 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC965.10 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC965.10 Transcriptome Viewer (Bähler Lab)
GEO SPCC965.10 GEO profiles
PInt SPCC965.10 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC965.10 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC965.10 Fission yeast phenotypic data & analysis
Cyclebase SPCC965.10.1 Cell Cycle Data
SPD / RIKEN25/25D08Orfeome Localization Data
UniProtKB/SwissProtO59830Uncharacterized transcriptional regulatory protein C965.10
ModBaseO59830Database of comparative protein structure models
STRINGO59830Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_588520transcription factor (predicted)
RefSeq mRNANM_001023509972h- transcription factor (predicted) (SPCC965.10), mRNA
European Nucleotide ArchiveCAA19070.1ENA Protein Mapping
UniParcUPI000006BA3EUniProt Archive

Literature for SPCC965.10

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017