rpl3601 (SPCC970.05)


Gene Standard Namerpl3601 Characterisation Statuspublished
Systematic IDSPCC970.05 Feature Typeprotein coding
Synonymsrpl36-1 Name Description
Product60S ribosomal protein L36 Product Size99aa, 11.26 kDa
Genomic Location Chromosome III, 506920-506350 (571nt); CDS:506875-506415 (461nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation470
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2302
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
slow vegetative cell population growthrpl3601Δ361
viable vegetative cell populationrpl3601Δ3844

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrpl3601Δ3100
Target Of
OntologyRelationshipGeneProduct
GO substrate of ubp4 ubiquitin C-terminal hydrolase Ubp4
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons506920..506654, 506492..506350
Intron506653..506493
mRNA506920..506350
5' UTR506920..506876PMID:21511999
CDS506875..506654, 506492..506415
3' UTR506414..506350PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01158 Pfam IPR000509 Ribosomal protein L36e 4 96 2
PS01190 Prosite Patterns IPR000509 Ribosomal protein L36e 50 60 2
PTHR10114 HMMPANTHER IPR000509 Ribosomal protein L36e 1 99 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 113.77 Da
Charge 20.50
Codon Adaptation Index 0.69
Isoelectric point 12.36
Molecular weight 11.26 kDa
Number of residues 99
Modifications

Protein Modifications

Term NameResidueCount
ubiquitinylated lysineK82 512
Annotation ExtensionEvidenceResidueReference
mass spectrometry evidence K82 PMID:26412298
IDA PMID:26412298
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rpl3601 (SPCC970.05)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3160.42during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
47during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
4.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4606
conserved in eukaryotes4516
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2505
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPCC970.05 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bypab2poly(A) binding protein Pab2 Affinity Capture-MSPMID:19336419
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
affinity captured byair1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
binds DNA-binding domain construct withnap2nucleosome assembly protein Nap2 Two-hybridPMID:26771498
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPCC970.05 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
External References
Database Identifier Description
NBRP SPCC970.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC970.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPCC970.05 BioGRID Interaction Datasets
Expression Viewer SPCC970.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPCC970.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPCC970.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPCC970.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPCC970.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPCC970.05 Transcriptome Viewer (Bähler Lab)
GEO SPCC970.05 GEO profiles
PInt SPCC970.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPCC970.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPCC970.05 Fission yeast phenotypic data & analysis
Cyclebase SPCC970.05.1 Cell Cycle Data
SPD / RIKEN04/04B07Orfeome Localization Data
UniProtKB/SwissProtQ9236560S ribosomal protein L36-A
ModBaseQ92365Database of comparative protein structure models
STRINGQ92365Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_58785060S ribosomal protein L36
RefSeq mRNANM_001022843972h- 60S ribosomal protein L36 (rpl3601), mRNA
European Nucleotide ArchiveD88771ENA EMBL mapping
European Nucleotide ArchiveCAA20698.1ENA Protein Mapping
UniParcUPI0000061AFEUniProt Archive

Literature for rpl3601

Search: Europe PMC or PubMed

Release Version: PomBase:30_60 - 12 May 2016