raf2 (SPCC970.07c)

Gene Standard Nameraf2 ChromosomeIII
Systematic IDSPCC970.07c Gene Start500743
Synonymsclr7, cmc2, dos2 Gene End502880
ProductRik1-associated factor Raf2 Gene Length2138
Feature Typeprotein coding CDS Start500859
Name DescriptionCryptic Loci Regulator,
Delocalization Of Swi6,
Cullin-associated Methyltransferase complex subunit,
Rik1-Associated Factor		 CDS End502769
Characterisation Statuspublished CDS Length1911

Ensembl Gene Location
  1. sec8
  2. SPCC970.08
  3. raf2
  4. SPCC970.06
  5. SPNCRNA.1141
  6. rpl3601
  7. mob2
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopyraf2delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:16040243
GO Molecular Function

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0005515protein bindingIPIpcu4PMID:16157682
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0000070mitotic sister chromatid segregationIMPPMID:16040243
GO:0000122negative regulation of transcription from RNA polymerase II promoter
has_regulation_target tlh2IMPPMID:16407326
has_regulation_target tlh1IMPPMID:16407326
GO:0006348chromatin silencing at telomereIMPPMID:16157682
GO:0030466chromatin silencing at silent mating-type cassetteIMPPMID:16157682
GO:0030702chromatin silencing at centromereIMPPMID:16024659
GO:0031048chromatin silencing by small RNAIMPPMID:16040243
GO:0031494regulation of mating type switchingIMPPMID:16157682
GO:0034613cellular protein localization
has_input swi6IMPPMID:16040243
has_input raf1IMPPMID:16040243
GO:0035391maintenance of chromatin silencing at silent mating-type cassetteNASGO_REF:0000001
GO:0045132meiotic chromosome segregationIMPPMID:16040243
GO:0051572negative regulation of histone H3-K4 methylationIMPPMID:16024659
GO:0051574positive regulation of histone H3-K9 methylationIMPPMID:16024659
GO:0051754meiotic sister chromatid cohesion, centromericIMPPMID:16040243
GO Cellular Component

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16040243
GO:0005737cytoplasmIDAPMID:16040243
GO:0005739mitochondrionIEASL-0173GO_REF:0000039
GO:0031618nuclear centromeric heterochromatinICGO:0043494GO_REF:0000001
GO:0031934mating-type region heterochromatinTASPMID:16157682
GO:0043234protein complexEXPPMID:21725325
GO:0043494CLRC ubiquitin ligase complexIDAPMID:16024659
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1500743502880

References

Region Start End Reference
three_prime_UTR502770502880PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF12047 IPR022702 Pfam DNA (cytosine-5)-methyltransferase 1, replication foci domain 7 147 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000137zinc finger proteinPMID:16024659Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0005166zf-basic zinc fingerPMID:16024659Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0005166

Protein Properties

Ave. residue weight 115.24 Da
Charge 13.00
Isoelectric point 8.37
Molecular weight 73.29 kDa
Number of residues 636
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.22PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide0.86PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC3H8.02sec14 cytosolic factor family phosphatidylinositol transporter (predicted) Negative GeneticPMID:22681890
trt1telomerase reverse transcriptase 1 protein Trt1 Negative GeneticPMID:22681890
SPAC637.06alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:18818364
SPBC26H8.05cserine/threonine protein phosphatase (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
hhp2serine/threonine protein kinase Hhp2 Positive GeneticPMID:22681890
mfm3M-factor precursor Mfm3 Negative GeneticPMID:22681890
ctu1cytosolic thiouridylase subunit Ctu1 Negative GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:22681890
Phenotypic SuppressionPMID:20211136
Positive GeneticPMID:18818364
prw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:21504829
pmc5mediator complex subunit Pmc5 Positive GeneticPMID:18818364
atb2tubulin alpha 2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
apl5AP-3 adaptor complex subunit Apl5 (predicted) Negative GeneticPMID:22681890
rap1telomere binding protein Rap1 Negative GeneticPMID:22681890
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
pek1MAP kinase kinase Pek1 Positive GeneticPMID:22681890
spf38splicing factor Spf38 Negative GeneticPMID:22681890
SPAC4F10.16cP-type ATPase (predicted) Positive GeneticPMID:22681890
SPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
clr3histone deacetylase (class II) Clr3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
fhl1fork head transcription factor Fhl1 Negative GeneticPMID:22681890
elp6elongator complex subunit Elp6 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pmc2mediator complex subunit Pmc2/Med1 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
san1sir antagonist Positive GeneticPMID:22681890
ase1antiparallel microtubule cross-linking factor Ase1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC1919.05Ski complex TPR repeat subunit Ski3 (predicted) Positive GeneticPMID:22681890
SPBC21C3.14csequence orphan Negative GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dep1Sds3-like family protein Dep1 Positive GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Positive GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ura3dihydroorotate dehydrogenase Ura3 Negative GeneticPMID:22681890
set11ribosomal protein lysine methyltransferase Set11 Negative GeneticPMID:22681890
caf1CCR4-Not complex CAF1 family ribonuclease subunit Caf1 Negative GeneticPMID:18818364
mrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
def1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
pzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
SPAC139.01cnuclease, XP-G family (predicted) Positive GeneticPMID:22681890
gpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
Negative GeneticPMID:21504829
nup132nucleoporin Nup132 Positive GeneticPMID:22681890
SPAC9E9.05sequence orphan Negative GeneticPMID:22681890
SPBC36B7.08cnucleosome assembly protein (predicted) Positive GeneticPMID:22681890
rps80140S ribosomal protein S8 (predicted) Negative GeneticPMID:22681890
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Positive GeneticPMID:22681890
Phenotypic SuppressionPMID:20211136
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
Negative GeneticPMID:18818364
qcr6ubiquinol-cytochrome-c reductase complex subunit 8, hinge protein (predicted) Negative GeneticPMID:22681890
rpl430260S ribosomal protein L37a (predicted) Negative GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Negative GeneticPMID:22681890
ist1MVB sorting pathway protein (predicted) Negative GeneticPMID:22681890
whi5cell cycle transcriptional repressor Whi5 (predicted) Negative GeneticPMID:22681890
alp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:18818364
arb1argonaute binding protein 1 Positive GeneticPMID:22681890
ark1aurora-B kinase Ark1 Negative GeneticPMID:22681890
psl1cyclin pho85 family (predicted) Positive GeneticPMID:22681890
ubp3ubiquitin C-terminal hydrolase Ubp3 Positive GeneticPMID:18818364
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
swd3WD repeat protein Swd3 Negative GeneticPMID:18818364
cmk2MAPK-activated protein kinase Cmk2 Negative GeneticPMID:22681890
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC13E7.07sequence orphan Negative GeneticPMID:22681890
tas3RITS complex subunit 3 Phenotypic EnhancementPMID:21060862
Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
epe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pho24-nitrophenylphosphatase Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
lsc1Lsk1 associated cyclin Negative GeneticPMID:22681890
SPBC418.02NatA N-acetyltransferase complex subunit (predicted) Positive GeneticPMID:22681890
ppr8mitochondrial PPR repeat protein Ppr8 Positive GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
rpl90160S ribosomal protein L9 Negative GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
fml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Negative GeneticPMID:18818364
ser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
cmk1calcium/calmodulin-dependent protein kinase Cmk1 Negative GeneticPMID:22681890
SPAC23A1.07ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
tfs1transcription elongation factor TFIIS Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
uch1ubiquitin C-terminal hydrolase Uch1 Positive GeneticPMID:22681890
spc2signal peptidase subunit Spc2 (predicted) Negative GeneticPMID:22681890
SPCC162.02cAMP-binding dehydrogenase (predicted) Negative GeneticPMID:22681890
rdp1RNA-directed RNA polymerase Rdp1 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
cut2securin, sister chromatid separation inhibitor Negative GeneticPMID:22681890
elp1elongator subunit Elp1 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
msh3MutS protein homolog 3 Negative GeneticPMID:22681890
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC70.03cproline dehydrogenase (predicted) Negative GeneticPMID:22681890
cbh2CENP-B homolog Cbh2 Positive GeneticPMID:22681890
SPAC9G1.05actin cortical patch component Aip1 (predicted) Negative GeneticPMID:22681890
nse6Smc5-6 complex non-SMC subunit Nse6 Negative GeneticPMID:22681890
SPBP16F5.05cribosome biogenesis protein Nop8 (predicted) Negative GeneticPMID:22681890
mis4adherin, cohesin loading factor Mis4 Negative GeneticPMID:23050226
hst2Sir2 family histone deacetylase Hst2 Negative GeneticPMID:18818364
SPBC21B10.03cataxin-2 homolog (predicted) Negative GeneticPMID:22681890
rpb9DNA-directed RNA polymerase II complex subunit Rpb9 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
msa1RNA-binding protein Msa1 Negative GeneticPMID:22681890
bub3mitotic spindle checkpoint protein Bub3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
arp6actin-like protein Arp6 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
rox3mediator complex subunit Med19/Rox3 Positive GeneticPMID:18818364
aps1diadenosine 5',5'''-p1,p6-hexaphosphate hydrolase Aps1 Positive GeneticPMID:22681890
dph3diphthamide biosynthesis protein Dph3 (predicted) Negative GeneticPMID:22681890
pht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
adn3transcription factor (predicted) Negative GeneticPMID:22681890
rad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
git5heterotrimeric G protein beta subunit Git5 Positive GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rpb7DNA-directed RNA polymerase complex II subunit Rpb7 Positive GeneticPMID:22681890
mad1mitotic spindle checkpoint protein Mad1 Negative GeneticPMID:18818364
cpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Negative GeneticPMID:18818364
srk1MAPK-activated protein kinase Srk1 Negative GeneticPMID:22681890
SPAC2F7.17mitochondrial peptide chain release factor (predicted) Positive GeneticPMID:22681890
laf1clr6 L associated factor 1 Laf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pds5cohesin-associated protein Pds5 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
meu27S. pombe specific UPF0300 family protein 5 Negative GeneticPMID:22681890
swi6HP1 family chromodomain protein Swi6 Positive GeneticPMID:22681890
msh6MutS protein homolog Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
spf30splicing factor Spf30 (predicted) Negative GeneticPMID:22681890
cut3condensin complex subunit Cut3 Negative GeneticPMID:22681890
cdc18MCM loader Negative GeneticPMID:22681890
mal3EB1 family Mal3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
clp1Cdc14-related protein phosphatase Clp1/Flp1 Negative GeneticPMID:22681890
mfm1M-factor precursor Mfm1 Negative GeneticPMID:22681890
alp14TOG ortholog Alp14 Negative GeneticPMID:18818364
sce3translation initiation factor (predicted) Positive GeneticPMID:22681890
SPCC4F11.03csequence orphan Positive GeneticPMID:22681890
SPAC27E2.02IMPACT homolog, translational regulator (predicted) Negative GeneticPMID:22681890
mpc2mitochondrial pyruvate transmembrane transporter subunit Mpc2 Positive GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
rok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
prp4serine/threonine protein kinase Prp4 Negative GeneticPMID:22681890
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Negative GeneticPMID:18818364
mto1MT organizer Mto1 Negative GeneticPMID:22681890
ctu2cytosolic thiouridylase subunit Ctu2 Negative GeneticPMID:22681890
SPAC6G9.14RNA-binding protein (predicted) Negative GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
apl6AP-3 adaptor complex subunit Apl6 (predicted) Negative GeneticPMID:22681890
SPBC216.01cDNA damage response protein (predicted) Negative GeneticPMID:22681890
dcc1Ctf18 RFC-like complex subunit Dcc1 Negative GeneticPMID:22681890
mph1dual specificity protein kinase Mph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
nup124nucleoporin Nup124 Negative GeneticPMID:22681890
hri2eIF2 alpha kinase Hri2 Negative GeneticPMID:22681890
apq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
lsg1Lsk1 complex gamma subunit (predicted) Negative GeneticPMID:22681890
ctp1CtIP-related endonuclease Negative GeneticPMID:22681890
SPBC1861.07elongin C (predicted) Negative GeneticPMID:22681890
pmk1MAP kinase Pmk1 Positive GeneticPMID:22681890
SPCC1840.07cphosphoprotein phosphatase (predicted) Negative GeneticPMID:22681890
nem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
SPAC926.06cleucine-rich repeat protein, unknown Negative GeneticPMID:22681890
SPBC25B2.10Usp (universal stress protein) family protein Negative GeneticPMID:22681890
arg12argininosuccinate synthase (predicted) Positive GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
alm1medial ring protein Alm1 Positive GeneticPMID:22681890
ptc3protein phosphatase 2c homolog 3 Positive GeneticPMID:18818364
ppk16serine/threonine protein kinase Ppk16 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
swr1SNF2 family helicase Swr1 Negative GeneticPMID:18818364
pop2F-box/WD repeat protein Pop2 Negative GeneticPMID:22681890
mis6inner centromere protein, CENP-I ortholog Mis6 Synthetic LethalityPMID:23267073
SPBC660.12caminotransferase (predicted) Negative GeneticPMID:22681890
get1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
rtt109RTT109 family histone lysine acetyltransferase Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Synthetic Growth DefectPMID:23050226
Negative Genetic
chp1chromodomain protein Chp1 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
hrk1haspin related kinase Hrk1 Negative GeneticPMID:22681890
mad2spindle checkpoint protein Mad2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ssr3SWI/SNF and RSC complex subunit Ssr3 Negative GeneticPMID:22681890
wis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Positive GeneticPMID:18818364
ies2Ino80 complex subunit Ies2 Negative GeneticPMID:18818364
swi3replication fork protection complex subunit Swi3 Negative GeneticPMID:18818364
mug93TPR repeat protein, meiotically spliced Negative GeneticPMID:22681890
adn2transcription factor (predicted) Negative GeneticPMID:22681890
air1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
SPAC18G6.13sequence orphan Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
ubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Positive GeneticPMID:22681890
swc5Swr1 complex subunit Swc5 Negative GeneticPMID:18818364
cwf19complexed with Cdc5 protein Cwf19 Negative GeneticPMID:22681890
msd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
vps71Swr1 complex subunit Vps71 Negative GeneticPMID:18818364
ppk32serine/threonine protein kinase Ppk32 (predicted) Negative GeneticPMID:22681890
pdp1PWWP domain protein Pdp1 Negative GeneticPMID:18818364
med20mediator complex subunit Med20 Positive GeneticPMID:18818364
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
adn1adhesion defective protein, predicted transcriptional regulator (predicted) Negative GeneticPMID:22681890
SPBC887.08sequence orphan Positive GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
tcg1single-stranded telomeric binding protein Tgc1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
ppk27serine/threonine protein kinase Ppk27 (predicted) Negative GeneticPMID:22681890
cid12poly(A) polymerase Cid12 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
hem12uroporphyrinogen decarboxylase Hem12 (predicted) Negative GeneticPMID:22681890
SPAP32A8.03cubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
abo2ATPase with bromodomain protein (predicted) Negative GeneticPMID:18818364
SPCC1322.02sequence orphan Negative GeneticPMID:22681890
gar2nucleolar protein required for rRNA processing Negative GeneticPMID:22681890
SPCC622.15csequence orphan Negative GeneticPMID:22681890
SPCC1827.04ankyrin repeat protein, unknown biological role Positive GeneticPMID:22681890
mre11Mre11 nuclease Negative GeneticPMID:18818364
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
sum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
SPAC10F6.08cHMG box protein Negative GeneticPMID:22681890
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
srb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:18818364
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
sec28coatomer epsilon subunit (predicted) Negative GeneticPMID:18818364
rho2Rho family GTPase Rho2 Positive GeneticPMID:22681890
elp4elongator complex subunit Elp4 (predicted) Negative GeneticPMID:18818364
SPAPB1E7.11csequence orphan Negative GeneticPMID:22681890
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC22A12.14cBSD domain protein, unknown biological role Negative GeneticPMID:22681890
sgf73SAGA complex subunit Sgf73 Positive GeneticPMID:22681890
otu2ubiquitin specific cysteine protease, OTU family, Otu2 Negative GeneticPMID:22681890
ubc14ubiquitin conjugating enzyme Ubc14 (predicted) Negative GeneticPMID:22681890
SPAC9.07cGTPase Rbg1 (predicted) Negative GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Negative GeneticPMID:18818364
eme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
chl1ATP-dependent DNA helicase Chl1 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rik1silencing protein Rik1 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
SPCC4B3.02cGolgi transport protein Got1 (predicted) Negative GeneticPMID:22681890
dcr1dicer Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
SPBPB2B2.09c2-dehydropantoate 2-reductase (predicted) Negative GeneticPMID:22681890
elp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
tip41TIP41-like type 2a phosphatase regulator Tip41 Negative GeneticPMID:22681890
mkh1MEK kinase (MEKK) Mkh1 Positive GeneticPMID:22681890
SPAC1A6.03cphospholipase (predicted) Negative GeneticPMID:22681890
sgo2inner centromere protein, shugoshin Sgo2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC106.13ubiquitin ligase complex subunit, involved in proteasome-dependent catabolite inactivation of FBPase (predicted) Positive GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
btf3nascent polypeptide-associated complex beta subunit Negative GeneticPMID:22681890
SPAC27D7.09cBut2 family protein Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-WesternPMID:20211136
Affinity Capture-MS
rik1silencing protein Rik1 Affinity Capture-MSPMID:21725325
Affinity Capture-MSPMID:16024659
Affinity Capture-MSPMID:17114925
cdc20DNA polymerase epsilon catalytic subunit Pol2 Affinity Capture-WesternPMID:21725325
Affinity Capture-MS
pcu4cullin 4 Affinity Capture-MSPMID:17114925
Two-hybridPMID:16157682
htb1histone H2B Htb1 Biochemical ActivityPMID:16024659
ned8ubiquitin-like protein modifier Ned8 Affinity Capture-MSPMID:17114925
mms19Dos2 silencing complex subunit Mms19 Affinity Capture-MSPMID:21725325
Affinity Capture-Western
rbx1RING-box protein 1 Affinity Capture-MSPMID:17114925
swi6HP1 family chromodomain protein Swi6 Co-localizationPMID:16040243
rad2414-3-3 protein Rad24 Affinity Capture-MSPMID:17114925
raf1Rik1-associated factor Raf1 Co-localizationPMID:16040243
Affinity Capture-WesternPMID:22319459
Affinity Capture-WesternPMID:20211136
Affinity Capture-MSPMID:17114925
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External References
Database Identifier Description
NBRP SPCC970.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCC970.07c Retrieval of eukaryotic orthologs
BioGrid SPCC970.07c BioGRID Interaction Datasets
Bähler Lab SPCC970.07c Cell Cycle Expression Profile
Bähler Lab SPCC970.07c Meiosis/Sporulation Expression Profies
Bähler Lab SPCC970.07c Pheromone response/mating expression profiles
Bähler Lab SPCC970.07c Environmental stress expression profiles
Bähler Lab SPCC970.07c Bähler Lab Transcriptome Viewer
Cyclebase SPCC970.07c Cell Cycle Data
PInt SPCC970.07c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCC970.07c Entrez Gene
SPD / RIKEN26/26F09Orfeome Localization Data
EntrezGene2539420Rik1-associated factor Raf2
Uniprot_genenameRAF2
WikiGene2539420Rik1-associated factor Raf2
UniProtKB/SwissProtO74560Rik1-associated factor 2
ModBaseO74560Database of comparative protein structure models
Pfam Protein DomainsO74560Pfam Domain Arrangement
RefSeq PeptideNP_587848Rik1-associated factor Raf2
RefSeq mRNANM_001022841972h- Rik1-associated factor Raf2 (raf2), mRNA
European Nucleotide ArchiveCAA20700ENA Protein Mapping
SPD / RIKEN26/26F09Orfeome Localization Data

Literature for raf2
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013