SPCP25A2.03

Gene Standard NameUnassigned ChromosomeIII
Systematic IDSPCP25A2.03 Gene Start1182719
Synonyms Gene End1185336
ProductTHO complex subunit (predicted) Gene Length2618
Feature Typeprotein coding CDS Start1182796
Name Description CDS End1185168
Characterisation Statusbiological_role_inferred CDS Length2373

Ensembl Gene Location
  1. SPCC4B3.02c
  2. tum1
  3. rhp26
  4. SPCP25A2.03
  5. coa4
  6. cwf5
  7. SPCC550.03c
  8. SPNCRNA.1178
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopySPCP25A2.03delta (deletion)deletionPMID:20473289
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0006368transcription elongation from RNA polymerase II promoterISSUniProtKB:Q8R3N6GO_REF:0000001
GO:0006406mRNA export from nucleusICGO:0000347GO_REF:0000001
GO Cellular Component

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0000347THO complexISSUniProtKB:Q8R3N6GO_REF:0000001
GO:0005634nucleusIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
111827191182990
211830501183940
311839961185336

References

Region Start End Reference
three_prime_UTR11851691185336PMID:21511999
five_prime_UTR11827191182795PMID:21511999
three_prime_UTR11851691185336PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF11957 IPR021861 Pfam THO complex, subunit THOC1 78 562 1
PTHR13265 hmmpanther 2 750 1
PTHR13265:SF0 hmmpanther 2 750 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517
PMID:19547744

Protein Properties

Ave. residue weight 113.35 Da
Charge -27.50
Isoelectric point 4.80
Molecular weight 85.24 kDa
Number of residues 752
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1742.34PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1752.13PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.64PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2PMID:23101633
Disease Association
DescriptionQualifierReference
cancer
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPCP25A2.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCP25A2.03 Retrieval of eukaryotic orthologs
BioGrid SPCP25A2.03 BioGRID Interaction Datasets
Bähler Lab SPCP25A2.03 Cell Cycle Expression Profile
Bähler Lab SPCP25A2.03 Meiosis/Sporulation Expression Profies
Bähler Lab SPCP25A2.03 Pheromone response/mating expression profiles
Bähler Lab SPCP25A2.03 Environmental stress expression profiles
Bähler Lab SPCP25A2.03 Bähler Lab Transcriptome Viewer
Cyclebase SPCP25A2.03 Cell Cycle Data
PInt SPCP25A2.03 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCP25A2.03 Entrez Gene
WikiGene2539396THO complex subunit (predicted)
EntrezGene2539396THO complex subunit (predicted)
SPD / RIKEN28/28E03Orfeome Localization Data
UniProtKB/SwissProtQ9URT2Uncharacterized protein P25A2.03
ModBaseQ9URT2Database of comparative protein structure models
Pfam Protein DomainsQ9URT2Pfam Domain Arrangement
RefSeq PeptideNP_588092THO complex subunit (predicted)
RefSeq mRNANM_001023083972h- THO complex subunit (predicted) (SPCP25A2.03), mRNA
European Nucleotide ArchiveCAB62828ENA Protein Mapping
UniParcUPI00000696C5UniProt Archive

Literature for SPCP25A2.03
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013