med31 (SPCP31B10.03c)

Gene Standard Namemed31 ChromosomeIII
Systematic IDSPCP31B10.03c Gene Start526837
Synonymssep10, soh1 Gene End525859
Productmediator complex subunit Med31 Gene Length979
Feature Typeprotein coding CDS Start526690
Name Description CDS End526271
Characterisation Statuspublished CDS Length420

Ensembl Gene Location
  1. prp11
  2. SPRRNA.24
  3. cwf23
  4. SPCP31B10.02
  5. med31
  6. SPCP31B10.04
  7. tdp1
  8. SPNCRNA.580
  9. mug190
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000117abnormal septationno_name (unrecorded)unrecordedPMID:10392445
FYPO:0000155flocculating cellsno_name (unrecorded)unrecordedPMID:18310102
FYPO:0000280sterilemed31delta (deletion)deletionPMID:15356001
FYPO:0002060viable vegetative cell populationMicroscopymed31delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0001104RNA polymerase II transcription cofactor activityIEAIPR008831GO_REF:0000002
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006357regulation of transcription from RNA polymerase II promoterICGO:0016592GO_REF:0000001
GO:0006366transcription from RNA polymerase II promoterIPIPMID:15356001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0016592mediator complexIGIsep11PMID:12471453
IDAPMID:15356001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1526837525859

References

Region Start End Reference
three_prime_UTR526270525859PMID:21511999
five_prime_UTR526837526691PMID:21511999
three_prime_UTR526270525859PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF05669 IPR008831 Pfam Mediator complex, subunit Med31 13 108 1
PTHR13186 IPR008831 hmmpanther Mediator complex, subunit Med31 12 139 1
PTHR13186:SF0 hmmpanther 12 139 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 121.55 Da
Charge -10.00
Isoelectric point 4.34
Molecular weight 16.90 kDa
Number of residues 139
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
deletion mutant expression profiling PMID:17922236 PMID:15829570
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.4PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.4PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
sep11mediator complex subunit Pmc6 Synthetic LethalityPMID:12471453
ste11transcription factor Ste11 Phenotypic SuppressionPMID:12471453
pmh1transcription factor TFIIH complex subunit Pmh1 Synthetic LethalityPMID:15829570
med8mediator complex subunit Med8 Synthetic LethalityPMID:17922236
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
med7mediator complex subunit Med7 Co-purificationPMID:18310102
Affinity Capture-WesternPMID:15356001
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External References
Database Identifier Description
NBRP SPCP31B10.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCP31B10.03c Retrieval of eukaryotic orthologs
BioGrid SPCP31B10.03c BioGRID Interaction Datasets
Bähler Lab SPCP31B10.03c Cell Cycle Expression Profile
Bähler Lab SPCP31B10.03c Meiosis/Sporulation Expression Profies
Bähler Lab SPCP31B10.03c Pheromone response/mating expression profiles
Bähler Lab SPCP31B10.03c Environmental stress expression profiles
Bähler Lab SPCP31B10.03c Bähler Lab Transcriptome Viewer
Cyclebase SPCP31B10.03c Cell Cycle Data
PInt SPCP31B10.03c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCP31B10.03c Entrez Gene
EntrezGene2539504mediator complex subunit Med31
Uniprot_genenameMED31
WikiGene2539504mediator complex subunit Med31
SPD / RIKEN03/03D03Orfeome Localization Data
UniProtKB/SwissProtQ9USH1Mediator of RNA polymerase II transcription subunit 31
ModBaseQ9USH1Database of comparative protein structure models
Pfam Protein DomainsQ9USH1Pfam Domain Arrangement
RefSeq PeptideNP_587859mediator complex subunit Med31
RefSeq mRNANM_001022852972h- mediator complex subunit Med31 (med31), mRNA
European Nucleotide ArchiveAAG02413ENA Protein Mapping
European Nucleotide ArchiveCAB58369ENA Protein Mapping
UniParcUPI000006BB93UniProt Archive

Literature for med31
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013