eft202 (SPCP31B10.07)

Gene Standard Nameeft202 ChromosomeIII
Systematic IDSPCP31B10.07 Gene Start537298
Synonyms Gene End539922
Producttranslation elongation factor 2 (EF-2) Eft2,B Gene Length2625
Feature Typeprotein coding CDS Start537326
Name Description CDS End539854
Characterisation Statuspublished CDS Length2529

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyeft202delta (deletion)deletionPMID:20473289
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0003746translation elongation factor activityIEAUniProtKB:KW-0251GO_REF:0000037
GO:0003924GTPase activityIEAIPR000795GO_REF:0000002
GO:0005525GTP bindingISMPFAM:PF00009GO_REF:0000001
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0005840ribosomeISOSGD:S000005659GO_REF:0000024
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1537298539922

References

Region Start End Reference
three_prime_UTR539855539922PMID:21511999
five_prime_UTR537298537325PMID:21511999
three_prime_UTR539855539922PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03144 IPR004161 Pfam Translation elongation factor EFTu/EF1A, domain 2 394 469 16
PF00009 IPR000795 Pfam Elongation factor, GTP-binding domain 18 344 18
PF03764 IPR005517 Pfam Translation elongation factor EFG/EF2, domain IV 605 720 5
PF00679 IPR000640 Pfam Translation elongation factor EFG, V domain 724 810 7
SM00889 IPR005517 SMART Translation elongation factor EFG/EF2, domain IV 604 721 4
SM00838 IPR000640 SMART Translation elongation factor EFG, V domain 723 812 7
PS00301 IPR000795 Prosite Patterns Elongation factor, GTP-binding domain 58 73 10
G3DSA:3.90.1430.10 Gene3D 229 328 4
G3DSA:3.40.50.300 Gene3D 2 228 279
G3DSA:3.30.70.240 IPR000640 Gene3D 728 828 7
G3DSA:3.30.230.10 IPR014721 Gene3D 572 727 18
G3DSA:3.30.70.870 Gene3D 486 560 7
G3DSA:2.40.30.10 Gene3D 339 484 29
SSF54211 IPR020568 SuperFamily 561 724 29
SSF54980 IPR009022 SuperFamily 484 559 7
SSF54980 IPR009022 SuperFamily 726 840 7
SSF50447 IPR009000 SuperFamily 344 481 24
SSF52540 SuperFamily 4 343 294
PR00315 IPR000795 PRINTS Elongation factor, GTP-binding domain 21 34 15
PR00315 IPR000795 PRINTS Elongation factor, GTP-binding domain 117 128 15
PR00315 IPR000795 PRINTS Elongation factor, GTP-binding domain 65 73 15
PR00315 IPR000795 PRINTS Elongation factor, GTP-binding domain 101 111 15
PR00315 IPR000795 PRINTS Elongation factor, GTP-binding domain 153 162 15
PTHR23115 hmmpanther 7 842 17
PTHR23115:SF4 hmmpanther 7 842 2
TIGR00231 IPR005225 tigrfam Small GTP-binding protein domain 20 164 35

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.73 Da
Charge -1.50
Isoelectric point 6.37
Molecular weight 93.23 kDa
Number of residues 842
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide51682.2PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide152630.81PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide63PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide7.1PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
zfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Two-hybridPMID:19682301
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
External References
Database Identifier Description
NBRP SPCP31B10.07 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPCP31B10.07 Retrieval of eukaryotic orthologs
BioGrid SPCP31B10.07 BioGRID Interaction Datasets
Bähler Lab SPCP31B10.07 Cell Cycle Expression Profile
Bähler Lab SPCP31B10.07 Meiosis/Sporulation Expression Profies
Bähler Lab SPCP31B10.07 Pheromone response/mating expression profiles
Bähler Lab SPCP31B10.07 Environmental stress expression profiles
Bähler Lab SPCP31B10.07 Bähler Lab Transcriptome Viewer
Cyclebase SPCP31B10.07 Cell Cycle Data
PInt SPCP31B10.07 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPCP31B10.07 Entrez Gene
SPD / RIKEN29/29C06Orfeome Localization Data
EntrezGene2539544translation elongation factor 2 (EF-2) Eft2,B
EntrezGene3361483translation elongation factor 2 (EF-2) Eft2,A
Uniprot_genenameEFT201
WikiGene2539544translation elongation factor 2 (EF-2) Eft2,B
WikiGene3361483translation elongation factor 2 (EF-2) Eft2,A
UniProtKB/SwissProtO14460Elongation factor 2
ModBaseO14460Database of comparative protein structure models
Pfam Protein DomainsO14460Pfam Domain Arrangement
RefSeq PeptideNP_587863translation elongation factor 2 (EF-2) Eft2,B
RefSeq mRNANM_001022856972h- translation elongation factor 2 (EF-2) Eft2,B (eft202), mRNA
European Nucleotide ArchiveBAA13813ENA Protein Mapping
European Nucleotide ArchiveBAA23590ENA Protein Mapping
European Nucleotide ArchiveBAA23591ENA Protein Mapping
European Nucleotide ArchiveCAB52147ENA Protein Mapping
European Nucleotide ArchiveCAB58373ENA Protein Mapping
UniParcUPI0000129C7EUniProt Archive

Literature for eft202

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013