srp7 (SPNCRNA.98)


Gene Standard Namesrp7 Characterisation Status
Systematic IDSPNCRNA.98 Feature TypencRNA
Synonymssrp Name Description
Product7SL signal recognition particle component Product Size499nt
Genomic Location Chromosome I, 4268566-4269064, 499nt

Ensembl Gene Location
GO Biological Process
Term NameCount
SRP-dependent cotranslational protein targeting to membrane15
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
signal recognition particle, endoplasmic reticulum targeting7
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology

Population Phenotype

Term NameAlleleExpressionCount
decreased cell population growth at high temperaturesrp7-TS-point (G107A, G112A)Not specified136
decreased cell population growth at low temperatureG159A/C164U (G159A, C164U)Not specified61
inviable vegetative cell populationA154C,G155A (A154C, G155A)Not specified1438
A154G,G155A (A154G, G155A)Not specified
D4E-1 (GC inserted after nt 158, GC inserted after nt 164)Not specified
D4E-2 (G160C, GC inserted after nt 158, GC inserted after nt 164)Not specified
G159C/C164A (G159C, C164A)Not specified
G159U/A162C (G159U, A162C)Not specified
G159U/A162U (G159U, A162U)Not specified
PTL1-2 (GAAA160CUUC)Not specified
PTL2C (GAAAC160CUUCA)Not specified
PTL2U (GAAAC160UUUCA)Not specified
srp7-A-159,A-160 (G159A, G160A)Not specified
srp7-C-159 (G159C)Not specified
srp7-C-160 (G160C)Not specified
srp7-T-160 (G160T)Not specified
srp7-TS-point (G107A, G112A)Not specified
srp7::ura4+ (disruption)Null
srp7Δ-domIII (70-87, 137-204)Not specified
STL1-1 (GAAAC160UUCGG)Not specified
STL1-2 (GGAAA159CUUCG)Not specified
U158C/A166C (U158C, A166C)Not specified
unnamed (118-120)Not specified
unnamed (139-144)Not specified
unnamed (159-161)Not specified
unnamed (A146U, G159U, nt148-150 deletion)Not specified
unnamed (G153A, G155A)Not specified
unnamed (G155A, G156A, G160A)Not specified
unnamed (G160A, C164A)Not specified
unnamed (G72A, G78A, G100A, G107A, Gl12A, G141A)Not specified
unnamed (U88G, nt84 deletion, 8 nucleotides inserted after nt83)Not specified
unnamed (U88G, nt84-88 deletion, 131 nucleotides inserted after nt83)Not specified
sensitive to high osmolarityA154U (A154U)Not specified11
A162 (A162)Not specified
A162C/C164G (A162C, C164G)Not specified
A166C (A166C)Not specified
C164A (C164A)Not specified
G155A (G155A)Not specified
G159A (G159A)Not specified
G159C/C164G (G159C, C164G)Not specified
G159U (G159U)Not specified
G159U/C164A (G159U, C164A)Not specified
PTL1-1 (GAAA160UUUC)Not specified
srp7-A-159,C-161 (G159A, A161C)Not specified
srp7-A-160 (G160A)Not specified
srp7-A154U (A154U)Not specified
srp7-C-162,C-163 (A162C, A163C)Not specified
srp7-C-163 (A163C)Not specified
srp7-C-163,A-164 (A163C, G164A)Not specified
srp7-G-163 (A163G)Not specified
srp7-G-164 (C164G)Not specified
srp7-G4C (G4C)Not specified
srp7-T-159,T-164 (G159T, C164T)Not specified
srp7-T-163 (A163T)Not specified
srp7-T-164 (C164T)Not specified
STL1-3 (GAAA160UUCG)Not specified
STL2-1 (GGAAAC159CUUCGG)Not specified
U157G/A165G (U157G, A165G)Not specified
unnamed (C180U, U inserted after nt 176)Not specified
slow vegetative cell population growthsrp7-A-159,C-161 (G159A, A161C)Not specified328
viable vegetative cell populationA162C (A162C)Not specified3809
A162C/C164G (A162C, C164G)Not specified
A165G (A165G)Not specified
A166C (A166C)Not specified
BP-Comp (U157G, U158C, A165G, A166C)Not specified
C164A (C164A)Not specified
D4E-3 (GC inserted after nt 164)Not specified
G159A (G159A)Not specified
G159A/C164U (G159A, C164U)Not specified
G159U (G159U)Not specified
G159U/C164A (G159U, C164A)Not specified
PTL1-1 (GAAA160UUUC)Not specified
srp7-A-160 (G160A)Not specified
srp7-A154U (A154U)Not specified
srp7-C-161 (A161C)Not specified
srp7-C-162,C-163 (A162C, A163C)Not specified
srp7-C-163 (A163C)Not specified
srp7-C-163,A-164 (A163C, G164A)Not specified
srp7-G-161 (A161G)Not specified
srp7-G-163 (A163G)Not specified
srp7-G-164 (C164G)Not specified
srp7-G4C (G4C)Not specified
srp7-T-159,T-164 (G159T, C164T)Not specified
srp7-T-163 (A163T)Not specified
srp7-T-164 (C164T)Not specified
srp7-TS-point (G107A, G112A)Not specified
STL2-1 (GGAAAC159CUUCGG)Not specified
U157G (U157G)Not specified
U157G/A165G (U157G, A165G)Not specified
U157G/U158C (U157G, U158C)Not specified
U158C (U158C)Not specified
unnamed (A149)Not specified
unnamed (A163U, C169U6)Not specified
unnamed (A170C)Not specified
unnamed (A172U)Not specified
unnamed (A175G)Not specified
unnamed (A192C, G193C)Not specified
unnamed (C138G, A150G)Not specified
unnamed (C174G)Not specified
unnamed (C179U, C180U)Not specified
unnamed (C180A)Not specified
unnamed (C180A, G181A)Not specified
unnamed (C180G)Not specified
unnamed (C180U)Not specified
unnamed (C180U, U inserted after nt 176)Not specified
unnamed (C69A, G127A)Not specified
unnamed (C69A, U70C)Not specified
unnamed (C69U)Not specified
unnamed (C69U, U70C)Not specified
unnamed (C77A)Not specified
unnamed (G100A, C103A, G112A)Not specified
unnamed (G104A)Not specified
unnamed (G118A)Not specified
unnamed (G121C)Not specified
unnamed (G139A, G141A)Not specified
unnamed (G139C, G144C, A162C)Not specified
unnamed (G141A, C148A)Not specified
unnamed (G144C)Not specified
unnamed (G144C, G149C)Not specified
unnamed (G149A)Not specified
unnamed (G149A, G152A)Not specified
unnamed (G156A, G159A)Not specified
unnamed (G15A)Not specified
unnamed (G181C)Not specified
unnamed (G182A)Not specified
unnamed (G226C)Not specified
unnamed (G4A)Not specified
unnamed (G4A, G9A)Not specified
unnamed (G4C)Not specified
unnamed (G60A, G61A)Not specified
unnamed (G72A, G78A, G100A, G107A, Gl12A, G141A)Not specified
unnamed (G78A)Not specified
unnamed (G9A)Not specified
unnamed (T(-5)C, T(-3)C, U88C)Not specified
unnamed (T(-61)C, G(-75)C, U62C, U101C)Not specified
unnamed (U101C)Not specified
unnamed (U101C, A136C, G149C)Not specified
unnamed (U101C, U140C)Not specified
unnamed (U119C, U126C)Not specified
unnamed (U12A, U13A, U47A)Not specified
unnamed (U133C, A135C)Not specified
unnamed (U142C)Not specified
unnamed (U167G)Not specified
unnamed (U173C)Not specified
unnamed (U24C, U45C, U62C, U119C, G144C)Not specified
unnamed (U57C, U62C, U90C)Not specified
unnamed (U70C)Not specified
unnamed (U88G)Not specified
unnamed (U88G, nt84-88 deletion, 131 nucleotides inserted after nt83)Not specified
unnamed (U88G, U133C, A135C)Not specified
unnamed (U88G, UCGA inserted after nt84)Not specified

Cell Phenotype

Term NameAlleleExpressionCount
abolished RNA binding10
affecting srp7srp7-A154U (A154U)Not specified
affecting srp7srp7-G4C (G4C)Not specified
affecting srp7srp7-TS-point (G107A, G112A)Not specified
decreased protein binding66
affecting srp54 and srp7A154U (A154U)Not specified
affecting srp54 and srp7A166C (A166C)Not specified
affecting srp54 and srp7G155A (G155A)Not specified
affecting srp54 and srp7G156A (G156A)Not specified
affecting srp54 and srp7G159A (G159A)Not specified
affecting srp54 and srp7srp7-A-159,A-160 (G159A, G160A)Not specified
affecting srp54 and srp7STL1-3 (GAAA160UUCG)Not specified
affecting srp54 and srp7unnamed (U158C, A166C)Not specified
increased RNA level during vegetative growth200
affecting srp7srp7-A-159,A-160 (G159A, G160A)Not specified
affecting srp7srp7-C-159 (G159C)Not specified
affecting srp7srp7-C-160 (G160C)Not specified
affecting srp7srp7-T-160 (G160T)Not specified
inviable after spore germination, single or double cell divisionsrp7::ura4+ (disruption)Null103
inviable sporesrp7.1 (disruption (srp7::m-Tn3(Leu2)))Null472
normal protein binding56
affecting srp54 and srp7A161C (A161C)Not specified
affecting srp54 and srp7G159C,C164G (G159C, C164G)Not specified
affecting srp54 and srp7G160A (G160A)Not specified
affecting srp54 and srp7STL2-1 (GGAAAC159CUUCGG)Not specified
affecting srp54 and srp7U157G,A165G (U157G, A165G)Not specified
Target Of
OntologyRelationshipGeneProduct
FYPO affected by mutation in smn1 SMN family protein Smn1
FYPO affected by mutation in srp7 7SL signal recognition particle component
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4268566..4269064
CDS4268662..4268916PMID:16453822
CDS4268662..4268916PMID:2837764
CDS4268662..4268916X15220
Sequence
Gene Expression

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1300during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
280during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bysmn1SMN family protein Smn1 Affinity Capture-RNAPMID:23221635
co-purifies withsrp54signal recognition particle subunit Srp54 Co-purificationPMID:8041618
External References
Database Identifier Description
NBRP SPNCRNA.98 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPNCRNA.98 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPNCRNA.98 BioGRID Interaction Datasets
Expression Viewer SPNCRNA.98 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPNCRNA.98 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPNCRNA.98 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPNCRNA.98 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPNCRNA.98 Polyadenylation Viewer (Gullerova lab)
pombeTV SPNCRNA.98 Transcriptome Viewer (Bähler Lab)
GEO SPNCRNA.98 GEO profiles
PInt SPNCRNA.98 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPNCRNA.98 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPNCRNA.98 Fission yeast phenotypic data & analysis
Cyclebase SPNCRNA.98.1 Cell Cycle Data
RfamRF00017Rfam hosted at the Wellcome Trust Sanger Institute

Literature for srp7

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015