Centromeres

At present, each centromere is annotated as a single sequence feature in PomBase, which can be viewed in and downloaded from the Ensembl genome browser.

Chromosome coordinates (links to Ensembl genome browser):

• CEN 1:  I:3753687-3789421
• CEN 2: II:1602264-1644747
• CEN 3: III:1070904-1137003

The 3 centromeres are also available as contiguated sequence (the remaining gaps in CEN2 and CEN3 are represented by 100 N's)

• CEN 1 (gzipped EMBL format)
• CEN 2 (gzipped EMBL format)
• CEN 3 (gzipped EMBL format)

Note that specific repeats within centromeres are not yet annotated in PomBase, but are shown in the diagram below. To see the repeat sequences, download and unzip the contiguated sequence files and view them in Artemis.

Note: Recent work by Chad Ellermeier and Gerry Smith suggests that there are only 4 +/- 1 copies of the 6760 bp repeat missing from chromosome 3

Please note: This is a schematic diagram. Distances and overlaps are approximate. Please refer to the sequence data to design experimental constructs.

Centromere Map from: The genome sequence of Schizosaccharomyces pombe.
Nature 2002 Feb 21;415(6874):871-80. created by Rhian Gwilliam