The difference is in the details: Structural and mechanistic variations in the LAMTOR-Gtr/Rag module.
In this issue of Structure, Tettoni et al. present the structure and biochemical characterization of the fission yeast LAMTOR-Gtr complex, which mediates nutrient-dependent control of cell growth. The study reveals specific differences to the homologous human LAMTOR-Rag complex that might represent means of evolutionary adaptation.
Titze S, Kümmel D