intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
GO:0034976
response to endoplasmic reticulum stress
is_a
GO:0097193
intrinsic apoptotic signaling pathway
is_a
ER stress-induced apoptosis
exact
apoptosis in response to ER stress
exact
apoptosis in response to endoplasmic reticulum stress
broad
apoptosis triggered by ER stress
exact
endoplasmic reticulum stress-induced apoptosis
exact
intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress
exact