SAGA complex
A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
GO:0070461
SAGA-type complex
is_a
GO:1905368
peptidase complex
is_a
PCAF complex
narrow
PCAF histone acetylase-associated complex
narrow
SPT3-TAF9-GCN5 acetylase complex
related
SPT3-TAF9-PCAF acetylase complex
narrow
STAGA coactivator complex
related
STAGA complex
related
Spt-Ada-Gcn5-acetyltransferase complex
exact
SPBC1921.07c SPCC61.02 SPCC16C4.18c SPAC1952.05 SPBC6B1.12c SPBC25H2.11c SPAC15A10.02 SPCC24B10.08c SPBC28F2.10c SPCC5E4.03c SPCC126.04c SPAC57A10.14 SPAC13A11.04c SPBC887.18c SPAC12G12.05c SPBP16F5.03c SPBC14C8.17c SPAC4D7.10c SPBC21H7.02