choriocarcinoma
An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.
MONDO:0002178
placenta cancer
excluded_subClassOf
MONDO:0004970
adenocarcinoma
excluded_subClassOf
MONDO:0002872
trophoblastic neoplasm
is_a
MONDO:0005040
germ cell tumor
is_a
chorioblastoma
exact
choriocarcinoma
exact
choriocarcinoma (disease)
exact
choriocarcinoma, malignant
exact
chorioepithelioma
exact
chorion carcinoma
exact
chorionic carcinoma
exact