Mitochondrial porin and phospholipid scramblase; voltage-dependent anion channel in the outer mitochondrial membrane required for maintenance of mitochondrial osmotic stability and membrane permeability; scramblase involved in mitochondrial transbilayer phospholipid translocation; regulates TOM complex assembly; role in mitochondrial import of carrier precursors and metabolites; binds ubiquinone; protein abundance increases in response to DNA replication stress; orthologous to human VDAC1/2