phosphorelay sensor kinase activity
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
GO:0004673
protein histidine kinase activity
is_a
GO:0140299
molecular sensor activity
is_a
two-component sensor activity
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two-component sensor molecule
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two-component system sensor activity
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SPAC27E2.09 SPCC74.06 SPAC1834.08