G-quadruplex DNA binding
Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
GO:0003677
DNA binding
is_a
G quadruplex DNA binding
exact
G quartet DNA binding
exact
G quartet binding
broad
G-DNA binding
exact
G-quartet DNA binding
exact
G-quartet binding
broad
quadruplex DNA binding
exact
tetraplex DNA binding
exact
SPAC1556.01c SPAC6F6.17 SPBC887.14c