CLOCK-BMAL transcription complex
Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.
GO:0090575
RNA polymerase II transcription regulator complex
is_a
CLOCK/BMAL complex
exact