execution phase of necroptosis
A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.
GO:0009987
cellular process
is_a
GO:0070266
necroptotic process
part_of
execution phase of necroptotic process
exact
necroptosis
broad
necroptotic execution phase
exact