hereditary spastic paraplegia
Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia of the lower limbs.
MONDO:0003757
paraplegia
is_a
MONDO:0024237
inherited neurodegenerative disorder
is_a
MONDO:0100546
hereditary neuromuscular disease
is_a
FSP
related
HSP
exact
SPG
exact
Strümpell-Lorrain disease
exact
familial spastic paraparesis
related
familial spastic paraplegia
exact
hereditary spastic paraparesis
exact
spastic paraplegia
broad
SPBC21B10.09 SPAC19G12.08 SPAC15E1.05c SPBC30D10.09c SPAC23A1.07 SPBC31A8.01c SPAC12G12.04 SPAC21E11.07 SPAC1420.02c SPAC20G8.02 SPCC1020.13c SPCC4B3.04c SPBC577.06c SPAC328.04 SPAC4F8.15 SPBC1105.18c SPAC821.11 SPBC947.01 SPCC1672.11c SPAC17H9.13c SPBC354.08c SPAC29A4.19c SPAC3A11.04 SPAC2G11.09 SPBC1709.19c SPAC144.14 SPCC736.03c SPAC24H6.13 SPBC17A3.04c SPBC106.04 SPAC23A1.05 SPBC582.08