PCNA complex
A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation.
GO:0044796
DNA polymerase processivity factor complex
is_a
GO:0140513
nuclear protein-containing complex
is_a
PCNA homotrimer
exact
proliferating cell nuclear antigen complex
exact
sliding clamp
broad
SPBC16D10.09