abnormal spatio-temporal regulation of replication fork localization
A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the spatio-temporal pattern of localization of replication forks into nuclear foci is abnormal. Normally, replication forks appear organized into foci outside the nucleolus in early S phase. As S phase progresses, the number of foci first increases, then decreases, and the remaining foci concentrate within the nucleolus or at the nucleolar periphery. The last replication foci remaining at the end of S phase are one or two large spots at the nucleolar border.
FYPO:0001362
abnormal cellular process during vegetative growth
is_a
abnormal replication foci dynamics
related
abnormal replication focus organization
related
abnormal spatio-temporal regulation of replication fork localisation
exact
abnormal spatio-temporal regulation of replication fork localization during mitotic cell cycle
related
abnormal spatio-temporal regulation of replication fork localization during vegetative growth
exact
abnormal spatio-temporal replication fork organization
related