tRNA (cytidine(4)/adenine(4)-2'-O-ribose)-methyltransferase activity
Catalysis of the reaction: cytidine(4) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA + S-adenosyl-L-homocysteine + H+. Acts on  cytidine(4) on tRNAPro and tRNAGly(GCC), and on adenosine(4) in tRNAHis.
GO:0016426
tRNA (adenine) methyltransferase activity
is_a
GO:0016427
tRNA (cytidine) methyltransferase activity
is_a
SPAC1805.03c