obsolete G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate (obsolete GO:0086033)
OBSOLETE. A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate.
G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate
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M2 receptor signalling pathway involved in negative regulation of heart rate
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muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate
exact
muscarinic receptor signalling pathway involved in negative regulation of heart rate
exact