MAP kinase activity
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
GO:0004674
protein serine/threonine kinase activity
is_a
ATP:protein phosphotransferase (MAPKK-activated) activity
related
ERK
related
ERK1
exact
ERK2
related
MAP kinase 1 activity
narrow
MAP kinase 2 activity
narrow
MAPK
related
MBP kinase I activity
narrow
MBP kinase II activity
narrow
SAP kinase activity
narrow
SAPK
narrow
extracellular signal-regulated kinase activity
narrow
mitogen activated kinase activity
exact
mitogen-activated protein kinase activity
related
myelin basic protein kinase activity
narrow
stress-activated kinase activity
narrow
stress-activated protein kinase activity
narrow
SPAC24B11.06c SPBC119.08 SPAC31G5.09c