phosphatidylinositol-4,5-bisphosphate phospholipase C activity
Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H+.
GO:0004629
C-type glycerophospholipase activity
is_a
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
related
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
related
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity
exact
PI-PLC activity
related
monophosphatidylinositol phosphodiesterase activity
broad
phosphatidylinositol phospholipase C activity
broad
phosphatidylinositol-4,5-bisphosphate hydrolysis
related
phosphatidylinositol-4,5-bisphosphate phospholipase C-type activity
exact
phosphoinositidase C activity
related
phosphoinositide phospholipase C activity
related
triphosphoinositide phosphodiesterase activity
broad
SPAC22F8.11