NMD_triggering_variant
A sequence variant that leads to a change in the location of a termination codon in a transcript that leads to nonsense-mediated decay (NMD). The change in location of a termination codon can be caused by several different types of sequence variants, including stop_gained (SO:0001587), frameshift_variant (SO:0001589), splice_donor_variant (SO:0001575), and splice_acceptor_variant (SO:0001574) types of variants.
SO:0002218
functionally_abnormal
is_a
NMD triggering variant
exact
nonsense-mediated decay triggering variant
exact