hyper-IgM syndrome type 3
A form of Hyper IgM syndrome characterized by mutations of the CD40 gene. In this type, Immature B cells cannot receive signal 2 from helper T cells which is necessary to mature into mature B cells.
MONDO:0003947
hyper-IgM syndrome
is_a
CD40 hyper-IgM syndrome
exact
HIGM3
exact
hyper IgM syndrome 3
related
hyper-IgM syndrome caused by mutation in CD40
exact
hyper-IgM syndrome due to CD40 deficiency
exact
immunodeficiency with hyper IgM type 3
related
immunodeficiency with hyper-IgM type 3
exact
immunodeficiency with hyper-IgM, type 3
related