chilblain lupus
A rare, chronic cutaneous lupus erythematosus disease characterized by red or violaceous, initially pruritic (evolving to painful) papules and plaques located on acral areas (especially dorsal aspects of fingers and toes, while the nose and ear involvement is uncommon), exacerbated by cold and damp conditions, with fissuring and ulceration occasionally observed. Coexistence of discoid lupus erythematosus lesions elsewhere on the body and occasional progression to systemic lupus erythematosus may be associated. Histological examination and direct immunofluorescence studies reveal nonspecific inflammatory lupus erythematosus changes while results of cryoglobulin and cold agglutinin studies are negative.
MONDO:0015948
obsolete rare genetic skin vascular disorder (obsolete MONDO:0015948)
excluded_subClassOf
MONDO:0000603
autoimmune disorder of cardiovascular system
is_a
MONDO:0015574
chronic cutaneous lupus erythematosus
is_a
MONDO:0019293
skin vascular disease
is_a
CHLE
exact
Hutchinson lupus
exact