mitochondrial permeability transition pore complex
A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).
GO:0046930
pore complex
is_a
GO:0098798
mitochondrial protein-containing complex
is_a
GO:0005740
mitochondrial envelope
part_of
MPTP complex
exact
PTPC
broad
mitochondrial PT pore complex
exact
SPBC530.10c