symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity
A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
GO:0039537
symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway
is_a
inhibition of host IRF7 by virus
related
inhibition of host interferon regulatory factor-7 by virus
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suppression by virus of host IRF7 activity
related
suppression by virus of host interferon regulatory factor 7 activity
related
suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity
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