systemic sclerosis
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension.
MONDO:0005087
respiratory system disorder
excluded_subClassOf
MONDO:0016345
non-familial restrictive cardiomyopathy
excluded_subClassOf
MONDO:0019724
obsolete secondary glomerular disease (obsolete MONDO:0019724)
excluded_subClassOf
MONDO:0005093
skin disorder
is_a
MONDO:0019340
scleroderma
is_a
SSc
exact
SSc, diffuse sclerosis
narrow
Scleroderma
broad
Scleroderma, diffuse
narrow
Scleroderma, systemic
exact
Systemic Scleroderma
exact
diffuse Scleroderma
narrow
diffuse sclerosis
narrow
systemic Scleroderma
exact
systemic scleroderma
exact
systemic sclerosis
exact