DSIF complex
A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.
GO:0008023
transcription elongation factor complex
is_a
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex
exact
DRB sensitivity inducing factor complex
exact
Spt4-Spt5 complex
exact
Spt5-Spt4 complex
exact
SPBC21C3.16c SPAC23C4.19