Bridge-like lipid transfer protein; role in vacuolar protein sorting, protein retention in the Golgi, and prospore membrane formation; required for mitochondrial integrity and ER packaging into autophagosomes during cortical reticulophagy; role in membrane remodeling for MVB biogenesis; involved in NVJ integrity and nucleophagy; localizes to the prospore membrane and membrane contact sites; human VPS13A and VPS13B homolog, involved in Chorea-acanthocytosis and Cohen syndrome, respectively