Wolfram syndrome
Wolfram syndrome (WS) also known as DIDMOAD, is a neurodegenerative disorder characterized by type I diabetes mellitus (DM), diabetes insipidus (DI), sensorineural deafness (D), bilateral optical atrophy (OA) and neurological signs. Other related problems are urinary tract atony, ataxia, peripheral neuropathy, psychiatric disorders and/or seizures. 2 types of WS may be distinguished: type 1 and type 2 (WS1 and WS2).
MONDO:0002254
syndromic disease
is_a
DIDMOAD
exact
DIDMOAD syndrome
exact
Wolfram syndrome
exact
diabetes insipidus, diabetes mellitus, optic atrophy, and deafness syndrome
exact
diabetes insipidus-diabetes mellitus-optic atrophy-deafness syndrome
exact
diabetes mellitus and insipidus with optic atrophy and deafness
exact