gene silencing by piRNA-directed DNA methylation
A small RNA-based gene silencing process in which Piwi-associated RNAs (piRNAs) guide de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.
GO:0006346
DNA methylation-dependent constitutive heterochromatin formation
is_a
GO:0140966
piRNA-mediated heterochromatin formation
is_a