guanyl-nucleotide exchange factor activity
Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.
GO:0030695
GTPase regulator activity
is_a
ARF guanyl-nucleotide exchange factor activity
narrow
GDP-dissociation stimulator activity
exact
GDS
exact
GEF
exact
GNRP
narrow
Rab guanyl-nucleotide exchange factor activity
narrow
Rac guanyl-nucleotide exchange factor activity
narrow
Ral guanyl-nucleotide exchange factor activity
narrow
Ran guanyl-nucleotide exchange factor activity
narrow
Rap guanyl-nucleotide exchange factor activity
narrow
Ras guanyl-nucleotide exchange factor activity
narrow
Rho guanine nucleotide exchange factor
exact
Rho guanyl-nucleotide exchange factor activity
narrow
RhoGEF
exact
Sar guanyl-nucleotide exchange factor activity
narrow
cAMP-dependent guanyl-nucleotide exchange factor activity
narrow
guanyl-nucleotide release factor activity
exact
guanyl-nucleotide releasing factor
exact
SPAC1006.06 SPBC2G2.03c SPCC645.07 SPBC1778.05c SPBC23E6.08 SPBC336.03 SPAC31A2.16 SPBC3H7.01 SPAC11H11.04 SPAC11E3.11c SPAC4A8.15c SPBC29A10.11c SPCC1442.01 SPAC21E11.06 SPAC57A10.04 SPAC26F1.01 SPBC800.07c SPAC1805.10 SPAC30.01c SPBC29A3.17 SPAC1D4.03c SPAC644.18c SPAC3F10.10c SPBC3E7.04c SPAC4D7.01c SPCC297.05 SPCC1450.04 SPBC211.03c SPAC23D3.13c SPBC4C3.04c SPAC23H4.14 SPAC1851.04c SPAC343.14c SPAC24H6.09 SPAC6G9.04 SPCC1183.12 SPAC19A8.01c SPAC23C4.10 SPAC4F8.03 SPCC1753.02c SPCC1494.03 SPCC1840.01c SPCC11E10.07c SPAC3G9.16c SPAC8C9.15c SPBC557.03c SPAC16E8.09 SPBC4F6.10 SPAC4D7.09 SPCC645.06c SPCC285.14