methyltransferase cap2 activity
Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the second transcribed nucleotide of mRNAs and snRNAs.
GO:0008171
O-methyltransferase activity
is_a
GO:0008173
RNA methyltransferase activity
is_a
cap2-MTase activity
exact
mRNA (nucleoside-2'-O-)-methyltransferase activity
related