transcription coactivator activity
A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.
GO:0003712
transcription coregulator activity
is_a
RNA polymerase II transcription co-activator activity
related
RNA polymerase II transcription coactivator activity
related
RNA polymerase II transcription mediator activity
related
transcription co-activator activity
exact
SPCP31B10.03c SPAC12G12.05c SPAC22H10.11c SPAC644.10 SPBC6B1.12c SPBC2D10.06 SPAC2F7.04 SPAC17G8.05 SPBC23G7.09 SPBC887.18c SPBC1604.10 SPAC13A11.04c SPBC2F12.11c SPCC126.04c SPAC14C4.12c SPBC21.04 SPCC24B10.08c SPBC1921.07c SPAC30D11.08c SPBC21B10.13c SPBC83.17 SPCC5E4.03c SPBC28F2.10c SPBC1A4.10c SPAC8C9.11 SPAC1952.05 SPBC14C8.17c SPAC1002.15c SPAC26H5.05 SPCC61.02 SPAC589.02c SPAC23E2.02 SPAC16A10.02 SPBC31F10.04c SPAC688.08 SPAC15A10.02 SPBC26H8.06 SPAC24C9.04 SPAC4D7.10c SPBC21H7.02 SPCC16C4.18c SPCC1450.05c SPBC25H2.11c SPAC17C9.05c SPBC1105.06 SPBC31F10.09c SPBC29A10.12 SPBC146.01 SPAC29A4.07 SPAC5D6.05 SPCC1682.13 SPAC29B12.11c SPBC12D12.06 SPAC57A10.14 SPBP16F5.03c SPBC14F5.08 SPAC23H4.17c