Lynch syndrome 5
An autosomal dominant hereditary neoplastic syndrome caused by pathogenic variants in the MSH6 mismatch repair gene. It is characterized by an increased risk of colorectal cancer in the absence of extensive polyposis, endometrial, ovarian, gastric, small intestinal, and urinary tract cancers, often occuring at younger ages.
MONDO:0005835
Lynch syndrome
is_a
HNPCC5
related
MSH6 hereditary nonpolyposis colon cancer
exact
MSH6-related Lynch Syndrome
exact
colorectal cancer, hereditary nonpolyposis, type 5
exact
hereditary nonpolyposis colon cancer caused by mutation in MSH6
exact
SPCC285.16c