alkylbase DNA N-glycosylase activity
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
GO:0019104
DNA N-glycosylase activity
is_a
3-methyladenine DNA glycosylase II
related
AlkA
related
DNA glycosidase II activity
related
DNA-3-methyladenine glycosidase II activity
exact
DNA-3-methyladenine glycosylase II
related
alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
broad
alkylbase DNA glycosidase activity
exact
deoxyribonucleate 3-methyladenine glycosidase II
related
SPAPB24D3.04c