extrinsic apoptotic signaling pathway
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
GO:0007166
cell surface receptor signaling pathway
is_a
GO:0097190
apoptotic signaling pathway
is_a
death receptor-mediated apoptosis
narrow
extrinsic apoptosis
narrow
extrinsic apoptotic pathway
exact
extrinsic apoptotic signaling pathway in presence of ligand
narrow
extrinsic apoptotic signalling pathway
exact