mitotic spindle assembly checkpoint signaling
A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC).
GO:0045841
negative regulation of mitotic metaphase/anaphase transition
is_a
GO:0071173
spindle assembly checkpoint signaling
is_a
GO:0071174
mitotic spindle checkpoint signaling
is_a
Dma1-dependent checkpoint
narrow
Mad2-dependent checkpoint
narrow
SAC-independent checkpoint
narrow
mitotic cell cycle spindle assembly checkpoint
exact
mitotic checkpoint
exact
mitotic spindle assembly checkpoint
exact
mitotic spindle assembly checkpoint signalling
exact
signal transduction involved in Dma1-dependent checkpoint
narrow
signal transduction involved in SAC-independent checkpoint
narrow
signal transduction involved in mitotic cell cycle spindle assembly checkpoint
exact
signal transduction involved in mitotic spindle assembly checkpoint
exact
signaling cascade involved in Dma1-dependent checkpoint
narrow
signaling cascade involved in SAC-independent checkpoint
narrow
signaling pathway involved in Dma1-dependent checkpoint
related
signaling pathway involved in SAC-independent checkpoint
related
signalling cascade involved in Dma1-dependent checkpoint
narrow
signalling cascade involved in SAC-independent checkpoint
narrow
signalling pathway involved in Dma1-dependent checkpoint
related
signalling pathway involved in SAC-independent checkpoint
related
SPBC20F10.06 SPBC106.01 SPAC23C4.12 SPCC1795.01c SPBC2F12.13 SPBC582.03 SPCC1322.12c SPAC17G8.10c SPBC776.02c SPBC25D12.02c SPBC1685.15c SPCC1020.02 SPAC23H3.08c SPCC320.13c SPBC3D6.04c SPAC6B12.13 SPCC188.02 SPCC1259.15c SPAC6F12.12