general transcription initiation factor activity
A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact subunit composition at individual promoters may vary.
GO:0003674
molecular_function
is_a
GTF activity
exact
basal transcription factor activity
exact
general transcription factor activity
exact
SPBC21H7.02 SPAC1002.04c SPBC21H7.05 SPBC30B4.07c SPBC31F10.04c SPBC30D10.02 SPBC336.09c SPBC725.17c SPCC1682.07 SPBC28F2.09 SPCC285.17 SPCC1672.08c SPBP16F5.02 SPAC29E6.08 SPCC1259.06 SPBC776.18c SPAC22E12.08 SPBC1826.01c SPBC1198.13c SPCC553.11c SPCC16C4.18c SPAC17A5.06 SPBC336.07 SPCC1919.14c SPAC18G6.11c SPCC1494.02c SPBC19F8.07 SPCC16C4.14c SPBC13E7.10c SPCC5E4.03c SPAC13A11.04c SPAC23G3.09 SPAC1250.07 SPAC15A10.02 SPCC1620.09c SPAC29A4.10 SPAC16E8.11c SPBC3B8.11 SPBC32F12.15 SPAC823.06 SPAC2G11.14 SPBC28F2.11 SPAC13F5.02c SPAC6F12.11c SPAC17G8.03c SPAC458.07 SPBC13G1.13 SPAC16E8.16 SPAC12G12.05c SPAC144.09c SPBC8D2.07c SPAC3A12.05c SPAC1D4.12 SPBC17D1.04 SPBC15D4.14 SPAC22H12.02