autoimmune encephalopathy with parasomnia and obstructive sleep apnea
Autoimmune encephalopathy with parasomnia and obstructive sleep apnea is a rare neurologic disorder characterized by a unique non-REM and REM parasomnia with sleep breathing dysfunction, gait instability and repetitive episodes of respiratory insufficiency, as well as autoantibodies against IgLON5. Patients may present stridor, chorea, limb ataxia, abnormal ocular movements, and bulbar symptoms (i.e. dysphagia, dysarthria, episodic central hypoventilation) with normal brain MRI. Excessive day sleepiness and cognitive deterioration have also been reported.
MONDO:0000568
autoimmune disorder of central nervous system
is_a
MONDO:0003406
sleep-wake disorder
is_a
MONDO:0005560
brain disorder
is_a
anti-IgLON5 disease
exact
anti-IgLON5 syndrome
exact