acute myeloid leukemia, FLT3 internal tandem duplication
Any acute myeloid leukemia that has the chromosomal anomaly FLT3 internal tandem duplication. (A genetic abnormality that arises from duplications of the juxtamembrane portion of the gene and results in constitutive activation of the FLT3 receptor tyrosine kinase protein in early hematopoietic progenitor cells. It is associated with acute myelogenous leukemia where it appears to correlate with a poor prognosis.)
MONDO:0018874
acute myeloid leukemia
is_a
AML, Activating FLT3-ITD Gene Mutation
exact
AML, Activating FLT3-ITD Mutation
exact
AML, FLT3 ITD
exact
AML, FLT3 internal tandem duplication
exact
AML, FLT3-ITD
exact
AML, FLT3-ITD Activating Mutation
exact
AML, FLT3-ITD Mutation
exact
AML, FLT3/ITD Mutation
exact