von Willebrand disease type 2B
A subtype of type 2 VWD characterized by a bleeding disorder associated with an increase in the affinity of the Willebrand factor (von Willebrand factor; VWF) for platelets. This anomaly results in spontaneous binding of high molecular weight VWF multimers to platelets leading to rapid clearance of both the platelets (increasing the risk of thrombocytopenia) and the high molecular weight VWF multimers from the plasma.
MONDO:0013304
von Willebrand disease 2
is_a
von Willebrand disease type 2B
exact
von Willebrand disease, type 2B
exact