siRNA-mediated gene silencing by mRNA destabilization
An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
GO:0061157
mRNA destabilization
is_a
GO:0140766
siRNA-mediated post-transcriptional gene silencing
is_a
gene silencing by mRNA cleavage
broad
mRNA cleavage involved in gene silencing by siRNA
exact
mRNA destabilization-mediated gene silencing by siRNA
exact