MDA-5 signaling pathway
The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.
GO:0002753
cytoplasmic pattern recognition receptor signaling pathway
is_a
IFIH1 signaling pathway
exact
MDA-5 signalling pathway
exact
MDA5 signaling pathway
narrow
melanoma differentiation-associated gene 5 signaling pathway
exact