craniosynostosis 7
Craniosynostosis is a primary abnormality of skull growth involving premature fusion of the cranial sutures such that the growth velocity of the skull often cannot match that of the developing brain. This produces skull deformity and, in some cases, raises intracranial pressure, which must be treated promptly to avoid permanent neurodevelopmental disability (summary by {1:Fitzpatrick, 2013}).nnFor a discussion of genetic heterogeneity of craniosynostosis, see CRS1 (OMIM:123100).
MONDO:0015469
craniosynostosis
excluded_subClassOf
MONDO:0020573
inherited disease susceptibility
is_a
MONDO:0700324
SMAD6-related disease
is_a
CRS7
related
craniosynostosis 7
exact
craniosynostosis 7, susceptibility to
exact