PAS complex
A phosphatidylinositol kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKFYVE in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.
GO:0061695
transferase complex, transferring phosphorus-containing groups
is_a
GO:0098796
membrane protein complex
is_a
GO:0005774
vacuolar membrane
part_of
autophagy-specific phosphatidylinositol 3-kinase complex
related
SPAC1093.03 SPBC3E7.01 SPBP8B7.13 SPBC25H2.03