epsilon DNA polymerase complex
A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.
GO:0042575
DNA polymerase complex
is_a
GO:0140513
nuclear protein-containing complex
is_a
GO:0000228
nuclear chromosome
part_of
DNA polymerase epsilon complex
exact
SPCC16C4.22 SPBP8B7.14c SPBC25H2.13c SPBC3D6.09