malignant pleural mesothelioma
A malignant neoplasm that arises from mesothelial cells in the pleura and shows a diffuse growth pattern. It arises on the parietal and sometimes visceral pleura as multiple small nodules that later become confluent and invade the chest wall adipose tissue and muscle. Asbestos exposure is the main cause for the development of pleural malignant mesothelioma. It usually affects patients over sixty years of age. The latency period is long. Patients usually present with pleural effusion, dyspnea and chest wall pain. Additional signs and symptoms include chills, sweating, weight loss, and weakness. Morphologic variants include epithelioid, desmoplastic, sarcomatoid, and biphasic mesothelioma. The clinical course is usually aggressive.
MONDO:0003308
pleural mesothelioma
is_a
MONDO:0006292
malignant mesothelioma
is_a
MONDO:0006294
pleural cancer
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malignant mesothelioma of pleura
exact
malignant mesothelioma of the pleura
exact
malignant pleural mesothelioma
exact
pleura mesothelioma
broad
pleural diffuse malignant mesothelioma
exact
pleural malignant mesothelioma
exact