Notch receptor processing, ligand-independent
The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.
GO:0016485
protein processing
is_a
GO:0007220
Notch receptor processing
part_of
Notch S1 cleavage
narrow