carcinoid heart disease
Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.
MONDO:0005267
heart disorder
is_a
carcinoid heart disease
exact
carcinoid heart diseases
related
heart disease, carcinoid
related
heart diseases, carcinoid
related