cytoplasmic SCF ubiquitin ligase complex
A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
GO:0000153
cytoplasmic ubiquitin ligase complex
is_a
GO:0019005
SCF ubiquitin ligase complex
is_a
cytoplasmic SCF complex
exact
cytoplasmic Skp1/Cul1/F-box protein complex
exact
cytoplasmic cullin complex
exact