gastrointestinal stromal tumor
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract, typically presenting in adults over the age of 40 (mean age 63), and only rarely in children, in various regions of the GI tract, most commonly the stomach or small intestine but also less commonly in the esophagus, appendix, rectum and colon. GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass, blood in stool, and intestinal obstruction. GISTs can also be seen in familial syndromes such as Carney triad and neurofibromatosis type 1.
MONDO:0003847
hereditary disease
is_a
MONDO:0018506
mesenchymal tumor of small intestine
is_a
GIST
exact
Gastrointestinal Stromal Tumors
exact
gastrointestinal stromal neoplasm
exact
gastrointestinal stromal sarcoma
exact
gastrointestinal stromal tumor
exact
gastrointestinal stromal tumor (gist)
exact
gastrointestinal stromal tumor, familial, isolated cases
exact
gastrointestinal stromal tumor, isolated cases
exact
gastrointestinal stromal tumors
related
gastrointestinal stromal tumour (gist)
exact
gastrointestinal stromal tumours
related
gist
exact
SPAC140.01 SPCC330.12c