Rab geranylgeranyltransferase activity
Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.
GO:0004661
protein geranylgeranyltransferase activity
is_a
GGTase-II activity
exact
GGTaseII activity
exact
Rab-protein geranylgeranyltransferase activity
exact
RabGGTase activity
exact
geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity
exact
protein geranylgeranyltransferase type II activity
exact
type II protein geranyl-geranyltransferase activity
related
SPAPB1A10.04c SPAC167.02 SPCC1620.05