Knl1/Spc105 complex
A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It is involved in kinetochore-microtubule binding, recruiting microtubule binding outer kinetochore subunits. It is essential for kinetochore binding by components of the spindle assembly checkpoint. In humans, budding and fission yeast, it consists of KNL1/ZWINT, Spc105p/Kre28p and Spc7/Sos1, members of the Panther PTHR28260 and PTHR37329 families, respectively.
GO:0032991
protein-containing complex
is_a
GO:0000940
outer kinetochore
part_of
KNL-1 complex
exact
KNL1 complex
exact
Spc105 complex
exact
Spc105p/Kre28p complex
exact
SPAPB17E12.06 SPCC1020.02