hyperinsulinemic hypoglycemia
An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the pancreas and congenital hyperinsulinism. It is due to focal hyperplasia of pancreatic islet cells budding off from the ductal structures and forming new islets of langerhans. Mutations in the islet cells involve the potassium channel gene kcnj11 or the atp-binding cassette transporter gene abcc8, both on chromosome 11.
MONDO:0005151
endocrine system disorder
is_a
MONDO:0019214
inborn carbohydrate metabolic disorder
is_a
hyperinsulinemia hypoglycemia
exact
hyperinsulinemic hypoglycemia (disease)
exact
SPAC4F8.07c SPAC688.09 SPAC24H6.04 SPCC622.12c SPCC132.04c