anaphase-promoting complex
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
GO:0000152
nuclear ubiquitin ligase complex
is_a
GO:0031461
cullin-RING ubiquitin ligase complex
is_a
APC
broad
anaphase promoting complex
exact
cyclosome
exact
SPBC83.04 SPBC106.09 SPBC1198.12 SPAC343.03 SPAC27D7.05c SPBC28E12.01c SPAC6F12.14 SPAC23C11.12 SPAC959.09c SPBP23A10.04 SPAC821.08c SPBC1A4.01 SPAC19G12.01c SPAC6F12.15c SPAC17C9.01c