pyruvate dehydrogenase (acetyl-transferring) activity
Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H+ = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.
GO:0016624
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
is_a
MtPDC (mitochondrial pyruvate dehydogenase complex) activity
narrow
PDH
related
pyruvate dehydrogenase (lipoamide) activity
exact
pyruvate dehydrogenase complex activity
related
pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
related
pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity
related
SPBC30D10.13c SPAC26F1.03