diphthine synthase activity
Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 H+ + 3 S-adenosyl-L-homocysteine.
GO:0008276
protein methyltransferase activity
is_a
GO:0008757
S-adenosylmethionine-dependent methyltransferase activity
is_a
S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity
related
S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity
related
diphthine methyltransferase activity
related