3-isopropylmalate dehydrogenase activity
Catalysis of the reaction: (2R,3S)-3-isopropylmalate + NAD+ = 4-methyl-2-oxopentanoate + CO2 + NADH.
GO:0016616
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a
(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity
related
3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity
related
IMDH activity
related
IPMDH
related
beta-IPM dehydrogenase activity
related
beta-isopropylmalate dehydrogenase activity
related
beta-isopropylmalic enzyme
related
threo-Ds-3-isopropylmalate dehydrogenase activity
related
SPBC1A4.02c