carcinoid tumor
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.
MONDO:0019496
neuroendocrine neoplasm
is_a
NET G1
exact
carcinoid
exact
carcinoid tumor
exact
carcinoid tumor (disease)
exact
carcinoid tumour (disease)
exact
neuroendocrine neoplasm G1
exact
neuroendocrine tumor G1
exact
neuroendocrine tumour G1
exact