G protein-coupled receptor signaling pathway
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
GO:0007165
signal transduction
is_a
G protein coupled receptor protein signaling pathway
exact
G protein coupled receptor protein signalling pathway
exact
G-protein coupled receptor protein signal transduction
exact
G-protein coupled receptor protein signaling pathway
exact
G-protein coupled receptor signaling pathway via GPCR dimer
narrow
G-protein coupled receptor signalling pathway
exact
G-protein-coupled receptor protein signalling pathway
exact
GPCR signaling pathway
exact
GPCR signalling pathway
exact
dimeric G-protein coupled receptor signaling pathway
narrow
dimeric G-protein coupled receptor signalling pathway
narrow
SPBC36.12c SPBC106.10 SPBC215.04 SPAC22F3.12c SPBC24C6.06 SPAC8C9.03 SPCC306.09c SPBC29B5.01 SPAC11H11.04 SPAC3F10.10c SPCC1753.02c SPAC926.04c SPBC19C7.03 SPAC21E11.03c SPAC1B9.02c SPBC3E7.04c SPAC23H3.13c SPCC285.09c SPBC21C3.20c SPBC32H8.07