ripoptosome
A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
GO:1902494
catalytic complex
is_a
GO:0005829
cytosol
part_of
TNFR1 complex II
narrow
Tnfr1-CII
narrow
necrosome
related