prefoldin complex
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
GO:0032991
protein-containing complex
is_a
GIM complex
narrow
SPBC215.02 SPAC227.10 SPAC3H8.07c SPAC227.05 SPAC3A11.13 SPBC1D7.01