susceptibility to respiratory infections associated with CD8alpha chain mutation
Susceptibility to respiratory infections associated with CD8 alpha chain mutation is a rare primary immunodeficiency due to a defect in adaptive immunity characterized by the absence of CD8+ T cells with normal immunoglobulin and specific antibody titres in blood and susceptibility to recurrent respiratory bacterial and viral infections. Symptom severity range from fatal respiratory insufficiency to mild or asymptomatic phenotypes.
MONDO:0018814
non-SCID combined immunodeficiency
excluded_subClassOf
MONDO:0020573
inherited disease susceptibility
is_a
familial CD8 deficiency
exact
susceptibility to respiratory infections associated with CD8alpha chain mutation
exact