hydroxymethylglutaryl-CoA reductase (NADPH) activity
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.
GO:0016616
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
is_a
3-hydroxy-3-methylglutaryl-coenzyme A reductase activity
broad
HMG-CoA reductase activity
broad
hydroxymethylglutaryl-CoA reductase activity
related
SPCC162.09c