aconitate hydratase activity
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
GO:0016836
hydro-lyase activity
is_a
aconitase activity
exact
cis-aconitase activity
related
citrate hydro-lyase activity
broad
citrate(isocitrate) hydro-lyase (cis-aconitate-forming)
related
citrate(isocitrate) hydro-lyase activity
related
SPAC24C9.06c SPBP4H10.15