bilateral generalized polymicrogyria
Bilateral generalized polymicrogyria is a rare neurological disorder that affects the cerebral cortex (the outer surface of the brain). This is the most widespread form of polymicrogyria and typically affects the entire surface of the brain. Signs and symptoms include severe intellectual disability, problems with movement, and seizures that are difficult or impossible to treat. While the exact cause of bilateral generalized polymicrogyria is not fully understood, it is thought to be due to improper brain development during embryonic growth. Most cases appear to follow an autosomal recessive pattern of inheritance. Treatment is based on the signs and symptoms present in each person.
MONDO:0017091
bilateral polymicrogyria
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MONDO:0018764
microcephalic primordial dwarfism due to RTTN deficiency
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MONDO:0100545
hereditary neurological disease
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MSSP
related
PMGYS
related
bilateral generalized polymicrogyria
exact
microcephaly, short stature, and polymicrogyria with seizures
exact
polymicrogyria with seizures
related