SCF ubiquitin ligase complex
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
GO:0031461
cullin-RING ubiquitin ligase complex
is_a
CDL1 complex
exact
CRL1 complex
exact
Cul1-RING ubiquitin ligase complex
exact
SCF complex
exact
SCF complex substrate recognition subunit
narrow
Skp1/Cul1/F-box protein complex
exact
cullin-RING ligase 1
exact
SPBC25B2.11 SPBC1734.14c SPBC12D12.08c SPBC1718.01 SPAC23H4.18c SPAC17G6.12 SPAC13D6.01 SPAC6F6.02c SPCC330.02 SPCC1827.08c SPAC57A10.05c SPAC4D7.03 SPBC409.05 SPBC336.01 SPAC29E6.01