nuclear receptor activity
A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus.
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
is_a
GO:0038023
signaling receptor activity
is_a
GO:0098531
ligand-modulated transcription factor activity
is_a
1,25-(OH)2D3 receptor activity
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9-cis retinoic acid receptor activity
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RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
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RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding
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RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
exact
RXR
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androgen receptor activity
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calcitriol receptor activity
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ecdysteroid hormone receptor activity
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estrogen nuclear receptor activity
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glucocorticoid receptor activity
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juvenile hormone receptor activity
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ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
exact
ligand-dependent nuclear receptor activity
related
ligand-dependent transcription factor activity
related
nuclear hormone receptor
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retinoic acid receptor activity
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retinoid-X receptor activity
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thyroid hormone receptor activity
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vitamin A receptor activity
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vitamin D receptor activity
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vitamin D3 receptor activity
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