miRNA-mediated gene silencing by mRNA destabilization
An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.
GO:0035195
miRNA-mediated post-transcriptional gene silencing
is_a
GO:0061157
mRNA destabilization
is_a
deadenylation involved in gene silencing by miRNA
related
gene silencing by mRNA cleavage
broad
gene silencing by miRNA, mRNA cleavage
exact
mRNA cleavage involved in gene silencing by miRNA
exact
mRNA cleavage involved in gene silencing by microRNA
exact
mRNA deadenylation-mediated gene silencing by miRNA
related
mRNA destabilization-mediated gene silencing by miRNA
exact
miRNA-mediated gene silencing by mRNA deadenylation
related
miRNA-mediated gene silencing, mRNA cleavage
exact