exosome (RNase complex)
A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
GO:1905354
exoribonuclease complex
is_a
GO:0005622
intracellular anatomical structure
part_of
exosome (ribonucleasease complex)
exact
exosome multienzyme ribonuclease complex
exact
SPBC16G5.10 SPAC3G9.10c SPBC115.01c SPAC1F3.01 SPBC26H8.10 SPAC2F7.14c SPBC17D1.03c SPBC211.08c SPAC22A12.12c SPCC1840.11 SPACUNK4.11c SPCC1739.07 SPCC757.08