isotype switching
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
GO:0002204
somatic recombination of immunoglobulin genes involved in immune response
is_a
GO:0002312
B cell activation involved in immune response
is_a
class switch recombination
exact
class switching
exact
isotype switch recombination
exact