NuRD complex
An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.
GO:0000118
histone deacetylase complex
is_a
GO:0005667
transcription regulator complex
is_a
GO:0090545
CHD-type complex
is_a
Mi-2 complex
narrow
NRD complex
exact
nucleosome remodeling and histone deacetylation complex
exact
SPBC2D10.17 SPBC800.03 SPBP35G2.10 SPAC1B3.17