familial Alzheimer disease
A degenerative disease of the brain that causes gradual loss of memory, judgment, and the ability to function socially. About 25% of all Alzheimer disease is familial (more than 2 people in a family have AD). When Alzheimer disease begins before 60 or 65 years of age (early-onset AD) about 60% of the cases are familial (also known as Early-onset familial AD). These cases appear to be inherited in an autosomal dominant manner.
MONDO:0004975
Alzheimer disease
is_a
MONDO:0015547
hereditary dementia
is_a
MONDO:0024237
inherited neurodegenerative disorder
is_a
Alzheimer disease, familial
exact
FAD
exact
GARD:0000632
exact
SPBC16C6.06 SPAC11E3.06 SPBC19F8.03c SPCC16C4.11 SPBC19G7.06 SPBC21D10.12 SPACUNK4.12c