canonical Wnt signaling pathway
A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0016055
Wnt signaling pathway
is_a
Wnt receptor signaling pathway through beta-catenin
exact
Wnt receptor signaling pathway via beta-catenin
exact
Wnt receptor signalling pathway through beta-catenin
exact
canonical Wnt receptor signaling pathway
exact
canonical Wnt-activated signaling pathway
exact
frizzled-1 receptor signaling pathway
narrow