Lynch syndrome 1
An autosomal dominant hereditary neoplastic syndrome caused by pathogenic variants in the MSH2 mismatch repair gene. It is characterized by an increased risk of colorectal cancer in the absense of extensive polyposis, endometrial, ovarian, gastric, small intestinal, and urinary tract cancers, often occuring at younger ages.
MONDO:0005835
Lynch syndrome
is_a
COCA1
related
HNPCC1
exact
Hereditary non-polyposis colon cancer type 1
exact
Lynch 1 syndrome
exact
Lynch syndrome 1
exact
Lynch syndrome type 1
exact
MSH2-related Lynch syndrome
exact
familial non-polyposis colon cancer type 1
exact
hereditary nonpolyposis colorectal cancer type 1
exact
SPBC1703.04 SPBC19G7.01c