obsolete adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate (obsolete GO:0086024)
OBSOLETE. An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.
Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate
exact
If activation by beta-adrenergic receptor signaling pathway
related
activation of funny current by beta-adrenergic receptor signaling pathway
related
adenylate cyclase-activating cardiac adrenergic receptor signaling pathway
related
adrenergic receptor signaling pathway involved in positive regulation of heart rate
broad
adrenergic receptor signalling pathway involved in positive regulation of heart rate
broad
beta adrenergic receptor signaling pathway involved in positive regulation of heart rate
narrow