IKBKG-related immunodeficiency with or without ectodermal dysplasia
Any recessive immunodeficiency (ID), with or without ectodermal dysplasia (EDA), in which the cause of the disease is mutation in the IKBKG gene. ID/EDA-ID patients, always males, are hemizygous for an IKBKG (NEMO) mutation that preserves residual NF-κB activation (hypomorphic mutations) and may also present with osteopetrosis and lymphoedema (OL-EDA-ID).
MONDO:0021094
immunodeficiency disease
is_a
NEMO related ID/EDA-ID
exact