double-strand break repair via alternative nonhomologous end joining
An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.
GO:0006303
double-strand break repair via nonhomologous end joining
is_a
A-NHEJ
related
MMEJ
related
alt-NHEJ
related
double-strand break repair via microhomology-mediated end joining
exact