thrombophilia due to activated protein C resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
MONDO:0002242
coagulation protein disease
is_a
MONDO:0100240
inherited thrombophilia
is_a
APC resistance
related
THPH2
related
resistance, APC
related
thrombophilia 2 due to activated protein C resistance
exact
thrombophilia due to activated protein C resistance
exact