basal-like breast carcinoma
A biologic subset of breast carcinoma defined by high expression of genes characteristic of basal epithelial cells, including KRT5 and KRT17, annexin 8, CX3CL1, and TRIM29, and usually by lack of expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It is the most common subtype of breast cancer associated with BRCA1 mutations, and is associated with a poor prognosis.
MONDO:0004953
invasive ductal breast carcinoma
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MONDO:0005494
triple-negative breast carcinoma
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basal-like breast cancer
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basal-like breast carcinoma
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basal-like subtype of breast carcinoma
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