T-B- severe combined immunodeficiency
T-B- severe combined immunodeficiency (SCID) is a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T and B lymphocytes, resulting in recurrent early-onset severe respiratory viral, bacterial or fungal infections, diarrhea and failure to thrive. Hypersensitivity to ionizing radiation is a characteristic feature of some of its sub-types.
MONDO:0015974
severe combined immunodeficiency
is_a
T-B- SCID
exact
SPCC1183.05c SPBC1198.02 SPAC4G9.03 SPCC24B10.14c