PCSK9-LDLR complex
A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.
GO:0032991
protein-containing complex
is_a
PCSK9.LDLR complex
exact
PCSK9/LDL-R complex
exact
PCSK9:EGF-A complex
related
PCSK9:low-density lipoprotein receptor complex
exact