immunotactoid or fibrillary glomerulopathy
A group of very rare glomerular diseases, composed of immunotactoid glomerulopathy (ITG) and non-amyloid fibrillary glomerulopathy (non-amyloid FGP), that are characterized by mesangial deposition of monoclonal microtubular or polyclonal fibrillar deposits. Both present clinically with nephrotic range proteinuria, hematuria and renal insufficiency leading to renal failure in many cases. ITG is more likely to manifest with underlying lymphoproliferative disease, hypocomplementemia, dysproteinemia, monoclonal gammopathy or occult cryoglobulinemia. Non-amyloid FGP is 10 times more frequent than ITG.
MONDO:0019724
obsolete secondary glomerular disease (obsolete MONDO:0019724)
excluded_subClassOf
MONDO:0019722
glomerular disorder
is_a
Immunotactoid or fibrillary glomerulonephritis
exact
fibrillary glomerulonephritis and immunotactoid glomerulopathy
related