acute monocytic leukemia
Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness. Specific features of AML-M5 include hyperleukocytosis, propensity for extramedullary infiltrates, coagulation abnormalities including disseminated intravascular coagulation and neurological disorders. Leukemia cutis and gingival infiltration can also be seen. A characteristic translocation observed in AML-M5 is t(9;11).
MONDO:0011118
bilineal acute myeloid leukemia
excluded_subClassOf
MONDO:0004600
monocytic leukemia
is_a
MONDO:0018874
acute myeloid leukemia
is_a
AML M5
exact
AML-M5
related
acute monoblastic leukaemia
related
acute monoblastic leukaemia and acute monocytic leukaemia
exact
acute monoblastic leukemia
related
acute monoblastic/monocytic leukaemia
related
acute monoblastic/monocytic leukemia
related
acute monocytic leukaemia (FAB M5B)
exact
acute monocytic leukaemia (FAB M5b)
exact
acute monocytic leukemia
exact
acute monocytic leukemia (FAB M5B)
exact
acute monocytic leukemia (FAB M5b)
exact
acute monocytic leukemia, morphology (morphologic abnormality)
exact
acute myeloblastic leukaemia type 5
related
acute myeloblastic leukemia type 5
related
leukemia, monocytic, malignant
exact
monocytic leukaemia
broad
monocytic leukemia
broad
monocytic leukemia, acute
exact