progressive external ophthalmoplegia
A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)
MONDO:0002320
congenital nervous system disorder
is_a
MONDO:0003425
ophthalmoplegia
is_a
MONDO:0009637
inborn mitochondrial myopathy
is_a
MONDO:0100545
hereditary neurological disease
is_a
chronic progressive external ophthalmoplegia [ambiguous]
exact
progressive external ophthalmoplegia
exact
SPAC1F7.05 SPCC24B10.22 SPBC16D10.04c SPBC336.06c SPBC25D12.04 SPBC16G5.12c SPBC530.10c