acute myeloid leukemia with CEBPA somatic mutations
Acute myeloid leukemia with CEBPA somatic mutations is a subtype of acute myeloid leukemia with recurrent genetic abnormalities, characterized by clonal proliferation of myeloid blasts harboring somatic mutations of the CEBPA gene in the bone marrow, blood and, rarely, other tissues. It can present with anemia, thrombocytopenia, and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly).
MONDO:0018874
acute myeloid leukemia
is_a
AML with CEBPA somatic mutations
exact
AML with mutated CEBPA
exact
acute myeloid Leukaemia with mutated CEBPA
exact
acute myeloid Leukaemia with non-germline mutated CEBPA
exact
acute myeloid Leukemia with mutated CEBPA
exact
acute myeloid Leukemia with non-germline mutated CEBPA
exact
non-familial acute myeloid leukaemia with mutated CEBPA
exact
non-familial acute myeloid leukemia with mutated CEBPA
exact