piRNA-mediated gene silencing by mRNA destabilization
A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping.
GO:0035194
regulatory ncRNA-mediated post-transcriptional gene silencing
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GO:0061157
mRNA destabilization
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