OBSOLETE SO:1000061 sequence_variant_causing_nonconservative_missense_codon_change_in_transcript (obsolete SO:1000061)
The amino acid change following from the codon change changes the gross properties (size, charge, hydrophobicity) of the amino acid in that position.
mutation causing nonconservative missense codon change in transcript
related
sequence variant causing nonconservative missense codon change in transcript
exact