DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
GO:0003916
DNA topoisomerase activity
is_a
GO:0008094
ATP-dependent activity, acting on DNA
is_a
DNA topoisomerase (ATP-hydrolysing)
related
DNA topoisomerase II
narrow
DNA topoisomerase II activity
narrow
DNA topoisomerase IV activity
narrow
DNA topoisomerase type II activity
exact
deoxyribonucleate topoisomerase
broad
deoxyribonucleic topoisomerase activity
broad
topoisomerase
broad
topoisomerase II
narrow
type II DNA topoisomerase activity
related
SPBC1A4.03c SPAC17A5.11