yolk sac tumor
A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.
MONDO:0003578
extragonadal nonseminomatous germ cell tumor
is_a
endodermal sinus neoplasm
exact
endodermal sinus tumor
exact
hepatoid yolk sac tumor
exact
infantile embryonal carcinoma
narrow
yolk SAC tumor, malignant
exact
yolk Sac neoplasm
exact
yolk Sac tumor
exact
yolk Sac tumor site unspecified
exact
yolk Sac tumour site unspecified
exact
yolk sac tumor
exact