toluene embryopathy
Toluene embryopathy is a neurodevelopmental teratologic syndrome due to prenatal exposure to toluene. The disease is characterized by prematurity, low birth weight, dysmorphic features (short palpebral fissures, deep set eyes, low set ears, mid-facial hypoplasia, flat nasal bridge, thin upper lip, micrognathia, spatulate fingertips and small fingernails), central nervous system dysfunctions (intellectual disability, microcephaly, language impairment, hyperactivity, visual dysfunction) and postnatal growth delay. Prenatal exposure to toluene occurs as a result of incidental occupational exposure or solvent abuse during pregnancy. The features of toluene embryopathy often overlap with those seen in fetal alcohol syndrome.
MONDO:0016677
toxic or drug-related embryofetopathy
is_a
MONDO:0700092
neurodevelopmental disorder
is_a
Hersh Podruch Weisskopk syndrome
related
microcephaly, central nervous system dysfunction, minor craniofacial and limb anomalies, and variable growth deficiency
related
toluene embryopathy
exact