hyper-IgM syndrome type 1
The X-linked variant of the Hyper-IgM syndrome. The affected individuals are virtually always male, because males only have one X chromosome, received from their mothers. Their mothers are not symptomatic, even though they are carriers of the allele, because the trait is recessive. Male offspring of these women have a 50% chance of inheriting their mother's mutant allele.
MONDO:0000425
X-linked disease
is_a
MONDO:0003947
hyper-IgM syndrome
is_a
HIGM
related
HIGM1
exact
Hyper IgM Syndromes
exact
IHIS
related
X-linked hyper IgM syndrome
related
X-linked hyper-IgM syndrome
exact
XHIGM
exact
XHIM
related
hyper IgM immunodeficiency, X-linked
related
hyper IgM syndrome
related
hyper IgM syndrome 1
related
hyper-IgM syndrome due to CD40 ligand deficiency
exact
hyper-IgM syndrome due to CD40L deficiency
exact
hyper-IgM syndrome type 1
exact
hyper-IgM syndrome, X-linked
exact
hyperimmunoglobulin M syndrome
exact
immunodeficiency with hyper IgM type 1
related
immunodeficiency with hyper-IgM, type 1
related
immunodeficiency, X-linked, with hyper-IgM, X-linked recessive
exact