severe combined immunodeficiency
Severe combined immunodeficiency (SCID) comprises a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes resulting in early-onset severe respiratory infections and failure to thrive. They are classified according to immunological phenotype into SCID with absence of T cells but presence of B cells (T-B+ SCID) or SCID with absence of both (T-B- SCID). Both of these groups include several forms, with or without natural killer (NK) cells.
MONDO:0015131
combined immunodeficiency
is_a
SCID
exact
severe combined immunodeficiency
exact
severe combined immunodeficiency (disease)
exact
severe combined immunodeficiency disease
exact
SPCC1183.05c SPBC1198.02 SPCC24B10.14c SPAC4G9.03 SPAC23C4.02