cytosolic [4Fe-4S] assembly targeting complex
A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in the cytoplasm and nucleus. In humans it consists of MMS19, CIAO1, CIAO2A/CIAO2B, CIAO3. MMS19, CIAO1 and CIAO2A/CIAO2B form a tight 'core' complex, whereas CIAO3 is an 'external' component of this complex.
GO:0140535
intracellular protein-containing complex
is_a
GO:1990229
iron-sulfur cluster assembly complex
is_a
CIA complex
broad
CIA targeting complex
exact
cytosolic iron-sulfur protein assembly complex
related
SPAC144.16 SPCC1450.10c SPAC806.02c SPAC1071.02