oxidized purine nucleobase lesion DNA N-glycosylase activity
Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
GO:0000702
oxidized base lesion DNA N-glycosylase activity
is_a
2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity
related
2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity
related
8-oxoguanine DNA glycosylase activity
broad
DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]
related
DNA glycosylase/AP-lyase activity
broad
DNA glycosylase/beta-lyase activity
broad
DNA-formamidopyrimidine glycosylase activity
related
Fapy-DNA glycosylase activity
related
Fpg protein
related
bifunctional DNA glycosylase activity
broad
deoxyribonucleate glycosidase activity
related
formamidopyrimidine-DNA glycosylase activity
related
oxidized purine base lesion DNA N-glycosylase activity
exact
purine-specific oxidized base lesion DNA N-glycosylase activity
related
SPAC30D11.07 SPAC26A3.02