undifferentiated high grade pleomorphic sarcoma of bone
A rare, high-grade pleomorphic malignant neoplasm arising from the bone. It usually presents with pain which may or may not be associated with swelling in the affected area. It is characterized by the presence of spindle-shaped cells, polygonal or epithelioid cells, multinucleated giant cells, and inflammatory cells. The neoplastic cells exhibit nuclear pleomorphism and high mitotic activity. It metastasizes frequently, most often in the lungs.
MONDO:0002142
undifferentiated pleomorphic sarcoma
excluded_subClassOf
MONDO:0009807
osteosarcoma
excluded_subClassOf
MONDO:0021054
bone sarcoma
is_a
malignant bone fibrous histiocytoma
exact
malignant fibrous histiocytoma of bone
exact
malignant fibrous histiocytoma of the bone
exact
undifferentiated high grade pleomorphic sarcoma
exact
undifferentiated high grade pleomorphic sarcoma of bone
exact
undifferentiated high-grade pleomorphic sarcoma
exact