keratolytic winter erythema
Keratolytic winter erythema is a rare epidermal disease, characterized by recurrent centrifugal palmoplantar peeling and erythema presenting seasonal variation (cold weather). Skin lesions may spread to the dorsum of hands and feet and to the interdigital spaces. Lower legs, knees and thighs may also be involved. Episodes may be preceded by itch and hyperhidrosis. Skin biopsy reveals an epidermal spongiosis with clefting in the stratum corneum, followed by regrowth. Keratolytic winter erythema follows an autosomal dominant mode of transmission.
MONDO:0019268
epidermal disease
is_a
Erythrokeratolysis hiemalis
exact
Erythrokeratolysis hiemalis ichthyosis
related
KWE
related
Oudtshoorn disease
exact
Oudtshoorn skin
related
keratolytic winter erythema
exact