congenital fibrinogen deficiency
Congenital deficiencies of fibrinogen are coagulation disorders characterized by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen. Afibrinogenemia (complete absence of fibrinogen) and hypofibrinogenemia (reduced plasma fibrinogen concentration) correspond to quantitative anomalies of fibrinogen while dysfibrinogenemia corresponds to a functional anomaly of fibrinogen. Hypo- and dysfibrinogenemia may be frequently combined (hypodysfibrinogenemia).
MONDO:0002242
coagulation protein disease
is_a
MONDO:0002243
hemorrhagic disease
is_a
congenital fibrinogen deficiency
exact
fibrinogen deficiency, congenital
related