Gi/o-coupled serotonin receptor activity
Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.
GO:0004993
G protein-coupled serotonin receptor activity
is_a
5-HT1 receptor activity
exact
serotonin receptor activity, coupled via Gi/o
exact