intestinal disaccharidase deficiency
Inherited or acquired disorders of sugar metabolism. Deficiencies of lactase, maltase or sucrase-isomaltase usually occur irreversibly and independent of one another. Congenital deficiencies are rare whereas acquired deficiencies are more common and may be seen following intestinal mucosal brush-border injury. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following dietary intake of lactose, maltose or sucrose. The clinical course leads to malabsorption of disaccharides which has implications for normal growth and development if manifested at an early age.
MONDO:0019214
inborn carbohydrate metabolic disorder
excluded_subClassOf
MONDO:0020598
malabsorption syndrome
is_a
MONDO:0037792
carbohydrate metabolism disease
is_a
intestinal disaccharidase deficiency and disaccharide malabsorption
exact
SPAC1039.11c SPAPB24D3.10c SPAC30D11.01c