fatty acid elongase activity
Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.
GO:0016747
acyltransferase activity, transferring groups other than amino-acyl groups
is_a
ELOVL
exact
condensing enzyme
broad
elongation of very long chain fatty acids activity
exact
very-long-chain 3-ketoacyl-CoA synthase
exact
very-long-chain 3-oxoacyl-CoA synthase
exact
very-long-chain beta-ketoacyl-CoA synthase
exact
SPAC1639.01c SPAC1B2.03c