blood coagulation, extrinsic pathway
A protein activation cascade that initiates blood coagulation, starting with a signal from tissue factor (TF), a cell-surface, integral-membrane protein, which converts Factor IX to IXa, and Factor IXa converts Factor X to Xa. Factor Xa then initiates the common pathway.
GO:0072376
protein activation cascade
is_a
GO:0072378
blood coagulation, fibrin clot formation
part_of
initiation of blood coagulation cascade, tissue factor pathway
exact