acute megakaryoblastic leukemia
Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia (AML) that occurs predominantly in childhood and particularly in children with Down syndrome (DS-AMKL). Nonspecific symptoms may be irritability, weakness, and dizziness while specific symptoms include pallor, fever, mucocutaneous bleeding, hepatosplenomegaly, neurological manifestations and rarely lymphadenopathy. Acute panmyelosis with myelofibrosis may also be associated with AMKL. In contrast to DS-AMKL (around 80 % survival), non-DS-AMKL is an AML subgroup associated with poor prognosis.
MONDO:0011118
bilineal acute myeloid leukemia
excluded_subClassOf
MONDO:0015667
acute myeloid leukemia by FAB classification
is_a
AMKL
exact
AML M7
exact
FAB M7
exact
acute M7 myeloid leukaemia
exact
acute M7 myeloid leukemia
exact
acute megakaryoblastic leukaemia (FAB type M7)
exact
acute megakaryoblastic leukemia
exact
acute megakaryoblastic leukemia (FAB type M7)
exact
acute megakaryoblastic leukemia, FAB M7
exact
acute megakaryocytic leukaemia
exact
acute megakaryocytic leukemia
exact
acute megakaryocytic leukemias
exact
acute myeloblastic leukaemia type 7
related
acute myeloblastic leukemia type 7
related
acute myeloid leukaemia M7
exact
acute myeloid leukemia M7
exact
leukemia, megakaryocytic, malignant
exact
megakaryocytic leukaemia
related
thrombocytic leukemia
exact