oxoglutarate dehydrogenase complex
A multi-enzyme complex that catalyzes the oxidative decarboxylation of alpha-ketoglutarate (also known as 2-oxoglutarate) to form succinyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.
GO:0045239
tricarboxylic acid cycle heteromeric enzyme complex
is_a
GO:0045240
alpha-ketoacid dehydrogenase complex
is_a
GO:1990234
transferase complex
is_a
KGDHC
exact
alpha-ketoglutarate dehydrogenase complex
exact
dihydrolipoamide S-succinyltransferase complex
exact
SPBC3H7.03c SPBC776.15c SPAC1002.09c SPBC21B10.14