aminoacyl-tRNA synthetase multienzyme complex
A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.
GO:0140535
intracellular protein-containing complex
is_a
GO:1902494
catalytic complex
is_a
aminoacyl-tRNA synthetase complex
exact
multisynthetase complex
exact
SPCC1223.07c SPBC19C7.06 SPBC17A3.04c