increased activation of mitotic spindle assembly checkpoint
A cell cycle checkpoint phenotype in which the mitotic spindle assembly checkpoint is activated more frequently than normal, typically under conditions that do not cause checkpoint activation in wild-type cells. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
FYPO:0000168
abnormal mitotic spindle assembly checkpoint
is_a
activation of mitotic spindle assembly checkpoint increased
exact
increased Bub1 foci
related
increased Mad2 foci
related
increased activation of mitotic cell cycle spindle assembly checkpoint
exact
increased mitotic cell cycle spindle assembly checkpoint activation
exact