AL amyloidosis
AL Amyloidosis is a plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ.
MONDO:0019724
obsolete secondary glomerular disease (obsolete MONDO:0019724)
excluded_subClassOf
MONDO:0005071
nervous system disorder
is_a
MONDO:0006504
acquired metabolic disease
is_a
MONDO:0016330
non-familial hypertrophic cardiomyopathy
is_a
MONDO:0016345
non-familial restrictive cardiomyopathy
is_a
MONDO:0019065
amyloidosis
is_a
Light chain amyloidosis
related
Light-chain amyloidosis
exact
amyloidosis AL
related
amyloidosis primary systemic
related
primary AL amyloidosis
related
primary amyloidosis
exact
primary systemic AL amyloidosis
related
primary systemic amyloidosis
related
systemic AL amyloidsis
related