transforming growth factor beta complex
A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP.
GO:0140392
extracellular protein-containing complex
is_a
TGF-beta complex
exact
TGF-beta dimer
exact
TGFB complex
exact
TGFB dimer
exact
TGFbeta complex
exact
TGFbeta dimer
exact