1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+.
GO:0052742
phosphatidylinositol kinase activity
is_a
phosphatidylinositol 3-kinase activity, class I
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phosphatidylinositol 3-kinase activity, class II
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phosphatidylinositol 3-kinase, class I, catalyst activity
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phosphatidylinositol-4,5-bisphosphate 3-kinase activity
exact
type I phosphoinositide 3-kinase activity
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