DNA 5'-adenosine monophosphate hydrolase activity
Catalysis of the reactions: a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H+; and: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O = a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H+. Nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.
GO:0016462
pyrophosphatase activity
is_a
AMP-removal activity
related
DNA 5'-adenylate hydrolase activity
exact
DNA adenylate hydrolysis activity
broad
DNA de-adenylation
related
DNA deadenylation
related
SPCC18.09c