neonatal-onset developmental and epileptic encephalopathy
A complex neurodevelopmental disorder characterized by a neonatal onset of recurrent seizures, an abnormal neonatal electroencephalographic background with multifocal epileptiform discharges, excessive discontinuity, and/or burst-suppression patterns, and encephalopathy. Seizures may be pharmacoresistant or responsive. Developmental delays persist but vary in severity. In some individuals, subsequent evolution to other epileptic encephalopathy syndromes (e.g. West syndrome) may occur.
MONDO:0100062
genetic developmental and epileptic encephalopathy
is_a
SPCC794.09c SPAC22F8.11 SPBC839.15c SPBC3B8.04c SPAC23C11.09 SPAC23A1.10 SPAC323.06c SPAC1A6.10 SPAC767.01c SPBC12C2.08