agammaglobulinemia
A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes.
MONDO:0002211
B cell deficiency
is_a
Gammaglobulin Deficiency
related
Immunoglobulin Deficiency
related
agammaglobulinemia
exact
antibody Deficiency
related
SPAP8A3.03 SPBC19G7.17 SPBC354.02c