cohesin complex
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
GO:0032991
protein-containing complex
is_a
GO:0005694
chromosome
part_of
14S cohesin
narrow
9S cohesin
narrow
SMC complex
related
SMC/kleisin ring complex
exact
Smc1-Smc3 complex
narrow
cohesin core heterodimer
related
nuclear cohesin complex
related
SPBC29A10.04 SPCC338.17c SPBC29A10.14 SPAC15A10.15 SPAC10F6.09c SPAC17H9.20 SPCC4E9.01c