phosphatidylinositol 3-kinase/protein kinase B signal transduction
An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.
GO:0141124
intracellular signaling cassette
is_a
AKT signal transduction
related
AKT signaling
related
AKT signaling cascade
related
AKT signalling cascade
related
PI3K-PKB/Akt pathway
exact
PI3K/Akt signal transduction
exact
PI3K/PKB signal transduction
exact
PKB signal transduction
related
PKB signaling
related
PKB signaling cascade
related
PKB signalling cascade
related
phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction
exact
protein kinase B signal transduction
related
protein kinase B signaling
related
protein kinase B signaling cascade
related
protein kinase B signalling cascade
related