tricarboxylic acid cycle
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
GO:0044238
primary metabolic process
is_a
GO:0009060
aerobic respiration
part_of
Krebs cycle
exact
TCA cycle
exact
citric acid cycle
exact
oxidative TCA cycle
exact
SPCC1620.08 SPBC3H7.03c SPAC1556.02c SPAC11G7.03 SPAC6C3.04 SPAC16E8.17c SPCC18.18c SPBC21B10.14 SPAC140.01 SPBC776.15c SPBP23A10.16 SPAC24C9.06c SPCC306.08c SPCC330.12c SPBC902.05c SPBP4H10.15 SPAC6G10.08