decreased RNA polymerase II proximal promoter sequence-specific DNA binding
A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. An RNA polymerase II proximal promoter is a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
FYPO:0000658
decreased DNA binding
is_a
decreased transcription factor binding to promoter region
related
reduced RNA polymerase II proximal promoter sequence-specific DNA binding
exact