Tapasin-ERp57 complex
Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.
GO:0098796
membrane protein complex
is_a
GO:0140534
endoplasmic reticulum protein-containing complex
is_a
GO:0042824
MHC class I peptide loading complex
part_of