MAPK cascade
An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
GO:0141124
intracellular signaling cassette
is_a
ERK/MAPK cascade
narrow
MAP kinase cascade
exact
MAP kinase kinase kinase cascade
exact
MAPK signal transduction
exact
MAPK signaling
related
MAPK signalling
related
MAPKKK cascade
exact
MAPKKK cascade during sporulation
narrow
mitogen-activated protein kinase cascade
exact
SPBC32F12.11 SPCC1442.01 SPAC1296.03c SPBC24C6.06 SPCC576.03c SPCC1795.06 SPAC1F3.02c SPBC887.10 SPAC1F5.09c SPBC21.06c SPAC3G9.05 SPBC23G7.08c SPAC19D5.01 SPAC2G11.07c SPAC26F1.10c SPBC409.07c SPBC1D7.05 SPAC23E2.03c SPAC17G8.14c SPAC27E2.09 SPBPJ4664.03 SPCC757.09c SPAC6B12.15 SPAC4A8.03c SPAPB8E5.05 SPAC17H9.09c SPAC9G1.02 SPAC1D4.13 SPAC22F3.12c SPCC645.07 SPBC725.02 SPBC28E12.03 SPCC4F11.02 SPAC7D4.03c SPBC1685.01 SPBC543.07 SPAC24B11.06c SPAC1006.09 SPCC74.06 SPAC513.03 SPAPYUG7.02c SPAC11G7.01 SPAC2F7.03c SPBC12D12.04c SPAC3F10.10c SPAC11H11.04 SPAC31G5.09c SPBC1604.14c SPAC1565.04c SPBC119.08 SPAC1F7.04 SPAC16.01