CDH1-related diffuse gastric and lobular breast cancer syndrome
Germline pathogenic or likely pathogenic variants in the CDH1 gene predispose to hereditary diffuse gastric cancer, a cancer susceptibility syndrome inherited in an autosomal dominant pattern, initially characterized by the increased risk for diffuse gastric cancer (DGC) but subsequently well documented to be associated with lobular breast cancer (LBC) in women.
MONDO:0015356
hereditary neoplastic syndrome
is_a
DGLBC
exact
HDGC
exact
LBC
exact
diffuse gastric and lobular breast cancer syndrome
exact
gastric cancer, familial diffuse breast cancer, lobular
exact
gastric cancer, hereditary diffuse
exact