large cell neuroendocrine carcinoma
A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas.
MONDO:0002120
neuroendocrine carcinoma
is_a
MONDO:0005232
large cell carcinoma
is_a
LCNEC
exact
large cell NEC
exact
large cell neuroendocrine carcinoma
exact
large-cell neuroendocrine carcinoma
exact