Kit signaling pathway
The series of molecular signals initiated by the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.
GO:0007169
cell surface receptor protein tyrosine kinase signaling pathway
is_a
GO:0019221
cytokine-mediated signaling pathway
is_a
GO:0036216
cellular response to stem cell factor stimulus
part_of
Kit signalling pathway
exact
SCF signaling pathway
exact
stem cell factor receptor signaling pathway
exact
stem cell factor signaling pathway
exact