MAP kinase kinase kinase kinase activity
Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.
GO:0004674
protein serine/threonine kinase activity
is_a
MAP4K activity
exact
MAPKKKK
exact