histone H4K20 trimethyltransferase activity
Catalysis of the reaction: L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = 3 H+ + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to the lysine residue at position 20 of the histone H4 protein, producing histone H4K20me3.
GO:0042799
histone H4K20 methyltransferase activity
is_a
histone H4K20 trimethylase activity
exact
histone H4K20 trimethylation
exact
histone lysine N-trimethyltransferase activity (H4-K20 specific)
exact
SPCC4B3.12