lissencephaly spectrum disorders
The term lissencephaly covers a group of rare malformations sharing the common feature of anomalies in the appearance of brain convolutions (characterized by simplification or absence of folding) associated with abnormal organization of the cortical layers as a result of neuronal migration defects during embryogenesis.
MONDO:0000508
syndromic intellectual disability
excluded_subClassOf
MONDO:0002320
congenital nervous system disorder
is_a
MONDO:0021147
disorder of development or morphogenesis
is_a
MONDO:0100545
hereditary neurological disease
is_a
Broad gyri of cerebrum
related
Lissencephaly
exact
large gyri of cerebrum
related
lissencephaly
exact
lissencephaly (disease)
exact
lissencephaly spectrum disorders
exact
macrogyria
related
pachygyria
related
SPCC364.07 SPAC1F12.07 SPCC16C4.11 SPBC651.03c SPBC16A3.15c SPBC26H8.07c SPBC800.05c SPBC32H8.12c