arachidonate 12(S)-lipoxygenase activity
Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
GO:0016702
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
is_a
12-lipoxygenase activity
related
12Delta-lipoxygenase activity
related
12S-lipoxygenase activity
related
C-12 lipoxygenase activity
related
LTA4 synthase activity
related
arachidonate:oxygen 12-oxidoreductase activity
related
delta12-lipoxygenase activity
related
leukotriene A4 synthase
broad