combined pituitary hormone deficiencies, genetic form
Congenital hypopituitarism is characterized by multiple pituitary hormone deficiency, including somatotroph, thyrotroph, lactotroph, corticotroph or gonadotroph deficiencies, due to mutations of pituitary transcription factors involved in pituitary ontogenesis. Congenital hypopituitarism is rare compared with the high incidence of hypopituitarism induced by pituitary adenomas, transsphenoidal surgery or radiotherapy.
MONDO:0002320
congenital nervous system disorder
is_a
MONDO:0005152
hypopituitarism
is_a
MONDO:0015770
congenital hypogonadotropic hypogonadism
is_a
MONDO:0100545
hereditary neurological disease
is_a
familial congenital hypopituitarism
exact
familial hypopituitarism
related
genetic hypopituitarism
exact
multiple pituitary hormone deficiencies, genetic forms
exact
pituitary hormone deficiency, combined
exact