Niemann-Pick disease, type C, dog
A lysosomal storage disease characterised by impaired unesterified cholesterol and sphingomyelin transport and metabolism, resulting in the accumulation of un-esterified cholesterol and glycosphingolipids within late endosomes and lysosomes that occurs in dogs. Affected animals present with hepatosplenomegaly, neurological degeneration and premature death.
MONDO:1010860
lysosomal storage disease, dog
is_a
Niemann-Pick disease, type C1, dog
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