format-version: 1.2
date: 27:02:2013 10:05
saved-by: midori
auto-generated-by: OBO-Edit 2.1-beta13
default-namespace: pb_quiescence
ontology: pb_quiescence

[Term]
id: PBQ:0000001
name: cell quiescence
def: "A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed." [PomBase:mah, PomBase:jb]
comment: Note that terminally differentiated cells in higher eukaryotes are typically quiescent but metabolically active.
synonym: "cellular quiescence" EXACT [PomBase:mah]
synonym: "cell cycle quiescence" RELATED [PomBase:mah]
synonym: "G0 phase" RELATED [PomBase:mah]
synonym: "quiescence" BROAD [PomBase:mah]

[Term]
id: PBQ:0000002
name: cell quiescence following G1 arrest
def: "Cell quiescence, i.e. a specialized resting state in which the cells do not grow or divide, and the gene expression pattern changes globally, that a cell enters following cell cycle arrest in G1. IIn some cell types or under certain conditions, cellular metabolism may proceed." [PomBase:mah]
comment: Note that terminally differentiated cells in higher eukaryotes are typically quiescent but metabolically active.
synonym: "cellular quiescence following G1 arrest" EXACT [PomBase:mah]
synonym: "quiescence following G1 arrest" BROAD [PomBase:mah]
synonym: "G0 phase" RELATED [PomBase:mah]
is_a: PBQ:0000001

[Term]
id: PBQ:0000003
name: cell quiescence following G1 arrest due to nitrogen limitation
def: "Cell quiescence, i.e. a specialized resting state in which the cells do not grow or divide, and the gene expression pattern changes globally, that a cell enters following cell cycle arrest in G1 due to nitrogen limitation. In some cell types or under certain conditions, cellular metabolism may proceed." [PomBase:mah]
comment: Note that this type of cell quiescence has been characterized in fission yeast.
synonym: "cellular quiescence following G1 arrest due to nitrogen limitation" EXACT [PomBase:mah]
synonym: "quiescence following G1 arrest due to nitrogen limitation" BROAD [PomBase:mah]
is_a: PBQ:0000002

[Term]
id: PBQ:0000004
name: cell quiescence following G2 arrest due to glucose limitation
def: "Cell quiescence, i.e. a specialized resting state in which the cells do not grow or divide, and the gene expression pattern changes globally, that a cell enters following cell cycle arrest in G2 due to glucose limitation." [PomBase:mah]
comment: Note that this type of cell quiescence has been characterized in fission yeast.
synonym: "cellular quiescence following G2 arrest due to glucose limitation" EXACT [PomBase:mah]
synonym: "quiescence following G2 arrest due to glucose limitation" BROAD [PomBase:mah]
is_a: PBQ:0000001