format-version: 1.2 data-version: fypo/releases/2025-09-27/fypo-simple-pombase.obo date: 12:05:2020 14:21 saved-by: midori auto-generated-by: OBO-Edit 2.3.1 subsetdef: qc_do_not_annotate "Term not to be used for direct annotation" subsetdef: qc_do_not_manually_annotate "Term not to be used for direct manual annotation" default-namespace: fission_yeast_phenotype remark: svn version: $Revision: 303 $ ontology: fypo/fypo-simple-pombase.obo property_value: http://purl.org/dc/elements/1.1/description "A formal ontology of phenotypes observed in fission yeast." xsd:string property_value: http://purl.org/dc/elements/1.1/title "Fission Yeast Phenotype Ontology (FYPO)" xsd:string property_value: http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/4.0/ property_value: IAO:0000700 FYPO:0000001 property_value: owl:versionInfo "2025-09-27" xsd:string [Term] id: FYPO:0000001 name: phenotype def: "Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast phenotype" EXACT [PomBase:mah] creation_date: 2011-03-16T03:59:25Z [Term] id: FYPO:0000002 name: cell phenotype def: "A phenotype that is observed at the level of an individual cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cell phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype disjoint_from: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2011-03-16T04:25:28Z [Term] id: FYPO:0000003 name: cell population phenotype def: "A phenotype that is observed at the level of a population of cells." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Note: differentium is population level, and may reflect observation conditions. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cell population phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-03-16T04:26:35Z [Term] id: FYPO:0000004 name: cell viability def: "A cell phenotype that consists of the cell's disposition to survive and develop normally." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Viability is usually determined under standard laboratory conditions, i.e. a cell is generally considered viable if it can grow in rich medium under normal conditions such as temperature, pressure, oxygen level, pH, etc. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000005 name: abnormal cell morphology alt_id: FYPO:0000019 def: "A cell phenotype characterized by altered cell morphology, i.e. the size, shape, or structure of the cell is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell morphology, misshapen cells" RELATED [PomBase:mah] synonym: "cellular morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000136 ! cellular physical quality phenotype is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000006 name: abnormal mitotic DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is abnormal. A mitotic DNA damage checkpoint normally regulates progression through the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic DNA damage checkpoint activation" EXACT [PomBase:mah] synonym: "abnormal mitotic DNA damage checkpoint during cellular response to DNA damage" EXACT [PomBase:al] synonym: "abnormal mitotic DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic DNA damage checkpoint defects" EXACT [PomBase:mah] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus during vegetative growth is_a: FYPO:0000643 ! abnormal mitotic DNA integrity checkpoint created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000007 name: abnormal S-phase DNA damage checkpoint alt_id: FYPO:0000195 def: "A mitotic cell cycle checkpoint phenotype in which the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal intra-S DNA damage checkpoint" EXACT [PomBase:mah] synonym: "abnormal mitotic S-phase DNA damage checkpoint" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint activation" RELATED [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "DNA damage checkpoint defects, S-phase" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal mitotic DNA damage checkpoint created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000008 name: abnormal meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination is abnormal. Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes." [GO:0007131, PomBase:mah] synonym: "abnormal meiotic DNA recombination" EXACT [PomBase:mah] synonym: "abnormal reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "DNA recombination defects, meiotic" EXACT [PomBase:mah] synonym: "meiotic recombination: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000063 ! abnormal DNA recombination is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000009 name: abnormal cell adhesion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which adhesion of a cell to a substrate or another cell is abnormal." [PomBase:mah] synonym: "abnormal cell adhesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "adhesion defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001872 ! abnormal cell adhesion created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000010 name: abolished cell-substrate adhesion def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells fail to adhere to a substrate." [PomBase:mah] synonym: "abolished cell-substrate adhesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell-substrate adhesion abolished" EXACT [PomBase:mah] synonym: "cell-substrate adhesion abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000011 name: abnormal cell cycle alt_id: FYPO:0000406 def: "A cellular process phenotype in which a cell does not proceed normally through a cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal cell-division cycle" EXACT [GO:0007049, PomBase:mah] synonym: "cell cycle defects" EXACT [PomBase:mah] synonym: "cell cycle progression: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000631 ! cell cycle phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000012 name: mitotic G2/M phase transition delay alt_id: FYPO:0000205 alt_id: FYPO:0000401 alt_id: FYPO:0000604 alt_id: FYPO:0000605 alt_id: FYPO:0000606 alt_id: FYPO:0000971 def: "A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins later than normal. The duration of G2 phase is thus longer than normal." [PomBase:mah] comment: A G2/M delay may indicate that a checkpoint, such as the DNA replication checkpoint or the G2/M DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "cell cycle progression through the G2/M phase transition: delayed" RELATED [SGD:phenotype_annotation] synonym: "cell cycle, mitotic G2 delay" RELATED [PomBase:mah] synonym: "decreased rate of mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "delayed cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "delayed entry into mitosis" EXACT [PomBase:vw] synonym: "delayed mitotic entry" EXACT [PomBase:vw] synonym: "delayed mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "delayed onset of mitotic M phase" RELATED [PomBase:vw] synonym: "G2/M transition delay during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of mitotic G2 phase" RELATED [PomBase:mah] synonym: "increased duration of mitotic G2 phase during vegetative growth" RELATED [PomBase:mah] synonym: "increased mitotic G2 duration" RELATED [PomBase:mah] synonym: "mitotic cell cycle delay at G2/M transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G2 phase: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in G2 phase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in G2 phase: increased duration" RELATED [SGD:phenotype_annotation] synonym: "mitotic DNA replication checkpoint activated" RELATED [PomBase:mah] synonym: "mitotic G2 delay" RELATED [PomBase:mah] synonym: "mitotic G2/M transition delay" EXACT [PomBase:mah] synonym: "mitotic G2/M transition delay during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic G2/M transition DNA damage checkpoint activated" RELATED [PomBase:mah] synonym: "reduced rate of mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "transient cell cycle arrest at mitotic G2/M phase transition" RELATED [PomBase:mah] synonym: "transient cell cycle arrest in mitotic G2 phase" RELATED [PomBase:mah] is_a: FYPO:0000399 ! abnormal mitotic G2/M phase transition is_a: FYPO:0000409 ! delayed cell cycle phase transition is_a: FYPO:0000563 ! abnormal mitotic G2 phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase is_a: FYPO:0005275 ! abnormal mitotic cell cycle phase transition created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000013 name: T-shaped vegetative cell with normal cell length def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cell length is normal, and a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T." [PomBase:mah, PomBase:vw] comment: One distinction between T-shaped and other branched cells is that in T-shaped cells the new growth zone forms before NETO. A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell morphology, T shaped with normal cell length during vegetative growth" EXACT [PomBase:mah] synonym: "T-shaped cell with normal cell length during vegetative growth" EXACT [PomBase:mah] synonym: "T-shaped vegetative cell with normal cell length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0007379 ! T-shaped vegetative cell created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000014 name: tapered cell def: "A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that the difference between 'tapered cell' (FYPO:0000014) and 'spindle-shaped cell' (FYPO:0007230) is that a tapered cell is narrow at only one end, whereas a spindle-shaped cell is narrow at both ends. synonym: "bottle-shaped cell" EXACT [PomBase:vw] synonym: "cell morphology, bottle/skittle" EXACT [PomBase:mah] synonym: "skittle-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000015 name: branched vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a daughter cell begins to grow from the lateral portion of the long axis of the cell, and at an angle to the septum or cell division site of the mother cell, resulting in the formation of a single cell that has a branch." [PomBase:mah] synonym: "branched cell" EXACT [PomBase:mah] synonym: "branched cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell morphology, branched" EXACT [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000016 name: curved vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] synonym: "cell morphology, curved" EXACT [PomBase:mah] synonym: "comma-shaped cell" EXACT [PomBase:vw] synonym: "curved cell" EXACT [PomBase:mah] synonym: "curved cell during vegetative growth" EXACT [PomBase:mah] synonym: "curved vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000017 name: elongated cell def: "A cell morphology phenotype in which cells are longer than normal, and the length:diameter ratio is greater than normal." [PomBase:mah, PomBase:vw] comment: Note that this term is classified as a type of abnormal cell shape, because wild-type cells are never seen with the proportions (length:diameter ratio) observed in elongated cells. Small cells, in contrast, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. synonym: "cell morphology, elongated cell" EXACT [PomBase:mah] synonym: "long cell" EXACT [PomBase:vw] is_a: FYPO:0006633 ! increased cell length is_a: FYPO:0008096 ! increased cell size relationship: has_part FYPO:0006633 ! increased cell length created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000020 name: pear-shaped cell def: "A cell morphology phenotype in which a cell is shaped in the form of a pear. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PomBase:mah] synonym: "cell morphology, pear shaped" EXACT [PomBase:mah] synonym: "ice cream cone-shaped cell" EXACT [PMID:2236039, PomBase:vw] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000021 name: spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] synonym: "cell morphology, round vegetative cell" RELATED [PomBase:mah] synonym: "cell morphology, rounded vegetative cell" RELATED [PomBase:mah] synonym: "rounded vegetative cell" EXACT [PomBase:mah] synonym: "spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001955 ! spheroid cell is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000022 name: shmoo with long tip def: "A cell morphology phenotype in which a cell forms a mating projection with a longer tip than normal." [PomBase:mah] synonym: "cell morphology, shmoos with long tips" EXACT [PomBase:mah] synonym: "conjugation tube with long tip" EXACT [PomBase:mah] synonym: "long, straight shmoos" EXACT [PomBase:mah] synonym: "mating projection with long tip" EXACT [PomBase:mah] synonym: "straight and long shmoos" EXACT [PMID:28410370] is_a: FYPO:0000357 ! abnormal shmoo morphology created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000023 name: small cell def: "A cell morphology phenotype in which a cell has an abnormally low volume." [PomBase:mah] comment: Note that this term is not classified as a type of abnormal cell shape, small cells, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. Elongated cells, in contrast, have proportions (length:diameter ratio) that are never observed in wild-type cells, and so are classified under both abnormal cell shape and abnormal cell size. synonym: "cell size: decreased" RELATED [SGD:phenotype_annotation] synonym: "decreased cell size" EXACT [PomBase:mah] synonym: "reduced cell size" EXACT [PomBase:mah] is_a: FYPO:0001127 ! abnormal cell size created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000024 name: stubby vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] synonym: "cell morphology, stubby cells" EXACT [PomBase:mah] synonym: "stubby cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "stubby cell during vegetative growth" EXACT [PomBase:mah] synonym: "watermelon-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape is_a: FYPO:0006615 ! increased cell diameter relationship: has_part FYPO:0006615 ! increased cell diameter created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000025 name: swollen cell def: "A cell morphology phenotype in which a cell has a larger volume than normal. In a swollen cell, both length and diameter are greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "cell morphology, swollen cells" EXACT [PomBase:mah] synonym: "enlarged cell" RELATED [PomBase:mah] synonym: "increased cell size" RELATED [PomBase:vw] synonym: "increased cell volume" EXACT [PomBase:mah] synonym: "large cell" RELATED [PomBase:vw] is_a: FYPO:0008096 ! increased cell size created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000026 name: abnormal vegetative cell polarity def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] synonym: "abnormal cell polarity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell polarity during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell polarity process during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity during vegetative growth" EXACT [PomBase:mah] synonym: "cell polarity defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0005568 ! abnormal cell polarity created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000027 name: abnormal cell wall during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cell wall is abnormal." [PomBase:mah] synonym: "abnormal cell wall during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell wall defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000029 name: abnormal chromosome segregation alt_id: FYPO:0000226 def: "A cellular process phenotype in which chromosome segregation is abnormal. Chromosome segregation begins with the alignment of chromosomes at the metaphase plate, includes sister chromatid separation, and ends when chromosomes have completed movement to the spindle poles." [GO:0007059, PomBase:mah] synonym: "centromere function defective" RELATED [PomBase:mah] synonym: "chromosome missegregation" RELATED [PomBase:vw] synonym: "chromosome segregation defects" EXACT [PomBase:mah] synonym: "chromosome segregation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000030 name: abnormal mitotic chromosome congression def: "A cellular process phenotype in which chromosome congression is abnormal during mitosis. Chromosome congression is the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." [GO:0051310, PomBase:mah] synonym: "abnormal chromosome congression at mitotic metaphase plate" EXACT [PomBase:mah] synonym: "abnormal chromosome congression during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromosome congression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic metaphase plate congression" EXACT [GO:0007080] synonym: "chromosome segregation defects, chromosome congression" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000031 name: abnormal mating def: "A cellular process phenotype in which conjugation is abnormal. Conjugation, also known as mating, is a process that results in the union of cellular and genetic information from cells of compatible mating types." [GO:0000747, PomBase:mah] synonym: "abnormal conjugation" EXACT [PomBase:mah] synonym: "abnormal conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "abnormal zygote formation" RELATED [PomBase:mah] synonym: "conjugation defects" EXACT [PomBase:mah] is_a: FYPO:0000301 ! mating phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000032 name: abnormal cytokinesis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis is abnormal. Cytokinesis is part of the cell cycle and results in the division of the cytoplasm of a cell and its separation into two daughter cells." [GO:0000281, PomBase:mah] synonym: "abnormal cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "abnormal cytokinesis" BROAD [PomBase:mah] synonym: "abnormal cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cytokinesis" EXACT [PomBase:mah] synonym: "cytokinesis defects" EXACT [PomBase:mah] synonym: "cytokinesis: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000186 ! abnormal cell division during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000033 name: abnormal actomyosin contractile ring localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring localization is abnormal. Actomyosin contractile ring localization is the part of cytokinesis in which the actomyosin contractile ring is assembled and/or maintained in a specific location." [GO:1902405, PomBase:mah] comment: Note that the location of the contractile ring is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. Consider also annotating to 'abnormal septum site selection' (FYPO:0002154) because if the contractile ring forms in an abnormal location, the septum will also do so. The positions of both the contractile ring and the septum are determined by the processes that select the site of cell division. synonym: "abnormal actomyosin contractile ring localisation" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring localization involved in mitotic cytokinesis" EXACT [GO:1902405, PomBase:mah] synonym: "abnormal actomyosin contractile ring positioning" EXACT [PomBase:vw] synonym: "abnormal cytokinetic contractile ring localization" EXACT [PomBase:vw] synonym: "abnormal mitotic contractile ring localization" EXACT [PomBase:vw] synonym: "cytokinesis defects, misplaced contractile ring" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000034 name: abnormal endocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [GO:0006897, PomBase:mah] synonym: "abnormal actin-mediated endocytosis during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein internalization during vegetative growth" NARROW [PomBase:mah] synonym: "endocytosis defects during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis: abnormal during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport during vegetative growth is_a: FYPO:0003886 ! abnormal endocytosis created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000035 name: growth auxotrophic for arginine def: "Auxotrophy in which a cell is unable to synthesize arginine, and therefore requires arginine in the medium for vegetative cell growth." [PomBase:mah] synonym: "arginine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for arginine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for arginine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000036 name: growth auxotrophic for asparagine def: "Auxotrophy in which a cell is unable to synthesize asparagine, and therefore requires asparagine in the medium for vegetative cell growth." [PomBase:mah] synonym: "asparagine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for asparagine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for asparagine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000037 name: growth auxotrophic for cysteine def: "Auxotrophy in which a cell is unable to synthesize cysteine, and therefore requires cysteine in the medium for vegetative cell growth." [PomBase:mah] synonym: "cysteine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for cysteine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for cysteine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000038 name: growth auxotrophic for ethanolamine def: "Auxotrophy in which a cell is unable to synthesize ethanolamine, and therefore requires ethanolamine in the medium for vegetative cell growth." [PomBase:mah] synonym: "ethanolamine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for ethanolamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for ethanolamine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000039 name: growth auxotrophic for lysine def: "Auxotrophy in which a cell is unable to synthesize lysine, and therefore requires lysine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for lysine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for lysine during vegetative growth" EXACT [PomBase:mah] synonym: "lysine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000040 name: growth auxotrophic for methionine def: "Auxotrophy in which a cell is unable to synthesize methionine, and therefore requires methionine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for methionine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for methionine during vegetative growth" EXACT [PomBase:mah] synonym: "methionine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000041 name: growth auxotrophic for phenylalanine def: "Auxotrophy in which a cell is unable to synthesize phenylalanine, and therefore requires phenylalanine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for phenylalanine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for phenylalanine during vegetative growth" EXACT [PomBase:mah] synonym: "phenylalanine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000042 name: growth auxotrophic for sulfite def: "Auxotrophy in which a cell requires sulfite in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for sulfite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for sulfite during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for sulphite" EXACT [PomBase:mah] synonym: "sulfite auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000043 name: abnormal glucan synthesis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which glucan biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal glucan synthesis during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0007904 ! abnormal glucan synthesis created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000044 name: abnormal negative regulation of transcription by glucose alt_id: FYPO:0000210 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) is abnormal. For example, specific genes that are normally not transcribed in the presence of glucose may be transcribed in the mutant." [GO:0045014, PomBase:mah] synonym: "abnormal glucose repression" EXACT [GO:0045014, PomBase:mah] synonym: "abnormal glucose repression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal negative regulation of transcription by glucose during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of transcription by glucose during vegetative growth" EXACT [PomBase:mah] synonym: "glucose repression defects" EXACT [PomBase:mah] synonym: "glucose-insensitive transcription" RELATED [PomBase:vw] is_a: FYPO:0000624 ! abnormal negative regulation of transcription during vegetative growth is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000045 name: abnormal cell population growth def: "A cell population phenotype in which a population of cells grow abnormally. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "growth defect" RELATED [PomBase:mah] is_a: FYPO:0000139 ! cell population growth phenotype is_a: FYPO:0005447 ! abnormal biological process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000046 name: decreased cell population growth alt_id: FYPO:0000222 def: "A cell population phenotype in which cell population growth is decreased relative to normal. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "aerobic growth defects" RELATED [PomBase:mah] synonym: "decreased aerobic cell population growth" NARROW [PomBase:mah] synonym: "decreased growth" BROAD [PomBase:mah] synonym: "reduced aerobic cell population growth" NARROW [PomBase:mah] synonym: "reduced cell population growth" EXACT [PomBase:mah] synonym: "slow aerobic cell population growth" NARROW [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000047 name: normal cell population growth def: "A cell population phenotype in which a population of cells grow normally (i.e. indistinguishably from wild type). Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "growth normal" BROAD [PomBase:mah] is_a: FYPO:0000139 ! cell population growth phenotype is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000048 name: obsolete invasive growth abolished alt_id: FYPO:0000465 def: "OBSOLETE. A cellular process phenotype in which invasive growth does not occur." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "absent invasive growth" EXACT [PomBase:mah] synonym: "invasive growth abolished during vegetative growth" EXACT [PomBase:mah] synonym: "invasive growth: absent" RELATED [SGD:phenotype_annotation] is_obsolete: true consider: FYPO:0000551 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000049 name: inviable cell def: "A viability phenotype in which a cell is unable to survive under conditions in which wild type cells survive." [PomBase:mah] comment: Viability is usually determined under standard laboratory conditions, i.e. a cell is generally considered inviable if it cannot grow in rich medium under normal conditions such as temperature, pressure, oxygen level, pH, etc. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "lethal in cell" EXACT [PomBase:mah] is_a: FYPO:0000004 ! cell viability created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000050 name: abnormal kinetochore morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the kinetochore is abnormal." [PomBase:mah] comment: Note that an abnormal kinetochore organization process may, but does not necessarily, result in abnormal kinetochore structure. synonym: "abnormal kinetochore morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal kinetochore structure during vegetative growth" NARROW [PomBase:mah] synonym: "kinetochore defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0005646 ! abnormal kinetochore morphology relationship: output_of FYPO:0000807 ! abnormal kinetochore organization created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000051 name: abnormal meiosis alt_id: FYPO:0000738 def: "A cellular process phenotype in which meiosis is abnormal. Meiosis refers specifically to the nuclear division phases of a meiotic cell cycle." [PomBase:mah] synonym: "abnormal meiotic nuclear division" EXACT [GO:0140013] synonym: "meiosis defects" EXACT [PomBase:mah] synonym: "meiosis: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000052 name: abnormal meiotic cell cycle def: "A cellular process phenotype in which a cell does not proceed normally through a meiotic cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "meiotic cell cycle defects" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000054 name: abnormal microtubule cytoskeleton organization alt_id: FYPO:0000053 def: "A phenotype that affects the organization of the microtubule cytoskeleton. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in a physically abnormal microtubule cytoskeleton. synonym: "abnormal microtubule cytoskeleton organisation" EXACT [PomBase:mah] synonym: "abnormal microtubule organisation" RELATED [PomBase:mah] synonym: "abnormal microtubule organization" RELATED [PomBase:mah] synonym: "disorganized microtubule cytoskeleton" RELATED [PomBase:vw] synonym: "microtubule cytoskeleton defects" EXACT [PomBase:mah] synonym: "microtubule organization defects" RELATED [PomBase:mah] is_a: FYPO:0000297 ! microtubule cytoskeleton organization phenotype is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000055 name: long microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal." [PomBase:mah] synonym: "elongated microtubules" EXACT [PomBase:mah] synonym: "long microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defects, long microtubules" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000056 name: mitochondria fused def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitochondria have fused into fewer and larger structures than normal, or failed to undergo fission." [PomBase:vw] synonym: "fused mitochondria" EXACT [PomBase:mah] synonym: "mitochondria fused during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondria fused during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000057 name: mitochondrial nucleoid enlarged def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitochondrial nucleoid is larger than normal." [PomBase:mah] synonym: "mitochondrial nucleoid enlarged during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial nucleoid enlarged during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000058 name: mitochondrial nucleoids present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer mitochondrial nucleoids than normal." [PomBase:mah] synonym: "decreased number of mitochondrial nucleoids" EXACT [PomBase:mah] synonym: "fewer mitochondrial nucleoids present" EXACT [PomBase:mah] synonym: "mitochondrial nucleoid decreased number" EXACT [PomBase:mah] synonym: "mitochondrial nucleoids present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial nucleoids present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial nucleoids present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000059 name: abnormal mitotic cell cycle def: "A cellular process phenotype in which a cell does not proceed normally through a mitotic cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "mitotic cell cycle defects" EXACT [PomBase:mah] synonym: "mitotic cell cycle: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000011 ! abnormal cell cycle created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000060 name: mononucleate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single nucleus." [PomBase:mah] synonym: "mononucleate during vegetative growth" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0002731 ! mononucleate created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000061 name: multinucleate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus." [PomBase:mah] synonym: "multinucleate cells during vegetative growth" EXACT [PomBase:al] synonym: "multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiple nuclei during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0003341 ! multinucleate created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000062 name: abnormal nuclear morphology during vegetative growth alt_id: FYPO:0000259 def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the nucleus is abnormal." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "abnormal nuclear morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "deformed nucleus during vegetative growth" EXACT [PomBase:vw] synonym: "nuclear morphology defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002256 ! abnormal nuclear morphology relationship: output_of FYPO:0000810 ! abnormal nucleus organization created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000063 name: abnormal DNA recombination def: "A cellular process phenotype in which DNA recombination is abnormal. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents." [GO:0006310, PomBase:mah] synonym: "abnormal recombination" EXACT [PomBase:vw] synonym: "recombination defects" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000064 name: resistance to 2-deoxyglucose def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 2-deoxyglucose than normal." [PomBase:mah] synonym: "resistance to 2-deoxyglucose during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to 2-deoxyglucose during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to 2-DOG" EXACT [PomBase:mah] synonym: "resistant to 2-deoxy-D-glucose" EXACT [CHEBI:15866, PomBase:mah] synonym: "resistant to 2-DOG" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000065 name: resistance to 5-azacytidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-azacytidine than normal." [PomBase:mah] synonym: "resistance to 5-azacytidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to 5-azacytidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to 5-azacytidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000066 name: resistance to L-azetidine-2-carboxylic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-azetidine-2-carboxylic acid than normal." [PomBase:mah] synonym: "resistance to (S)-azetidine-2-carboxylic acid" EXACT [CHEBI:6198, PomBase:mah] synonym: "resistance to AZC" BROAD [PomBase:mah] synonym: "resistance to L-azetidine-2-carboxylic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to L-azetidine-2-carboxylic acid during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to L-azetidine-2-carboxylic acid" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000067 name: resistance to brefeldin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of brefeldin A than normal." [PomBase:mah] synonym: "resistance to BFA" EXACT [PomBase:mah] synonym: "resistance to brefeldin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to brefeldin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to Brefeldin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000068 name: resistance to K-252a def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of K-252a than normal." [PomBase:mah] synonym: "resistance to K-252a during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to K-252a during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to K-252a" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000069 name: resistance to thiabendazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of thiabendazole than normal." [PomBase:mah] synonym: "resistance to TBZ" EXACT [PomBase:mah] synonym: "resistance to thiabendazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to thiabendazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to TBZ" EXACT [CHEBI:45979, PomBase:mah] synonym: "resistant to thiabendazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000070 name: resistance to amphotericin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amphotericin B than normal." [PomBase:mah] synonym: "resistance to amphotericin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to amphotericin B during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to amphotericin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000071 name: resistance to aureobasidin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aureobasidin A than normal." [PomBase:mah] synonym: "resistance to AbA" EXACT [PMID:9472078] synonym: "resistance to aureobasidin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to aureobasidin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to aureobasidin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000072 name: resistance to benomyl def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of benomyl than normal." [PomBase:mah] synonym: "resistance to benomyl during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to benomyl during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate" EXACT [CHEBI:3015] synonym: "resistant to benomyl" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000073 name: resistance to caffeine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caffeine than normal." [PomBase:mah] synonym: "resistance to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to caffeine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000074 name: obsolete resistance to drug def: "OBSOLETE. An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of a drug than normal." [PomBase:mah] comment: This term was made obsolete because 'drug' is not defined clearly. Search for a specific term for resistance to the substance used in the assay. synonym: "drug resistance" EXACT [PomBase:mah] synonym: "drug resistant" EXACT [PomBase:mah] synonym: "resistance to drug during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to drugs" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000075 name: resistance to lovastatin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lovastatin than normal." [PomBase:mah] synonym: "resistance to lovastatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to lovastatin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to lovastatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000076 name: resistance to nystatin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nystatin than normal." [PomBase:mah] synonym: "resistance to nystatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to nystatin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to nystatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000077 name: resistance to rapamycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of rapamycin than normal." [PomBase:mah] synonym: "resistance to rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to rapamycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000078 name: abnormal cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration is abnormal." [PomBase:mah] synonym: "abnormal cellular respiration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal respiration" BROAD [PomBase:mah] synonym: "abnormal respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000079 name: sensitive to caspofungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caspofungin. Cells stop growing (and may die) at a concentration of caspofungin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to caspofungin" EXACT [PomBase:mah] synonym: "sensitive to caspofungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to caspofungin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to glucan synthase inhibitor" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000080 name: decreased cell population growth at low temperature alt_id: FYPO:0002175 def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal at a low temperature." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. For fission yeast, low temperature usually corresponds to below 25 degrees Celsius. synonym: "cold sensitive" RELATED [PomBase:mah] synonym: "cold sensitivity: increased" RELATED [SGD:phenotype_annotation] synonym: "decreased growth at low temperature" BROAD [PomBase:mah] synonym: "decreased vegetative cell population growth at low temperature" EXACT [PomBase:mah] synonym: "growth defect, slow growth at low temperatures" RELATED [PomBase:mah] synonym: "hypersensitive to cold" RELATED [PomBase:mah] synonym: "reduced growth at low temperature" RELATED [PomBase:mah] synonym: "sensitive to cold" RELATED [PomBase:mah] synonym: "sensitive to cold during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cold during vegetative growth" EXACT [PomBase:mah] synonym: "slow growth at low temperature" RELATED [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000081 name: sensitive to high osmolarity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to conditions of high osmolarity." [PomBase:mah] synonym: "decreased growth during cellular response to high osmolarity" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to high osmolarity" EXACT [PomBase:mah] synonym: "hyperosmotic stress resistance: decreased" RELATED [SGD:phenotype_annotation] synonym: "hypersensitive to high osmolarity" EXACT [PomBase:mah] synonym: "sensitive to high osmolarity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to high osmolarity during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to hyperosmotic conditions" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000082 name: decreased cell population growth at high temperature alt_id: FYPO:0000247 def: "A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle at high temperatures." [PomBase:mah] comment: For fission yeast, high temperature usually corresponds to above 32 degrees Celsius. Use this term if you have assayed growth of cells exposed to heat in culture. If you have assayed the response to heat at the subcellular or molecular level, consider annotating to 'abnormal cellular response to heat' (FYPO:0000212). synonym: "decreased cell population growth at high temperature during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased growth at high temperature" BROAD [PomBase:mah] synonym: "decreased vegetative cell population growth at high temperature" EXACT [PomBase:mah] synonym: "growth defect, slow growth at high temperatures" NARROW [PomBase:mah] synonym: "heat sensitive" RELATED [PomBase:mah] synonym: "heat sensitivity: increased" RELATED [SGD:phenotype_annotation] synonym: "hypersensitive to high temperature" RELATED [PomBase:mah] synonym: "reduced growth at high temperature" EXACT [PomBase:mah] synonym: "sensitive to heat" RELATED [PomBase:mah] synonym: "sensitive to high temperature" RELATED [PomBase:mah] synonym: "sensitive to high temperature during vegetative growth" RELATED [PomBase:mah] synonym: "slow growth at high temperature" NARROW [PomBase:mah] synonym: "temperature sensitive" RELATED [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000083 name: sensitive to enfumafungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to enfumafungin. Cells stop growing (and may die) at a concentration of enfumafungin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to enfumafungin" EXACT [PomBase:mah] synonym: "sensitive to enfumafungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to enfumafungin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to glucan synthase inhibitor" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000084 name: sensitive to 6-azauracil def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 6-azauracil. Cells stop growing (and may die) at a concentration of 6-azauracil that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 6-azauracil" EXACT [PomBase:mah] synonym: "sensitive to 6-azauracil during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 6-azauracil during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000085 name: sensitive to camptothecin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to camptothecin. Cells stop growing (and may die) at a concentration of camptothecin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to camptothecin" EXACT [PomBase:mah] synonym: "sensitive to camptothecin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to CPT" EXACT [CHEBI:27656, PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000086 name: sensitive to tacrolimus def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tacrolimus. Cells stop growing (and may die) at a concentration of tacrolimus that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tacrolimus" EXACT [PomBase:mah] synonym: "sensitive to FK506" EXACT [CHEBI:61057, PomBase:mah] synonym: "sensitive to tacrolimus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tacrolimus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000087 name: sensitive to hydrogen peroxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrogen peroxide. Cells stop growing (and may die) at a concentration of hydrogen peroxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hydrogen peroxide" EXACT [PomBase:mah] synonym: "sensitive to H2O2" EXACT [PomBase:mah] synonym: "sensitive to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents is_a: FYPO:0000726 ! sensitive to oxidative stress created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000088 name: sensitive to hydroxyurea def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydroxyurea. Cells stop growing (and may die) at a concentration of hydroxyurea that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hydroxyurea" EXACT [PomBase:mah] synonym: "sensitive to HU" EXACT [PomBase:mah] synonym: "sensitive to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000089 name: sensitive to methyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methyl methanesulfonate. Cells stop growing (and may die) at a concentration of methyl methanesulfonate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "sensitive to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "sensitive to MMS" EXACT [CHEBI:25255, PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000090 name: sensitive to N-ethylmaleimide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-ethylmaleimide. Cells stop growing (and may die) at a concentration of N-ethylmaleimide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to N-ethylmaleimide" EXACT [PomBase:mah] synonym: "sensitive to N-ethylmaleimide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to N-ethylmaleimide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to NEM" EXACT [CHEBI:44485, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000091 name: sensitive to thiabendazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to thiabendazole. Cells stop growing (and may die) at a concentration of thiabendazole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to thiabendazole" EXACT [PomBase:mah] synonym: "sensitive to TBZ" EXACT [CHEBI:45979, PomBase:mah] synonym: "sensitive to thiabendazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to thiabendazole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000092 name: sensitive to amiodarone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amiodarone. Cells stop growing (and may die) at a concentration of amiodarone that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to amiodarone" EXACT [PomBase:mah] synonym: "sensitive to amiodarone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to amiodarone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000093 name: sensitive to arsenic def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to an arsenic-containing substance. Cells stop growing (and may die) at a concentration of arsenic that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to arsenic" EXACT [PomBase:mah] synonym: "sensitive to arsenic during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to arsenic during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to arsenic molecular entity" EXACT [CHEBI:22632] synonym: "sensitive to arsenic-containing substance" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000094 name: sensitive to benomyl def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to benomyl. Cells stop growing (and may die) at a concentration of benomyl that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to benomyl" EXACT [PomBase:mah] synonym: "sensitive to benomyl during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to benomyl during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate" EXACT [CHEBI:3015] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000095 name: sensitive to bleomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bleomycin. Cells stop growing (and may die) at a concentration of bleomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bleomycin" EXACT [PomBase:mah] synonym: "sensitive to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to bleomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000096 name: sensitive to cadmium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cadmium. Cells stop growing (and may die) at a concentration of cadmium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cadmium" EXACT [PomBase:mah] synonym: "sensitive to cadmium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cadmium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to cadmium ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000097 name: sensitive to caffeine during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caffeine. Cells stop growing (and may die) at a concentration of caffeine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to caffeine during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000098 name: sensitive to calcium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium. Cells stop growing (and may die) at a concentration of calcium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to calcium" EXACT [PomBase:mah] synonym: "sensitive to calcium chloride" NARROW [PomBase:mah] synonym: "sensitive to calcium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to calcium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to calcium ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000099 name: sensitive to canavanine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to canavanine. Cells stop growing (and may die) at a concentration of canavanine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to canavanine" EXACT [PomBase:mah] synonym: "sensitive to canavanine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to canavanine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000100 name: sensitive to chloramphenicol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chloramphenicol. Cells stop growing (and may die) at a concentration of chloramphenicol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to chloramphenicol" EXACT [PomBase:mah] synonym: "sensitive to chloramphenicol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to chloramphenicol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000101 name: sensitive to chlorpropham def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chlorpropham. Cells stop growing (and may die) at a concentration of chlorpropham that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to chlorpropham" EXACT [PomBase:mah] synonym: "sensitive to chlorpropham during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to chlorpropham during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to isopropyl N-3-chlorophenyl carbamate" EXACT [PomBase:mah] synonym: "sensitive to spindle poison" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000102 name: sensitive to cisplatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cisplatin. Cells stop growing (and may die) at a concentration of cisplatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cisplatin" EXACT [PomBase:mah] synonym: "sensitive to cis-DDP" EXACT [CHEBI:27899] synonym: "sensitive to cisplatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cisplatin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DDP" BROAD [CHEBI:27899, PomBase:al] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000103 name: sensitive to copper def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to copper ions. Cells stop growing (and may die) at a concentration of copper ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to copper" EXACT [PomBase:mah] synonym: "sensitive to copper during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to copper during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to copper ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000104 name: sensitive to cycloheximide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cycloheximide. Cells stop growing (and may die) at a concentration of cycloheximide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cycloheximide" EXACT [PomBase:mah] synonym: "sensitive to cycloheximide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cycloheximide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000105 name: sensitive to cyclosporin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cyclosporin A. Cells stop growing (and may die) at a concentration of cyclosporin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cyclosporin A" EXACT [PomBase:mah] synonym: "sensitive to cyclosporin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cyclosporin A during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to cyclosporine" EXACT [CHEBI:4031, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000106 name: sensitive to hygromycin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hygromycin B. Cells stop growing (and may die) at a concentration of hygromycin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hygromycin B" EXACT [PomBase:mah] synonym: "sensitive to hygromycin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to hygromycin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000107 name: sensitive to latrunculin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to latrunculin A. Cells stop growing (and may die) at a concentration of latrunculin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to latrunculin A" EXACT [PomBase:mah] synonym: "sensitive to LAT-A" EXACT [PomBase:vw] synonym: "sensitive to LatA" EXACT [PomBase:mah] synonym: "sensitive to latrunculin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to latrunculin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000108 name: sensitive to menadione def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to menadione. Cells stop growing (and may die) at a concentration of menadione that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to menadione" EXACT [PomBase:mah] synonym: "sensitive to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to vitamin K3" RELATED [PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000109 name: sensitive to papulacandin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to papulacandin B. Cells stop growing (and may die) at a concentration of papulacandin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to papulacandin B" EXACT [PomBase:mah] synonym: "sensitive to papulacandin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to papulacandin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000110 name: sensitive to pravastatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pravastatin. Cells stop growing (and may die) at a concentration of pravastatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to pravastatin" EXACT [PomBase:mah] synonym: "sensitive to pravastatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to pravastatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000111 name: sensitive to rapamycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rapamycin. Cells stop growing (and may die) at a concentration of rapamycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to rapamycin" EXACT [PomBase:mah] synonym: "sensitive to rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to rapamycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000112 name: sensitive to sorbitol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sorbitol. Cells stop growing (and may die) at a concentration of sorbitol that allows wild type cells to grow." [PomBase:mah] comment: Consider also annotating to 'sensitive to non-ionic osmotic stress' (FYPO:0002811) because sorbitol is often used to cause osmotic stress. synonym: "hypersensitive to sorbitol" EXACT [PomBase:mah] synonym: "sensitive to glucitol" EXACT [CHEBI:30911, PomBase:mah] synonym: "sensitive to sorbitol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sorbitol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000113 name: sensitive to staurosporine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to staurosporine. Cells stop growing (and may die) at a concentration of staurosporine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to staurosporine" EXACT [PomBase:mah] synonym: "sensitive to staurosporine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to staurosporine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000114 name: cellular process phenotype def: "A phenotype that affects a cellular process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cellular process phenotype" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-04-12T12:00:38Z [Term] id: FYPO:0000115 name: sensitive to valproic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to valproic acid. Cells stop growing (and may die) at a concentration of valproic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to valproic acid" EXACT [PomBase:mah] synonym: "sensitive to valproic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to valproic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000116 name: sensitive to zinc def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zinc ions. Cells stop growing (and may die) at a concentration of zinc ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to zinc" EXACT [PomBase:mah] synonym: "sensitive to zinc during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to zinc during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to zinc ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000117 name: abnormal septum assembly alt_id: FYPO:0000170 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly is abnormal." [PomBase:mah] synonym: "abnormal division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "abnormal division septum formation involved in mitotic cytokinesis" EXACT [PomBase:mah] synonym: "abnormal septation" BROAD [GO:0000917, PomBase:mah] synonym: "abnormal septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "septation defects" BROAD [PomBase:mah] synonym: "septum formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000118 name: multiseptate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle characterized by the presence of more than one septum in a cell." [PomBase:mah] synonym: "multiseptate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiseptate during vegetative growth" EXACT [PomBase:mah] synonym: "septation defects, multiple septa during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002342 ! septated vegetative cell is_a: FYPO:0004295 ! multiseptate cell relationship: output_of FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000119 name: abnormal spindle assembly alt_id: FYPO:0000285 def: "A cellular process phenotype in which spindle assembly is abnormal. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle." [GO:0051225, PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization is_a: FYPO:0000336 ! abnormal cellular component assembly created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000120 name: abnormal spindle alt_id: FYPO:0000367 def: "A physical cellular phenotype in which the presence, distribution, or morphology of the mitotic or meiotic spindle is abnormal." [PomBase:mah] synonym: "spindle defects" EXACT [PomBase:mah] is_a: FYPO:0002399 ! abnormal microtubule cytoskeleton created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000121 name: abnormal sporulation def: "A cellular process phenotype in which ascospore formation is abnormal." [PomBase:mah] synonym: "abnormal ascospore formation" EXACT [PomBase:mah] synonym: "sporulation defects" EXACT [PomBase:mah] synonym: "sporulation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000122 name: abnormal telomere maintenance during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal." [GO:0000723, PomBase:mah] synonym: "abnormal telomere maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "telomere maintenance defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0007415 ! abnormal telomere maintenance created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000123 name: large vacuoles during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are larger than normal." [PomBase:mah] synonym: "enlarged vacuoles during vegetative growth" EXACT [PomBase:mah] synonym: "large vacuoles during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vacuole organization defects, large vacuoles" EXACT [PomBase:mah] is_a: FYPO:0000368 ! abnormal vacuolar morphology during vegetative growth is_a: FYPO:0007821 ! large vacuoles created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000124 name: viable cell def: "A viability phenotype in which a cell is able to survive under the specified conditions." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000004 ! cell viability created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000125 name: resistance to amiloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amiloride than normal." [PomBase:mah] synonym: "resistance to amiloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to amiloride during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to amiloride" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000126 name: increased resistance to chemical during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to a chemical stimulus. Resistance to a chemical is usually measured by determining the maximum concentration of the chemical at which a population of cells grow and divide, and cells are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type cells to grow." [PomBase:mah] synonym: "increased resistance to chemical during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to chemicals: increased during vegetative growth" EXACT [PomBase:mah, SGD:phenotype_annotation] synonym: "resistant to chemical during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth is_a: FYPO:0002682 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000127 name: increased sensitivity to chemical during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased resistance to a chemical stimulus. Resistance to a chemical is measured by determining the maximum concentration of the chemical at which a population of cells grow and divide. Typically, cells are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type cells to grow." [PomBase:mah] synonym: "increased sensitivity to chemical during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to chemicals: decreased during vegetative growth" EXACT [PomBase:mah, SGD:phenotype_annotation] is_a: FYPO:0001356 ! abnormal vegetative cell population growth is_a: FYPO:0002683 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000128 name: auxotrophy def: "A phenotype in which a cell requires a particular organic compound, which is not required by a wild-type cell for its growth. Auxotrophy usually results from a cell's inability to synthesize the compound." [PATO:0000422, PomBase:mah] synonym: "auxotrophic growth" EXACT [PomBase:vw] synonym: "auxotrophy during mitotic cell cycle" RELATED [PomBase:mah] synonym: "auxotrophy during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000129 name: spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is formed in the shape of a sphere." [PomBase:mah] synonym: "orb during vegetative growth" EXACT [PomBase:jh, PomBase:vw] synonym: "spherical cells during vegetative growth" EXACT [PomBase:mah] synonym: "spherical vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0001956 ! spherical cell created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000130 name: short spindle def: "A spindle phenotype in which the spindle is shorter than normal." [PomBase:mah] synonym: "decreased spindle length" EXACT [PomBase:mah] synonym: "short spindles" EXACT [PomBase:mah] synonym: "spindle defects, short spindles" EXACT [PomBase:mah] is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000131 name: abnormal mitotic spindle elongation def: "A spindle phenotype in which mitotic spindle elongation, i.e. the process of lengthening the distance between poles of the mitotic spindle, is abnormal." [GO:0000022, PomBase:mah] synonym: "abnormal mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spindle elongation during mitosis" EXACT [PomBase:mah] synonym: "abnormal spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle elongation defects" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process relationship: has_output FYPO:0001574 ! abnormal bipolar mitotic spindle relationship: part_of FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000132 name: abnormal septum disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum disassembly is abnormal; may result in the formation of chains of attached cells." [PomBase:mah] synonym: "abnormal septum disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septum disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "chained cells" RELATED [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000133 name: elongated multinucleate vegetative cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus, is longer than normal, and has a greater length:diameter ratio than normal." [PomBase:mah] synonym: "elongated multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long multinucleate vegetative cell" EXACT [PomBase:vw] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0003342 ! elongated multinucleate cell relationship: has_part FYPO:0000061 ! multinucleate vegetative cell relationship: has_part FYPO:0001122 ! elongated vegetative cell relationship: output_of FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000134 name: branched, elongated, multiseptate cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell forms one or more branches near a septum, is elongated, and has more than one septum." [PomBase:mah] synonym: "branched, elongated, multiseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched, elongated, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, long, multiseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0004594 ! branched, elongated, septated cell created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000135 name: abnormal plasma membrane sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the plasma membrane is abnormal." [GO:0097036, PomBase:mah] synonym: "abnormal plasma membrane sterol distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal plasma membrane sterol distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of plasma membrane sterol distribution" EXACT [GO:0097036, PomBase:mah] synonym: "localization defects, sterol distribution defects" EXACT [PomBase:mah] is_a: FYPO:0007677 ! abnormal sterol distribution created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000136 name: cellular physical quality phenotype def: "A phenotype that affects any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cellular physical object quality phenotype" EXACT [PATO:0001241] synonym: "fission yeast cellular physical object quality phenotype" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2011-04-12T12:01:21Z [Term] id: FYPO:0000137 name: mitotic cell cycle checkpoint phenotype def: "A cell phenotype that affects any mitotic cell cycle checkpoint." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast mitotic cell cycle checkpoint phenotype" EXACT [PomBase:mah] is_a: FYPO:0000631 ! cell cycle phenotype is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2011-04-12T12:55:38Z [Term] id: FYPO:0000138 name: localization phenotype def: "A cell phenotype that affects the localization of a structure or substance in a cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast localization phenotype" EXACT [PomBase:mah] synonym: "localisation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T02:16:04Z [Term] id: FYPO:0000139 name: cell population growth phenotype def: "A cell phenotype that affects the rate or extent of cell population growth. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cell population growth phenotype" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2011-04-12T02:22:51Z [Term] id: FYPO:0000140 name: cellular metabolism phenotype def: "A cellular process phenotype that affects metabolism in the cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cellular metabolism phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T02:23:26Z [Term] id: FYPO:0000141 name: abnormal mitotic sister chromatid segregation alt_id: FYPO:0001359 def: "A cellular process phenotype in which mitotic sister chromatid segregation is abnormal. Mitotic sister chromatid segregation is the entire process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle." [GO:0000070, PomBase:mah] synonym: "abnormal chromosome segregation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid segregation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sister chromatid segregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "centromere function defective during vegetative growth" RELATED [PomBase:mah] synonym: "chromosome segregation defects during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome segregation defects, mitotic" EXACT [PomBase:mah] synonym: "mitotic chromosome missegregation" RELATED [PomBase:vw] synonym: "mitotic sister chromatid missegregation" RELATED [PomBase:vw] is_a: FYPO:0000029 ! abnormal chromosome segregation is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process relationship: part_of FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2011-04-12T05:41:15Z [Term] id: FYPO:0000142 name: gene expression phenotype def: "A cellular process phenotype that affects gene expression. Gene expression includes transcription, RNA processing, and, for protein-coding genes, translation and protein maturation." [GO:0010467, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast gene expression phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T05:46:51Z [Term] id: FYPO:0000143 name: transcription regulation phenotype def: "A gene expression phenotype that affects the regulation of DNA-dependent transcription." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast transcription regulation phenotype" EXACT [PomBase:mah] synonym: "gene-specific transcription regulation phenotype" RELATED [GO:0006355, PomBase:mah] synonym: "transcriptional control phenotype" BROAD [GO:0006355, PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype created_by: midori creation_date: 2011-04-12T05:47:38Z [Term] id: FYPO:0000144 name: abnormal chromatin silencing def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "abnormal chromatin silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000574 ! abnormal gene silencing is_a: FYPO:0000624 ! abnormal negative regulation of transcription during vegetative growth created_by: midori creation_date: 2011-04-12T05:48:37Z [Term] id: FYPO:0000145 name: regulation phenotype def: "A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast regulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T06:00:44Z [Term] id: FYPO:0000146 name: abnormal chromatin silencing at centromere def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal in centromeric regions. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "abnormal chromatin silencing at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal heterochromatin silencing at centromere" RELATED [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000147 name: abnormal NETO def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is abnormal." [PomBase:mah] synonym: "abnormal cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "abnormal NETO during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal new end take-off" EXACT [PomBase:mah] synonym: "abnormal switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] is_a: FYPO:0000191 ! abnormal regulation of establishment or maintenance of cell polarity created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000148 name: abnormal regulation of mitotic cell cycle def: "A regulation phenotype in which regulation of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000059 ! abnormal mitotic cell cycle is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000149 name: transport phenotype def: "A cell process phenotype that affects a transport process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast transport phenotype" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype created_by: midori creation_date: 2011-04-14T05:43:20Z [Term] id: FYPO:0000150 name: abnormal colony morphology def: "A cell population phenotype in which the morphology, i.e. the size, shape, or structure, of a colony growing on a solid surface is abnormal." [PomBase:mah] synonym: "colony shape: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000151 name: abnormal meiotic chromosome segregation def: "A cellular process phenotype in which meiotic chromosome segregation is abnormal. Meiotic chromosome segregation is the entire process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GO:0045132, PomBase:mah] synonym: "meiotic chromosome missegregation" RELATED [PomBase:vw] is_a: FYPO:0000029 ! abnormal chromosome segregation is_a: FYPO:0002739 ! abnormal meiotic cell cycle process relationship: part_of FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000152 name: abnormal cellular response to nitrogen starvation def: "A stress response phenotype in which the response to nitrogen starvation is abnormal." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. Use this term if you have assayed the response to nitrogen starvation at the subcellular or molecular level. If you have assayed growth of cells exposed to nitrogen starvation in culture, use 'sensitive to nitrogen starvation' (FYPO:0002124). synonym: "abnormal cellular response to nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal cellular response to nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000713 ! abnormal cellular response to starvation created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000153 name: obsolete clumped colony morphology def: "OBSOLETE. A colony morphology phenotype in which cells form clumps. Clumping may result from incomplete hydrolysis of septum edging material, causing cells to remain attached via remnants of the septum edging, or from cell-cell adhesion between cells that do not have a shared origin." [PMID:15194814, PomBase:ch, PomBase:mah] comment: This term was made obsolete because it was added to map an out-of-date controlled vocabulary term, and unhelpfully groups two fairly unrelated phenomena. is_obsolete: true created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000154 name: abnormal negative regulation of G0 to G1 transition def: "A regulation phenotype in which negative regulation of the G0 to G1 transition is abnormal." [PomBase:mah] synonym: "abnormal maintenance of cell cycle quiescence" EXACT [PomBase:mah] synonym: "abnormal maintenance of cell quiescence" EXACT [PomBase:mah] synonym: "abnormal maintenance of G0 arrest" EXACT [PomBase:mah] synonym: "abnormal maintenance of G0 phase" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000155 name: increased flocculation alt_id: FYPO:0000462 def: "A cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells." [GO:0000128, PomBase:mah] comment: Note that all normally occurring flocculation in S. pombe is galactose-specific, but other types of flocculation may abnormally occur. synonym: "flocculating cells" EXACT [PomBase:mah] synonym: "flocculation: increased" RELATED [SGD:phenotype_annotation] synonym: "increased cell-cell adhesion" BROAD [PomBase:mah, PomBase:vw] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0005447 ! abnormal biological process created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000156 name: abnormal chromatin silencing at silent mating-type cassette def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abnormal chromatin silencing at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000157 name: abnormal response to DNA damage stimulus during vegetative growth def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to DNA damage is abnormal." [PomBase:mah] comment: Use this term if you have assayed the response to DNA damage at the subcellular or molecular level. If you have assayed growth of cells exposed to DNA damage in culture, use 'sensitive to DNA damage' (FYPO:0000265). Also consider specific phenotype terms for sensitivity to substances or other stimuli that can damage DNA, e.g. 'sensitive to DNA damaging agents' (FYPO:0000266), 'sensitive to methyl methanesulfonate' (FYPO:0000089), 'sensitive to UV' (FYPO:0000268), etc. synonym: "abnormal response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal response to DNA damage stimulus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000158 name: DNA content increased during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of DNA in a cell is greater than normal." [PomBase:mah] synonym: "DNA content increased during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA content during vegetative growth" EXACT [PomBase:mah] synonym: "increased DNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0002729 ! DNA content increased is_a: FYPO:0004321 ! altered DNA level during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000159 name: abnormal chromosome condensation alt_id: FYPO:0000028 def: "A cellular process phenotype in which chromosome condensation is abnormal. Chromosome condensation is the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division." [GO:0030261, PomBase:mah] synonym: "chromosome condensation defects" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation created_by: midori creation_date: 2011-04-14T10:44:38Z [Term] id: FYPO:0000160 name: fragmented DNA def: "A cell phenotype in which DNA is broken into small fragments." [PomBase:mah] comment: Use 'fragmented DNA' (FYPO:0000160) or one of its descendants if DNA was detected using a method that can resolve molecule sizes (e.g. gel electrophoresis) or detect DNA ends (e.g. TUNEL assay). Otherwise, consider using 'fragmented nucleus' (FYPO:0001919) or one of its descendants. synonym: "DNA fragmentation" EXACT [PomBase:mah] synonym: "fragmented nucleus" RELATED [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000161 name: abnormal actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is abnormal. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins." [GO:1903475, PomBase:mah] synonym: "abnormal actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:mah] synonym: "abnormal contractile ring assembly" EXACT [PomBase:mah] synonym: "abnormal cytokinesis, actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "abnormal cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "abnormal cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "abnormal cytokinetic ring formation" RELATED [PomBase:vw] synonym: "abnormal mitotic contractile ring assembly" EXACT [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000162 name: abnormal cellular response to stress def: "A cellular response phenotype in which a cellular response to stress is abnormal." [PomBase:mah] comment: Use a descendant of this term if you have assayed the response to a stress at the subcellular or molecular level. If you have assayed growth of cells exposed to the stress in culture, use a descendant of 'sensitive to stress' (FYPO:0002549) or 'resistance to stress' (FYPO:0002046). is_a: FYPO:0000298 ! cellular response phenotype created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000163 name: abnormal macroautophagy alt_id: FYPO:0000379 def: "A cellular process phenotype in which macroautophagy is abnormal. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm." [GO:0016236, PomBase:mah] synonym: "abnormal autophagy" BROAD [PomBase:mah] synonym: "autophagy: abnormal" BROAD [SGD:phenotype_annotation] is_a: FYPO:0008082 ! abnormal autophagy created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000164 name: abnormal cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormal. Cell separation is the process of physically separating progeny cells after cytokinesis is complete, and involves enzymatic digestion of septum components." [GO:0000920, PomBase:mah] synonym: "abnormal cell separation after cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cytokinetic cell separation" EXACT [GO:0000920, PomBase:mah] synonym: "abnormal septum digestion after cytokinesis" EXACT [GO:0000920] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000165 name: abnormal regulation of mating def: "A regulation phenotype in which regulation of conjugation is abnormal." [PomBase:mah] synonym: "abnormal regulation of conjugation with cellular fusion" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000166 name: abnormal regulation of G2/M transition of mitotic cell cycle def: "A regulation phenotype in which negative regulation of the G2 to M transition of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0000399 ! abnormal mitotic G2/M phase transition created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000167 name: increased DNA recombination at mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of DNA recombination at replication fork barriers is increased." [PomBase:mah] synonym: "DNA recombination defect, at mitotic DNA replication fork barriers, elevated" EXACT [PomBase:mah] synonym: "increased DNA recombination at mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA recombination at mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] synonym: "increased recombination at mitotic DNA replication fork barriers" EXACT [PomBase:vw] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000168 name: abnormal mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the spindle assembly checkpoint of a mitotic cell cycle is abnormal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0007094, PomBase:mah] synonym: "abnormal mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle assembly checkpoint activation" RELATED [PomBase:mah] is_a: FYPO:0000200 ! abnormal regulation of mitotic metaphase/anaphase transition is_a: FYPO:0001704 ! abnormal mitotic cell cycle checkpoint created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000169 name: abnormal chromatin silencing at subtelomere def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at subtelomeric regions is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abnormal chromatin silencing at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at telomere" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at telomere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000171 name: abnormal late endosome to vacuole transport def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which late endosome to vacuole transport is abnormal." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) from the late endosome to the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "abnormal late endosome to vacuole protein transport" NARROW [PomBase:mah] synonym: "abnormal late endosome to vacuole transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal late endosome to vacuole transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport during vegetative growth is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000172 name: abnormal meiotic telomere clustering def: "A meiosis phenotype in which meiotic telomere clustering is abnormal. Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body." [GO:0045141, PomBase:mah] synonym: "abnormal bouquet formation" EXACT [PomBase:vw] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0006393 ! localization phenotype during meiotic cell cycle created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000173 name: abnormal mitotic cell cycle DNA replication checkpoint alt_id: FYPO:0000823 def: "A cell cycle checkpoint phenotype in which the DNA replication checkpoint in a mitotic cell cycle is abnormal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal DNA replication checkpoint" BROAD [PomBase:mah] synonym: "abnormal mitotic cell cycle DNA replication checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0000166 ! abnormal regulation of G2/M transition of mitotic cell cycle is_a: FYPO:0000643 ! abnormal mitotic DNA integrity checkpoint created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000174 name: abnormal cell wall biogenesis def: "A cellular process phenotype in which cell wall biogenesis is abnormal." [PomBase:mah] synonym: "abnormal fungal-type cell wall biogenesis" EXACT [GO:0009272, PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process relationship: has_output FYPO:0002946 ! abnormal cell wall created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000175 name: abnormal ascospore wall assembly def: "A sporulation phenotype in which ascospore wall assembly is abnormal." [PomBase:mah] synonym: "abnormal ascospore wall organization" RELATED [PomBase:mah] synonym: "abnormal spore wall formation" RELATED [PomBase:mah] synonym: "spore wall formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0002739 ! abnormal meiotic cell cycle process relationship: part_of FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000176 name: abnormal DNA replication initiation def: "A cellular process phenotype in which the initiation of DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication initiation" EXACT [PomBase:mah] is_a: FYPO:0000217 ! abnormal DNA replication created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000177 name: abnormal mitotic spindle assembly alt_id: FYPO:0001349 def: "A cellular process phenotype in which assembly of the mitotic spindle is abnormal. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle." [PomBase:mah] synonym: "abnormal bipolar spindle formation" EXACT [GO:0051225] synonym: "abnormal mitotic spindle assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spindle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000119 ! abnormal spindle assembly is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process relationship: has_output FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000178 name: abnormal regulation of cytokinesis def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of cytokinesis is abnormal." [PomBase:mah] synonym: "abnormal regulation of cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000179 name: abnormal protein targeting via MVB pathway def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole via the multivesicular sorting pathway, leading to ubiquitin-dependent protein degradation, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway" EXACT [PomBase:mah] synonym: "abnormal protein targeting via multivesicular body sorting pathway" EXACT [PomBase:mah] synonym: "abnormal protein targeting via MVB pathway during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein targeting via the multivesicular body sorting pathway during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000171 ! abnormal late endosome to vacuole transport is_a: FYPO:0000676 ! abnormal protein targeting to vacuole created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000180 name: abnormal cellular response to oxidative stress def: "A stress response phenotype in which a cellular response to oxidative stress is abnormal." [PomBase:mah] synonym: "abnormal oxidative stress response" EXACT [PomBase:vw] is_a: FYPO:0000162 ! abnormal cellular response to stress created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000181 name: abolished crossover def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which reciprocal DNA recombination does not occur." [PomBase:mah] synonym: "abolished crossover during mitotic cell cycle" RELATED [PomBase:mah] synonym: "crossover abolished" EXACT [PomBase:mah] synonym: "crossover abolished during vegetative growth" EXACT [PomBase:mah] synonym: "DNA recombination defects, crossover, abolished" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000182 name: abnormal cell wall organization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GO:0031505, PomBase:mah] synonym: "abnormal cell wall organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell wall organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal fungal-type cell wall organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0004805 ! abnormal cell wall organization created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000183 name: abnormal poly(A)+ mRNA export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is abnormal." [PomBase:mah] synonym: "abnormal poly(A)+ mRNA export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal poly(A)+ mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal polyadenylated mRNA export from nucleus" EXACT [PomBase:mah] is_a: FYPO:0000204 ! abnormal mRNA export from nucleus created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000184 name: abnormal regulation of pseudohyphal growth def: "A regulation phenotype in which regulation of pseudohyphal growth is abnormal." [PomBase:mah] synonym: "abnormal regulation of filamentous growth" BROAD [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000185 name: decreased gene conversion during vegetative growth def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased gene conversion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "DNA recombination defects, gene conversion, reduced" EXACT [PomBase:mah] synonym: "reduced gene conversion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000186 name: abnormal cell division during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell division is abnormal." [PomBase:mah] synonym: "abnormal cell division" BROAD [PomBase:mah] synonym: "abnormal cell division during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000187 name: abnormal heterochromatin assembly by small RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is abnormal. Small RNA-mediated heterochromatin assembly results in transcriptional silencing." [PomBase:mah] synonym: "abnormal chromatin silencing by small RNA" EXACT [PomBase:mah] synonym: "abnormal heterochromatin assembly by small RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal heterochromatin assembly by small RNA during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNAi-mediated chromatin silencing" EXACT [PomBase:al] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000188 name: abnormal DNA repair during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA repair is abnormal." [PomBase:mah] synonym: "abnormal DNA repair during mitotic cell cycle" RELATED [] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0006567 ! abnormal DNA repair created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000189 name: abnormal mRNA splicing, via spliceosome def: "A cellular process phenotype in which mRNA splicing via the spliceosome is abnormal." [PomBase:mah] synonym: "abnormal mRNA splicing, via spliceosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nuclear mRNA splicing, via spliceosome" EXACT [PomBase:mah] is_a: FYPO:0002915 ! abnormal RNA splicing, via spliceosome created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000190 name: abnormal actin cortical patch localization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch location during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal actin patch localization during vegetative growth" EXACT [PomBase:mah, PomBase:vw] synonym: "abnormal F-actin patch localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000191 name: abnormal regulation of establishment or maintenance of cell polarity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] synonym: "abnormal regulation of establishment or maintenance of cell polarity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of establishment or maintenance of cell polarity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000192 name: obsolete abnormal regulation of S phase of mitotic cell cycle def: "OBSOLETE. A regulation phenotype in which regulation of progression through S phase of the mitotic cell cycle is abnormal." [PomBase:mah] comment: This term was made obsolete because it was based on a GO term (GO:0007090) that has itself been made obsolete. is_obsolete: true created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000193 name: abnormal cellular response to osmotic stress def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which a cellular response to osmotic stress is abnormal." [PomBase:mah] comment: Use this term if you have assayed the response to osmotic stress at the subcellular or molecular level. If you have assayed growth of cells exposed to osmotic stress in culture, use 'sensitive to osmotic stress' (FYPO:0000270) or 'resistance to osmotic stress' (FYPO:0000851). synonym: "abnormal cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000194 name: abnormal cellular response to hydrogen peroxide def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which a cellular response to hydrogen peroxide is abnormal." [PomBase:mah] synonym: "abnormal cellular response to H2O2" EXACT [PomBase:mah] synonym: "abnormal cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001340 ! abnormal cellular response to oxidative stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000196 name: abnormal prospore formation def: "A sporulation phenotype in which prospore formation is abnormal. In prospore formation, each haploid nucleus becomes encapsulated by a double membrane." [PomBase:mah] synonym: "abnormal ascospore-type prospore assembly" EXACT [GO:0031321] synonym: "abnormal ascospore-type prospore formation" EXACT [PomBase:mah] synonym: "abnormal forespore formation" EXACT [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0002739 ! abnormal meiotic cell cycle process relationship: part_of FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000197 name: abnormal horsetail movement def: "A cellular process phenotype in which horsetail movement is abnormal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] comment: Consider also annotating to 'abnormal horsetail nucleus morphology' (FYPO:0002890). synonym: "abnormal dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989, PomBase:mah] synonym: "abnormal horsetail nuclear movement" EXACT [GO:0030989, PomBase:mah] is_a: FYPO:0001720 ! abnormal transport is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000198 name: abnormal establishment or maintenance of actin cytoskeleton polarity during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of actin cytoskeleton polarity is abnormal." [PomBase:mah] synonym: "abnormal actin cytoskeleton polarisation during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal actin cytoskeleton polarization during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal establishment or maintenance of actin cytoskeleton polarity during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000026 ! abnormal vegetative cell polarity is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000199 name: increased long tract gene conversion def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of long tract gene conversion is increased." [PomBase:mah] synonym: "DNA recombination defects, long tract gene conversion, increased" EXACT [PomBase:mah] synonym: "increased long tract gene conversion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased long tract gene conversion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000200 name: abnormal regulation of mitotic metaphase/anaphase transition def: "A regulation phenotype in which regulation of the mitotic metaphase to anaphase transition is abnormal." [PomBase:mah] synonym: "abnormal regulation of metaphase/anaphase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0006477 ! abnormal mitotic metaphase/anaphase transition created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000201 name: abnormal histone deacetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone deacetylation is abnormal." [PomBase:mah] synonym: "abnormal histone deacetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000202 name: abnormal regulation of cytokinetic cell separation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of cytokinetic cell separation is abnormal." [PomBase:mah] synonym: "abnormal regulation of cell separation after cytokinesis" EXACT [GO:0010590, PomBase:mah] synonym: "abnormal regulation of cell separation following cytokinesis" EXACT [GO:0010590, PomBase:mah] synonym: "abnormal regulation of cytokinetic cell separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of cytokinetic cell separation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic cytokinetic cell separation" EXACT [GO:0010590, PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000203 name: abnormal ergosterol biosynthetic process def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which ergosterol biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal ergosterol biosynthesis" EXACT [PomBase:mah] synonym: "abnormal ergosterol biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ergosterol biosynthetic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000204 name: abnormal mRNA export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of mRNA from the nucleus is abnormal." [PomBase:mah] synonym: "abnormal mRNA export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000360 ! abnormal RNA localization during vegetative growth is_a: FYPO:0000506 ! abnormal nuclear export is_a: FYPO:0004852 ! RNA transport phenotype is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000206 name: abnormal chromatin silencing at rDNA def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeats is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abnormal chromatin silencing at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at ribosomal DNA" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000207 name: abnormal cellular response to caffeine def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to caffeine is abnormal." [PomBase:mah] synonym: "abnormal cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000208 name: abnormal cellular response to cadmium ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to cadmium ions is abnormal." [PomBase:mah] synonym: "abnormal cellular response to cadmium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to cadmium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000209 name: abnormal attachment of spindle microtubules to kinetochore during meiosis I def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division is abnormal." [PomBase:mah] comment: Abnormal kinetochore attachment may cause separation of sister chromatids during the first meiotic nuclear division, leading to equational segregation. If this occurs, also annotate to 'equational sister chromatid separation during meiosis I' (FYPO:0005634). synonym: "abnormal attachment of spindle microtubules to kinetochore during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to meiosis I kinetochore" EXACT [PomBase:vw] synonym: "abnormal kinetochore mono-orientation at meiosis I" EXACT [PomBase:vw] synonym: "abnormal kinetochore orientation at meiosis I" EXACT [PomBase:vw] synonym: "abnormal sister kinetochore mono-orientation" EXACT [GO:0051455] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000211 name: obsolete abnormal cellular response to drug def: "OBSOLETE. A chemical response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a chemical is abnormal." [PomBase:mah] comment: This term was made obsolete because 'drug' is not defined clearly. synonym: "abnormal cellular response to drug during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000212 name: abnormal cellular response to heat def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to heat is abnormal." [PomBase:mah] comment: Use this term if you have assayed the response to heat at the subcellular or molecular level. If you have assayed growth of cells exposed to heat in culture, use 'sensitive to heat' (FYPO:0000082) or 'resistance to heat' (FYPO:0002626). synonym: "abnormal cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000213 name: abnormal vesicle-mediated transport during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is abnormal." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) via vesicles. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "abnormal vesicle-mediated protein transport during vegetative growth" NARROW [PomBase:mah] synonym: "abnormal vesicle-mediated transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000214 name: abnormal mitotic chromosome condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is abnormal." [PomBase:mah] synonym: "abnormal chromosome condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0000159 ! abnormal chromosome condensation created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000215 name: abnormal intracellular protein transport during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which intracellular protein transport is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal intracellular protein transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000540 ! abnormal protein transport during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000216 name: abnormal negative regulation of mitotic DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal. May result in re-replication of all or part of the genome." [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic DNA re-replication" RELATED [PomBase:mah] synonym: "mitotic DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of mitotic DNA replication initiation is_a: FYPO:0004757 ! abnormal negative regulation of DNA replication initiation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000217 name: abnormal DNA replication def: "A cellular process phenotype in which DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000218 name: decreased Mre11 complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of Mre11 complex assembly is decreased." [PomBase:mah] synonym: "decreased Mre11 complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Mre11 complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "MRN complex formation, reduced" EXACT [PomBase:mah] synonym: "reduced Mre11 complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000219 name: increased protein oxidation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "accumulation of carbonylated proteins during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of disulfides during vegetative growth" RELATED [PomBase:al] synonym: "increased level of oxidised thiols in proteins during vegetative growth" RELATED [PomBase:al] synonym: "increased level of oxidized protein thiols during vegetative growth" RELATED [PomBase:mah] synonym: "increased protein oxidation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification during vegetative growth is_a: FYPO:0003863 ! increased protein oxidation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000220 name: increased centromeric outer repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are present at greater levels than normal." [PMID:20211136, PomBase:mah] comment: This term encompasses both unprocessed RNA transcribed from the centromere outer repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'decreased chromatin silencing at centromere outer repeat region' (FYPO:0003412). synonym: "increased accumulation of centromeric outer repeat transcripts" RELATED [PomBase:mah] synonym: "increased accumulation of centromeric outer repeat transcripts during vegetative growth" RELATED [PomBase:mah] synonym: "increased accumulation of non-coding outer repeat transcripts" EXACT [PomBase:vw] synonym: "increased centromere outer repeat transcript level" EXACT [PomBase:mah] synonym: "increased centromeric outer repeat transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased centromeric outer repeat transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "increased centromeric outer repeat-derived transcript level" EXACT [PomBase:vw] synonym: "increased level of centromeric outer repeat transcripts" EXACT [PomBase:mah] is_a: FYPO:0004982 ! increased centromeric transcript level created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000221 name: obsolete transcription regulation phenotype, adaptive response to loss of mtDNA def: "OBSOLETE. A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which the transcription of specific genes is regulated in response to the loss of mitochondrial DNA." [PMID:17868468, PomBase:mah] comment: This term was made obsolete because it was used only to map a legacy vocabulary term that described expression patterns captured by an expression profiling link. synonym: "adaptive expression responses" EXACT [PomBase:mah] synonym: "fission yeast transcription regulation phenotype, adaptive response to loss of mtDNA" EXACT [PomBase:mah] synonym: "transcription regulation phenotype, adaptive response to loss of mtDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "transcription regulation phenotype, adaptive response to loss of mtDNA during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000223 name: elongated multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer, and has a greater length:diameter ratio, than normal, and has more than one septum." [PomBase:mah] synonym: "elongated multiseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated multiseptate cells during vegetative growth" EXACT [PomBase:mah] synonym: "long multiseptate cells" EXACT [PomBase:vw] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0004750 ! elongated septated vegetative cell relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000224 name: lemon-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in the form of a lemon. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc." [http://mathworld.wolfram.com/Lemon.html, PomBase:mah] synonym: "cell morphology, lemon shaped" EXACT [PomBase:mah] synonym: "lemon-shaped cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lemon-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "lemon-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000225 name: snowman-shaped spore def: "A cell morphology phenotype in which a spore assumes a snowman shape, having two connected parts, roughly spherical, of different sizes." [PomBase:mah] synonym: "cell morphology, snowman during sporulation" RELATED [PomBase:mah] synonym: "snowman during sporulation" RELATED [PomBase:mah] is_a: FYPO:0002467 ! abnormal spore shape created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000227 name: chromosome loss during mitotic chromosome segregation def: "A chromosome segregation phenotype observed in the vegetative growth phase of the life cycle in which one or more chromosome or minichromosome is not correctly segregated to either daughter cells during mitosis." [PMID:11809834, PMID:20211136, PomBase:mah] synonym: "chromosome loss during mitotic sister chromatid segregation" EXACT [PomBase:mah] synonym: "chromosome loss during segregation during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome segregation defects, chromosome loss" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000228 name: lagging mitotic chromosomes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sister chromatids do not move towards the spindle poles at the same time during mitosis, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Mitotic sister chromatid segregation may stop before completing separation of chromosomes, or may eventually be completed." [PMID:11809834, PMID:20211136, PomBase:mah] comment: Chromosome lagging may reflect a delay in detachment of sister chromatids from each other ('chromatid separation' as defined by GO:0051306), polewards movement (GO:0007079), or both. Consider also annotating to 'unequal mitotic sister chromatid segregation' (FYPO:0003241) or one of its descendants, because chromosomes that lag at anaphase are often missegregated at telophase. synonym: "chromosome segregation defects, lagging mitotic chromosomes" EXACT [PomBase:mah] synonym: "lagging chromosomes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lagging chromosomes during vegetative growth" EXACT [PomBase:mah] synonym: "lagging mitotic sister chromatids" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0002090 ! lagging chromosomes created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000229 name: cut alt_id: FYPO:0000322 alt_id: FYPO:0000323 def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal mitotic nuclear division, such that the septum physically divides the nucleus into two parts, giving rise to inviable daughter cells." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "cut during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic catastrophe" RELATED [PomBase:vw] synonym: "septation following abnormal nuclear division" EXACT [PomBase:vw] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0001489 ! inviable vegetative cell is_a: FYPO:0003250 ! premature septum assembly relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0003250 ! premature septum assembly created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000230 name: abnormal actomyosin contractile ring actin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filaments and associated proteins does not occur normally, resulting in the formation of an abnormal actomyosin contractile ring in which actin is absent or mislocalized." [GO:2000689, PMID:19713940, PomBase:mah] synonym: "abnormal actomyosin contractile ring actin filament organisation" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring actin filament organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring actin filament organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cytokinetic contractile ring actin filament organization" EXACT [PomBase:vw] synonym: "abnormal mitotic contractile ring actin filament organization" EXACT [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth relationship: part_of FYPO:0000161 ! abnormal actomyosin contractile ring assembly created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000231 name: abnormal actomyosin contractile ring myosin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which myosin filaments are not localized normally within the actomyosin contractile ring." [GO:2000708, PMID:19713940, PomBase:mah] synonym: "abnormal actomyosin contractile ring myosin filament organisation" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring myosin filament organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring myosin filament organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cytokinetic contractile ring myosin filament organization" EXACT [PomBase:vw] synonym: "abnormal mitotic contractile ring myosin filament organization" EXACT [PomBase:vw] synonym: "cytokinesis defects, contractile ring myosin distribution, defective" RELATED [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000232 name: split actomyosin contractile ring def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the actomyosin contractile ring splits upon initiation of contraction during anaphase B, resulting in the formation of a primary ring that undergoes constriction and a secondary ring that does not constrict." [PMID:18272786, PomBase:mah] synonym: "abnormal contractile ring contraction with contractile ring splitting" RELATED [PomBase:mah] synonym: "actomyosin contractile ring splitting" RELATED [PomBase:mah] synonym: "actomyosin contractile ring splitting upon contraction" RELATED [PomBase:mah] synonym: "cytokinesis defects, splitting of the actinomyosin ring" RELATED [PomBase:mah] synonym: "split actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "split actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "split cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "split mitotic contractile ring" EXACT [PomBase:vw] is_a: FYPO:0003338 ! abnormal actomyosin contractile ring morphology created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000233 name: long cytoplasmic microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal." [PomBase:mah] synonym: "elongated cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "long cytoplasmic microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long cytoplasmic microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defect, long cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "microtubule organization defects, long cytoplasmic microtubules" EXACT [PomBase:mah] is_a: FYPO:0000055 ! long microtubules is_a: FYPO:0004088 ! abnormal cytoplasmic microtubules created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000234 name: abnormal cytoplasmic interphase microtubule nucleation def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules is abnormal during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB)." [PMID:19001497, PomBase:mah] synonym: "abnormal cytoplasmic interphase microtubule nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cytoplasmic microtubule nucleation during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cytoplasmic microtubule nucleation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal interphase cytoplasmic microtubule nucleation" EXACT [PomBase:mah] synonym: "abnormal interphase microtubule nucleation" EXACT [PomBase:vw] is_a: FYPO:0005692 ! abnormal microtubule nucleation during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000235 name: abnormal regulation of translation in response to osmotic stress def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to osmotic stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress." [PMID:18065650, PomBase:mah] synonym: "abnormal regulation of translation in response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of translation in response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal translational regulation in response to osmotic stress" EXACT [PomBase:mah] synonym: "defective in recovery of translation after hyperosmotic shock" RELATED [PomBase:mah] is_a: FYPO:0001332 ! abnormal regulation of translation in response to stress during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000236 name: abnormal regulation of translation in response to oxidative stress def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to oxidative stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress." [PMID:18065650, PomBase:mah] synonym: "abnormal regulation of translation in response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of translation in response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal translational regulation in response to oxidative stress" EXACT [PomBase:vw] synonym: "defective in recovery of translation after oxidative stress" RELATED [PomBase:mah] is_a: FYPO:0001332 ! abnormal regulation of translation in response to stress during vegetative growth is_a: FYPO:0001340 ! abnormal cellular response to oxidative stress during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000237 name: abnormal regulation of translation in response to nitrogen starvation def: "A gene expression phenotype in which regulation of translation in response to nitrogen starvation is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels upon prolonged nitrogen starvation." [PMID:18065650, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal regulation of translation in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal regulation of translation in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal translational regulation in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "defective in recovery of translation during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000152 ! abnormal cellular response to nitrogen starvation is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000238 name: inviable cell upon G0 to G1 transition def: "A cell phenotype in which a cell fails to resume growth after several days in G0 phase. The inviable cells show some features characteristic of apoptosis, including loss of DNA." [PMID:19197239, PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. The population term 'loss of viability upon G0 to G1 transition' (FYPO:0006660) may also be relevant. synonym: "abolished mitotic competence upon G0 to G1 transition" RELATED [PomBase:vw] synonym: "die in G0 with an apoptotic-like phenotype" RELATED [PomBase:mah] synonym: "inviable cell upon exit from cell quiescence" EXACT [PomBase:mah] synonym: "inviable cell upon exit from quiescence" EXACT [PomBase:mah] synonym: "lethal in cell upon G0 to G1 transition" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000239 name: increased transcription from MCB promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more MluI cell cycle box factor elements (MCBs) occurs to a greater extent than normal." [PomBase:mah] synonym: "expression of MBF target genes increased" RELATED [PomBase:mah] synonym: "increased transcription from MCB promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from MCB promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000240 name: abnormal filament morphology def: "A cell population phenotype in which the size, shape, or structure of invasively growing filaments is abnormal." [PomBase:mah] synonym: "filament morphology aberrant" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000241 name: obsolete genome stability defects def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which any process that affects the physical integrity, replication, or segregation of genomic DNA is abnormal. Encompasses effects on DNA metabolism, chromosome organization, the spindle assembly checkpoint, and any DNA integrity checkpoint." [PomBase:jh, PomBase:mah, PomBase:vw] comment: This term was made obsolete because it groups a number of somewhat related phenomena, but was not defined clearly or precisely. synonym: "genome stability defects during mitotic cell cycle" RELATED [PomBase:mah] synonym: "genome stability defects during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000242 name: normal growth on ammonia nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing ammonia as the nitrogen source." [PomBase:mah] synonym: "growth defect, normal growth with ammonia nitrogen source" RELATED [PomBase:mah] synonym: "normal cell population growth on ammonia nitrogen source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on ammonia nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000243 name: normal growth on proline nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing L-proline as the nitrogen source." [PomBase:mah] synonym: "growth defect, normal growth with proline nitrogen source" RELATED [PomBase:mah] synonym: "normal cell population growth on proline nitrogen source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on proline nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000244 name: loss of viability upon nutrient depletion def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are deprived of nutrients such as carbon or nitrogen." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under nutrient-depleted conditions, and then the number of cells viable enough to form a colony upon return to nutrient-replete conditions is measured and compared to wild type. Also consider 'sensitive to nitrogen starvation' (FYPO:0002124). synonym: "decreased viability upon nutrient depletion" EXACT [PomBase:mah] synonym: "growth defect, required during nutrient depletion" RELATED [PomBase:mah] synonym: "loss of cell population viability upon nutrient depletion" EXACT [PomBase:mah] synonym: "loss of viability upon nutrient starvation" EXACT [PomBase:al] synonym: "reduced viability upon nutrient depletion" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000245 name: loss of viability in stationary phase def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "decreased chronological lifespan" RELATED [PomBase:vw] synonym: "decreased longevity" EXACT [] synonym: "decreased viability in stationary phase" EXACT [PomBase:mah] synonym: "growth defect, required for stationary phase" RELATED [PomBase:mah] synonym: "increased chronological cell aging" RELATED [PomBase:vw] synonym: "loss of cell population viability in stationary phase" EXACT [PomBase:mah] synonym: "reduced viability in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000246 name: growth auxotrophic for antioxidant def: "A cell population phenotype in which a cell population grows only in the presence of an antioxidant in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "antioxidant required for cell population growth" EXACT [PomBase:mah] synonym: "antioxidant required for growth" EXACT [PomBase:mah] synonym: "antioxidant required for vegetative cell growth" EXACT [PomBase:mah] synonym: "growth defect, requires antioxidant for growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000249 name: decreased cell population growth on ammonia nitrogen source alt_id: FYPO:0000248 def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing ammonia as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on ammonia nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on ammonia nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth in minimal media" RELATED [PomBase:mah] synonym: "growth defect, slow growth with ammonia nitrogen source" NARROW [PomBase:mah] synonym: "reduced cell growth on ammonia nitrogen source" EXACT [PomBase:mah] synonym: "slow cell growth in minimal medium" RELATED [PomBase:mah] synonym: "slow cell growth on ammonia nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000250 name: decreased cell population growth on proline nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-proline as the nitrogen source." [PMID:24344203, PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on proline nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on proline nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth with proline nitrogen source" RELATED [PomBase:mah] synonym: "reduced cell growth on proline nitrogen source" RELATED [PomBase:mah] synonym: "slow cell growth on proline nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000251 name: decreased cell population growth on galactose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing galactose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on galactose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on galactose carbon source" EXACT [PomBase:mah] synonym: "growth defects, growth inhibition in galactose-based medium" RELATED [PomBase:mah] synonym: "reduced cell growth on galactose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on galactose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000252 name: increased spontaneous diploidization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells spontaneously form cells with diploid DNA content at a higher frequency than normal." [PMID:19101542, PomBase:mah] synonym: "high-frequency diploidization in heterothallic strains" EXACT [PomBase:mah] synonym: "increased spontaneous diploidisation" EXACT [PomBase:mah] synonym: "increased spontaneous diploidization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spontaneous diploidization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype relationship: has_output FYPO:0000158 ! DNA content increased during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000253 name: increased HMG-CoA reductase activity def: "A molecular function phenotype in which the observed rate of hydroxymethylglutaryl-CoA reductase (NADPH) activity is increased." [PMID:19041767, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000254 name: increased protein processing during vegetative growth def: "A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the observed occurrence of protein processing is increased." [PMID:19520858, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased Sre1 cleavage" NARROW [PomBase:mah] is_a: FYPO:0001421 ! abnormal protein processing during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000255 name: increased nuclear protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in the cell nucleus is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PMID:12896976, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased nuclear protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level in nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "localization defects, nuclear accumulation of Pap1 and Sty1" NARROW [PomBase:mah] synonym: "nuclear accumulation of Pap1 and Sty1" NARROW [PomBase:mah] synonym: "nuclear accumulation of protein" EXACT [PomBase:mah] synonym: "nuclear protein accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0002403 ! abnormal nucleus created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000256 name: mutator def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a higher frequency than normal." [PomBase:mah] synonym: "increased mutation rate" EXACT [PomBase:vw] synonym: "mutator during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mutator during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007431 ! altered mutation rate created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000257 name: normal phenotype def: "A phenotype that shows no detectable differences from normal. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast normal phenotype" EXACT [PomBase:mah] synonym: "no obvious phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype relationship: inheres_in FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000258 name: obsolete normal phenotype during exponential phase def: "OBSOLETE. A cell phenotype that shows no detectable differences from normal during exponential growth." [PomBase:mah] comment: This term was made obsolete because it was not sufficiently distinguished from its parent. synonym: "fission yeast normal phenotype during exponential phase" EXACT [PomBase:mah] synonym: "no phenotype in exponential phase" EXACT [PomBase:mah] synonym: "normal phenotype during exponential phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phenotype during exponential phase during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000260 name: abnormal G1/S phase transcription def: "A gene expression phenotype in which regulation of transcription during the G1/S phase of the cell cycle is abnormal." [PomBase:mah] synonym: "abnormal G1/S phase transcription during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal G1/S phase transcription during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of transcription involved in G1/S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "periodic cell-cycle expression, abolished" RELATED [PomBase:mah] is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000261 name: obsolete pleiotropic effects def: "OBSOLETE. Multiple different phenotypes due to a single mutation." [PomBase:mah] comment: This term was made obsolete because genes, alleles, etc. can be annotated with multiple specific phenotype terms. synonym: "pleiotropic effects during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000262 name: abnormal cellular response to reactive oxygen species during G0 def: "A cell phenotype in which cells do not respond normally to reactive oxygen species, resulting in accumulation of oxidative damage including DNA damage, during G0 phase." [PMID:19197239, PomBase:mah] synonym: "abnormal cellular response to reactive oxygen species during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal cellular response to reactive oxygen species during quiescence" EXACT [PomBase:mah] synonym: "protects against physiological oxidative damage in G0" RELATED [PomBase:mah] is_a: FYPO:0000180 ! abnormal cellular response to oxidative stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000263 name: abnormal regulation of translation in response to stress def: "A gene expression phenotype in which regulation of translation in response to stress is abnormal." [PomBase:mah] synonym: "protein synthesis after stress, defective" RELATED [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress is_a: FYPO:0000289 ! translation regulation phenotype is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000264 name: resistance to microtubule-destabilizing substance def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of a microtubule-destabilizing substance than normal." [PomBase:mah] synonym: "resistance to microtubule depolymerizing drugs" EXACT [PomBase:mah] synonym: "resistance to microtubule destabilising substance" EXACT [PomBase:mah] synonym: "resistance to microtubule-destabilizing substance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to microtubule-destabilizing substance during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to microtubule-destabilizing substance" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000265 name: sensitive to DNA damage def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to DNA damage." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to DNA damage in culture. If you have assayed the response to DNA damage at the subcellular or molecular level, consider annotating to 'abnormal cellular response to DNA damage stimulus' (FYPO:0000157). Also consider specific phenotype terms for sensitivity to substances or other stimuli that can damage DNA, e.g. 'sensitive to DNA damaging agents' (FYPO:0000266), 'sensitive to methyl methanesulfonate' (FYPO:0000089), 'sensitive to UV' (FYPO:0000268), etc. synonym: "decreased growth during cellular response to DNA damage" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to DNA damage" EXACT [PomBase:mah] synonym: "hypersensitive to DNA damage" EXACT [PomBase:mah] synonym: "sensitive to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000266 name: sensitive to DNA damaging agents def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a genotoxin, any chemical compound that can act to induce direct or indirect DNA damage. Cells stop growing (and may die) at a concentration of a DNA damaging agent that allows wild type cells to grow." [CHEBI:50902, PomBase:mah] synonym: "hypersensitive to DNA damaging agents" EXACT [PomBase:mah] synonym: "sensitive to DNA damaging agents during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to DNA damaging agents during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000267 name: sensitive to ionizing radiation during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ionizing radiation." [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "hypersensitive to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to gamma irradiation during vegetative growth" NARROW [PomBase:al] synonym: "sensitive to gamma radiation during vegetative growth" NARROW [PomBase:al] synonym: "sensitive to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to IR during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000268 name: sensitive to UV during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light." [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to UV" EXACT [PomBase:mah] synonym: "hypersensitive to UV during vegetative growth" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation during vegetative growth" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "UV resistance: decreased during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth is_a: FYPO:0002550 ! sensitive to UV created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000269 name: sensitive to microtubule depolymerizing drugs def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a microtubule-destabilizing substance. Cells stop growing (and may die) at a concentration of a microtubule-depolymerizing drug that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to microtubule depolymerizing drugs" EXACT [PomBase:mah] synonym: "sensitive to microtubule depolymerizing drugs during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to microtubule depolymerizing drugs during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000270 name: sensitive to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to osmotic stress." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to osmotic stress in culture. If you have assayed the response to osmotic stress at the subcellular or molecular level, consider annotating to 'abnormal cellular response to osmotic stress' (FYPO:0000193). synonym: "hypersensitive to osmotic stress" EXACT [PomBase:mah] synonym: "osmotic stress resistance: decreased" RELATED [SGD:phenotype_annotation] synonym: "sensitive to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000271 name: sensitive to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a salt stress." [PomBase:mah] synonym: "hypersensitive to salt stress" EXACT [PomBase:mah] synonym: "ionic stress resistance: decreased" RELATED [SGD:phenotype_annotation] synonym: "sensitive to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000272 name: abolished septum assembly def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell fails to form a septum." [PMID:9649519, PomBase:mah] synonym: "abolished division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "abolished septation" BROAD [GO:0000917, PomBase:mah] synonym: "abolished septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished septum formation" EXACT [PomBase:mah] synonym: "septum assembly abolished" EXACT [PomBase:mah] synonym: "septum assembly abolished during vegetative growth" EXACT [PomBase:mah] synonym: "septum formation: absent" RELATED [SGD:phenotype_annotation] synonym: "septum initiation defective" RELATED [PomBase:mah] is_a: FYPO:0000117 ! abnormal septum assembly is_a: FYPO:0000417 ! abolished cytokinesis created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000273 name: centromeric outer repeat transcripts absent def: "An RNA metabolism phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are absent." [PMID:20211136, PomBase:mah] comment: This term encompasses both unprocessed RNA transcribed from the centromere outer repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'abnormal chromatin silencing at centromere outer repeat region' (FYPO:0002346). synonym: "centromere outer repeat transcripts absent" EXACT [PomBase:mah] synonym: "centromeric outer repeat transcripts absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "centromeric outer repeat transcripts absent during vegetative growth" EXACT [PomBase:mah] synonym: "centromeric outer repeat-derived transcripts absent" EXACT [PomBase:vw] is_a: FYPO:0003094 ! decreased centromeric outer repeat transcript level is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000274 name: increased duration of mitotic M phase alt_id: FYPO:0000609 alt_id: FYPO:0004234 def: "A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is longer than normal." [PomBase:mah] synonym: "delayed mitotic M phase progression" RELATED [PomBase:mah] synonym: "delayed mitotic M phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of M phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of mitosis" RELATED [PomBase:mah] synonym: "increased duration of mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of mitosis during vegetative growth" RELATED [PomBase:mah] synonym: "increased duration of mitotic nuclear division" RELATED [PomBase:mah] synonym: "increased mitotic M phase duration" EXACT [PomBase:mah] synonym: "increased mitotic M phase duration during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in M phase: delayed" RELATED [SGD:phenotype_annotation] synonym: "prolonged mitosis" RELATED [PomBase:mah] synonym: "prolonged mitotic M phase" EXACT [PomBase:mah] synonym: "spindle checkpoint activated" RELATED [PomBase:mah] is_a: FYPO:0000607 ! abnormal mitotic M phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase relationship: has_output FYPO:0000420 ! delayed onset of cytokinesis created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000275 name: obsolete spindle checkpoint required def: "OBSOLETE. A cell cycle phenotype in which cells are viable only if a spindle checkpoint functions normally." [PMID:15483052, PomBase:mah] comment: This term was made obsolete because it was used to represent two different phenotypes. is_obsolete: true consider: FYPO:0000029 consider: FYPO:0000324 consider: FYPO:0000333 created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000276 name: monopolar mitotic spindle def: "A physical cellular phenotype in which the mitotic spindle forms with microtubules emanating from only one pole." [PMID:11792803, PMID:9763447, PomBase:mah] comment: Also consider annotating to 'abnormal spindle pole body separation' (FYPO:0001733) or one of its children. synonym: "fan-shaped mitotic spindle" EXACT [PomBase:vw] synonym: "monopolar mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "monopolar spindle during mitosis" EXACT [PomBase:mah] synonym: "monopolar spindle during mitotic cell cycle" EXACT [PomBase:mah] synonym: "spindle defects, monopolar mitotic spindle" EXACT [PomBase:mah] synonym: "spindle defects, monopolar spindle" EXACT [PomBase:mah] synonym: "V-shaped mitotic spindle" RELATED [PomBase:vw] is_a: FYPO:0000338 ! abnormal mitotic spindle relationship: output_of FYPO:0005344 ! abolished mitotic spindle midzone assembly created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000278 name: decreased cell population growth following spore germination def: "A cell population phenotype in which cell population growth is decreased following spore germination, resulting in the formation of a smaller colony than normal in a given amount of time." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth following spore germination" BROAD [PomBase:mah] synonym: "reduced cell population growth following spore germination" EXACT [PomBase:mah] synonym: "slow cell population growth following spore germination" NARROW [PomBase:mah] synonym: "spores produced smaller colonies" RELATED [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000279 name: obsolete formation of azygotic ascus upon sporulation def: "OBSOLETE. A sporulation phenotype in which azygotic asci form following conjugation and subsequent sporulation. Azygotic ascus formation occurs when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:16169489, PMID:18780734, PMID:20404563, PomBase:mah] comment: This term was made obsolete because it was incorrectly defined. Although the description in the text definition is accurate, azygotic sporulation is not necessarily an abnormal occurrence. The term was also used incorrectly in annotations. synonym: "abnormal sporulation resulting in formation of azygotic asci" EXACT [PomBase:mah] synonym: "formation of azygotic asci upon sporulation" EXACT [PomBase:mah] synonym: "sporulation defects, azygotic asci" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000280 name: sterile alt_id: FYPO:0000638 def: "A cellular process phenotype in which conjugation does not occur." [PomBase:mah] synonym: "conjugation abolished" EXACT [PomBase:mah] synonym: "zygote formation abolished" RELATED [PomBase:mah] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000281 name: small vacuoles present in increased numbers during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more, but smaller, vacuoles than normal." [PomBase:mah] synonym: "fragmented vacuoles during vegetative growth" RELATED [PomBase:mah] synonym: "small vacuoles present in greater numbers during vegetative growth" EXACT [PomBase:mah] synonym: "small vacuoles present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vacuole fusion defects" RELATED [PomBase:vw] synonym: "vacuole organization defects, fragmented vacuoles during vegetative growth" RELATED [PomBase:mah] synonym: "vacuoles present in increased numbers, with decreased vacuole size, during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000952 ! vacuoles present in increased numbers during vegetative growth is_a: FYPO:0002258 ! small vacuoles present in increased numbers relationship: has_part FYPO:0000952 ! vacuoles present in increased numbers during vegetative growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000282 name: obsolete viable cell at high temperature def: "OBSOLETE. A viability phenotype observed in the vegetative growth phase of the life cycle in which a cell is able to survive at a high temperature." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the cell viability term with conditions specified. synonym: "cell viable at high temperature" EXACT [PomBase:mah] synonym: "viable cell at high temperature during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable cell at high temperature during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000283 name: mitotic chromosome fragmentation upon segregation def: "A chromosome segregation phenotype in which chromosomes are broken during mitotic chromosome segregation." [PomBase:mah] synonym: "chromosome fragmentation upon mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "chromosome fragmentation upon segregation during mitosis" EXACT [PomBase:mah] synonym: "chromosome fragmentation upon segregation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "chromosome fragmentation upon segregation during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome segregation defects, chromosome fragmentation" EXACT [PomBase:mah] synonym: "fragmented mitotic chromosomes upon segregation" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000284 name: large and small daughter nuclei, with unequal mitotic sister chromatid segregation def: "A mitosis phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes unequal mitotic sister chromatid segregation, and as a result the nucleus divides unequally to produce one daughter nucleus that is larger than the other." [PMID:8769419, PomBase:jh, PomBase:mah, PomBase:vw] synonym: "complete but unequal mitotic sister chromatid segregation forming large and small daughter nuclei" EXACT [PomBase:mah] synonym: "large and small daughter nuclei resulting from unequal mitotic sister chromatid segregation" RELATED [PomBase:mah] synonym: "large and small daughter nuclei, with complete but unequal mitotic sister chromatid segregation" EXACT [PomBase:mah] synonym: "large and small daughter nuclei, with unequal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "large and small daughter nuclei, with unequal mitotic sister chromatid segregation, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large and small daughter nuclei, with unequal mitotic sister chromatid segregation, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006715 ! large and small daughter nuclei relationship: output_of FYPO:0001270 ! complete but unequal mitotic sister chromatid segregation created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000286 name: sensitive to manganese depletion def: "A cell population phenotype observed in the vegetative growth phase of the life cycle in which a population of cells grow poorly in medium that has a low concentration of manganese (Mn2+)." [PMID:14723709, PomBase:mah] synonym: "hypersensitive to manganese depletion" EXACT [PomBase:mah] synonym: "sensitive to manganese depletion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to manganese depletion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth created_by: midori creation_date: 2011-04-20T01:42:21Z [Term] id: FYPO:0000287 name: abnormal subcellular component def: "A physical cellular phenotype in which the amount, distribution, composition or morphology of a cell part is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal subcellular component physical object quality" EXACT [PomBase:mah] synonym: "abnormal subcellular structure" RELATED [PomBase:mah] is_a: FYPO:0000136 ! cellular physical quality phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-21T11:18:18Z [Term] id: FYPO:0000288 name: gene expression regulation phenotype def: "A regulation phenotype that affects the regulation of gene expression." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast gene expression regulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000145 ! regulation phenotype created_by: midori creation_date: 2011-04-21T02:22:36Z [Term] id: FYPO:0000289 name: translation regulation phenotype def: "A gene expression phenotype that affects the regulation of translation." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast translation regulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype created_by: midori creation_date: 2011-04-21T02:25:06Z [Term] id: FYPO:0000290 name: transcription phenotype during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects DNA-dependent transcription." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "transcription phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004847 ! transcription phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000291 name: translation phenotype def: "A cellular process phenotype that affects translation." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast translation phenotype" EXACT [PomBase:mah] synonym: "translation phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "translation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000292 name: nucleic acid metabolism phenotype def: "A cellular process phenotype that affects any nucleic acid metabolic process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast nucleic acid metabolism phenotype" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000293 name: DNA metabolism phenotype def: "A cellular process phenotype that affects any DNA metabolic process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast DNA metabolism phenotype" EXACT [PomBase:mah] is_a: FYPO:0000292 ! nucleic acid metabolism phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000294 name: RNA metabolism phenotype def: "A cellular process phenotype that affects any RNA metabolic process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast RNA metabolism phenotype" EXACT [PomBase:mah] synonym: "RNA metabolism phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000292 ! nucleic acid metabolism phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000295 name: cytoskeleton organization phenotype def: "A cellular process phenotype that affects cytoskeleton organization. Cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GO:0007010, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cytoskeleton organisation phenotype" EXACT [PomBase:mah] synonym: "fission yeast cytoskeleton organization phenotype" EXACT [PomBase:mah] is_a: FYPO:0000334 ! cellular component organization phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000296 name: actin cytoskeleton organization phenotype def: "A cellular process phenotype that affects the organization of the actin cytoskeleton. Actin cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and associated proteins." [GO:0030036, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton morphology' (FYPO:0000350), but note that an abnormal cytoskeleton organization process may, but does not necessarily, result in abnormal cytoskeleton morphology. synonym: "actin cytoskeleton organisation phenotype" EXACT [PomBase:mah] synonym: "actin cytoskeleton organization phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cytoskeleton organization phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast actin cytoskeleton organization phenotype" EXACT [PomBase:mah] is_a: FYPO:0000295 ! cytoskeleton organization phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000297 name: microtubule cytoskeleton organization phenotype def: "A cellular process phenotype that affects the organization of the microtubule cytoskeleton. Microtubule cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and associated proteins." [GO:0000226, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast microtubule cytoskeleton organization phenotype" EXACT [PomBase:mah] synonym: "microtubule cytoskeleton organisation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000295 ! cytoskeleton organization phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000298 name: cellular response phenotype def: "A cellular process phenotype that affects a response to a stimulus." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cellular response phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-21T04:47:15Z [Term] id: FYPO:0000299 name: obsolete inviable microcolony def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony formation" EXACT [PomBase:mah] synonym: "microcolony formation" BROAD [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-26T02:13:39Z [Term] id: FYPO:0000300 name: biological process phenotype def: "A phenotype that affects a biological process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast biological process phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-04-26T02:25:13Z [Term] id: FYPO:0000301 name: mating phenotype def: "A biological process phenotype that affects conjugation." [PomBase:mah] synonym: "conjugation phenotype" EXACT [PomBase:mah] synonym: "fission yeast mating phenotype" EXACT [PomBase:mah] is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-04-26T02:29:20Z [Term] id: FYPO:0000302 name: abnormal response to pheromone def: "A conjugation phenotype in which a cell's response to mating pheromone is abnormal." [PomBase:mah] synonym: "abnormal response to pheromone involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "defective response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype created_by: midori creation_date: 2011-04-26T02:36:20Z [Term] id: FYPO:0000303 name: decreased conjugation frequency def: "A cell population phenotype in which a smaller than normal proportion of cells in the population undergoes conjugation." [PomBase:mah] comment: Note that this term refers specifically to conjugation, whereas experiments that measure mating efficiency often do so by counting zygotes plus asci, sometimes also including spores. For such experiments, we recommend using 'decreased mating efficiency' (FYPO:0000708). synonym: "decreased conjugation efficiency" RELATED [PomBase:mah] synonym: "decreased mating frequency" EXACT [PomBase:mah] synonym: "decreased occurrence of mating" EXACT [PomBase:mah] synonym: "reduced conjugation efficiency" RELATED [PomBase:mah] synonym: "reduced conjugation frequency" EXACT [PomBase:mah] synonym: "reduced zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-26T02:40:00Z [Term] id: FYPO:0000304 name: sensitive to stress during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a stress. Typically, a cell population is deemed sensitive to a stress if cells in the population stop growing (and may die) when exposed to the stress at an intensity that allows a population of wild type cells to grow and divide." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to a stress in culture. If you have assayed the response to the stress at the subcellular or molecular level, consider annotating to 'abnormal cellular response to stress during vegetative growth' (FYPO:0001341). synonym: "decreased growth during cellular response to stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to stress during vegetative growth" EXACT [PomBase:mah] synonym: "hypersensitive to stress during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "stress resistance: decreased during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001358 ! vegetative cell population growth phenotype is_a: FYPO:0002549 ! sensitive to stress created_by: midori creation_date: 2011-04-26T03:10:44Z [Term] id: FYPO:0000305 name: abnormal spore germination def: "A cellular process phenotype in which spore germination is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000307 name: inviable small spore def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and is smaller than normal. An inviable spore does not germinate." [PomBase:mah] synonym: "lethal; small spore" EXACT [PomBase:mah] synonym: "spore germination abolished, small spores" RELATED [PomBase:mah] is_a: FYPO:0000309 ! inviable spore with abnormal morphology is_a: FYPO:0000346 ! small spores created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000309 name: inviable spore with abnormal morphology def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has an abnormal morphology (i.e. size, shape, or structure). An inviable spore does not germinate." [PomBase:mah] synonym: "lethal; spore with abnormal morphology" EXACT [PomBase:mah] synonym: "spore germination abolished, abnormal spore morphology" RELATED [PomBase:mah] synonym: "spore germination abolished, misshapen spores" RELATED [PomBase:mah] is_a: FYPO:0000348 ! abnormal spore morphology is_a: FYPO:0002151 ! inviable spore created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000310 name: inviable after spore germination, without cell division, with normal germ tube morphology def: "A phenotype in which a spore germinates to produce a normal germ tube, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination, undivided cell with normal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, with normal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with normal germ tube morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with normal germ tube morphology" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000311 name: inviable after spore germination with normal, unseptated germ tube morphology def: "A phenotype in which a spore germinates to produce a normal germ tube, but does not septate or go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable following spore germination with normal, unseptated germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore with normal, unseptated germ tube morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination with normal, unseptated germ tube morphology" EXACT [PomBase:mah] is_a: FYPO:0000310 ! inviable after spore germination, without cell division, with normal germ tube morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000312 name: inviable after spore germination with normal, septated germ tube morphology def: "A phenotype in which a spore germinates to produce a normal germ tube, and undergoes septation, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable following spore germination with normal, septated germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore with normal, septated germ tube morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination with normal, septated germ tube morphology" EXACT [PomBase:mah] is_a: FYPO:0000310 ! inviable after spore germination, without cell division, with normal germ tube morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000313 name: inviable after spore germination, without cell division, with abnormal germ tube morphology def: "A phenotype in which a spore germinates to produce a germ tube with abnormal morphology (i.e. size, shape, or structure), and does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination, undivided cell with abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division with abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with abnormal germ tube morphology" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000314 name: inviable after spore germination with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and does not go on to give rise to a viable cell population." [PomBase:mah] synonym: "inviable after spore germination, elongated cell" EXACT [PomBase:mah] synonym: "inviable following spore germination with elongated germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore with elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination with elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002281 ! inviable after spore germination with abnormal germ tube morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000315 name: inviable after spore germination, without cell division, with elongated, septated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and undergoes septation, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination, without cell division, elongated, septated cell" EXACT [PomBase:mah] synonym: "inviable following spore germination with elongated, septated germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with elongated, septated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with elongated, septated germ tube" EXACT [PomBase:mah] is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology is_a: FYPO:0004750 ! elongated septated vegetative cell created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000316 name: inviable after spore germination def: "A viability phenotype in which a spore germinates but fails to produce dividing cells that can survive under normal conditions." [PomBase:jh, PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable germinated spore" EXACT [PomBase:mah] synonym: "inviable germinating spore" RELATED [PomBase:mah] synonym: "lethal after spore germination" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2011-04-27T01:13:41Z [Term] id: FYPO:0000317 name: obsolete mixed population def: "OBSOLETE. A cell population phenotype in which a population contains cells with more than one phenotype, usually different morphologies." [PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2011-04-27T01:32:52Z [Term] id: FYPO:0000318 name: obsolete inviable mixed population including long cells def: "OBSOLETE. A mixed population phenotype in which a microcolony forms, all cells in the population are inviable, some cells may divide, and some cells are longer than normal." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable microcolony including long cells" EXACT [PomBase:mah, PomBase:vw] synonym: "inviable mixed population including long vegetative cells" EXACT [PomBase:mah] synonym: "long low penetrance" RELATED [PomBase:jh, PomBase:vw] is_obsolete: true created_by: midori creation_date: 2011-04-27T04:18:16Z [Term] id: FYPO:0000319 name: obsolete inviable mixed population including spores and divided germinated spores def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of spores and germinated spores most of which go on to divide once or twice. Some germinated spores remain septated and do not complete cell division." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "put cut" RELATED [PomBase:jh] is_obsolete: true created_by: midori creation_date: 2011-04-27T04:20:40Z [Term] id: FYPO:0000320 name: inviable after spore germination, single cell division, normal cell morphology def: "A phenotype in which a spore germinates to produce a cell of normal morphology (i.e. size, shape, and structure) that undergoes a single round of cell division, and then dies." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable following spore germination, single cell division, normal cell morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division, normal cell morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division, normal cell morphology" EXACT [PomBase:mah] is_a: FYPO:0002199 ! inviable vegetative cell with normal cell morphology is_a: FYPO:0002280 ! inviable after spore germination, single cell division created_by: midori creation_date: 2011-04-27T04:25:13Z [Term] id: FYPO:0000321 name: obsolete inviable mixed population including spores and undivided germinated spores def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores and germinated spores that fail to divide." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2011-04-27T04:32:25Z [Term] id: FYPO:0000324 name: mitotic metaphase/anaphase transition delay alt_id: FYPO:0000393 alt_id: FYPO:0004309 def: "A cell cycle phenotype in which the onset of anaphase of the mitotic cell cycle begins later than normal." [PomBase:mah] comment: Often anaphase onset and anaphase B onset are used interchangeably since they are stablished by monitoring cdc13 levels or the switch from phase II to III of spindle elongation. Also, I am not aware of any phenotype where anaphase A starts but anaphase B does not. {xref="PomBase:mlr"} synonym: "cell cycle passage through the metaphase-anaphase transition: delayed" RELATED [SGD:phenotype_annotation] synonym: "delayed cell cycle passage through mitotic metaphase-anaphase transition" EXACT [PomBase:mah] synonym: "delayed mitotic anaphase B" NARROW [PomBase:mah] synonym: "delayed mitotic metaphase/anaphase transition" EXACT [] synonym: "delayed onset of anaphase B during mitotic cell cycle" NARROW [PomBase:mah] synonym: "delayed onset of mitotic anaphase" EXACT [PomBase:vw] synonym: "delayed onset of mitotic anaphase" EXACT [PomBase:mah] synonym: "delayed onset of mitotic anaphase B" NARROW [] synonym: "delayed onset of mitotic anaphase B during vegetative growth" NARROW [PomBase:mah] synonym: "increased duration of metaphase during mitosis" RELATED [PomBase:mah] synonym: "increased duration of mitotic metaphase" RELATED [PomBase:mah] synonym: "metaphase/anaphase transition delay during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic anaphase delay" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay at metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "mitotic metaphase/anaphase transition delay during vegetative growth" EXACT [PomBase:mah] synonym: "transient cell cycle arrest in mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0006477 ! abnormal mitotic metaphase/anaphase transition relationship: has_output FYPO:0000274 ! increased duration of mitotic M phase created_by: midori creation_date: 2011-05-09T04:36:10Z [Term] id: FYPO:0000325 name: abnormal attachment of spindle microtubules to kinetochore def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-05-11T01:50:15Z [Term] id: FYPO:0000326 name: abnormal mitotic sister chromatid biorientation def: "A cellular process phenotype in which the stable attachment of sister chromatids to microtubules emanating from opposite poles of the mitotic spindle during metaphase plate congression is abnormal." [PomBase:mah] comment: This term is more specific than 'abnormal attachment of mitotic spindle microtubules to kinetochore' (FYPO:0004213) because sister chromatid biorientation normally occurs only as part of metaphase plate congression, not during other stages of mitosis. FYPO:0004213 can be used for abnormal attachment observed at any time during mitosis. Consider also annotating to 'unequal mitotic sister chromatid segregation' (FYPO:0003241) because a problem with biorientation usually results in unequal chromosome segregation. synonym: "abnormal sister chromatid biorientation during mitosis" EXACT [PomBase:mah] synonym: "abnormal sister chromatid biorientation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal sister chromatid biorientation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore created_by: midori creation_date: 2011-05-11T01:51:05Z [Term] id: FYPO:0000327 name: resistance to trichostatin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of trichostatin A than normal." [PomBase:mah] synonym: "resistance to trichostatin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to trichostatin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to trichostatin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-05-11T02:55:53Z [Term] id: FYPO:0000328 name: abnormal protein metabolic process during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects protein metabolism in the cell." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal cellular protein metabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein metabolic process during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth is_a: FYPO:0002274 ! abnormal protein metabolic process created_by: midori creation_date: 2011-05-11T03:39:46Z [Term] id: FYPO:0000329 name: abnormal protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein/peptide modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000328 ! abnormal protein metabolic process during vegetative growth is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2011-05-11T03:40:46Z [Term] id: FYPO:0000330 name: abnormal histone modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects histone modification." [PomBase:mah] synonym: "abnormal histone modification during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0006458 ! abnormal histone modification created_by: midori creation_date: 2011-05-11T03:41:32Z [Term] id: FYPO:0000331 name: decreased histone acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000456 ! abnormal histone acetylation during vegetative growth created_by: midori creation_date: 2011-05-11T03:42:20Z [Term] id: FYPO:0000332 name: increased histone acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000456 ! abnormal histone acetylation during vegetative growth created_by: midori creation_date: 2011-05-11T03:43:21Z [Term] id: FYPO:0000333 name: mitotic G1/S phase transition delay alt_id: FYPO:0000396 alt_id: FYPO:0000480 alt_id: FYPO:0000543 def: "A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle begins later than normal. The duration of G1 phase is thus longer than normal." [PomBase:mah] comment: A G1/S delay may indicate that a checkpoint, such as the cell size checkpoint or the G1/S DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "cell cycle progression through the G1/S phase transition: delayed" RELATED [SGD:phenotype_annotation] synonym: "delayed cell cycle progression through mitotic G1/S phase transition" EXACT [PomBase:mah] synonym: "delayed mitotic G1 phase progression" RELATED [PomBase:mah] synonym: "G1/S transition delay during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of mitotic G1 phase" RELATED [PomBase:mah] synonym: "increased duration of mitotic G1 phase during vegetative growth" RELATED [PomBase:mah] synonym: "increased duration of mitotic G1 phase progression" RELATED [PomBase:mah] synonym: "mitotic cell cycle delay at G1/S transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay in G1" RELATED [PomBase:mah] synonym: "mitotic G1/S phase transition delay during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic G1/S transition delay" EXACT [PomBase:mah] synonym: "transient cell cycle arrest in mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000394 ! abnormal mitotic G1/S phase transition is_a: FYPO:0000409 ! delayed cell cycle phase transition is_a: FYPO:0000602 ! abnormal mitotic G1 phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase is_a: FYPO:0005275 ! abnormal mitotic cell cycle phase transition created_by: midori creation_date: 2011-05-11T04:08:59Z [Term] id: FYPO:0000334 name: cellular component organization phenotype def: "A phenotype that affects a process of cellular component organization, i.e. the assembly, arrangement of constituent parts, or disassembly of a cellular component, that occurs at the cellular level." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cellular component organisation phenotype" EXACT [PomBase:mah] synonym: "cellular component organization phenotype at cellular level" EXACT [PomBase:mah] synonym: "fission yeast cellular component organization phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-06-03T11:55:29Z [Term] id: FYPO:0000335 name: abnormal cellular component organization def: "A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal." [GO:0016043, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular component organisation" EXACT [PomBase:mah] synonym: "abnormal cellular component organization at cellular level" EXACT [PomBase:mah] is_a: FYPO:0000334 ! cellular component organization phenotype created_by: midori creation_date: 2011-06-03T11:57:14Z [Term] id: FYPO:0000336 name: abnormal cellular component assembly def: "A cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular component assembly at cellular level" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2011-06-03T12:00:35Z [Term] id: FYPO:0000337 name: abnormal mitosis def: "A cellular process phenotype in which mitosis is abnormal." [PomBase:mah] synonym: "abnormal mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal nuclear division during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000186 ! abnormal cell division during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2011-06-03T12:29:47Z [Term] id: FYPO:0000338 name: abnormal mitotic spindle alt_id: FYPO:0000277 def: "A physical cellular phenotype in which the position or morphology of the mitotic spindle is abnormal." [PomBase:mah] synonym: "abnormal mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic spindle defects" EXACT [PomBase:mah] synonym: "spindle polarity defects" RELATED [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2011-06-03T01:43:41Z [Term] id: FYPO:0000339 name: mislocalized septum during vegetative growth alt_id: FYPO:0002154 def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in an abnormal location. The normal location is at the midpoint of the long axis of the cell. The site of septum assembly is normally determined by the location of the actomyosin contractile ring." [PomBase:mah] comment: Note that the location of the septum is determined by the location of the contractile ring, which in turn is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. Consider also annotating to 'mislocalized actomyosin contractile ring' (FYPO:0001369) because if the contractile ring forms in an abnormal location, the septum will also do so. synonym: "abnormal contractile ring localization resulting in abnormal septum site selection" RELATED [PomBase:mah] synonym: "abnormal contractile ring localization resulting in mislocalized septum" RELATED [PomBase:mah] synonym: "abnormal division septum site selection" RELATED [PomBase:mah] synonym: "abnormal septum localization during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal septum location during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal septum position during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal septum positioning during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal septum postitioning" EXACT [] synonym: "abnormal septum site selection" RELATED [PomBase:mah] synonym: "abnormal septum site selection during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septum site selection during vegetative growth" RELATED [PomBase:mah] synonym: "asymmetric septum during vegetative growth" EXACT [PomBase:mah] synonym: "asymmetrically located septum during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalised septum during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "misplaced septum during vegetative growth" EXACT [PomBase:vw] synonym: "septum site selection defects" RELATED [PomBase:mah] is_a: FYPO:0002455 ! abnormal septum during vegetative growth is_a: FYPO:0004293 ! mislocalized septum relationship: output_of FYPO:0000033 ! abnormal actomyosin contractile ring localization created_by: midori creation_date: 2011-06-13T02:57:21Z [Term] id: FYPO:0000340 name: haploinsufficient def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a single functional copy of a gene does not provide sufficient normal function in a diploid cell." [PomBase:mah] synonym: "haploinsufficient during mitotic cell cycle" RELATED [PomBase:mah] synonym: "haploinsufficient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2011-06-13T04:23:38Z [Term] id: FYPO:0000341 name: haplosufficient def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a single functional copy of a gene provides sufficient normal function in a diploid cell." [PomBase:mah] synonym: "haplosufficient during mitotic cell cycle" RELATED [PomBase:mah] synonym: "haplosufficient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2011-06-13T04:25:07Z [Term] id: FYPO:0000342 name: decreased cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular respiration is decreased." [PomBase:mah] synonym: "decreased cellular respiration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "decreased respiration" BROAD [PomBase:mah] synonym: "decreased respiratory metabolism" EXACT [PomBase:mah] synonym: "reduced cellular respiration" EXACT [PomBase:mah] synonym: "respiratory metabolism: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-06-14T04:25:19Z [Term] id: FYPO:0000343 name: increased concentration of hydrogen sulfide in growth medium def: "A phenotype in which the concentration of hydrogen sulfide released into the growth medium by cells is higher than normal." [PomBase:mah] synonym: "increased concentration of H2S in growth medium" EXACT [PomBase:mah] synonym: "increased hydrogen sulfide biosynthesis" RELATED [PomBase:mah] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2011-06-14T04:44:26Z [Term] id: FYPO:0000344 name: enlarged nucleus during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is larger than normal." [PomBase:mah] comment: Consider also annotating to 'increased nucleus:cytoplasm ratio' (FYPO:0006926). synonym: "enlarged nuclei during vegetative growth" EXACT [PomBase:vw] synonym: "enlarged nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth is_a: FYPO:0002255 ! enlarged nucleus created_by: midori creation_date: 2011-06-15T03:45:06Z [Term] id: FYPO:0000345 name: abnormal protein export from nucleus during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus is abnormal. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: Encompasses both export of proteins normally retained in the nucleus and nuclear retention of normally exported proteins. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport during vegetative growth is_a: FYPO:0000506 ! abnormal nuclear export is_a: FYPO:0005745 ! abnormal protein export from nucleus created_by: midori creation_date: 2011-06-15T05:11:00Z [Term] id: FYPO:0000346 name: small spores def: "A cell morphology phenotype in which spores have an abnormally low volume." [PomBase:mah] synonym: "decreased spore size" EXACT [PomBase:mah] synonym: "reduced spore size" EXACT [PomBase:mah] is_a: FYPO:0000023 ! small cell is_a: FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2011-07-07T03:26:17Z [Term] id: FYPO:0000347 name: swollen spore def: "A cell morphology phenotype in which a spore has a larger volume than normal. In a swollen cell, both length and diameter are greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "enlarged spore" RELATED [PomBase:mah] synonym: "increased spore size" RELATED [PomBase:vw] synonym: "increased spore volume" EXACT [PomBase:mah] synonym: "large spore" RELATED [PomBase:vw] is_a: FYPO:0000025 ! swollen cell is_a: FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2011-07-07T03:34:09Z [Term] id: FYPO:0000348 name: abnormal spore morphology def: "A cell phenotype characterized by altered spore morphology, i.e. the size, shape, or structure of the spore is abnormal." [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2011-07-07T03:35:26Z [Term] id: FYPO:0000349 name: abnormal Golgi morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the Golgi apparatus is abnormal." [PomBase:mah] comment: Note that an abnormal Golgi organization process may, but does not necessarily, result in abnormal Golgi morphology. synonym: "abnormal Golgi morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal Golgi morphology during vegetative growth" EXACT [PomBase:mah] synonym: "Golgi morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000353 ! abnormal endomembrane system morphology relationship: output_of FYPO:0000806 ! abnormal Golgi organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000350 name: abnormal actin cytoskeleton morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actin cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in abnormal actin cytoskeleton morphology. synonym: "abnormal actin cytoskeleton morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cytoskeleton morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000352 ! abnormal cytoskeleton morphology during vegetative growth is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000351 name: abnormal cell wall morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type cell wall is abnormal." [PomBase:mah] synonym: "abnormal cell wall morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell wall morphology: abnormal during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000027 ! abnormal cell wall during vegetative growth is_a: FYPO:0002947 ! abnormal cell wall morphology created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000352 name: abnormal cytoskeleton morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in abnormal cytoskeleton morphology. synonym: "abnormal cytoskeleton morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoskeleton morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0003063 ! abnormal cytoskeleton morphology created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000353 name: abnormal endomembrane system morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the endomembrane system is abnormal." [PomBase:mah] comment: Note that an abnormal endomembrane system organization process may, but does not necessarily, result in abnormal endomembrane system morphology. synonym: "abnormal endomembrane system morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal endomembrane system morphology during vegetative growth" EXACT [PomBase:mah] synonym: "endomembrane system morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002404 ! abnormal endomembrane system relationship: output_of FYPO:0000804 ! abnormal endomembrane system organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000354 name: abnormal endoplasmic reticulum morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the endoplasmic reticulum is abnormal." [PomBase:mah] comment: Note that an abnormal endoplasmic reticulum organization process may, but does not necessarily, result in abnormal endoplasmic reticulum morphology. synonym: "abnormal endoplasmic reticulum morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal endoplasmic reticulum morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ER morphology" EXACT [PomBase:mah] synonym: "endoplasmic reticulum morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000353 ! abnormal endomembrane system morphology relationship: output_of FYPO:0000805 ! abnormal endoplasmic reticulum organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000355 name: normal endoplasmic reticulum morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the endoplasmic reticulum is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "endoplasmic reticulum morphology: normal" RELATED [SGD:phenotype_annotation] synonym: "normal endoplasmic reticulum morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal endoplasmic reticulum morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal ER morphology" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000356 name: abnormal lipid droplet morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of lipid droplets is abnormal." [PomBase:mah] comment: Note that an abnormal lipid droplet organization process may, but does not necessarily, result in abnormal lipid droplet morphology. synonym: "abnormal lipid droplet morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal lipid droplet morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal lipid particle morphology" EXACT [GO:0005811] synonym: "lipid particle morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0000808 ! abnormal lipid droplet organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000357 name: abnormal shmoo morphology def: "A physical cellular phenotype in which the size, shape, or structure of the mating projection is abnormal." [PomBase:mah] synonym: "abnormal conjugation tube morphology" EXACT [PomBase:mah] synonym: "abnormal mating projection morphology" EXACT [PomBase:mah] synonym: "mating projection morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000287 ! abnormal subcellular component relationship: output_of FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000358 name: shmoo absent def: "A physical cellular phenotype in which cells do not form mating projections." [PomBase:mah] synonym: "absent mating projection morphology" EXACT [PomBase:mah] synonym: "mating projection absent" EXACT [PomBase:mah] synonym: "mating projection morphology: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000359 name: abnormal mitochondrial morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitochondrion is abnormal." [PomBase:mah] comment: Note that an abnormal mitochondrion organization process may, but does not necessarily, result in abnormal mitochondrial morphology. synonym: "abnormal mitochondrial morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial morphology during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0004943 ! abnormal mitochondrion relationship: output_of FYPO:0000809 ! abnormal mitochondrion organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000360 name: abnormal RNA localization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA localization is abnormal." [PomBase:mah] synonym: "abnormal RNA localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNA localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA localization: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0003057 ! abnormal RNA localization created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000361 name: abnormal nucleolar morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the nucleolus is abnormal." [PomBase:mah] comment: Note that an abnormal nucleolus organization process may, but does not necessarily, result in abnormal nucleolar morphology. synonym: "abnormal nucleolar morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleolar morphology during vegetative growth" EXACT [PomBase:mah] synonym: "nucleolar morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0000814 ! abnormal nucleolus organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000362 name: abnormal peroxisomal morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the peroxisome is abnormal." [PomBase:mah] comment: Note that an abnormal peroxisome organization process may, but does not necessarily, result in abnormal peroxisome morphology. synonym: "abnormal peroxisomal morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal peroxisomal morphology during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0000811 ! abnormal peroxisome organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000363 name: peroxisomes absent def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain peroxisomes." [PomBase:mah] synonym: "absent peroxisomal morphology" EXACT [PomBase:mah] synonym: "peroxisomal morphology: absent" RELATED [SGD:phenotype_annotation] synonym: "peroxisomes absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "peroxisomes absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000364 name: abnormal plasma membrane morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the plasma membrane is abnormal." [PomBase:mah] comment: Note that an abnormal plasma membrane organization process may, but does not necessarily, result in abnormal plasma membrane morphology. synonym: "abnormal plasma membrane morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "plasma membrane morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000365 name: small nucleus def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is smaller than normal." [PomBase:mah] comment: Consider also annotating to 'decreased nucleus:cytoplasm ratio' (FYPO:0006927). synonym: "size of nucleus: decreased" RELATED [SGD:phenotype_annotation] synonym: "small nuclei" EXACT [PomBase:vw] synonym: "small nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000366 name: decreased RNA localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA localization is decreased." [PomBase:mah] synonym: "decreased RNA localisation" EXACT [PomBase:mah] synonym: "decreased RNA localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA localization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA localization" EXACT [PomBase:mah] synonym: "RNA localization: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000360 ! abnormal RNA localization during vegetative growth created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000368 name: abnormal vacuolar morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type vacuole is abnormal." [PomBase:mah] comment: Note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuolar morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal vacuole morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002257 ! abnormal vacuolar morphology is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth relationship: output_of FYPO:0000812 ! abnormal vacuole organization during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000369 name: vacuoles absent def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain vacuoles." [PomBase:mah] synonym: "absent vacuolar morphology" EXACT [PomBase:mah] synonym: "vacuolar morphology: absent" RELATED [SGD:phenotype_annotation] synonym: "vacuoles absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vacuoles absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000370 name: abnormal RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA modification is abnormal. All RNA modification may be abnormal, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "abnormal RNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "RNA modification: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000371 name: abolished RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA modification does not occur. All RNA modification may be abolished, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "abolished RNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent RNA modification" EXACT [PomBase:mah] synonym: "RNA modification abolished" EXACT [PomBase:mah] synonym: "RNA modification abolished during vegetative growth" EXACT [PomBase:mah] synonym: "RNA modification: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000372 name: decreased RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA modification is decreased. All RNA modification may be decreased, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "decreased RNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA modification" EXACT [PomBase:mah] synonym: "RNA modification: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000373 name: decreased rate of RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of RNA modification is decreased." [PomBase:mah] synonym: "decreased rate of RNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of RNA modification" EXACT [PomBase:mah] synonym: "RNA modification: decreased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000374 name: increased RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA modification is increased. All RNA modification may be increased, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "increased RNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "RNA modification: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000375 name: abolished apoptotic process def: "A cellular process phenotype in which programmed cell death by apoptosis does not occur. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "abolished apoptosis" NARROW [GO:0006915] synonym: "absent apoptotic process" EXACT [PomBase:mah] synonym: "apoptosis: absent" RELATED [SGD:phenotype_annotation] synonym: "apoptotic process abolished" EXACT [PomBase:mah] is_a: FYPO:0000629 ! abnormal apoptotic process created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000376 name: decreased frequency of apoptosis def: "A cell population phenotype in which the frequency of occurrence of apoptosis is decreased. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "apoptosis: decreased" RELATED [SGD:phenotype_annotation] synonym: "decreased apoptosis" EXACT [PomBase:mah] synonym: "decreased apoptotic frequency" EXACT [PomBase:mah] synonym: "reduced frequency of apoptosis" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000377 name: increased frequency of apoptosis def: "A cell population phenotype in which the frequency of occurrence of apoptosis is increased. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "apoptosis: increased" RELATED [SGD:phenotype_annotation] synonym: "increased apoptosis" EXACT [PomBase:mah] synonym: "increased apoptotic frequency" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000378 name: normal apoptosis def: "A cellular process phenotype in which apoptosis is normal (i.e. indistinguishable from wild type). Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "apoptosis: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000380 name: abolished macroautophagy def: "A cellular process phenotype in which macroautophagy does not occur." [PomBase:mah] synonym: "abolished autophagy" BROAD [PomBase:mah] synonym: "absent macroautophagy" EXACT [PomBase:mah] synonym: "autophagy: absent" BROAD [SGD:phenotype_annotation] synonym: "macroautophagy abolished" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal macroautophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000381 name: decreased macroautophagy def: "A cellular process phenotype in which the occurrence of macroautophagy is decreased." [PomBase:mah] synonym: "autophagy: decreased" BROAD [SGD:phenotype_annotation] synonym: "decreased autophagy" BROAD [PomBase:mah] synonym: "reduced macroautophagy" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal macroautophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000382 name: decreased rate of macroautophagy def: "A cellular process phenotype in which the rate, or speed, of macroautophagy is decreased." [PomBase:mah] synonym: "autophagy: decreased rate" BROAD [SGD:phenotype_annotation] synonym: "decreased rate of autophagy" BROAD [PomBase:mah] synonym: "reduced rate of macroautophagy" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal macroautophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000383 name: delayed onset of macroautophagy def: "A cellular process phenotype in which macroautophagy begins later than normal." [PomBase:mah] synonym: "autophagy: delayed" BROAD [SGD:phenotype_annotation] synonym: "delayed macroautophagy" EXACT [PomBase:mah] synonym: "delayed onset of autophagy" BROAD [PomBase:mah] is_a: FYPO:0000163 ! abnormal macroautophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000384 name: increased macroautophagy def: "A cellular process phenotype in which the occurrence of macroautophagy is increased." [PomBase:mah] synonym: "autophagy: increased" BROAD [SGD:phenotype_annotation] is_a: FYPO:0000163 ! abnormal macroautophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000385 name: normal macroautophagy def: "A cellular process phenotype in which macroautophagy is normal (i.e. indistinguishable from wild type). Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm." [PomBase:mah] synonym: "autophagy: normal" BROAD [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000386 name: abolished biofilm formation def: "A cellular process phenotype in which biofilm formation does not occur." [PomBase:mah] synonym: "absent biofilm formation" EXACT [PomBase:mah] synonym: "biofilm formation abolished" EXACT [PomBase:mah] synonym: "biofilm formation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000630 ! abnormal biofilm formation created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000387 name: decreased biofilm formation def: "A cellular process phenotype in which the occurrence of biofilm formation is decreased." [PomBase:mah] synonym: "biofilm formation: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced biofilm formation" EXACT [PomBase:mah] is_a: FYPO:0000630 ! abnormal biofilm formation created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000388 name: increased biofilm formation def: "A cellular process phenotype in which the occurrence of biofilm formation is increased." [PomBase:mah] synonym: "biofilm formation: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000630 ! abnormal biofilm formation created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000389 name: cell cycle arrest at mitotic START def: "A cellular process phenotype in which traversing the start control point of the mitotic cell cycle is arrested." [PomBase:mah] synonym: "cell cycle arrest at mitotic START during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle arrest at START during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle passage through START: arrested" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle arrest at START" EXACT [PomBase:mah] is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000390 name: premature passage through START of mitotic cell cycle def: "A cellular process phenotype in which traversing the start control point of the mitotic cell cycle begins earlier than normal." [PomBase:mah] synonym: "advanced passage through START of mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle passage through START: increased rate" RELATED [SGD:phenotype_annotation] synonym: "premature mitotic cell cycle passage through START" EXACT [PomBase:mah] synonym: "premature passage through START of mitotic cell cycle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0000827 ! premature cell cycle phase transition created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000391 name: normal passage through START of mitotic cell cycle def: "A cellular process phenotype in which traversing the start control point of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "cell cycle passage through START: normal" RELATED [SGD:phenotype_annotation] synonym: "normal mitotic cell cycle passage through START" EXACT [PomBase:mah] synonym: "normal passage through START of mitotic cell cycle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000411 ! normal mitotic cell cycle created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000392 name: obsolete abnormal cell cycle arrest at mitotic metaphase/anaphase transition def: "OBSOLETE. A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the metaphase/anaphase transition under conditions where arrest does not normally occur." [PomBase:mah] comment: This term was made obsolete because the metaphase/anaphase transition is a single all-or-nothing switch that cannot be started and then stopped before completion. Use 'abnormal cell cycle arrest in mitotic metaphase' (FYPO:0000620). synonym: "abnormal cell cycle arrest at metaphase/anaphase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic metaphase/anaphase transition with condensed chromosomes" EXACT [PomBase:vw] synonym: "abnormal mitotic cell cycle arrest at metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic metaphase/anaphase arrest" EXACT [PomBase:mah] synonym: "cell cycle passage through the metaphase-anaphase transition: arrested" RELATED [SGD:phenotype_annotation] is_obsolete: true replaced_by: FYPO:0000620 created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000394 name: abnormal mitotic G1/S phase transition def: "A cellular process phenotype in which the G1/S transition of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal cell cycle progression through the G1/S phase transition" EXACT [PomBase:mah] synonym: "abnormal G1/S phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle G1/S phase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic G1/S cell cycle phase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000397 name: obsolete decreased duration of mitotic G1/S phase transition def: "OBSOLETE. A cellular process phenotype in which the duration of progression through the G1/S transition of the mitotic cell cycle is shorter than normal." [PomBase:mah] comment: This term was made obsolete because a cell cycle transition is a time point, rather than a stage or phase that can have a duration. synonym: "cell cycle progression through the G1/S phase transition: increased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased duration of cell cycle progression through mitotic G1/S phase transition" EXACT [PomBase:mah] synonym: "decreased duration of mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of cell cycle progression through mitotic G1/S phase transition" RELATED [PomBase:mah] synonym: "reduced duration of mitotic G1/S phase transition" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000398 name: premature mitotic G1/S phase transition def: "A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle begins earlier than normal." [PomBase:mah] synonym: "advanced mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: premature" RELATED [SGD:phenotype_annotation] synonym: "premature cell cycle progression through mitotic G1/S phase transition" EXACT [PomBase:mah] synonym: "premature G1/S phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic G1/S transition" EXACT [PomBase:mah] is_a: FYPO:0000394 ! abnormal mitotic G1/S phase transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000399 name: abnormal mitotic G2/M phase transition def: "A cellular process phenotype in which the G2/M transition of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "abnormal cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle G2/M phase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic G2/M cell cycle phase transition" EXACT [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000400 name: abnormal cell cycle arrest at mitotic G2/M phase transition alt_id: FYPO:0003373 def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the G2/M transition, under conditions where arrest is not a normal occurrence." [PomBase:mah] comment: Use this term for terminal arrest. If arrest is transient, consider using 'mitotic G2/M transition delay' (FYPO:0000012). synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest at G2/M phase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic G2/M phase arrest" EXACT [PomBase:mah] synonym: "abolished mitotic G2/M phase transition" RELATED [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000446 ! cell cycle arrest at mitotic G2/M phase transition is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000402 name: increased mitotic G2/M phase transition def: "A cellular process phenotype in which the occurrence of progression through the G2/M transition of the mitotic cell cycle is increased." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: increased" RELATED [SGD:phenotype_annotation] synonym: "increased cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "increased G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased occurrence of mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal mitotic G2/M phase transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000403 name: obsolete increased duration of mitotic G2/M phase transition def: "OBSOLETE. A cellular process phenotype in which the duration of progression through the G2/M transition of the mitotic cell cycle is increased." [PomBase:mah] comment: This term was made obsolete because a cell cycle transition is a time point, rather than a stage or phase that can have a duration. synonym: "cell cycle progression through the G2/M phase transition: increased duration" RELATED [SGD:phenotype_annotation] synonym: "increased duration of cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "increased duration of mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000404 name: obsolete decreased duration of mitotic G2/M phase transition def: "OBSOLETE. A cellular process phenotype in which the duration of progression through the G2/M transition of the mitotic cell cycle is shorter than normal." [PomBase:mah] comment: This term was made obsolete because a cell cycle transition is a time point, rather than a stage or phase that can have a duration. synonym: "cell cycle progression through the G2/M phase transition: increased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased duration of cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "decreased duration of cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of mitotic G2/M phase transition" RELATED [PomBase:mah] synonym: "reduced duration of mitotic G2/M phase transition" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000405 name: normal mitotic G2/M phase transition def: "A cellular process phenotype in which the G2/M transition of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: normal" RELATED [SGD:phenotype_annotation] synonym: "normal cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "normal G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002741 ! normal mitotic cell cycle process created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000407 name: abnormally arrested cell cycle progression def: "A cellular process phenotype in which cell cycle progression is arrested under conditions where arrest does not normally occur." [PomBase:mah] comment: Note that this term should be used only for cell cycle arrest that occurs in mutants but not in wild type cells. For phenotypes affecting cell cycle that normally occurs, e.g. in response to mating pheromone, see 'normally arrested mitotic cell cycle progression' (FYPO:0001025), 'abnormal occurrence of normal mitotic cell cycle arrest' (FYPO:0001026), and their child terms. synonym: "abnormal cell cycle arrest" EXACT [PomBase:mah] synonym: "abnormally arrested cell cycle progression during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormally arrested cell cycle progression during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001024 ! cell cycle arrest phenotype is_a: FYPO:0002734 ! abnormal cell cycle process created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000408 name: increased duration of cell cycle phase def: "A cellular process phenotype in which the duration of one or more cell cycle phases is longer than normal." [PomBase:mah] synonym: "cell cycle progression: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased rate of cell cycle progression" RELATED [PomBase:mah] synonym: "prolonged cell cycle phase" EXACT [PomBase:mah] synonym: "reduced rate of cell cycle progression" RELATED [PomBase:mah] is_a: FYPO:0002735 ! abnormal cell cycle phase created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000409 name: delayed cell cycle phase transition def: "A cellular process phenotype in which one or more cell cycle phase transitions begins later than normal." [PomBase:mah] synonym: "cell cycle progression: delayed" RELATED [SGD:phenotype_annotation] synonym: "delayed cell cycle phase transition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed cell cycle phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0005273 ! abnormal cell cycle phase transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000410 name: decreased duration of cell cycle phase def: "A cellular process phenotype in which the duration of one or more cell cycle phases is shorter than normal." [PomBase:mah] synonym: "cell cycle progression: increased rate" RELATED [SGD:phenotype_annotation] synonym: "increased rate of cell cycle progression" RELATED [PomBase:mah] synonym: "reduced duration of cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0002735 ! abnormal cell cycle phase created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000411 name: normal mitotic cell cycle def: "A cellular process phenotype in which mitotic cell cycle progression is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitotic cell cycle progression: normal" RELATED [SGD:phenotype_annotation] synonym: "normal cell cycle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell cycle during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle progression" EXACT [PomBase:mah] synonym: "normal mitotic cell-division cycle" EXACT [GO:0007049, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0003832 ! normal cell cycle created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000412 name: abnormal cell fusion during mating def: "A cellular process phenotype in which plasma membrane fusion involved in cytogamy is abnormal." [PomBase:mah] synonym: "abnormal cell fusion during conjugation" EXACT [PomBase:mah] synonym: "abnormal plasma membrane fusion involved in cytogamy" EXACT [GO:0032220] synonym: "cell fusion: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000413 name: abolished cell fusion during mating def: "A cellular process phenotype in which plasma membrane fusion involved in cytogamy does not occur." [PomBase:mah] synonym: "abolished cell fusion during conjugation" EXACT [PomBase:mah] synonym: "abolished plasma membrane fusion involved in cytogamy" EXACT [GO:0032220] synonym: "absent cell fusion during mating" EXACT [PomBase:mah] synonym: "cell fusion abolished during mating" EXACT [PomBase:mah] synonym: "cell fusion: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000412 ! abnormal cell fusion during mating created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000414 name: obsolete decreased cell fusion during mating def: "OBSOLETE. A cellular process phenotype in which plasma membrane fusion involved in cytogamy is decreased." [PomBase:mah] comment: This term was previously used to indicate defects in cell fusion that led to lower frequencies of cell fusion in mating pairs (cells that have touched each other with shmoo) than in wild-type, where it is essentially 100%. Since cell fusion is a yes / no phenotype, and wild-type is 100%, these annotations can be moved to abolished cell fusion with a certain penetrance. synonym: "cell fusion: decreased" RELATED [SGD:phenotype_annotation] synonym: "decreased cell fusion during conjugation" EXACT [PomBase:mah] synonym: "decreased plasma membrane fusion involved in cytogamy" EXACT [GO:0032220] synonym: "reduced cell fusion during mating" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0000413 created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000415 name: decreased mitotic sister chromatid segregation def: "A cellular process phenotype in which the occurrence of mitotic sister chromatid segregation is decreased." [PomBase:mah] synonym: "chromosome segregation: decreased" BROAD [SGD:phenotype_annotation] synonym: "decreased chromosome segregation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic chromosome segregation" EXACT [GO:0000070] synonym: "decreased sister chromatid segregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced mitotic sister chromatid segregation" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000416 name: premature mitotic sister chromatid separation def: "A cellular process phenotype in which mitotic sister chromatid separation begins before anaphase." [PomBase:mah] synonym: "advanced mitotic sister chromatid separation" EXACT [PomBase:mah] synonym: "chromosome segregation: premature" BROAD [SGD:phenotype_annotation] synonym: "premature chromosome separation during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic chromosome separation" EXACT [GO:0051306] synonym: "premature sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000417 name: abolished cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic cytokinesis does not occur." [PomBase:mah] synonym: "abolished cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent cytokinesis" EXACT [PomBase:mah] synonym: "cytokinesis abolished" EXACT [PomBase:mah] synonym: "cytokinesis abolished during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinesis: absent" RELATED [SGD:phenotype_annotation] synonym: "mitotic cytokinesis abolished" EXACT [GO:0000281, PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000418 name: decreased cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitotic cytokinesis is decreased." [PomBase:mah] synonym: "cytokinesis: decreased" RELATED [SGD:phenotype_annotation] synonym: "decreased cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic cytokinesis" EXACT [GO:0000281, PomBase:mah] synonym: "reduced cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000419 name: decreased rate of cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic cytokinesis is decreased." [PomBase:mah] synonym: "cytokinesis: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased rate of cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of mitotic cytokinesis" EXACT [GO:0000281, PomBase:mah] synonym: "reduced rate of cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000420 name: delayed onset of cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic cytokinesis begins later than normal." [PomBase:mah] synonym: "cytokinesis: delayed" RELATED [SGD:phenotype_annotation] synonym: "delayed cytokinesis" EXACT [PomBase:mah] synonym: "delayed onset of cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitotic cytokinesis" EXACT [GO:0000281, PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000421 name: abolished endocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis does not occur. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "abolished actin-mediated endocytosis during vegetative growth" EXACT [PomBase:vw] synonym: "abolished endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein internalization during vegetative growth" NARROW [PomBase:vw] synonym: "absent endocytosis during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis abolished during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis: absent during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth relationship: has_output FYPO:0003504 ! increased protein level in plasma membrane created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000422 name: decreased endocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of endocytosis is decreased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "decreased endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein internalization during vegetative growth" NARROW [PomBase:vw] synonym: "endocytosis: decreased during vegetative growth" RELATED [SGD:phenotype_annotation] synonym: "reduced actin-mediated endocytosis during vegetative growth" EXACT [PomBase:vw] synonym: "reduced endocytosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth relationship: has_output FYPO:0003504 ! increased protein level in plasma membrane created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000423 name: decreased rate of endocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of endocytosis is decreased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "decreased rate of actin-mediated endocytosis during vegetative growth" EXACT [PomBase:vw] synonym: "decreased rate of endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of protein internalization during vegetative growth" NARROW [PomBase:vw] synonym: "endocytosis: decreased rate during vegetative growth" RELATED [SGD:phenotype_annotation] synonym: "reduced rate of endocytosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000424 name: delayed onset of endocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis begins later than normal. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "delayed endocytosis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of actin-mediated endocytosis during vegetative growth" EXACT [PomBase:vw] synonym: "delayed onset of endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein internalization during vegetative growth" NARROW [PomBase:vw] synonym: "endocytosis: delayed during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000425 name: increased endocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of endocytosis is increased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "endocytosis: increased during vegetative growth" RELATED [SGD:phenotype_annotation] synonym: "increased actin-mediated endocytosis during vegetative growth" EXACT [PomBase:vw] synonym: "increased endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein internalization during vegetative growth" NARROW [PomBase:vw] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000426 name: normal endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "endocytosis: normal" RELATED [SGD:phenotype_annotation] synonym: "normal endocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal endocytosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000427 name: abnormal G1 to G0 transition def: "A cellular process phenotype in which the G1 to G0 transition is abnormal." [PomBase:mah] synonym: "abnormal cell cycle quiescence" RELATED [GO:0070314, PomBase:mah] synonym: "abnormal establishment of cell quiescence" EXACT [GO:0070314, PomBase:mah] synonym: "abnormal G1/G0 transition" EXACT [GO:0070314, PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000428 name: abolished entry into G0 def: "A cellular process phenotype in which the G1 to G0 transition does not occur." [PomBase:mah] synonym: "cell cycle quiescence abolished" RELATED [GO:0070314, PomBase:mah] synonym: "entry into G0 abolished" EXACT [PomBase:mah] synonym: "establishment of cell quiescence abolished" EXACT [GO:0070314, PomBase:mah] synonym: "G1/G0 transition abolished" EXACT [GO:0070314, PomBase:mah] is_a: FYPO:0000427 ! abnormal G1 to G0 transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000429 name: delayed G0 to G1 transition def: "A cellular process phenotype in which the G0 to G1 transition begins later than normal." [PomBase:mah] synonym: "delayed exit from cell quiescence" EXACT [PomBase:vw] synonym: "delayed exit from G0" EXACT [PomBase:vw] synonym: "delayed G0/G1 transition" EXACT [PomBase:mah] synonym: "slow cell population growth following nitrogen starvation" RELATED [PomBase:al] is_a: FYPO:0002955 ! abnormal G0 to G1 transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000430 name: abnormal fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation is abnormal." [PomBase:mah] synonym: "abnormal fermentation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal fermentative metabolism" EXACT [PomBase:mah] synonym: "fermentative metabolism: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000431 name: abolished fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation does not occur." [PomBase:mah] synonym: "abolished fermentation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent fermentative metabolism" EXACT [PomBase:mah] synonym: "fermentation abolished" EXACT [PomBase:mah] synonym: "fermentation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "fermentative metabolism abolished" EXACT [PomBase:mah] synonym: "fermentative metabolism: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000430 ! abnormal fermentation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000432 name: decreased fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of fermentation is decreased." [PomBase:mah] synonym: "decreased fermentation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased fermentative metabolism" EXACT [PomBase:mah] synonym: "fermentative metabolism: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced fermentation" EXACT [PomBase:mah] is_a: FYPO:0000430 ! abnormal fermentation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000433 name: increased fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of fermentation is increased." [PomBase:mah] synonym: "fermentative metabolism: increased" RELATED [SGD:phenotype_annotation] synonym: "increased fermentation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "increased fermentative metabolism" EXACT [PomBase:mah] is_a: FYPO:0000430 ! abnormal fermentation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000434 name: normal fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "fermentative metabolism: normal" RELATED [SGD:phenotype_annotation] synonym: "normal fermentation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "normal fermentative metabolism" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000440 name: sensitive to antimycin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to antimycin A. Cells stop growing (and may die) at a concentration of antimycin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to antimycin A" EXACT [PomBase:mah] synonym: "sensitive to antimycin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to antimycin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-08-03T04:41:43Z [Term] id: FYPO:0000441 name: resistance to antimycin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of antimycin than normal." [PomBase:mah] synonym: "resistance to antimycin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to antimycin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to antimycin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-08-03T04:41:43Z [Term] id: FYPO:0000442 name: decreased cell population growth on glycerol/ethanol carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol and ethanol as the carbon sources." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased cell growth on glycerol plus ethanol" EXACT [PomBase:mah] synonym: "decreased growth on glycerol/ethanol carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on glycerol/ethanol carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on glycerol/ethanol carbon source" RELATED [PomBase:mah] synonym: "slow cell growth on glycerol/ethanol carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-08-03T05:18:32Z [Term] id: FYPO:0000443 name: abnormal protein localization during vegetative growth def: "A cell phenotype that affects the localization of a protein in a cell in the vegetative growth phase of the life cycle. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abnormal cellular protein localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein/peptide distribution: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2011-08-04T04:19:46Z [Term] id: FYPO:0000444 name: abnormal mitotic cell cycle arrest with replicated DNA def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have replicated genomic DNA, under conditions where arrest does not normally occur." [PomBase:mah] comment: Arrest with replicated DNA may occur between late S and G2/M; if only DNA content is measured, the arrest point cannot be determined with greater precision. synonym: "abnormal cell cycle arrest with replicated DNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with 2C DNA content" NARROW [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with replicated DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression created_by: midori creation_date: 2011-08-12T02:03:05Z [Term] id: FYPO:0000445 name: cell cycle arrest in mitotic G1 phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G1 phase." [PomBase:mah] comment: For phenotypes affecting the G1 cell cycle that normally occurs in response to mating pheromone, see 'abnormal cell cycle arrest in response to pheromone' (FYPO:0000530) and its child terms. synonym: "cell cycle arrest in G1 phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle arrest in mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in G1 phase" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: arrested" RELATED [SGD:phenotype_annotation] synonym: "mitotic G1 phase arrest" EXACT [PomBase:mah] is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-08-12T02:07:59Z [Term] id: FYPO:0000446 name: cell cycle arrest at mitotic G2/M phase transition def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition." [PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle arrest in mitotic G2 phase" RELATED [PomBase:mah] synonym: "mitotic cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression at mitotic G2/M phase transition: arrested" RELATED [SGD:phenotype_annotation] synonym: "mitotic G2 phase arrest" RELATED [PomBase:mah] synonym: "mitotic G2/M phase transition arrest" EXACT [PomBase:mah] is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-08-12T02:11:06Z [Term] id: FYPO:0000447 name: abnormal protein-containing complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of protein complex assembly at the cellular level is abnormal." [PomBase:mah] synonym: "abnormal protein complex assembly" NARROW [GO:0034622] synonym: "abnormal protein complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2011-08-12T02:26:26Z [Term] id: FYPO:0000448 name: abnormal MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is abnormal." [PomBase:mah] synonym: "abnormal MCM complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal MCM complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2011-08-12T02:27:22Z [Term] id: FYPO:0000449 name: abnormal protein localization to centromere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the centromere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localisation to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to chromosome, centric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0005597 ! abnormal protein localization to centromere created_by: midori creation_date: 2011-08-12T02:29:38Z [Term] id: FYPO:0000450 name: decreased protein localization to centromere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localisation to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromosome, centric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "reduced protein localization to centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0006238 ! decreased protein localization to centromere created_by: midori creation_date: 2011-08-12T02:33:53Z [Term] id: FYPO:0000451 name: increased protein localization to centromere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localisation to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromosome, centric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0006239 ! increased protein localization to centromere created_by: midori creation_date: 2011-08-12T02:34:10Z [Term] id: FYPO:0000452 name: abnormal protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromatin during vegetative growth" EXACT [GO:0071168, PomBase:mah] synonym: "abnormal protein localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001679 ! abnormal protein localization to chromatin created_by: midori creation_date: 2011-08-12T02:35:06Z [Term] id: FYPO:0000453 name: DNA content decreased during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of DNA in a cell is lower than normal." [PomBase:mah] synonym: "decreased DNA content during vegetative growth" EXACT [PomBase:mah] synonym: "decreased DNA level during vegetative growth" EXACT [PomBase:mah] synonym: "DNA content decreased during mitotic cell cycle" RELATED [PomBase:mah] synonym: "DNA content reduced during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0004321 ! altered DNA level during vegetative growth created_by: midori creation_date: 2011-08-12T02:37:29Z [Term] id: FYPO:0000454 name: obsolete inviable mixed population including long and short cells def: "OBSOLETE. A mixed population phenotype in which a microcolony forms, all cells in the population are inviable, and some cells are longer and other cells smaller than normal." [PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including long and short vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-08-12T02:39:05Z [Term] id: FYPO:0000455 name: increased number of double-strand break sites during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of double-strand breaks in DNA is greater than normal." [PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad52 foci during vegetative growth' (FYPO:0000972). synonym: "accumulation of DNA damage foci during vegetative growth" RELATED [PomBase:mah] synonym: "accumulation of double-strand break sites during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of DNA damage foci during vegetative growth" RELATED [PomBase:mah] synonym: "increased number of double-strand break sites during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0003543 ! increased number of double-strand break sites is_a: FYPO:0003547 ! increased DNA damage during vegetative growth created_by: midori creation_date: 2011-08-12T02:44:35Z [Term] id: FYPO:0000456 name: abnormal histone acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation is abnormal." [PomBase:mah] synonym: "abnormal histone acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification during vegetative growth created_by: midori creation_date: 2011-08-12T02:55:54Z [Term] id: FYPO:0000457 name: abnormal histone methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered." [PomBase:mah] synonym: "abnormal histone methylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification during vegetative growth is_a: FYPO:0006870 ! abnormal histone methylation created_by: midori creation_date: 2011-08-12T02:56:38Z [Term] id: FYPO:0000458 name: abnormal histone H3-K9 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abnormal histone H3-K9 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K9me during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abnormal histone lysine H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth is_a: FYPO:0007466 ! abnormal histone H3-K9 methylation created_by: midori creation_date: 2011-08-12T02:57:59Z [Term] id: FYPO:0000459 name: abnormal mitotic centromeric sister chromatid cohesion def: "A cellular process phenotype in which cohesion between centromeres of sister chromatids is abnormal during mitosis." [PomBase:mah] synonym: "abnormal centromeric sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal centromeric sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid cohesion at centromere" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid cohesion, centromeric" EXACT [GO:0071962, PomBase:mah] synonym: "abnormal sister chromatid cohesion at centromere during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-08-12T03:12:26Z [Term] id: FYPO:0000460 name: decreased mitotic centromeric sister chromatid cohesion def: "A cellular process phenotype in which cohesion between centromeres of sister chromatids is decreased during mitosis." [PomBase:mah] synonym: "decreased centromeric sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased centromeric sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic sister chromatid cohesion at centromere" EXACT [PomBase:mah] synonym: "decreased mitotic sister chromatid cohesion, centromeric" EXACT [GO:0071962, PomBase:mah] synonym: "decreased sister chromatid cohesion at centromere during mitosis" EXACT [PomBase:mah] synonym: "reduced mitotic centromeric sister chromatid cohesion" EXACT [PomBase:mah] is_a: FYPO:0000459 ! abnormal mitotic centromeric sister chromatid cohesion created_by: midori creation_date: 2011-08-12T03:14:23Z [Term] id: FYPO:0000461 name: obsolete flocculation abolished def: "OBSOLETE. A cellular process phenotype in which flocculation does not occur." [PomBase:mah] synonym: "absent flocculation" EXACT [PomBase:mah] synonym: "flocculation: absent" RELATED [SGD:phenotype_annotation] is_obsolete: true created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000463 name: obsolete normal flocculation def: "OBSOLETE. A cellular process phenotype in which flocculation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "flocculation: normal" RELATED [SGD:phenotype_annotation] is_obsolete: true created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000464 name: decreased intracellular transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of intracellular transport is decreased." [PomBase:mah] synonym: "decreased intracellular transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased intracellular transport during vegetative growth" EXACT [PomBase:mah] synonym: "intracellular transport: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced intracellular transport" EXACT [PomBase:mah] is_a: FYPO:0005973 ! abnormal transport during vegetative growth created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000466 name: obsolete decreased invasive growth def: "OBSOLETE. A cellular process phenotype in which the occurrence of invasive growth is decreased." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "invasive growth: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced invasive growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0000552 created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000467 name: obsolete increased invasive growth def: "OBSOLETE. A cellular process phenotype in which the occurrence of invasive growth is increased." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "invasive growth: increased" RELATED [SGD:phenotype_annotation] is_obsolete: true consider: FYPO:0000553 created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000468 name: abnormal mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching is abnormal." [PomBase:mah] synonym: "abnormal mating type switching during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mating type switching during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000469 name: abolished mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching does not occur." [PomBase:mah] synonym: "abolished mating type switching during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent mating type switching" EXACT [PomBase:mah] synonym: "mating type switching abolished" EXACT [PomBase:mah] synonym: "mating type switching abolished during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000470 name: decreased mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mating type switching is decreased." [PomBase:mah] synonym: "decreased mating type switching during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mating type switching during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mating type switching" EXACT [PomBase:mah] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000471 name: increased mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mating type switching is increased." [PomBase:mah] synonym: "increased mating type switching during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mating type switching during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000472 name: normal mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mating type switching: normal" RELATED [SGD:phenotype_annotation] synonym: "normal mating type switching during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mating type switching during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000473 name: increased mitotic recombination def: "A cellular process phenotype in which the occurrence of mitotic recombination is increased." [PomBase:mah] synonym: "increased mitotic recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000481 ! abnormal mitotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000474 name: abolished meiosis def: "A cellular process phenotype in which one or both meiotic nuclear division(s) does not occur." [PomBase:mah] synonym: "abolished meiotic nuclear division" EXACT [GO:0140013] synonym: "absent meiosis" EXACT [PomBase:mah] synonym: "meiosis abolished" EXACT [PomBase:mah] synonym: "meiosis: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000475 name: abnormally arrested meiosis def: "A cellular process phenotype in which one or both meiotic nuclear division(s) is arrested under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormally arrested meiotic nuclear division" EXACT [PomBase:mah] synonym: "meiosis: arrested" RELATED [SGD:phenotype_annotation] synonym: "meiotic cell cycle arrest in M phase" EXACT [PomBase:mah] is_a: FYPO:0002224 ! abnormally arrested meiotic cell cycle created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000476 name: decreased frequency of meiosis def: "A cell population phenotype in which the frequency of occurrence of one or both meiotic nuclear division(s) is decreased." [PomBase:mah] synonym: "decreased frequency of meiotic nuclear division" EXACT [GO:0140013] synonym: "decreased meiosis" EXACT [PomBase:mah] synonym: "meiosis: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced frequency of meiosis" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000477 name: delayed onset of meiosis def: "A cellular process phenotype in which one or both meiotic nuclear division(s) begins later than normal." [PomBase:mah] synonym: "delayed meiosis" EXACT [PomBase:mah] synonym: "delayed onset of meiotic nuclear division" EXACT [GO:0140013] synonym: "meiosis: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000478 name: normal meiosis def: "A cellular process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "meiosis: normal" RELATED [SGD:phenotype_annotation] synonym: "normal meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000479 name: premature meiosis def: "A cellular process phenotype in which one or both meiotic nuclear division(s) begins earlier than normal." [PomBase:mah] synonym: "advanced meiosis" EXACT [PomBase:mah] synonym: "meiosis: premature" RELATED [SGD:phenotype_annotation] synonym: "premature meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000481 name: abnormal mitotic recombination def: "A cellular process phenotype in which mitotic recombination is abnormal." [PomBase:mah] synonym: "abnormal mitotic recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000482 name: decreased mitotic recombination def: "A cellular process phenotype in which the occurrence of mitotic recombination is decreased." [PomBase:mah] synonym: "decreased mitotic recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mitotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000481 ! abnormal mitotic recombination is_a: FYPO:0002340 ! decreased DNA recombination during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000483 name: increased rate of mitotic recombination def: "A cellular process phenotype in which the rate, or speed, of mitotic recombination is increased." [PomBase:mah] synonym: "increased rate of mitotic recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000481 ! abnormal mitotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000484 name: abolished meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination does not occur." [PomBase:mah] synonym: "absent meiotic recombination" EXACT [PomBase:mah] synonym: "meiotic recombination abolished" EXACT [PomBase:mah] synonym: "meiotic recombination: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000485 name: decreased meiotic recombination def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is decreased." [PomBase:mah] synonym: "meiotic recombination: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced meiotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000486 name: delayed onset of meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination begins later than normal." [PomBase:mah] synonym: "delayed meiotic recombination" EXACT [PomBase:mah] synonym: "meiotic recombination: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000487 name: increased meiotic recombination def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is increased." [PomBase:mah] synonym: "meiotic recombination: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000488 name: normal meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "meiotic recombination: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000489 name: abnormal mitochondrial distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion distribution is abnormal." [PomBase:mah] synonym: "abnormal mitochondrial distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial distribution during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial distribution: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000490 name: abnormal mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance is abnormal." [PomBase:mah] synonym: "loss of mitochondrial DNA" NARROW [] synonym: "mitochondrial DNA depletion" NARROW [] synonym: "mitochondrial genome maintenance: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000491 name: abolished mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance does not occur." [PomBase:mah] synonym: "abolished mitochondrial genome maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent mitochondrial genome maintenance" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance abolished" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance abolished during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000490 ! abnormal mitochondrial genome maintenance created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000492 name: decreased mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial genome maintenance is decreased." [PomBase:mah] synonym: "decreased mitochondrial genome maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mitochondrial genome maintenance" EXACT [PomBase:mah] is_a: FYPO:0000490 ! abnormal mitochondrial genome maintenance created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000493 name: increased mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial genome maintenance is increased." [PomBase:mah] synonym: "increased mitochondrial genome maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000490 ! abnormal mitochondrial genome maintenance created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000494 name: normal mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitochondrial genome maintenance: normal" RELATED [SGD:phenotype_annotation] synonym: "normal mitochondrial genome maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000495 name: abnormal mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial transport is abnormal." [PomBase:mah] synonym: "abnormal mitochondrial transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial transport during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial transport: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000496 name: decreased mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial transport is decreased." [PomBase:mah] synonym: "decreased mitochondrial transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial transport during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial transport: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mitochondrial transport" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000495 ! abnormal mitochondrial transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000497 name: decreased rate of mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitochondrial transport is decreased." [PomBase:mah] synonym: "decreased rate of mitochondrial transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of mitochondrial transport during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial transport: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "reduced rate of mitochondrial transport" EXACT [PomBase:mah] is_a: FYPO:0000495 ! abnormal mitochondrial transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000498 name: normal mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitochondrial transport: normal" RELATED [SGD:phenotype_annotation] synonym: "normal mitochondrial transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000499 name: abolished mitophagy def: "A cellular process phenotype in which mitophagy does not occur." [PomBase:mah] synonym: "abolished autophagy of mitochondrion" EXACT [GO:0000422] synonym: "absent mitophagy" EXACT [PomBase:mah] synonym: "mitophagy abolished" EXACT [PomBase:mah] synonym: "mitophagy: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0007590 ! abnormal mitophagy created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000500 name: decreased mitophagy def: "A cellular process phenotype in which the occurrence of mitophagy is decreased." [PomBase:mah] synonym: "decreased autophagy of mitochondrion" EXACT [GO:0000422] synonym: "mitophagy: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mitophagy" EXACT [PomBase:mah] is_a: FYPO:0007590 ! abnormal mitophagy created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000501 name: increased mitophagy def: "A cellular process phenotype in which the occurrence of mitophagy is increased." [PomBase:mah] synonym: "increased autophagy of mitochondrion" EXACT [GO:0000422] synonym: "mitophagy: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0007590 ! abnormal mitophagy created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000502 name: abnormally arrested mitotic cell cycle progression def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest" RELATED [PomBase:mah] synonym: "abnormally arrested mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormally arrested mitotic cell cycle progression during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormally arrested mitotic cell cycle progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle abnormally arrested" EXACT [PomBase:mah] synonym: "mitotic cell cycle: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle is_a: FYPO:0000407 ! abnormally arrested cell cycle progression is_a: FYPO:0004040 ! mitotic cell cycle arrest phenotype created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000503 name: normal mitotic recombination def: "A cellular process phenotype in which mitotic recombination is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitotic recombination: normal" RELATED [SGD:phenotype_annotation] synonym: "normal mitotic recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic recombination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000504 name: obsolete decreased necrotic cell death def: "OBSOLETE. A cellular process phenotype in which the occurrence of necrotic cell death is decreased. Necrotic cell death is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [GO:0070265, PomBase:mah] comment: This term was made obsolete because necrotic cell death has not been observed in fission yeast. synonym: "necrotic cell death: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced necrotic cell death" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000505 name: obsolete increased necrotic cell death def: "OBSOLETE. A cellular process phenotype in which the occurrence of necrotic cell death is increased. Necrotic cell death is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [GO:0070265, PomBase:mah] comment: This term was made obsolete because necrotic cell death has not been observed in fission yeast. synonym: "necrotic cell death: increased" RELATED [SGD:phenotype_annotation] is_obsolete: true created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000506 name: abnormal nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export is abnormal. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abnormal nuclear export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear export during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000518 ! abnormal nuclear transport during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000507 name: abolished nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export does not occur. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abolished nuclear export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent nuclear export" EXACT [PomBase:mah] synonym: "nuclear export abolished" EXACT [PomBase:mah] synonym: "nuclear export abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000508 name: decreased nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of nuclear export is decreased. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "decreased nuclear export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nuclear export during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced nuclear export" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000509 name: normal nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export is normal (i.e. indistinguishable from wild type). Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "normal nuclear export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear export during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0008138 ! normal nucleocytoplasmic transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000510 name: abnormal nuclear fusion during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion is abnormal." [PomBase:mah] synonym: "abnormal karyogamy" EXACT [PomBase:mah] synonym: "abnormal karyogamy involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "abnormal nuclear fusion during conjugation" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000511 name: abolished nuclear fusion during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur." [PomBase:mah] synonym: "abolished nuclear fusion during conjugation" EXACT [PomBase:mah] synonym: "absent nuclear fusion during mating" EXACT [PomBase:mah] synonym: "karyogamy abolished" EXACT [PomBase:mah] synonym: "karyogamy involved in conjugation with cellular fusion abolished" EXACT [PomBase:mah] synonym: "nuclear fusion during mating abolished" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000510 ! abnormal nuclear fusion during mating created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000512 name: obsolete decreased nuclear fusion during mating def: "OBSOLETE. A cellular process phenotype in which the occurrence of karyogamy involved in conjugation with cellular fusion is decreased." [] comment: This term was made obsolete because nuclear fusion during mating cannot be decreased, it is an all or nothing event.\n Annotations arre transferred to the term 'abnormal nuclear fusion during mating' with \nthe appropriate penetrance property_value: seeAlso FYPO:0000511 is_obsolete: true [Term] id: FYPO:0000513 name: delayed onset of nuclear fusion during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion begins later than normal." [PomBase:mah] synonym: "delayed nuclear fusion during mating" EXACT [PomBase:mah] synonym: "delayed onset of karyogamy" EXACT [PomBase:mah] synonym: "delayed onset of karyogamy involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000510 ! abnormal nuclear fusion during mating created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000514 name: abolished nuclear import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear import does not occur. Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abolished nuclear import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent nuclear import" EXACT [PomBase:mah] synonym: "nuclear import abolished" EXACT [PomBase:mah] synonym: "nuclear import abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear import: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001217 ! abnormal nuclear import created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000515 name: decreased nuclear import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of nuclear import is decreased. Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "decreased nuclear import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nuclear import during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear import: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced nuclear import" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0001217 ! abnormal nuclear import created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000516 name: normal nuclear import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear import is normal (i.e. indistinguishable from wild type). Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "normal nuclear import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear import during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear import: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0008138 ! normal nucleocytoplasmic transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000517 name: abnormal nucleus positioning def: "A cellular process phenotype in which nucleus localization is abnormal." [PomBase:mah] synonym: "abnormal nuclear localization" EXACT [PomBase:mah] synonym: "abnormal nucleus localisation" EXACT [PomBase:mah] synonym: "abnormal nucleus localization" EXACT [] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000518 name: abnormal nuclear transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear transport is abnormal." [PomBase:mah] synonym: "abnormal nuclear transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear transport: abnormal during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0005573 ! abnormal nuclear transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000519 name: decreased oxidative phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidative phosphorylation is decreased." [PomBase:mah] synonym: "decreased oxidative phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased oxidative phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "oxidative phosphorylation: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced oxidative phosphorylation" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000520 name: increased oxidative phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidative phosphorylation is increased." [PomBase:mah] synonym: "increased oxidative phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased oxidative phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "oxidative phosphorylation: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000521 name: abnormal peroxisome localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome localization is abnormal." [PomBase:mah] synonym: "abnormal peroxisomal distribution" EXACT [PomBase:mah] synonym: "abnormal peroxisome localisation" EXACT [PomBase:mah] synonym: "abnormal peroxisome localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal peroxisome localization during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal distribution: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000522 name: abnormal peroxisomal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisomal transport is abnormal." [PomBase:mah] synonym: "abnormal peroxisomal transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal peroxisomal transport during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal transport: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000523 name: abolished peroxisomal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisomal transport does not occur." [PomBase:mah] synonym: "abolished peroxisomal transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent peroxisomal transport" EXACT [PomBase:mah] synonym: "peroxisomal transport abolished" EXACT [PomBase:mah] synonym: "peroxisomal transport abolished during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal transport: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000522 ! abnormal peroxisomal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000524 name: decreased peroxisomal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of peroxisomal transport is decreased." [PomBase:mah] synonym: "decreased peroxisomal transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased peroxisomal transport during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal transport: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced peroxisomal transport" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000522 ! abnormal peroxisomal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000525 name: abolished peroxisome degradation def: "A cellular process phenotype in which pexophagy does not occur." [PomBase:mah] synonym: "absent pexophagy" EXACT [PomBase:mah] synonym: "peroxisome degradation abolished" EXACT [PomBase:mah] synonym: "pexophagy abolished" EXACT [PomBase:mah] synonym: "pexophagy: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000526 name: decreased peroxisome degradation def: "A cellular process phenotype in which the occurrence of pexophagy is decreased." [PomBase:mah] synonym: "decreased pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced peroxisome degradation" EXACT [PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000527 name: decreased rate of peroxisome degradation def: "A cellular process phenotype in which the rate, or speed, of pexophagy is decreased." [PomBase:mah] synonym: "decreased rate of pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "reduced rate of peroxisome degradation" EXACT [PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000528 name: delayed onset of peroxisome degradation def: "A cellular process phenotype in which pexophagy begins later than normal." [PomBase:mah] synonym: "delayed onset of pexophagy" EXACT [PomBase:mah] synonym: "delayed peroxisome degradation" EXACT [PomBase:mah] synonym: "pexophagy: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000529 name: normal peroxisome degradation def: "A cellular process phenotype in which peroxisome degradation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002496 ! normal metabolic process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000530 name: abnormal mitotic cell cycle arrest in response to pheromone def: "A cellular process phenotype in which the mitotic cell cycle arrest that normally occurs in response to pheromone is abnormal." [PomBase:mah] synonym: "abnormal pheromone-induced mitotic cell cycle arrest" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000302 ! abnormal response to pheromone is_a: FYPO:0001026 ! abnormal occurrence of normal mitotic cell cycle arrest created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000531 name: abolished mitotic cell cycle arrest in response to pheromone def: "A cellular process phenotype in which mitotic cell cycle arrest in response to pheromone does not occur." [PomBase:mah] synonym: "absent pheromone-induced mitotic cell cycle arrest" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in response to pheromone abolished" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: absent" RELATED [SGD:phenotype_annotation] synonym: "pheromone-induced mitotic cell cycle arrest abolished" EXACT [PomBase:mah] is_a: FYPO:0000530 ! abnormal mitotic cell cycle arrest in response to pheromone created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000532 name: decreased mitotic cell cycle arrest in response to pheromone def: "A cellular process phenotype in which the occurrence of mitotic cell cycle arrest in response to pheromone is decreased." [PomBase:mah] synonym: "decreased pheromone-induced mitotic cell cycle arrest" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mitotic cell cycle arrest in response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0000530 ! abnormal mitotic cell cycle arrest in response to pheromone created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000533 name: normal mitotic cell cycle arrest in response to pheromone def: "A cellular process phenotype in which mitotic cell cycle arrest in response to pheromone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal pheromone-induced mitotic cell cycle arrest" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression is_a: FYPO:0000532 ! decreased mitotic cell cycle arrest in response to pheromone is_a: FYPO:0001025 ! normally arrested mitotic cell cycle progression created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000534 name: abnormal mitotic spindle pole body localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is abnormal. Spindle pole body localization is the process in which a whole spindle pole body is transported to, or maintained in, a specific location." [GO:0070631, PomBase:mah] synonym: "abnormal mitotic SPB localization" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body localisation" EXACT [PomBase:mah] synonym: "abnormal position of mitotic spindle pole body" RELATED [PomBase:mah] synonym: "abnormal spindle pole body localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle pole body localization during vegetative growth" EXACT [PomBase:mah] synonym: "position of spindle pole body: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000535 name: normal mitotic spindle pole body localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is normal (i.e. indistinguishable from wild type). Spindle pole body localization is the process in which a whole spindle pole body is transported to, or maintained in, a specific location." [GO:0070631, PomBase:mah] synonym: "normal mitotic SPB localization" EXACT [PomBase:mah] synonym: "normal mitotic spindle pole body localisation" EXACT [PomBase:mah] synonym: "normal position of mitotic spindle pole body" RELATED [PomBase:mah] synonym: "normal spindle pole body localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spindle pole body localization during vegetative growth" EXACT [PomBase:mah] synonym: "position of spindle pole body: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000536 name: abnormal protein secretion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein secretion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein secretion: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000540 ! abnormal protein transport during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000537 name: abolished protein secretion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein secretion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent protein secretion during vegetative growth" EXACT [PomBase:mah] synonym: "protein secretion abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein secretion: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000536 ! abnormal protein secretion during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000538 name: decreased protein secretion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein secretion is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein secretion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein secretion: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced protein secretion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000536 ! abnormal protein secretion during vegetative growth is_a: FYPO:0000541 ! decreased protein transport during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000539 name: increased protein secretion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein secretion is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein secretion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein secretion: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000536 ! abnormal protein secretion during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000540 name: abnormal protein transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein transport: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0005744 ! abnormal protein transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000541 name: decreased protein transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein transport is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein transport: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced protein transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000540 ! abnormal protein transport during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000542 name: increased rate of protein transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein transport is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased rate of protein transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein transport: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000540 ! abnormal protein transport during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000544 name: abolished protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification does not occur. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein/peptide modification during vegetative growth" EXACT [PomBase:mah] synonym: "absent protein/peptide modification during vegetative growth" EXACT [PomBase:mah] synonym: "protein modification abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0002497 ! abolished protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000545 name: decreased protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein modification is decreased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein/peptide modification during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0002498 ! decreased protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000546 name: delayed onset of protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification begins later than normal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein/peptide modification during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "protein/peptide modification: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000547 name: increased protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein modification is increased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein/peptide modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0002499 ! increased protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000548 name: increased duration of protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein modification processes is longer than normal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein/peptide modification during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "protein/peptide modification: increased duration" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000549 name: normal protein modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process during vegetative growth is_a: FYPO:0002495 ! normal protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000550 name: abnormal pseudohyphal growth alt_id: FYPO:0000435 def: "A cellular process phenotype in which pseudohyphal growth is abnormal." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abnormal filamentous growth" BROAD [PomBase:mah] synonym: "filamentous growth: abnormal" BROAD [SGD:phenotype_annotation] synonym: "pseudohyphal growth: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000551 name: pseudohyphal growth abolished alt_id: FYPO:0000436 def: "A cellular process phenotype in which pseudohyphal growth does not occur." [PomBase:mah] synonym: "abolished filamentous growth" BROAD [PomBase:mah] synonym: "abolished pseudohyphal growth" EXACT [PomBase:mah] synonym: "absent filamentous growth" BROAD [PomBase:mah] synonym: "absent pseudohyphal growth" EXACT [PomBase:mah] synonym: "filamentous growth abolished" BROAD [PomBase:mah] synonym: "filamentous growth: absent" BROAD [SGD:phenotype_annotation] synonym: "pseudohyphal growth: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000550 ! abnormal pseudohyphal growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000552 name: decreased pseudohyphal growth alt_id: FYPO:0000437 def: "A cellular process phenotype in which the occurrence of pseudohyphal growth is decreased." [PomBase:mah] synonym: "decreased filamentous growth" BROAD [PomBase:mah] synonym: "filamentous growth: decreased" BROAD [SGD:phenotype_annotation] synonym: "pseudohyphal growth: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced pseudohyphal growth" EXACT [PomBase:mah] is_a: FYPO:0000550 ! abnormal pseudohyphal growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000553 name: increased pseudohyphal growth during cellular hyperosmotic response alt_id: FYPO:0000438 def: "A cellular process phenotype in which the occurrence of pseudohyphal growth is increased during a cellular hyperosmotic response." [PomBase:mah] synonym: "increased filamentous growth during cellular hyperosmotic response" BROAD [PomBase:mah] is_a: FYPO:0003776 ! increased pseudohyphal growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000554 name: normal pseudohyphal growth alt_id: FYPO:0000439 def: "A cell population phenotype in which pseudohyphal growth is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "filamentous growth: normal" BROAD [SGD:phenotype_annotation] synonym: "normal filamentous growth" BROAD [PomBase:mah] synonym: "pseudohyphal growth: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000555 name: abnormal re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest is abnormal." [PomBase:mah] synonym: "abnormal recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000302 ! abnormal response to pheromone created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000556 name: abolished re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest does not occur." [PomBase:mah] synonym: "absent recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "re-entry into mitotic cell cycle after pheromone arrest abolished" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest abolished" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000557 name: decreased re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle after pheromone arrest is decreased." [PomBase:mah] synonym: "decreased recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced re-entry into mitotic cell cycle after pheromone arrest" EXACT [PomBase:mah] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000558 name: increased re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle after pheromone arrest is increased." [PomBase:mah] synonym: "increased recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000559 name: increased rate of re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which the rate, or speed, of re-entry into the mitotic cell cycle after pheromone arrest is increased." [PomBase:mah] synonym: "increased rate of recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000560 name: normal re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000561 name: normal mitotic G1 phase progression def: "A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: normal" RELATED [SGD:phenotype_annotation] synonym: "normal G1 phase progression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle progression in G1" EXACT [PomBase:mah] synonym: "normal mitotic G1 phase progression during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000562 name: abolished cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration does not occur." [PomBase:mah] synonym: "abolished cellular respiration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent respiratory metabolism" EXACT [PomBase:mah] synonym: "cellular respiration abolished" EXACT [PomBase:mah] synonym: "cellular respiration abolished during vegetative growth" EXACT [PomBase:mah] synonym: "respiration abolished" BROAD [PomBase:mah] synonym: "respiratory metabolism abolished" EXACT [PomBase:mah] synonym: "respiratory metabolism: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000563 name: abnormal mitotic G2 phase progression def: "A cellular process phenotype in which progression through the G2 phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal G2 phase progression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in G2" EXACT [PomBase:mah] synonym: "abnormal mitotic G2 phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G2 phase: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002736 ! abnormal mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000564 name: decreased rate of cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of cellular respiration is decreased." [PomBase:mah] synonym: "decreased rate of cellular respiration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of respiration" BROAD [PomBase:mah] synonym: "decreased rate of respiratory metabolism" EXACT [PomBase:mah] synonym: "reduced rate of cellular respiration" EXACT [PomBase:mah] synonym: "respiratory metabolism: decreased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000565 name: increased cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular respiration is increased." [PomBase:mah] synonym: "increased cellular respiration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "increased respiration" BROAD [PomBase:mah] synonym: "increased respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000566 name: normal cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular respiration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "normal respiration" BROAD [PomBase:mah] synonym: "normal respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000567 name: decreased duration of septum assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septum assembly is shorter than normal." [PomBase:mah] synonym: "decreased division septum formation involved in mitotic cytokinesis" RELATED [PomBase:mah] synonym: "decreased duration of division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "decreased duration of division septum formation involved in mitotic cytokinesis" EXACT [PomBase:mah] synonym: "decreased duration of septation" BROAD [GO:0000917, PomBase:mah] synonym: "decreased duration of septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased septation" RELATED [PomBase:mah] synonym: "decreased septum formation" RELATED [PomBase:mah] synonym: "reduced duration of septum assembly" EXACT [PomBase:mah] synonym: "septum formation: decreased" BROAD [SGD:phenotype_annotation] is_a: FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000568 name: abnormal shmoo formation def: "A cellular process phenotype in which mating projection assembly is abnormal." [PomBase:mah] synonym: "abnormal conjugation tube formation" EXACT [PomBase:mah] synonym: "abnormal mating projection assembly" EXACT [PomBase:mah] synonym: "abnormal mating projection formation" EXACT [PomBase:mah] synonym: "abnormal shmoo assembly" EXACT [PomBase:mah] synonym: "shmoo formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000569 name: abolished shmoo formation def: "A cellular process phenotype in which mating projection assembly does not occur." [PomBase:mah] synonym: "abolished conjugation tube formation" EXACT [PomBase:mah] synonym: "absent shmoo formation" EXACT [PomBase:mah] synonym: "mating projection assembly abolished" EXACT [PomBase:mah] synonym: "mating projection formation abolished" EXACT [PomBase:mah] synonym: "shmoo assembly abolished" EXACT [PomBase:mah] synonym: "shmoo formation abolished" EXACT [PomBase:mah] synonym: "shmoo formation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000570 name: decreased shmoo formation def: "A cellular process phenotype in which the occurrence of mating projection assembly is decreased." [PomBase:mah] synonym: "decreased conjugation tube formation" EXACT [PomBase:mah] synonym: "decreased mating projection assembly" EXACT [PomBase:mah] synonym: "decreased mating projection formation" EXACT [PomBase:mah] synonym: "decreased shmoo assembly" EXACT [PomBase:mah] synonym: "reduced shmoo formation" EXACT [PomBase:mah] synonym: "shmoo formation: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000571 name: decreased rate of shmoo formation def: "A cellular process phenotype in which the rate, or speed, of mating projection assembly is decreased." [PomBase:mah] synonym: "decreased rate of conjugation tube formation" EXACT [PomBase:mah] synonym: "decreased rate of mating projection assembly" EXACT [PomBase:mah] synonym: "decreased rate of mating projection formation" EXACT [PomBase:mah] synonym: "decreased rate of shmoo assembly" EXACT [PomBase:mah] synonym: "reduced rate of shmoo formation" EXACT [PomBase:mah] synonym: "shmoo formation: decreased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000572 name: increased rate of shmoo formation def: "A cellular process phenotype in which the rate, or speed, of mating projection assembly is increased." [PomBase:mah] synonym: "increased rate of conjugation tube formation" EXACT [PomBase:mah] synonym: "increased rate of mating projection assembly" EXACT [PomBase:mah] synonym: "increased rate of mating projection formation" EXACT [PomBase:mah] synonym: "increased rate of shmoo assembly" EXACT [PomBase:mah] synonym: "shmoo formation: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000573 name: normal shmoo formation def: "A cellular process phenotype in which mating projection assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal conjugation tube formation" EXACT [PomBase:mah] synonym: "normal mating projection assembly" EXACT [PomBase:mah] synonym: "normal mating projection formation" EXACT [PomBase:mah] synonym: "normal shmoo assembly" EXACT [PomBase:mah] synonym: "shmoo formation: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000574 name: abnormal gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing is abnormal." [PomBase:mah] synonym: "abnormal gene silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000575 name: abolished gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing does not occur." [PomBase:mah] synonym: "abolished gene silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent silencing" EXACT [PomBase:mah] synonym: "gene silencing abolished" EXACT [PomBase:mah] synonym: "gene silencing abolished during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000574 ! abnormal gene silencing created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000576 name: decreased gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of gene silencing is decreased." [PomBase:mah] synonym: "decreased gene silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "reduced gene silencing" EXACT [PomBase:mah] synonym: "silencing: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000574 ! abnormal gene silencing created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000577 name: increased gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of gene silencing is increased." [PomBase:mah] synonym: "increased gene silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000574 ! abnormal gene silencing relationship: has_output FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000578 name: normal gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal gene silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000579 name: normal spore germination def: "A cellular process phenotype in which spore germination is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal spore germination frequency" RELATED [PomBase:mah] synonym: "normal spore viability" RELATED [PomBase:mah] synonym: "spore germination: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000580 name: abnormal ascospore wall biogenesis def: "A cellular process phenotype in which ascospore wall biogenesis is abnormal." [PomBase:mah] synonym: "abnormal ascospore wall organization" RELATED [PomBase:mah] synonym: "abnormal spore wall formation" RELATED [PomBase:mah] synonym: "abnormal spore wall organization" RELATED [PomBase:vw] synonym: "spore wall formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000174 ! abnormal cell wall biogenesis is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000581 name: decreased spore germination frequency def: "A cell population phenotype in which the frequency of occurrence of spore germination is decreased." [PomBase:mah] comment: Note that this phenotype is usually assayed by observing a population of spores and observing how many germinate. Also consider annotating to 'inviable spore (FYPO:0002151)' with an extension to indicate incomplete penetrance, especially if you have a quantitative measurement. synonym: "decreased spore germination" EXACT [PomBase:mah] synonym: "decreased spore viability" RELATED [PomBase:mah] synonym: "reduced spore germination frequency" EXACT [PomBase:mah] synonym: "reduced spore viability" RELATED [PomBase:mah] synonym: "spore germination: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000582 name: decreased rate of spore germination def: "A cellular process phenotype in which the rate, or speed, of spore germination is decreased." [PomBase:mah] synonym: "reduced rate of spore germination" EXACT [PomBase:mah] synonym: "spore germination: decreased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000305 ! abnormal spore germination created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000583 name: abolished sporulation def: "A cellular process phenotype in which ascospore formation does not occur." [PomBase:mah] synonym: "absent sporulation" EXACT [PomBase:mah] synonym: "ascospore formation abolished" EXACT [PomBase:mah] synonym: "sporulation abolished" EXACT [PomBase:mah] synonym: "sporulation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000584 name: decreased sporulation frequency def: "A cell population phenotype in which the frequency of occurrence of ascospore formation is decreased." [PomBase:mah] synonym: "decreased frequency of ascospore formation" EXACT [PomBase:mah] synonym: "decreased spore viability" RELATED [PomBase:vw] synonym: "decreased sporulation" EXACT [PomBase:mah] synonym: "reduced spore viability" RELATED [PomBase:vw] synonym: "reduced sporulation frequency" EXACT [PomBase:mah] synonym: "sporulation: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000585 name: abolished ascospore wall biogenesis def: "A cellular process phenotype in which ascospore wall biogenesis does not occur." [PomBase:mah] synonym: "absent spore wall formation" RELATED [PomBase:mah] synonym: "ascospore wall biogenesis abolished" EXACT [PomBase:mah] synonym: "spore wall formation abolished" RELATED [PomBase:mah] synonym: "spore wall formation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000580 ! abnormal ascospore wall biogenesis created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000586 name: abolished ascospore wall assembly def: "A cellular process phenotype in which ascospore wall assembly does not occur." [PomBase:mah] synonym: "absent spore wall formation" RELATED [PomBase:mah] synonym: "ascospore wall assembly abolished" EXACT [PomBase:mah] synonym: "spore wall formation abolished" RELATED [PomBase:mah] synonym: "spore wall formation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000175 ! abnormal ascospore wall assembly created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000587 name: delayed onset of sporulation def: "A cellular process phenotype in which ascospore formation begins later than normal." [PomBase:mah] synonym: "delayed onset of ascospore formation" EXACT [PomBase:mah] synonym: "delayed sporulation" EXACT [PomBase:mah] synonym: "sporulation: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000588 name: increased sporulation frequency def: "A cell population phenotype in which the frequency of occurrence of ascospore formation is increased." [PomBase:mah] synonym: "increased frequency of ascospore formation" EXACT [PomBase:mah] synonym: "increased sporulation" EXACT [PomBase:mah] synonym: "sporulation: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000589 name: increased rate of sporulation def: "A cellular process phenotype in which the rate, or speed, of ascospore formation is increased, i.e. sporulation takes place more rapidly than in wild type." [PomBase:mah] synonym: "increased rate of ascospore formation" EXACT [PomBase:mah] synonym: "sporulation: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000590 name: normal sporulation def: "A cellular process phenotype in which ascospore formation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal ascospore formation" EXACT [PomBase:mah] synonym: "sporulation: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000591 name: abnormal transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition is abnormal." [PomBase:mah] synonym: "abnormal transposable element transposition" EXACT [PomBase:mah] synonym: "abnormal transposition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000592 name: abolished transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition does not occur." [PomBase:mah] synonym: "abolished transposition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent transposable element transposition" EXACT [PomBase:mah] synonym: "transposable element transposition abolished" EXACT [PomBase:mah] synonym: "transposable element transposition: absent" RELATED [SGD:phenotype_annotation] synonym: "transposition abolished" EXACT [PomBase:mah] synonym: "transposition abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000593 name: decreased transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is decreased." [PomBase:mah] synonym: "decreased transposable element transposition" EXACT [PomBase:mah] synonym: "decreased transposition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transposition during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transposition" EXACT [PomBase:mah] synonym: "transposable element transposition: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000594 name: increased transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is increased." [PomBase:mah] synonym: "increased transposable element transposition" EXACT [PomBase:mah] synonym: "increased transposition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000595 name: increased rate of transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of transposition is increased." [PomBase:mah] synonym: "increased rate of transposable element transposition" EXACT [PomBase:mah] synonym: "increased rate of transposition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000596 name: normal transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal transposable element transposition" EXACT [PomBase:mah] synonym: "normal transposition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000597 name: abnormal vacuolar transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is abnormal." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "abnormal vacuolar protein transport during vegetative growth" NARROW [PomBase:mah] synonym: "abnormal vacuolar transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal vacuole transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0003578 ! abnormal vacuolar transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000598 name: decreased vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of vacuolar transport is decreased." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "decreased vacuolar protein transport" NARROW [PomBase:mah] synonym: "decreased vacuolar transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "reduced vacuolar transport" EXACT [PomBase:mah] synonym: "vacuolar transport: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000599 name: decreased rate of vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of vacuolar transport is decreased." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "decreased rate of vacuolar protein transport" NARROW [PomBase:mah] synonym: "decreased rate of vacuolar transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of vacuolar transport" EXACT [PomBase:mah] synonym: "vacuolar transport: decreased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000600 name: delayed onset of vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport begins later than normal." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "delayed onset of vacuolar protein transport" NARROW [PomBase:mah] synonym: "delayed onset of vacuolar transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "delayed vacuolar transport" EXACT [PomBase:mah] synonym: "vacuolar transport: delayed" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000601 name: normal vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "normal vacuolar protein transport" NARROW [PomBase:mah] synonym: "normal vacuolar transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "vacuolar transport: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000602 name: abnormal mitotic G1 phase progression def: "A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal G1 phase progression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in G1" EXACT [PomBase:mah] synonym: "abnormal mitotic G1 phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002736 ! abnormal mitotic cell cycle phase created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000603 name: decreased duration of mitotic G1 phase def: "A cellular process phenotype in which the duration of G1 phase of a mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "decreased duration of G1 phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased duration of mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: decreased duration" RELATED [SGD:phenotype_annotation] synonym: "reduced duration of mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000602 ! abnormal mitotic G1 phase progression is_a: FYPO:0001070 ! decreased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000607 name: abnormal mitotic M phase progression def: "A cellular process phenotype in which progression through M phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal M phase progression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in M" EXACT [PomBase:mah] synonym: "abnormal mitotic M phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in M phase: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002736 ! abnormal mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000608 name: abnormal cell cycle arrest in mitotic M phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase under conditions where arrest does not normally occur." [PomBase:mah] comment: M phase is often identified by the degree of chromosome condensation. Use this term for terminal arrest. If arrest is transient, consider using 'increased duration of mitotic cell cycle phase' (FYPO:0001069) or one of its more specific descendants. synonym: "abnormal cell cycle arrest in M phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic M phase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in M phase" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with condensed chromosomes" RELATED [PomBase:vw] synonym: "abnormal mitotic nuclear division arrest" EXACT [PomBase:vw] synonym: "mitotic cell cycle arrest in M-phase" EXACT [PomBase:vw] synonym: "mitotic cell cycle progression in M phase: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression is_a: FYPO:0000607 ! abnormal mitotic M phase progression is_a: FYPO:0001334 ! regulation phenotype during vegetative growth relationship: has_output FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000610 name: abnormal mitotic S phase progression def: "A cellular process phenotype in which progression through S phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in S" EXACT [PomBase:mah] synonym: "abnormal mitotic S phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal S phase progression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in S phase: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002736 ! abnormal mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000611 name: abnormal cell cycle arrest in mitotic S phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested in S phase." [PomBase:mah] comment: Cells arrested in S phase typically have more than 1C, but less than 2C, DNA content. Use this term for terminal arrest. If arrest is transient, consider using 'increased duration of mitotic cell cycle phase' (FYPO:0001069) or one of its more specific descendants. synonym: "abnormal cell cycle arrest in mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in S phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in S phase" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with incompletely replicated DNA" EXACT [PomBase:al] synonym: "mitotic cell cycle progression in S phase: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000614 name: increased duration of mitotic S phase alt_id: FYPO:0000612 alt_id: FYPO:0000613 def: "A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is longer than normal." [PomBase:mah] synonym: "decreased rate of mitotic S phase progression" RELATED [PomBase:mah] synonym: "delayed mitotic S phase progression" RELATED [PomBase:mah] synonym: "delayed mitotic S phase progression during vegetative growth" RELATED [PomBase:mah] synonym: "increased duration of mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of S phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased S phase index" RELATED [PomBase:al] synonym: "mitotic cell cycle progression in S phase: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in S phase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in S phase: increased duration" RELATED [SGD:phenotype_annotation] synonym: "prolonged mitotic S phase" EXACT [PomBase:mah] synonym: "reduced rate of mitotic S phase progression" RELATED [PomBase:mah] is_a: FYPO:0000610 ! abnormal mitotic S phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000615 name: decreased duration of mitotic S phase def: "A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "decreased duration of mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of S phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in S phase: increased rate" RELATED [SGD:phenotype_annotation] synonym: "reduced duration of mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0000610 ! abnormal mitotic S phase progression is_a: FYPO:0001070 ! decreased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000616 name: abnormal mitotic anaphase progression def: "A cellular process phenotype in which progression through mitotic anaphase is abnormal." [PomBase:mah] synonym: "abnormal anaphase progression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic anaphase progression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in anaphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in anaphase: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000607 ! abnormal mitotic M phase progression created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000618 name: increased duration of mitotic anaphase alt_id: FYPO:0000617 def: "A cellular process phenotype in which the duration of progression through anaphase of mitosis is longer than normal." [PomBase:mah] synonym: "delayed mitotic anaphase progression" RELATED [PomBase:mah] synonym: "increased duration of anaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase progression" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in anaphase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in anaphase: increased duration" RELATED [SGD:phenotype_annotation] synonym: "prolonged mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0000616 ! abnormal mitotic anaphase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000619 name: abnormal cell cycle arrest in mitotic anaphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in anaphase under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormal cell cycle arrest in anaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic anaphase with condensed chromosomes" EXACT [PomBase:vw] synonym: "abnormal mitotic cell cycle arrest in anaphase" EXACT [GO:0000090] synonym: "mitotic cell cycle progression in late anaphase: arrested" NARROW [SGD:phenotype_annotation] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000620 name: abnormal cell cycle arrest in mitotic metaphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase under conditions where arrest does not normally occur." [PomBase:mah] comment: Metaphase is defined as the part of mitosis when chromosomes are aligned in the middle of the spindle. If no spindle is present, do not use this term, but consider 'abnormal cell cycle arrest in mitotic prophase' (FYPO:0003145). Also do not use this term if the spindle has elongated at all. If the spindle has elongated, or you cannot tell whether a spindle is present, or metaphase cannot be clearly detected, annotate to the more general term 'abnormal cell cycle arrest in mitotic M phase' (FYPO:0000608). In cells that arrest in metaphase, chromosome separation does not occur. synonym: "abnormal cell cycle arrest in metaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest with unseparated chromosomes" RELATED [PomBase:vw] synonym: "abnormal mitotic cell cycle arrest in metaphase" EXACT [GO:0000089] synonym: "abolished mitotic metaphase/anaphase transition" RELATED [PomBase:mah] synonym: "mitotic cell cycle progression in metaphase: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase relationship: has_output FYPO:0001946 ! abolished mitotic sister chromatid separation created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000621 name: delayed onset of mitotic metaphase def: "A cellular process phenotype in which the onset of metaphase of mitosis begins later than normal." [PomBase:mah] synonym: "delayed mitotic metaphase" EXACT [PomBase:mah] synonym: "delayed onset of metaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "delayed onset of mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in metaphase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic metaphase delay" EXACT [PomBase:mah] is_a: FYPO:0000607 ! abnormal mitotic M phase progression created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000622 name: abnormal cell cycle arrest in mitotic telophase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in telophase under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in telophase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in telophase" EXACT [GO:0000093] synonym: "mitotic cell cycle progression in telophase: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000623 name: abnormal positive regulation of transcription def: "A transcription regulation phenotype in which any process of positive regulation of transcription is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. There may be enough evidence to support annotation to a more specific term such as 'abnormal transcriptional response to pheromone' (FYPO:0000984); if not, it is safer to annotate to 'increased transcription during vegetative growth' (FYPO:0000780) or 'decreased transcription during vegetative growth' (FYPO:0000781) rather than explicitly claiming that an effect on regulation was observed. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal activation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal activation of transcription, DNA-dependent" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of cellular transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal stimulation of gene-specific transcription" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal stimulation of transcription, DNA-dependent" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal up regulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal up regulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal up-regulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal up-regulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal upregulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal upregulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype created_by: midori creation_date: 2011-08-19T03:38:05Z [Term] id: FYPO:0000624 name: abnormal negative regulation of transcription during vegetative growth def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which any process of negative regulation of transcription is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. There may be enough evidence to support annotation to a more specific term such as 'abnormal chromatin silencing' (FYPO:0000144); if not, it is safer to annotate to 'increased transcription during vegetative growth' (FYPO:0000780) or 'decreased transcription during vegetative growth' (FYPO:0000781) rather than explicitly claiming that an effect on regulation was observed. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal down regulation of gene-specific transcription during vegetative growth" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal down regulation of transcription, DNA-dependent, during vegetative growth" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal down-regulation of gene-specific transcription during vegetative growth" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal down-regulation of transcription, DNA-dependent, during vegetative growth" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal downregulation of gene-specific transcription during vegetative growth" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal downregulation of transcription, DNA-dependent, during vegetative growth" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal inhibition of gene-specific transcription during vegetative growth" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal inhibition of transcription, DNA-dependent, during vegetative growth" NARROW [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of cellular transcription, DNA-dependent, during vegetative growth" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of gene-specific transcription during vegetative growth" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of transcription, DNA-dependent, during vegetative growth" EXACT [GO:0045892, PomBase:mah] is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth created_by: midori creation_date: 2011-08-19T03:40:47Z [Term] id: FYPO:0000625 name: abnormal premeiotic DNA replication def: "A cellular process phenotype in which premeiotic DNA replication is abnormal." [PomBase:mah] synonym: "abnormal meiotic DNA replication" RELATED [GO:0006279, GOC:mah] synonym: "abnormal meiotic DNA synthesis" RELATED [GO:0006279, GOC:mah] synonym: "abnormal premeiotic DNA synthesis" RELATED [GO:0006279, GOC:mah] is_a: FYPO:0000217 ! abnormal DNA replication created_by: midori creation_date: 2011-08-19T03:48:13Z [Term] id: FYPO:0000626 name: abnormal initiation of premeiotic DNA replication def: "A cellular process phenotype in which the initiation of premeiotic DNA replication is abnormal." [PomBase:mah] synonym: "abnormal initiation of meiotic DNA synthesis" RELATED [GO:0072691, GOC:mah] synonym: "abnormal initiation of premeiotic DNA synthesis" RELATED [GO:0072691, GOC:mah] synonym: "abnormal meiotic DNA replication initiation" RELATED [GO:0072691, GOC:mah] synonym: "abnormal premeiotic DNA replication initiation" EXACT [GO:0072691, GOC:mah] is_a: FYPO:0000176 ! abnormal DNA replication initiation is_a: FYPO:0000625 ! abnormal premeiotic DNA replication created_by: midori creation_date: 2011-08-19T03:49:02Z [Term] id: FYPO:0000627 name: normal cellular process def: "A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2011-08-19T04:05:16Z [Term] id: FYPO:0000628 name: abnormal cellular process def: "A phenotype in which a specific cellular process is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2011-08-19T04:06:34Z [Term] id: FYPO:0000629 name: abnormal apoptotic process def: "A cellular process phenotype in which programmed cell death by apoptosis is abnormal. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "abnormal apoptosis" NARROW [GO:0006915] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-19T04:10:09Z [Term] id: FYPO:0000630 name: abnormal biofilm formation def: "A cellular process phenotype in which biofilm formation is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-19T04:12:58Z [Term] id: FYPO:0000631 name: cell cycle phenotype def: "A cellular process phenotype that affects progression of the mitotic or meiotic cell cycle, or regulation of cell cycle progression." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cell-division cycle phenotype" EXACT [GO:0007049, PomBase:mah] synonym: "fission yeast cell cycle phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-08-19T04:16:04Z [Term] id: FYPO:0000632 name: mitochondrial translation phenotype def: "A cellular process phenotype that affects mitochondrial translation." [PomBase:mah] synonym: "fission yeast mitochondrial translation phenotype" EXACT [PomBase:mah] synonym: "mitochondrial translation phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial translation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000291 ! translation phenotype created_by: midori creation_date: 2011-08-23T04:58:17Z [Term] id: FYPO:0000633 name: sensitive to G418 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to G418. Cells stop growing (and may die) at a concentration of G418 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to G418" EXACT [PomBase:mah] synonym: "sensitive to G418 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to G418 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to Geneticin" EXACT [CHEBI:42768, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-08-23T04:58:25Z [Term] id: FYPO:0000634 name: abolished protein localization to centromere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localisation to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "abolished protein localization to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromosome, centric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "abolished protein localization to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "protein absent from centromere during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to centromere abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2011-08-23T04:58:31Z [Term] id: FYPO:0000635 name: growth auxotrophic for leucine def: "Auxotrophy in which a cell is unable to synthesize leucine, and therefore requires leucine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for leucine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for leucine during vegetative growth" EXACT [PomBase:mah] synonym: "leucine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-08-23T05:17:07Z [Term] id: FYPO:0000636 name: increased cell population growth rate def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced cell population growth" RELATED [PomBase:mah] synonym: "fast cell population growth" EXACT [PomBase:mah] synonym: "increased cell population growth rate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell population growth rate during vegetative growth" EXACT [PomBase:mah] synonym: "increased cell population proliferation" RELATED [PomBase:vw] synonym: "increased cell proliferation" RELATED [PomBase:vw] is_a: FYPO:0001356 ! abnormal vegetative cell population growth is_a: FYPO:0003937 ! increased cell population growth created_by: midori creation_date: 2011-08-31T01:30:12Z [Term] id: FYPO:0000637 name: increased cell population growth rate on glucose carbon source def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing glucose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced growth on glucose" RELATED [PomBase:mah] synonym: "fast cell population growth on glucose carbon source" EXACT [PomBase:mah] synonym: "increased cell population proliferation on glucose carbon source" RELATED [PomBase:vw] synonym: "increased cell proliferation on glucose carbon source" RELATED [PomBase:vw] synonym: "increased vegetative cell population growth rate on glucose carbon source" EXACT [PomBase:mah] is_a: FYPO:0000636 ! increased cell population growth rate is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2011-08-31T02:20:29Z [Term] id: FYPO:0000639 name: delayed onset of septum assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly begins later than normal." [PomBase:al, PomBase:mah] synonym: "delayed onset of division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "delayed onset of division septum formation involved in mitotic cytokinesis" EXACT [PomBase:mah] synonym: "delayed onset of septation" BROAD [GO:0000917, PomBase:mah] synonym: "delayed onset of septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of septum formation" EXACT [PomBase:mah] synonym: "delayed septum assembly" EXACT [PomBase:mah] is_a: FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2011-08-31T02:55:54Z [Term] id: FYPO:0000640 name: abnormal chromatin silencing at centromere central core def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal at the centromere central core. Chromatin silencing is the observed effect of processes that repress transcription at the centromere central core, which is normally assembled into CENP-A-containing chromatin." [PomBase:mah, PomBase:vw] comment: Note that the centromere central core corresponds to SO:0001796. Chromatin silencing phenotypes at the centromere central core may reflect the assembly or maintenance of CENP-A-containing chromatin. See the GO cellular component term 'CENP-A containing chromatin' (GO:0061638), and the biological process term 'CENP-A containing chromatin organization' (GO:0061641). synonym: "abnormal centromere central core chromatin silencing" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromeric central core" EXACT [PomBase:mah] synonym: "abnormal negative regulation of transcription at centromere central core" RELATED [PomBase:mah] synonym: "abnormal transcriptional repression at centromere central core" RELATED [PomBase:mah] is_a: FYPO:0004527 ! abnormal regulation of transcription during vegetative growth created_by: midori creation_date: 2011-09-12T03:33:40Z [Term] id: FYPO:0000641 name: abnormal chromosome organization def: "A cellular process phenotype in which any process of chromosome organization is abnormal. Chromosome organization results in the assembly, arrangement of constituent parts, or disassembly of chromosomes." [GO:0051276, PomBase:mah] synonym: "abnormal chromosome organisation" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2011-09-28T12:10:13Z [Term] id: FYPO:0000642 name: abnormal chromatin organization def: "A cellular process phenotype in which any process of chromatin organization is abnormal. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] synonym: "abnormal chromatin organisation" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2011-09-28T12:16:57Z [Term] id: FYPO:0000643 name: abnormal mitotic DNA integrity checkpoint def: "A cell cycle checkpoint phenotype in which a mitotic DNA integrity checkpoint is abnormal. A DNA integrity checkpoint normally regulates cell cycle progression in response to changes in DNA structure. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal mitotic DNA integrity checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0001704 ! abnormal mitotic cell cycle checkpoint created_by: midori creation_date: 2011-09-28T12:28:26Z [Term] id: FYPO:0000644 name: normal protein localization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular protein localization is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localisation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2011-10-05T04:52:48Z [Term] id: FYPO:0000645 name: small vegetative cell def: "A cell morphology phenotype in which a vegetative cell has an abnormally low volume." [PomBase:mah] synonym: "decreased vegetative cell size" EXACT [PomBase:mah] synonym: "reduced vegetative cell size" EXACT [PomBase:mah] is_a: FYPO:0000023 ! small cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2011-10-07T02:03:07Z [Term] id: FYPO:0000646 name: swollen vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "enlarged vegetative cell" RELATED [PomBase:mah] synonym: "increased vegetative cell size" RELATED [PomBase:vw] synonym: "increased vegetative cell volume" EXACT [PomBase:mah] synonym: "large vegetative cell" RELATED [PomBase:vw] is_a: FYPO:0000025 ! swollen cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2011-10-07T04:19:54Z [Term] id: FYPO:0000647 name: vegetative cell lysis def: "An inviable phenotype in which a vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] synonym: "cell lysis during vegetative growth" EXACT [PomBase:mah] synonym: "cytolysis during vegetative growth" EXACT [PomBase:mah] synonym: "inviable, lysed vegetative cell" EXACT [PomBase:mah] synonym: "vegetative cell lysis during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell is_a: FYPO:0002488 ! cell lysis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2011-10-10T03:28:02Z [Term] id: FYPO:0000648 name: viable small vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable but has an abnormally low volume. Note that small viable cells may result from a cell cycle size regulation defect." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "mitosis with small cell size" RELATED [PomBase:vw] synonym: "reduced size at cell division" RELATED [PomBase:vw] synonym: "small viable vegetative cell" EXACT [PomBase:mah] synonym: "viable small cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable small vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000645 ! small vegetative cell is_a: FYPO:0001491 ! viable vegetative cell relationship: has_part FYPO:0000645 ! small vegetative cell relationship: has_part FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2011-10-13T12:06:45Z [Term] id: FYPO:0000650 name: increased septation index def: "A cell population phenotype in which the septation index is higher than normal. The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for wild type." [PomBase:mah, PomBase:vw] synonym: "increased number of septated cells" EXACT [PomBase:vw] synonym: "increased septation" RELATED [PomBase:mah] synonym: "septated" RELATED [PomBase:vw] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-10-13T12:34:42Z [Term] id: FYPO:0000651 name: increased duration of septum assembly alt_id: FYPO:0000649 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septum assembly is longer than normal." [PomBase:mah] synonym: "increased division septum formation involved in mitotic cytokinesis" RELATED [PomBase:mah] synonym: "increased duration of division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "increased duration of division septum formation involved in mitotic cytokinesis" EXACT [PomBase:mah] synonym: "increased duration of septation" BROAD [GO:0000917, PomBase:mah] synonym: "increased duration of septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of septum formation" BROAD [PomBase:mah] synonym: "increased septation" RELATED [PomBase:mah] synonym: "increased septum formation" RELATED [PomBase:mah] synonym: "prolonged septum assembly" EXACT [PomBase:mah] is_a: FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2011-10-13T03:07:53Z [Term] id: FYPO:0000652 name: molecular function phenotype def: "A phenotype that affects a molecular function such as binding or catalytic activity." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast molecular function phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-11-11T10:42:36Z [Term] id: FYPO:0000653 name: DNA binding phenotype def: "A phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast DNA binding phenotype" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2011-11-11T10:43:39Z [Term] id: FYPO:0000654 name: catalytic activity phenotype def: "A phenotype that affects a catalytic activity." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "enzymatic activity phenotype" EXACT [PomBase:mah] synonym: "fission yeast catalytic activity phenotype" EXACT [PomBase:mah] is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2011-11-11T10:44:09Z [Term] id: FYPO:0000655 name: normal DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] is_a: FYPO:0000653 ! DNA binding phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000656 name: abnormal DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds DNA differently from wild type, or that a mutation in one gene affects DNA binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000653 ! DNA binding phenotype is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000657 name: increased DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000658 name: decreased DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000659 name: abolished DNA binding def: "A molecular function phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "DNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000660 name: normal catalytic activity def: "A molecular function phenotype in which the observed rate and other catalytic properties of a specified catalytic activity are normal (i.e. indistinguishable from wild type)." [PomBase:mah] subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000654 ! catalytic activity phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000661 name: abnormal catalytic activity def: "A molecular function phenotype in which the observed rate or other catalytic property of a specified catalytic activity is abnormal." [PomBase:mah] is_a: FYPO:0000654 ! catalytic activity phenotype is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000662 name: increased catalytic activity def: "A molecular function phenotype in which the observed rate of a specified catalytic activity is increased." [PomBase:mah] subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000663 name: decreased catalytic activity def: "A molecular function phenotype in which the observed rate of a specified catalytic activity is decreased." [PomBase:mah] subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "reduced catalytic activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000664 name: abolished catalytic activity def: "A molecular function phenotype in which a specified catalytic activity is absent." [PomBase:mah] subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "catalytic activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000665 name: normal peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal protease activity" EXACT [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000666 name: abnormal peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is abnormal." [PomBase:mah] synonym: "abnormal protease activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000667 name: increased peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is increased." [PomBase:mah] synonym: "increased protease activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000666 ! abnormal peptidase activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000668 name: decreased peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is decreased." [PomBase:mah] synonym: "decreased protease activity" EXACT [PomBase:mah] synonym: "reduced peptidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000666 ! abnormal peptidase activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000669 name: abolished peptidase activity def: "A molecular function phenotype in which a peptidase activity is absent." [PomBase:mah] synonym: "abolished protease activity" EXACT [PomBase:mah] synonym: "peptidase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000666 ! abnormal peptidase activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000670 name: abnormal mitotic sister chromatid separation def: "A cellular process phenotype in which mitotic sister chromatid separation is abnormal. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [GO:0051306, PomBase:mah] synonym: "abnormal mitotic chromosome separation" EXACT [PomBase:mah] synonym: "abnormal sister chromatid separation during mitosis" EXACT [PomBase:mah] synonym: "abnormal sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal sister chromatid separation during vegetative growth" EXACT [PomBase:mah] synonym: "aneuploidy" RELATED [PomBase:vw] synonym: "mitotic chromosome missegregation" RELATED [PomBase:vw] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-11-11T01:51:59Z [Term] id: FYPO:0000671 name: abnormal rDNA separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation at the rDNA repeat regions is abnormal." [PomBase:mah] synonym: "abnormal mitotic sister chromatid separation at rDNA" EXACT [PomBase:mah] synonym: "abnormal rDNA separation during mitosis" EXACT [PomBase:mah] synonym: "abnormal rDNA separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal rDNA separation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ribosomal DNA separation" EXACT [PomBase:mah] synonym: "abnormal segregation of nucleolar rDNA" RELATED [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2011-11-11T01:59:59Z [Term] id: FYPO:0000672 name: normal cell morphology def: "A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure)." [PomBase:mah] synonym: "cellular morphology: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0007723 ! normal cellular physical quality phenotype created_by: midori creation_date: 2011-11-11T02:51:12Z [Term] id: FYPO:0000673 name: normal septum assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "normal septation" BROAD [GO:0000917, PomBase:mah] synonym: "normal septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septum assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-11-11T02:53:07Z [Term] id: FYPO:0000674 name: normal cell population growth at high temperature def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a high temperature." [PomBase:mah] synonym: "heat sensitivity: normal" RELATED [SGD:phenotype_annotation] synonym: "normal growth at high temperature" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth at high temperature" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2011-11-11T02:55:04Z [Term] id: FYPO:0000675 name: abnormal protein targeting during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting is abnormal." [PomBase:mah] comment: Encompasses both targeting of proteins to a particular location where they are not normally found and decreased or no targeting of proteins normally found in the location. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein targeting during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport during vegetative growth created_by: midori creation_date: 2011-11-11T03:24:12Z [Term] id: FYPO:0000676 name: abnormal protein targeting to vacuole def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole is abnormal." [PomBase:mah] comment: Encompasses both targeting of proteins to the vacuole where they are not normally found and decreased or no targeting of proteins normally found in the vacuole. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein targeting to vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein targeting to vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vacuolar protein sorting" EXACT [PomBase:mah] is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth is_a: FYPO:0000675 ! abnormal protein targeting during vegetative growth created_by: midori creation_date: 2011-11-11T03:25:01Z [Term] id: FYPO:0000677 name: abnormal protein localization to prospore membrane def: "A transport phenotype in which protein localization to the prospore membrane is abnormal." [PomBase:mah] comment: Encompasses both targeting of proteins to the prospore membrane where they are not normally found and decreased or no targeting of proteins normally found in the prospore membrane. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to prospore membrane" EXACT [PomBase:mah] synonym: "abnormal protein localization to forespore membrane" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2011-11-29T05:16:27Z [Term] id: FYPO:0000678 name: unequal homologous chromosome segregation def: "A cellular process phenotype in which homologous chromosomes are not segregated equally to the two spindle poles in the first meiotic nuclear division. For example, both homologs of one or more chromosomes may be segregated to the same spindle pole." [PomBase:mah] synonym: "aneuploidy" RELATED [PomBase:vw] synonym: "chromosome non-disjunction at meiosis I" RELATED [PomBase:vw] synonym: "chromosome nondisjunction at meiosis I" RELATED [PomBase:mah] synonym: "chromosome nondisjunction during meiosis I" RELATED [PomBase:mah] synonym: "impaired disjunction of homologous chromosomes" EXACT [] synonym: "impaired homologous chromosome disjunction" EXACT [] synonym: "meiosis I nondisjunction" RELATED [PomBase:mah] synonym: "unequal chromosome disjunction during meiosis I" EXACT [PomBase:mah] synonym: "unequal homologous chromosome disjunction" EXACT [PomBase:mah] is_a: FYPO:0000925 ! unequal meiotic chromosome segregation is_a: FYPO:0004159 ! abnormal homologous chromosome segregation created_by: midori creation_date: 2011-11-29T05:44:25Z [Term] id: FYPO:0000679 name: developmental process phenotype def: "A phenotype that affects a developmental process." [PomBase:mah] synonym: "fission yeast developmental process phenotype" EXACT [PomBase:mah] is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-11-29T06:02:16Z [Term] id: FYPO:0000680 name: abnormal ascus development def: "A developmental process phenotype in which ascus development is abnormal." [PomBase:mah] is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-11-29T06:03:31Z [Term] id: FYPO:0000681 name: abnormal sporulation resulting in formation of two-spore ascus def: "A sporulation phenotype that results in the formation of an ascus that has abnormal morphology and contains two diploid spores." [PMID:11156975, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation of two-spore ascus" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of two-spore asci" EXACT [PomBase:mah] is_a: FYPO:0003066 ! abnormal sporulation resulting in formation of ascus with fewer than four spores created_by: midori creation_date: 2011-12-01T01:29:02Z [Term] id: FYPO:0000682 name: abnormal regulation of molecular function def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a molecular function is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal regulation of molecular function during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of molecular function during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-12-01T01:43:05Z [Term] id: FYPO:0000683 name: constitutive catalytic activity def: "A regulation phenotype in which the basal activity of an enzyme is increased relative to normal. Basal enzyme activity is the activity observed in the absence of a regulator. Abnormally elevated basal activity may or may not reach the levels observed in the normal activated state." [PomBase:al, PomBase:mah] synonym: "constitutive catalytic activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "constitutive catalytic activity during vegetative growth" EXACT [PomBase:mah] synonym: "constitutive enzymatic activity" EXACT [PomBase:mah] synonym: "constitutively active enzyme" RELATED [PomBase:mah] is_a: FYPO:0000654 ! catalytic activity phenotype relationship: output_of FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2011-12-01T01:51:53Z [Term] id: FYPO:0000684 name: decreased cell population growth on glycerol carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol as the carbon source." [PomBase:al, PomBase:mah] comment: Note that trace amounts of another carbon source are usually required for S. pombe growth on glycerol; yeast extract-based rich medium supplies the trace substance, but minimal medium must be supplemented. It is therefore important to annotate the growth medium as an experimental condition when using this term. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on glycerol carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on glycerol carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on glycerol carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on glycerol carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2011-12-01T04:41:03Z [Term] id: FYPO:0000685 name: obsolete transcriptional response to pheromone at decreased pheromone level def: "OBSOLETE. A cellular response phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter occurs at a lower level of pheromone than normal." [PomBase:mah] comment: This term was made obsolete because it has a confusing name and represents a non-useful distinction. synonym: "increased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "increased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "positive regulation of transcription from RNA polymerase II promoter by pheromones at decreased pheromone level" EXACT [GO:0007329, PomBase:mah] synonym: "sensitive to pheromone" RELATED [PomBase:al, PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-12-01T04:46:17Z [Term] id: FYPO:0000686 name: normal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity def: "A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000687 name: abnormal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity def: "A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000688 name: decreased peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity def: "A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is decreased." [PomBase:mah] synonym: "reduced peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity" EXACT [PomBase:mah] is_a: FYPO:0000687 ! abnormal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000689 name: abnormal oxidoreductase activity def: "A molecular function phenotype in which the observed rate of an oxidoreductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000690 name: decreased oxidoreductase activity def: "A molecular function phenotype in which the observed rate of an oxidoreductase activity is decreased." [PomBase:mah] synonym: "reduced oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000691 name: normal DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000692 name: abnormal DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000693 name: decreased DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is decreased." [PomBase:mah] synonym: "reduced DNA-1,N6-ethenoadenine N-glycosylase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000692 ! abnormal DNA-1,N6-ethenoadenine N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000694 name: abolished DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which DNA-1,N6-ethenoadenine N-glycosylase activity is absent." [PomBase:mah] synonym: "DNA-1,N6-ethenoadenine N-glycosylase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000692 ! abnormal DNA-1,N6-ethenoadenine N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000695 name: increased DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000692 ! abnormal DNA-1,N6-ethenoadenine N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000696 name: normal DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000697 name: abnormal DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000698 name: decreased DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is decreased." [PomBase:mah] synonym: "reduced DNA-7-methylguanine glycosylase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000697 ! abnormal DNA-7-methylguanine glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000699 name: abolished DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which DNA-7-methylguanine glycosylase activity is absent." [PomBase:mah] synonym: "DNA-7-methylguanine glycosylase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000697 ! abnormal DNA-7-methylguanine glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000700 name: increased DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000697 ! abnormal DNA-7-methylguanine glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000701 name: abolished DNA damage checkpoint override in response to caffeine def: "A cellular response phenotype in which caffeine does not override the DNA damage checkpoint (as it does in wild type cells), allowing mitotic cell cycle arrest to occur." [PMID:10224243, PomBase:mah] synonym: "abolished DNA damage checkpoint override in response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "caffeine-mediated DNA damage checkpoint override abolished" EXACT [GOC:mah, GOC:vw] synonym: "DNA damage checkpoint override in response to caffeine abolished" EXACT [PomBase:mah] synonym: "DNA damage checkpoint override in response to caffeine abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000207 ! abnormal cellular response to caffeine is_a: FYPO:0001704 ! abnormal mitotic cell cycle checkpoint created_by: midori creation_date: 2011-12-05T01:59:12Z [Term] id: FYPO:0000702 name: protein-protein interaction phenotype def: "A phenotype that protein affects the binding of one protein to another. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast protein binding phenotype" EXACT [PomBase:mah] synonym: "fission yeast protein-protein interaction phenotype" EXACT [PomBase:mah] synonym: "protein binding phenotype" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2011-12-05T02:24:49Z [Term] id: FYPO:0000703 name: normal protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is tested in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal protein binding" EXACT [PomBase:mah] is_a: FYPO:0000702 ! protein-protein interaction phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2011-12-05T02:25:15Z [Term] id: FYPO:0000704 name: abnormal protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal protein binding" EXACT [PomBase:mah] is_a: FYPO:0000702 ! protein-protein interaction phenotype is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2011-12-05T02:25:58Z [Term] id: FYPO:0000705 name: abolished protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another does not occur. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished protein binding" EXACT [PomBase:mah] synonym: "protein binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2011-12-05T02:26:17Z [Term] id: FYPO:0000706 name: normal molecular function def: "A phenotype in which a specific molecular function is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2011-12-05T03:06:23Z [Term] id: FYPO:0000707 name: abnormal molecular function def: "A phenotype in which a specific molecular function is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000652 ! molecular function phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-12-05T03:09:24Z [Term] id: FYPO:0000708 name: decreased mating efficiency def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal." [PMID:15300681, PMID:16598689, PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). synonym: "mating efficiency: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced mating efficiency" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-12-05T04:26:20Z [Term] id: FYPO:0000709 name: decreased cell population growth during nitrogen starvation alt_id: FYPO:0002124 def: "A cell growth phenotype in which cell population growth is decreased relative to normal under nitrogen starvation conditions, such as in nitrogen-deficient minimal medium." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to nitrogen starvation in culture. If you have assayed the response to nitrogen starvation at the subcellular or molecular level, consider annotating to 'abnormal cellular response to nitrogen starvation' (FYPO:0000152). Also note that this term can be used for any circumstances in which cells are starved for nitrogen. Cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation, but this term is not restricted to G0. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased cell population growth during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased cell population growth during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased cell population growth in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "hypersensitive to nitrogen starvation" RELATED [PomBase:mah] synonym: "reduced cell population growth during nitrogen starvation" RELATED [PomBase:mah] synonym: "sensitive to nitrogen depletion" RELATED [PomBase:vw] synonym: "sensitive to nitrogen deprivation" RELATED [PomBase:vw] synonym: "sensitive to nitrogen starvation" RELATED [PomBase:mah] synonym: "slow cell population growth during nitrogen starvation" NARROW [PomBase:mah] synonym: "slow cell population growth in nitrogen-deficient minimal medium" RELATED [PomBase:al, PomBase:mah] synonym: "slow growth during nitrogen starvation" BROAD [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth created_by: midori creation_date: 2011-12-05T04:43:53Z [Term] id: FYPO:0000710 name: abnormal mitotic cell cycle arrest in response to nitrogen starvation def: "A cellular process phenotype in which mitotic cell cycle arrest in response to nitrogen starvation, which normally occurs in G1 phase, is abnormal." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal mitotic cell cycle arrest in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal mitotic cell cycle arrest in response to nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000152 ! abnormal cellular response to nitrogen starvation is_a: FYPO:0001026 ! abnormal occurrence of normal mitotic cell cycle arrest created_by: midori creation_date: 2011-12-06T12:15:03Z [Term] id: FYPO:0000711 name: decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but its occurrence is decreased." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "decreased cell cycle arrest in mitotic G1 phase during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased mitotic cell cycle arrest in G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] synonym: "reduced cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000710 ! abnormal mitotic cell cycle arrest in response to nitrogen starvation is_a: FYPO:0005097 ! abnormal cell cycle arrest in mitotic G1 phase created_by: midori creation_date: 2011-12-06T12:15:32Z [Term] id: FYPO:0000712 name: delayed onset of cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but begins later than normal." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "delayed cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed onset of cell cycle arrest in mitotic G1 phase during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed onset of cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "delayed onset of cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "delayed onset of mitotic cell cycle arrest in G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed onset of mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed onset of nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] is_a: FYPO:0000711 ! decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation created_by: midori creation_date: 2011-12-06T12:16:53Z [Term] id: FYPO:0000713 name: abnormal cellular response to starvation def: "A stress response phenotype in which the response to starvation for one or more nutrients is abnormal." [PomBase:mah] synonym: "abnormal cellular response to depletion" EXACT [PomBase:vw] synonym: "abnormal cellular response to deprivation" EXACT [PomBase:vw] is_a: FYPO:0000162 ! abnormal cellular response to stress created_by: midori creation_date: 2011-12-06T12:25:40Z [Term] id: FYPO:0000714 name: sensitive to leptomycin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to leptomycin B. Cells stop growing (and may die) at a concentration of leptomycin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to leptomycin B" EXACT [PomBase:mah] synonym: "sensitive to leptomycin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to leptomycin B during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to LMB" EXACT [CHEBI:52646, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000715 name: sensitive to K-252a def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to K-252a. Cells stop growing (and may die) at a concentration of K-252a that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to K-252a" EXACT [PomBase:mah] synonym: "sensitive to K-252a during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to K-252a during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000716 name: sensitive to valinomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to valinomycin. Cells stop growing (and may die) at a concentration of valinomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to valinomycin" EXACT [PomBase:mah] synonym: "sensitive to valinomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to valinomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000717 name: sensitive to actinomycin D def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to actinomycin D. Cells stop growing (and may die) at a concentration of actinomycin D that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to actinomycin D" EXACT [PomBase:mah] synonym: "sensitive to actinomycin D during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to actinomycin D during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000719 name: normal fatty acid synthase activity def: "A molecular function phenotype in which the observed rate of fatty acid synthase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal FAS activity" EXACT [PomBase:al, PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-06T01:43:30Z [Term] id: FYPO:0000720 name: abnormal fatty acid synthase activity def: "A molecular function phenotype in which the observed rate of fatty acid synthase activity is abnormal." [PomBase:mah] synonym: "abnormal FAS activity" EXACT [PomBase:al, PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-06T01:57:58Z [Term] id: FYPO:0000721 name: abnormal cellular response to pH def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a pH stimulus is abnormal." [PomBase:mah] synonym: "abnormal cellular response to pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to pH during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2011-12-06T02:45:18Z [Term] id: FYPO:0000722 name: sensitive to acidity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acidic pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow." [PomBase:mah] comment: In chemistry, acid pH is below 7.0. This term, however, is most useful for annotating phenotypes observed at any pH lower than that of standard fission yeast media, about 5.8. Also see 'sensitive to low pH' (FYPO:0001989). synonym: "acid pH resistance: decreased" RELATED [SGD:phenotype_annotation] synonym: "decreased growth during cellular response to acidity" EXACT [PomBase:mah] synonym: "decreased growth on acidic medium" RELATED [PomBase:al] synonym: "decreased vegetative cell population growth during cellular response to acidity" EXACT [PomBase:mah] synonym: "hypersensitive to acidity" EXACT [PomBase:mah] synonym: "sensitive to acidity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to acidity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2011-12-06T02:47:00Z [Term] id: FYPO:0000723 name: sensitive to alkalinity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to alkaline pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow." [PomBase:mah] comment: In chemistry, alkaline pH is over 7.0. This term, however, is most useful for annotating phenotypes observed at any pH higher than that of standard fission yeast media, about 5.8. Also see 'sensitive to high pH' (FYPO:0001987). synonym: "alkaline pH resistance: decreased" RELATED [SGD:phenotype_annotation] synonym: "decreased growth during cellular response to alkalinity" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to alkalinity" EXACT [PomBase:mah] synonym: "hypersensitive to alkalinity" EXACT [PomBase:mah] synonym: "sensitive to alkalinity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to alkalinity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2011-12-06T02:48:18Z [Term] id: FYPO:0000724 name: resistance to N-methyl-N'-nitro-N-nitrosoguanidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N-methyl-N'-nitro-N-nitrosoguanidine than normal." [PomBase:mah] synonym: "resistance to methylnitronitrosoguanidine" EXACT [CHEBI:21759] synonym: "resistance to N-methyl-N'-nitro-N-nitrosoguanidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to N-methyl-N'-nitro-N-nitrosoguanidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to MNNG" EXACT [CHEBI:21759] synonym: "resistant to N-methyl-N'-nitro-N-nitrosoguanidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-12-06T04:17:30Z [Term] id: FYPO:0000725 name: resistance to methyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methyl methanesulfonate than normal." [PomBase:mah] synonym: "resistance to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "resistance to MMS" EXACT [PomBase:mah] synonym: "resistant to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2011-12-07T11:28:32Z [Term] id: FYPO:0000726 name: sensitive to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxidative stress." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to oxidative stress in culture. If you have assayed the response to oxidative stress at the subcellular or molecular level, consider annotating to 'abnormal cellular response to oxidative stress during vegetative growth' (FYPO:0001340). synonym: "decreased growth during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "hypersensitive to oxidative stress" EXACT [PomBase:mah] synonym: "oxidative stress resistance: decreased" RELATED [SGD:phenotype_annotation] synonym: "sensitive to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to oxidative stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2011-12-07T01:17:37Z [Term] id: FYPO:0000727 name: abnormal actin filament organization during vegetative growth def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of cytoskeletal structures comprising actin filaments does not occur normally." [GO:0007015, PomBase:mah] synonym: "abnormal actin filament organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin filament organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of actin filament localization during vegetative growth" NARROW [GO:0007015] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2011-12-07T02:53:31Z [Term] id: FYPO:0000728 name: abnormal actin cortical patch assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch assembly is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin patch assembly" EXACT [PomBase:mah] synonym: "abnormal F-actin patch assembly" EXACT [PomBase:mah] is_a: FYPO:0000790 ! abnormal actin cortical patch organization created_by: midori creation_date: 2011-12-07T03:02:33Z [Term] id: FYPO:0000729 name: delayed onset of actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring assembly begins later than normal. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins." [PomBase:mah] synonym: "delayed actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "delayed onset of actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:vw] synonym: "delayed onset of contractile ring assembly" EXACT [PomBase:mah] synonym: "delayed onset of cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "delayed onset of cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "delayed onset of cytokinetic ring formation" RELATED [PomBase:vw] synonym: "delayed onset of mitotic contractile ring assembly" EXACT [PomBase:vw] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly created_by: midori creation_date: 2011-12-07T04:50:03Z [Term] id: FYPO:0000730 name: long spindle def: "A spindle phenotype in which the spindle is longer than normal." [PomBase:mah] synonym: "elongated spindle" EXACT [PomBase:mah] synonym: "increased spindle length" EXACT [PomBase:mah] synonym: "long spindles" EXACT [PomBase:mah] is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2011-12-07T04:51:57Z [Term] id: FYPO:0000731 name: abnormal protein localization to medial cortex during vegetative growth def: "A cell phenotype in which the localization of a protein to the medial cortex is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortex during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "abnormal protein localization to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001373 ! abnormal protein localization to medial cortex created_by: midori creation_date: 2011-12-07T05:16:57Z [Term] id: FYPO:0000732 name: short bipolar mitotic spindle def: "A spindle phenotype in which the mitotic spindle is shorter than normal." [PomBase:mah] comment: Note that short mitotic spindles are usually not parallel to the long axis of the cell, because short spindle formation takes place before spindle orientation is established (see GO:0000132). synonym: "decreased mitotic spindle length" EXACT [PomBase:mah] synonym: "short mitotic spindle" EXACT [PomBase:vw] synonym: "short mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "short mitotic spindles" EXACT [PomBase:mah] synonym: "short spindle during mitosis" EXACT [PomBase:mah] synonym: "short spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000130 ! short spindle is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle created_by: midori creation_date: 2012-01-11T11:30:01Z [Term] id: FYPO:0000733 name: long mitotic spindle def: "A spindle phenotype in which the mitotic spindle is longer than normal." [PomBase:mah] synonym: "elongated mitotic spindle" EXACT [PomBase:mah] synonym: "increased mitotic spindle length" EXACT [PomBase:vw] synonym: "long bipolar mitotic spindle" EXACT [PomBase:vw] synonym: "long mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "long mitotic spindles" EXACT [PomBase:mah] synonym: "long spindle during mitosis" EXACT [PomBase:mah] synonym: "long spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000730 ! long spindle is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle created_by: midori creation_date: 2012-01-11T11:30:01Z [Term] id: FYPO:0000734 name: abnormal meiotic spindle def: "A physical cellular phenotype in which the structure of the meiotic spindle is abnormal." [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle created_by: midori creation_date: 2012-01-11T11:30:13Z [Term] id: FYPO:0000735 name: short meiotic spindle def: "A spindle phenotype in which the meiotic spindle is shorter than normal." [PomBase:mah] synonym: "decreased meiotic spindle length" EXACT [PomBase:mah] synonym: "short meiotic spindles" EXACT [PomBase:mah] synonym: "short spindle during meiosis" EXACT [PomBase:mah] is_a: FYPO:0000130 ! short spindle is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2012-01-11T11:30:48Z [Term] id: FYPO:0000736 name: long meiotic spindle def: "A spindle phenotype in which the meiotic spindle is longer than normal." [PomBase:mah] synonym: "elongated meiotic spindle" EXACT [PomBase:mah] synonym: "increased meiotic spindle length" EXACT [PomBase:mah] synonym: "long meiotic spindles" EXACT [PomBase:mah] is_a: FYPO:0000730 ! long spindle is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2012-01-11T11:30:48Z [Term] id: FYPO:0000737 name: abnormal meiotic spindle assembly def: "A cellular process phenotype in which assembly of the meiotic spindle is abnormal." [PomBase:mah] synonym: "abnormal spindle assembly involved in meiosis" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0000119 ! abnormal spindle assembly relationship: has_output FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2012-01-11T11:42:55Z [Term] id: FYPO:0000739 name: cellular pigment accumulation phenotype def: "A cellular process phenotype that affects the occurrence of pigment accumulation in a cell." [PomBase:mah] comment: Note that this term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "cellular pigment accumulation phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cellular pigment accumulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast cellular pigment accumulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-01-11T12:21:14Z [Term] id: FYPO:0000740 name: normal cellular pigment accumulation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that normal cells do not accumulate detectable levels of any pigment; also note that this term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "normal cellular pigment accumulation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular pigment accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000739 ! cellular pigment accumulation phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-01-11T12:27:26Z [Term] id: FYPO:0000741 name: increased cellular pigment accumulation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased." [PomBase:mah] comment: Note that normal cells do not accumulate detectable levels of any pigment; for this reason, FYPO does not include separate terms for 'increased' and 'abnormal' pigment accumulation. Also note that pigment accumulates in the vacuole. This term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "abnormal cellular pigment accumulation" EXACT [PomBase:mah] synonym: "altered colony color" RELATED [PomBase:al, PomBase:mah] synonym: "altered colony colour" RELATED [PomBase:al, PomBase:mah] synonym: "increased cellular pigment accumulation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular pigment accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000739 ! cellular pigment accumulation phenotype is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-01-11T12:29:34Z [Term] id: FYPO:0000742 name: abnormal protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in actin cortical patches and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actin cortical patch" EXACT [PomBase:mah] synonym: "abnormal protein localization to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to actin patch" EXACT [PomBase:mah] synonym: "abnormal protein localization to F-actin patch" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-01-11T12:45:30Z [Term] id: FYPO:0000743 name: abnormal actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization is abnormal. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell." [PMID:21620704, PomBase:mah] synonym: "abnormal actin cortical patch internalisation" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch internalization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin patch internalization" EXACT [PomBase:vw] synonym: "abnormal actin patch internalization" EXACT [PomBase:mah] synonym: "abnormal F-actin patch internalization" EXACT [PomBase:mah] is_a: FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth created_by: midori creation_date: 2012-01-11T12:50:31Z [Term] id: FYPO:0000744 name: normal protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to actin cortical patch" EXACT [PomBase:mah] synonym: "normal protein localization to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to actin patch" EXACT [PomBase:mah] synonym: "normal protein localization to F-actin patch" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2012-01-11T01:47:11Z [Term] id: FYPO:0000745 name: delayed onset of actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization begins later than normal. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell." [PMID:21620704, PomBase:mah] synonym: "delayed actin cortical patch internalization" EXACT [PomBase:mah] synonym: "delayed onset of abnormal actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of actin cortical patch internalisation" EXACT [PomBase:mah] synonym: "delayed onset of actin cortical patch internalization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of actin patch internalization" EXACT [PomBase:mah] synonym: "delayed onset of F-actin patch internalization" EXACT [PomBase:mah] is_a: FYPO:0000743 ! abnormal actin cortical patch internalization created_by: midori creation_date: 2012-01-11T01:57:25Z [Term] id: FYPO:0000746 name: abolished actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization does not occur. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell." [PMID:21620704, PomBase:mah] synonym: "abolished actin cortical patch internalisation" EXACT [PomBase:mah] synonym: "abolished actin cortical patch internalization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "abolished actin patch internalization" EXACT [PomBase:mah] synonym: "abolished F-actin patch internalization" EXACT [PomBase:mah] synonym: "actin cortical patch internalization abolished" EXACT [PomBase:mah] is_a: FYPO:0000743 ! abnormal actin cortical patch internalization created_by: midori creation_date: 2012-01-11T01:57:40Z [Term] id: FYPO:0000747 name: growth auxotrophic for adenine def: "Auxotrophy in which a cell is unable to synthesize adenine, and therefore requires adenine in the medium for vegetative cell growth." [PomBase:mah] synonym: "adenine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for adenine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for adenine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2012-01-11T01:59:50Z [Term] id: FYPO:0000748 name: sensitive to mercury def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercury ions. Cells stop growing (and may die) at a concentration of mercury ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mercury" EXACT [PomBase:mah] synonym: "sensitive to mercury during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to mercury during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to mercury ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-11T02:03:34Z [Term] id: FYPO:0000749 name: sensitive to selenite ion def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to selenite ((SeO3)2-) ions. Cells stop growing (and may die) at a concentration of selenite ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to selenite ion" EXACT [PomBase:mah] synonym: "sensitive to selenite ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to selenite ion during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to selenite ions" EXACT [PomBase:mah] synonym: "sensitive to selenium" RELATED [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-11T02:09:20Z [Term] id: FYPO:0000750 name: sensitive to silver ions def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to silver ions. Cells stop growing (and may die) at a concentration of silver ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to silver ions" EXACT [PomBase:mah] synonym: "sensitive to silver" RELATED [PomBase:mah] synonym: "sensitive to silver ions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to silver ions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-11T02:23:17Z [Term] id: FYPO:0000751 name: sensitive to nickel def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nickel ions. Cells stop growing (and may die) at a concentration of nickel ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nickel" EXACT [PomBase:mah] synonym: "sensitive to nickel during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nickel during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to nickel ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-11T02:23:37Z [Term] id: FYPO:0000752 name: resistance to selenate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal." [PomBase:mah] synonym: "resistance to selenate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to selenate during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to selenate ions" EXACT [PomBase:mah] synonym: "resistant to selenate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-01-11T02:24:43Z [Term] id: FYPO:0000753 name: normal glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-01-11T02:33:09Z [Term] id: FYPO:0000754 name: abnormal glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-01-11T02:34:18Z [Term] id: FYPO:0000755 name: decreased glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is decreased." [PomBase:mah] synonym: "reduced glutathione gamma-glutamylcysteinyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000754 ! abnormal glutathione gamma-glutamylcysteinyltransferase activity created_by: midori creation_date: 2012-01-11T02:34:31Z [Term] id: FYPO:0000756 name: sensitive to bafilomycin A1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bafilomycin A1. Cells stop growing (and may die) at a concentration of bafilomycin A1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bafilomycin A1" EXACT [PomBase:mah] synonym: "sensitive to bafilomycin A" RELATED [PomBase:mah] synonym: "sensitive to bafilomycin A1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to bafilomycin A1 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-12T11:24:11Z [Term] id: FYPO:0000757 name: sensitive to nigericin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nigericin. Cells stop growing (and may die) at a concentration of nigericin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nigericin" EXACT [PomBase:mah] synonym: "sensitive to nigericin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nigericin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-12T11:25:08Z [Term] id: FYPO:0000758 name: sensitive to bismuth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bismuth ions. Cells stop growing (and may die) at a concentration of bismuth that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bismuth" EXACT [PomBase:mah] synonym: "sensitive to bismuth during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to bismuth during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to bismuth ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-18T03:00:13Z [Term] id: FYPO:0000759 name: sensitive to lead def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lead ions. Cells stop growing (and may die) at a concentration of lead ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to lead" EXACT [PomBase:mah] synonym: "sensitive to lead during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to lead during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to lead ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-01-18T03:00:32Z [Term] id: FYPO:0000760 name: normal mating def: "A cellular process phenotype in which conjugation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal conjugation" EXACT [PomBase:mah] synonym: "normal conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "normal zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0000301 ! mating phenotype created_by: midori creation_date: 2012-01-18T03:02:59Z [Term] id: FYPO:0000761 name: increased conjugation frequency def: "A cell population phenotype in which a larger than normal proportion of cells in the population undergoes conjugation." [PomBase:mah] comment: Note that this term refers specifically to conjugation, whereas experiments that measure mating efficiency often do so by counting zygotes plus asci, sometimes also including spores. For such experiments, we recommend using 'increased mating efficiency' (FYPO:0001043). synonym: "increased conjugation efficiency" RELATED [PomBase:mah] synonym: "increased mating frequency" EXACT [PomBase:mah] synonym: "increased occurrence of conjugation" EXACT [PomBase:mah] synonym: "increased zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-01-18T03:03:19Z [Term] id: FYPO:0000763 name: resistance to cadmium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cadmium ions than normal." [PomBase:mah] synonym: "resistance to cadmium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cadmium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to cadmium ion" EXACT [PomBase:mah] synonym: "resistance to cadmium ions" EXACT [PomBase:mah] synonym: "resistant to cadmium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000764 name: resistance to cycloheximide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cycloheximide than normal." [PomBase:mah] synonym: "resistance to cycloheximide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cycloheximide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to cycloheximide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000765 name: resistance to leptomycin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of leptomycin B than normal." [PomBase:mah] synonym: "resistance to leptomycin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to leptomycin B during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to leptomycin B" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000766 name: resistance to N-ethylmaleimide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N-ethylmaleimide than normal." [PomBase:mah] synonym: "resistance to N-ethylmaleimide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to N-ethylmaleimide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to N-ethylmaleimide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000767 name: resistance to staurosporine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of staurosporine than normal." [PomBase:mah] synonym: "resistance to staurosporine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to staurosporine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to staurosporine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000768 name: resistance to valinomycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of valinomycin than normal." [PomBase:mah] synonym: "resistance to valinomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to valinomycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to valinomycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000769 name: abnormal nuclear envelope morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is abnormal." [PomBase:mah] comment: Note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "abnormal nuclear envelope morphology during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal nuclear membrane morphology" NARROW [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth is_a: FYPO:0000353 ! abnormal endomembrane system morphology relationship: output_of FYPO:0000815 ! abnormal nuclear envelope organization created_by: midori creation_date: 2012-02-09T03:51:02Z [Term] id: FYPO:0000770 name: branched nuclear inner membrane def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear inner membrane forms branched structures that extend into the nuclear lumen." [PMID:21880100, PomBase:mah] synonym: "branched nuclear inner membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched nuclear inner membrane during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2012-02-09T03:54:48Z [Term] id: FYPO:0000771 name: normal nuclear pore localization def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is normal (i.e. indistinguishable from wild type), resulting in a normal spatial arrangement of nuclear pores within the nuclear envelope." [PomBase:mah] synonym: "normal NPC localization" EXACT [PomBase:mah] synonym: "normal nuclear pore complex localization" EXACT [PomBase:mah] synonym: "normal nuclear pore distribution" EXACT [GO:0051664] synonym: "normal nuclear pore localisation" EXACT [PomBase:mah] synonym: "normal nuclear pore localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear pore localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2012-02-09T04:03:08Z [Term] id: FYPO:0000772 name: perforated nuclear envelope def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which perforations or gaps (other than nuclear pores) are present in the nuclear envelope." [PomBase:mah] synonym: "disrupted nuclear envelope" RELATED [PomBase:mah] synonym: "disrupted nuclear membrane" RELATED [PomBase:mah] synonym: "gapped nuclear envelope" EXACT [PomBase:mah] synonym: "perforated nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "perforated nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "perforated nuclear membrane" RELATED [PomBase:mah] synonym: "permeabilized nucleus during mitosis" EXACT [PMID:32848252] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2012-02-09T04:12:08Z [Term] id: FYPO:0000773 name: abnormal pre-replicative complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pre-replicative complex assembly is abnormal." [PomBase:mah] synonym: "abnormal pre-RC assembly" EXACT [PomBase:mah] synonym: "abnormal pre-replicative complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal pre-replicative complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal pre-replicative complex formation" EXACT [GO:0006267, PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2012-02-09T04:18:40Z [Term] id: FYPO:0000774 name: decreased pre-replicative complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of pre-replicative complex assembly is decreased." [PomBase:mah] synonym: "decreased pre-RC assembly" EXACT [PomBase:mah] synonym: "decreased pre-replicative complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased pre-replicative complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pre-replicative complex formation" EXACT [GO:0006267, PomBase:mah] synonym: "reduced pre-replicative complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000773 ! abnormal pre-replicative complex assembly created_by: midori creation_date: 2012-02-09T04:26:56Z [Term] id: FYPO:0000775 name: abnormal protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2012-02-09T04:32:41Z [Term] id: FYPO:0000776 name: normal protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth is_a: FYPO:0004422 ! normal protein phosphorylation created_by: midori creation_date: 2012-02-09T04:33:28Z [Term] id: FYPO:0000777 name: abnormal double-strand break repair during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is abnormal." [PomBase:mah] synonym: "abnormal double-strand break repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal DSB repair during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000188 ! abnormal DNA repair during vegetative growth created_by: midori creation_date: 2012-02-09T04:35:48Z [Term] id: FYPO:0000778 name: delayed onset of double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair begins later than normal." [PomBase:mah] synonym: "delayed double-strand break repair" EXACT [PomBase:mah] synonym: "delayed onset of double-strand break repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2012-02-09T04:37:10Z [Term] id: FYPO:0000779 name: inviable elongated vegetative cell with central constriction alt_id: FYPO:0000018 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is longer than normal and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells." [PomBase:mah, PomBase:vw] comment: Note that cell with this phenotype, often called dumbbell-shaped, are usually also elongated. The distinction between this phenotype and swollen elongated cells (FYPO:0001429) is that dumbbell-shaped cells have a constriction along the long axis, whereas swollen elongated cells do not. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cell morphology, elongated dumbbell" RELATED [PomBase:mah] synonym: "cell morphology, long dumbbell" RELATED [PomBase:vw] synonym: "elongated dumbbell morphology" RELATED [PomBase:mah] synonym: "inviable elongated cell with central constriction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated cell with central constriction during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated dumbbell-shaped vegetative cell" RELATED [PomBase:vw] synonym: "inviable elongated swollen vegetative cell with constricted region at cell division site" EXACT [PomBase:vw] synonym: "lethal; elongated vegetative cell with central constriction" EXACT [PomBase:mah] is_a: FYPO:0000950 ! elongated aseptate vegetative cell is_a: FYPO:0005115 ! elongated vegetative cell with central constriction created_by: midori creation_date: 2012-02-13T12:48:01Z [Term] id: FYPO:0000780 name: increased transcription during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'increased RNA level' (FYPO:0000825). synonym: "increased transcription during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002875 ! increased transcription is_a: FYPO:0004064 ! abnormal transcription during vegetative growth is_a: FYPO:0004527 ! abnormal regulation of transcription during vegetative growth relationship: has_output FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-02-28T03:56:27Z [Term] id: FYPO:0000781 name: decreased transcription during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). synonym: "decreased transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002876 ! decreased transcription is_a: FYPO:0004064 ! abnormal transcription during vegetative growth is_a: FYPO:0004527 ! abnormal regulation of transcription during vegetative growth relationship: has_output FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-02-28T03:57:44Z [Term] id: FYPO:0000782 name: mislocalized protein during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is observed in a particular location where it is not normally found." [PomBase:mah] comment: The difference between this term and 'abnormal protein localization' (FYPO:0000443) is that 'mislocalized protein' describes a protein that is observed in a place where it is not normally found, whereas 'abnormal protein localization' additionally encompasses the absence of protein from a place where it is normally found. FYPO:0000782 can therefore be used in any case where a protein is in a different location in a mutant compared to wild type, whereas additional information is usually required to support annotation to FYPO:0000443 or its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized protein during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003452 ! mislocalized protein is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth relationship: output_of FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2012-02-29T12:48:27Z [Term] id: FYPO:0000783 name: protein mislocalized to cytoplasm during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the cytoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to cytoplasm during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalised to cytoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth is_a: FYPO:0004842 ! protein mislocalized to cytoplasm created_by: midori creation_date: 2012-02-29T12:49:47Z [Term] id: FYPO:0000784 name: protein mislocalized to nucleus during vegetative growth alt_id: FYPO:0001251 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleus is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleus during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth is_a: FYPO:0003453 ! protein mislocalized to nucleus created_by: midori creation_date: 2012-02-29T12:50:40Z [Term] id: FYPO:0000785 name: sensitive to formamide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to formamide. Cells stop growing (and may die) at a concentration of formamide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to formamide" EXACT [PomBase:mah] synonym: "sensitive to formamide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to formamide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-02-29T01:30:18Z [Term] id: FYPO:0000786 name: increased plasmid loss def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which plasmids are lost at a higher frequency than normal. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation." [PomBase:mah] comment: Note that in budding yeast, increased plasmid loss is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. synonym: "increased plasmid loss during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased plasmid loss during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2012-02-29T01:39:20Z [Term] id: FYPO:0000787 name: abnormal histone H3-K9 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me3 during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2012-02-29T01:43:54Z [Term] id: FYPO:0000788 name: abnormal histone H3-K14 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K14 acetylation during vegetative growth" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2012-02-29T01:46:18Z [Term] id: FYPO:0000789 name: sensitive to 1-NA-PP1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1-NA-PP1. Cells stop growing (and may die) at a concentration of 1-NA-PP1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 1-NA-PP1" EXACT [PomBase:mah] synonym: "sensitive to 1-NA-PP1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 1-NA-PP1 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to 1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine" EXACT [CHEBI:52310, PomBase:mah] synonym: "sensitive to 4-amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine" EXACT [CHEBI:52310, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-02-29T01:53:55Z [Term] id: FYPO:0000790 name: abnormal actin cortical patch organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch." [GO:0044396, PomBase:mah] synonym: "abnormal actin cortical patch organisation" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin patch organization" EXACT [PomBase:mah] synonym: "abnormal F-actin patch organization" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2012-02-29T03:11:58Z [Term] id: FYPO:0000791 name: abnormal actin cortical patch morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cortical patches is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin patch morphology" EXACT [PomBase:mah] synonym: "abnormal F-actin patch morphology" EXACT [PomBase:mah] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology during vegetative growth relationship: output_of FYPO:0000790 ! abnormal actin cortical patch organization created_by: midori creation_date: 2012-02-29T03:14:15Z [Term] id: FYPO:0000792 name: normal glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-02-29T03:25:55Z [Term] id: FYPO:0000793 name: abnormal glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-02-29T03:26:33Z [Term] id: FYPO:0000794 name: abolished glycerol dehydrogenase activity def: "A molecular function phenotype in which glycerol dehydrogenase activity is absent." [PomBase:mah] synonym: "glycerol dehydrogenase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000793 ! abnormal glycerol dehydrogenase activity created_by: midori creation_date: 2012-02-29T03:27:45Z [Term] id: FYPO:0000795 name: decreased glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is decreased." [PomBase:mah] synonym: "reduced glycerol dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000793 ! abnormal glycerol dehydrogenase activity created_by: midori creation_date: 2012-02-29T03:27:51Z [Term] id: FYPO:0000796 name: increased glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000793 ! abnormal glycerol dehydrogenase activity created_by: midori creation_date: 2012-02-29T03:27:58Z [Term] id: FYPO:0000797 name: sensitive to tert-butyl hydroperoxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tert-butyl hydroperoxide (TBHP or t-BOOH). Cells stop growing (and may die) at a concentration of tert-butyl hydroperoxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tert-butyl hydroperoxide" EXACT [PomBase:mah] synonym: "sensitive to 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:64090] synonym: "sensitive to t-BOOH" EXACT [PomBase:al, PomBase:mah] synonym: "sensitive to TBHP" EXACT [CHEBI:64090, PomBase:al] synonym: "sensitive to tert-butyl hydroperoxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tert-butyl hydroperoxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-02-29T03:49:47Z [Term] id: FYPO:0000798 name: sensitive to anisomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to anisomycin. Cells stop growing (and may die) at a concentration of anisomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to anisomycin" EXACT [PomBase:mah] synonym: "sensitive to anisomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to anisomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-02-29T03:54:43Z [Term] id: FYPO:0000799 name: sensitive to diamide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide, also known as diamide. Cells stop growing (and may die) at a concentration of diamide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to diamide" EXACT [PomBase:mah] synonym: "sensitive to diamide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to diamide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-03-01T01:37:57Z [Term] id: FYPO:0000800 name: increased concentration of substance in growth medium def: "A phenotype in which the concentration of a substance released into the growth medium by cells is higher than normal." [PomBase:mah] comment: Note that this term refers only to substances released into the growth medium by cells, not to the concentration of ingredients in the medium as formulated. Consider also annotating to 'increased level of substance in cell' (FYPO:0000990), if there is evidence that the intracellular level of a substance is also increased. synonym: "increased accumulation of substance in growth medium" RELATED [PomBase:mah] synonym: "increased level of substance in growth medium" EXACT [PomBase:mah] synonym: "increased release of substance into growth medium" RELATED [PomBase:mah] is_a: FYPO:0001155 ! altered effect on growth medium created_by: midori creation_date: 2012-03-07T03:41:12Z [Term] id: FYPO:0000801 name: abnormal actin cytoskeleton organization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal." [GO:0030036, PMID:19713940, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton' (FYPO:0002398), but note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cytoskeleton organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001328 ! abnormal cytoskeleton organization during vegetative growth is_a: FYPO:0004803 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2012-03-01T02:05:28Z [Term] id: FYPO:0000802 name: abnormal cytoskeleton organization def: "A cellular process phenotype in which cytoskeleton organization is abnormal." [GO:0007010, PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in a physically abnormal cytoskeleton. synonym: "abnormal cytoskeleton organisation" EXACT [PomBase:mah] is_a: FYPO:0000295 ! cytoskeleton organization phenotype is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2012-03-01T02:43:53Z [Term] id: FYPO:0000803 name: increased concentration of DHA in growth medium def: "A phenotype in which the concentration of glycerone (also called 1,3-dihydroxypropan-2-one, dihydroxyacetone, or DHA) released into the growth medium by cells is higher than normal." [PomBase:mah] synonym: "increased accumulation of DHA in growth medium" RELATED [PomBase:mah] synonym: "increased concentration of 1,3-dihydroxypropan-2-one in growth medium" EXACT [CHEBI:16016] synonym: "increased concentration of dihydroxyacetone in growth medium" EXACT [CHEBI:16016] synonym: "increased concentration of glycerone in growth medium" EXACT [CHEBI:16016] synonym: "increased level of DHA in growth medium" EXACT [PomBase:mah] synonym: "increased release of DHA into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2012-03-07T03:42:46Z [Term] id: FYPO:0000804 name: abnormal endomembrane system organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endomembrane system organization is abnormal. Endomembrane system organization results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system, which encompasses the endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope." [GO:0010256, GO:0012505, PomBase:mah] comment: Consider annotating to 'abnormal endomembrane system morphology' (FYPO:0000353), but note that an abnormal endomembrane system organization process may, but does not necessarily, result in abnormal endomembrane system morphology. synonym: "abnormal endomembrane system organisation" EXACT [PomBase:mah] synonym: "abnormal endomembrane system organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal endomembrane system organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:25:09Z [Term] id: FYPO:0000805 name: abnormal endoplasmic reticulum organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endoplasmic reticulum (ER) organization is abnormal. ER organization results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum." [GO:0007029, PomBase:mah] comment: Consider annotating to 'abnormal endoplasmic reticulum morphology' (FYPO:0000354), but note that an abnormal endoplasmic reticulum organization process may, but does not necessarily, result in abnormal endoplasmic reticulum morphology. synonym: "abnormal endoplasmic reticulum organisation" EXACT [PomBase:mah] synonym: "abnormal endoplasmic reticulum organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal endoplasmic reticulum organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ER organization" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:25:48Z [Term] id: FYPO:0000806 name: abnormal Golgi organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Golgi organization is abnormal. Golgi organization results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GO:0007030, PomBase:mah] comment: Consider annotating to 'abnormal Golgi morphology' (FYPO:0000349), but note that an abnormal Golgi organization process may, but does not necessarily, result in abnormal Golgi morphology. synonym: "abnormal Golgi organisation" EXACT [PomBase:mah] synonym: "abnormal Golgi organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal Golgi organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:29:07Z [Term] id: FYPO:0000807 name: abnormal kinetochore organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore organization is abnormal. Kinetochore organization results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, the chromosomal attachment point for the spindle microtubules." [GO:0051383, PomBase:mah] comment: Consider annotating to 'abnormal kinetochore structure' (FYPO:0000050), but note that an abnormal kinetochore organization process may, but does not necessarily, result in abnormal kinetochore structure. synonym: "abnormal kinetochore organisation" EXACT [PomBase:mah] synonym: "abnormal kinetochore organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal kinetochore organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:29:58Z [Term] id: FYPO:0000808 name: abnormal lipid droplet organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lipid droplet organization is abnormal. Lipid droplet organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid droplet." [GO:0034389, PomBase:mah] comment: Consider annotating to 'abnormal lipid droplet morphology' (FYPO:0000356), but note that an abnormal lipid droplet organization process may, but does not necessarily, result in abnormal lipid droplet morphology. synonym: "abnormal lipid droplet organisation" EXACT [PomBase:mah] synonym: "abnormal lipid droplet organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal lipid droplet organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal lipid particle organization" EXACT [GO:0005811] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:31:02Z [Term] id: FYPO:0000809 name: abnormal mitochondrion organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion organization is abnormal. Mitochondrion organization results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion, and includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome, as well as synthesis of new mitochondrial components." [GO:0007005, PomBase:mah] comment: Consider annotating to 'abnormal mitochondrial morphology' (FYPO:0000359), but note that an abnormal mitochondrion organization process may, but does not necessarily, result in abnormal mitochondrial morphology. synonym: "abnormal mitochondrion organisation" EXACT [PomBase:mah] synonym: "abnormal mitochondrion organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrion organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:31:48Z [Term] id: FYPO:0000810 name: abnormal nucleus organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleus organization is abnormal. Nucleus organization results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GO:0006997, PomBase:mah] comment: Consider annotating to 'abnormal nuclear morphology' (FYPO:0000062), but note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "abnormal nuclear organization" EXACT [PomBase:mah] synonym: "abnormal nucleus organisation" EXACT [PomBase:mah] synonym: "abnormal nucleus organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleus organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:34:22Z [Term] id: FYPO:0000811 name: abnormal peroxisome organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome organization is abnormal. Peroxisome organization results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome." [GO:0007031, PomBase:mah] comment: Consider annotating to 'abnormal peroxisomal morphology' (FYPO:0000362), but note that an abnormal peroxisome organization process may, but does not necessarily, result in abnormal peroxisome morphology. synonym: "abnormal peroxisome organisation" EXACT [PomBase:mah] synonym: "abnormal peroxisome organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal peroxisome organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:38:04Z [Term] id: FYPO:0000812 name: abnormal vacuole organization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole organization is abnormal. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GO:0007033, PomBase:mah] comment: Consider annotating to 'abnormal vacuolar morphology during vegetative growth' (FYPO:0000368), but note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuolar organisation during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal vacuolar organization during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal vacuole organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vacuole organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0002803 ! abnormal vacuole organization created_by: midori creation_date: 2012-03-01T03:38:52Z [Term] id: FYPO:0000813 name: abnormal plasma membrane organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which plasma membrane organization is abnormal. Plasma membrane organization results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GO:0007009, PomBase:mah] comment: Consider annotating to 'abnormal plasma membrane morphology' (FYPO:0000364), but note that an abnormal plasma membrane organization process may, but does not necessarily, result in abnormal plasma membrane morphology. synonym: "abnormal plasma membrane organisation" EXACT [PomBase:mah] synonym: "abnormal plasma membrane organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal plasma membrane organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:41:39Z [Term] id: FYPO:0000814 name: abnormal nucleolus organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolus organization is abnormal. Nucleolus organization results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [PomBase:mah] comment: Consider annotating to 'abnormal nucleolar morphology' (FYPO:0000361), but note that an abnormal nucleolus organization process may, but does not necessarily, result in abnormal nucleolar morphology. synonym: "abnormal nucleolus organisation" EXACT [PomBase:mah] synonym: "abnormal nucleolus organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleolus organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000810 ! abnormal nucleus organization created_by: midori creation_date: 2012-03-01T03:42:44Z [Term] id: FYPO:0000815 name: abnormal nuclear envelope organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope organization is abnormal. Nuclear envelope organization results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [PomBase:mah] comment: Consider annotating to 'abnormal nuclear envelope morphology' (FYPO:0000769), but note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "abnormal nuclear envelope organisation" EXACT [PomBase:mah] synonym: "abnormal nuclear envelope organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear envelope organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000810 ! abnormal nucleus organization created_by: midori creation_date: 2012-03-01T03:45:03Z [Term] id: FYPO:0000816 name: decreased concentration of substance in growth medium def: "A phenotype in which the concentration of a substance released into the growth medium by cells is lower than normal." [PomBase:mah] comment: Note that this term refers only to substances released into the growth medium by cells, not to the concentration of ingredients in the medium as formulated. Consider also annotating to 'decreased level of substance in cell' (FYPO:0000991), if there is evidence that the intracellular level of a substance is also increased. synonym: "decreased accumulation of substance in growth medium" RELATED [PomBase:mah] synonym: "decreased level of substance in growth medium" EXACT [PomBase:mah] synonym: "decreased release of substance into growth medium" RELATED [PomBase:mah] synonym: "reduced concentration of substance in growth medium" EXACT [PomBase:mah] is_a: FYPO:0001155 ! altered effect on growth medium created_by: midori creation_date: 2012-03-07T03:47:46Z [Term] id: FYPO:0000817 name: increased concentration of pheromone in growth medium def: "A phenotype in which the concentration of a peptide pheromone released into the growth medium by cells is higher than normal." [PomBase:mah] synonym: "increased accumulation of pheromone in growth medium" RELATED [PomBase:mah] synonym: "increased concentration of peptide pheromone in growth medium" EXACT [PomBase:mah] synonym: "increased level of pheromone in growth medium" EXACT [PomBase:mah] synonym: "increased release of pheromone into growth medium" RELATED [PomBase:mah] synonym: "pheromone production: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2012-03-07T03:50:03Z [Term] id: FYPO:0000818 name: increased concentration of M-factor in growth medium def: "A phenotype in which the concentration of M-factor, the mating pheromone produced by mating type minus cells, released into the growth medium is higher than normal." [PomBase:mah] synonym: "increased accumulation of M-factor in growth medium" RELATED [PomBase:mah] synonym: "increased level of M-factor in growth medium" EXACT [PomBase:mah] synonym: "increased release of M-factor into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000817 ! increased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:12:02Z [Term] id: FYPO:0000819 name: increased concentration of P-factor in growth medium def: "A phenotype in which the concentration of P-factor, the mating pheromone produced by mating type plus cells, released into the growth medium is higher than normal." [PomBase:mah] synonym: "increased accumulation of P-factor in growth medium" RELATED [PomBase:mah] synonym: "increased level of P-factor in growth medium" EXACT [PomBase:mah] synonym: "increased release of P-factor into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000817 ! increased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:14:04Z [Term] id: FYPO:0000820 name: decreased concentration of pheromone in growth medium def: "A phenotype in which the concentration of a peptide pheromone released into the growth medium by cells is lower than normal." [PomBase:mah] synonym: "decreased accumulation of pheromone in growth medium" RELATED [PomBase:mah] synonym: "decreased concentration of peptide pheromone in growth medium" EXACT [PomBase:mah] synonym: "decreased level of pheromone in growth medium" EXACT [PomBase:mah] synonym: "decreased release of pheromone into growth medium" RELATED [PomBase:mah] synonym: "pheromone production: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced concentration of pheromone in growth medium" EXACT [PomBase:mah] is_a: FYPO:0000816 ! decreased concentration of substance in growth medium created_by: midori creation_date: 2012-03-07T04:14:58Z [Term] id: FYPO:0000821 name: decreased concentration of M-factor in growth medium def: "A phenotype in which the concentration of M-factor, the mating pheromone produced by mating type minus cells, released into the growth medium is lower than normal." [PomBase:mah] synonym: "decreased accumulation of M-factor in growth medium" RELATED [PomBase:mah] synonym: "decreased level of M-factor in growth medium" EXACT [PomBase:mah] synonym: "decreased release of M-factor into growth medium" RELATED [PomBase:mah] synonym: "reduced concentration of M-factor in growth medium" EXACT [PomBase:mah] is_a: FYPO:0000820 ! decreased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:15:08Z [Term] id: FYPO:0000822 name: decreased concentration of P-factor in growth medium def: "A phenotype in which the concentration of P-factor, the mating pheromone produced by mating type plus cells, released into the growth medium is lower than normal." [PomBase:mah] synonym: "decreased accumulation of P-factor in growth medium" RELATED [PomBase:mah] synonym: "decreased level of P-factor in growth medium" EXACT [PomBase:mah] synonym: "decreased release of P-factor into growth medium" RELATED [PomBase:mah] synonym: "reduced concentration of P-factor in growth medium" EXACT [PomBase:mah] is_a: FYPO:0000820 ! decreased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:15:24Z [Term] id: FYPO:0000824 name: altered RNA level def: "A cell phenotype in which the amount of RNA measured in a cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal RNA level" EXACT [PomBase:mah] synonym: "altered cellular mRNA level" NARROW [PomBase:vw] synonym: "altered cellular RNA level" EXACT [PomBase:mah] synonym: "altered transcript level" EXACT [PomBase:mah] synonym: "RNA accumulation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000989 ! altered level of substance in cell relationship: output_of FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2012-03-08T03:02:56Z [Term] id: FYPO:0000825 name: increased RNA level during vegetative growth alt_id: FYPO:0000910 alt_id: FYPO:0001247 alt_id: FYPO:0002936 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term or its descendants. synonym: "increased cellular mRNA level during vegetative growth" NARROW [PomBase:vw] synonym: "increased cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased messenger RNA level during vegetative growth" NARROW [PomBase:mah] synonym: "increased mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "increased mRNA transcript level during vegetative growth" NARROW [PomBase:vw] synonym: "increased RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "RNA accumulation: increased during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001326 ! altered RNA level during vegetative growth is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2012-03-08T03:15:26Z [Term] id: FYPO:0000826 name: decreased RNA level def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased cellular mRNA level" NARROW [PomBase:vw] synonym: "decreased cellular RNA level" EXACT [PomBase:mah] synonym: "decreased RNA accumulation" RELATED [PomBase:mah] synonym: "decreased transcript level" EXACT [PomBase:vw] synonym: "reduced RNA level" EXACT [PomBase:mah] synonym: "RNA accumulation: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000824 ! altered RNA level is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2012-03-08T03:16:30Z [Term] id: FYPO:0000827 name: premature cell cycle phase transition def: "A cellular process phenotype in which one or more cell cycle phase transitions begins earlier than normal." [PomBase:mah] synonym: "advanced cell cycle phase transition" EXACT [PomBase:mah] synonym: "premature cell cycle phase transition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature cell cycle phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "premature cell cycle progression" EXACT [PomBase:mah] synonym: "premature cell cycle progression during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-03-08T03:30:50Z [Term] id: FYPO:0000828 name: premature mitotic G1 phase entry def: "A cellular process phenotype in which entry into the G1 phase of the mitotic cell cycle (exit from mitosis) begins earlier than normal." [PomBase:mah] synonym: "accelerated entry into G1" RELATED [PomBase:al] synonym: "advanced mitotic G1 phase entry" EXACT [PomBase:mah] synonym: "advanced mitotic G1 progression" RELATED [PomBase:mah] synonym: "mitotic cell cycle advance in G1" RELATED [PomBase:mah] synonym: "premature exit from mitosis" EXACT [PomBase:mah] synonym: "premature G1 phase entry during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G1 phase entry during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000602 ! abnormal mitotic G1 phase progression is_a: FYPO:0000827 ! premature cell cycle phase transition created_by: midori creation_date: 2012-03-08T03:30:59Z [Term] id: FYPO:0000829 name: resistance to cisplatin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cisplatin than normal." [PomBase:mah] synonym: "resistance to cis-DPP" EXACT [CHEBI:27899] synonym: "resistance to cisplatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cisplatin during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to DPP" BROAD [CHEBI:27899] synonym: "resistant to cisplatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-03-08T03:43:33Z [Term] id: FYPO:0000830 name: resistance to vanadate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of vanadate ions (VO4(3-)) than normal." [PomBase:mah] comment: Vanadate is usually used in the form of trisodium vanadate (also known as sodium orthovanadate). synonym: "normal growth on sodium orthovanadate" EXACT [] synonym: "resistance to orthovanadate" EXACT [CHEBI:46442] synonym: "resistance to sodium orthovanadate" EXACT [] synonym: "resistance to vanadate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to vanadate during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to vanadate ions" EXACT [PomBase:mah] synonym: "resistance to vanadate(3-)" EXACT [CHEBI:46442] synonym: "resistance to vanadium oxoanion" BROAD [CHEBI:30528] synonym: "resistant to vanadate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-03-08T03:44:55Z [Term] id: FYPO:0000831 name: resistance to actinomycin D def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of actinomycin D than normal." [PomBase:mah] synonym: "resistance to actinomycin D during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to actinomycin D during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to actinomycin D" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-03-08T03:46:56Z [Term] id: FYPO:0000832 name: elongated nucleus during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is longer than normal." [PomBase:mah] synonym: "elongated nuclei during vegetative growth" EXACT [PomBase:vw] synonym: "elongated nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long nucleus during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth is_a: FYPO:0006663 ! elongated nucleus created_by: midori creation_date: 2012-03-09T03:40:40Z [Term] id: FYPO:0000833 name: normal protein level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth is_a: FYPO:0004083 ! normal protein level created_by: midori creation_date: 2012-03-09T03:50:03Z [Term] id: FYPO:0000834 name: altered protein level def: "A cell phenotype in which the amount of protein measured in a cell differs from normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. subset: qc_do_not_manually_annotate synonym: "abnormal protein level" EXACT [PomBase:mah] synonym: "altered cellular protein level" EXACT [PomBase:mah] synonym: "protein/peptide accumulation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000989 ! altered level of substance in cell relationship: output_of FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2012-03-09T03:50:50Z [Term] id: FYPO:0000835 name: decreased protein level def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation" RELATED [PomBase:mah] synonym: "protein/peptide accumulation: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced protein level" EXACT [PomBase:mah] is_a: FYPO:0000834 ! altered protein level is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2012-03-09T03:50:57Z [Term] id: FYPO:0000836 name: increased protein level def: "A cell phenotype in which the amount of protein measured in a cell is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation" RELATED [PomBase:mah] synonym: "protein/peptide accumulation: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000834 ! altered protein level is_a: FYPO:0000990 ! increased level of substance in cell created_by: midori creation_date: 2012-03-09T03:51:05Z [Term] id: FYPO:0000837 name: cell cycle arrest in mitotic interphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in any part of interphase. Includes normal and abnormal occurrences of arrest." [PomBase:mah] synonym: "cell cycle arrest in interphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle arrest in mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "interphase block" RELATED [PomBase:vw] synonym: "mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "mitotic interphase cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0004040 ! mitotic cell cycle arrest phenotype created_by: midori creation_date: 2012-03-09T04:18:58Z [Term] id: FYPO:0000838 name: normal protein localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0006553 ! normal protein localization to nucleus created_by: midori creation_date: 2012-03-12T03:24:23Z [Term] id: FYPO:0000839 name: inviable elongated mononucleate aseptate cell alt_id: FYPO:0004923 def: "A cell phenotype in which a cell contains one nucleus, has no septum, is elongated, and is inviable. Progression through the mitotic cell cycle is arrested in all inviable elongated mononucleate aseptate cells." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cell cycle-arrested elongated inviable mononucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest" EXACT [PomBase:mah] synonym: "elongated mononucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with arrested cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest" EXACT [PomBase:mah] synonym: "lethal; elongated mononucleate aseptate cell" EXACT [PomBase:mah] synonym: "long aseptate mononucleate cell" EXACT [PomBase:vw] synonym: "mitotic cell cycle arrest with elongated inviable mononucleate aseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression is_a: FYPO:0002066 ! inviable elongated aseptate cell is_a: FYPO:0003763 ! inviable aseptate mononucleate vegetative cell is_a: FYPO:0004255 ! inviable elongated mononucleate vegetative cell is_a: FYPO:0005773 ! elongated mononucleate aseptate vegetative cell relationship: has_part FYPO:0000502 ! abnormally arrested mitotic cell cycle progression created_by: midori creation_date: 2012-03-12T03:25:38Z [Term] id: FYPO:0000840 name: normal RNA level def: "A cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] synonym: "normal cellular RNA level" EXACT [PomBase:mah] synonym: "normal mRNA level" NARROW [PomBase:mah] synonym: "normal transcript level" EXACT [PomBase:mah] synonym: "RNA accumulation: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2012-03-14T12:06:03Z [Term] id: FYPO:0000841 name: sensitive to sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium dodecyl sulfate (SDS). Cells stop growing (and may die) at a concentration of SDS that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium dodecyl sulfate" EXACT [PomBase:mah] synonym: "sensitive to SDS" EXACT [CHEBI:8984] synonym: "sensitive to sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to sodium dodecyl sulphate" EXACT [CHEBI:8984] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-03-14T01:14:35Z [Term] id: FYPO:0000842 name: sensitive to ethanol during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethanol. Cells stop growing (and may die) at a concentration of ethanol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to ethanol during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ethanol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ethyl alcohol during vegetative growth" EXACT [CHEBI:16236] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-03-14T01:25:07Z [Term] id: FYPO:0000843 name: sensitive to dithiothreitol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,4-dithiothreitol (DTT). Cells stop growing (and may die) at a concentration of dithiothreitol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to dithiothreitol" EXACT [PomBase:mah] synonym: "sensitive to 1,4-dithiothreitol" EXACT [CHEBI:18320] synonym: "sensitive to dithiothreitol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to dithiothreitol during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DTT" EXACT [PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-03-14T01:26:35Z [Term] id: FYPO:0000844 name: sensitive to mercaptoethanol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercaptoethanol. Cells stop growing (and may die) at a concentration of mercaptoethanol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mercaptoethanol" EXACT [PomBase:mah] synonym: "sensitive to 2-sulfanylethanol" EXACT [CHEBI:41218] synonym: "sensitive to mercaptoethanol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to mercaptoethanol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-03-14T01:27:55Z [Term] id: FYPO:0000845 name: abnormal protein degradation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is abnormal. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein breakdown during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolism during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein degradation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000328 ! abnormal protein metabolic process during vegetative growth is_a: FYPO:0002275 ! abnormal protein degradation created_by: midori creation_date: 2012-03-14T02:33:44Z [Term] id: FYPO:0000846 name: decreased protein degradation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein degradation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth is_a: FYPO:0002797 ! decreased protein degradation relationship: has_output FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-03-14T02:57:05Z [Term] id: FYPO:0000847 name: increased protein degradation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein breakdown during vegetative growth" EXACT [GO:0030163] synonym: "increased protein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolism during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein degradation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth is_a: FYPO:0002276 ! increased protein degradation relationship: has_output FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2012-03-14T03:00:52Z [Term] id: FYPO:0000848 name: abnormal chromosome morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of one or more chromosomes is abnormal." [PomBase:mah] comment: Note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. synonym: "abnormal chromosome morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0005600 ! abnormal chromosome morphology relationship: output_of FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2012-03-14T03:09:26Z [Term] id: FYPO:0000849 name: increased cytoplasmic protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in the cytoplasm of a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "cytoplasmic accumulation of protein" EXACT [PomBase:mah] synonym: "cytoplasmic protein accumulation during vegetative growth" EXACT [PomBase:mah] synonym: "increased cytoplasmic protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level in cytoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-03-14T04:24:49Z [Term] id: FYPO:0000850 name: resistance to stress during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a stress. Typically, a cell population is deemed resistant to a stress if cells in the population grow and divide when exposed to the stress at an intensity at which wild-type cells stop growing (and may die)." [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to stress" EXACT [PomBase:mah] synonym: "resistance to stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistant to stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001358 ! vegetative cell population growth phenotype is_a: FYPO:0002046 ! resistance to stress created_by: midori creation_date: 2012-03-15T10:55:12Z [Term] id: FYPO:0000851 name: resistance to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to osmotic stress." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to osmotic stress in culture. If you have assayed the response to osmotic stress at the subcellular or molecular level, consider annotating to 'abnormal cellular response to osmotic stress' (FYPO:0000193). synonym: "increased growth during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "resistance to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2012-03-15T10:55:59Z [Term] id: FYPO:0000852 name: resistance to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a salt stress." [PomBase:mah] synonym: "increased growth during cellular response to salt stress" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to salt stress" EXACT [PomBase:mah] synonym: "ionic stress resistance: increased" RELATED [SGD:phenotype_annotation] synonym: "resistance to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistant to salt stress" EXACT [PomBase:mah] synonym: "resistant to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000851 ! resistance to osmotic stress created_by: midori creation_date: 2012-03-15T10:56:15Z [Term] id: FYPO:0000853 name: abnormal nucleosome positioning def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome occupancy" RELATED [PomBase:mah, PomBase:vw] synonym: "abnormal nucleosome positioning during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleosome positioning during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2012-03-20T11:46:43Z [Term] id: FYPO:0000854 name: abnormal nucleosome positioning in euchromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome occupancy in euchromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "abnormal nucleosome positioning in euchromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleosome positioning in euchromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing in euchromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000853 ! abnormal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:52:16Z [Term] id: FYPO:0000855 name: abnormal nucleosome positioning in heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of heterochromatin is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome occupancy in heterochromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "abnormal nucleosome positioning in heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleosome positioning in heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing in heterochromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000853 ! abnormal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:53:31Z [Term] id: FYPO:0000856 name: normal nucleosome positioning def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome occupancy" RELATED [PomBase:mah, PomBase:vw] synonym: "normal nucleosome positioning during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleosome positioning during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-20T11:54:42Z [Term] id: FYPO:0000857 name: normal nucleosome positioning in euchromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome occupancy in euchromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "normal nucleosome positioning in euchromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleosome positioning in euchromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing in euchromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000856 ! normal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:55:39Z [Term] id: FYPO:0000858 name: normal nucleosome positioning in heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of heterochromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome occupancy in heterochromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "normal nucleosome positioning in heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleosome positioning in heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing in heterochromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000856 ! normal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:55:49Z [Term] id: FYPO:0000859 name: normal metabolic process during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cellular metabolic process is normal (i.e. indistinguishable from wild type). A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] synonym: "normal cellular metabolic process during vegetative growth" EXACT [GO:0044237, PomBase:mah] synonym: "normal metabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal metabolism during vegetative growth" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth is_a: FYPO:0002496 ! normal metabolic process created_by: midori creation_date: 2012-03-20T12:10:04Z [Term] id: FYPO:0000860 name: abnormal metabolic process def: "A cellular process phenotype in which a cellular metabolic process is abnormal. A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular metabolic process" EXACT [GO:0044237, PomBase:mah] synonym: "abnormal metabolism" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2012-03-20T12:11:59Z [Term] id: FYPO:0000861 name: normal histone methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone methylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002600 ! normal histone modification during vegetative growth created_by: midori creation_date: 2012-03-20T12:15:03Z [Term] id: FYPO:0000862 name: normal histone H3-K9 dimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal centromeric histone H3-K9 dimethylation" EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me2 at centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T12:18:40Z [Term] id: FYPO:0000863 name: normal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "normal histone H3-K9 dimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K9me2 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000862 ! normal histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T12:20:16Z [Term] id: FYPO:0000864 name: abnormal histone H3-K9 trimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions is abnormal." [PomBase:mah] synonym: "abnormal centromeric histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation at centromere during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me3 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 trimethylation at centromere during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:22:17Z [Term] id: FYPO:0000865 name: abnormal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "abnormal histone H3-K9 trimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me3 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T12:25:24Z [Term] id: FYPO:0000866 name: abnormal histone H3-K9 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me2 during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:28:22Z [Term] id: FYPO:0000867 name: abnormal histone H3-K9 dimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions is abnormal." [PomBase:mah] synonym: "abnormal centromeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me2 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000866 ! abnormal histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:29:39Z [Term] id: FYPO:0000868 name: abnormal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere imr during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3-K9 dimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me2 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T12:29:52Z [Term] id: FYPO:0000869 name: increased histone methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation occurs to a greater extent than normal. All histone methylation may be affected, or methylation of specific sites on specific histones may be increased." [PomBase:mah] synonym: "increased histone methylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:32:05Z [Term] id: FYPO:0000870 name: decreased histone methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation occurs to a lower extent than normal. All histone methylation may be affected, or methylation of specific sites on specific histones may be decreased." [PomBase:mah] synonym: "decreased histone methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:32:18Z [Term] id: FYPO:0000871 name: increased histone H3-K9 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9me during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation during vegetative growth is_a: FYPO:0000869 ! increased histone methylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:33:11Z [Term] id: FYPO:0000872 name: decreased histone H3-K9 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9me during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation during vegetative growth is_a: FYPO:0000870 ! decreased histone methylation during vegetative growth created_by: midori creation_date: 2012-03-20T12:34:25Z [Term] id: FYPO:0000873 name: increased histone H3-K9 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000866 ! abnormal histone H3-K9 dimethylation during vegetative growth is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:25:01Z [Term] id: FYPO:0000874 name: increased histone H3-K9 dimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere during vegetative growth is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:25:10Z [Term] id: FYPO:0000875 name: increased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "increased histone H3-K9 dimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000868 ! abnormal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth is_a: FYPO:0000874 ! increased histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T01:25:53Z [Term] id: FYPO:0000876 name: decreased histone H3-K9 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000866 ! abnormal histone H3-K9 dimethylation during vegetative growth is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:35:21Z [Term] id: FYPO:0000877 name: decreased histone H3-K9 dimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased centromeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere during vegetative growth is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:36:04Z [Term] id: FYPO:0000878 name: decreased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "decreased histone H3-K9 dimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "v histone lysine H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000868 ! abnormal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth is_a: FYPO:0000877 ! decreased histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T01:36:23Z [Term] id: FYPO:0000879 name: increased histone H3-K9 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me3 during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation during vegetative growth is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:42:40Z [Term] id: FYPO:0000880 name: increased histone H3-K9 trimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3 K9 trimethylation at centromere during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me3 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation at centromere during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere during vegetative growth is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation during vegetative growth is_a: FYPO:0007374 ! abnormal histone methylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T01:42:53Z [Term] id: FYPO:0000881 name: increased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "increased histone H3-K9 trimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me3 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000865 ! abnormal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth is_a: FYPO:0000880 ! increased histone H3-K9 trimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T01:43:01Z [Term] id: FYPO:0000882 name: decreased histone H3-K9 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 trimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me3 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation during vegetative growth is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:31Z [Term] id: FYPO:0000883 name: decreased histone H3-K9 trimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased centromeric histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at centromere during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me3 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 trimethylation at centromere during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere during vegetative growth is_a: FYPO:0000882 ! decreased histone H3-K9 trimethylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:38Z [Term] id: FYPO:0000884 name: decreased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "decreased histone H3-K9 trimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me3 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000865 ! abnormal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth is_a: FYPO:0000883 ! decreased histone H3-K9 trimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000885 name: abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me3 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T12:25:24Z [Term] id: FYPO:0000886 name: abnormal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal histone H3K9me2 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2012-03-20T12:29:52Z [Term] id: FYPO:0000887 name: increased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000874 ! increased histone H3-K9 dimethylation at centromere during vegetative growth is_a: FYPO:0000886 ! abnormal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth created_by: midori creation_date: 2012-03-20T01:25:53Z [Term] id: FYPO:0000888 name: decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000877 ! decreased histone H3-K9 dimethylation at centromere during vegetative growth is_a: FYPO:0000886 ! abnormal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth created_by: midori creation_date: 2012-03-20T01:36:23Z [Term] id: FYPO:0000889 name: increased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 trimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K9 trimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me3 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000880 ! increased histone H3-K9 trimethylation at centromere during vegetative growth is_a: FYPO:0000885 ! abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth created_by: midori creation_date: 2012-03-20T01:43:01Z [Term] id: FYPO:0000890 name: decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me3 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000883 ! decreased histone H3-K9 trimethylation at centromere during vegetative growth is_a: FYPO:0000885 ! abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000891 name: abnormal histone H3-K9 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3-K9 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:vw] is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000892 name: increased histone H3-K9 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K9 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:vw] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000893 name: increased histone H3-K9 acetylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "increased histone H3-K9 acetylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 acetylation at centromere during vegetative growth" EXACT [GO:0043970, PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000894 name: abnormal intracellular mitochondrion distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which intracellular mitochondrion distribution, the process that results in the spatial arrangement of mitochondria in a cell, is abnormal." [GO:0048312, PomBase:mah] synonym: "abnormal intracellular mitochondrion distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal intracellular mitochondrion distribution during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000489 ! abnormal mitochondrial distribution created_by: midori creation_date: 2012-03-29T02:42:20Z [Term] id: FYPO:0000895 name: mitochondrial aggregation alt_id: FYPO:0000896 def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal with a cluster distal to one or both sides of the nucleus." [PomBase:mah] synonym: "aggregated mitochondria" EXACT [PomBase:vw] synonym: "mitochondrial aggregation at cell end" RELATED [PomBase:mah] synonym: "mitochondrial aggregation at cell tip" RELATED [PomBase:mah] synonym: "mitochondrial aggregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial aggregation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology is_a: FYPO:0000894 ! abnormal intracellular mitochondrion distribution created_by: midori creation_date: 2012-03-29T02:45:02Z [Term] id: FYPO:0000897 name: normal mitochondrial fission def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, is normal (i.e. indistinguishable from wild type)." [GO:0000266, PomBase:mah] synonym: "normal mitochondrial division" EXACT [GO:0000266, PomBase:mah] synonym: "normal mitochondrial fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial fission during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitochondrial proliferation" RELATED [GO:0000266, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-29T02:55:09Z [Term] id: FYPO:0000898 name: normal mitochondrial fusion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fusion, the merging of two or more separate mitochondria into a single compartment, is normal (i.e. indistinguishable from wild type)." [GO:0008053, PomBase:mah] synonym: "normal mitochondrial fusion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial fusion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-29T02:56:39Z [Term] id: FYPO:0000899 name: normal microtubule cytoskeleton organization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule cytoskeleton organization is normal (i.e. indistinguishable from wild type). Microtubule cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] synonym: "normal microtubule cytoskeleton organisation during vegetative growth" EXACT [PomBase:mah] synonym: "normal microtubule cytoskeleton organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal microtubule dynamics during vegetative growth" EXACT [GO:0000226, PomBase:mah] synonym: "normal microtubule organization during vegetative growth" RELATED [GO:0000226, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-29T03:10:18Z [Term] id: FYPO:0000900 name: abnormal linear element assembly def: "A cellular process phenotype in which linear element assembly is abnormal. Linear element assembly includes the assembly of LinE complexes and their close association with chromatin to form a proteinaceous scaffold (related to the synaptonemal complex) on chromosomes during meiotic prophase." [PMID:30640914, PomBase:mah] synonym: "abnormal linear element formation" EXACT [GO:0030999, PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2012-03-30T04:40:50Z [Term] id: FYPO:0000901 name: abnormal microtubule dynamics during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule growth (polymerization), catastrophe (the transition from growth to shrinkage), shrinkage (depolymerization), or rescue (the transition from shrinkage to growth) is abnormal." [GO:0031109, PomBase:val] synonym: "abnormal microtubule growth or shrinkage during vegetative growth" NARROW [PomBase:vw] synonym: "abnormal microtubule polymerisation or depolymerisation during vegetative growth" NARROW [PomBase:val] synonym: "abnormal microtubule polymerization or depolymerization during vegetative growth" NARROW [PomBase:val] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-03-29T03:29:01Z [Term] id: FYPO:0000902 name: abnormal microtubule depolymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal." [GO:0007019, PomBase:mah] synonym: "abnormal microtubule catastrophe during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal microtubule depolymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal microtubule depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal microtubule shrinkage during vegetative growth" RELATED [PomBase:vw] is_a: FYPO:0000901 ! abnormal microtubule dynamics during vegetative growth is_a: FYPO:0007111 ! abnormal microtubule depolymerization created_by: midori creation_date: 2012-03-29T03:30:40Z [Term] id: FYPO:0000903 name: decreased rate of microtubule depolymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, occurs at a lower rate, or speed, than normal." [GO:0007019, PomBase:mah] synonym: "decreased microtubule depolymerization rate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of microtubule catastrophe during vegetative growth" RELATED [PomBase:mah] synonym: "decreased rate of microtubule depolymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of microtubule depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of microtubule shrinkage during vegetative growth" RELATED [PomBase:vw] synonym: "increased microtubule stability during vegetative growth" RELATED [PomBase:vw] synonym: "reduced rate of microtubule depolymerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007954 ! abnormal rate of microtubule depolymerization during vegetative growth created_by: midori creation_date: 2012-03-29T03:32:17Z [Term] id: FYPO:0000904 name: decreased microtubule polymerization or depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization or depolymerization, by the addition or removal of tubulin dimers respectively, occurs to a lesser extent than normal. Microtubules are thus less dynamic than normal." [GO:0031109, PomBase:mah] synonym: "decreased microtubule dynamicity" RELATED [PomBase:vw] synonym: "decreased microtubule growth or shrinkage" RELATED [PomBase:vw] synonym: "decreased microtubule polymerisation or depolymerisation" EXACT [PomBase:mah] synonym: "decreased microtubule polymerization or depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased microtubule polymerization or depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced microtubule polymerization or depolymerization" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-03-29T03:33:35Z [Term] id: FYPO:0000905 name: abnormal protein ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein ubiquitinylation during vegetative growth" RELATED [GO:0016567, PomBase:mah] synonym: "abnormal protein ubiquitylation during vegetative growth" EXACT [GO:0016567, PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0006977 ! abnormal protein ubiquitination created_by: midori creation_date: 2012-03-30T04:12:43Z [Term] id: FYPO:0000906 name: abnormal mitochondrion inheritance during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrial inheritance during vegetative growth" EXACT [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrion inheritance during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000489 ! abnormal mitochondrial distribution is_a: FYPO:0007274 ! abnormal mitochondrion inheritance created_by: midori creation_date: 2012-03-29T03:41:35Z [Term] id: FYPO:0000907 name: abolished mitochondrion inheritance during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abolished, resulting in the formation of a daughter cell that lacks mitochondria." [GO:0000001, PomBase:mah] synonym: "abolished mitochondrion inheritance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric mitochondrial inheritance during vegetative growth" RELATED [PomBase:vw] synonym: "mitochondrion inheritance abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000906 ! abnormal mitochondrion inheritance during vegetative growth created_by: midori creation_date: 2012-03-29T03:47:40Z [Term] id: FYPO:0000908 name: obsolete mixed population including viable and inviable cells def: "OBSOLETE. A mixed population phenotype in which some cells in a population are viable and others are inviable." [PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2012-03-29T03:52:40Z [Term] id: FYPO:0000909 name: abnormal protein localization to linear element def: "A cell phenotype in which the localization of a protein to linear elements is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at linear elements and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to linear element" EXACT [GO:0036181, PomBase:mah] is_a: FYPO:0002957 ! abnormal protein localization to nucleus during meiosis is_a: FYPO:0003549 ! abnormal protein localization during meiosis created_by: midori creation_date: 2012-03-30T04:48:31Z [Term] id: FYPO:0000911 name: increased nuclear RNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the cell nucleus is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:12896976, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased nuclear RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nuclear transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "increased RNA level in nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear accumulation of mRNA" NARROW [PomBase:mah] synonym: "nuclear accumulation of RNA" RELATED [PomBase:mah] synonym: "nuclear mRNA accumulation during vegetative growth" NARROW [PomBase:mah] synonym: "nuclear RNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002403 ! abnormal nucleus created_by: midori creation_date: 2012-03-29T04:01:15Z [Term] id: FYPO:0000912 name: abolished protein ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein ubiquitinylation during vegetative growth" RELATED [GO:0016567, PomBase:mah] synonym: "abolished protein ubiquitylation during vegetative growth" EXACT [GO:0016567, PomBase:mah] synonym: "protein ubiquitination abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0000905 ! abnormal protein ubiquitination during vegetative growth created_by: midori creation_date: 2012-03-30T04:14:39Z [Term] id: FYPO:0000913 name: abnormal sporulation resulting in formation of ascus containing non-uniform spores def: "A sporulation phenotype that results in the formation of an ascus that contains spores of non-uniform size and DNA content." [PMID:20298435, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation ascus containing non-uniform spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of asci containing non-uniform spores" RELATED [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2012-04-02T12:04:59Z [Term] id: FYPO:0000914 name: normal glutamate-ammonia ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-ammonia ligase (also known as glutamine synthetase) activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glutamine synthetase activity" EXACT [GO:0004356, PomBase:mah] synonym: "normal glutamylhydroxamic synthetase activity" EXACT [GO:0004356] synonym: "normal GS activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-04-02T01:46:50Z [Term] id: FYPO:0000915 name: abnormal pyruvate dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyruvate dehydrogenase activity is abnormal." [PomBase:mah] synonym: "abnormal PDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-02T01:51:18Z [Term] id: FYPO:0000916 name: decreased pyruvate dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyruvate dehydrogenase activity is decreased." [PomBase:mah] synonym: "decreased PDH activity" EXACT [PMID:7851743, PomBase:al] synonym: "reduced pyruvate dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000915 ! abnormal pyruvate dehydrogenase activity created_by: midori creation_date: 2012-04-02T01:51:30Z [Term] id: FYPO:0000917 name: abnormal citrate (Si)-synthase activity def: "A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is abnormal." [PomBase:mah] synonym: "abnormal citrate synthase activity" BROAD [GO:0004108, PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-02T01:54:26Z [Term] id: FYPO:0000918 name: decreased citrate (Si)-synthase activity def: "A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is decreased." [PomBase:mah] synonym: "decreased citrate synthase activity" BROAD [GO:0004108, PMID:7851743, PomBase:al] synonym: "reduced citrate (Si)-synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000917 ! abnormal citrate (Si)-synthase activity created_by: midori creation_date: 2012-04-02T01:54:32Z [Term] id: FYPO:0000919 name: increased citrate (Si)-synthase activity def: "A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is increased." [PomBase:mah] synonym: "increased citrate synthase activity" BROAD [GO:0004108, PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000917 ! abnormal citrate (Si)-synthase activity created_by: midori creation_date: 2012-04-02T02:24:33Z [Term] id: FYPO:0000920 name: abnormal aconitate hydratase activity def: "A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is abnormal." [PomBase:mah] synonym: "abnormal aconitase activity" EXACT [GO:0003994, PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-02T02:26:26Z [Term] id: FYPO:0000921 name: increased aconitate hydratase activity def: "A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is increased." [PomBase:mah] synonym: "increased aconitase activity" EXACT [GO:0003994, PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000920 ! abnormal aconitate hydratase activity created_by: midori creation_date: 2012-04-02T02:26:32Z [Term] id: FYPO:0000922 name: abnormal isocitrate dehydrogenase (NAD+) activity def: "A molecular function phenotype in which the observed rate of isocitrate dehydrogenase (NAD+) activity is abnormal." [PomBase:mah] synonym: "abnormal NAD-IDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-02T02:33:48Z [Term] id: FYPO:0000923 name: increased isocitrate dehydrogenase (NAD+) activity def: "A molecular function phenotype in which the observed rate of isocitrate dehydrogenase (NAD+) activity is increased." [PomBase:mah] synonym: "increased NAD-IDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000922 ! abnormal isocitrate dehydrogenase (NAD+) activity created_by: midori creation_date: 2012-04-02T02:33:56Z [Term] id: FYPO:0000924 name: resistance to anisomycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of anisomycin than normal." [PomBase:mah] synonym: "resistance to anisomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to anisomycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to anisomycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-04-02T02:43:27Z [Term] id: FYPO:0000925 name: unequal meiotic chromosome segregation def: "A cellular process phenotype in which chromosomes are not segregated equally to the two spindle poles in a meiotic nuclear division." [PomBase:mah] synonym: "abnormal meiotic chromosome disjunction" EXACT [PomBase:mah] synonym: "chromosome non-disjunction at meiosis" RELATED [PomBase:vw] synonym: "meiotic chromosome nondisjunction" RELATED [PomBase:mah] is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2012-04-02T03:09:45Z [Term] id: FYPO:0000926 name: normal volume vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal volume." [PomBase:mah] synonym: "normal volume cells during vegetative growth" EXACT [PomBase:mah] synonym: "normal volume vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001124 ! normal vegetative cell size is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2012-04-03T03:12:03Z [Term] id: FYPO:0000927 name: abolished horsetail movement def: "A cellular process phenotype in which horsetail movement does not occur. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] synonym: "absent horsetail movement" EXACT [PomBase:vw] synonym: "dynein-driven meiotic oscillatory nuclear movement abolished" EXACT [GO:0030989, PomBase:mah] synonym: "horsetail movement abolished" EXACT [PomBase:mah] synonym: "horsetail nuclear movement abolished" EXACT [GO:0030989, PomBase:mah] is_a: FYPO:0000197 ! abnormal horsetail movement created_by: midori creation_date: 2012-04-02T03:23:19Z [Term] id: FYPO:0000928 name: abnormal protein localization to cell cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell cortex during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0006867 ! abnormal protein localization to cell cortex created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000929 name: decreased protein localization to cell cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to cell cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000930 name: abolished protein localization to cell cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from cell cortex during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to cell cortex abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex during vegetative growth is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000931 name: abnormal protein localization to microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the microtubule cytoskeleton and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004090 ! abnormal protein localization to microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000932 name: increased protein localization to microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000933 name: decreased protein localization to microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000934 name: abolished protein localization to microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from microtubule cytoskeleton during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to microtubule cytoskeleton abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0004091 ! abolished protein localization to microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000935 name: abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the cortical microtubule cytoskeleton and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cortical microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004265 ! abnormal protein localization to cortical microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000936 name: increased protein localization to cortical microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to cortical microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000932 ! increased protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0000935 ! abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000937 name: decreased protein localization to cortical microtubule cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cortical microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000933 ! decreased protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0000935 ! abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000938 name: abolished protein localization to cortical microtubule cytoskeleton during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton during interphase of the mitotic cell cycle does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cortical microtubule cytoskeleton mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cortical microtubule cytoskeleton during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein absent from cortical microtubule cytoskeleton during mitotic interphase" RELATED [PomBase:mah] synonym: "protein localization to cortical microtubule cytoskeleton abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0000930 ! abolished protein localization to cell cortex during vegetative growth is_a: FYPO:0000934 ! abolished protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0000935 ! abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth is_a: FYPO:0004266 ! abolished protein localization to cortical microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000939 name: abnormal protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "abnormal protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000940 name: decreased protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body is_a: FYPO:0002770 ! decreased protein localization to spindle pole body created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000941 name: abolished protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from mitotic spindle pole body" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle pole body abolished" EXACT [PomBase:mah] synonym: "protein localization to mitotic SPB abolished" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle pole body abolished" EXACT [PomBase:mah] synonym: "protein localization to spindle pole body abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000942 name: abnormal nucleus positioning in prospore def: "A cellular process phenotype in which nucleus localization is abnormal in a prospore." [PomBase:mah] synonym: "abnormal nuclear localization in prospore" EXACT [PomBase:mah] synonym: "abnormal nucleus localisation in prospore" EXACT [PomBase:mah] synonym: "abnormal nucleus localization in ascospore-type prospore" EXACT [GO:0005628, PomBase:mah] synonym: "abnormal nucleus localization in forespore" EXACT [PomBase:mah] synonym: "abnormal nucleus localization in prospore" EXACT [] is_a: FYPO:0000517 ! abnormal nucleus positioning created_by: midori creation_date: 2012-04-02T04:22:13Z [Term] id: FYPO:0000943 name: normal spore morphology def: "A cell phenotype characterized by normal spore morphology, i.e. the size, shape, and structure of the spore are indistinguishable from wild type." [PomBase:mah] is_a: FYPO:0000672 ! normal cell morphology created_by: midori creation_date: 2012-04-03T02:27:00Z [Term] id: FYPO:0000944 name: inviable spore with normal morphology def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a normal morphology (i.e. size, shape, or structure). An inviable spore does not germinate." [PomBase:mah] synonym: "lethal; spore with normal morphology" EXACT [PomBase:mah] synonym: "spore germination abolished, normal spore morphology" RELATED [PomBase:mah] is_a: FYPO:0000943 ! normal spore morphology is_a: FYPO:0002151 ! inviable spore created_by: midori creation_date: 2012-04-03T02:28:22Z [Term] id: FYPO:0000945 name: swollen spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "enlarged spheroid vegetative cell" RELATED [PomBase:mah] synonym: "enlarged volume spheroid vegetative cell" EXACT [PomBase:mah] synonym: "large spheroid vegetative cell" RELATED [PomBase:vw] synonym: "spheroid vegetative cell with increased cell size" RELATED [PomBase:vw] synonym: "spheroid vegetative cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen rounded vegetative cell" EXACT [PomBase:mah] synonym: "swollen spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "swollen spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0002941 ! swollen spheroid cell relationship: has_part FYPO:0000021 ! spheroid vegetative cell relationship: has_part FYPO:0000646 ! swollen vegetative cell created_by: midori creation_date: 2012-04-03T03:14:05Z [Term] id: FYPO:0000946 name: normal volume spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, and has a normal volume." [PomBase:mah] synonym: "normal volume rounded vegetative cell" EXACT [PomBase:mah] synonym: "normal volume spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "normal volume spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0000926 ! normal volume vegetative cell is_a: FYPO:0001121 ! vegetative cell, abnormal cell shape, normal cell size relationship: has_part FYPO:0000021 ! spheroid vegetative cell relationship: has_part FYPO:0000926 ! normal volume vegetative cell created_by: midori creation_date: 2012-04-03T03:16:37Z [Term] id: FYPO:0000947 name: swollen spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a sphere, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "enlarged spherical vegetative cell" RELATED [PomBase:mah] synonym: "enlarged volume spherical vegetative cell" EXACT [PomBase:mah] synonym: "large spherical vegetative cell" RELATED [PomBase:vw] synonym: "spherical vegetative cell with increased cell size" RELATED [PomBase:vw] synonym: "spherical vegetative cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen orb during vegetative growth" EXACT [PomBase:vw] synonym: "swollen spherical cell during vegetative growth" EXACT [PomBase:mah] synonym: "swollen spherical vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000129 ! spherical vegetative cell is_a: FYPO:0000945 ! swollen spheroid vegetative cell relationship: has_part FYPO:0000129 ! spherical vegetative cell created_by: midori creation_date: 2012-04-03T03:27:05Z [Term] id: FYPO:0000948 name: normal volume spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a sphere, and has a normal volume." [PomBase:mah] synonym: "normal volume orb during vegetative growth" EXACT [PomBase:vw] synonym: "normal volume spherical cell during vegetative growth" EXACT [PomBase:mah] synonym: "normal volume spherical vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000129 ! spherical vegetative cell is_a: FYPO:0000946 ! normal volume spheroid vegetative cell relationship: has_part FYPO:0000129 ! spherical vegetative cell created_by: midori creation_date: 2012-04-03T03:28:08Z [Term] id: FYPO:0000949 name: aseptate def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell does not contain a septum." [PomBase:mah] synonym: "absent septum" EXACT [PomBase:mah] synonym: "aseptate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "aseptate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth relationship: output_of FYPO:0000272 ! abolished septum assembly created_by: midori creation_date: 2012-04-03T03:38:09Z [Term] id: FYPO:0000950 name: elongated aseptate vegetative cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell does not contain a septum and is elongated." [PomBase:mah] synonym: "elongated aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated aseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000949 ! aseptate is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000949 ! aseptate relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2012-04-03T03:41:12Z [Term] id: FYPO:0000951 name: inviable small vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable and has an abnormally low volume." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable small vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; small vegetative cell" EXACT [PomBase:mah] synonym: "small inviable cell during vegetative growth" EXACT [PomBase:mah] synonym: "small inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000645 ! small vegetative cell is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000645 ! small vegetative cell relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-04-03T04:12:31Z [Term] id: FYPO:0000952 name: vacuoles present in increased numbers during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more vacuoles than normal." [PomBase:mah] synonym: "additional vacuoles present during vegetative growth" EXACT [PomBase:mah] synonym: "extra vacuoles during vegetative growth" EXACT [PomBase:mah] synonym: "vacuoles present in greater numbers during vegetative growth" EXACT [PomBase:mah] synonym: "vacuoles present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002790 ! vacuoles present in increased numbers is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-04-03T04:18:23Z [Term] id: FYPO:0000953 name: normal cellular response to chemical stimulus def: "A cellular response phenotype in which the cellular response to a chemical stimulus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2012-04-12T12:15:57Z [Term] id: FYPO:0000954 name: normal growth on nickel cation def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nickel cations." [PomBase:mah] synonym: "normal cell population growth in presence of nickel cations" EXACT [PomBase:mah] synonym: "normal cell population growth on nickel" EXACT [GO:0071289, PomBase:mah] synonym: "normal cell population growth on nickel cation" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to nickel cation" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on nickel cation" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:18:01Z [Term] id: FYPO:0000955 name: normal growth on lead ion def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing lead ions." [PomBase:mah] synonym: "normal cell population growth in presence of lead ion" EXACT [PomBase:mah] synonym: "normal cell population growth on lead ion" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to lead ion" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on lead ion" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:21:54Z [Term] id: FYPO:0000956 name: normal growth on bismuth def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing bismuth ions." [PomBase:mah] synonym: "normal cell population growth in presence of bismuth" EXACT [PomBase:mah] synonym: "normal cell population growth on bismuth" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to bismuth" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on bismuth ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on bismuth" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:22:52Z [Term] id: FYPO:0000957 name: normal growth on methyl methanesulfonate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methyl methanesulfonate." [PomBase:mah] synonym: "normal cell population growth in presence of methyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal cell population growth on methyl methanesulfonate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on MMS" EXACT [CHEBI:25255] synonym: "normal cellular response to methyl methanesulfonate" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:23:26Z [Term] id: FYPO:0000958 name: normal growth on mercaptoethanol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mercaptoethanol." [PomBase:mah] synonym: "normal cell population growth in presence of mercaptoethanol" EXACT [PomBase:mah] synonym: "normal cell population growth on 2-sulfanylethanol" EXACT [CHEBI:41218] synonym: "normal cell population growth on mercaptoethanol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to mercaptoethanol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on mercaptoethanol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:25:12Z [Term] id: FYPO:0000959 name: normal growth on sodium dodecyl sulfate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium dodecyl sulfate (SDS." [PomBase:mah] synonym: "normal cell population growth in presence of sodium dodecyl sulfate" EXACT [PomBase:mah] synonym: "normal cell population growth on SDS" EXACT [CHEBI:8984] synonym: "normal cell population growth on sodium dodecyl sulfate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to sodium dodecyl sulfate" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on sodium dodecyl sulphate" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on sodium dodecyl sulfate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:28:02Z [Term] id: FYPO:0000960 name: normal growth on ethanol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethanol." [PomBase:mah] synonym: "normal cell population growth in presence of ethanol" EXACT [PomBase:mah] synonym: "normal cell population growth on ethanol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on to ethyl alcohol" EXACT [PomBase:mah] synonym: "normal cellular response to ethanol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on ethanol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:35:28Z [Term] id: FYPO:0000961 name: normal growth on sorbitol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sorbitol." [PomBase:mah] synonym: "normal cell population growth in presence of sorbitol" EXACT [PomBase:mah] synonym: "normal cell population growth on glucitol" EXACT [CHEBI:30199] synonym: "normal cell population growth on sorbitol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to sorbitol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on sorbitol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:36:31Z [Term] id: FYPO:0000962 name: normal growth on hydrogen peroxide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydrogen peroxide." [PomBase:mah] synonym: "normal cell population growth in presence of hydrogen peroxide" EXACT [PomBase:mah] synonym: "normal cell population growth on H2O2" EXACT [CHEBI:16240] synonym: "normal cell population growth on hydrogen peroxide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to hydrogen peroxide" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:37:24Z [Term] id: FYPO:0000963 name: normal growth on hydroxyurea def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydroxyurea." [PomBase:mah] synonym: "normal cell population growth in presence of hydroxyurea" EXACT [PomBase:mah] synonym: "normal cell population growth on HU" EXACT [PomBase:mah] synonym: "normal cell population growth on hydroxyurea" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:38:22Z [Term] id: FYPO:0000964 name: normal growth on thiabendazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing thiabendazole." [PomBase:mah] synonym: "normal cell population growth in presence of thiabendazole" EXACT [PomBase:mah] synonym: "normal cell population growth on TBZ" EXACT [CHEBI:45979] synonym: "normal cell population growth on thiabendazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to thiabendazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on thiabendazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:39:39Z [Term] id: FYPO:0000965 name: abnormal histone H3-K14 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3K14 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000788 ! abnormal histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2012-04-12T12:56:33Z [Term] id: FYPO:0000966 name: increased histone H3-K14 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K14 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K14 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3K14 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000965 ! abnormal histone H3-K14 acetylation at centromere outer repeat during vegetative growth is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2012-04-12T02:31:26Z [Term] id: FYPO:0000967 name: decreased histone H3-K14 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3K14 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0044154, PomBase:vw] synonym: "reduced histone H3-K14 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0000965 ! abnormal histone H3-K14 acetylation at centromere outer repeat during vegetative growth is_a: FYPO:0001458 ! decreased histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2012-04-12T02:32:04Z [Term] id: FYPO:0000968 name: normal cellular response to stress during vegetative growth def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to stress during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0005191 ! normal cellular response to stress created_by: midori creation_date: 2012-04-19T01:25:21Z [Term] id: FYPO:0000969 name: normal growth during cellular response to UV def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to ultraviolet light." [PomBase:mah] synonym: "normal cell population growth during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal cell population growth during cellular response to UV" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to UV" RELATED [PomBase:mah] synonym: "normal sensitivity to UV irradiation" RELATED [PomBase:vw] synonym: "normal vegetative cell population growth during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T01:25:40Z [Term] id: FYPO:0000970 name: sensitive to mitomycin C def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mitomycin C. Cells stop growing (and may die) at a concentration of mitomycin C that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mitomycin C" EXACT [PomBase:mah] synonym: "sensitive to mitomycin C during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to mitomycin C during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-04-19T01:38:22Z [Term] id: FYPO:0000972 name: increased number of Rad52 foci during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal." [PMID:22064477, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth is_a: FYPO:0004709 ! increased number of Rad52 foci created_by: midori creation_date: 2012-04-19T02:09:54Z [Term] id: FYPO:0000973 name: normal cellular response to copper ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to copper ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to copper" EXACT [GO:0071280] synonym: "normal cellular response to copper ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to copper ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:30:26Z [Term] id: FYPO:0000974 name: normal cellular response to zinc ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to zinc ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to zinc" EXACT [GO:0071294] synonym: "normal cellular response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:31:30Z [Term] id: FYPO:0000975 name: normal cellular response to mercury ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to mercury ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to mercury" EXACT [GO:0071248] synonym: "normal cellular response to mercury ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to mercury ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:32:52Z [Term] id: FYPO:0000976 name: normal cellular response to selenite ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to selenite ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to selenite" EXACT [PomBase:mah] synonym: "normal cellular response to selenite ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to selenite ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:33:28Z [Term] id: FYPO:0000977 name: normal cellular response to silver ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to silver ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to silver ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to silver ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:34:05Z [Term] id: FYPO:0000978 name: normal growth on mevastatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mevastatin." [PomBase:mah] synonym: "normal cell population growth on compactin" EXACT [PomBase:al] synonym: "normal cell population growth on mevastatin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on mevastatin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T04:43:12Z [Term] id: FYPO:0000979 name: normal growth on miconazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing miconazole." [PomBase:mah] synonym: "normal cell population growth on miconazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on miconazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T04:45:21Z [Term] id: FYPO:0000980 name: normal growth on amphotericin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amphotericin B." [PomBase:mah] synonym: "normal cell population growth on amphotericin B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on amphotericin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T04:46:40Z [Term] id: FYPO:0000981 name: normal glutamate dehydrogenase (NAD+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAD+ as a cofactor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal NAD-GDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-04-20T02:09:01Z [Term] id: FYPO:0000982 name: abnormal glutamate dehydrogenase (NADP+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is abnormal." [PomBase:mah] synonym: "abnormal NAD(P)H-dependent glutamate dehydrogenase activity" EXACT [GO:0004354] synonym: "abnormal NADP-GDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-20T02:12:39Z [Term] id: FYPO:0000983 name: decreased glutamate dehydrogenase (NADP+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is decreased." [PomBase:mah] synonym: "decreased NAD(P)H-dependent glutamate dehydrogenase activity" EXACT [GO:0004354] synonym: "decreased NADP-GDH activity" EXACT [PMID:7851743, PomBase:al] synonym: "reduced glutamate dehydrogenase (NADP+) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000982 ! abnormal glutamate dehydrogenase (NADP+) activity created_by: midori creation_date: 2012-04-20T02:12:45Z [Term] id: FYPO:0000984 name: abnormal transcriptional response to pheromone def: "A conjugation phenotype in which regulation of transcription in response to mating pheromone is abnormal." [PomBase:mah] synonym: "abnormal regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0046019, PomBase:mah] is_a: FYPO:0000302 ! abnormal response to pheromone created_by: midori creation_date: 2012-04-25T12:26:50Z [Term] id: FYPO:0000985 name: obsolete transcriptional response to pheromone at increased pheromone level def: "OBSOLETE. A cellular response phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter occurs only at a higher level of pheromone than normal." [PomBase:mah] comment: This term was made obsolete because it has a confusing name and represents a non-useful distinction. synonym: "decreased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "decreased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "positive regulation of transcription from RNA polymerase II promoter by pheromones at increased pheromone level" EXACT [GO:0007329, PomBase:mah] synonym: "resistant to pheromone" RELATED [PomBase:al, PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-04-25T12:29:45Z [Term] id: FYPO:0000986 name: obsolete increased transcriptional response to pheromone at normal pheromone level def: "OBSOLETE. A cellular response phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter results in a higher-than-normal level of transcription at a given pheromone level." [PomBase:mah] comment: This term was made obsolete because it has a confusing name and represents a non-useful distinction. synonym: "increased positive regulation of transcription from RNA polymerase II promoter by pheromones at normal pheromone level" EXACT [GO:0007329, PomBase:mah] synonym: "increased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "increased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "sensitive to pheromone" RELATED [PomBase:al, PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-04-25T12:34:59Z [Term] id: FYPO:0000987 name: obsolete decreased transcriptional response to pheromone at normal pheromone level def: "OBSOLETE. A cellular response phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter results in a lower-than-normal level of transcription at a given pheromone level." [PomBase:mah] comment: This term was made obsolete because it has a confusing name and represents a non-useful distinction. synonym: "decreased positive regulation of transcription from RNA polymerase II promoter by pheromones at normal pheromone level" EXACT [GO:0007329, PomBase:mah] synonym: "decreased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "decreased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "reduced transcriptional response to pheromone at normal pheromone level" EXACT [PomBase:mah] synonym: "resistant to pheromone" RELATED [PomBase:al, PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-04-25T12:49:41Z [Term] id: FYPO:0000988 name: normal cellular response to arsenic def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to arsenic is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to arsenic during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to arsenic during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-25T01:27:55Z [Term] id: FYPO:0000989 name: altered level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell differs from normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal level of substance in cell" EXACT [PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2012-04-25T02:06:49Z [Term] id: FYPO:0000990 name: increased level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "increased accumulation of substance in cell" RELATED [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-04-25T02:07:28Z [Term] id: FYPO:0000991 name: decreased level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is lower than normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "reduced level of substance in cell" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-04-25T02:08:00Z [Term] id: FYPO:0000992 name: altered cellular phosphatidylinositol-3-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular phosphatidylinositol-3-phosphate level" EXACT [PomBase:mah] synonym: "altered cellular phosphatidylinositol-3-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered cellular phosphatidylinositol-3-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular PI(3)P level" EXACT [PomBase:vw] synonym: "altered cellular PI-3-P level" EXACT [PomBase:al] synonym: "altered PI-3-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001287 ! altered phospholipid level created_by: midori creation_date: 2012-04-25T02:15:24Z [Term] id: FYPO:0000993 name: decreased cellular phosphatidylinositol-3-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-3-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-3-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PI(3)P level" EXACT [PomBase:vw] synonym: "decreased cellular PI-3-P level" EXACT [PomBase:al] synonym: "decreased PI-3-P accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphatidylinositol-3-phosphate level" EXACT [PomBase:mah] is_a: FYPO:0000992 ! altered cellular phosphatidylinositol-3-phosphate level is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-04-25T02:18:12Z [Term] id: FYPO:0000994 name: increased cellular phosphatidylinositol-4-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phosphatidylinositol-4-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphatidylinositol-4-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PI(4)P level" EXACT [PomBase:vw] synonym: "increased cellular PI-4-P level" EXACT [PomBase:al] synonym: "increased PI-4-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001015 ! altered cellular phosphatidylinositol-4-phosphate level is_a: FYPO:0001286 ! increased cellular phosphoinositide level created_by: midori creation_date: 2012-04-25T02:19:52Z [Term] id: FYPO:0000995 name: abnormal cell morphology during nitrogen starvation def: "A cell phenotype in which cell morphology (i.e. the size, shape, or structure of the cell) is altered when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal cell morphology during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal cell morphology during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2012-04-25T02:40:49Z [Term] id: FYPO:0000996 name: tapered cell during nitrogen starvation def: "A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other when the cell is subject to nitrogen starvation. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. Note that the difference between 'tapered cell' (FYPO:0000014) and 'spindle-shaped cell' (FYPO:0007230) is that a tapered cell is narrow at only one end, whereas a spindle-shaped cell is narrow at both ends. synonym: "bottle-shaped cell during nitrogen starvation" EXACT [PomBase:vw] synonym: "cell morphology, bottle/skittle during nitrogen starvation" EXACT [PomBase:mah] synonym: "skittle-shaped cell during nitrogen starvation" EXACT [PomBase:mah] synonym: "tapered cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "tapered cell during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000014 ! tapered cell is_a: FYPO:0000995 ! abnormal cell morphology during nitrogen starvation created_by: midori creation_date: 2012-04-25T02:41:14Z [Term] id: FYPO:0000997 name: pear-shaped cell during nitrogen starvation def: "A cell morphology phenotype in which a cell is shaped in the form of a pear when the cell is subject to nitrogen starvation. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "cell morphology, pear shaped during nitrogen starvation" EXACT [PomBase:mah] synonym: "ice cream cone-shaped cell during nitrogen starvation" EXACT [PMID:2236039, PomBase:vw] synonym: "pear-shaped cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "pear-shaped cell during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000020 ! pear-shaped cell is_a: FYPO:0000995 ! abnormal cell morphology during nitrogen starvation created_by: midori creation_date: 2012-04-25T02:41:20Z [Term] id: FYPO:0000998 name: elongated cell during nitrogen starvation def: "A cell morphology phenotype in which a cell becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: Note that wild-type cells become shorter under nitrogen starvation conditions than under nitrogen-replete conditions, and that mutant cells subjected to nitrogen starvation may have lengths similar to wild type cells under non-starved conditions. Also note that this term is classified as a type of abnormal cell shape, because under a given set of conditions wild-type cells are never seen with the proportions (length:diameter ratio) observed in elongated cells. Small cells, in contrast, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "cell morphology, elongated cell during nitrogen starvation" EXACT [PomBase:mah] synonym: "elongated cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "elongated cell during nitrogen deprivation" EXACT [PomBase:vw] synonym: "gain of polarization during quiescence" RELATED [PMID:27746023] synonym: "long cell during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0000995 ! abnormal cell morphology during nitrogen starvation created_by: midori creation_date: 2012-04-25T02:41:23Z [Term] id: FYPO:0000999 name: enlarged nucleus during nitrogen starvation def: "A physical cellular phenotype in which the nucleus is larger than normal when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "enlarged nuclei during nitrogen starvation" EXACT [PomBase:vw] synonym: "enlarged nucleus during nitrogen depletion" EXACT [PomBase:vw] synonym: "enlarged nucleus during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002255 ! enlarged nucleus created_by: midori creation_date: 2012-04-25T03:07:07Z [Term] id: FYPO:0001000 name: normal cell cycle arrest in mitotic G1 phase during nitrogen starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally in G1 phase when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "mitotic G1 phase arrest during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal cell cycle arrest in mitotic G1 phase during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal cell cycle arrest in mitotic G1 phase during nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal mitotic cell cycle arrest in G1 phase during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000711 ! decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation is_a: FYPO:0001025 ! normally arrested mitotic cell cycle progression created_by: midori creation_date: 2012-04-25T03:36:56Z [Term] id: FYPO:0001001 name: abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition, instead of the normal G1 phase, when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal cell cycle arrest in mitotic G2 phase during nitrogen starvation" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished mitotic G2/M phase transition during nitrogen starvation" RELATED [PomBase:mah] synonym: "advanced nitrogen deprivation-induced G1 arrest" RELATED [PomBase:vw] synonym: "cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation" EXACT [PomBase:mah] synonym: "mitotic G2/M phase transition arrest during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000710 ! abnormal mitotic cell cycle arrest in response to nitrogen starvation is_a: FYPO:0001151 ! cell cycle arrest at mitotic G2/M phase transition during starvation created_by: midori creation_date: 2012-04-25T03:39:33Z [Term] id: FYPO:0001002 name: abolished cell division prior to G0 entry def: "A cellular process phenotype in which a cell does not undergo the normal two rounds of cell division prior to entering quiescence (G0)." [PMID:19366728, PomBase:mah] synonym: "cell division prior to G0 entry abolished" EXACT [PomBase:mah] synonym: "loss of pre-quiescence cell divisions following nitrogen starvation" EXACT [PomBase:al] is_a: FYPO:0000427 ! abnormal G1 to G0 transition created_by: midori creation_date: 2012-04-25T03:42:48Z [Term] id: FYPO:0001003 name: small vacuoles present in increased numbers during nitrogen starvation def: "A cell phenotype in which a cell contains more, but smaller, vacuoles than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "fragmented vacuoles during nitrogen starvation" RELATED [PomBase:mah] synonym: "small vacuoles present in greater numbers during nitrogen starvation" EXACT [PomBase:mah] synonym: "small vacuoles present in increased numbers during nitrogen depletion" EXACT [PomBase:vw] synonym: "small vacuoles present in increased numbers during nitrogen deprivation" EXACT [PomBase:vw] synonym: "vacuole organization defects, fragmented vacuoles during nitrogen starvation" RELATED [PomBase:mah] synonym: "vacuoles present in increased numbers, with decreased vacuole size, during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0002258 ! small vacuoles present in increased numbers relationship: has_part FYPO:0006053 ! lipid droplets present in spore cytoplasm in decreased numbers, mislocalized to ascus epiplasm created_by: midori creation_date: 2012-04-25T03:48:58Z [Term] id: FYPO:0001004 name: viable upon G0 to G1 transition def: "A cell phenotype in which cells to resume growth normally upon exiting G0 phase." [PMID:19366728, PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-04-25T03:50:33Z [Term] id: FYPO:0001005 name: fragmented DNA during nitrogen starvation def: "A cell phenotype in which DNA is broken into small fragments when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. Use 'fragmented DNA' (FYPO:0000160) or one of its descendants if DNA was detected using a method that can resolve molecule sizes (e.g. gel electrophoresis) or detect DNA ends (e.g. TUNEL assay). Otherwise, consider using 'fragmented nucleus' (FYPO:0001919) or one of its descendants. synonym: "DNA fragmentation during nitrogen starvation" EXACT [PomBase:mah] synonym: "fragmented DNA during nitrogen depletion" EXACT [PomBase:vw] synonym: "fragmented DNA during nitrogen deprivation" EXACT [PomBase:vw] synonym: "fragmented nucleus during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000160 ! fragmented DNA created_by: midori creation_date: 2012-04-25T04:01:19Z [Term] id: FYPO:0001006 name: inviable elongated multinucleate vegetative cell with central constriction def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus, is elongated, is inviable, and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In a cell with this phenotype, the diameter at the ends may be much greater than in wild-type cells. Septal material may accumulate in patches at the cell surface, but no septum forms." [PMID:8834798, PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated, multinucleate dumbbell-shaped cell" RELATED [PomBase:mah] synonym: "inviable elongated multinucleate cell with central constriction during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated multinucleate vegetative cell with central constriction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated multinucleate vegetative cell with constricted region at cell division site" EXACT [PomBase:vw] synonym: "inviable, elongated, multinucleate dumbbell-shaped vegetative cell" RELATED [PomBase:mah] synonym: "lethal; elongated multinucleate vegetative cell with central constriction" EXACT [PomBase:mah] synonym: "long, multinucleate dumbbell-shaped cell" RELATED [PomBase:vw] synonym: "multinucleate dumbbell-shaped cell" RELATED [PomBase:mah] is_a: FYPO:0002024 ! inviable elongated multinucleate aseptate vegetative cell relationship: has_part FYPO:0000779 ! inviable elongated vegetative cell with central constriction created_by: midori creation_date: 2012-04-25T04:07:50Z [Term] id: FYPO:0001007 name: normal mitosis def: "A cellular process phenotype in which mitosis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitosis: normal" EXACT [PomBase:mah] synonym: "normal mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-04-25T04:16:58Z [Term] id: FYPO:0001008 name: actomyosin contractile ring absent def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the actomyosin contractile ring is absent from the cell." [PomBase:mah] comment: In the absence of filamentous actin, a ring structure may form, but is not considered a contractile ring. synonym: "actomyosin contractile ring absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actomyosin contractile ring absent during vegetative growth" EXACT [PomBase:mah] synonym: "actomyosin contractile ring absent from cell" EXACT [PomBase:mah] synonym: "actomyosin contractile ring actin absent" NARROW [PomBase:mah] synonym: "contractile ring absent" EXACT [PomBase:vw] synonym: "cytokinetic contractile ring absent" EXACT [PomBase:vw] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2012-04-25T04:19:40Z [Term] id: FYPO:0001009 name: abolished actomyosin contractile ring assembly def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filaments and associated proteins does not occur, resulting in the failure to form an actomyosin contractile ring." [PMID:19713940, PomBase:mah] comment: Note that a ring structure may form without filamentous actin, but a ring lacking F-actin is not considered a contractile ring. synonym: "abolished actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:mah] synonym: "abolished contractile ring assembly" EXACT [PomBase:mah] synonym: "abolished cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "abolished cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "abolished cytokinetic ring formation" RELATED [PomBase:vw] synonym: "abolished mitotic contractile ring assembly" EXACT [PomBase:vw] synonym: "actomyosin contractile ring assembly abolished" EXACT [PomBase:mah] synonym: "cytokinesis defects, contractile ring actin, absent" RELATED [PomBase:mah] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly relationship: has_output FYPO:0001008 ! actomyosin contractile ring absent created_by: midori creation_date: 2012-04-25T04:37:10Z [Term] id: FYPO:0001010 name: abolished actin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of cytoskeletal structures comprising actin filaments does not occur." [PomBase:mah] synonym: "abolished actin filament organisation" EXACT [PomBase:mah] synonym: "abolished actin filament organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actin filament organization during vegetative growth" EXACT [PomBase:mah] synonym: "actin filament organization abolished" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth relationship: has_output FYPO:0001011 ! filamentous actin absent created_by: midori creation_date: 2012-04-25T04:55:17Z [Term] id: FYPO:0001011 name: filamentous actin absent def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain filamentous actin structures, such as cortical patches or dots, or rings." [PomBase:mah] synonym: "actin filaments absent" EXACT [PomBase:mah] synonym: "F-actin absent" EXACT [PomBase:mah] synonym: "filamentous actin absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "filamentous actin absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2012-04-25T04:58:49Z [Term] id: FYPO:0001012 name: growth auxotrophic for uracil def: "Auxotrophy in which a cell is unable to synthesize uracil, and therefore requires uracil in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for uracil during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for uracil during vegetative growth" EXACT [PomBase:mah] synonym: "uracil auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2012-04-26T12:15:11Z [Term] id: FYPO:0001013 name: abnormal membrane organization def: "A cellular process phenotype in which cellular membrane organization is abnormal. Cellular membrane organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid bilayer membrane, such as the plasma membrane or an organelle membrane." [GO:0061024, PomBase:mah] synonym: "abnormal cellular membrane organization" EXACT [GO:0061024, PomBase:mah] synonym: "abnormal membrane organisation" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2012-04-26T12:57:24Z [Term] id: FYPO:0001014 name: abnormal membrane organization during nitrogen starvation def: "A cellular process phenotype in which cellular membrane organization is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal cellular membrane organization during nitrogen starvation" EXACT [GO:0061024, PomBase:mah] synonym: "abnormal membrane organisation during nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal membrane organization during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal membrane organization during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0001013 ! abnormal membrane organization created_by: midori creation_date: 2012-04-26T12:59:57Z [Term] id: FYPO:0001015 name: altered cellular phosphatidylinositol-4-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular phosphatidylinositol-4-phosphate level" EXACT [PomBase:mah] synonym: "altered cellular phosphatidylinositol-4-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered cellular phosphatidylinositol-4-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular PI(4)P level" EXACT [PomBase:vw] synonym: "altered cellular PI-4-P level" EXACT [PomBase:al] synonym: "altered PI-4-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001287 ! altered phospholipid level created_by: midori creation_date: 2012-04-25T02:15:24Z [Term] id: FYPO:0001016 name: normal growth on actinomycin D def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing actinomycin D." [PomBase:mah] synonym: "normal cell population growth in presence of actinomycin D" EXACT [PomBase:mah] synonym: "normal cell population growth on actinomycin D" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to actinomycin D" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on actinomycin D" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-26T03:36:00Z [Term] id: FYPO:0001017 name: premature NETO def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) begins earlier than normal." [PomBase:mah] synonym: "advanced NETO" EXACT [PomBase:mah] synonym: "early NETO" EXACT [PomBase:mah] synonym: "premature activation of bipolar cell growth" RELATED [PomBase:mah] synonym: "premature cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "premature NETO during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature NETO during vegetative growth" EXACT [PomBase:mah] synonym: "premature new end take-off" EXACT [PomBase:mah] synonym: "premature switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] is_a: FYPO:0000147 ! abnormal NETO created_by: midori creation_date: 2012-04-30T11:46:57Z [Term] id: FYPO:0001018 name: abolished NETO def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) does not occur." [PomBase:mah] synonym: "abolished activation of bipolar cell growth" RELATED [PomBase:mah] synonym: "abolished cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "abolished NETO during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished NETO during vegetative growth" EXACT [PomBase:mah] synonym: "abolished new end take-off" EXACT [PomBase:mah] synonym: "abolished switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] synonym: "absence of NETO" EXACT [PomBase:vw] synonym: "NETO abolished" EXACT [PomBase:mah] is_a: FYPO:0000147 ! abnormal NETO relationship: has_output FYPO:0001391 ! mislocalized septum, near new end created_by: midori creation_date: 2012-04-30T11:49:16Z [Term] id: FYPO:0001019 name: monopolar actin cortical patch localization during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only one end of a cell." [PomBase:mah] synonym: "monopolar actin cortical patch localisation during vegetative growth" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "monopolar actin cortical patch location during vegetative growth" RELATED [PomBase:mah] synonym: "monopolar actin patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "monopolar F-actin patch localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003988 ! mislocalized actin cortical patches during vegetative growth created_by: midori creation_date: 2012-04-30T02:17:33Z [Term] id: FYPO:0001020 name: normal growth on calcium def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing calcium ions." [PomBase:mah] synonym: "normal cell population growth in presence of calcium ions" EXACT [PomBase:mah] synonym: "normal cell population growth on calcium" EXACT [PomBase:mah] synonym: "normal cell population growth on calcium ion" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to calcium ion" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on calcium ion" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on calcium ion" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-30T02:48:06Z [Term] id: FYPO:0001021 name: normal growth during cellular response to osmotic stress def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to osmotic stress." [PomBase:mah] synonym: "normal cell population growth during cellular response to osmotic stress" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-30T02:50:20Z [Term] id: FYPO:0001022 name: normal growth during cellular response to high osmolarity def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to high osmolarity." [PomBase:mah] synonym: "normal cell population growth during cellular response to high osmolarity" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth during cellular response to hyperosmotic conditions" EXACT [PomBase:mah] synonym: "normal cellular response to high osmolarity" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to high osmolarity" EXACT [PomBase:mah] is_a: FYPO:0001021 ! normal growth during cellular response to osmotic stress created_by: midori creation_date: 2012-04-30T02:50:58Z [Term] id: FYPO:0001023 name: normal growth on cisplatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cisplatin." [PomBase:mah] synonym: "normal cell population growth in presence of cisplatin" EXACT [PomBase:mah] synonym: "normal cell population growth on cisplatin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cisplatin" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cis-DDP" EXACT [CHEBI:27899] synonym: "normal vegetative cell population growth on cisplatin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-30T02:59:00Z [Term] id: FYPO:0001024 name: cell cycle arrest phenotype def: "A cell cycle phenotype that affects or involves the normal or abnormal occurrence of cell cycle arrest. In cell cycle arrest, progression through the cell cycle is halted during one of the normal phases (G1, S, G2, or M)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast cell cycle arrest phenotype" EXACT [PomBase:mah] is_a: FYPO:0000631 ! cell cycle phenotype created_by: midori creation_date: 2012-05-09T01:15:41Z [Term] id: FYPO:0001025 name: normally arrested mitotic cell cycle progression def: "A cellular process phenotype in which mitotic cell cycle progression is arrested under conditions where arrest normally occurs." [PomBase:mah] synonym: "normal mitotic cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0004040 ! mitotic cell cycle arrest phenotype is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2012-05-09T01:38:00Z [Term] id: FYPO:0001026 name: abnormal occurrence of normal mitotic cell cycle arrest def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs is abnormal (does not occur, or occurs abnormally)." [PomBase:mah] is_a: FYPO:0002737 ! abnormal mitotic cell cycle process is_a: FYPO:0004040 ! mitotic cell cycle arrest phenotype created_by: midori creation_date: 2012-05-09T01:43:53Z [Term] id: FYPO:0001027 name: normal cell cycle arrest at mitotic G2/M phase transition during glucose starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally at the mitotic G2/M phase transition when the cell is subject to glucose starvation." [PomBase:al, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal cell cycle arrest at mitotic G2/M phase transition during glucose depletion" EXACT [PomBase:vw] synonym: "normal cell cycle arrest at mitotic G2/M phase transition during glucose deprivation" EXACT [PomBase:vw] synonym: "normal cell cycle arrest at mitotic G2/M phase transition during glucose limitation" RELATED [PomBase:mah] synonym: "normal cell cycle arrest in mitotic G2 phase during glucose starvation" RELATED [PomBase:mah] synonym: "normal mitotic cell cycle arrest at mitotic G2/M phase transition during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001025 ! normally arrested mitotic cell cycle progression is_a: FYPO:0001151 ! cell cycle arrest at mitotic G2/M phase transition during starvation created_by: midori creation_date: 2012-05-09T01:54:19Z [Term] id: FYPO:0001028 name: abnormal cell cycle arrest in mitotic interphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in any part of interphase, under conditions where arrest is not a normal occurrence." [PomBase:mah] comment: Use this term for terminal arrest. If arrest is transient, consider using 'delayed cell cycle phase transition' (FYPO:0000409) or one of its more specific descendants. synonym: "abnormal mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "abnormal mitotic interphase cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase created_by: midori creation_date: 2012-05-09T02:46:23Z [Term] id: FYPO:0001029 name: resistance to canavanine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of canavanine than normal." [PomBase:mah] synonym: "resistance to canavanine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to canavanine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to canavanine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-05-15T16:55:19Z [Term] id: FYPO:0001030 name: normal growth on dithiothreitol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing dithiothreitol." [PomBase:mah] synonym: "normal cell population growth in presence of dithiothreitol" EXACT [PomBase:mah] synonym: "normal cell population growth on 1,4-dithiothreitol" EXACT [CHEBI:18320] synonym: "normal cell population growth on dithiothreitol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on DTT" EXACT [PomBase:mah] synonym: "normal cellular response to dithiothreitol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on dithiothreitol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-05-09T04:26:29Z [Term] id: FYPO:0001031 name: accumulation of single-strand break sites def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of single-strand breaks in DNA is greater than normal." [PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad52 foci during vegetative growth' (FYPO:0000972). synonym: "accumulation of single-strand break sites during mitotic cell cycle" RELATED [PomBase:mah] synonym: "accumulation of single-strand break sites during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of single-strand break sites during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-05-09T04:33:36Z [Term] id: FYPO:0001032 name: resistance to camptothecin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of camptothecin than normal." [PomBase:mah] synonym: "resistance to camptothecin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to camptothecin" EXACT [PomBase:mah] synonym: "resistant to CPT" EXACT [CHEBI:27656, PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-05-09T04:35:09Z [Term] id: FYPO:0001033 name: normal double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal double-strand break repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-05-09T04:36:23Z [Term] id: FYPO:0001034 name: resistance to tunicamycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tunicamycin than normal." [PomBase:mah] synonym: "resistance to tunicamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tunicamycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to TM" EXACT [PomBase:al] synonym: "resistant to tunicamycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-05-09T04:43:09Z [Term] id: FYPO:0001035 name: increased cell wall thickness during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thicker than normal." [PomBase:mah] synonym: "increased cell wall thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "thickened cell wall during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006745 ! abnormal cell wall thickness during vegetative growth created_by: midori creation_date: 2012-05-09T04:44:26Z [Term] id: FYPO:0001036 name: delaminated cell wall during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off." [PomBase:al, PomBase:mah] synonym: "delaminate cell wall during vegetative growth" EXACT [PomBase:mah] synonym: "delaminated cell wall during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000351 ! abnormal cell wall morphology during vegetative growth is_a: FYPO:0002948 ! delaminated cell wall created_by: midori creation_date: 2012-05-09T04:45:40Z [Term] id: FYPO:0001037 name: normal growth during cellular response to salt stress def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to salt stress." [PomBase:mah] synonym: "normal cell population growth during cellular response to ionic osmotic stress" EXACT [GO:0071472, PomBase:mah] synonym: "normal cell population growth during cellular response to salt stress" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal cellular salinity response" RELATED [GO:0071472, PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001021 ! normal growth during cellular response to osmotic stress created_by: midori creation_date: 2012-05-09T04:57:53Z [Term] id: FYPO:0001038 name: increased protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification during vegetative growth is_a: FYPO:0000775 ! abnormal protein phosphorylation during vegetative growth is_a: FYPO:0002680 ! increased protein phosphorylation created_by: midori creation_date: 2012-05-09T05:01:01Z [Term] id: FYPO:0001039 name: abnormal thiamine diphosphokinase activity def: "A molecular function phenotype in which the observed rate of thiamine diphosphokinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-05-09T05:07:50Z [Term] id: FYPO:0001040 name: decreased thiamine diphosphokinase activity def: "A molecular function phenotype in which the observed rate of thiamine diphosphokinase activity is decreased." [PomBase:mah] synonym: "reduced thiamine diphosphokinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001039 ! abnormal thiamine diphosphokinase activity created_by: midori creation_date: 2012-05-09T05:07:58Z [Term] id: FYPO:0001041 name: increased cellular thiamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of thiamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular thiamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular thiamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular vitamin B1 level" EXACT [PomBase:mah] synonym: "increased thiamine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-09T05:09:40Z [Term] id: FYPO:0001042 name: inviable after spore germination, single or double cell division def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, single or double cell division" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division" EXACT [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2012-05-09T05:12:57Z [Term] id: FYPO:0001043 name: increased mating efficiency def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is higher than normal." [PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). synonym: "mating efficiency: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-05-09T05:15:28Z [Term] id: FYPO:0001044 name: abnormal acid phosphatase activity def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-05-10T04:20:28Z [Term] id: FYPO:0001045 name: decreased acid phosphatase activity def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is decreased." [PomBase:mah] synonym: "reduced acid phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001044 ! abnormal acid phosphatase activity created_by: midori creation_date: 2012-05-10T04:20:35Z [Term] id: FYPO:0001046 name: premature mitosis def: "A cellular process phenotype in which cells enter mitosis earlier, relative to cell size or DNA integrity checkpoint status, than normal." [PomBase:mah] comment: Use this term for any experiments that detect early mitosis by any criteria. If you have measured CDK activity or calculated the transition point, also consider using 'premature mitotic G2/M transition' (FYPO:0002516). Also consider annotating to 'viable small vegetative cell' (FYPO:0000648), if mitosis takes place when cells are smaller than normal. synonym: "advanced mitosis" EXACT [PomBase:mah] synonym: "early mitosis" EXACT [PomBase:mah] synonym: "premature mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001204 ! mistimed mitosis created_by: midori creation_date: 2012-05-11T01:28:00Z [Term] id: FYPO:0001047 name: obsolete mitotic catastrophe def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell proceeds through the mitotic metaphase/anaphase transition in the presence of an uncorrected problem (such as chromosome structure or kinetochore attachment), and as a result undergoes abnormal nuclear division and subsequently dies." [PomBase:mah] comment: This term was made obsolete because "mitotic catastrophe" has not been clearly defined for fission yeast. synonym: "mitotic catastrophe during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-05-11T01:34:45Z [Term] id: FYPO:0001049 name: obsolete mitotic catastrophe, small cell def: "OBSOLETE. An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when smaller than wild type." [PomBase:mah] comment: This term was made obsolete because "mitotic catastrophe" has not been clearly defined for fission yeast. synonym: "mitotic catastrophe, small cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe, small cell during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001052 created_by: midori creation_date: 2012-05-11T01:59:31Z [Term] id: FYPO:0001050 name: obsolete mitotic catastrophe, normal size cell def: "OBSOLETE. An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis at the same size as wild type." [PomBase:mah] comment: This term was made obsolete because "mitotic catastrophe" has not been clearly defined for fission yeast. synonym: "mitotic catastrophe, normal size cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe, normal size cell during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001053 created_by: midori creation_date: 2012-05-11T02:09:56Z [Term] id: FYPO:0001051 name: obsolete mitotic catastrophe, elongated cell def: "OBSOLETE. An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when longer than wild type." [PomBase:mah] comment: This term was made obsolete because "mitotic catastrophe" has not been clearly defined for fission yeast. synonym: "mitotic catastrophe, elongated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic catastrophe, long cell" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0001054 created_by: midori creation_date: 2012-05-11T02:16:25Z [Term] id: FYPO:0001052 name: cut, small cell def: "An inviable phenotype in which a cell enters mitosis when smaller than wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis such that the septum physically divides the nucleus into two parts." [PomBase:mah] synonym: "cut following advanced onset of mitosis" EXACT [PomBase:jh, PomBase:vw] synonym: "cut, small cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut, small cell during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, small cell" RELATED [PomBase:mah] synonym: "septation following abnormal nuclear division, small cell" EXACT [PomBase:vw] synonym: "small cut cell" EXACT [PomBase:mah] is_a: FYPO:0000951 ! inviable small vegetative cell is_a: FYPO:0003165 ! cut with abnormal chromosome segregation relationship: has_part FYPO:0000951 ! inviable small vegetative cell relationship: has_part FYPO:0003165 ! cut with abnormal chromosome segregation created_by: midori creation_date: 2012-05-11T02:38:12Z [Term] id: FYPO:0001053 name: cut, normal size cell def: "An inviable phenotype in which a cell enters mitosis at the same size as wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis such that the septum physically divides the nucleus into two parts." [PomBase:mah] synonym: "cut following normal onset of mitosis, normal size cell" EXACT [PomBase:jh, PomBase:vw] synonym: "cut with mitotic catastrophe, normal size cell" RELATED [PomBase:mah] synonym: "cut, normal size cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut, normal size cell during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal nuclear division, normal size cell" EXACT [PomBase:vw] is_a: FYPO:0001124 ! normal vegetative cell size is_a: FYPO:0003165 ! cut with abnormal chromosome segregation relationship: has_part FYPO:0001124 ! normal vegetative cell size relationship: has_part FYPO:0003165 ! cut with abnormal chromosome segregation created_by: midori creation_date: 2012-05-11T02:39:40Z [Term] id: FYPO:0001054 name: cut, elongated cell def: "An inviable phenotype in which a cell enters mitosis when longer than wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis such that the septum physically divides the nucleus into two parts." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cut following delayed onset of mitosis" EXACT [PomBase:jh, PomBase:vw] synonym: "cut with mitotic catastrophe, elongated cell" RELATED [PomBase:mah] synonym: "cut, elongated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "cut, long cell" EXACT [PomBase:mah] synonym: "elongated cut cell" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, elongated cell" RELATED [PomBase:vw] synonym: "septation following abnormal nuclear division, long cell" EXACT [PomBase:vw] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0003165 ! cut with abnormal chromosome segregation relationship: has_part FYPO:0001490 ! inviable elongated vegetative cell relationship: has_part FYPO:0003165 ! cut with abnormal chromosome segregation created_by: midori creation_date: 2012-05-11T02:39:47Z [Term] id: FYPO:0001055 name: cut following normal mitotic chromosome condensation def: "An inviable phenotype in which a cell enters mitosis normally, in that the spindle forms normally and chromosomes condense normally, but then undergoes septation despite abnormal chromosome segregation, giving rise to a cut phenotype." [PomBase:mah, PomBase:vw] synonym: "cut following normal chromosome condensation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cut following normal entry into mitosis" RELATED [PomBase:mah] synonym: "cut following normal mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] synonym: "cut following normal mitotic entry" RELATED [PomBase:mah] synonym: "cut with normal mitotic chromosome condensation" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation, with normal chromosome condensation" EXACT [PomBase:vw] is_a: FYPO:0000229 ! cut created_by: midori creation_date: 2012-05-11T02:46:40Z [Term] id: FYPO:0001056 name: normal arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-arginine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal arginine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal arginine import into cell" EXACT [PomBase:al] synonym: "normal L-arginine import" EXACT [PomBase:mah] synonym: "normal L-arginine import across plasma membrane" EXACT [GO:0097638] synonym: "normal L-arginine uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-05-11T03:49:08Z [Term] id: FYPO:0001057 name: abnormal amino acid import def: "A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal." [PomBase:mah] synonym: "abnormal amino acid import across plasma membrane" EXACT [GO:0089718] synonym: "abnormal amino acid import into cell" EXACT [PomBase:al] synonym: "abnormal amino acid uptake" EXACT [PomBase:mah] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-05-11T03:54:42Z [Term] id: FYPO:0001058 name: decreased amino acid import def: "A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased amino acid import across plasma membrane" EXACT [GO:0089718] synonym: "decreased amino acid import into cell" EXACT [PomBase:al] synonym: "decreased amino acid uptake" EXACT [PomBase:mah] synonym: "reduced amino acid import" EXACT [PomBase:mah] is_a: FYPO:0001057 ! abnormal amino acid import created_by: midori creation_date: 2012-05-11T03:55:46Z [Term] id: FYPO:0001059 name: abnormal glutamate import during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamate into the cell is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal glutamate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal glutamate import into cell during vegetative growth" EXACT [PomBase:al] synonym: "abnormal glutamate uptake during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal L-glutamate import across plasma membrane during vegetative growth" EXACT [GO:0098712] synonym: "abnormal L-glutamate import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth is_a: FYPO:0001646 ! abnormal glutamate import created_by: midori creation_date: 2012-05-11T03:57:30Z [Term] id: FYPO:0001060 name: decreased glutamate import during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamate into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased glutamate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased glutamate import into cell during vegetative growth" EXACT [PomBase:al] synonym: "decreased glutamate uptake during vegetative growth" EXACT [PomBase:mah] synonym: "decreased L-glutamate import across plasma membrane during vegetative growth" EXACT [GO:0098712] synonym: "decreased L-glutamate import during vegetative growth" EXACT [PomBase:mah] synonym: "reduced glutamate import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001059 ! abnormal glutamate import during vegetative growth is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001649 ! decreased glutamate import created_by: midori creation_date: 2012-05-11T04:06:25Z [Term] id: FYPO:0001061 name: abnormal glutamine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamine into the cell is abnormal." [PomBase:mah] synonym: "abnormal glutamine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal glutamine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal glutamine import into cell" EXACT [PomBase:al] synonym: "abnormal glutamine uptake" EXACT [PomBase:mah] synonym: "abnormal L-glutamine import" NARROW [PomBase:mah] synonym: "abnormal L-glutamine import across plasma membrane" EXACT [GO:1903803] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:08:09Z [Term] id: FYPO:0001062 name: decreased glutamine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased glutamine import across plasma membrane" EXACT [GO:1903803] synonym: "decreased glutamine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased glutamine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glutamine import into cell" EXACT [PomBase:al] synonym: "decreased glutamine uptake" EXACT [PomBase:mah] synonym: "decreased L-glutamine import" NARROW [PomBase:mah] synonym: "reduced glutamine import" EXACT [PomBase:mah] is_a: FYPO:0001061 ! abnormal glutamine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:08:19Z [Term] id: FYPO:0001063 name: abnormal glycine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glycine into the cell is abnormal." [PomBase:mah] synonym: "abnormal glycine import across plasma membrane" EXACT [GO:1903804] synonym: "abnormal glycine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal glycine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal glycine import into cell" EXACT [PomBase:al] synonym: "abnormal glycine uptake" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:10:09Z [Term] id: FYPO:0001064 name: decreased glycine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glycine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased glycine import across plasma membrane" EXACT [GO:1903804] synonym: "decreased glycine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased glycine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glycine import into cell" EXACT [PomBase:al] synonym: "decreased glycine uptake" EXACT [PomBase:mah] synonym: "reduced glycine import" EXACT [PomBase:mah] is_a: FYPO:0001063 ! abnormal glycine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:10:17Z [Term] id: FYPO:0001065 name: abnormal threonine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of threonine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-threonine import" EXACT [PomBase:mah] synonym: "abnormal L-threonine import across plasma membrane" EXACT [GO:1903807] synonym: "abnormal threonine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal threonine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal threonine import into cell" EXACT [PomBase:al] synonym: "abnormal threonine uptake" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:11:34Z [Term] id: FYPO:0001066 name: decreased threonine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of threonine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-threonine import" EXACT [PomBase:mah] synonym: "decreased L-threonine import across plasma membrane" EXACT [GO:1903807] synonym: "decreased threonine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased threonine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased threonine import into cell" EXACT [PomBase:al] synonym: "decreased threonine uptake" EXACT [PomBase:mah] synonym: "reduced threonine import" EXACT [PomBase:mah] is_a: FYPO:0001065 ! abnormal threonine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:11:43Z [Term] id: FYPO:0001067 name: abnormal tyrosine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of tyrosine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-tyrosine import" EXACT [PomBase:mah] synonym: "abnormal L-tyrosine import across plasma membrane" EXACT [GO:1903808] synonym: "abnormal tyrosine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tyrosine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal tyrosine import into cell" EXACT [PomBase:al] synonym: "abnormal tyrosine uptake" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:14:15Z [Term] id: FYPO:0001068 name: decreased tyrosine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of tyrosine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-tyrosine import" EXACT [PomBase:mah] synonym: "decreased L-tyrosine import across plasma membrane" EXACT [GO:1903808] synonym: "decreased tyrosine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tyrosine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tyrosine import into cell" EXACT [PomBase:al] synonym: "decreased tyrosine uptake" EXACT [PomBase:mah] synonym: "reduced tyrosine import" EXACT [PomBase:mah] is_a: FYPO:0001067 ! abnormal tyrosine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:14:20Z [Term] id: FYPO:0001069 name: increased duration of mitotic cell cycle phase def: "A cellular process phenotype in which the duration of one or more mitotic cell cycle phases is longer than normal." [PomBase:mah] synonym: "increased duration of mitotic cell cycle phase during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged mitotic cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0000408 ! increased duration of cell cycle phase is_a: FYPO:0002736 ! abnormal mitotic cell cycle phase created_by: midori creation_date: 2012-05-31T14:19:07Z [Term] id: FYPO:0001070 name: decreased duration of mitotic cell cycle phase def: "A cellular process phenotype in which the duration of one or more mitotic cell cycle phases is shorter than normal." [PomBase:mah] synonym: "decreased duration of mitotic cell cycle phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced duration of mitotic cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0000410 ! decreased duration of cell cycle phase is_a: FYPO:0002736 ! abnormal mitotic cell cycle phase created_by: midori creation_date: 2012-05-31T14:19:54Z [Term] id: FYPO:0001071 name: normal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth created_by: midori creation_date: 2012-05-31T15:46:37Z [Term] id: FYPO:0001072 name: normal myo-inositol import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which myo-inositol import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal myo-inositol import across plasma membrane" EXACT [GO:1904679] synonym: "normal myo-inositol import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal myo-inositol import during vegetative growth" EXACT [PomBase:mah] synonym: "normal myo-inositol import into cell" EXACT [PomBase:al] synonym: "normal myo-inositol uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-05-31T15:59:13Z [Term] id: FYPO:0001073 name: abnormal myo-inositol import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of myo-inositol into the cell is abnormal." [PomBase:mah] synonym: "abnormal myo-inositol import across plasma membrane" EXACT [GO:1904679] synonym: "abnormal myo-inositol import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal myo-inositol import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal myo-inositol import into cell" EXACT [PomBase:al] synonym: "abnormal myo-inositol uptake" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-05-31T16:00:28Z [Term] id: FYPO:0001074 name: decreased myo-inositol import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of myo-inositol into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased myo-inositol import across plasma membrane" EXACT [GO:1904679] synonym: "decreased myo-inositol import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased myo-inositol import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased myo-inositol import into cell" EXACT [PomBase:al] synonym: "decreased myo-inositol uptake" EXACT [PomBase:mah] synonym: "reduced myo-inositol import" EXACT [PomBase:mah] is_a: FYPO:0001073 ! abnormal myo-inositol import created_by: midori creation_date: 2012-05-31T16:00:49Z [Term] id: FYPO:0001075 name: normal growth on papulacandin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papulacandin B." [PomBase:mah] synonym: "normal cell population growth in presence of papulacandin B" EXACT [PomBase:mah] synonym: "normal cell population growth on papulacandin B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to papulacandin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on papulacandin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-05-31T16:05:26Z [Term] id: FYPO:0001076 name: normal level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-05-31T16:27:42Z [Term] id: FYPO:0001077 name: normal polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal polysaccharide accumulation" RELATED [PomBase:mah] synonym: "normal polysaccharide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal polysaccharide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:29:26Z [Term] id: FYPO:0001078 name: normal beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "normal beta-glucan accumulation" RELATED [PomBase:mah] synonym: "normal beta-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular beta-glucan level" EXACT [PomBase:al] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-05-31T16:30:57Z [Term] id: FYPO:0001079 name: normal galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular galactomannan level" EXACT [PomBase:al] synonym: "normal galactomannan accumulation" RELATED [PomBase:mah] synonym: "normal galactomannan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal galactomannan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-05-31T16:33:06Z [Term] id: FYPO:0001080 name: decreased polysaccharide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular polysaccharide level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased polysaccharide accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased polysaccharide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced polysaccharide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001085 ! altered polysaccharide level during vegetative growth is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:33:42Z [Term] id: FYPO:0001081 name: decreased cell wall alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "decreased cell wall alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall alpha-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell wall alpha-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall alpha-glucan level" EXACT [PomBase:mah] is_a: FYPO:0002266 ! decreased cell wall polysaccharide level created_by: midori creation_date: 2012-05-31T16:35:00Z [Term] id: FYPO:0001082 name: decreased cell wall beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "decreased cell wall beta-glucan accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall beta-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell wall beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall beta-glucan level" EXACT [PomBase:mah] is_a: FYPO:0002266 ! decreased cell wall polysaccharide level created_by: midori creation_date: 2012-05-31T16:36:19Z [Term] id: FYPO:0001083 name: increased polysaccharide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is greater than normal." [PomBase:mah] synonym: "increased cellular polysaccharide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased polysaccharide accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased polysaccharide level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001085 ! altered polysaccharide level during vegetative growth is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:37:01Z [Term] id: FYPO:0001084 name: increased cell wall alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is greater than normal." [PomBase:mah] synonym: "increased cell wall alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "increased cell wall alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "increased cell wall alpha-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell wall alpha-glucan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-05-31T16:37:12Z [Term] id: FYPO:0001085 name: altered polysaccharide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal polysaccharide level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular polysaccharide level during vegetative growth" EXACT [PomBase:mah] synonym: "altered polysaccharide level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:39:05Z [Term] id: FYPO:0001086 name: normal glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-05-31T16:41:20Z [Term] id: FYPO:0001087 name: abnormal glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-05-31T16:41:54Z [Term] id: FYPO:0001088 name: decreased glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is decreased." [PomBase:mah] synonym: "reduced glucosyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001087 ! abnormal glucosyltransferase activity created_by: midori creation_date: 2012-05-31T16:42:14Z [Term] id: FYPO:0001089 name: increased glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001087 ! abnormal glucosyltransferase activity created_by: midori creation_date: 2012-05-31T16:42:35Z [Term] id: FYPO:0001090 name: resistance to heat shock during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to heat shock" EXACT [PomBase:mah] synonym: "resistance to heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistant to heat shock during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth is_a: FYPO:0002045 ! resistance to heat shock created_by: midori creation_date: 2012-06-01T13:48:51Z [Term] id: FYPO:0001091 name: normal cellular response to heat shock def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to heat shock is normal (i.e. indistinguishable from wild type). Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "normal cellular response to heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to heat shock during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-06-01T13:59:10Z [Term] id: FYPO:0001092 name: binding phenotype def: "A phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast binding phenotype" EXACT [PomBase:mah] is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2012-06-01T14:07:32Z [Term] id: FYPO:0001093 name: abolished chromatin binding def: "A molecular function phenotype in which chromatin binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "abolished chromatin association" EXACT [PomBase:vw] synonym: "chromatin binding abolished" EXACT [PomBase:mah] is_a: FYPO:0002576 ! abnormal chromatin binding created_by: midori creation_date: 2012-06-01T14:08:25Z [Term] id: FYPO:0001094 name: normal DNA replication origin binding def: "A molecular function phenotype in which occurrence of DNA binding at a replication origin by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal origin binding" EXACT [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2012-06-01T14:23:10Z [Term] id: FYPO:0001095 name: abolished DNA replication origin binding def: "A molecular function phenotype in which DNA binding at a replication origin by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished origin binding" EXACT [PomBase:mah] synonym: "DNA replication origin binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2012-06-01T14:24:32Z [Term] id: FYPO:0001096 name: normal RNA level during nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal cellular RNA level during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal mRNA level during nitrogen starvation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "normal RNA level during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal RNA level during nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal transcript level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2012-06-01T14:32:55Z [Term] id: FYPO:0001097 name: sensitive to amitrole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amitrole. Cells stop growing (and may die) at a concentration of amitrole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to amitrole" EXACT [PomBase:mah] synonym: "sensitive to 3-amino-1,2,4-triazole" EXACT [CHEBI:40036, PomBase:al] synonym: "sensitive to 3-aminotriazole" EXACT [] synonym: "sensitive to 3-AT" EXACT [] synonym: "sensitive to amitrole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to amitrole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-06-01T14:35:59Z [Term] id: FYPO:0001098 name: sensitive to 4-nitroquinoline N-oxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-nitroquinoline N-oxide. Cells stop growing (and may die) at a concentration of 4-nitroquinoline N-oxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 4-nitroquinoline N-oxide" EXACT [PomBase:mah] synonym: "sensitive to 4-nitroquinoline N-oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 4-nitroquinoline N-oxide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to 4-NQO" EXACT [PomBase:mah] synonym: "sensitive to 4NQO" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-06-01T14:37:39Z [Term] id: FYPO:0001099 name: normal growth on CCCP def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing carbonyl cyanide m-chlorophenyl hydrazone (CCCP)." [PomBase:mah] synonym: "normal cell population growth in presence of CCCP" EXACT [PomBase:mah] synonym: "normal cell population growth on carbonyl cyanide m-chlorophenyl hydrazone" EXACT [CHEBI:3259] synonym: "normal cell population growth on CCCP" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to CCCP" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on CCCP" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-01T14:38:51Z [Term] id: FYPO:0001100 name: normal growth on Gentian violet def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Gentian violet (also known as crystal violet)." [PomBase:mah] synonym: "normal cell population growth in presence of Gentian violet" EXACT [PomBase:mah] synonym: "normal cell population growth on crystal violet" EXACT [PomBase:mah] synonym: "normal cell population growth on Gentian violet" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride" EXACT [CHEBI:41688] synonym: "normal vegetative cell population growth on Gentian violet" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-01T14:39:48Z [Term] id: FYPO:0001101 name: decreased protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydrogen peroxide is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0001548 ! altered protein level during cellular response to hydrogen peroxide created_by: midori creation_date: 2012-06-01T14:47:37Z [Term] id: FYPO:0001102 name: increased protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydrogen peroxide is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0001548 ! altered protein level during cellular response to hydrogen peroxide created_by: midori creation_date: 2012-06-01T14:48:16Z [Term] id: FYPO:0001103 name: resistance to hydrogen peroxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hydrogen peroxide than normal." [PomBase:mah] synonym: "resistance to H2O2" EXACT [CHEBI:16240, PomBase:mah] synonym: "resistance to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-06-01T14:49:59Z [Term] id: FYPO:0001104 name: abnormal catalase activity def: "A molecular function phenotype in which the observed rate of catalase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-06-01T15:00:27Z [Term] id: FYPO:0001105 name: abolished catalase activity def: "A molecular function phenotype in which catalase activity is absent." [PomBase:mah] synonym: "catalase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001104 ! abnormal catalase activity created_by: midori creation_date: 2012-06-01T15:00:35Z [Term] id: FYPO:0001106 name: abnormal glutathione-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is abnormal." [PomBase:mah] synonym: "abnormal glutathione-disulphide reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-06-01T15:14:45Z [Term] id: FYPO:0001107 name: decreased glutathione-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is decreased." [PomBase:mah] synonym: "decreased glutathione-disulphide reductase activity" EXACT [PomBase:mah] synonym: "reduced glutathione-disulfide reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001106 ! abnormal glutathione-disulfide reductase activity created_by: midori creation_date: 2012-06-01T15:14:58Z [Term] id: FYPO:0001108 name: increased glutathione-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is increased." [PomBase:mah] synonym: "increased glutathione-disulphide reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001106 ! abnormal glutathione-disulfide reductase activity created_by: midori creation_date: 2012-06-01T15:15:04Z [Term] id: FYPO:0001109 name: resistance to menadione def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of menadione than normal." [PomBase:mah] synonym: "resistance to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to vitamin K3" RELATED [PomBase:al] synonym: "resistant to menadione" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-06-01T15:18:55Z [Term] id: FYPO:0001110 name: inviable after spore germination, multiple cell divisions, normal morphology def: "A phenotype in which a spore germinates to produce a cell of normal morphology (i.e. size, shape, and structure) that undergoes two or more rounds of cell division, and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, normal morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, normal morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, normal morphology" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2012-06-01T15:21:23Z [Term] id: FYPO:0001111 name: increased cellular glutathione disulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione disulfide (GSSG) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutathione disulfide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular glutathione disulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular glutathione disulphide level" EXACT [PomBase:mah] synonym: "increased cellular GSSG level" EXACT [CHEBI:17858, PomBase:al] synonym: "increased cellular oxidised glutathione level" EXACT [CHEBI:17858, PomBase:al] synonym: "increased glutathione disulfide accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-01T15:26:21Z [Term] id: FYPO:0001112 name: premature cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but begins earlier than normal." [PomBase:mah] synonym: "advanced cell cycle arrest in mitotic G1 phase during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "advanced cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "advanced cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "premature cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "premature mitotic cell cycle arrest in G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "premature mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "premature nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] is_a: FYPO:0000711 ! decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation created_by: midori creation_date: 2012-06-01T15:29:57Z [Term] id: FYPO:0001113 name: normal cellular response to pheromone def: "A cellular response phenotype in which the cellular response to a pheromone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000953 ! normal cellular response to chemical stimulus created_by: midori creation_date: 2012-06-01T15:37:34Z [Term] id: FYPO:0001114 name: normal cellular response to M-factor def: "A cellular response phenotype in which the cellular response to M-factor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001113 ! normal cellular response to pheromone created_by: midori creation_date: 2012-06-01T15:39:05Z [Term] id: FYPO:0001115 name: normal cellular response to P-factor def: "A cellular response phenotype in which the cellular response to P-factor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001113 ! normal cellular response to pheromone created_by: midori creation_date: 2012-06-01T15:39:33Z [Term] id: FYPO:0001116 name: decreased RNA level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to hydrogen peroxide" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to hydrogen peroxide" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-06-07T11:25:57Z [Term] id: FYPO:0001117 name: decreased RNA level during vegetative growth alt_id: FYPO:0002935 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased cellular mRNA level during vegetative growth" NARROW [PomBase:vw] synonym: "decreased cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased messenger RNA level during vegetative growth" NARROW [PomBase:mah] synonym: "decreased mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "decreased mRNA transcript level during vegetative growth" NARROW [PomBase:vw] synonym: "decreased RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "reduced mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "reduced RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2012-06-07T11:31:36Z [Term] id: FYPO:0001118 name: abnormal vegetative cell morphology def: "A cell phenotype in which cell morphology (i.e. the size, shape, or structure of the cell) is altered in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal cell morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vegetative cell morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-06-07T11:45:38Z [Term] id: FYPO:0001119 name: tapered vegetative cell def: "A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other in the vegetative growth phase of the life cycle. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that the difference between 'tapered cell' (FYPO:0000014) and 'spindle-shaped cell' (FYPO:0007230) is that a tapered cell is narrow at only one end, whereas a spindle-shaped cell is narrow at both ends. synonym: "bottle-shaped vegetative cell" EXACT [PomBase:vw] synonym: "bottle-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell morphology, bottle/skittle during vegetative growth" EXACT [PomBase:mah] synonym: "skittle-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "tapered cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000014 ! tapered cell is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2012-06-07T11:47:07Z [Term] id: FYPO:0001120 name: pear-shaped vegetative cell def: "A cell morphology phenotype in which a cell is shaped in the form of a pear in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PomBase:mah] synonym: "cell morphology, pear shaped during vegetative growth" EXACT [PomBase:mah] synonym: "ice cream cone-shaped cell during vegetative growth" EXACT [PMID:2236039, PomBase:vw] synonym: "pear-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "pear-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000020 ! pear-shaped cell is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2012-06-07T11:47:18Z [Term] id: FYPO:0001121 name: vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype in which cell shape is altered, but cell size remains normal, in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] synonym: "abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] synonym: "lumpy" RELATED [PomBase:vw] synonym: "vegetative cell, abnormal cell shape, normal cell length" NARROW [PomBase:mah] synonym: "vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001124 ! normal vegetative cell size is_a: FYPO:0002196 ! abnormal vegetative cell shape relationship: has_part FYPO:0001124 ! normal vegetative cell size relationship: has_part FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2012-06-07T11:56:50Z [Term] id: FYPO:0001122 name: elongated vegetative cell def: "A cell phenotype in which a cell is longer, and has a greater length:diameter ratio, than normal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Note that this term is classified as a type of abnormal cell shape, because wild-type cells are never seen with the proportions (length:diameter ratio) observed in elongated cells. Small cells, in contrast, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. synonym: "long vegetative cell" EXACT [PomBase:vw] is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0006634 ! increased vegetative cell length relationship: has_part FYPO:0006634 ! increased vegetative cell length created_by: midori creation_date: 2012-06-07T13:10:57Z [Term] id: FYPO:0001123 name: elongated spore def: "A cell phenotype in which a spore is longer than normal." [PomBase:mah] comment: Note that this term is classified as a type of abnormal cell shape, because wild-type cells are never seen with the proportions (length:diameter ratio) observed in elongated cells. Small cells, in contrast, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. synonym: "long spores" EXACT [PomBase:vw] is_a: FYPO:0002467 ! abnormal spore shape created_by: midori creation_date: 2012-06-07T13:11:48Z [Term] id: FYPO:0001124 name: normal vegetative cell size def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has normal volume and dimensions." [PomBase:mah] synonym: "normal cell size during vegetative growth" EXACT [PomBase:mah] synonym: "normal vegetative cell length" NARROW [PomBase:mah] synonym: "normal vegetative cell size during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-06-07T15:28:36Z [Term] id: FYPO:0001125 name: normal vegetative cell shape def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape." [PomBase:mah] synonym: "normal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "normal vegetative cell shape during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-06-07T15:28:36Z [Term] id: FYPO:0001126 name: abnormal cell shape def: "A cell morphology phenotype in which a cell has an abnormal shape." [PomBase:mah] synonym: "misshapen cell" RELATED [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2012-06-07T15:28:36Z [Term] id: FYPO:0001127 name: abnormal cell size def: "A cell morphology phenotype in which a cell has a volume or dimensions that differ from normal." [PomBase:mah] synonym: "abnormal cell length" NARROW [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2012-06-07T16:00:41Z [Term] id: FYPO:0001128 name: decreased septation index def: "A cell population phenotype in which the septation index is lower than normal. The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for wild type." [PomBase:mah] comment: A septation index of zero indicates cell cycle arrest. synonym: "decreased septation" RELATED [PomBase:mah] synonym: "reduced septation index" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-06-08T11:45:02Z [Term] id: FYPO:0001129 name: abnormal protein localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleus and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleus during vegetative growth" EXACT [GO:0034504, PomBase:mah] synonym: "abnormal protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0002956 ! abnormal protein localization to nucleus created_by: midori creation_date: 2012-06-08T12:02:23Z [Term] id: FYPO:0001130 name: increased protein localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus during vegetative growth" EXACT [GO:0034504, PomBase:mah] synonym: "increased protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth is_a: FYPO:0004456 ! increased protein localization to nucleus created_by: midori creation_date: 2012-06-08T12:04:38Z [Term] id: FYPO:0001131 name: abnormal protein localization to heterochromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004718 ! abnormal protein localization to heterochromatin created_by: midori creation_date: 2012-06-08T15:14:15Z [Term] id: FYPO:0001132 name: abolished protein localization to heterochromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to heterochromatin abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001131 ! abnormal protein localization to heterochromatin during vegetative growth created_by: midori creation_date: 2012-06-08T15:15:02Z [Term] id: FYPO:0001133 name: normal DNA replication def: "A cellular process phenotype in which DNA replication is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2012-06-08T15:41:39Z [Term] id: FYPO:0001134 name: normal mature 18S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 18S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 18S rRNA level" BROAD [PomBase:mah] synonym: "normal mature 18S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature 18S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature 18S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature 18S rRNA transcript level" EXACT [PomBase:mah] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2012-06-08T16:38:01Z [Term] id: FYPO:0001135 name: increased 35S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the 35S rRNA primary transcript measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 35S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased 35S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased 35S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased 35S rRNA precursor transcript level" EXACT [PomBase:vw] synonym: "increased 35S rRNA primary transcript level" EXACT [PomBase:mah, SO:0000325] is_a: FYPO:0003600 ! increased rRNA precursor level created_by: midori creation_date: 2012-06-08T16:40:54Z [Term] id: FYPO:0001136 name: increased 27S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 27S rRNA precursor measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 27S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased 27S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased 27S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased 27S rRNA precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0003600 ! increased rRNA precursor level created_by: midori creation_date: 2012-06-08T16:44:25Z [Term] id: FYPO:0001137 name: decreased mature 25S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 25S rRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 25S rRNA level" BROAD [PomBase:mah] synonym: "decreased mature 25S rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature 25S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature 25S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature 25S rRNA transcript level" EXACT [PomBase:vw] synonym: "reduced mature 25S rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005996 ! altered rRNA or precursor level created_by: midori creation_date: 2012-06-08T16:45:47Z [Term] id: FYPO:0001138 name: decreased mature 5.8S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 5.8S rRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 5.8S rRNA level" BROAD [PomBase:mah] synonym: "decreased 5.8S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature 5.8S rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature 5.8S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature 5.8S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature 5.8S rRNA transcript level" EXACT [PomBase:vw] synonym: "reduced mature 5.8S rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005996 ! altered rRNA or precursor level created_by: midori creation_date: 2012-06-08T16:47:19Z [Term] id: FYPO:0001139 name: abnormal leucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-leucine import" EXACT [PomBase:mah] synonym: "abnormal L-leucine import across plasma membrane" EXACT [GO:1903801] synonym: "abnormal leucine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal leucine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal leucine import into cell" EXACT [PomBase:al] synonym: "abnormal leucine uptake" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-06-11T14:24:42Z [Term] id: FYPO:0001140 name: decreased leucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-leucine import" EXACT [PomBase:mah] synonym: "decreased L-leucine import across plasma membrane" EXACT [GO:1903801] synonym: "decreased leucine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased leucine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased leucine import into cell" EXACT [PomBase:al] synonym: "decreased leucine uptake" EXACT [PomBase:mah] synonym: "reduced leucine import" EXACT [PomBase:mah] is_a: FYPO:0001139 ! abnormal leucine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-06-11T14:26:26Z [Term] id: FYPO:0001141 name: abolished transcriptional response to pheromone def: "A conjugation phenotype in which regulation of transcription in response to mating pheromone is abolished." [PomBase:mah] synonym: "abolished regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0046019, PomBase:mah] synonym: "transcriptional response to pheromone abolished" EXACT [PomBase:mah] is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2012-06-11T14:48:00Z [Term] id: FYPO:0001142 name: normal Man8GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is normal (i.e. indistinguishable from wild type). Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:64048, CHEBI:64052, PMID:12686557, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "normal cellular Man8GlcNAc level" EXACT [PomBase:al] synonym: "normal Man8GlcNAc accumulation" RELATED [PomBase:mah] synonym: "normal Man8GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal Man8GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "normal Man8GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-06-14T15:52:46Z [Term] id: FYPO:0001143 name: normal Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man9GlcNAc2 measured in a cell is normal (i.e. indistinguishable from wild type). Man9GlcNAc2 is any N-glycan that consists of a branched undecasaccharide consisting of nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59579, PMID:12686557, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "normal cellular Man9GlcNAc level" EXACT [PomBase:al] synonym: "normal Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "normal Man9GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "normal Man9GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-06-14T15:55:35Z [Term] id: FYPO:0001144 name: decreased Man8GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is lower than normal. Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:64048, CHEBI:64052, PMID:12686557, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "decreased cellular Man8GlcNAc level" EXACT [PomBase:al] synonym: "decreased Man8GlcNAc accumulation" RELATED [PomBase:mah] synonym: "decreased Man8GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Man8GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Man8GlcNAc2 level" EXACT [PomBase:mah] synonym: "reduced Man8GlcNAc level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-06-14T15:59:43Z [Term] id: FYPO:0001145 name: increased Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man9GlcNAc2 measured in a cell is higher than normal. Man9GlcNAc2 is any N-glycan that consists of a branched undecasaccharide consisting of nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59579, PMID:12686557, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "increased cellular Man9GlcNAc level" EXACT [PomBase:al] synonym: "increased Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "increased Man9GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "increased Man9GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-06-14T16:00:30Z [Term] id: FYPO:0001146 name: decreased misfolded glycoprotein degradation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of misfolded glycoprotein degradation is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased misfolded glycoprotein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased misfolded glycoprotein catabolism during vegetative growth" EXACT [PomBase:mah] synonym: "decreased misfolded glycoprotein degradation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced misfolded glycoprotein degradation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth created_by: midori creation_date: 2012-06-14T16:04:32Z [Term] id: FYPO:0001147 name: normal mating efficiency def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is normal (i.e. the same as in wild-type cells)." [PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-06-14T16:21:22Z [Term] id: FYPO:0001148 name: normal growth on amiloride def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amiloride." [PomBase:mah] synonym: "normal cell population growth in presence of amiloride" EXACT [PomBase:mah] synonym: "normal cell population growth on amiloride" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to amiloride" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on amiloride" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-14T16:30:50Z [Term] id: FYPO:0001149 name: normal growth on methylamine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methylamine." [PomBase:mah] synonym: "normal cell population growth in presence of methylamine" EXACT [PomBase:mah] synonym: "normal cell population growth on methylamine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to methylamine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on methylamine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-14T16:33:06Z [Term] id: FYPO:0001150 name: sensitive to methylamine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methylamine. Cells stop growing (and may die) at a concentration of methylamine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to methylamine" EXACT [PomBase:mah] synonym: "sensitive to methylamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to methylamine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-06-14T16:34:29Z [Term] id: FYPO:0001151 name: cell cycle arrest at mitotic G2/M phase transition during starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition when the cell is subject to starvation for one or more nutrients." [PMID:19366728, PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition during depletion" EXACT [PomBase:vw] synonym: "cell cycle arrest at mitotic G2/M phase transition during deprivation" EXACT [PomBase:vw] synonym: "cell cycle arrest in mitotic G2 phase during starvation" RELATED [PomBase:mah] synonym: "mitotic cell cycle arrest at mitotic G2/M phase transition during starvation" EXACT [PomBase:mah] synonym: "mitotic G2 phase arrest during starvation" EXACT [PomBase:mah] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition created_by: midori creation_date: 2012-06-14T16:45:50Z [Term] id: FYPO:0001152 name: decreased RNA level during nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to nitrogen starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased transcript level during nitrogen starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation created_by: midori creation_date: 2012-06-14T16:52:51Z [Term] id: FYPO:0001153 name: normal cellular methylamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of methylamine measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular methylamine accumulation" RELATED [PomBase:mah] synonym: "normal cellular methylamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular methylamine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-14T16:54:23Z [Term] id: FYPO:0001154 name: increased cellular methylamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of methylamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular methylamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular methylamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased methylamine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-14T16:55:28Z [Term] id: FYPO:0001155 name: altered effect on growth medium def: "A phenotype in which the changes that take place in growth medium, due to metabolism, secretion, etc. by a cell or population of cells, differs from normal." [PomBase:mah] synonym: "abnormal effect on growth medium" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-06-15T12:57:29Z [Term] id: FYPO:0001156 name: decreased pH of growth medium def: "A phenotype in which cells cause the pH of their growth medium to decrease by a greater amount than normal." [PomBase:mah] synonym: "decreased pH level of growth medium" EXACT [PomBase:al] synonym: "increased growth medium acidification" EXACT [PMID:10467002, PomBase:mah] synonym: "reduced pH of growth medium" EXACT [PomBase:mah] is_a: FYPO:0001155 ! altered effect on growth medium created_by: midori creation_date: 2012-06-15T13:37:06Z [Term] id: FYPO:0001157 name: increased cell population growth rate at high pH def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium with higher than standard pH. Standard S. pombe growth media are approximately pH 5.6." [PMID:10467002, PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced growth at high pH" RELATED [PomBase:mah] synonym: "fast cell population growth at high pH" EXACT [PomBase:mah] synonym: "increased cell population growth rate at high pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell population growth rate at high pH during vegetative growth" EXACT [PomBase:mah] synonym: "increased cell population proliferation at high pH" RELATED [PomBase:vw] synonym: "increased cell proliferation at high pH" RELATED [PomBase:vw] is_a: FYPO:0000636 ! increased cell population growth rate created_by: midori creation_date: 2012-06-15T13:43:25Z [Term] id: FYPO:0001158 name: normal cellular pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular pH during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular pH level" EXACT [PomBase:al] is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-06-15T13:47:22Z [Term] id: FYPO:0001159 name: increased cellular pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is higher than normal." [PomBase:mah] synonym: "increased cellular pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular pH during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular pH level" EXACT [PomBase:al] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2012-06-15T13:47:43Z [Term] id: FYPO:0001160 name: cell cycle arrest at mitotic G2/M phase transition during stationary phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition when the population in which the cell is found is in stationary phase." [PMID:19366728, PomBase:mah] synonym: "cell cycle arrest in mitotic G2 phase during stationary phase" RELATED [PomBase:mah] synonym: "mitotic cell cycle arrest at mitotic G2/M phase transition during stationary phase" EXACT [PomBase:mah] synonym: "mitotic G2 phase arrest during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition created_by: midori creation_date: 2012-06-15T14:04:54Z [Term] id: FYPO:0001162 name: decreased cell population growth on raffinose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under aerobic conditions and in a medium containing raffinose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased aerobic cell growth on raffinose carbon source" NARROW [PomBase:mah] synonym: "decreased growth on raffinose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on raffinose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on raffinose carbon source" EXACT [PomBase:mah] synonym: "slow aerobic cell growth on raffinose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-06-15T14:21:23Z [Term] id: FYPO:0001164 name: normal growth on glucose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glucose as the carbon source." [PomBase:mah] synonym: "normal cell population growth on glucose carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on dextrose carbon source" EXACT [PomBase:al] synonym: "normal vegetative cell population growth on glucose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-15T14:22:57Z [Term] id: FYPO:0001165 name: inviable cell following anaerobic growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell that is exposed to anaerobic conditions fails to grow upon being returned to aerobic conditions, and eventually dies." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable following anaerobic vegetative growth" EXACT [PomBase:mah] synonym: "lethal; cell following anaerobic growth" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-06-15T14:28:05Z [Term] id: FYPO:0001166 name: normal growth on fructose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing fructose as the carbon source." [PomBase:mah] synonym: "normal cell population growth on fructose carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on fructose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-18T14:58:12Z [Term] id: FYPO:0001167 name: abnormal ATPase activity def: "A molecular function phenotype in which the observed rate of ATPase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-06-18T15:16:22Z [Term] id: FYPO:0001168 name: decreased ATPase activity def: "A molecular function phenotype in which the observed rate of ATPase activity is decreased." [PomBase:mah] synonym: "reduced ATPase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001167 ! abnormal ATPase activity created_by: midori creation_date: 2012-06-18T15:16:30Z [Term] id: FYPO:0001169 name: normal proton transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which proton (H+) transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal hydrogen ion transport" EXACT [PomBase:mah] synonym: "normal proton transmembrane transport" EXACT [GO:1902600] synonym: "normal proton transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal proton transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-06-18T15:18:27Z [Term] id: FYPO:0001170 name: decreased methionine import during nitrogen starvation def: "A cellular process phenotype in which the import of methionine into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "decreased L-methionine import across plasma membrane during nitrogen starvation" EXACT [GO:1905544] synonym: "decreased L-methionine import during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased methionine import during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased methionine import during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased methionine import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased methionine transport into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased methionine uptake during nitrogen starvation" EXACT [PomBase:mah] synonym: "reduced methionine import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001558 ! decreased methionine import is_a: FYPO:0001648 ! abnormal amino acid import during nitrogen starvation created_by: midori creation_date: 2012-06-18T15:29:46Z [Term] id: FYPO:0001171 name: decreased cellular pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is lower than normal." [PomBase:mah] synonym: "decreased cellular pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular pH during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular pH level" EXACT [PomBase:al] synonym: "reduced cellular pH" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2012-06-18T15:37:06Z [Term] id: FYPO:0001172 name: abnormal 7-methylguanosine cap hypermethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to form a 2,2,7-trimethylguanosine cap structure is abnormal." [PomBase:mah] synonym: "abnormal 2,2,7-trimethylguanosine cap formation" EXACT [GO:0036261, PomBase:mah] synonym: "abnormal 7-methylguanosine cap hypermethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal 7-methylguanosine cap hypermethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal conversion of m(7)G to m(3)G" EXACT [GO:0036261, PomBase:mah] synonym: "abnormal snoRNA capping" NARROW [GO:0036261, PomBase:mah] synonym: "abnormal snRNA capping" NARROW [GO:0036261, PomBase:mah] synonym: "abnormal TMG cap formation" EXACT [GO:0036261, PomBase:mah] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2012-06-18T15:51:40Z [Term] id: FYPO:0001173 name: abolished 7-methylguanosine cap hypermethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to form a 2,2,7-trimethylguanosine cap structure is abolished." [GO:0036261, PomBase:mah] synonym: "2,2,7-trimethylguanosine cap formation abolished" EXACT [GO:0036261, PomBase:mah] synonym: "7-methylguanosine cap hypermethylation abolished" EXACT [PomBase:mah] synonym: "7-methylguanosine cap hypermethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "abolished 7-methylguanosine cap hypermethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "conversion of m(7)G to m(3)G abolished" EXACT [GO:0036261, PomBase:mah] synonym: "snoRNA capping abolished" NARROW [GO:0036261, PomBase:mah] synonym: "snRNA capping abolished" NARROW [GO:0036261, PomBase:mah] synonym: "TMG cap formation abolished" EXACT [GO:0036261, PomBase:mah] is_a: FYPO:0000371 ! abolished RNA modification is_a: FYPO:0001172 ! abnormal 7-methylguanosine cap hypermethylation created_by: midori creation_date: 2012-06-18T15:57:19Z [Term] id: FYPO:0001174 name: normal growth on sucrose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing sucrose as the carbon source." [PomBase:mah] synonym: "normal cell population growth on sucrose carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on sucrose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-21T11:11:55Z [Term] id: FYPO:0001175 name: normal growth on maltose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing maltose as the carbon source." [PomBase:mah] synonym: "normal cell population growth on maltose carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on maltose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-21T11:12:36Z [Term] id: FYPO:0001176 name: decreased cell population growth on sucrose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing sucrose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on sucrose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on sucrose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on sucrose carbon source" RELATED [PomBase:mah] synonym: "slow cell growth on sucrose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-06-21T11:13:07Z [Term] id: FYPO:0001177 name: decreased cell population growth on trehalose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing trehalose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on trehalose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on trehalose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on trehalose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on trehalose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-06-21T11:13:29Z [Term] id: FYPO:0001178 name: loss of viability upon nitrogen starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells in a culture in stationary phase are deprived of nitrogen." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under nitrogen-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. Also consider 'sensitive to nitrogen starvation' (FYPO:0002124). synonym: "decreased viability upon nitrogen starvation" EXACT [PomBase:mah] synonym: "loss of cell population viability upon nitrogen starvation" EXACT [PomBase:mah] synonym: "loss of viability in stationary phase upon nitrogen depletion" RELATED [PomBase:mah] synonym: "loss of viability upon nitrogen depletion" EXACT [PomBase:al] synonym: "loss of viability upon nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced viability upon nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000244 ! loss of viability upon nutrient depletion created_by: midori creation_date: 2012-06-27T14:04:23Z [Term] id: FYPO:0001179 name: abolished protein localization during vegetative growth def: "A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found in the vegetative growth phase of the life cycle." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abolished protein localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from specific location in cell during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001375 ! abolished protein localization created_by: midori creation_date: 2012-06-27T15:07:09Z [Term] id: FYPO:0001180 name: obsolete increased protein tyrosine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-tyrosine phosphorylation during vegetative growth" EXACT [GO:0018108, PomBase:mah] synonym: "increased protein tyrosine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased tyrosine phosphorylation during vegetative growth" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0001038 created_by: midori creation_date: 2012-06-27T15:32:08Z [Term] id: FYPO:0001181 name: normal maltase activity def: "A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal maltose alpha-glucosidase activity" EXACT [GO:0032450, PomBase:mah] is_a: FYPO:0001182 ! normal alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:33:02Z [Term] id: FYPO:0001182 name: normal alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-07-05T13:33:56Z [Term] id: FYPO:0001183 name: abnormal alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-07-05T13:36:08Z [Term] id: FYPO:0001184 name: abnormal maltase activity def: "A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is abnormal." [PomBase:mah] synonym: "abnormal maltose alpha-glucosidase activity" EXACT [GO:0032450, PomBase:mah] is_a: FYPO:0001183 ! abnormal alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:36:57Z [Term] id: FYPO:0001185 name: decreased alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is decreased." [PomBase:mah] synonym: "reduced alpha-glucosidase activity" EXACT [PomBase:mah] is_a: FYPO:0001183 ! abnormal alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:38:13Z [Term] id: FYPO:0001186 name: decreased maltase activity def: "A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is decreased." [PomBase:mah] synonym: "decreased maltose alpha-glucosidase activity" EXACT [GO:0032450, PomBase:mah] synonym: "reduced maltase activity" EXACT [PomBase:mah] synonym: "reduced maltose alpha-glucosidase activity" RELATED [GO:0032450, PomBase:mah] is_a: FYPO:0001184 ! abnormal maltase activity is_a: FYPO:0001185 ! decreased alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:38:33Z [Term] id: FYPO:0001187 name: decreased cell density in stationary phase def: "A cell population phenotype in which a population reaches stationary phase at, and maintains, a lower cell density than wild type." [PomBase:mah] synonym: "reduced cell density in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-07-05T14:04:36Z [Term] id: FYPO:0001188 name: sensitive to Calcofluor White def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Calcofluor White. Cells stop growing (and may die) at a concentration of Calcofluor White that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Calcofluor White" EXACT [PomBase:mah] synonym: "sensitive to Calcofluor White during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to Calcofluor White during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-07-05T14:32:40Z [Term] id: FYPO:0001189 name: sensitive to cilofungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cilofungin. Cells stop growing (and may die) at a concentration of cilofungin that allows wild type cells to grow." [PomBase:mah] comment: Cilofungin is an echinocandin antibiotic, related to echinocandin B. synonym: "hypersensitive to cilofungin" EXACT [PomBase:mah] synonym: "sensitive to cilofungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cilofungin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-07-05T14:34:21Z [Term] id: FYPO:0001190 name: sensitive to cell wall-degrading enzymes alt_id: FYPO:0001191 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more enzymes that degrades cell wall polysaccharides. Cells stop growing (and may die) at a concentration of such enzymes that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cell wall-degrading enzymes" EXACT [PomBase:mah] synonym: "sensitive to beta-1,3-glucan laminaripentaohydrolase" NARROW [PomBase:al, PomBase:mah] synonym: "sensitive to cell wall-degrading enzymes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cell wall-degrading enzymes during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to lysing enzymes from Trichoderma harzianum" NARROW [PomBase:al] synonym: "sensitive to Lyticase" NARROW [PomBase:mah] synonym: "sensitive to Novozyme 234" NARROW [PomBase:mah] synonym: "sensitive to Zymolyase" NARROW [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-07-05T14:41:18Z [Term] id: FYPO:0001192 name: normal growth on cell wall-degrading enzymes alt_id: FYPO:0001193 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which vegetative cell growth is normal (i.e. indistinguishable from wild type) in a medium containing one or more enzymes that degrades cell wall polysaccharides." [PomBase:mah] synonym: "normal cell population growth in presence of cell wall-degrading enzymes" EXACT [PomBase:mah] synonym: "normal cell population growth on beta-1,3-glucan laminaripentaohydrolase" NARROW [PomBase:al, PomBase:mah] synonym: "normal cell population growth on cell wall-degrading enzymes" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on lysing enzymes from Trichoderma harzianum" NARROW [PomBase:al] synonym: "normal cell population growth on Lyticase" NARROW [PomBase:mah] synonym: "normal cell population growth on Novozyme 234" NARROW [PomBase:mah] synonym: "normal cell population growth on Zymolyase" NARROW [PomBase:mah] synonym: "normal cellular response to cell wall-degrading enzymes" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cell wall-degrading enzymes" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-05T15:35:28Z [Term] id: FYPO:0001194 name: increased beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell is greater than normal." [PomBase:mah] synonym: "increased beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "increased beta-glucan accumulation" RELATED [PomBase:mah] synonym: "increased beta-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular beta-glucan level" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-07-05T15:53:01Z [Term] id: FYPO:0001195 name: decreased galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular galactomannan level" EXACT [PomBase:mah] synonym: "decreased galactomannan accumulation" RELATED [PomBase:mah] synonym: "decreased galactomannan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased galactomannan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced galactomannan level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-07-05T15:54:27Z [Term] id: FYPO:0001196 name: normal alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "normal alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "normal alpha-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal alpha-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular alpha-glucan level" EXACT [PomBase:al] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-07-05T15:55:45Z [Term] id: FYPO:0001197 name: decreased cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased calcium accumulation" RELATED [PomBase:al] synonym: "decreased cellular calcium ion level" EXACT [PomBase:mah] synonym: "decreased cellular calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular calcium level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular calcium level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-07-05T16:12:05Z [Term] id: FYPO:0001198 name: increased cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is higher than normal." [PomBase:mah] synonym: "increased calcium accumulation" RELATED [PomBase:mah] synonym: "increased cellular calcium ion level" EXACT [PomBase:mah] synonym: "increased cellular calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular calcium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-07-05T16:13:54Z [Term] id: FYPO:0001199 name: normal cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular calcium accumulation" RELATED [PomBase:mah] synonym: "normal cellular calcium ion level" EXACT [PomBase:mah] synonym: "normal cellular calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular calcium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-05T16:14:49Z [Term] id: FYPO:0001200 name: abnormal cellular response to calcium starvation def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to calcium starvation is abnormal." [PomBase:mah] comment: Use this term if you have assayed the response to calcium starvation at the subcellular or molecular level. If you have assayed growth of cells exposed to calcium starvation in culture, use 'sensitive to calcium starvation' (FYPO:0001201). synonym: "abnormal cellular response to calcium depletion" EXACT [PomBase:vw] synonym: "abnormal cellular response to calcium deprivation" EXACT [PomBase:vw] synonym: "abnormal cellular response to calcium ion starvation" EXACT [GO:0072732, PomBase:mah] synonym: "abnormal cellular response to calcium starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to calcium starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001339 ! abnormal cellular response to starvation during vegetative growth created_by: midori creation_date: 2012-07-05T16:38:24Z [Term] id: FYPO:0001201 name: sensitive to calcium ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium ion starvation." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to calcium starvation in culture. If you have assayed the response to calcium starvation at the subcellular or molecular level, consider annotating to 'abnormal cellular response to calcium starvation' (FYPO:0001200). synonym: "decreased growth during cellular response to calcium ion starvation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to calcium ion starvation" EXACT [PomBase:mah] synonym: "hypersensitive to calcium ion starvation" EXACT [PomBase:mah] synonym: "reduced growth in low calcium" RELATED [PomBase:vw] synonym: "sensitive to calcium ion depletion" EXACT [PomBase:vw] synonym: "sensitive to calcium ion deprivation" EXACT [PomBase:vw] synonym: "sensitive to calcium ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to calcium ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to calcium starvation" EXACT [GO:0072732, PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2012-07-05T16:43:08Z [Term] id: FYPO:0001202 name: normal cellular response to calcium starvation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to calcium starvation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to calcium depletion" EXACT [PomBase:vw] synonym: "normal cellular response to calcium deprivation" EXACT [PomBase:vw] synonym: "normal cellular response to calcium ion starvation" EXACT [GO:0072732, PomBase:mah] synonym: "normal cellular response to calcium starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to calcium starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-07-05T16:45:20Z [Term] id: FYPO:0001203 name: coflocculating cells def: "A cell population phenotype that reflects increased occurrence of coflocculation. In coflocculation, yeast cells coaggregate with cells of another species, usually bacteria." [PMID:11472912, PomBase:mah] comment: Note: coflocculation between S. pombe and E. coli is sensitive to mannose but not to glucose or galactose. Plant lectins such as HHA, GNA, NPA, or Concanavalin A (ConA) decrease but do not abolish S. pombe-E. coli coflocculation. Cations have different effects: Li+, Na+, K+, Mg2+ or Mn2+ increase coflocculation, Co2+, Zn2+, and Ca2+ have no effect, and Cu2+ or Hg2+ completely abolish coflocculation. synonym: "co-flocculating cells" EXACT [PomBase:mah] synonym: "increased coflocculation" EXACT [PomBase:mah] is_a: FYPO:0000155 ! increased flocculation created_by: midori creation_date: 2012-07-06T15:40:35Z [Term] id: FYPO:0001204 name: mistimed mitosis def: "A cellular process phenotype in which cells enter mitosis earlier or later than normal, relative to cell size or DNA integrity checkpoint status." [PomBase:mah] synonym: "abnormal onset of mitosis" EXACT [PomBase:mah] synonym: "mistimed mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mistimed mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2012-07-06T16:15:36Z [Term] id: FYPO:0001205 name: abolished alpha-glucosidase activity def: "A molecular function phenotype in which alpha-glucosidase activity is absent." [PomBase:mah] synonym: "alpha-glucosidase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity created_by: midori creation_date: 2012-07-09T17:10:25Z [Term] id: FYPO:0001206 name: abolished maltase activity def: "A molecular function phenotype in which maltase activity is absent." [PomBase:mah] synonym: "maltase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0001184 ! abnormal maltase activity is_a: FYPO:0001205 ! abolished alpha-glucosidase activity created_by: midori creation_date: 2012-07-09T17:13:55Z [Term] id: FYPO:0001207 name: sensitive to raffinose def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to raffinose. Cells stop growing (and may die) at a concentration of raffinose that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to raffinose" EXACT [PomBase:mah] synonym: "sensitive to raffinose during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to raffinose during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-07-12T10:30:03Z [Term] id: FYPO:0001208 name: substance absent from cell during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in a cell is too low to detect." [PomBase:mah] synonym: "substance absent from cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2012-07-12T12:09:35Z [Term] id: FYPO:0001209 name: polysaccharide absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is too low to detect." [PomBase:mah] synonym: "polysaccharide absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "polysaccharide absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level during vegetative growth is_a: FYPO:0001208 ! substance absent from cell during vegetative growth created_by: midori creation_date: 2012-07-12T12:12:20Z [Term] id: FYPO:0001210 name: Glc2Man9GlcNAc absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc2Man9GlcNAc2 measured in a cell is too low to detect. Glc2Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing two D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59082, PMID:9813085, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "absent Glc2Man9GlcNAc" EXACT [PomBase:al] synonym: "Glc2Man9GlcNAc absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "Glc2Man9GlcNAc absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "Glc2Man9GlcNAc2 absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001209 ! polysaccharide absent from cell created_by: midori creation_date: 2012-07-12T12:13:39Z [Term] id: FYPO:0001211 name: Glc3Man9GlcNAc absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc3Man9GlcNAc measured in a cell is too low to detect. Glc3Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing three D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:53019, PMID:9813085, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "absent Glc3Man9GlcNAc" EXACT [PomBase:al] synonym: "G3M9 glycan absent from cell" EXACT [PMID:30389790] synonym: "Glc3Man9GlcNAc absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "Glc3Man9GlcNAc absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "Glc3Man9GlcNAc2 absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001209 ! polysaccharide absent from cell is_a: FYPO:0001289 ! decreased phospholipid level created_by: midori creation_date: 2012-07-12T12:15:33Z [Term] id: FYPO:0001212 name: decreased Glc1Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc1Man9GlcNAc2 measured in a cell is lower than normal. Glc1Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing one D-glucose residue, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59080, PMID:9813085, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "decreased cellular Glc1Man9GlcNAc level" EXACT [PomBase:al] synonym: "decreased Glc1Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "decreased Glc1Man9GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Glc1Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Glc1Man9GlcNAc2 level" EXACT [PomBase:mah] synonym: "reduced Glc1Man9GlcNAc level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-07-12T12:16:24Z [Term] id: FYPO:0001213 name: increased Man8GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is higher than normal. Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:64048, CHEBI:64052, PMID:9813085, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "increased cellular Man8GlcNAc level" EXACT [PomBase:al] synonym: "increased Man8GlcNAc accumulation" RELATED [PomBase:mah] synonym: "increased Man8GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased Man8GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "increased Man8GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2012-07-12T12:17:32Z [Term] id: FYPO:0001214 name: sensitive to potassium chloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium chloride. Cells stop growing (and may die) at a concentration of potassium chloride that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to potassium chloride" EXACT [PomBase:mah] synonym: "sensitive to KCl" EXACT [PomBase:mah] synonym: "sensitive to potassium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to potassium chloride during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-07-12T14:21:19Z [Term] id: FYPO:0001215 name: normal protein complex assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of a protein complex at the cellular level is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular protein complex assembly during vegetative growth" EXACT [GO:0034622] synonym: "normal protein complex assembly during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0006839 ! normal protein-containing complex assembly created_by: midori creation_date: 2012-07-12T14:30:00Z [Term] id: FYPO:0001216 name: normal SAGA complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of a SAGA complex onto chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal SAGA complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal SAGA complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2012-07-12T14:32:23Z [Term] id: FYPO:0001217 name: abnormal nuclear import def: "A cellular process phenotype in which nuclear import is abnormal. Nuclear import is the directed movement of any substance out of the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abnormal nuclear import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000518 ! abnormal nuclear transport during vegetative growth created_by: midori creation_date: 2012-07-12T14:39:54Z [Term] id: FYPO:0001218 name: abolished nuclear export during cellular response to nitrogen starvation def: "A cellular process phenotype in which nuclear export does not occur when the cell is subject to nitrogen starvation. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abolished nuclear export during cellular response to nitrogen depletion" EXACT [PomBase:vw] synonym: "abolished nuclear export during cellular response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "abolished nuclear export during cellular response to nitrogen starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent nuclear export during response to nitrogen starvation" EXACT [PomBase:mah] synonym: "nuclear export during response to nitrogen starvation abolished" EXACT [PomBase:mah] synonym: "nuclear export during response to nitrogen starvation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export in response to nitrogen starvation abolished" EXACT [PomBase:al] is_a: FYPO:0000507 ! abolished nuclear export created_by: midori creation_date: 2012-07-12T14:41:50Z [Term] id: FYPO:0001219 name: increased protein level during cellular response to nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to nitrogen starvation is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to nitrogen starvation" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to nitrogen depletion" EXACT [PomBase:vw] synonym: "increased protein level during cellular response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "increased protein level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000836 ! increased protein level is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation created_by: midori creation_date: 2012-07-12T15:10:12Z [Term] id: FYPO:0001220 name: increased protein level during cellular response to pheromone def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to a pheromone is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to pheromone" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to pheromone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to pheromone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000836 ! increased protein level created_by: midori creation_date: 2012-07-12T15:13:41Z [Term] id: FYPO:0001221 name: normal nucleus:cytoplasm ratio def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is in the same range as wild type (approximately 0.076-0.089)." [PMID:17998401, PomBase:mah] synonym: "normal nuclear:cytoplasmic ratio" EXACT [PomBase:mah] synonym: "normal nuclear:cytoplasmic volume ratio" EXACT [PomBase:mah] synonym: "normal nucleus:cell volume ratio" EXACT [PomBase:mah] synonym: "normal nucleus:cytoplasm ratio during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleus:cytoplasm ratio during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleus:cytoplasm volume ratio" EXACT [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-07-12T15:15:47Z [Term] id: FYPO:0001222 name: binucleate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains two nuclei." [PomBase:mah] comment: When using this term, also consider annotating to a cell cycle arrest term, such as 'abnormal cell cycle arrest in mitotic telophase' (FYPO:0000622); 'abnormal cell cycle arrest in mitotic anaphase' (FYPO:0000619) may be applicable if the assay detects DNA masses. Binucleate cells often arise as a result of cell cycle arrest. synonym: "binucleate cells during vegetative growth" EXACT [PomBase:al] synonym: "binucleate during vegetative growth" EXACT [PomBase:mah] synonym: "binucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell created_by: midori creation_date: 2012-07-12T15:37:08Z [Term] id: FYPO:0001223 name: binucleate multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and more than one septum." [PomBase:mah] synonym: "binucleate multiseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "binucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001222 ! binucleate vegetative cell is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell relationship: has_part FYPO:0001222 ! binucleate vegetative cell created_by: midori creation_date: 2012-07-12T15:39:43Z [Term] id: FYPO:0001224 name: obsolete binucleate monoseptate cell def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum." [PomBase:mah] synonym: "binucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-07-12T15:40:42Z [Term] id: FYPO:0001225 name: monoseptate def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single septum." [PomBase:mah] synonym: "monoseptate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "monoseptate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2012-07-12T15:42:41Z [Term] id: FYPO:0001226 name: inviable mononucleate vegetative cell with mislocalized septum and anucleate compartment def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and contains a single nucleus and an asymmetrically located septum. The septum divides the cell into two compartments, one of which contains the nucleus." [PomBase:mah] synonym: "inviable mononucleate cell with mislocalized septum during vegetative growth" EXACT [PomBase:mah] synonym: "inviable mononucleate monoseptate vegetative cell with mislocalized septum" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with abnormal septum location" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with abnormal septum position" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with asymmetric septum" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with asymmetrically located septum" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with mislocalised septum" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with mislocalized septum" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell with mislocalized septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable mononucleate vegetative cell with misplaced septum" EXACT [PomBase:vw] synonym: "inviable mononucleate vegetative cell with single mislocalized septum" EXACT [PomBase:mah] synonym: "lethal; mononucleate vegetative cell with mislocalized septum" EXACT [PomBase:mah] is_a: FYPO:0002303 ! inviable mononucleate monoseptate vegetative cell with anucleate compartment is_a: FYPO:0007652 ! mononucleate vegetative cell with mislocalized septum and anucleate compartment relationship: has_part FYPO:0000339 ! mislocalized septum during vegetative growth created_by: midori creation_date: 2012-07-12T15:44:34Z [Term] id: FYPO:0001227 name: protein mislocalized to cytoplasm during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there, during a cellular response to hydrogen peroxide." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the cytoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to cytoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:vw] synonym: "protein mislocalised to cytoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during cellular response to H2O2" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to cytoplasm during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm in response to hydrogen peroxide" EXACT [PomBase:al] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2012-07-13T16:15:07Z [Term] id: FYPO:0001228 name: increased nuclear protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in vegetative growth phase of the life cycle, in which the amount of protein measured in the cell nucleus is higher than normal during a cellular response to hydrogen peroxide. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased nuclear protein level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "increased nuclear protein level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nuclear protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level in nucleus during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "nuclear accumulation of protein during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "nuclear protein accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "nuclear protein accumulation during cellular response to hydrogen peroxide during vegetative growth" RELATED [PomBase:mah] synonym: "nuclear protein accumulation in response to hydrogen peroxide" RELATED [PomBase:al] is_a: FYPO:0000255 ! increased nuclear protein level during vegetative growth is_a: FYPO:0001102 ! increased protein level during cellular response to hydrogen peroxide created_by: midori creation_date: 2012-07-13T16:39:13Z [Term] id: FYPO:0001229 name: abnormal cell cortex morphology def: "A physical cellular phenotype in which the size, shape, or structure of all or part of the cell cortex is abnormal. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2012-07-16T13:51:27Z [Term] id: FYPO:0001230 name: abnormal cell cortex morphology during nitrogen starvation def: "A physical cellular phenotype in which the size, shape, or structure of all or part of the cell cortex is abnormal when the cell is subject to nitrogen starvation. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal cell cortex morphology during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal cell cortex morphology during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0001229 ! abnormal cell cortex morphology created_by: midori creation_date: 2012-07-16T13:52:15Z [Term] id: FYPO:0001231 name: normal cell cortex morphology def: "A physical cellular phenotype in which the size, shape, and structure of the cell cortex is normal (i.e. indistinguishable from wild type). The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2012-07-16T13:54:21Z [Term] id: FYPO:0001232 name: normal cell cortex morphology during nitrogen starvation def: "A physical cellular phenotype in which the size, shape, and structure of the cell cortex are normal when the cell is subject to nitrogen starvation. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "normal cell cortex morphology during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal cell cortex morphology during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0001231 ! normal cell cortex morphology created_by: midori creation_date: 2012-07-16T13:56:11Z [Term] id: FYPO:0001233 name: normal subcellular component def: "A cell phenotype in which the amount, distribution, composition or morphology of a cell part is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal subcellular structure" RELATED [PomBase:al] is_a: FYPO:0007723 ! normal cellular physical quality phenotype created_by: midori creation_date: 2012-07-16T13:59:40Z [Term] id: FYPO:0001234 name: slow vegetative cell population growth def: "A cell population phenotype in which vegetative cell population growth is slower than normal." [PomBase:mah] comment: Use this term when growth rate, e.g. as measured by population doubling time, is reduced. Note that with growth on plates, growth rate can be difficult to assess, so it may be better to use 'decreased cell population growth' (FYPO:0000046). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased cell population proliferation" RELATED [PomBase:vw] synonym: "decreased cell proliferation" RELATED [PomBase:vw] synonym: "decreased vegetative cell population growth rate" EXACT [PomBase:mah] synonym: "growth defect, slow growth" BROAD [PomBase:mah] synonym: "increased doubling time" RELATED [PomBase:vw] synonym: "reduced cell proliferation" RELATED [PomBase:vw] synonym: "reduced vegetative cell population growth rate" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth is_a: FYPO:0002060 ! viable vegetative cell population created_by: midori creation_date: 2012-07-16T14:20:51Z [Term] id: FYPO:0001235 name: decreased extent of cell population growth def: "A cellular process phenotype in which cell growth in a cell population occurs to a lower extent than normal, i.e. the population stops growing earlier than normal." [PomBase:mah] synonym: "reduced extent of cell population growth" EXACT [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth created_by: midori creation_date: 2012-07-16T14:25:09Z [Term] id: FYPO:0001236 name: normal growth on cycloheximide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cycloheximide." [PomBase:mah] synonym: "normal cell population growth in presence of cycloheximide" EXACT [PomBase:mah] synonym: "normal cell population growth on cycloheximide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cycloheximide" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cycloheximide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:25:03Z [Term] id: FYPO:0001237 name: normal growth on cadmium def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cadmium ions." [PomBase:mah] synonym: "normal cell population growth in presence of cadmium" EXACT [PomBase:mah] synonym: "normal cell population growth on cadmium" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on cadmium ion" EXACT [PomBase:mah] synonym: "normal cellular response to cadmium" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cadmium ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on cadmium" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:25:47Z [Term] id: FYPO:0001238 name: normal growth on staurosporine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing staurosporine." [PomBase:mah] synonym: "normal cell population growth in presence of staurosporine" EXACT [PomBase:mah] synonym: "normal cell population growth on staurosporine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to staurosporine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on staurosporine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:27:03Z [Term] id: FYPO:0001239 name: normal growth on tert-butyl hydroperoxide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tert-butyl hydroperoxide (t-BOOH, TBHP)." [PomBase:mah] synonym: "normal cell population growth in presence of tert-butyl hydroperoxide" EXACT [PomBase:mah] synonym: "normal cell population growth on 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:64090] synonym: "normal cell population growth on tert-butyl hydroperoxide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to tert-butyl hydroperoxide" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on t-BOOH" EXACT [PomBase:mah] synonym: "normal growth on TBHP" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on tert-butyl hydroperoxide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:28:00Z [Term] id: FYPO:0001240 name: normal growth on diamide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide, also known as diamide." [PomBase:mah] synonym: "normal cell population growth in presence of diamide" EXACT [PomBase:mah] synonym: "normal cell population growth on diamide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958, PomBase:mah] synonym: "normal cellular response to diamide" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on diamide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:30:45Z [Term] id: FYPO:0001241 name: normal growth on anisomycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing anisomycin." [PomBase:mah] synonym: "normal cell population growth in presence of anisomycin" EXACT [PomBase:mah] synonym: "normal cell population growth on anisomycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to anisomycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on anisomycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:31:50Z [Term] id: FYPO:0001242 name: increased RNA level during cellular response to adenine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to adenine starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to adenine starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to adenine starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to adenine depletion" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to adenine deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to adenine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to adenine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to adenine starvation" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-07-16T15:56:42Z [Term] id: FYPO:0001243 name: increased RNA level during cellular response to thiamine def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to thiamine is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to thiamine" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to thiamine" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to thiamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to thiamine during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to vitamin B1" EXACT [GO:0071301, PomBase:mah] synonym: "increased transcript level during cellular response to thiamine" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-07-16T15:57:59Z [Term] id: FYPO:0001244 name: decreased RNA level during cellular response to thiamine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to thiamine starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to thiamine starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to thiamine starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to thiamine depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to thiamine deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to thiamine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to thiamine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to vitamin B1 starvation" EXACT [GO:0036225, PomBase:mah] synonym: "decreased transcript level during cellular response to thiamine starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to thiamine starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-07-16T16:01:16Z [Term] id: FYPO:0001245 name: sensitive to cobalt def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cobalt ions." [PomBase:mah] synonym: "hypersensitive to cobalt" EXACT [PomBase:mah] synonym: "sensitive to cobalt during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cobalt during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to cobalt ions" EXACT [CHEBI:23336] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-07-16T16:15:13Z [Term] id: FYPO:0001246 name: normal RNA level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to hydrogen peroxide" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-07-17T13:17:07Z [Term] id: FYPO:0001248 name: abnormal regulation of mitotic DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of mitotic DNA replication is abnormal." [PomBase:mah] synonym: "abnormal regulation of DNA replication initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of mitotic DNA replication initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0004756 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2012-07-17T13:25:25Z [Term] id: FYPO:0001249 name: increased origin firing efficiency def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin is higher than in wild type. In cells with increased origin firing efficiency, genomic DNA replication initiates from more origins than wild type, and is completed in more, smaller segments, than wild type." [PMID:18799612, PomBase:mah] synonym: "increased origin firing efficiency during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased origin firing efficiency during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of mitotic DNA replication initiation created_by: midori creation_date: 2012-07-17T13:28:55Z [Term] id: FYPO:0001250 name: decreased origin firing efficiency def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin is lower than in wild type. In cells with decreased origin firing efficiency, genomic DNA replication initiates from fewer origins than wild type, and is completed in fewer, larger segments, than wild type." [PMID:18799612, PomBase:mah] synonym: "decreased origin firing efficiency during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased origin firing efficiency during vegetative growth" EXACT [PomBase:mah] synonym: "reduced origin firing efficiency" EXACT [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of mitotic DNA replication initiation created_by: midori creation_date: 2012-07-17T13:31:48Z [Term] id: FYPO:0001252 name: multinucleate multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum per cell." [PomBase:mah] synonym: "multinucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "multinucleate multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0005277 ! multinucleate multiseptate cell relationship: has_part FYPO:0000061 ! multinucleate vegetative cell relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2012-07-19T15:38:21Z [Term] id: FYPO:0001253 name: elongated multinucleate multiseptate vegetative cell, single septa between nuclei alt_id: FYPO:0005056 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer than normal, has three or more nuclei and two or more septa, and the septa are not grouped together, but are located so as to form separate compartments with a single nucleus in each." [PomBase:mah, PomBase:vw] synonym: "elongated multinucleate multiseptate cell, single septa between nuclei during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate multiseptate vegetative cell, single septa between nuclei during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated multiseptate cell, with three or more nuclei and single septa between nuclei during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multiseptate vegetative cell, with three or more nuclei and single septa between nuclei" EXACT [PomBase:mah] synonym: "elongated multiseptate vegetative cell, with three or more nuclei and single septa between nuclei during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0003343 ! elongated multinucleate multiseptate cell, single septa between nuclei created_by: midori creation_date: 2012-07-19T15:40:18Z [Term] id: FYPO:0001254 name: multinucleate multiseptate vegetative cell, septa grouped def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum, and the septa are grouped together between two compartments, one or more of which may contain multiple nuclei." [PomBase:mah] synonym: "multinucleate multiseptate cell, septa grouped during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multinucleate multiseptate cell, septa grouped during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell is_a: FYPO:0002002 ! multiseptate vegetative cell, septa grouped created_by: midori creation_date: 2012-07-19T15:41:59Z [Term] id: FYPO:0001255 name: increased protein level during cellular response to oxygen def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to the level of oxygen is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to oxygen" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to oxygen during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to oxygen during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to oxygen levels" EXACT [GO:0071453] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-07-19T16:01:11Z [Term] id: FYPO:0001256 name: increased protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "increased protein level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0001549 ! altered protein level during cellular response to hypoxia created_by: midori creation_date: 2012-07-19T16:03:44Z [Term] id: FYPO:0001257 name: normal protein level during cellular response to oxygen def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to the level of oxygen is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to oxygen" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to oxygen during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to oxygen during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to oxygen levels" EXACT [GO:0071453] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2012-07-19T16:05:22Z [Term] id: FYPO:0001258 name: normal protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "normal protein level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2012-07-19T16:06:01Z [Term] id: FYPO:0001259 name: decreased RNA level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "decreased RNA level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to increased oxygen tension" EXACT [GO:0071456] synonym: "decreased transcript level during cellular response to hypoxia" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-07-19T16:07:22Z [Term] id: FYPO:0001260 name: normal RNA level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to hypoxia" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "normal RNA level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to increased oxygen tension" EXACT [GO:0071456] synonym: "normal transcript level during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-07-19T16:10:05Z [Term] id: FYPO:0001261 name: decreased cytokinesis during cellular hyperosmotic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitotic cytokinesis is decreased during a cellular hyperosmotic response." [PomBase:mah] synonym: "decreased cytokinesis during cellular hyperosmotic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytokinesis during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic cytokinesis during cellular hyperosmotic response" EXACT [GO:0000281, PomBase:mah] synonym: "reduced cytokinesis during cellular hyperosmotic response" EXACT [PomBase:mah] is_a: FYPO:0000418 ! decreased cytokinesis created_by: midori creation_date: 2012-07-19T16:20:14Z [Term] id: FYPO:0001262 name: obsolete stubby cell during cellular hyperosmotic response def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which the cell diameter is larger than normal and the cell length is shorter than normal, during a cellular hyperosmotic response." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "stubby cell during cellular hyperosmotic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "stubby cell during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] synonym: "watermelon-shaped cell during cellular hyperosmotic response" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-07-19T16:21:16Z [Term] id: FYPO:0001263 name: obsolete branched, elongated cell during cellular hyperosmotic response def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched and septated, and longer than normal, during a cellular hyperosmotic response." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "branched, elongated cell during cellular hyperosmotic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched, elongated cell during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] synonym: "branched, elongated, septated cell during cellular hyperosmotic response" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2012-07-19T16:22:02Z [Term] id: FYPO:0001264 name: abnormal cell polarity during cellular hyperosmotic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is abnormal during a cellular hyperosmotic response." [PomBase:mah] synonym: "abnormal cell polarity during cellular hyperosmotic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell polarity during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity during cellular hyperosmotic response" EXACT [PomBase:mah] synonym: "cell polarity defects during cellular hyperosmotic response" EXACT [PomBase:mah] is_a: FYPO:0000026 ! abnormal vegetative cell polarity created_by: midori creation_date: 2012-07-19T16:23:32Z [Term] id: FYPO:0001265 name: increased protein phosphorylation during cellular hyperosmotic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular hyperosmotic response." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular hyperosmotic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2012-07-19T16:27:02Z [Term] id: FYPO:0001266 name: normal protein phosphorylation during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2012-07-19T16:28:13Z [Term] id: FYPO:0001267 name: abolished nuclear export during cellular hypotonic salinity response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export does not occur when the cell is subject to a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abolished nuclear export during cellular hypotonic salinity response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent nuclear export during cellular hypotonic salinity response" EXACT [PomBase:mah] synonym: "nuclear export during cellular hypotonic salinity response abolished" EXACT [PomBase:mah] synonym: "nuclear export during cellular hypotonic salinity response abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export in response to salt starvation abolished" EXACT [PomBase:al] is_a: FYPO:0000507 ! abolished nuclear export created_by: midori creation_date: 2012-07-19T16:50:01Z [Term] id: FYPO:0001268 name: abnormal protein localization to kinetochore during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the kinetochore and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0005209 ! abnormal protein localization to kinetochore created_by: midori creation_date: 2012-07-19T16:53:31Z [Term] id: FYPO:0001269 name: abolished protein localization to kinetochore during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to kinetochore abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002902 ! decreased protein localization to kinetochore during vegetative growth created_by: midori creation_date: 2012-07-19T16:54:02Z [Term] id: FYPO:0001270 name: complete but unequal mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation results in the separation of chromosomes into two distinct unequal masses, located at or near the ends of an elongated mitotic spindle." [PMID:22711988, PomBase:mah] synonym: "aneuploidy" RELATED [PomBase:vw] synonym: "complete but unequal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "complete but unequal mitotic sister chromatid separation" RELATED [PomBase:mah] synonym: "complete but unequal mitotic sister chromatid separation during vegetative growth" EXACT [PomBase:mah] synonym: "complete but unequal sister chromatid segregation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003241 ! unequal mitotic sister chromatid segregation created_by: midori creation_date: 2012-07-19T17:05:51Z [Term] id: FYPO:0001271 name: incomplete, unequal mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes; some, but not all, DNA may be moved towards the ends of an elongated mitotic spindle. Chromosomes do not segregate into two equal masses." [PMID:22711988, PomBase:mah] synonym: "incomplete, unequal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid segregation during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid separation" RELATED [PomBase:mah] synonym: "incomplete, unequal sister chromatid segregation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003241 ! unequal mitotic sister chromatid segregation is_a: FYPO:0003757 ! incomplete mitotic sister chromatid segregation created_by: midori creation_date: 2012-07-19T17:09:10Z [Term] id: FYPO:0001272 name: incomplete, unequal mitotic sister chromatid segregation, with smeared DNA def: "A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and DNA becomes spread into an indistinct mass along much of the length of the mitotic spindle." [PMID:22711988, PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid segregation, with smeared DNA during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid separation, with smeared DNA" RELATED [PomBase:mah] synonym: "incomplete, unequal sister chromatid segregation, with smeared DNA during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001271 ! incomplete, unequal mitotic sister chromatid segregation created_by: midori creation_date: 2012-07-19T17:15:07Z [Term] id: FYPO:0001273 name: mitotic spindle elongation with incomplete, unequal mitotic sister chromatid segregation and unseparated DNA def: "A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes, and DNA remains in a single mass at or near the midpoint of the mitotic spindle." [PMID:22711988, PomBase:mah, PomBase:vw] synonym: "mitotic spindle elongation with incomplete, unequal mitotic sister chromatid segregation and unseparated DNA during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle elongation with incomplete, unequal mitotic sister chromatid separation, with unseparated DNA" RELATED [PomBase:mah] synonym: "spindle elongation with incomplete, unequal mitotic sister chromatid segregation and unseparated DNA during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001271 ! incomplete, unequal mitotic sister chromatid segregation is_a: FYPO:0003758 ! mitotic spindle elongation without chromosome separation created_by: midori creation_date: 2012-07-19T17:15:33Z [Term] id: FYPO:0001274 name: decreased protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to hypoxic stress" EXACT [GO:0071456] synonym: "decreased protein level during cellular response to lowered oxygen tension" EXACT [GO:0071456] synonym: "reduced protein level during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0001549 ! altered protein level during cellular response to hypoxia created_by: midori creation_date: 2012-07-19T17:21:36Z [Term] id: FYPO:0001275 name: decreased protein-protein interaction during cellular response to hypoxia def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hypoxia. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding during cellular response to hypoxia" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction in response to hypoxia" RELATED [PomBase:al] synonym: "reduced protein-protein interaction during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction created_by: midori creation_date: 2012-07-19T17:23:30Z [Term] id: FYPO:0001276 name: decreased MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of MCM complex assembly is decreased." [PomBase:mah] synonym: "decreased MCM complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased MCM complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced MCM complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000448 ! abnormal MCM complex assembly created_by: midori creation_date: 2012-07-20T17:32:31Z [Term] id: FYPO:0001277 name: abolished MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is abolished." [PomBase:mah] synonym: "abolished MCM complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished MCM complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "MCM complex assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0000448 ! abnormal MCM complex assembly created_by: midori creation_date: 2012-07-20T17:34:14Z [Term] id: FYPO:0001278 name: normal MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal MCM complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal MCM complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2012-07-20T17:36:38Z [Term] id: FYPO:0001279 name: increased RNA level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to oxidative stress" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during oxidative stress response" EXACT [PomBase:vw] synonym: "increased transcript level during cellular response to oxidative stress" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-07-26T10:59:25Z [Term] id: FYPO:0001280 name: decreased RNA level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to oxidative stress" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to DEM" NARROW [PomBase:al] synonym: "decreased RNA level during cellular response to diethyl maleate" NARROW [PomBase:mah] synonym: "decreased RNA level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during oxidative stress response" EXACT [PomBase:vw] synonym: "decreased transcript level during cellular response to oxidative stress" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-07-26T11:06:41Z [Term] id: FYPO:0001281 name: normal protein phosphorylation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2012-07-26T11:15:18Z [Term] id: FYPO:0001282 name: abnormal chromatin organization during nitrogen starvation def: "A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is subject to nitrogen starvation. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal chromatin organisation during nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal chromatin organization during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2012-07-26T11:50:10Z [Term] id: FYPO:0001283 name: decreased protein level during cellular response to nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to nitrogen starvation is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to nitrogen starvation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased protein level during cellular response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased protein level during nitrogen starvation" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation created_by: midori creation_date: 2012-07-26T11:59:16Z [Term] id: FYPO:0001284 name: phosphatidylserine absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is too low to detect." [PomBase:mah] synonym: "phosphatidyl-L-serine absent from cell" EXACT [CHEBI:18303] synonym: "phosphatidylserine absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "phosphatidylserine absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "PS absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0001289 ! decreased phospholipid level created_by: midori creation_date: 2012-07-26T12:20:15Z [Term] id: FYPO:0001285 name: decreased cellular phosphatidylethanolamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular PE level" EXACT [PomBase:mah] synonym: "decreased cellular phosphatidylethanolamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphatidylethanolamine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased phosphatidylethanolamine accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphatidylethanolamine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-26T12:25:19Z [Term] id: FYPO:0001286 name: increased cellular phosphoinositide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell is higher than normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." [PomBase:mah] synonym: "increased cellular phosphoinositide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphoinositide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PI level" RELATED [PomBase:al] synonym: "increased PI accumulation" RELATED [PomBase:al] is_a: FYPO:0001290 ! altered cellular phosphoinositide level is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-26T12:26:35Z [Term] id: FYPO:0001287 name: altered phospholipid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell differs from normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester." [CHEBI:16247, PomBase:mah] synonym: "abnormal phospholipid level" EXACT [PomBase:mah] synonym: "altered cellular phospholipid level" EXACT [PomBase:mah] synonym: "altered phospholipid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered phospholipid level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-26T13:16:37Z [Term] id: FYPO:0001288 name: increased phospholipid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell is higher than normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester." [CHEBI:16247, PomBase:mah] synonym: "increased cellular phospholipid level" EXACT [PomBase:mah] synonym: "increased phospholipid accumulation" RELATED [PomBase:mah] synonym: "increased phospholipid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phospholipid level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001287 ! altered phospholipid level created_by: midori creation_date: 2012-07-26T13:21:43Z [Term] id: FYPO:0001289 name: decreased phospholipid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell is lower than normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester." [CHEBI:16247, PomBase:mah] synonym: "decreased cellular phospholipid level" EXACT [PomBase:mah] synonym: "decreased phospholipid accumulation" RELATED [PomBase:mah] synonym: "decreased phospholipid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phospholipid level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced phospholipid level" EXACT [PomBase:mah] is_a: FYPO:0001287 ! altered phospholipid level created_by: midori creation_date: 2012-07-26T13:22:15Z [Term] id: FYPO:0001290 name: altered cellular phosphoinositide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell differs from normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." [PomBase:mah] synonym: "abnormal cellular phosphoinositide level" EXACT [PomBase:mah] synonym: "altered cellular phosphoinositide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered cellular phosphoinositide level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular PI level" RELATED [PomBase:al] synonym: "altered PI accumulation" RELATED [PomBase:al] is_a: FYPO:0001287 ! altered phospholipid level created_by: midori creation_date: 2012-07-26T13:23:26Z [Term] id: FYPO:0001291 name: abnormal CDP-diacylglycerol-serine O-phosphatidyltransferase activity def: "A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-07-26T13:33:37Z [Term] id: FYPO:0001292 name: decreased CDP-diacylglycerol-serine O-phosphatidyltransferase activity def: "A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is decreased." [PomBase:mah] synonym: "reduced CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001291 ! abnormal CDP-diacylglycerol-serine O-phosphatidyltransferase activity created_by: midori creation_date: 2012-07-26T13:34:04Z [Term] id: FYPO:0001293 name: normal cell wall biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell wall biogenesis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell wall biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell wall biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "normal fungal-type cell wall biogenesis" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-07-26T13:49:47Z [Term] id: FYPO:0001294 name: normal actin cortical patch localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin cortical patch localisation" EXACT [PomBase:mah] synonym: "normal actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actin cortical patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal actin cortical patch location" RELATED [PomBase:mah] synonym: "normal actin patch localization" EXACT [PomBase:mah] synonym: "normal F-actin patch localization" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-07-26T14:12:03Z [Term] id: FYPO:0001295 name: normal palmitoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-07-26T14:25:18Z [Term] id: FYPO:0001296 name: normal oleoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal oleoyl-CoA synthetase activity" EXACT [GO:0090434, PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-07-26T14:31:43Z [Term] id: FYPO:0001297 name: abnormal palmitoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:33:36Z [Term] id: FYPO:0001298 name: decreased palmitoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] synonym: "reduced palmitoyl-CoA ligase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001297 ! abnormal palmitoyl-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:34:05Z [Term] id: FYPO:0001299 name: abolished palmitoyl-CoA ligase activity def: "A molecular function phenotype in which palmitoyl-CoA ligase activity is absent." [PomBase:mah] synonym: "abolished palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] synonym: "palmitoyl-CoA ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001297 ! abnormal palmitoyl-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:34:26Z [Term] id: FYPO:0001300 name: abnormal oleoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal oleoyl-CoA synthetase activity" EXACT [GO:0090434, PomBase:mah] is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:38:21Z [Term] id: FYPO:0001301 name: abolished oleoyl-CoA ligase activity def: "A molecular function phenotype in which oleoyl-CoA ligase activity is absent." [PomBase:mah] synonym: "abolished oleoyl-CoA synthetase activity" EXACT [GO:0090434, PomBase:mah] synonym: "oleoyl-CoA ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001300 ! abnormal oleoyl-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:38:28Z [Term] id: FYPO:0001302 name: decreased oleoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased oleoyl-CoA synthetase activity" RELATED [GO:0090434, PomBase:mah] synonym: "reduced oleoyl-CoA ligase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001300 ! abnormal oleoyl-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:38:38Z [Term] id: FYPO:0001303 name: abnormal myristoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of myristoyl-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal myristoyl-CoA synthetase activity" EXACT [GO:0090432, PomBase:mah] is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:40:40Z [Term] id: FYPO:0001304 name: decreased myristoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of myristoyl-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased myristoyl-CoA synthetase activity" RELATED [GO:0090432, PomBase:mah] synonym: "reduced myristoyl-CoA ligase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001303 ! abnormal myristoyl-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:40:44Z [Term] id: FYPO:0001305 name: abnormal long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which the observed rate of any long-chain fatty acid-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal lcfa-ligase activity" EXACT [PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-07-26T14:44:02Z [Term] id: FYPO:0001306 name: abolished long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which long-chain fatty acid-CoA ligase activity is absent." [PomBase:mah] synonym: "abolished lcfa-ligase activity" EXACT [PomBase:al] synonym: "long-chain fatty acid-CoA ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:45:16Z [Term] id: FYPO:0001307 name: decreased long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which the observed rate of long-chain fatty acid-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased lcfa-ligase activity" EXACT [PomBase:al] synonym: "reduced long-chain fatty acid-CoA ligase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:45:21Z [Term] id: FYPO:0001308 name: increased long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which the observed rate of long-chain fatty acid-CoA ligase activity is increased." [PomBase:mah] synonym: "increased lcfa-ligase activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:45:26Z [Term] id: FYPO:0001309 name: increased viability in stationary phase def: "A cell population phenotype in which a larger than normal proportion of cells in the population remains viable after entering stationary phase." [PomBase:mah] synonym: "decreased chronological cell aging" RELATED [PomBase:vw] synonym: "increased cell population viability in stationary phase" EXACT [PomBase:mah] synonym: "increased chronological lifespan" RELATED [PomBase:vw] synonym: "increased longevity" EXACT [] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2012-07-26T14:58:27Z [Term] id: FYPO:0001310 name: normal viability in stationary phase def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase." [PomBase:mah] synonym: "normal cell population viability in stationary phase" EXACT [PomBase:mah] synonym: "normal chronological cell aging" RELATED [PomBase:vw] synonym: "normal chronological lifespan" RELATED [PomBase:vw] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2012-07-26T14:59:20Z [Term] id: FYPO:0001311 name: decreased plasmid loss def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which plasmids are lost at a lower frequency than normal. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation." [PomBase:mah] synonym: "decreased plasmid loss during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased plasmid loss during vegetative growth" EXACT [PomBase:mah] synonym: "reduced plasmid loss" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2012-07-26T15:11:43Z [Term] id: FYPO:0001312 name: normal vegetative phenotype def: "A normal phenotype that is observed when cells are in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "fission yeast normal vegetative phenotype" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-08-01T11:18:45Z [Term] id: FYPO:0001313 name: normal subcellular component during vegetative growth def: "A cell phenotype in which the amount, distribution, or morphology of a cell part is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal subcellular component during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal subcellular structure during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T12:32:26Z [Term] id: FYPO:0001314 name: normal cell cortex morphology during vegetative growth def: "A physical cellular phenotype in which the size, shape, and structure of the cell cortex are normal when the cell is in the vegetative growth phase of the life cycle. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] synonym: "normal cell cortex morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001231 ! normal cell cortex morphology is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2012-08-01T12:33:02Z [Term] id: FYPO:0001315 name: normal vegetative cell morphology def: "A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal cell morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal vegetative cell morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000672 ! normal cell morphology is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T13:09:00Z [Term] id: FYPO:0001316 name: normal level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell is normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal level of substance in cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001076 ! normal level of substance in cell is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T13:14:57Z [Term] id: FYPO:0001317 name: normal RNA level during vegetative growth alt_id: FYPO:0002938 def: "A cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mRNA accumulation" RELATED [PomBase:mah] synonym: "normal mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "normal mRNA transcript level during vegetative growth" NARROW [PomBase:mah] synonym: "normal RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcript level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T13:15:43Z [Term] id: FYPO:0001318 name: normal cellular response to chemical stimulus during vegetative growth def: "A cellular response phenotype in which the cellular response to a chemical stimulus is normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal cellular response to chemical stimulus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000953 ! normal cellular response to chemical stimulus created_by: midori creation_date: 2012-08-01T13:37:42Z [Term] id: FYPO:0001319 name: normal cellular process during vegetative growth def: "A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal cellular process during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T13:42:47Z [Term] id: FYPO:0001320 name: vegetative cell phenotype def: "A phenotype that is observed at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cell phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast vegetative cell phenotype" EXACT [PomBase:mah] synonym: "vegetative cell phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vegetative cell phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2012-08-01T13:52:18Z [Term] id: FYPO:0001321 name: cellular physical quality phenotype during vegetative growth def: "A phenotype that affects any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cellular physical object quality phenotype during vegetative growth" EXACT [PATO:0001241] synonym: "cellular physical quality phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fission yeast cellular physical object quality phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000136 ! cellular physical quality phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T14:44:55Z [Term] id: FYPO:0001322 name: abnormal subcellular component during vegetative growth def: "A physical cellular phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal subcellular component during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal subcellular structure during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T14:46:27Z [Term] id: FYPO:0001323 name: altered level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal level of substance in cell during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of substance in cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T14:57:41Z [Term] id: FYPO:0001324 name: decreased protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-08-01T15:37:56Z [Term] id: FYPO:0001325 name: altered protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular protein level during vegetative growth" EXACT [PomBase:mah] synonym: "altered protein level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000834 ! altered protein level is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T15:11:16Z [Term] id: FYPO:0001326 name: altered RNA level during vegetative growth alt_id: FYPO:0002934 def: "A cell phenotype in which the amount of RNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Also, consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term or its descendants. subset: qc_do_not_manually_annotate synonym: "abnormal mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "abnormal RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular messenger RNA level during vegetative growth" NARROW [PomBase:mah] synonym: "altered cellular mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "altered cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "altered mRNA transcript level during vegetative growth" NARROW [PomBase:vw] synonym: "altered RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered transcript level during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000824 ! altered RNA level is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T15:11:33Z [Term] id: FYPO:0001327 name: increased protein level during vegetative growth alt_id: FYPO:0000762 def: "A cell phenotype in which the amount of protein measured in a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000836 ! increased protein level is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-08-01T15:43:39Z [Term] id: FYPO:0001328 name: abnormal cytoskeleton organization during vegetative growth def: "A cellular process phenotype in which cytoskeleton organization is abnormal in the vegetative growth phase of the cell cycle." [GO:0007010, PomBase:mah] comment: Consider annotating to 'abnormal cytoskeleton' (FYPO:0002397), but note that an abnormal cytoskeleton organization process may, but does not necessarily, result in a physically abnormal cytoskeleton. synonym: "abnormal cytoskeleton organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cytoskeleton organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000802 ! abnormal cytoskeleton organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-08-02T17:17:46Z [Term] id: FYPO:0001329 name: decreased level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased level of substance in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced level of substance in cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T16:23:22Z [Term] id: FYPO:0001330 name: increased level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "increased accumulation of substance in cell during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of substance in cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000990 ! increased level of substance in cell is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T16:24:14Z [Term] id: FYPO:0001331 name: cellular process phenotype during vegetative growth def: "A phenotype that affects a cellular process in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cellular process phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fission yeast cellular process phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T16:27:01Z [Term] id: FYPO:0001332 name: abnormal regulation of translation in response to stress during vegetative growth def: "A gene expression phenotype in which regulation of translation in response to stress is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal regulation of translation in response to stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein synthesis after stress, defective during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth is_a: FYPO:0005044 ! translation regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:31:58Z [Term] id: FYPO:0001333 name: gene expression regulation phenotype during vegetative growth def: "A regulation phenotype that affects the regulation of gene expression in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast gene expression regulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "gene expression regulation phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype created_by: midori creation_date: 2012-08-01T16:33:19Z [Term] id: FYPO:0001334 name: regulation phenotype during vegetative growth def: "A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast regulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "regulation phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:33:52Z [Term] id: FYPO:0001335 name: transcription regulation phenotype during vegetative growth def: "A gene expression phenotype that affects the regulation of DNA-dependent transcription in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast transcription regulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "gene-specific transcription regulation phenotype during vegetative growth" RELATED [GO:0006355, PomBase:mah] synonym: "transcription regulation phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "transcriptional control phenotype during vegetative growth" BROAD [GO:0006355, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:36:22Z [Term] id: FYPO:0001336 name: transport phenotype during vegetative growth def: "A cell process phenotype that affects a transport process in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast transport phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "transport phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000149 ! transport phenotype is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:55:04Z [Term] id: FYPO:0001337 name: localization phenotype during vegetative growth def: "A cell phenotype that affects the localization of a structure or substance in a cell in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast localization phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "localisation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "localization phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:55:18Z [Term] id: FYPO:0001338 name: abnormal nucleus positioning during vegetative growth def: "A cellular process phenotype in which nucleus localization is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal nuclear localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleus localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleus localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleus localization during vegetative growth" EXACT [] is_a: FYPO:0000517 ! abnormal nucleus positioning is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:07:26Z [Term] id: FYPO:0001339 name: abnormal cellular response to starvation during vegetative growth def: "A stress response phenotype in which the response to starvation for one or more nutrients is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal cellular response to depletion during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal cellular response to deprivation during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal cellular response to starvation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000713 ! abnormal cellular response to starvation is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-01T17:15:31Z [Term] id: FYPO:0001340 name: abnormal cellular response to oxidative stress during vegetative growth def: "A stress response phenotype in which a cellular response to oxidative stress is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Use this term if you have assayed the response to oxidative stress at the subcellular or molecular level. If you have assayed growth of cells exposed to oxidative stress in culture, use 'sensitive to oxidative stress' (FYPO:0000726). synonym: "abnormal cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal oxidative stress response during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000180 ! abnormal cellular response to oxidative stress is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-01T17:18:23Z [Term] id: FYPO:0001341 name: abnormal cellular response to stress during vegetative growth def: "A cellular response phenotype in which a cellular response to stress is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Use this term if you have assayed the response to a stress at the subcellular or molecular level. If you have assayed growth of cells exposed to the stress in culture, use 'sensitive to stress during vegetative growth' (FYPO:0000304) or 'resistance to stress during vegetative growth' (FYPO:0000850) or a more specific term. synonym: "abnormal cellular response to stress during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress created_by: midori creation_date: 2012-08-01T17:19:19Z [Term] id: FYPO:0001342 name: cellular response phenotype during vegetative growth def: "A cellular process phenotype that affects a response to a stimulus in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "cellular response phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fission yeast cellular response phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:32:10Z [Term] id: FYPO:0001343 name: abnormal mitotic DNA replication def: "A cellular process phenotype in which DNA replication is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal DNA replication during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal DNA replication during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000217 ! abnormal DNA replication is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:33:51Z [Term] id: FYPO:0001344 name: abnormal mitotic DNA replication initiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA replication initiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal DNA replication initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000176 ! abnormal DNA replication initiation is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2012-08-01T17:34:25Z [Term] id: FYPO:0001345 name: abnormal DNA recombination during vegetative growth def: "A cellular process phenotype in which DNA recombination is abnormal in the vegetative growth phase of the life cycle. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents." [GO:0006310, PomBase:mah] synonym: "abnormal DNA recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal recombination during vegetative growth" EXACT [PomBase:vw] synonym: "recombination defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2012-08-01T17:37:10Z [Term] id: FYPO:0001346 name: DNA metabolism phenotype during vegetative growth def: "A cellular process phenotype that affects any DNA metabolic process in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "DNA metabolism phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fission yeast DNA metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:38:00Z [Term] id: FYPO:0001347 name: nucleic acid metabolism phenotype during vegetative growth def: "A cellular process phenotype that affects any nucleic acid metabolic process in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast nucleic acid metabolism phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "nucleic acid metabolism phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000292 ! nucleic acid metabolism phenotype is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:39:21Z [Term] id: FYPO:0001348 name: cellular metabolism phenotype during vegetative growth def: "A cellular process phenotype that affects metabolism in the cell in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cellular metabolism phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fission yeast cellular metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:40:24Z [Term] id: FYPO:0001350 name: abnormal microtubule cytoskeleton organization during vegetative growth def: "A phenotype that affects the organization of the microtubule cytoskeleton in the vegetative growth phase of the life cycle. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] comment: Consider annotating to 'abnormal microtubule cytoskeleton' (FYPO:0002399), but note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in a physically abnormal microtubule cytoskeleton. synonym: "abnormal microtubule cytoskeleton organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal microtubule cytoskeleton organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal microtubule organisation during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal microtubule organization during vegetative growth" RELATED [PomBase:mah] synonym: "disorganized microtubule cytoskeleton during vegetative growth" RELATED [PomBase:vw] synonym: "microtubule cytoskeleton defects during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defects during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization is_a: FYPO:0001328 ! abnormal cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-08-01T17:45:38Z [Term] id: FYPO:0001351 name: abnormal membrane organization during vegetative growth def: "A cellular process phenotype in which cellular membrane organization is abnormal in the vegetative growth phase of the life cycle. Cellular membrane organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid bilayer membrane, such as the plasma membrane or an organelle membrane." [GO:0061024, PomBase:mah] synonym: "abnormal cellular membrane organization during vegetative growth" EXACT [GO:0061024, PomBase:mah] synonym: "abnormal membrane organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal membrane organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001013 ! abnormal membrane organization created_by: midori creation_date: 2012-08-01T17:51:07Z [Term] id: FYPO:0001352 name: abnormal chromatin organization during vegetative growth def: "A cellular process phenotype in which any process of chromatin organization is abnormal in the vegetative growth phase of the life cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] synonym: "abnormal chromatin organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2012-08-01T17:56:15Z [Term] id: FYPO:0001353 name: abnormal cellular component organization during vegetative growth def: "A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal in the vegetative growth phase of the life cycle." [GO:0016043, PomBase:mah] synonym: "abnormal cellular component organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular component organization at cellular level during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular component organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T18:11:39Z [Term] id: FYPO:0001354 name: abnormal cellular component assembly during vegetative growth def: "A cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal cellular component assembly at cellular level during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular component assembly during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-08-01T18:14:28Z [Term] id: FYPO:0001355 name: decreased vegetative cell population growth def: "A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both." [PomBase:mah] synonym: "aerobic vegetative growth defects" RELATED [PomBase:mah] synonym: "decreased vegetative aerobic cell population growth" NARROW [PomBase:mah] synonym: "reduced vegetative aerobic cell population growth" NARROW [PomBase:mah] synonym: "reduced vegetative cell population growth" EXACT [PomBase:mah] synonym: "reduced vegetative growth" BROAD [PomBase:mah] synonym: "slow vegetative aerobic cell population growth" NARROW [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth is_a: FYPO:0001356 ! abnormal vegetative cell population growth is_a: FYPO:0002060 ! viable vegetative cell population created_by: midori creation_date: 2012-08-01T18:16:46Z [Term] id: FYPO:0001356 name: abnormal vegetative cell population growth def: "A cellular process phenotype in which vegetative cell population growth is abnormal. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "vegetative growth defect" RELATED [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth is_a: FYPO:0001358 ! vegetative cell population growth phenotype created_by: midori creation_date: 2012-08-01T18:17:46Z [Term] id: FYPO:0001357 name: normal vegetative cell population growth def: "A cell population phenotype in which a population of cells grows normally (i.e. indistinguishably from wild type) in the vegetative growth phase of the life cycle. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] synonym: "vegetative growth normal" BROAD [PomBase:mah] synonym: "vegetative population growth normal" EXACT [PomBase:mah] is_a: FYPO:0000047 ! normal cell population growth is_a: FYPO:0001358 ! vegetative cell population growth phenotype is_a: FYPO:0002060 ! viable vegetative cell population created_by: midori creation_date: 2012-08-01T18:20:01Z [Term] id: FYPO:0001358 name: vegetative cell population growth phenotype def: "A cell phenotype that affects the rate or extent of cell population growth in the vegetative growth phase of the life cycle. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cell population growth phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast cell population growth phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "vegetative cell population growth phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000139 ! cell population growth phenotype created_by: midori creation_date: 2012-08-01T18:21:02Z [Term] id: FYPO:0001360 name: decreased amino acid import during vegetative growth def: "A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased amino acid import across plasma membrane during vegetative growth" EXACT [GO:0089718] synonym: "decreased amino acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased amino acid import into cell during vegetative growth" EXACT [PomBase:al] synonym: "decreased amino acid uptake during vegetative growth" EXACT [PomBase:mah] synonym: "reduced amino acid import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001058 ! decreased amino acid import is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-08-02T14:51:40Z [Term] id: FYPO:0001361 name: abnormal amino acid import during vegetative growth def: "A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal amino acid import across plasma membrane during vegetative growth" EXACT [GO:0089718] synonym: "abnormal amino acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal amino acid import into cell during vegetative growth" EXACT [PomBase:al] synonym: "abnormal amino acid uptake during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001057 ! abnormal amino acid import is_a: FYPO:0001336 ! transport phenotype during vegetative growth created_by: midori creation_date: 2012-08-02T14:52:32Z [Term] id: FYPO:0001362 name: abnormal cellular process during vegetative growth def: "A phenotype in which a specific cellular process is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal cellular process during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-02T14:55:51Z [Term] id: FYPO:0001363 name: abnormal metabolic process during vegetative growth def: "A cellular process phenotype in which a cellular metabolic process is abnormal in the vegetative growth phase of the life cycle. A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] synonym: "abnormal cellular metabolic process during vegetative growth" EXACT [GO:0044237, PomBase:mah] synonym: "abnormal metabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal metabolism during vegetative growth" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-02T18:07:32Z [Term] id: FYPO:0001364 name: abnormal actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is abnormal. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "abnormal actomyosin contractile ring constriction" EXACT [PomBase:vw] synonym: "abnormal actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring contraction" EXACT [PomBase:vw] synonym: "abnormal cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "abnormal mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "abnormal mitotic contractile ring contraction" EXACT [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2012-08-07T12:39:39Z [Term] id: FYPO:0001365 name: decreased rate of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring contraction is decreased. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "decreased rate of actomyosin contractile ring constriction" EXACT [PomBase:mah] synonym: "decreased rate of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of contractile ring contraction" EXACT [PomBase:vw] synonym: "decreased rate of cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "decreased rate of mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "decreased rate of mitotic contractile ring contraction" EXACT [PomBase:vw] synonym: "reduced rate of actomyosin contractile ring contraction" EXACT [PomBase:mah] is_a: FYPO:0000419 ! decreased rate of cytokinesis is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2012-08-07T12:41:50Z [Term] id: FYPO:0001366 name: normal actin cytoskeleton organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is normal (i.e. indistinguishable from wild type). Actin cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GO:0030036, PomBase:mah] synonym: "normal actin cytoskeleton organisation" EXACT [PomBase:mah] synonym: "normal actin cytoskeleton organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actin cytoskeleton organization during vegetative growth" EXACT [PomBase:mah] synonym: "normal actin filament organization" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-08-07T12:51:48Z [Term] id: FYPO:0001367 name: normal cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis is normal (i.e. indistinguishable from wild type). Cytokinesis is part of the cell cycle and results in the division of the cytoplasm of a cell and its separation into two daughter cells." [GO:0000281, PomBase:mah] synonym: "normal cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "normal cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic cytokinesis" EXACT [GO:0000281, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-08-07T12:54:44Z [Term] id: FYPO:0001368 name: normal actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:vw] synonym: "normal contractile ring assembly" EXACT [PomBase:mah] synonym: "normal cytokinesis, actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "normal cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "normal cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "normal cytokinetic ring formation" RELATED [PomBase:vw] synonym: "normal mitotic contractile ring assembly" EXACT [PomBase:vw] is_a: FYPO:0001366 ! normal actin cytoskeleton organization is_a: FYPO:0001367 ! normal cytokinesis created_by: midori creation_date: 2012-08-07T12:54:57Z [Term] id: FYPO:0001369 name: mislocalized actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring in an abnormal location. The normal location is at the midpoint of, and perpendicular to, the long axis of the cell." [PomBase:mah] comment: Note that the location of the contractile ring is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. Consider also annotating to 'mislocalized septum' (FYPO:0000339) because if the contractile ring forms in an abnormal location, the septum will also do so. synonym: "contractile ring displaced from cell centre" EXACT [PomBase:vw] synonym: "mislocalised actomyosin contractile ring" EXACT [PomBase:mah] synonym: "mislocalized actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "mislocalized mitotic contractile ring" EXACT [PomBase:vw] is_a: FYPO:0004736 ! abnormal actomyosin contractile ring relationship: output_of FYPO:0000033 ! abnormal actomyosin contractile ring localization created_by: midori creation_date: 2012-08-07T13:31:19Z [Term] id: FYPO:0001370 name: abnormal protein localization def: "A cell phenotype in which the localization of a protein in a cell is abnormal. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: We recommend using a more specific term if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abnormal cellular protein localisation" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization" EXACT [PomBase:mah] synonym: "abnormal protein localisation" EXACT [PomBase:mah] synonym: "protein/peptide distribution: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0002333 ! protein localization phenotype created_by: midori creation_date: 2012-08-07T13:40:05Z [Term] id: FYPO:0001371 name: abolished protein localization to medial cortex def: "A cell phenotype in which the localization of a protein to the medial cortex is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein localisation to medial cortex abolished" EXACT [GO:0071574, PomBase:mah] synonym: "protein localization to medial cortex abolished" EXACT [PomBase:mah] synonym: "protein localization to medial ring abolished" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001373 ! abnormal protein localization to medial cortex is_a: FYPO:0001375 ! abolished protein localization created_by: midori creation_date: 2012-08-07T13:55:44Z [Term] id: FYPO:0001372 name: abnormal protein localization to medial cortex in spores def: "A cell phenotype in which the localization of a protein to the medial cortex of a spore is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortex in spores" EXACT [GO:0071574, PomBase:mah] synonym: "abnormal protein localization to medial ring in spores" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001373 ! abnormal protein localization to medial cortex created_by: midori creation_date: 2012-08-07T13:49:04Z [Term] id: FYPO:0001373 name: abnormal protein localization to medial cortex def: "A cell phenotype in which the localization of a protein to the medial cortex is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortex" EXACT [GO:0071574, PomBase:mah] synonym: "abnormal protein localization to medial ring" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-08-07T13:49:11Z [Term] id: FYPO:0001374 name: abolished protein localization to medial cortex in spores def: "A cell phenotype in which the localization of a protein to the medial cortex of a spore is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein localisation to medial cortex abolished in spores" EXACT [GO:0071574, PomBase:mah] synonym: "protein localization to medial cortex abolished in spores" EXACT [PomBase:mah] synonym: "protein localization to medial ring abolished in spores" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001371 ! abolished protein localization to medial cortex is_a: FYPO:0001372 ! abnormal protein localization to medial cortex in spores created_by: midori creation_date: 2012-08-07T13:56:10Z [Term] id: FYPO:0001375 name: abolished protein localization def: "A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found." [PomBase:mah] comment: If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "protein absent from specific location in cell" RELATED [PomBase:mah] synonym: "protein localisation abolished" EXACT [PomBase:mah] synonym: "protein localization abolished" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-08-07T13:56:37Z [Term] id: FYPO:0001376 name: normal cellular calcium level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular calcium accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal cellular calcium ion level during cellular response to salt stress" EXACT [PomBase:mah] synonym: "normal cellular calcium level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular calcium level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001199 ! normal cellular calcium level created_by: midori creation_date: 2012-08-07T14:56:53Z [Term] id: FYPO:0001377 name: decreased cellular calcium level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is lower than normal." [PomBase:mah] synonym: "decreased calcium accumulation during cellular response to salt stress" RELATED [PomBase:al] synonym: "decreased cellular calcium ion level during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased cellular calcium level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular calcium level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular calcium level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001197 ! decreased cellular calcium level created_by: midori creation_date: 2012-08-07T14:58:22Z [Term] id: FYPO:0001378 name: increased cellular calcium level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is higher than normal." [PomBase:mah] synonym: "increased calcium accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "increased cellular calcium ion level during cellular response to salt stress" EXACT [PomBase:mah] synonym: "increased cellular calcium level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular calcium level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001198 ! increased cellular calcium level created_by: midori creation_date: 2012-08-07T14:58:54Z [Term] id: FYPO:0001379 name: resistance to tacrolimus def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tacrolimus than normal." [PomBase:mah] synonym: "resistance to FK506" EXACT [CHEBI:61057, PomBase:mah] synonym: "resistance to tacrolimus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tacrolimus during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tacrolimus" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-07T15:05:20Z [Term] id: FYPO:0001380 name: normal nuclear morphology during vegetative growth def: "A physical cellular phenotype in which the size, shape, or structure of the nucleus is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal nuclear morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth is_a: FYPO:0001673 ! normal nuclear morphology created_by: midori creation_date: 2012-08-07T15:06:55Z [Term] id: FYPO:0001381 name: abnormal protein kinase activity def: "A molecular function phenotype in which the observed rate of a protein kinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-09T16:05:03Z [Term] id: FYPO:0001382 name: decreased protein kinase activity def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased." [PomBase:mah] synonym: "reduced protein kinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2012-08-09T16:06:18Z [Term] id: FYPO:0001383 name: normal DNA content def: "A cell phenotype in which the amount of DNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2012-08-09T16:33:17Z [Term] id: FYPO:0001384 name: abolished protein kinase activity def: "A molecular function phenotype in which a protein kinase activity is absent." [PomBase:mah] synonym: "protein kinase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2012-08-10T13:54:04Z [Term] id: FYPO:0001385 name: inviable after spore germination, without cell division, cell cycle arrest with replicated DNA def: "A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest with replicated DNA, and eventually dies." [PMID:9705504, PomBase:mah] synonym: "inviable following spore germination, without cell division, cell cycle arrest with replicated DNA" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, cell cycle arrest with replicated DNA" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, cell cycle arrest with replicated DNA" EXACT [PomBase:mah] is_a: FYPO:0000444 ! abnormal mitotic cell cycle arrest with replicated DNA is_a: FYPO:0001924 ! inviable after spore germination, without cell division, cell cycle arrest created_by: midori creation_date: 2012-08-10T14:06:51Z [Term] id: FYPO:0001386 name: increased haploidization alt_id: FYPO:0001781 def: "A cell phenotype in which non-sporulating diploid cells become haploid, without undergoing meiosis, at a higher frequency than normal." [PMID:9914167, PomBase:al, PomBase:mah] comment: Diploid cells may become haploid by chromosome loss, or by undergoing premature mitosis. Chromosome loss may also cause aneuploidy or cell death. synonym: "increased haploidisation" EXACT [PomBase:mah] synonym: "unstable diploid" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2012-08-10T14:51:16Z [Term] id: FYPO:0001387 name: loss of viability at high temperature def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are grown at a temperature higher than standard." [PomBase:mah] comment: For S. pombe, high temperature usually means above 32 degrees C. Use this term to annotate experiments in which a culture is grown at high temperature, and then the number of cells viable enough to form a colony upon return to standard or low temperature is measured and compared to wild type. synonym: "decreased viability at high temperature" EXACT [PomBase:mah] synonym: "loss of cell population viability at high temperature" EXACT [PomBase:mah] synonym: "loss of viability at restrictive temperature" RELATED [PomBase:mah] synonym: "reduced viability at high temperature" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2012-08-10T14:55:36Z [Term] id: FYPO:0001388 name: decreased protein level in germinating spore def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal during or just after spore germination. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "reduced protein level in germinating spore" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2012-08-10T16:32:24Z [Term] id: FYPO:0001389 name: normal nucleus positioning def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleus localization is normal." [PomBase:mah] synonym: "normal nuclear localization" EXACT [PomBase:mah] synonym: "normal nuclear position" EXACT [PomBase:mah] synonym: "normal nucleus localisation" EXACT [PomBase:mah] synonym: "normal nucleus localization" EXACT [] synonym: "normal nucleus localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleus localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007913 ! normal organelle localization created_by: midori creation_date: 2012-08-15T11:46:28Z [Term] id: FYPO:0001390 name: misoriented septum during vegetative growth def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is not perpendicular to the long axis of the cell." [PomBase:mah] comment: Consider also annotating to 'angled actomyosin contractile ring' (FYPO:0002027) because if the contractile ring forms at an abnormal angle, the septum will also do so. synonym: "abnormal septum orientation during vegetative growth" EXACT [PomBase:mah] synonym: "misoriented septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "tilted septum during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0002455 ! abnormal septum during vegetative growth created_by: midori creation_date: 2012-08-15T13:03:09Z [Term] id: FYPO:0001391 name: mislocalized septum, near new end def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum closer to the new end of the cell (when the new end is not yet growing), instead of at the midpoint of the long axis." [PomBase:mah] synonym: "abnormal septum location, near new end" EXACT [PomBase:mah] synonym: "abnormal septum location, near non-growing end" NARROW [PomBase:mah] synonym: "abnormal septum position, near new end" EXACT [PomBase:mah] synonym: "abnormal septum position, near non-growing end" NARROW [PomBase:mah] synonym: "asymmetric septum, near new end" EXACT [PomBase:mah] synonym: "asymmetric septum, near non-growing end" NARROW [PomBase:mah] synonym: "asymmetrically located septum, near new end" EXACT [PomBase:mah] synonym: "asymmetrically located septum, near non-growing end" NARROW [PomBase:mah] synonym: "mislocalised septum, near new end" EXACT [PomBase:mah] synonym: "mislocalised septum, near non-growing end" NARROW [PomBase:mah] synonym: "mislocalized septum, near new end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized septum, near new end, during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized septum, near non-growing end" NARROW [PomBase:mah] synonym: "mislocalized septum, near non-growing end, during vegetative growth" NARROW [PomBase:mah] synonym: "misplaced septum, near new end" EXACT [PomBase:vw] is_a: FYPO:0000339 ! mislocalized septum during vegetative growth is_a: FYPO:0001225 ! monoseptate created_by: midori creation_date: 2012-08-15T13:08:14Z [Term] id: FYPO:0001392 name: abnormal regulation of cell growth def: "A regulation phenotype in which regulation of vegetative cell growth is abnormal." [PomBase:mah] synonym: "abnormal regulation of vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-15T13:20:37Z [Term] id: FYPO:0001393 name: abnormal activation of monopolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, is abnormal." [PomBase:mah] synonym: "abnormal regulation of monopolar vegetative cell growth" RELATED [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-15T13:21:29Z [Term] id: FYPO:0001394 name: activation of monopolar cell growth at either end def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth may occur at either the new or old end of the cell, instead of exclusively at the old end, following cell division. A population of cells with this phenotype has a 1:1 mix of cells initiating growth at the new end and cells initiating growth at the old end." [PomBase:mah] synonym: "abnormal initiation of growth from either old or new end following cell division" EXACT [PomBase:al] synonym: "activation of monopolar vegetative cell growth at either end" EXACT [PomBase:mah] is_a: FYPO:0001393 ! abnormal activation of monopolar cell growth created_by: midori creation_date: 2012-08-15T13:23:28Z [Term] id: FYPO:0001395 name: normal activation of monopolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal activation of monopolar vegetative cell growth" EXACT [PomBase:mah] synonym: "normal initiation of growth from old end following cell division" EXACT [PomBase:al] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-15T13:35:02Z [Term] id: FYPO:0001396 name: normal NETO def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal activation of bipolar cell growth" RELATED [PomBase:mah] synonym: "normal cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "normal NETO during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal NETO during vegetative growth" EXACT [PomBase:mah] synonym: "normal new end take-off" EXACT [PomBase:mah] synonym: "normal switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-15T13:48:18Z [Term] id: FYPO:0001397 name: monopolar actin cortical patch localization to old end def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only the old end of a cell following cell division." [PomBase:mah] synonym: "decreased actin cortical patch localization at non-growing end" RELATED [PomBase:vw] synonym: "monopolar actin cortical patch localisation to old end" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch localization to old end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "monopolar actin cortical patch localization to old end during vegetative growth" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch location at old end" RELATED [PomBase:mah] synonym: "monopolar actin patch localization to old end" EXACT [PomBase:mah] synonym: "monopolar F-actin patch localization to old end" EXACT [PomBase:mah] synonym: "reduced actin patch localization to non-growing cell end" RELATED [PomBase:vw] is_a: FYPO:0001019 ! monopolar actin cortical patch localization during vegetative growth created_by: midori creation_date: 2012-08-15T14:00:14Z [Term] id: FYPO:0001398 name: monopolar actin cortical patch localization to either end def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only one end of a cell following cell division; patches may localize to either the old or the new end. A population of cells with this phenotype has a 1:1 mix of cells with actin patches at the old end and cells with patches at the new end." [PomBase:mah] synonym: "monopolar actin cortical patch localisation to either end" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch localization to either end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "monopolar actin cortical patch localization to either end during vegetative growth" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch location at either end" RELATED [PomBase:mah] synonym: "monopolar actin patch localization to either end" EXACT [PomBase:mah] synonym: "monopolar F-actin patch localization to either end" EXACT [PomBase:mah] is_a: FYPO:0001019 ! monopolar actin cortical patch localization during vegetative growth created_by: midori creation_date: 2012-08-15T14:06:42Z [Term] id: FYPO:0001399 name: normal mitotic spindle def: "A physical cellular phenotype in which the mitotic spindle is normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation." [PomBase:mah] synonym: "normal mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "normal spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth is_a: FYPO:0004568 ! normal spindle created_by: midori creation_date: 2012-08-15T14:29:30Z [Term] id: FYPO:0001400 name: normal interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "normal interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "normal interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001976 ! normal cytoplasmic microtubules during vegetative growth created_by: midori creation_date: 2012-08-15T14:40:33Z [Term] id: FYPO:0001401 name: abnormal protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell division site and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell division site" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein recruitment to cell division site" RELATED [PomBase:vw] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-08-15T15:14:14Z [Term] id: FYPO:0001402 name: normal protein localization to cell cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cell cortex during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2012-08-15T15:15:59Z [Term] id: FYPO:0001403 name: increased cell-substrate adhesion def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells adhere to a substrate more strongly or to a greater extent than normal." [PomBase:mah] synonym: "increased cell-substrate adhesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell-substrate adhesion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth created_by: midori creation_date: 2012-08-15T15:36:37Z [Term] id: FYPO:0001404 name: irregular colony morphology def: "A colony morphology phenotype in which the outline of a colony growing on a solid surface is not symmetrical." [PomBase:mah, PomBase:mp] synonym: "wavy-edged colony" RELATED [PomBase:vw] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2012-08-15T15:38:42Z [Term] id: FYPO:0001405 name: glossy colony morphology def: "A colony morphology phenotype in which a colony growing on a solid surface has an abnormally glossy surface." [PomBase:mah, PomBase:mp] synonym: "smooth colony morphology" RELATED [PomBase:vw] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2012-08-15T15:40:06Z [Term] id: FYPO:0001406 name: increased septum thickness def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is thicker than normal." [PomBase:mah] synonym: "increased septal material" RELATED [PomBase:vw] synonym: "increased septum thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased septum thickness during vegetative growth" EXACT [PomBase:mah] synonym: "thick septum" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2012-08-15T15:43:42Z [Term] id: FYPO:0001407 name: decreased cell population growth on glucose carbon source alt_id: FYPO:0001161 alt_id: FYPO:0001163 def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glucose as the carbon source." [PomBase:mah] comment: Note that this term encompasses growth under aerobic or semi-anaerobic conditions, whereas most cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased aerobic cell population growth on glucose carbon source" NARROW [PomBase:mah] synonym: "decreased growth on glucose carbon source" BROAD [PomBase:mah] synonym: "decreased hypoxic cell population growth on glucose carbon source" NARROW [PomBase:mah] synonym: "decreased vegetative cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on glucose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-08-16T15:53:30Z [Term] id: FYPO:0001408 name: sensitive to heat shock def: "A cell phenotype in which cells show increased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "decreased growth during cellular response to heat shock" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to heat shock" EXACT [PomBase:mah] synonym: "hypersensitive to heat shock" EXACT [PomBase:mah] synonym: "sensitive to heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to heat shock during vegetative growth" EXACT [PomBase:mah] synonym: "thermo-sensitive" RELATED [PomBase:vw] synonym: "thermosensitive" RELATED [PomBase:vw] is_a: FYPO:0000082 ! decreased cell population growth at high temperature created_by: midori creation_date: 2012-08-16T16:02:56Z [Term] id: FYPO:0001409 name: normal growth on glycerol carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glycerol as the carbon source." [PomBase:mah] synonym: "normal cell population growth on glycerol carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on glycerol carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-16T16:19:09Z [Term] id: FYPO:0001410 name: normal cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "normal cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "normal cellular sulfide ion level" EXACT [PomBase:mah] synonym: "normal cellular sulfide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular sulphide level" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-16T16:41:11Z [Term] id: FYPO:0001411 name: altered cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular sulfide level" EXACT [PomBase:mah] synonym: "altered cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "altered cellular sulfide ion level" EXACT [PomBase:mah] synonym: "altered cellular sulfide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular sulphide level" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-16T16:43:19Z [Term] id: FYPO:0001412 name: decreased cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "decreased cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "decreased cellular sulfide ion level" EXACT [PomBase:mah] synonym: "decreased cellular sulfide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular sulphide level" EXACT [PomBase:mah] synonym: "reduced cellular sulfide level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001411 ! altered cellular sulfide level created_by: midori creation_date: 2012-08-16T16:54:55Z [Term] id: FYPO:0001413 name: increased cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "increased cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "increased cellular sulfide ion level" EXACT [PomBase:mah] synonym: "increased cellular sulfide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular sulphide level" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001411 ! altered cellular sulfide level created_by: midori creation_date: 2012-08-16T16:56:12Z [Term] id: FYPO:0001414 name: sensitive to sulfide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sulfide (S2-). Cells stop growing (and may die) at a concentration of sulfide ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sulfide" EXACT [PomBase:mah] synonym: "sensitive to sulfide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sulfide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to sulfide ions" EXACT [PomBase:mah] synonym: "sensitive to sulphide" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-08-16T17:01:57Z [Term] id: FYPO:0001415 name: abnormal sulfide:quinone oxidoreductase activity def: "A molecular function phenotype in which the observed rate of sulfide:quinone oxidoreductase activity is abnormal." [PomBase:mah] synonym: "abnormal sulfide-quinone reductase activity" EXACT [GO:0070224] synonym: "abnormal sulfide:quinone reductase activity" EXACT [PomBase:al] synonym: "abnormal sulphide:quinone oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-16T17:02:48Z [Term] id: FYPO:0001416 name: decreased sulfide:quinone oxidoreductase activity def: "A molecular function phenotype in which the observed rate of sulfide:quinone oxidoreductase activity is decreased." [PomBase:mah] synonym: "decreased sulfide-quinone reductase activity" EXACT [GO:0070224] synonym: "decreased sulfide:quinone reductase activity" EXACT [PomBase:al] synonym: "decreased sulphide:quinone oxidoreductase activity" EXACT [PomBase:mah] synonym: "reduced sulfide:quinone oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001415 ! abnormal sulfide:quinone oxidoreductase activity created_by: midori creation_date: 2012-08-16T17:03:37Z [Term] id: FYPO:0001417 name: mislocalized eMTOC def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an equatorial microtubule organizing center in an abnormal location. The normal location is at the center of the cell." [PomBase:mah] synonym: "mislocalised eMTOC" EXACT [PomBase:mah] synonym: "mislocalized eMTOC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized eMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized equatorial microtubule organizing center" EXACT [GO:0000923] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2012-08-22T11:59:56Z [Term] id: FYPO:0001418 name: abnormal microtubule cytoskeleton morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. synonym: "abnormal microtubule cytoskeleton morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000352 ! abnormal cytoskeleton morphology during vegetative growth is_a: FYPO:0003064 ! abnormal microtubule cytoskeleton morphology created_by: midori creation_date: 2012-08-22T12:00:57Z [Term] id: FYPO:0001419 name: normal cell population growth rate def: "A cell population phenotype in which a population of cells grows at the same rate as wild type." [PomBase:mah] synonym: "normal cell population proliferation" RELATED [PomBase:vw] synonym: "normal cell proliferation" RELATED [PomBase:vw] synonym: "normal growth rate" BROAD [PomBase:mah] is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2012-08-22T13:05:17Z [Term] id: FYPO:0001420 name: normal vegetative cell population growth rate def: "A cell population phenotype in which a population of cells grow at the same rate as wild type in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal growth rate" BROAD [PomBase:mah] synonym: "normal vegetative cell population proliferation" RELATED [PomBase:vw] synonym: "normal vegetative cell proliferation" RELATED [PomBase:vw] is_a: FYPO:0001419 ! normal cell population growth rate is_a: FYPO:0002060 ! viable vegetative cell population created_by: midori creation_date: 2012-08-22T13:07:40Z [Term] id: FYPO:0001421 name: abnormal protein processing during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein processing is abnormal. Protein processing is the cleavage of one or more bonds within a protein that leads to the formation of mature, fully functional protein." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein cleavage during vegetative growth" RELATED [PomBase:vw] synonym: "abnormal protein maturation by peptide bond cleavage during vegetative growth" EXACT [GO:0016485] synonym: "abnormal protein maturation by peptide bond hydrolysis during vegetative growth" EXACT [GO:0016485] synonym: "abnormal protein processing during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000328 ! abnormal protein metabolic process during vegetative growth is_a: FYPO:0006374 ! abnormal protein processing created_by: midori creation_date: 2012-08-22T13:47:53Z [Term] id: FYPO:0001422 name: decreased protein processing during vegetative growth def: "A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the observed occurrence of protein processing is decreased." [PMID:19520858, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein cleavage during vegetative growth" RELATED [PomBase:vw] synonym: "decreased protein maturation by peptide bond cleavage during vegetative growth" EXACT [GO:0016485] synonym: "decreased protein maturation by peptide bond hydrolysis during vegetative growth" EXACT [GO:0016485] synonym: "decreased protein processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Sre1 cleavage" NARROW [PomBase:mah] synonym: "reduced protein processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001421 ! abnormal protein processing during vegetative growth created_by: midori creation_date: 2012-08-22T14:19:01Z [Term] id: FYPO:0001423 name: normal protein targeting to vacuole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein targeting to vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein targeting to vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar protein sorting" EXACT [PomBase:mah] is_a: FYPO:0000601 ! normal vacuolar transport created_by: midori creation_date: 2012-08-22T14:28:30Z [Term] id: FYPO:0001424 name: abolished protein localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear exclusion during vegetative growth" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during vegetative growth" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth is_a: FYPO:0003450 ! abolished protein localization to nucleus created_by: midori creation_date: 2012-08-22T14:54:11Z [Term] id: FYPO:0001425 name: abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome." [PMID:10388806, PomBase:mah] comment: Consider also annotating to 'abnormal mitosis' (FYPO:0000337), 'inviable swollen elongated cell with enlarged nucleus' (FYPO:0002083), or both. If a cell undergoes several rounds of complete rereplication, the FYPO:0002083 phenotype usually results. synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth, resulting in complete rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in complete re-replication" EXACT [PomBase:mah] synonym: "complete mitotic DNA re-replication" RELATED [PomBase:mah] synonym: "complete mitotic DNA rereplication" RELATED [PomBase:mah] synonym: "endoreduplication" RELATED [PomBase:mah] synonym: "endoreplication" RELATED [PomBase:mah] synonym: "increased spontaneous diploidization" RELATED [PomBase:vw] is_a: FYPO:0000216 ! abnormal negative regulation of mitotic DNA replication initiation relationship: has_output FYPO:0000158 ! DNA content increased during vegetative growth created_by: midori creation_date: 2012-08-22T15:01:52Z [Term] id: FYPO:0001426 name: abnormal negative regulation of mitotic DNA replication initiation resulting in partial rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in rereplication of part of the genome." [PMID:10388806, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth, resulting in partial rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in partial rereplication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in partial re-replication" EXACT [PomBase:mah] synonym: "partial mitotic DNA re-replication" RELATED [PomBase:mah] synonym: "partial mitotic DNA rereplication" RELATED [PomBase:mah] synonym: "replication origin refiring resulting in local amplification" RELATED [PMID:20736315, PomBase:al] is_a: FYPO:0000216 ! abnormal negative regulation of mitotic DNA replication initiation relationship: has_output FYPO:0000158 ! DNA content increased during vegetative growth created_by: midori creation_date: 2012-08-22T15:05:13Z [Term] id: FYPO:0001427 name: abnormal negative regulation of mitotic DNA replication initiation resulting in slow rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in a single round of rereplication of the entire genome, which takes place more slowly than normal replication." [PMID:10388806, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth, resulting in slow rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in slow rereplication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in slow re-replication" EXACT [PomBase:mah] synonym: "slow mitotic DNA re-replication" RELATED [PomBase:mah] synonym: "slow mitotic DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0000216 ! abnormal negative regulation of mitotic DNA replication initiation relationship: has_output FYPO:0000158 ! DNA content increased during vegetative growth created_by: midori creation_date: 2012-08-22T15:06:50Z [Term] id: FYPO:0001428 name: normal negative regulation of mitotic DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal negative regulation of DNA replication initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal negative regulation of DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal negative regulation of initiation of DNA replication initiation" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-08-22T15:08:32Z [Term] id: FYPO:0001429 name: swollen elongated cell def: "A cell morphology phenotype in which a cell has a larger volume, greater length, greater diameter, and greater length:diameter ratio than normal." [PMID:10388806, PomBase:mah] comment: The distinction between this phenotype and centrally constricted (dumbbell-shaped) cells (FYPO:0000779) is that swollen elongated cells do not have a constriction along the long axis. Swollen elongated cells may have a uniform diameter, or may be swollen only around the nucleus. synonym: "elongated cell with increased cell volume" EXACT [PomBase:mah] synonym: "enlarged elongated cell" RELATED [PomBase:mah] synonym: "large elongated cell" RELATED [PomBase:vw] is_a: FYPO:0000025 ! swollen cell is_a: FYPO:0006633 ! increased cell length created_by: midori creation_date: 2012-08-22T15:16:12Z [Term] id: FYPO:0001430 name: abnormal mitotic cell cycle arrest with unreplicated DNA def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested before cells have replicated genomic DNA, under conditions where arrest does not normally occur." [PomBase:mah] comment: Arrest with unreplicated DNA may occur between mitosis and the beginning of S phase; if only DNA content is measured, the arrest point cannot be determined with greater precision. synonym: "abnormal cell cycle arrest with unreplicated DNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with 1C DNA content" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with unreplicated DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression relationship: has_output FYPO:0001974 ! increased number of cells with 1C DNA content created_by: midori creation_date: 2012-08-22T15:27:17Z [Term] id: FYPO:0001431 name: resistance to Dio-9 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of the antibiotic Dio-9 than normal." [PomBase:mah] comment: DIO 9 has CAS registry number 11006-20-5. synonym: "resistance to DIO 9" EXACT [PomBase:mah] synonym: "resistance to Dio-9 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to Dio-9 during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to Dio-9" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-23T12:22:31Z [Term] id: FYPO:0001432 name: resistance to ethidium bromide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethidium bromide than normal." [PomBase:mah] synonym: "resistance to EtBr" EXACT [PomBase:mah] synonym: "resistance to ethidium bromide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to ethidium bromide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to ethidium bromide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-23T12:45:11Z [Term] id: FYPO:0001433 name: resistance to decamethylenediguanidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of decamethylenediguanidine than normal." [PomBase:mah] synonym: "resistance to Anticoman" EXACT [CHEBI:768260, PomBase:mah] synonym: "resistance to decamethylenediguanidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to decamethylenediguanidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to decamethylenediguanidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-23T12:49:28Z [Term] id: FYPO:0001434 name: resistance to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N,N'-(p-xylylidene)bis-aminoguanidine 2HCl than normal." [PomBase:mah] synonym: "resistance to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-23T12:50:30Z [Term] id: FYPO:0001435 name: normal growth on erythromycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing erythromycin." [PomBase:mah] synonym: "normal cell population growth in presence of erythromycin" EXACT [PomBase:mah] synonym: "normal cell population growth on erythromycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to erythromycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on erythromycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:53:50Z [Term] id: FYPO:0001436 name: normal growth on trichodermin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trichodermin." [PomBase:mah] synonym: "normal cell population growth in presence of trichodermin" EXACT [PomBase:mah] synonym: "normal cell population growth on trichodermin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to trichodermin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on trichodermin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:55:40Z [Term] id: FYPO:0001437 name: normal growth on antimycin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing antimycin A." [PomBase:mah] synonym: "normal cell population growth in presence of antimycin A" EXACT [PomBase:mah] synonym: "normal cell population growth on antimycin A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to antimycin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on antimycin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:56:12Z [Term] id: FYPO:0001438 name: normal growth on tetracycline def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tetracycline." [PomBase:mah] synonym: "normal cell population growth in presence of tetracycline" EXACT [PomBase:mah] synonym: "normal cell population growth on tetracycline" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to tetracycline" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tetracycline" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:58:33Z [Term] id: FYPO:0001439 name: normal growth on chloramphenicol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chloramphenicol." [PomBase:mah] synonym: "normal cell population growth in presence of chloramphenicol" EXACT [PomBase:mah] synonym: "normal cell population growth on chloramphenicol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to chloramphenicol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on chloramphenicol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:59:01Z [Term] id: FYPO:0001440 name: abnormal protein complex localization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal." [PomBase:mah] synonym: "abnormal cellular protein complex localization" EXACT [GO:0034629, PomBase:mah] synonym: "abnormal protein complex localisation" EXACT [GO:0034629, PomBase:mah] synonym: "abnormal protein complex localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein complex localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-08-23T14:24:05Z [Term] id: FYPO:0001441 name: decreased SAGA complex localization to promoter region def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the SAGA complex to chromatin at promoters is decreased." [PomBase:mah] synonym: "decreased SAGA complex localisation to promoter region" EXACT [PomBase:mah] synonym: "decreased SAGA complex localization to promoter region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased SAGA complex localization to promoter region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased SAGA complex localization to transcription regulatory region" EXACT [GO:0072742, PomBase:mah] synonym: "decreased SAGA complex recruitment" EXACT [GO:0072742, PomBase:mah] synonym: "reduced SAGA complex localization to promoter region" EXACT [PomBase:mah] synonym: "reduced SAGA complex recruitment" EXACT [PomBase:vw] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001440 ! abnormal protein complex localization created_by: midori creation_date: 2012-08-23T14:34:58Z [Term] id: FYPO:0001442 name: decreased histone H3-K9 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "decreased histone H3-K9 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone lysine H3 K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "reduced histone H3-K9 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000891 ! abnormal histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2012-08-23T14:45:03Z [Term] id: FYPO:0001443 name: abolished transcription during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription does not occur. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "abolished transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "transcription abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth is_a: FYPO:0002877 ! abolished transcription created_by: midori creation_date: 2012-08-23T14:53:02Z [Term] id: FYPO:0001444 name: increased cellular trehalose level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular trehalose level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased trehalose accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0002685 ! increased cellular trehalose level created_by: midori creation_date: 2012-08-23T15:18:12Z [Term] id: FYPO:0001445 name: increased cellular trehalose level during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal when the cell is subject to heat shock." [PomBase:mah] synonym: "increased cellular trehalose level during heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular trehalose level during vegetative growth and during heat shock" EXACT [PomBase:mah] synonym: "increased trehalose accumulation during heat shock" RELATED [PomBase:mah] is_a: FYPO:0001444 ! increased cellular trehalose level during vegetative growth created_by: midori creation_date: 2012-08-23T15:19:11Z [Term] id: FYPO:0001446 name: altered cellular trehalose level def: "A cell phenotype in which the amount of trehalose measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular trehalose accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular trehalose level" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-08-23T15:22:37Z [Term] id: FYPO:0001447 name: decreased cellular trehalose level def: "A cell phenotype in which the amount of trehalose measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular trehalose accumulation" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0001446 ! altered cellular trehalose level created_by: midori creation_date: 2012-08-23T15:24:19Z [Term] id: FYPO:0001448 name: trehalose absent from cell during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is too low to detect." [PomBase:mah] synonym: "absent trehalose" EXACT [PomBase:al] synonym: "trehalose absent from cell during heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "trehalose absent from cell during vegetative growth and during heat shock" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth is_a: FYPO:0001446 ! altered cellular trehalose level created_by: midori creation_date: 2012-08-23T15:26:41Z [Term] id: FYPO:0001449 name: normal cellular trehalose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular trehalose accumulation" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-23T15:28:23Z [Term] id: FYPO:0001450 name: resistance to cold def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to cold." [PomBase:mah] synonym: "increased growth during cellular response to cold" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to cold" EXACT [PomBase:mah] synonym: "resistance to cold during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cold during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to low temperature" EXACT [PomBase:mah] synonym: "resistant to cold" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2012-08-23T15:46:25Z [Term] id: FYPO:0001451 name: resistance to freezing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to freezing." [PomBase:mah] synonym: "increased growth during cellular response to freezing" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to freezing" EXACT [PomBase:mah] synonym: "resistance to freezing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to freezing during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to freeze-thawing" RELATED [PomBase:al] synonym: "resistant to freezing" EXACT [PomBase:mah] is_a: FYPO:0001450 ! resistance to cold created_by: midori creation_date: 2012-08-23T15:47:42Z [Term] id: FYPO:0001452 name: resistance to water deprivation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to water deprivation." [PomBase:mah] synonym: "increased growth during cellular response to water deprivation" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to water deprivation" EXACT [PomBase:mah] synonym: "resistance to water deprivation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to water deprivation during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to dehydration" EXACT [GO:0009414, PomBase:al] synonym: "resistant to water deprivation" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2012-08-23T15:49:03Z [Term] id: FYPO:0001453 name: resistance to ethanol def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethanol than normal." [PomBase:mah] synonym: "resistance to ethanol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to ethanol during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to ethyl alcohol" EXACT [CHEBI:16236] synonym: "resistant to ethanol" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-23T15:50:53Z [Term] id: FYPO:0001454 name: normal growth during cellular response to freezing def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to freezing conditions." [PomBase:mah] synonym: "normal cell population growth during cellular response to freezing" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to freeze-thawing" RELATED [PomBase:al] synonym: "normal cellular response to freezing" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to freezing" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T15:54:30Z [Term] id: FYPO:0001455 name: normal cellular response to water deprivation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to water deprivation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to dehydration" EXACT [GO:0009414, GO:0042631, PomBase:al] synonym: "normal cellular response to water deprivation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to water deprivation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-23T15:58:02Z [Term] id: FYPO:0001456 name: increased RNA level during cellular response to endoplasmic reticulum stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to endoplasmic reticulum stress is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to endoplasmic reticulum stress" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to endoplasmic reticulum stress" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to endoplasmic reticulum stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during response to ER stress" EXACT [GO:0034976, PomBase:mah] synonym: "increased RNA level under ER stress-inducing conditions" RELATED [PomBase:vw] synonym: "increased transcript level during cellular response to endoplasmic reticulum stress" EXACT [PomBase:vw] synonym: "increased unfolded protein response" RELATED [] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-08-23T16:26:07Z [Term] id: FYPO:0001457 name: sensitive to tunicamycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tunicamycin. Cells stop growing (and may die) at a concentration of tunicamycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tunicamycin" EXACT [PomBase:mah] synonym: "sensitive to tunicamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tunicamycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-08-23T16:33:02Z [Term] id: FYPO:0001458 name: decreased histone H3-K14 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K14 acetylation during vegetative growth" EXACT [GO:0044154, PomBase:mah] synonym: "decreased histone H3-K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone lysine H3 K14 acetylation during vegetative growth" EXACT [GO:0044154, PomBase:mah] synonym: "reduced histone H3-K14 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000788 ! abnormal histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2012-08-24T14:22:25Z [Term] id: FYPO:0001459 name: obsolete increased basal transcription from CDRE promoter def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the level of transcription from a calcineurin-dependent response element (CDRE)-containing promoter is higher than normal in the absence of a calcium ion stimulus." [PMID:21811607, PomBase:mah] comment: This term was made obsolete because it did not define "basal" transcription sufficiently precisely. synonym: "increased basal transcription from CDRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased basal transcription from CDRE promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription from CRDE promoter in the absence of calcium" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2012-08-29T14:03:47Z [Term] id: FYPO:0001460 name: increased transcription from CDRE promoter in response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is increased following a calcium ion stimulus." [PMID:21811607, PomBase:mah] synonym: "increased transcription from CDRE promoter in response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from CDRE promoter in response to calcium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2012-08-29T14:14:33Z [Term] id: FYPO:0001461 name: normal immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases normally immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "normal immediate intracellular calcium spike following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001199 ! normal cellular calcium level created_by: midori creation_date: 2012-08-29T14:47:54Z [Term] id: FYPO:0001462 name: altered cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular calcium accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular calcium level" EXACT [PomBase:mah] synonym: "altered cellular calcium ion level" EXACT [PomBase:mah] synonym: "altered cellular calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered cellular calcium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-29T14:51:00Z [Term] id: FYPO:0001463 name: abnormal immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "abnormal immediate intracellular calcium spike following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-08-29T14:59:29Z [Term] id: FYPO:0001464 name: obsolete increased immediate intracellular calcium spike following extracellular calcium stimulus def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases to a greater extent than normal immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] comment: This term was made obsolete because it does not accurately describe an observed phenotype. synonym: "increased immediate intracellular calcium spike following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-08-29T15:00:24Z [Term] id: FYPO:0001465 name: decreased immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases to a lesser extent than normal immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "decreased immediate intracellular calcium spike following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced immediate intracellular calcium spike following extracellular calcium stimulus" EXACT [PomBase:mah] is_a: FYPO:0001463 ! abnormal immediate intracellular calcium spike following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:03:36Z [Term] id: FYPO:0001466 name: abolished immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration does not increase immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "abolished immediate intracellular calcium spike following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "immediate intracellular calcium spike following extracellular calcium stimulus abolished" EXACT [PomBase:mah] synonym: "immediate intracellular calcium spike following extracellular calcium stimulus abolished during vegetative growth" EXACT [PomBase:mah] synonym: "immediate intracellular calcium spike following extracellular calcium stimulus absent" EXACT [PomBase:mah] is_a: FYPO:0001463 ! abnormal immediate intracellular calcium spike following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:32:06Z [Term] id: FYPO:0001467 name: obsolete normal increase in steady-state intracellular calcium level following extracellular calcium stimulus def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases normally following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours." [PMID:21811607, PomBase:mah] comment: This term was made obsolete because it does not accurately describe an observed phenotype. synonym: "normal increase in steady-state intracellular calcium level following extracellular calcium stimulus" EXACT [PomBase:mah] synonym: "normal increase in steady-state intracellular calcium level following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-08-29T15:52:34Z [Term] id: FYPO:0001468 name: abnormal steady-state intracellular calcium level following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases abnormally, or does not change, following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours." [PMID:21811607, PomBase:mah] synonym: "abnormal increase in steady-state intracellular calcium level following extracellular calcium stimulus" EXACT [PomBase:mah] synonym: "abnormal increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal steady-state intracellular calcium level following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-08-29T15:54:22Z [Term] id: FYPO:0001469 name: increased steady-state intracellular calcium level following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases to a greater extent than normal following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours." [PMID:21811607, PomBase:mah] synonym: "greater increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] synonym: "increased steady-state intracellular calcium level following extracellular calcium stimulus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001468 ! abnormal steady-state intracellular calcium level following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:55:25Z [Term] id: FYPO:0001470 name: normal growth on tacrolimus def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus." [PomBase:mah] synonym: "normal cell population growth in presence of tacrolimus" EXACT [PomBase:mah] synonym: "normal cell population growth on tacrolimus" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to FK506" EXACT [CHEBI:61057] synonym: "normal cellular response to tacrolimus" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tacrolimus" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-29T16:03:18Z [Term] id: FYPO:0001471 name: normal growth on tacrolimus during salt stress def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus, when the cell is subject to salt stress." [PomBase:mah] synonym: "normal cell population growth in presence of tacrolimus during salt stress" EXACT [PomBase:mah] synonym: "normal cell population growth on FK506 during salt stress" EXACT [CHEBI:61057] synonym: "normal cell population growth on tacrolimus during salt stress" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to salt stress and tacrolimus" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus and salt stress" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus during salt stress" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tacrolimus during salt stress" EXACT [PomBase:mah] is_a: FYPO:0001037 ! normal growth during cellular response to salt stress is_a: FYPO:0001470 ! normal growth on tacrolimus created_by: midori creation_date: 2012-08-29T16:04:35Z [Term] id: FYPO:0001472 name: normal growth on tacrolimus during osmotic stress def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus during a cellular response to osmotic stress." [PomBase:mah] synonym: "normal cell population growth in presence of tacrolimus during osmotic stress" EXACT [PomBase:mah] synonym: "normal cell population growth on tacrolimus and sorbitol" NARROW [PomBase:al] synonym: "normal cell population growth on tacrolimus during osmotic stress" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to FK506 during osmotic stress" EXACT [CHEBI:61057] synonym: "normal cellular response to tacrolimus and osmotic stress" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus and sorbitol" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus during osmotic stress" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tacrolimus during osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001021 ! normal growth during cellular response to osmotic stress is_a: FYPO:0001470 ! normal growth on tacrolimus created_by: midori creation_date: 2012-08-29T16:08:07Z [Term] id: FYPO:0001473 name: resistance to tacrolimus during salt stress def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tacrolimus than normal when the cells are subject to salt stress." [PomBase:mah] synonym: "resistance to FK506 during salt stress" EXACT [CHEBI:61057, PomBase:mah] synonym: "resistance to salt stress and tacrolimus" EXACT [PomBase:al] synonym: "resistance to tacrolimus and salt stress" EXACT [PomBase:al] synonym: "resistance to tacrolimus during salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tacrolimus during salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tacrolimus during salt stress" EXACT [PomBase:mah] is_a: FYPO:0001379 ! resistance to tacrolimus created_by: midori creation_date: 2012-08-29T16:11:06Z [Term] id: FYPO:0001474 name: abnormal mitotic spindle pole body morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitotic spindle pole body is abnormal." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "abnormal mitotic SPB morphology" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body structure" NARROW [PomBase:mah] synonym: "abnormal spindle pole body morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle pole body morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0004607 ! abnormal spindle pole body morphology created_by: midori creation_date: 2012-08-29T16:52:01Z [Term] id: FYPO:0001475 name: fragmented mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body is broken into fragments." [PomBase:mah] synonym: "fragmented mitotic SPB" EXACT [PomBase:mah] synonym: "fragmented spindle pole body during mitotic cell cycle" EXACT [PomBase:mah] synonym: "fragmented spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle pole body fragmentation" EXACT [PomBase:vw] is_a: FYPO:0001474 ! abnormal mitotic spindle pole body morphology is_a: FYPO:0006404 ! fragmented spindle pole body created_by: midori creation_date: 2012-08-29T16:52:11Z [Term] id: FYPO:0001476 name: abnormal guanosine-diphosphatase activity def: "A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is abnormal." [PomBase:mah] synonym: "abnormal GDPase activity" EXACT [GO:0004382, PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-30T11:37:58Z [Term] id: FYPO:0001477 name: decreased guanosine-diphosphatase activity def: "A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is decreased." [PomBase:mah] synonym: "decreased GDPase activity" EXACT [GO:0004382, PomBase:mah] synonym: "reduced guanosine-diphosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001476 ! abnormal guanosine-diphosphatase activity created_by: midori creation_date: 2012-08-30T11:38:10Z [Term] id: FYPO:0001478 name: increased guanosine-diphosphatase activity def: "A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is increased." [PomBase:mah] synonym: "increased GDPase activity" EXACT [GO:0004382, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001476 ! abnormal guanosine-diphosphatase activity created_by: midori creation_date: 2012-08-30T11:38:17Z [Term] id: FYPO:0001479 name: abnormal alpha,alpha-trehalase activity def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is abnormal." [PomBase:mah] synonym: "abnormal neutral trehalase activity" EXACT [PMID:9729425, PomBase:mah] synonym: "abnormal trehalase activity" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-30T11:47:38Z [Term] id: FYPO:0001480 name: normal alpha,alpha-trehalase activity def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal neutral trehalase activity" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-08-30T12:05:18Z [Term] id: FYPO:0001481 name: alpha,alpha-trehalase activity increase abolished during cellular response to nutrient def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a nutrient stimulus." [PomBase:mah] synonym: "absent increase in trehalase activity following nutrient stimulus" EXACT [PomBase:al] synonym: "neutral trehalase activity increase abolished during cellular response to nutrient" EXACT [PMID:9729425, PomBase:mah] synonym: "trehalase activity increase abolished during cellular response to nutrient" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity is_a: FYPO:0001484 ! abnormal cellular response to nutrient created_by: midori creation_date: 2012-08-30T12:11:19Z [Term] id: FYPO:0001482 name: alpha,alpha-trehalase activity increase abolished during cellular response to heat def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a heat stimulus." [PomBase:mah] synonym: "absent increase in trehalase activity in response to high temperature" EXACT [PomBase:al] synonym: "neutral trehalase activity increase abolished during cellular response to heat" EXACT [PMID:9729425, PomBase:mah] synonym: "trehalase activity increase abolished during cellular response to heat" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0000212 ! abnormal cellular response to heat is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2012-08-30T12:15:03Z [Term] id: FYPO:0001483 name: normal alpha,alpha-trehalase activity increase during cellular response to oxidative stress def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of oxidative stress." [PomBase:mah] synonym: "normal alpha,alpha-trehalase activity increase during oxidative stress response" EXACT [PomBase:vw] synonym: "normal increase in trehalase activity in response to oxidative stress" EXACT [PomBase:al] synonym: "normal neutral trehalase activity increase during cellular response to oxidative stress" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity increase during cellular response to oxidative stress" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001480 ! normal alpha,alpha-trehalase activity is_a: FYPO:0001485 ! normal cellular response to oxidative stress created_by: midori creation_date: 2012-08-30T12:18:52Z [Term] id: FYPO:0001484 name: abnormal cellular response to nutrient def: "A chemical response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a nutrient is abnormal." [PomBase:mah] synonym: "abnormal cellular response to nutrient during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to nutrient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2012-08-30T13:01:53Z [Term] id: FYPO:0001485 name: normal cellular response to oxidative stress def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to oxidative stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal oxidative stress response" EXACT [PomBase:vw] is_a: FYPO:0000968 ! normal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-30T13:03:23Z [Term] id: FYPO:0001486 name: normal RNA level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to salt stress" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-08-30T13:08:09Z [Term] id: FYPO:0001487 name: normal RNA level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to heat" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to high temperature" EXACT [PomBase:al] synonym: "normal transcript level during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-08-30T13:09:03Z [Term] id: FYPO:0001488 name: sensitive to protamine sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to protamine sulfate. A protamine is any of a group of simple proteins that yield basic amino acids on hydrolysis, and forms a complex with heparin. Cells stop growing (and may die) at a concentration of protamine sulfate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to protamine sulfate" EXACT [PomBase:mah] synonym: "sensitive to protamine sulfate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to protamine sulfate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to protamine sulphate" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-08-30T13:32:12Z [Term] id: FYPO:0001489 name: inviable vegetative cell def: "A cell phenotype in which a cell is inviable in the phase of the life cycle during which wild type cells undergo vegetative growth." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal in vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-08-30T13:59:02Z [Term] id: FYPO:0001490 name: inviable elongated vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable and longer than normal, and has a greater length:diameter ratio than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2012-08-30T14:08:27Z [Term] id: FYPO:0001491 name: viable vegetative cell def: "A cell phenotype in which a vegetatively growing cell is viable." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2012-08-30T14:12:48Z [Term] id: FYPO:0001492 name: viable elongated vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable and longer than normal, and has a greater length:diameter ratio than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated viable vegetative cell" EXACT [PomBase:mah] synonym: "viable elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2012-08-30T14:17:56Z [Term] id: FYPO:0001493 name: inviable elongated multinucleate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, is elongated, and contains more than one nucleus apiece." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate inviable vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated multinucleate vegetative cell" EXACT [PomBase:mah] synonym: "SIN phenotype" RELATED [PomBase:vw] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0001490 ! inviable elongated vegetative cell created_by: midori creation_date: 2012-08-30T14:27:16Z [Term] id: FYPO:0001494 name: inviable elongated multiseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, is elongated, and contains more than one septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multiseptate inviable vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated multiseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology created_by: midori creation_date: 2012-08-30T14:30:53Z [Term] id: FYPO:0001495 name: viable elongated multinucleate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable, is elongated, and contains more than one nucleus." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated multinucleate viable cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate viable vegetative cell" EXACT [PomBase:mah] synonym: "viable elongated multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0001492 ! viable elongated vegetative cell created_by: midori creation_date: 2012-08-30T14:32:23Z [Term] id: FYPO:0001496 name: viable elongated multiseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable, is elongated, and contain more than one septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated multiseptate viable vegetative cell" EXACT [PomBase:mah] synonym: "elongated viable multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable elongated multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0001492 ! viable elongated vegetative cell created_by: midori creation_date: 2012-08-30T14:32:53Z [Term] id: FYPO:0001497 name: inviable elongated cell with mitotic cell cycle arrest in interphase def: "A cell morphology phenotype in which a vegetative cell is inviable and elongated, and progression through the mitotic cell cycle is arrested in interphase. The cell contains one nucleus and no septum." [PomBase:mah] comment: A population of cells with this phenotype usually shows a marginal increase in cell number before all cells die. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell with mitotic cell cycle arrest in interphase during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell with mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic interphase" EXACT [PomBase:vw] synonym: "inviable elongated vegetative cell with cell cycle arrest in interphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with mitotic interphase arrest" EXACT [PomBase:vw] synonym: "lethal; elongated vegetative cell with mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in interphase with elongated inviable cell" EXACT [PomBase:vw] synonym: "mitotic interphase arrested elongated inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase is_a: FYPO:0001490 ! inviable elongated vegetative cell relationship: has_part FYPO:0000837 ! cell cycle arrest in mitotic interphase created_by: midori creation_date: 2012-08-30T14:37:31Z [Term] id: FYPO:0001498 name: sensitive to cytochalasin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cytochalasin B. Cells stop growing (and may die) at a concentration of cytochalasin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cytochalasin B" EXACT [PomBase:mah] synonym: "sensitive to cytochalasin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cytochalasin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-08-30T15:23:47Z [Term] id: FYPO:0001499 name: resistance to cytochalasin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cytochalasin B than normal." [PomBase:mah] synonym: "resistance to cytochalasin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cytochalasin B during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to cytochalasin B" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-08-30T15:24:42Z [Term] id: FYPO:0001500 name: normal growth on cytochalasin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cytochalasin B." [PomBase:mah] synonym: "normal cell population growth in presence of cytochalasin B" EXACT [PomBase:mah] synonym: "normal cell population growth on cytochalasin B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cytochalasin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cytochalasin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-30T15:25:41Z [Term] id: FYPO:0001501 name: sensitive to brefeldin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to brefeldin A. Cells stop growing (and may die) at a concentration of brefeldin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to brefeldin A" EXACT [PomBase:mah] synonym: "sensitive to BFA" EXACT [PomBase:mah] synonym: "sensitive to brefeldin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to brefeldin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-08-30T15:29:30Z [Term] id: FYPO:0001502 name: increased cellular trehalose level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal during a cellular response to osmotic stress." [PomBase:mah] synonym: "increased cellular trehalose level during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular trehalose level during vegetative growth and during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "increased cellular trehalose level in response to osmotic stress" EXACT [PomBase:al] synonym: "increased trehalose accumulation during cellular response to osmotic stress" RELATED [PomBase:mah] is_a: FYPO:0001444 ! increased cellular trehalose level during vegetative growth created_by: midori creation_date: 2012-08-31T14:27:51Z [Term] id: FYPO:0001503 name: decreased alpha,alpha-trehalase activity during sporulation def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during sporulation." [PomBase:mah] synonym: "decreased neutral trehalase activity during sporulation" EXACT [PMID:9729425, PomBase:mah] synonym: "decreased trehalase activity during sporulation" BROAD [GO:0004555, GO:0015927] synonym: "reduced alpha,alpha-trehalase activity during sporulation" EXACT [PomBase:mah] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2012-08-31T14:29:44Z [Term] id: FYPO:0001504 name: decreased cellular trehalose level during sporulation def: "A cell phenotype in which the amount of trehalose measured in a cell is lower than normal during sporulation." [PomBase:mah] synonym: "decreased cellular trehalose accumulation during sporulation" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level during sporulation" EXACT [PomBase:mah] is_a: FYPO:0001447 ! decreased cellular trehalose level created_by: midori creation_date: 2012-08-31T14:31:44Z [Term] id: FYPO:0001505 name: increased cellular phosphatidylserine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phosphatidyl-L-serine level" EXACT [CHEBI:18303] synonym: "increased cellular phosphatidylserine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphatidylserine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PS level" EXACT [PomBase:mah] synonym: "increased phosphatidylserine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-31T14:45:54Z [Term] id: FYPO:0001506 name: normal cellular phosphatidylcholine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylcholine measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular PC level" EXACT [PomBase:mah] synonym: "normal cellular phosphatidylcholine accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylcholine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylcholine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-31T14:48:33Z [Term] id: FYPO:0001507 name: normal cellular phosphatidylinositol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular phosphatidylinositol accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylinositol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylinositol level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular PI level" EXACT [CHEBI:28874, PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-31T14:49:23Z [Term] id: FYPO:0001508 name: abolished protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to chromatin during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2012-09-04T17:02:28Z [Term] id: FYPO:0001509 name: normal protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0006163 ! normal protein localization to chromatin created_by: midori creation_date: 2012-09-04T17:04:49Z [Term] id: FYPO:0001510 name: viable vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype in which a cell is viable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable lumpy cell" RELATED [PomBase:vw] synonym: "viable vegetative cell with abnormal cell shape and normal cell size" RELATED [PomBase:mah] synonym: "viable vegetative cell, abnormal cell shape, normal cell length" NARROW [PomBase:mah] synonym: "viable vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable, abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001121 ! vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0002176 ! viable vegetative cell with normal cell size is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape created_by: midori creation_date: 2012-09-13T10:47:20Z [Term] id: FYPO:0001511 name: inviable vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype in which a cell is inviable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable lumpy cell" RELATED [PomBase:vw] synonym: "inviable vegetative cell with abnormal cell shape and normal cell size" RELATED [PomBase:mah] synonym: "inviable vegetative cell, abnormal cell shape, normal cell length" NARROW [PomBase:mah] synonym: "inviable vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable, abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] synonym: "lethal; vegetative cell, abnormal cell shape, normal cell size" EXACT [PomBase:mah] is_a: FYPO:0001121 ! vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape created_by: midori creation_date: 2012-09-13T10:52:33Z [Term] id: FYPO:0001512 name: branched, elongated cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched and elongated." [PomBase:mah] comment: These cells often form a branch at a non-right angle to the long axis of the mother cell. synonym: "branched, elongated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, elongated vegetative cell" EXACT [PomBase:mah] synonym: "branched, long cell" EXACT [PomBase:vw] is_a: FYPO:0000015 ! branched vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000015 ! branched vegetative cell relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2012-09-13T10:58:38Z [Term] id: FYPO:0001513 name: normal mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid segregation is the entire process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle." [GO:0000070, PomBase:mah] synonym: "normal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid disjunction" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid segregation during vegetative growth" EXACT [PomBase:mah] synonym: "normal sister chromatid segregation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-09-13T11:23:11Z [Term] id: FYPO:0001514 name: decreased protein localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during vegetative growth" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth is_a: FYPO:0004455 ! decreased protein localization to nucleus created_by: midori creation_date: 2012-09-13T11:39:44Z [Term] id: FYPO:0001515 name: abnormal telomere tethering at nuclear periphery during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is abnormal." [PomBase:mah] synonym: "abnormal mitotic telomere tethering at nuclear periphery during vegetative growth" EXACT [GO:0044820] synonym: "abnormal telomere anchoring at nuclear periphery during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal telomere tethering at nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal telomere tethering to NE during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0007418 ! abnormal telomere localization to nuclear periphery is_a: FYPO:0008382 ! abnormal chromosome region phenotype during vegetative growth created_by: midori creation_date: 2012-09-13T11:46:25Z [Term] id: FYPO:0001516 name: resistance to mercury def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of mercury ions than normal." [PomBase:mah] synonym: "resistance to mercury during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to mercury during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to mercury ion" EXACT [PomBase:mah] synonym: "resistance to mercury ions" EXACT [PomBase:mah] synonym: "resistant to mercury" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-09-13T13:16:13Z [Term] id: FYPO:0001517 name: resistance to aluminium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aluminium ions than normal." [PomBase:mah] synonym: "resistance to aluminium cation" EXACT [CHEBI:63062] synonym: "resistance to aluminium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to aluminium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to aluminium ions" EXACT [PomBase:mah] synonym: "resistance to aluminum" EXACT [PomBase:mah] synonym: "resistant to aluminium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-09-13T13:22:53Z [Term] id: FYPO:0001518 name: resistance to diethyl maleate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of diethyl maleate than normal." [PomBase:mah] comment: Note that diethyl maleate should not be written without a space, as diethylmaleate is a different compound. synonym: "resistance to DEM" EXACT [PomBase:al] synonym: "resistance to diethyl maleate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to diethyl maleate during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to diethyl maleate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-09-13T13:41:57Z [Term] id: FYPO:0001519 name: obsolete abnormal gamma-glutamyltransferase activity def: "OBSOLETE. A molecular function phenotype in which the observed rate of gamma-glutamyltransferase activity is abnormal." [PomBase:mah] comment: This term was made obsolete because the GO term it cross-references has become obsolete. synonym: "abnormal gamma-glutamyl transpeptidase activity" EXACT [GO:0003840, PomBase:mah] synonym: "abnormal GGT activity" BROAD [PomBase:al, PomBase:mah] is_obsolete: true replaced_by: FYPO:0006089 created_by: midori creation_date: 2012-09-13T13:53:10Z [Term] id: FYPO:0001520 name: obsolete increased gamma-glutamyltransferase activity def: "OBSOLETE. A molecular function phenotype in which the observed rate of gamma-glutamyltransferase activity is increased." [PomBase:mah] comment: This term was made obsolete because the GO term it cross-references has become obsolete. synonym: "increased gamma-glutamyl transpeptidase activity" EXACT [GO:0003840, PomBase:mah] synonym: "increased GGT activity" BROAD [PomBase:al, PomBase:mah] is_obsolete: true replaced_by: FYPO:0006090 created_by: midori creation_date: 2012-09-13T13:53:17Z [Term] id: FYPO:0001521 name: increased cellular glutathione level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutathione level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular GSH level during vegetative growth" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular L-gamma-glutamyl-L-cysteinylglycine level during vegetative growth" EXACT [CHEBI:16856] synonym: "increased cellular reduced glutathione level during vegetative growth" EXACT [CHEBI:16856, PomBase:al] synonym: "increased glutathione accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T14:02:16Z [Term] id: FYPO:0001522 name: normal growth on caffeine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing caffeine." [PomBase:mah] synonym: "normal cell population growth in presence of caffeine" EXACT [PomBase:mah] synonym: "normal cell population growth on caffeine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to caffeine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on caffeine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-13T14:06:29Z [Term] id: FYPO:0001523 name: normal growth on leptomycin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing leptomycin B." [PomBase:mah] synonym: "normal cell population growth in presence of leptomycin B" EXACT [PomBase:mah] synonym: "normal cell population growth on leptomycin B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to leptomycin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on leptomycin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-13T14:09:56Z [Term] id: FYPO:0001524 name: resistance to L-thialysine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-thialysine than normal." [PomBase:mah] synonym: "resistance to L-thialysine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to L-thialysine during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to thialysine" BROAD [PomBase:mah] synonym: "resistant to L-thialysine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-09-13T14:36:42Z [Term] id: FYPO:0001525 name: sensitive to L-thialysine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-thialysine. Cells stop growing (and may die) at a concentration of L-thialysine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to L-thialysine" EXACT [PomBase:mah] synonym: "sensitive to L-thialysine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to L-thialysine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to thialysine" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-09-13T14:43:00Z [Term] id: FYPO:0001526 name: normal growth on L-thialysine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing L-thialysine." [PomBase:mah] synonym: "normal cell population growth in presence of L-thialysine" EXACT [PomBase:mah] synonym: "normal cell population growth on L-thialysine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on thialysine" BROAD [PomBase:mah] synonym: "normal cellular response to L-thialysine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on L-thialysine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-13T14:46:44Z [Term] id: FYPO:0001527 name: normal GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-09-13T14:53:26Z [Term] id: FYPO:0001528 name: abnormal GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GTP differently from wild type, or that a mutation in one gene affects GTP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-09-13T14:54:29Z [Term] id: FYPO:0001529 name: decreased GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GTP less than wild type, or that a mutation in one gene decreases GTP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "reduced GTP binding" EXACT [PomBase:mah] is_a: FYPO:0001528 ! abnormal GTP binding created_by: midori creation_date: 2012-09-13T14:55:25Z [Term] id: FYPO:0001530 name: abnormal GTPase activity def: "A molecular function phenotype in which the observed rate of GTPase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-09-13T15:01:53Z [Term] id: FYPO:0001531 name: decreased GTPase activity def: "A molecular function phenotype in which the observed rate of GTPase activity is decreased." [PomBase:mah] synonym: "reduced GTPase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001530 ! abnormal GTPase activity created_by: midori creation_date: 2012-09-13T15:02:01Z [Term] id: FYPO:0001532 name: normal duration of mitotic S phase def: "A cell cycle phenotype in which the duration of S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0003246 ! normal mitotic S phase progression created_by: midori creation_date: 2012-09-13T15:28:30Z [Term] id: FYPO:0001533 name: sensitive to zinc starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zinc starvation." [PomBase:mah] synonym: "decreased growth during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "hypersensitive to zinc starvation" EXACT [PomBase:mah] synonym: "sensitive to zinc depletion" EXACT [PomBase:vw] synonym: "sensitive to zinc deprivation" EXACT [PomBase:vw] synonym: "sensitive to zinc ion starvation" EXACT [PomBase:mah] synonym: "sensitive to zinc starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to zinc starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2012-09-13T15:35:17Z [Term] id: FYPO:0001534 name: decreased cellular zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular zinc ion level" EXACT [PomBase:mah] synonym: "decreased cellular zinc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular zinc level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased zinc accumulation" RELATED [PomBase:al] synonym: "reduced cellular zinc level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T15:43:51Z [Term] id: FYPO:0001535 name: normal cellular zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular zinc accumulation" RELATED [PomBase:mah] synonym: "normal cellular zinc ion level" EXACT [PomBase:mah] synonym: "normal cellular zinc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular zinc level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T15:48:08Z [Term] id: FYPO:0001536 name: normal cellular copper level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of copper ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular copper accumulation" RELATED [PomBase:mah] synonym: "normal cellular copper ion level" EXACT [PomBase:mah] synonym: "normal cellular copper level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular copper level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:07:14Z [Term] id: FYPO:0001537 name: normal cellular iron level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular iron accumulation" RELATED [PomBase:mah] synonym: "normal cellular iron ion level" EXACT [PomBase:mah] synonym: "normal cellular iron level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular iron level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:07:47Z [Term] id: FYPO:0001538 name: normal cellular potassium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of potassium ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular potassium accumulation" RELATED [PomBase:mah] synonym: "normal cellular potassium ion level" EXACT [PomBase:mah] synonym: "normal cellular potassium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular potassium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:08:23Z [Term] id: FYPO:0001539 name: normal cellular magnesium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of magnesium ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular magnesium accumulation" RELATED [PomBase:mah] synonym: "normal cellular magnesium ion level" EXACT [PomBase:mah] synonym: "normal cellular magnesium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular magnesium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:14:33Z [Term] id: FYPO:0001540 name: normal cellular manganese level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of manganese ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular manganese accumulation" RELATED [PomBase:mah] synonym: "normal cellular manganese ion level" EXACT [PomBase:mah] synonym: "normal cellular manganese level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular manganese level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:08:54Z [Term] id: FYPO:0001541 name: normal cellular molybdenum level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of molybdenum ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular molybdenum accumulation" RELATED [PomBase:mah] synonym: "normal cellular molybdenum ion level" EXACT [PomBase:mah] synonym: "normal cellular molybdenum level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular molybdenum level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:09:45Z [Term] id: FYPO:0001542 name: normal cellular nickel level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nickel ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular nickel accumulation" RELATED [PomBase:mah] synonym: "normal cellular nickel ion level" EXACT [PomBase:mah] synonym: "normal cellular nickel level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular nickel level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:10:13Z [Term] id: FYPO:0001543 name: normal cellular phosphorus level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphorus-containing substance measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular level of phosphorus-containing substance" EXACT [PomBase:mah] synonym: "normal cellular phosphorus accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphorus level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phosphorus level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:11:42Z [Term] id: FYPO:0001544 name: normal cellular sulfur level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfur measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular sulfur accumulation" RELATED [PomBase:mah] synonym: "normal cellular sulfur level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular sulfur level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular sulphur level" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:12:10Z [Term] id: FYPO:0001545 name: normal growth on L-canavanine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing L-canavanine." [PomBase:mah] synonym: "normal cell population growth in presence of L-canavanine" EXACT [PomBase:mah] synonym: "normal cell population growth on canavanine" BROAD [PomBase:mah] synonym: "normal cell population growth on L-canavanine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to L-canavanine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on L-canavanine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-14T14:23:13Z [Term] id: FYPO:0001546 name: decreased RNA level during cellular response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to zinc ion" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to zinc ion" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to zinc ion" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to zinc ion" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-09-14T14:26:22Z [Term] id: FYPO:0001547 name: increased RNA level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to zinc ion starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to zinc ion limitation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to zinc ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to zinc ion starvation" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-09-14T14:28:30Z [Term] id: FYPO:0001548 name: altered protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hydrogen peroxide. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "altered cellular protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:32:40Z [Term] id: FYPO:0001549 name: altered protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hypoxia. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein level during cellular response to hypoxia" EXACT [PomBase:mah] synonym: "altered cellular protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:34:37Z [Term] id: FYPO:0001550 name: altered protein level during cellular response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to zinc ions. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein level during cellular response to zinc ion" EXACT [PomBase:mah] synonym: "altered cellular protein level during cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to zinc" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:36:13Z [Term] id: FYPO:0001551 name: increased protein level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "increased protein level during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "increased protein level during cellular response to zinc ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to zinc starvation" EXACT [GO:0071453] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:37:37Z [Term] id: FYPO:0001552 name: increased cellular zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular zinc ion level" EXACT [PomBase:mah] synonym: "increased cellular zinc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular zinc level during vegetative growth" EXACT [PomBase:mah] synonym: "increased zinc accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T14:42:05Z [Term] id: FYPO:0001553 name: abnormal RNA processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is abnormal. RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." [GO:0006396, PomBase:mah] synonym: "abnormal RNA processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RNA processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2012-09-14T15:07:19Z [Term] id: FYPO:0001554 name: abnormal tRNA processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA processing is abnormal. tRNA processing is the conversion a primary tRNA transcript into a mature tRNA molecules." [GO:0008033, PomBase:mah] synonym: "abnormal tRNA processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tRNA processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2012-09-14T15:10:20Z [Term] id: FYPO:0001555 name: formation of abnormal tRNA processing intermediates def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the intermediate RNAs formed during tRNA processing differ from wild type in size." [PomBase:al, PomBase:mah] comment: Note that the mature tRNA may be of normal or abnormal size. synonym: "abnormal tRNA maturation intermediates" EXACT [PomBase:al] synonym: "formation of abnormal tRNA processing intermediates during mitotic cell cycle" RELATED [PomBase:mah] synonym: "formation of abnormal tRNA processing intermediates during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001554 ! abnormal tRNA processing created_by: midori creation_date: 2012-09-14T15:12:24Z [Term] id: FYPO:0001556 name: excess nuclear envelope present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more nuclear envelope than normal. Excess nuclear envelopes may take the form of intranuclear membrane stacks or invaginations, or small cytoplasmic spheres that are attached to the nucleus, have double lipid bilayer membranes, and may contain structures resembling nuclear pores." [PMID:22156749, PomBase:mah] synonym: "excess nuclear envelope present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "excess nuclear envelope present during vegetative growth" EXACT [PomBase:mah] synonym: "increased nuclear envelope proliferation" RELATED [PMID:22156749, PomBase:vw] synonym: "nuclear envelope present in greater amount" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2012-09-14T15:22:32Z [Term] id: FYPO:0001557 name: resistance to ethionine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethionine than normal." [PomBase:mah] comment: Note that a racemic mixture of D and L enantiomers of ethionine is usually used to test sensitivity or resistance. synonym: "resistance to DL-ethionine" RELATED [PomBase:mah] synonym: "resistance to ethionine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to ethionine during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to S-ethylhomocysteine" EXACT [CHEBI:68662, PomBase:mah] synonym: "resistant to ethionine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-09-14T16:15:57Z [Term] id: FYPO:0001558 name: decreased methionine import def: "A cellular process phenotype in which the import of methionine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-methionine import" EXACT [PomBase:mah] synonym: "decreased L-methionine import across plasma membrane" EXACT [GO:1905544] synonym: "decreased methionine import into cell" EXACT [PomBase:al] synonym: "decreased methionine transport into cell" EXACT [PomBase:al] synonym: "decreased methionine uptake" EXACT [PomBase:mah] synonym: "reduced methionine import" EXACT [PomBase:mah] synonym: "reduced methionine uptake" EXACT [PomBase:vw] is_a: FYPO:0001058 ! decreased amino acid import created_by: midori creation_date: 2012-09-14T16:32:14Z [Term] id: FYPO:0001559 name: normal methionine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methionine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal L-methionine import" EXACT [PomBase:mah] synonym: "normal L-methionine import across plasma membrane" EXACT [GO:1905544] synonym: "normal methionine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal methionine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal methionine import into cell" EXACT [PomBase:al] synonym: "normal methionine uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-09-14T16:34:42Z [Term] id: FYPO:0001560 name: decreased cellular threonine level alt_id: FYPO:0001614 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-threonine level" EXACT [PomBase:mah] synonym: "decreased cellular threonine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular threonine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of threonine in cell" EXACT [PomBase:mah] synonym: "decreased threonine accumulation" RELATED [PomBase:al] synonym: "reduced cellular threonine level" EXACT [PomBase:mah] synonym: "reduced level of threonine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:44:29Z [Term] id: FYPO:0001561 name: decreased cellular citrulline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-citrulline measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular citrulline level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular citrulline level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-citrulline level" EXACT [PomBase:mah] synonym: "decreased citrulline accumulation" RELATED [PomBase:al] synonym: "reduced cellular citrulline level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:45:19Z [Term] id: FYPO:0001562 name: decreased cellular histidine level alt_id: FYPO:0001620 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular histidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-histidine level" EXACT [PomBase:mah] synonym: "decreased histidine accumulation" RELATED [PomBase:al] synonym: "reduced cellular histidine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:46:05Z [Term] id: FYPO:0001563 name: decreased cellular glutamate level alt_id: FYPO:0001615 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glutamate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular glutamic acid level" RELATED [PomBase:mah] synonym: "decreased cellular L-glutamate level" EXACT [PomBase:mah] synonym: "decreased glutamate accumulation" RELATED [PomBase:al] synonym: "reduced cellular glutamate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:46:41Z [Term] id: FYPO:0001564 name: decreased cellular ornithine level alt_id: FYPO:0001618 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-ornithine level" EXACT [PomBase:mah] synonym: "decreased cellular ornithine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular ornithine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ornithine accumulation" RELATED [PomBase:al] synonym: "reduced cellular ornithine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:47:41Z [Term] id: FYPO:0001565 name: increased cellular threonine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-threonine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular threonine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular threonine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased threonine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:48:22Z [Term] id: FYPO:0001566 name: increased cellular citrulline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-citrulline measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular citrulline level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular citrulline level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-citrulline level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased citrulline accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:49:05Z [Term] id: FYPO:0001567 name: increased cellular histidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular histidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-histidine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased histidine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:49:35Z [Term] id: FYPO:0001568 name: increased cellular glutamate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutamate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-glutamate level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased glutamate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:50:25Z [Term] id: FYPO:0001569 name: increased cellular ornithine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-ornithine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular ornithine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular ornithine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased ornithine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:51:00Z [Term] id: FYPO:0001570 name: decreased cellular glutathione level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glutathione level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular GSH level during vegetative growth" EXACT [CHEBI:16856, PomBase:al] synonym: "decreased cellular L-gamma-glutamyl-L-cysteinylglycine level during vegetative growth" EXACT [CHEBI:16856] synonym: "decreased cellular reduced glutathione level during vegetative growth" EXACT [CHEBI:16856, PomBase:al] synonym: "decreased glutathione accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced cellular glutathione level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:51:27Z [Term] id: FYPO:0001571 name: increased protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "increased protein binding" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2012-09-20T13:22:04Z [Term] id: FYPO:0001572 name: abolished cell population growth on methionine nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-methionine as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with methionine as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on methionine nitrogen source" BROAD [PomBase:mah] synonym: "abolished methionine utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on methionine nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on methionine nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2012-09-20T13:55:30Z [Term] id: FYPO:0001573 name: increased RNA level during cellular response to rapamycin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to rapamycin is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to rapamycin" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to rapamycin" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to rapamycin" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-09-20T14:11:44Z [Term] id: FYPO:0001574 name: abnormal bipolar mitotic spindle def: "A physical cellular phenotype in which the mitotic spindle has two poles but is otherwise structurally abnormal." [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2012-09-20T14:36:56Z [Term] id: FYPO:0001575 name: abolished vegetative cell population growth def: "A cellular process phenotype in which vegetative cell population growth does not occur, although cells remain viable." [PomBase:mah] comment: This term's primary purpose is to organize terms beneath it in the ontology, and we recommend that it not be used for direct annotations. Please consider using one of the more specific terms, which mention carbon or nitrogen sources, to annotate each phenotype, as cells that do not grow on any media would be considered inviable. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abolished growth of population of viable vegetative cells" EXACT [PomBase:mah] synonym: "abolished vegetative cell population growth, viable cells" EXACT [PomBase:vw] synonym: "vegetative cell population growth abolished" EXACT [PomBase:mah] synonym: "vegetative population growth abolished" EXACT [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-09-20T14:52:12Z [Term] id: FYPO:0001576 name: abolished cell population growth on dipeptide nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a dipeptide such as Leu-Ala as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with a dipeptide as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished dipeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on dipeptide nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on dipeptide nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:01:27Z [Term] id: FYPO:0001577 name: abolished cell population growth on tetrapeptide nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with a tetrapeptide as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on tetrapeptide nitrogen source" BROAD [PomBase:mah] synonym: "abolished tetrapeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on tetrapeptide nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on tetrapeptide nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:03:18Z [Term] id: FYPO:0001578 name: normal growth on dipeptide nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing a dipeptide such as Leu-Ala as the nitrogen source." [PomBase:mah] synonym: "normal cell population growth on dipeptide nitrogen source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal dipeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on dipeptide nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:07:14Z [Term] id: FYPO:0001579 name: normal growth on tetrapeptide nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source." [PomBase:mah] synonym: "normal cell population growth on tetrapeptide nitrogen source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal tetrapeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on tetrapeptide nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:08:09Z [Term] id: FYPO:0001580 name: normal growth on leucine nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing leucine as the nitrogen source." [PomBase:mah] synonym: "normal cell population growth on leucine nitrogen source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on monomeric leucine nitrogen source" EXACT [PomBase:vw] synonym: "normal leucine utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "normal monomeric leucine utilization" RELATED [PomBase:vw] synonym: "normal vegetative cell population growth on leucine nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:08:58Z [Term] id: FYPO:0001581 name: vacuolated def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are more visible (usually by microscopy) than normal. A vacuolated phenotype may be due to the presence of more vacuoles in a cell than normal, or to vacuoles located nearer the cell surface (and hence more visible) than normal." [PomBase:mah] comment: Also see 'abnormal vacuole morphology (FYPO:0000368)' and 'vacuoles present in increased numbers' (FYPO:0000952). synonym: "vacuolated during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vacuolated during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2012-09-20T15:57:31Z [Term] id: FYPO:0001582 name: normal growth on glutathione def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing glutathione." [PomBase:mah] synonym: "normal cell population growth in presence of glutathione" EXACT [PomBase:mah] synonym: "normal cell population growth on glutathione" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on GSH" EXACT [CHEBI:16856] synonym: "normal cell population growth on L-gamma-glutamyl-L-cysteinylglycine" EXACT [CHEBI:16856] synonym: "normal cell population growth on reduced glutathione" EXACT [CHEBI:16856] synonym: "normal cellular response to glutathione" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on glutathione" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T16:02:56Z [Term] id: FYPO:0001583 name: resistance to lithium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lithium ions than normal." [PomBase:mah] synonym: "resistance to lithium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to lithium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to lithium ion" EXACT [PomBase:mah] synonym: "resistance to lithium ions" EXACT [PomBase:mah] synonym: "resistant to lithium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2012-09-21T15:24:01Z [Term] id: FYPO:0001584 name: abnormal protein localization to cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell tip and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell end during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0005987 ! abnormal protein localization to cell tip created_by: midori creation_date: 2012-09-21T15:26:12Z [Term] id: FYPO:0001585 name: abolished protein localization to cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell end during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to cell tip abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2012-09-21T15:26:25Z [Term] id: FYPO:0001586 name: decreased protein localization to cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell end during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2012-09-21T15:26:32Z [Term] id: FYPO:0001587 name: normal protein localization to cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cell end during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2012-09-21T15:26:58Z [Term] id: FYPO:0001588 name: decreased lysine import during nitrogen starvation def: "A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "decreased L-lysine import across plasma membrane during nitrogen starvation" EXACT [GO:0097639] synonym: "decreased L-lysine import during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased lysine import during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased lysine import during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased lysine import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased lysine transport into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased lysine uptake during nitrogen starvation" EXACT [PomBase:mah] synonym: "reduced lysine import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001650 ! decreased lysine import is_a: FYPO:0001652 ! abnormal lysine import during nitrogen starvation created_by: midori creation_date: 2012-09-27T11:07:56Z [Term] id: FYPO:0001589 name: decreased glutamate import during nitrogen starvation def: "A cellular process phenotype in which the import of glutamate into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "decreased glutamate import during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased glutamate import during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased glutamate import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased glutamate transport into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased glutamate uptake during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased L-glutamate import across plasma membrane during nitrogen starvation" EXACT [GO:0098712] synonym: "decreased L-glutamate import during nitrogen starvation" EXACT [PomBase:mah] synonym: "reduced glutamate import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001647 ! abnormal glutamate import during nitrogen starvation is_a: FYPO:0001649 ! decreased glutamate import created_by: midori creation_date: 2012-09-27T11:08:38Z [Term] id: FYPO:0001590 name: decreased lysine import during vegetative growth def: "A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased L-lysine import across plasma membrane during vegetative growth" EXACT [GO:0097639] synonym: "decreased L-lysine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lysine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased lysine import into cell during vegetative growth" EXACT [PomBase:al] synonym: "decreased lysine uptake during vegetative growth" EXACT [PomBase:mah] synonym: "reduced lysine import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001650 ! decreased lysine import is_a: FYPO:0001653 ! abnormal lysine import during vegetative growth created_by: midori creation_date: 2012-09-27T11:36:23Z [Term] id: FYPO:0001591 name: decreased histidine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of histidine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histidine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histidine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histidine import into cell" EXACT [PomBase:al] synonym: "decreased histidine uptake" EXACT [PomBase:mah] synonym: "decreased L-histidine import" EXACT [PomBase:mah] synonym: "decreased L-histidine import across plasma membrane" EXACT [GO:1903810] synonym: "reduced histidine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001655 ! abnormal histidine import created_by: midori creation_date: 2012-09-27T11:37:19Z [Term] id: FYPO:0001592 name: decreased arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased arginine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased arginine import into cell" EXACT [PomBase:al] synonym: "decreased arginine uptake" EXACT [PomBase:mah] synonym: "decreased L-arginine import" EXACT [PomBase:mah] synonym: "decreased L-arginine import across plasma membrane" EXACT [GO:0097638] synonym: "reduced arginine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001654 ! abnormal arginine import created_by: midori creation_date: 2012-09-27T11:59:09Z [Term] id: FYPO:0001593 name: decreased valine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of valine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-valine import" EXACT [PomBase:mah] synonym: "decreased L-valine import across plasma membrane" EXACT [GO:1903805] synonym: "decreased valine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased valine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased valine import into cell" EXACT [PomBase:al] synonym: "decreased valine uptake" EXACT [PomBase:mah] synonym: "reduced valine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001658 ! abnormal valine import created_by: midori creation_date: 2012-09-27T11:59:59Z [Term] id: FYPO:0001594 name: decreased asparagine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of asparagine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased asparagine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased asparagine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased asparagine import into cell" EXACT [PomBase:al] synonym: "decreased asparagine uptake" EXACT [PomBase:mah] synonym: "decreased L-asparagine import" EXACT [PomBase:mah] synonym: "decreased L-asparagine import across plasma membrane" EXACT [GO:1903811] synonym: "reduced asparagine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001656 ! abnormal asparagine import created_by: midori creation_date: 2012-09-27T12:00:40Z [Term] id: FYPO:0001595 name: decreased serine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of serine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-serine import" EXACT [PomBase:mah] synonym: "decreased L-serine import across plasma membrane" EXACT [GO:1903812] synonym: "decreased serine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased serine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased serine import into cell" EXACT [PomBase:al] synonym: "decreased serine uptake" EXACT [PomBase:mah] synonym: "reduced serine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001657 ! abnormal serine import created_by: midori creation_date: 2012-09-27T12:01:24Z [Term] id: FYPO:0001596 name: normal amino acid import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which amino acid import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal amino acid import across plasma membrane" EXACT [GO:0089718] synonym: "normal amino acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal amino acid import during vegetative growth" EXACT [PomBase:mah] synonym: "normal amino acid import into cell" EXACT [PomBase:al] synonym: "normal amino acid uptake" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-09-27T12:17:29Z [Term] id: FYPO:0001597 name: normal valine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which valine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal L-valine import" EXACT [PomBase:mah] synonym: "normal L-valine import across plasma membrane" EXACT [GO:1903805] synonym: "normal valine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal valine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal valine import into cell" EXACT [PomBase:al] synonym: "normal valine uptake" EXACT [PomBase:mah] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:22:29Z [Term] id: FYPO:0001598 name: normal glutamine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which glutamine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glutamine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal glutamine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal glutamine import into cell" EXACT [PomBase:al] synonym: "normal glutamine uptake" EXACT [PomBase:mah] synonym: "normal L-glutamine import" EXACT [PomBase:mah] synonym: "normal L-glutamine import across plasma membrane" EXACT [GO:1903803] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:23:11Z [Term] id: FYPO:0001599 name: normal asparagine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which asparagine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal asparagine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal asparagine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal asparagine import into cell" EXACT [PomBase:al] synonym: "normal asparagine uptake" EXACT [PomBase:mah] synonym: "normal L-asparagine import" EXACT [PomBase:mah] synonym: "normal L-asparagine import across plasma membrane" EXACT [GO:1903811] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:23:36Z [Term] id: FYPO:0001600 name: normal isoleucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which isoleucine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal isoleucine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal isoleucine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal isoleucine import into cell" EXACT [PomBase:al] synonym: "normal isoleucine uptake" EXACT [PomBase:mah] synonym: "normal L-isoleucine import" EXACT [PomBase:mah] synonym: "normal L-isoleucine import across plasma membrane" EXACT [GO:1903806] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:24:12Z [Term] id: FYPO:0001601 name: altered level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole differs from normal." [PomBase:mah] synonym: "abnormal level of substance in vacuole" EXACT [PomBase:mah] synonym: "abnormal level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vacuolar level of substance" EXACT [PomBase:mah] synonym: "altered level of substance in vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered vacuolar level of substance" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:06:05Z [Term] id: FYPO:0001602 name: decreased level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of substance in vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar level of substance" EXACT [PomBase:mah] synonym: "reduced level of substance in vacuole" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001601 ! altered level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:07:26Z [Term] id: FYPO:0001603 name: normal level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of substance in vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar level of substance" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:07:41Z [Term] id: FYPO:0001604 name: altered level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol differs from normal." [PomBase:mah] synonym: "abnormal cytosolic level of substance" EXACT [PomBase:mah] synonym: "abnormal level of substance in cytosol" EXACT [PomBase:mah] synonym: "abnormal level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] synonym: "altered cytosolic level of substance" EXACT [PomBase:mah] synonym: "altered level of substance in cytosol during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:17:34Z [Term] id: FYPO:0001605 name: decreased level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is lower than normal." [PomBase:mah] synonym: "decreased cytosolic level of substance" EXACT [PomBase:mah] synonym: "decreased level of substance in cytosol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of substance in cytosol" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001604 ! altered level of substance in cytosol created_by: midori creation_date: 2012-09-27T13:18:39Z [Term] id: FYPO:0001606 name: normal level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cytosolic level of substance" EXACT [PomBase:mah] synonym: "normal level of substance in cytosol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:19:00Z [Term] id: FYPO:0001607 name: decreased vacuolar aspartate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of aspartate in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar aspartate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar aspartate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar aspartic acid level" RELATED [PomBase:mah] synonym: "decreased vacuolar L-aspartate level" EXACT [PomBase:mah] synonym: "reduced level of aspartate in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar aspartate level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001613 ! decreased cellular aspartate level created_by: midori creation_date: 2012-09-27T13:35:58Z [Term] id: FYPO:0001608 name: decreased vacuolar glutamate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of glutamate in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar glutamate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar glutamic acid level" RELATED [PomBase:mah] synonym: "decreased vacuolar L-glutamate level" EXACT [PomBase:mah] synonym: "reduced level of glutamate in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar glutamate level" EXACT [PomBase:mah] is_a: FYPO:0001563 ! decreased cellular glutamate level is_a: FYPO:0001602 ! decreased level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:37:52Z [Term] id: FYPO:0001609 name: decreased vacuolar ornithine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of ornithine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar L-ornithine level" EXACT [PomBase:mah] synonym: "decreased vacuolar ornithine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar ornithine level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of ornithine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar ornithine level" EXACT [PomBase:mah] is_a: FYPO:0001564 ! decreased cellular ornithine level is_a: FYPO:0001602 ! decreased level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:38:40Z [Term] id: FYPO:0001610 name: decreased vacuolar lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of lysine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar L-lysine level" EXACT [PomBase:mah] synonym: "decreased vacuolar lysine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar lysine level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of lysine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar lysine level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001619 ! decreased cellular lysine level created_by: midori creation_date: 2012-09-27T13:40:52Z [Term] id: FYPO:0001611 name: decreased vacuolar histidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of histidine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar histidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar L-histidine level" EXACT [PomBase:mah] synonym: "reduced level of histidine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar histidine level" EXACT [PomBase:mah] is_a: FYPO:0001562 ! decreased cellular histidine level is_a: FYPO:0001602 ! decreased level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:41:34Z [Term] id: FYPO:0001612 name: decreased vacuolar arginine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of arginine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar arginine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar arginine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar L-arginine level" EXACT [PomBase:mah] synonym: "reduced level of arginine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar arginine level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001621 ! decreased cellular arginine level created_by: midori creation_date: 2012-09-27T13:42:12Z [Term] id: FYPO:0001613 name: decreased cellular aspartate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular aspartate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular aspartate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular aspartic acid level" RELATED [PomBase:mah] synonym: "decreased cellular L-aspartate level" EXACT [PomBase:mah] synonym: "decreased cellular level aspartate level" EXACT [PomBase:mah] synonym: "decreased level of aspartate in cell" EXACT [PomBase:mah] synonym: "reduced cellular aspartate level" EXACT [PomBase:mah] synonym: "reduced level of aspartate in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:57:23Z [Term] id: FYPO:0001616 name: decreased cellular valine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-valine level" EXACT [PomBase:mah] synonym: "decreased cellular valine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular valine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of valine in cell" EXACT [PomBase:mah] synonym: "reduced cellular valine level" EXACT [PomBase:mah] synonym: "reduced level of valine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:00:08Z [Term] id: FYPO:0001617 name: decreased cellular isoleucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular isoleucine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular isoleucine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-isoleucine level" EXACT [PomBase:mah] synonym: "decreased level of isoleucine in cell" EXACT [PomBase:mah] synonym: "reduced cellular isoleucine level" EXACT [PomBase:mah] synonym: "reduced level of isoleucine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:02:19Z [Term] id: FYPO:0001619 name: decreased cellular lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-lysine level" EXACT [PomBase:mah] synonym: "decreased cellular lysine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular lysine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of lysine in cell" EXACT [PomBase:mah] synonym: "reduced cellular lysine level" EXACT [PomBase:mah] synonym: "reduced level of lysine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:03:22Z [Term] id: FYPO:0001621 name: decreased cellular arginine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular arginine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular arginine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-arginine level" EXACT [PomBase:mah] synonym: "decreased level of arginine in cell" EXACT [PomBase:mah] synonym: "reduced cellular arginine level" EXACT [PomBase:mah] synonym: "reduced level of arginine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:04:37Z [Term] id: FYPO:0001622 name: normal vacuolar threonine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of threonine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-threonine level" EXACT [PomBase:mah] synonym: "normal vacuolar threonine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar threonine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:07:43Z [Term] id: FYPO:0001623 name: normal vacuolar serine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of serine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-serine level" EXACT [PomBase:mah] synonym: "normal vacuolar serine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar serine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001635 ! normal cellular serine level created_by: midori creation_date: 2012-09-27T14:15:13Z [Term] id: FYPO:0001624 name: normal vacuolar asparagine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of asparagine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar asparagine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar asparagine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-asparagine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:15:39Z [Term] id: FYPO:0001625 name: normal vacuolar glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of glutamine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar glutamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-glutamine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001636 ! normal cellular glutamine level created_by: midori creation_date: 2012-09-27T14:16:08Z [Term] id: FYPO:0001626 name: normal vacuolar glycine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of glycine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar glycine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar glycine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001637 ! normal cellular glycine level created_by: midori creation_date: 2012-09-27T14:16:32Z [Term] id: FYPO:0001627 name: normal vacuolar alanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of alanine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar alanine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar alanine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-alanine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001638 ! normal cellular alanine level created_by: midori creation_date: 2012-09-27T14:17:07Z [Term] id: FYPO:0001628 name: normal vacuolar valine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of valine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-valine level" EXACT [PomBase:mah] synonym: "normal vacuolar valine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar valine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0002746 ! normal cellular valine level created_by: midori creation_date: 2012-09-27T14:18:04Z [Term] id: FYPO:0001629 name: normal vacuolar methionine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of methionine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-methionine level" EXACT [PomBase:mah] synonym: "normal vacuolar methionine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar methionine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001639 ! normal cellular methionine level created_by: midori creation_date: 2012-09-27T14:18:27Z [Term] id: FYPO:0001630 name: normal vacuolar isoleucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of isoleucine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar isoleucine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar isoleucine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-isoleucine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:18:49Z [Term] id: FYPO:0001631 name: normal vacuolar leucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-leucine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of leucine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-leucine level" EXACT [PomBase:mah] synonym: "normal vacuolar leucine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar leucine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001640 ! normal cellular leucine level created_by: midori creation_date: 2012-09-27T14:19:17Z [Term] id: FYPO:0001632 name: normal vacuolar tyrosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of tyrosine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-tyrosine level" EXACT [PomBase:mah] synonym: "normal vacuolar tyrosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar tyrosine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001641 ! normal cellular tyrosine level created_by: midori creation_date: 2012-09-27T14:20:13Z [Term] id: FYPO:0001633 name: normal vacuolar phenylalanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-phenylalanine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of phenylalanine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-phenylalanine level" EXACT [PomBase:mah] synonym: "normal vacuolar phenylalanine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar phenylalanine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001642 ! normal cellular phenylalanine level created_by: midori creation_date: 2012-09-27T14:20:37Z [Term] id: FYPO:0001634 name: normal vacuolar tryptophan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of tryptophan measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of tryptophan in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar tryptophan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar tryptophan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001643 ! normal cellular tryptophan level created_by: midori creation_date: 2012-09-27T14:21:05Z [Term] id: FYPO:0001635 name: normal cellular serine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-serine level" EXACT [PomBase:mah] synonym: "normal cellular serine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular serine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of serine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:42:14Z [Term] id: FYPO:0001636 name: normal cellular glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular glutamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-glutamine level" EXACT [PomBase:mah] synonym: "normal level of glutamine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:43:22Z [Term] id: FYPO:0001637 name: normal cellular glycine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glycine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular glycine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular glycine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-glycine level" EXACT [PomBase:mah] synonym: "normal level of glycine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:43:46Z [Term] id: FYPO:0001638 name: normal cellular alanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular alanine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular alanine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-alanine level" EXACT [PomBase:mah] synonym: "normal level of alanine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:44:07Z [Term] id: FYPO:0001639 name: normal cellular methionine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-methionine level" EXACT [PomBase:mah] synonym: "normal cellular methionine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular methionine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of methionine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:44:34Z [Term] id: FYPO:0001640 name: normal cellular leucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-leucine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-leucine level" EXACT [PomBase:mah] synonym: "normal cellular leucine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular leucine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of leucine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:44:59Z [Term] id: FYPO:0001641 name: normal cellular tyrosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-tyrosine level" EXACT [PomBase:mah] synonym: "normal cellular tyrosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular tyrosine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of tyrosine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:45:39Z [Term] id: FYPO:0001642 name: normal cellular phenylalanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-phenylalanine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-phenylalanine level" EXACT [PomBase:mah] synonym: "normal cellular phenylalanine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phenylalanine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of phenylalanine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:46:14Z [Term] id: FYPO:0001643 name: normal cellular tryptophan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of tryptophan measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular tryptophan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular tryptophan level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of tryptophan in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:46:41Z [Term] id: FYPO:0001644 name: decreased cellular lithium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lithium ions measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular lithium ion level" EXACT [PomBase:mah] synonym: "decreased cellular lithium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular lithium level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lithium accumulation" RELATED [PomBase:al] synonym: "reduced cellular lithium level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:48:30Z [Term] id: FYPO:0001645 name: decreased protein-protein interaction alt_id: FYPO:0004636 def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding" EXACT [PomBase:mah] synonym: "reduced protein-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2012-09-27T14:50:07Z [Term] id: FYPO:0001646 name: abnormal glutamate import def: "A cellular process phenotype in which the import of glutamate into the cell is abnormal." [PomBase:mah] synonym: "abnormal glutamate import into cell" EXACT [PomBase:al] synonym: "abnormal glutamate uptake" EXACT [PomBase:mah] synonym: "abnormal L-glutamate import" EXACT [PomBase:mah] synonym: "abnormal L-glutamate import across plasma membrane" EXACT [GO:0098712] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0001057 ! abnormal amino acid import created_by: midori creation_date: 2012-09-27T15:50:49Z [Term] id: FYPO:0001647 name: abnormal glutamate import during nitrogen starvation def: "A cellular process phenotype in which the import of L-glutamate into the cell is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal glutamate import during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal glutamate import during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal glutamate import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "abnormal glutamate uptake during nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal L-glutamate import across plasma membrane during nitrogen starvation" EXACT [GO:0098712] synonym: "abnormal L-glutamate import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001646 ! abnormal glutamate import created_by: midori creation_date: 2012-09-27T15:51:52Z [Term] id: FYPO:0001648 name: abnormal amino acid import during nitrogen starvation def: "A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal amino acid import across plasma membrane during nitrogen starvation" EXACT [GO:0089718] synonym: "abnormal amino acid import during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal amino acid import during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal amino acid import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "abnormal amino acid uptake during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001057 ! abnormal amino acid import created_by: midori creation_date: 2012-09-27T15:54:34Z [Term] id: FYPO:0001649 name: decreased glutamate import def: "A cellular process phenotype in which the import of glutamate into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased glutamate import across plasma membrane" EXACT [GO:0098712] synonym: "decreased glutamate import into cell" EXACT [PomBase:al] synonym: "decreased glutamate uptake" EXACT [PomBase:mah] synonym: "decreased L-glutamate import" EXACT [PomBase:mah] synonym: "reduced glutamate import" EXACT [PomBase:mah] is_a: FYPO:0001058 ! decreased amino acid import is_a: FYPO:0001646 ! abnormal glutamate import created_by: midori creation_date: 2012-09-27T15:56:47Z [Term] id: FYPO:0001650 name: decreased lysine import def: "A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-lysine import" EXACT [PomBase:mah] synonym: "decreased L-lysine import across plasma membrane" EXACT [GO:0097639] synonym: "decreased lysine import into cell" EXACT [PomBase:al] synonym: "decreased lysine uptake" EXACT [PomBase:mah] synonym: "reduced lysine import" EXACT [PomBase:mah] is_a: FYPO:0001058 ! decreased amino acid import is_a: FYPO:0001651 ! abnormal lysine import created_by: midori creation_date: 2012-09-27T15:59:41Z [Term] id: FYPO:0001651 name: abnormal lysine import def: "A cellular process phenotype in which the import of lysine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-lysine import" EXACT [PomBase:mah] synonym: "abnormal L-lysine import across plasma membrane" EXACT [GO:0097639] synonym: "abnormal lysine import into cell" EXACT [PomBase:al] synonym: "abnormal lysine uptake" EXACT [PomBase:mah] is_a: FYPO:0001057 ! abnormal amino acid import created_by: midori creation_date: 2012-09-27T16:06:07Z [Term] id: FYPO:0001652 name: abnormal lysine import during nitrogen starvation def: "A cellular process phenotype in which the import of lysine into the cell is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal L-lysine import across plasma membrane during nitrogen starvation" EXACT [GO:0097639] synonym: "abnormal L-lysine import during nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal lysine import during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal lysine import during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal lysine import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "abnormal lysine uptake during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001651 ! abnormal lysine import created_by: midori creation_date: 2012-09-27T16:07:08Z [Term] id: FYPO:0001653 name: abnormal lysine import during vegetative growth def: "A cellular process phenotype in which the import of lysine into the cell is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal L-lysine import across plasma membrane during vegetative growth" EXACT [GO:0097639] synonym: "abnormal L-lysine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal lysine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal lysine import into cell during vegetative growth" EXACT [PomBase:al] synonym: "abnormal lysine uptake during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001651 ! abnormal lysine import created_by: midori creation_date: 2012-09-27T16:07:33Z [Term] id: FYPO:0001654 name: abnormal arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell is abnormal." [PomBase:mah] synonym: "abnormal arginine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal arginine import into cell" EXACT [PomBase:al] synonym: "abnormal arginine uptake" EXACT [PomBase:mah] synonym: "abnormal L-arginine import" EXACT [PomBase:mah] synonym: "abnormal L-arginine import across plasma membrane" EXACT [GO:0097638] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-09-27T16:12:15Z [Term] id: FYPO:0001655 name: abnormal histidine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of histidine into the cell is abnormal." [PomBase:mah] synonym: "abnormal histidine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histidine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histidine import into cell" EXACT [PomBase:al] synonym: "abnormal histidine uptake" EXACT [PomBase:mah] synonym: "abnormal L-histidine import" EXACT [PomBase:mah] synonym: "abnormal L-histidine import across plasma membrane" EXACT [GO:1903810] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-09-27T16:13:44Z [Term] id: FYPO:0001656 name: abnormal asparagine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of asparagine into the cell is abnormal." [PomBase:mah] synonym: "abnormal asparagine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal asparagine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal asparagine import into cell" EXACT [PomBase:al] synonym: "abnormal asparagine uptake" EXACT [PomBase:mah] synonym: "abnormal L-asparagine import" EXACT [PomBase:mah] synonym: "abnormal L-asparagine import across plasma membrane" EXACT [GO:1903811] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-09-27T16:15:26Z [Term] id: FYPO:0001657 name: abnormal serine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of serine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-serine import" EXACT [PomBase:mah] synonym: "abnormal L-serine import across plasma membrane" EXACT [GO:1903812] synonym: "abnormal serine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal serine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal serine import into cell" EXACT [PomBase:al] synonym: "abnormal serine uptake" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-09-27T16:16:18Z [Term] id: FYPO:0001658 name: abnormal valine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of valine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-valine import" EXACT [PomBase:mah] synonym: "abnormal L-valine import across plasma membrane" EXACT [GO:1903805] synonym: "abnormal valine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal valine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal valine import into cell" EXACT [PomBase:al] synonym: "abnormal valine uptake" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-09-27T16:17:09Z [Term] id: FYPO:0001659 name: altered cellular cAMP level def: "A cell phenotype in which the amount of cyclic AMP measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular cAMP accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular cAMP level" EXACT [PomBase:mah] synonym: "altered cellular cyclic AMP level" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-10-03T15:56:44Z [Term] id: FYPO:0001660 name: decreased cellular cAMP level def: "A cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular cAMP accumulation" RELATED [PomBase:mah] synonym: "decreased cellular cyclic AMP level" EXACT [PomBase:mah] synonym: "reduced cellular cAMP level" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0001659 ! altered cellular cAMP level created_by: midori creation_date: 2012-10-03T15:56:53Z [Term] id: FYPO:0001661 name: increased cellular cAMP level def: "A cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cAMP accumulation" RELATED [PomBase:mah] synonym: "increased cellular cAMP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular cAMP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular cyclic AMP level" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001659 ! altered cellular cAMP level created_by: midori creation_date: 2012-10-03T15:57:15Z [Term] id: FYPO:0001662 name: decreased cellular cAMP level during glucose starvation def: "A cell phenotype in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased cellular cAMP accumulation during glucose starvation" RELATED [PomBase:mah] synonym: "decreased cellular cAMP level during glucose depletion" EXACT [PomBase:vw] synonym: "decreased cellular cAMP level during glucose deprivation" EXACT [PomBase:vw] synonym: "decreased cellular cAMP level during glucose limitation" RELATED [PomBase:mah] synonym: "decreased cellular cyclic AMP level during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "reduced cellular cAMP level during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001660 ! decreased cellular cAMP level created_by: midori creation_date: 2012-10-03T15:57:38Z [Term] id: FYPO:0001663 name: increased cellular cAMP level during glucose starvation def: "A cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "increased cAMP accumulation during cellular response to glucose starvation" RELATED [PomBase:mah] synonym: "increased cellular cAMP level during glucose depletion" EXACT [PomBase:vw] synonym: "increased cellular cAMP level during glucose deprivation" EXACT [PomBase:vw] synonym: "increased cellular cAMP level during glucose limitation" RELATED [PomBase:mah] synonym: "increased cellular cAMP level in response to glucose starvation" EXACT [PomBase:al] synonym: "increased cellular cyclic AMP level and during cellular response to glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001661 ! increased cellular cAMP level created_by: midori creation_date: 2012-10-03T15:58:30Z [Term] id: FYPO:0001664 name: increased cellular cAMP level during cellular response to glucose stimulus def: "A cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal during a cellular response to glucose stimulus." [PomBase:mah] synonym: "increased cAMP accumulation during cellular response to glucose stimulus" RELATED [PomBase:mah] synonym: "increased cellular cAMP level in response to glucose stimulus" EXACT [PomBase:al] synonym: "increased cellular cyclic AMP level during cellular response to glucose stimulus" EXACT [PomBase:mah] is_a: FYPO:0001661 ! increased cellular cAMP level created_by: midori creation_date: 2012-10-03T16:03:24Z [Term] id: FYPO:0001665 name: decreased cellular cAMP level during cellular response to glucose stimulus def: "A cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal during a cellular response to glucose stimulus." [PomBase:mah] synonym: "decreased cAMP accumulation during cellular response to glucose stimulus" RELATED [PomBase:mah] synonym: "decreased cellular cAMP level in response to glucose stimulus" EXACT [PomBase:al] synonym: "decreased cellular cyclic AMP level during cellular response to glucose stimulus" EXACT [PomBase:mah] synonym: "reduced cellular cAMP level during cellular response to glucose stimulus" EXACT [PomBase:mah] is_a: FYPO:0001660 ! decreased cellular cAMP level created_by: midori creation_date: 2012-10-03T16:07:39Z [Term] id: FYPO:0001666 name: normal cAMP level def: "A cell phenotype in which the amount of cyclic AMP measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular cAMP level" EXACT [PomBase:mah] synonym: "normal cyclic AMY level" EXACT [PomBase:mah] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2012-10-03T16:09:21Z [Term] id: FYPO:0001667 name: normal cAMP level during glucose starvation def: "A cell phenotype in which the amount of cyclic AMP measured in a cell during glucose starvation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal cAMP accumulation during glucose starvation" RELATED [PomBase:mah] synonym: "normal cAMP level during glucose depletion" EXACT [PomBase:vw] synonym: "normal cAMP level during glucose deprivation" EXACT [PomBase:vw] synonym: "normal cAMP level during glucose limitation" RELATED [PomBase:mah] synonym: "normal cellular cAMP level during glucose starvation" EXACT [PomBase:mah] synonym: "normal cyclic AMP level during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001666 ! normal cAMP level created_by: midori creation_date: 2012-10-03T16:09:33Z [Term] id: FYPO:0001668 name: normal protein processing during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein processing is normal (i.e. indistinguishable from wild type). Protein processing is any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein." [GO:0016485, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein processing during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002800 ! normal protein degradation during vegetative growth created_by: midori creation_date: 2012-10-03T16:16:56Z [Term] id: FYPO:0001669 name: abolished protein processing during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the protein processing does not occur. Processing of all proteins or of one or more specific proteins may be affected. Protein processing is any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein." [GO:0016485, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein processing abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001421 ! abnormal protein processing during vegetative growth created_by: midori creation_date: 2012-10-03T16:25:27Z [Term] id: FYPO:0001670 name: abnormal GDP binding def: "A molecular function phenotype in which occurrence of GDP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GDP differently from wild type, or that a mutation in one gene affects GDP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-10-03T16:29:51Z [Term] id: FYPO:0001671 name: decreased GDP binding def: "A molecular function phenotype in which occurrence of GDP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced GDP binding" EXACT [PomBase:mah] is_a: FYPO:0001670 ! abnormal GDP binding created_by: midori creation_date: 2012-10-03T16:29:57Z [Term] id: FYPO:0001672 name: normal GTPase activity def: "A molecular function phenotype in which the observed rate of a GTPase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-10-03T16:35:01Z [Term] id: FYPO:0001673 name: normal nuclear morphology def: "A physical cellular phenotype in which the size, shape, or structure of the nucleus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2012-10-09T10:53:23Z [Term] id: FYPO:0001674 name: abnormal L-aminoadipate-semialdehyde dehydrogenase activity def: "A molecular function phenotype in which the observed rate of L-aminoadipate-semialdehyde dehydrogenase activity is abnormal." [PomBase:mah] synonym: "abnormal alpha-aminoadipate reductase activity" EXACT [GO:0004043] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-10-11T14:46:46Z [Term] id: FYPO:0001675 name: increased L-aminoadipate-semialdehyde dehydrogenase activity def: "A molecular function phenotype in which the observed rate of L-aminoadipate-semialdehyde dehydrogenase activity is increased." [PomBase:mah] synonym: "increased alpha-aminoadipate reductase activity" EXACT [GO:0004043] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001674 ! abnormal L-aminoadipate-semialdehyde dehydrogenase activity created_by: midori creation_date: 2012-10-11T14:46:54Z [Term] id: FYPO:0001676 name: protein mislocalized to nucleus during mitotic S phase def: "A cell phenotype in which a protein that is not normally found in the nucleus is observed there during S phase of a mitotic cell cycle." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleus during mitotic S phase" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleus during mitotic S phase" EXACT [PomBase:mah] synonym: "protein mislocalised to nucleus during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during S phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2012-10-11T16:20:13Z [Term] id: FYPO:0001677 name: increased protein localization to medial cortex during vegetative growth def: "A cell phenotype in which the localization of a protein to the medial cortex is increased in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to medial cortex during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "increased protein localization to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0000731 ! abnormal protein localization to medial cortex during vegetative growth created_by: midori creation_date: 2012-10-29T11:40:14Z [Term] id: FYPO:0001678 name: abolished protein localization to chromatin def: "A cell phenotype in which the localization of a protein to chromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin" EXACT [PomBase:mah] synonym: "protein localization to chromatin abolished" EXACT [PomBase:mah] is_a: FYPO:0001679 ! abnormal protein localization to chromatin created_by: midori creation_date: 2012-10-30T15:29:03Z [Term] id: FYPO:0001679 name: abnormal protein localization to chromatin def: "A cell phenotype in which the localization of a protein to chromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term or its descendants. synonym: "abnormal protein localisation to chromatin" EXACT [GO:0071168, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-10-30T15:39:19Z [Term] id: FYPO:0001680 name: abolished protein localization to chromatin during premeiotic DNA replication def: "A cell phenotype in which the localization of a protein to chromatin is abolished during the round of DNA replication that precedes meiosis I." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin during premeiotic DNA replication" EXACT [PomBase:mah] synonym: "protein localization to chromatin during premeiotic DNA replication abolished" EXACT [PomBase:mah] is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2012-10-30T15:42:30Z [Term] id: FYPO:0001681 name: abolished protein localization to chromatin during S phase of meiotic cell cycle def: "A cell phenotype in which the localization of a protein to chromatin is abolished during S phase of a meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin during S phase of meiotic cell cycle" EXACT [PomBase:mah] synonym: "protein localization to chromatin during S phase of meiotic cell cycle abolished" EXACT [PomBase:mah] is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2012-10-30T15:50:10Z [Term] id: FYPO:0001682 name: normal alpha,alpha-trehalase activity increase during cellular response to salt stress def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of a salt stress." [PomBase:mah] synonym: "normal increase in trehalase activity in response to salt stress" EXACT [PomBase:al] synonym: "normal neutral trehalase activity increase during cellular response to salt stress" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity increase during cellular response to salt stress" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001480 ! normal alpha,alpha-trehalase activity created_by: midori creation_date: 2012-11-02T14:52:25Z [Term] id: FYPO:0001683 name: abolished mitotic spindle assembly def: "A cell phenotype in which mitotic spindle assembly does not occur." [PomBase:mah] synonym: "abolished mitotic spindle assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished spindle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle assembly involved in mitosis abolished" EXACT [PomBase:mah] is_a: FYPO:0000177 ! abnormal mitotic spindle assembly relationship: has_output FYPO:0002018 ! mitotic spindle absent from cell created_by: midori creation_date: 2012-11-02T15:04:44Z [Term] id: FYPO:0001684 name: decreased RNA level during cellular response to purvalanol A def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to purvalanol A" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to purvalanol A" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to purvalanol A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to purvalanol A during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to purvalanol A" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to purvalanol A" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-11-02T15:37:15Z [Term] id: FYPO:0001685 name: increased RNA level during cellular response to purvalanol A def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to purvalanol A" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to purvalanol A" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to purvalanol A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to purvalanol A during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to purvalanol A" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-11-02T15:39:06Z [Term] id: FYPO:0001686 name: normal growth on carbendazim def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the tubulin poison carbendazim (mecarzole; MBC)." [PomBase:mah] synonym: "normal cell population growth in presence of carbendazim" EXACT [PomBase:mah] synonym: "normal cell population growth on carbendazim" EXACT [CHEBI:3392, PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on mecarzole" EXACT [CHEBI:3392, PomBase:al] synonym: "normal cellular response to carbendazim" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on MBC" EXACT [CHEBI:3392] synonym: "normal growth on methyl benzimidazole-2-yl-carbamate" EXACT [CHEBI:3392] synonym: "normal growth on methylbenzylcarbamylate" EXACT [PMID:\:8247131] synonym: "normal vegetative cell population growth on carbendazim" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-02T15:43:07Z [Term] id: FYPO:0001687 name: normal growth on benomyl def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing benomyl." [PomBase:mah] synonym: "normal cell population growth in presence of benomyl" EXACT [PomBase:mah] synonym: "normal cell population growth on benomyl" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on methyl benzimidazole-2-yl-carbamate" EXACT [PMID:6887244] synonym: "normal cellular response to benomyl" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate" EXACT [CHEBI:3015] synonym: "normal vegetative cell population growth on benomyl" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-02T15:45:13Z [Term] id: FYPO:0001688 name: normal growth on brefeldin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing brefeldin A." [PomBase:mah] synonym: "normal cell population growth in presence of brefeldin A" EXACT [PomBase:mah] synonym: "normal cell population growth on BFA" EXACT [PomBase:mah] synonym: "normal cell population growth on brefeldin A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to brefeldin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on brefeldin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-02T15:47:41Z [Term] id: FYPO:0001689 name: normal growth on 4-nitroquinoline N-oxide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 4-nitroquinoline N-oxide." [PomBase:mah] synonym: "normal cell population growth in presence of 4-nitroquinoline N-oxide" EXACT [PomBase:mah] synonym: "normal cell population growth on 4-nitroquinoline N-oxide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on 4-NQO" EXACT [PomBase:mah] synonym: "normal cell population growth on 4NQO" EXACT [PomBase:al] synonym: "normal cellular response to 4-nitroquinoline N-oxide" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on 4-nitroquinoline N-oxide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-02T15:50:35Z [Term] id: FYPO:0001690 name: normal growth on camptothecin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing camptothecin." [PomBase:mah] synonym: "normal cell population growth in presence of camptothecin" EXACT [PomBase:mah] synonym: "normal cell population growth on camptothecin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on CPT" EXACT [PomBase:al] synonym: "normal cellular response to camptothecin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on camptothecin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-02T15:52:52Z [Term] id: FYPO:0001691 name: normal growth on paraquat def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing paraquat." [PomBase:mah] synonym: "normal cell population growth in presence of paraquat" EXACT [PomBase:mah] synonym: "normal cell population growth on paraquat" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to paraquat" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on paraquat" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-02T15:54:56Z [Term] id: FYPO:0001692 name: sensitive to purvalanol A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to purvalanol A. Cells stop growing (and may die) at a concentration of purvalanol A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to purvalanol A" EXACT [PomBase:mah] synonym: "sensitive to purvalanol A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to purvalanol A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:20:15Z [Term] id: FYPO:0001693 name: sensitive to reversine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to reversine. Cells stop growing (and may die) at a concentration of reversine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to reversine" EXACT [PomBase:mah] synonym: "sensitive to reversine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to reversine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:22:48Z [Term] id: FYPO:0001694 name: sensitive to hesperadin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hesperadin. Cells stop growing (and may die) at a concentration of hesperadin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hesperadin" EXACT [PomBase:mah] synonym: "sensitive to hesperadin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to hesperadin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:25:02Z [Term] id: FYPO:0001695 name: sensitive to protease inhibitor def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a protease inhibitor. Cells stop growing (and may die) at a concentration of a protease inhibitor that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to protease inhibitor" EXACT [PomBase:mah] synonym: "sensitive to protease inhibitor during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to protease inhibitor during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:28:37Z [Term] id: FYPO:0001696 name: sensitive to protein kinase inhibitor def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a protein kinase inhibitor. Cells stop growing (and may die) at a concentration of a protein kinase inhibitor that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to protein kinase inhibitor" EXACT [PomBase:mah] synonym: "sensitive to protein kinase inhibitor during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to protein kinase inhibitor during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:29:18Z [Term] id: FYPO:0001697 name: sensitive to topoisomerase inhibitor def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a topoisomerase inhibitor. Cells stop growing (and may die) at a concentration of a topoisomerase inhibitor that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to topoisomerase inhibitor" EXACT [PomBase:mah] synonym: "sensitive to topoisomerase inhibitor during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to topoisomerase inhibitor during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:36:04Z [Term] id: FYPO:0001698 name: sensitive to capsazepine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to capsazepine. Cells stop growing (and may die) at a concentration of capsazepine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to capsazepine" EXACT [PomBase:mah] synonym: "sensitive to capsazepine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to capsazepine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:43:31Z [Term] id: FYPO:0001699 name: sensitive to PPT def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol (PPT). Cells stop growing (and may die) at a concentration of PPT that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to PPT" EXACT [PomBase:mah] synonym: "sensitive to 4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol" EXACT [CHEBI:64110] synonym: "sensitive to PPT during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to PPT during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:44:51Z [Term] id: FYPO:0001700 name: sensitive to GW 7647 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to the receptor agonist GW 7647. Cells stop growing (and may die) at a concentration of GW 7647 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to GW 7647" EXACT [PomBase:mah] synonym: "sensitive to GW 7647 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to GW 7647 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:46:27Z [Term] id: FYPO:0001701 name: sensitive to bortezomib def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bortezomib. Cells stop growing (and may die) at a concentration of bortezomib that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bortezomib" EXACT [PomBase:mah] synonym: "sensitive to bortezomib during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to bortezomib during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to Velcade" EXACT [CHEBI:52717] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:56:50Z [Term] id: FYPO:0001702 name: sensitive to nocodazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nocodazole. Cells stop growing (and may die) at a concentration of nocodazole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nocodazole" EXACT [PomBase:mah] synonym: "sensitive to nocodazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nocodazole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-02T16:57:43Z [Term] id: FYPO:0001703 name: normal mitotic cell cycle checkpoint def: "A cell cycle phenotype in which a specific mitotic cell cycle checkpoint is normal (i.e. indistinguishable from wild type). A cell cycle checkpoint controls cell cycle progression by monitoring the timing and integrity of specific cell cycle events." [GO:0000075, GO:0007093, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal cell cycle checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0000137 ! mitotic cell cycle checkpoint phenotype is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2012-11-07T16:00:24Z [Term] id: FYPO:0001704 name: abnormal mitotic cell cycle checkpoint def: "A cell cycle phenotype in which a specific mitotic cell cycle checkpoint is abnormal. A cell cycle checkpoint normally controls cell cycle progression by monitoring the timing and integrity of specific cell cycle events. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions." [GO:0000075, GO:0007093, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal mitotic cell cycle checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0000137 ! mitotic cell cycle checkpoint phenotype is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle created_by: midori creation_date: 2012-11-07T16:03:57Z [Term] id: FYPO:0001705 name: normal mitotic DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type). A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage." [PomBase:mah] synonym: "normal DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint activation" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint activation under non-stressed conditions" NARROW [PomBase:al] synonym: "normal mitotic DNA damage checkpoint during cellular response to DNA damage" EXACT [PomBase:al] synonym: "normal mitotic DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress during vegetative growth is_a: FYPO:0001703 ! normal mitotic cell cycle checkpoint created_by: midori creation_date: 2012-11-07T16:37:55Z [Term] id: FYPO:0001706 name: normal mitotic DNA damage checkpoint during cellular response to ionizing radiation def: "A cell cycle checkpoint phenotype in which any DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ionizing radiation. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage." [PomBase:mah] synonym: "normal DNA damage checkpoint during cellular response to ionizing radiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint activation during cellular response to ionizing radiation" EXACT [PomBase:al] synonym: "normal mitotic DNA damage checkpoint during cellular response to gamma radiation" NARROW [PomBase:al, PomBase:mah] synonym: "normal mitotic DNA damage checkpoint during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint during gamma irradiation" NARROW [PomBase:al] is_a: FYPO:0001705 ! normal mitotic DNA damage checkpoint is_a: FYPO:0001927 ! normal cell cycle regulation during cellular response to ionizing radiation created_by: midori creation_date: 2012-11-07T16:41:15Z [Term] id: FYPO:0001707 name: increased mitotic DNA damage checkpoint activation def: "A cell cycle checkpoint phenotype in which the incidence of mitotic cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type under any specified set of conditions." [PomBase:mah] synonym: "increased mitotic DNA damage checkpoint activation under non-stressed conditions" NARROW [PomBase:al] is_a: FYPO:0000006 ! abnormal mitotic DNA damage checkpoint created_by: midori creation_date: 2012-11-07T16:53:08Z [Term] id: FYPO:0001708 name: normal iron-sulfur cluster binding def: "A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal iron-sulphur cluster binding" EXACT [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-11-08T11:12:40Z [Term] id: FYPO:0001709 name: abnormal iron-sulfur cluster binding def: "A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with an iron-sulfur cluster that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal iron-sulphur cluster binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-11-08T11:24:40Z [Term] id: FYPO:0001710 name: stabilized iron-sulfur cluster binding def: "A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is stabilized, i.e. interactions between the iron-sulfur cluster and the gene product last longer than in wild type under any given set of conditions. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "increased duration of iron-sulfur cluster binding" EXACT [PomBase:mah] synonym: "stabilised iron-sulfur cluster binding" EXACT [PomBase:mah] synonym: "stabilized iron-sulphur cluster binding" EXACT [PomBase:mah] is_a: FYPO:0001709 ! abnormal iron-sulfur cluster binding created_by: midori creation_date: 2012-11-08T11:26:12Z [Term] id: FYPO:0001711 name: destabilized iron-sulfur cluster binding def: "A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is stabilized, i.e. interactions between the iron-sulfur cluster and the gene product do not last as long as in wild type under any given set of conditions. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased duration of iron-sulfur cluster binding" EXACT [PomBase:mah] synonym: "destabilised iron-sulfur cluster binding" EXACT [PomBase:mah] synonym: "destabilized iron-sulphur cluster binding" EXACT [PomBase:mah] is_a: FYPO:0001709 ! abnormal iron-sulfur cluster binding created_by: midori creation_date: 2012-11-08T11:28:03Z [Term] id: FYPO:0001712 name: coenzyme Q10 absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in a cell is too low to detect." [PomBase:mah] synonym: "coenzyme Q10 absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "coenzyme Q10 absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "ubiquinone 10 absent from cell" EXACT [CHEBI:46245] synonym: "UQ-10 absent from cell" EXACT [PomBase:al] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0006978 ! decreased cellular coenzyme Q10 level created_by: midori creation_date: 2012-11-08T13:08:43Z [Term] id: FYPO:0001713 name: abnormal malate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malate into the cell is abnormal." [PomBase:mah] synonym: "abnormal malate import across plasma membrane" EXACT [GO:0098714] synonym: "abnormal malate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal malate import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal malate import into cell" EXACT [PomBase:al] synonym: "abnormal malate uptake" EXACT [PomBase:mah] synonym: "abnormal malic acid import" RELATED [PomBase:al] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-08T13:34:54Z [Term] id: FYPO:0001714 name: decreased malate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malate into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased malate import across plasma membrane" EXACT [GO:0098714] synonym: "decreased malate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased malate import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased malate import into cell" EXACT [PomBase:al] synonym: "decreased malate uptake" EXACT [PomBase:mah] synonym: "decreased malic acid import" RELATED [PomBase:al] synonym: "reduced malate import" EXACT [PomBase:mah] is_a: FYPO:0001713 ! abnormal malate import created_by: midori creation_date: 2012-11-08T13:36:00Z [Term] id: FYPO:0001715 name: abnormal succinate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of succinate into the cell is abnormal." [PomBase:mah] synonym: "abnormal succinate import across plasma membrane" EXACT [GO:0098720] synonym: "abnormal succinate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal succinate import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal succinate import into cell" EXACT [PomBase:al] synonym: "abnormal succinate uptake" EXACT [PomBase:mah] synonym: "abnormal succinic acid import" RELATED [PomBase:al] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-08T13:37:16Z [Term] id: FYPO:0001716 name: decreased succinate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of succinate into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased succinate import across plasma membrane" EXACT [GO:0098720] synonym: "decreased succinate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased succinate import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased succinate import into cell" EXACT [PomBase:al] synonym: "decreased succinate uptake" EXACT [PomBase:mah] synonym: "decreased succinic acid import" RELATED [PomBase:al] synonym: "reduced succinate import" EXACT [PomBase:mah] is_a: FYPO:0001715 ! abnormal succinate import created_by: midori creation_date: 2012-11-08T13:37:23Z [Term] id: FYPO:0001717 name: abnormal malonic acid import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malonic acid into the cell is abnormal." [PomBase:mah] synonym: "abnormal malonate import" RELATED [PomBase:mah] synonym: "abnormal malonic acid import across plasma membrane" EXACT [GO:0098715] synonym: "abnormal malonic acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal malonic acid import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal malonic acid import into cell" EXACT [PomBase:al] synonym: "abnormal malonic acid uptake" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-08T13:39:26Z [Term] id: FYPO:0001718 name: decreased malonic acid import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malonic acid into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased malonate import" RELATED [PomBase:mah] synonym: "decreased malonic acid import across plasma membrane" EXACT [GO:0098715] synonym: "decreased malonic acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased malonic acid import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased malonic acid import into cell" EXACT [PomBase:al] synonym: "decreased malonic acid uptake" EXACT [PomBase:mah] synonym: "reduced malonic acid import" EXACT [PomBase:mah] is_a: FYPO:0001717 ! abnormal malonic acid import created_by: midori creation_date: 2012-11-08T13:39:31Z [Term] id: FYPO:0001719 name: sensitive to lithium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lithium ions. Cells stop growing (and may die) at a concentration of lithium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to lithium" EXACT [PomBase:mah] synonym: "sensitive to lithium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to lithium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to lithium ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-08T13:56:37Z [Term] id: FYPO:0001720 name: abnormal transport def: "A phenotype in which a specific transport process is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000149 ! transport phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2012-11-08T14:01:10Z [Term] id: FYPO:0001721 name: abnormal sodium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular sodium export" EXACT [PomBase:al] synonym: "abnormal sodium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal sodium export during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sodium export from cell" EXACT [PomBase:mah] synonym: "abnormal sodium ion export" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-08T14:14:05Z [Term] id: FYPO:0001722 name: decreased sodium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular sodium export" EXACT [PomBase:al] synonym: "decreased sodium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased sodium export during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sodium export from cell" EXACT [PomBase:mah] synonym: "decreased sodium ion export" EXACT [PomBase:mah] synonym: "reduced sodium export" EXACT [PomBase:mah] is_a: FYPO:0001721 ! abnormal sodium export created_by: midori creation_date: 2012-11-08T14:16:42Z [Term] id: FYPO:0001723 name: ferrichrome absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more ferrichromes measured in a cell is too low to detect." [PomBase:mah] synonym: "ferrichrome absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "ferrichrome absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "siderophore absent from cell" BROAD [PomBase:al] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth created_by: midori creation_date: 2012-11-08T14:29:13Z [Term] id: FYPO:0001724 name: increased GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GTP more than wild type, or that a mutation in one gene increases GTP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0001528 ! abnormal GTP binding created_by: midori creation_date: 2012-11-08T14:35:53Z [Term] id: FYPO:0001725 name: normal cellular aspartate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular aspartate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular aspartate level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular aspartic acid level" RELATED [PomBase:mah] synonym: "normal cellular L-aspartate level" EXACT [PomBase:mah] synonym: "normal level of aspartate in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-11-08T15:11:15Z [Term] id: FYPO:0001726 name: normal cellular cysteine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-cysteine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular cysteine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular cysteine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-cysteine level" EXACT [PomBase:mah] synonym: "normal level of cysteine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-11-08T15:15:16Z [Term] id: FYPO:0001727 name: decreased cellular glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glutamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-glutamine level" EXACT [PomBase:mah] synonym: "decreased level of glutamine in cell" EXACT [PomBase:mah] synonym: "reduced cellular glutamine level" EXACT [PomBase:mah] synonym: "reduced level of glutamine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-11-08T15:16:02Z [Term] id: FYPO:0001728 name: increased cellular serine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-serine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular serine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular serine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased serine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-11-08T15:31:11Z [Term] id: FYPO:0001729 name: normal vacuolar cysteine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-cysteine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of cysteine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar cysteine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuolar cysteine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-cysteine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001726 ! normal cellular cysteine level created_by: midori creation_date: 2012-11-08T15:32:07Z [Term] id: FYPO:0001730 name: increased level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of substance in vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar level of substance" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001601 ! altered level of substance in vacuole created_by: midori creation_date: 2012-11-08T15:33:48Z [Term] id: FYPO:0001731 name: increased vacuolar glutamate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of glutamate in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar glutamate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar glutamic acid level" RELATED [PomBase:mah] synonym: "increased vacuolar L-glutamate level" EXACT [PomBase:mah] is_a: FYPO:0001568 ! increased cellular glutamate level is_a: FYPO:0001730 ! increased level of substance in vacuole created_by: midori creation_date: 2012-11-08T15:35:05Z [Term] id: FYPO:0001732 name: decreased vacuolar glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of glutamine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar glutamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar L-glutamine level" EXACT [PomBase:mah] synonym: "reduced level of glutamine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar glutamine level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001727 ! decreased cellular glutamine level created_by: midori creation_date: 2012-11-08T15:38:07Z [Term] id: FYPO:0001733 name: abnormal mitotic spindle pole body separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body separation is abnormal. Spindle pole body separation is the process in which duplicated spindle pole bodies detach and migrate apart within the nuclear membrane." [PomBase:mah] comment: Also consider annotating to 'monopolar mitotic spindle' (FYPO:0000276) if you observe any monopolar spindles. synonym: "abnormal mitotic SPB separation" EXACT [PomBase:mah] synonym: "abnormal spindle pole body separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle pole body separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2012-11-14T11:49:37Z [Term] id: FYPO:0001734 name: abolished mitotic spindle pole body separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which duplicated mitotic spindle pole bodies do not separate." [PomBase:mah] comment: Also consider annotating to 'monopolar mitotic spindle' (FYPO:0000276) if you observe any monopolar spindles. synonym: "abolished spindle pole body separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "clustered mitotic spindle pole bodies" RELATED [PomBase:al] synonym: "mitotic SPB separation abolished" EXACT [PomBase:mah] synonym: "mitotic spindle pole body separation abolished" EXACT [PomBase:mah] synonym: "spindle pole body separation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001733 ! abnormal mitotic spindle pole body separation created_by: midori creation_date: 2012-11-14T11:49:54Z [Term] id: FYPO:0001735 name: abnormal iron-sulfur cluster transfer def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein is abnormal." [PomBase:mah] synonym: "abnormal iron-sulfur cluster transfer during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal iron-sulfur cluster transfer during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal iron-sulphur cluster transfer" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-11-14T12:03:16Z [Term] id: FYPO:0001736 name: decreased iron-sulfur cluster transfer def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased iron-sulfur cluster transfer during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased iron-sulfur cluster transfer during vegetative growth" EXACT [PomBase:mah] synonym: "decreased iron-sulfur cluster transfer to ferredoxin" NARROW [PomBase:al] synonym: "decreased iron-sulphur cluster transfer" EXACT [PomBase:mah] synonym: "reduced iron-sulfur cluster transfer" EXACT [PomBase:mah] is_a: FYPO:0001735 ! abnormal iron-sulfur cluster transfer created_by: midori creation_date: 2012-11-14T12:03:45Z [Term] id: FYPO:0001737 name: abnormal pantothenate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pantothenate into the cell is abnormal." [PomBase:mah] synonym: "abnormal pantothenate import across plasma membrane" EXACT [GO:0098717] synonym: "abnormal pantothenate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal pantothenate import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal pantothenate import into cell" EXACT [PomBase:al] synonym: "abnormal pantothenate uptake" EXACT [PomBase:mah] synonym: "abnormal pantothenic acid import" RELATED [PomBase:al] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-14T12:23:05Z [Term] id: FYPO:0001738 name: decreased pantothenate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pantothenate into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased pantothenate import across plasma membrane" EXACT [GO:0098717] synonym: "decreased pantothenate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased pantothenate import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pantothenate import into cell" EXACT [PomBase:al] synonym: "decreased pantothenate uptake" EXACT [PomBase:mah] synonym: "decreased pantothenic acid import" RELATED [PomBase:al] synonym: "reduced pantothenate import" EXACT [PomBase:mah] is_a: FYPO:0001737 ! abnormal pantothenate import created_by: midori creation_date: 2012-11-14T12:23:13Z [Term] id: FYPO:0001739 name: increased pantothenate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pantothenate into the cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased pantothenate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased pantothenate import during vegetative growth" EXACT [PomBase:mah] synonym: "increased pantothenate import into cell" EXACT [PomBase:al] synonym: "increased pantothenate uptake" EXACT [PomBase:mah] synonym: "increased pantothenic acid import" RELATED [PomBase:al] is_a: FYPO:0001737 ! abnormal pantothenate import created_by: midori creation_date: 2012-11-14T12:23:34Z [Term] id: FYPO:0001740 name: increased gross chromosomal rearrangement def: "A cell phenotype in which large chromosomal rearrangements occur more frequently than in wild type cells. Chromosomal rearrangements may include deletions, duplications, inversions, and translocations." [http://www.ncbi.nlm.nih.gov/books/NBK21367/, PMID:18923422, PomBase:mah] synonym: "increased occurrence of gross chromosomal rearrangement" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2012-11-14T13:36:27Z [Term] id: FYPO:0001741 name: increased chromosomal translocation def: "A cell phenotype in which chromosomal translocations occur more frequently than in wild type cells. In a chromosomal translocation, chromosome parts are exchanged between non-homologous chromosomes." [PMID:18923422, PomBase:al, PomBase:mah] synonym: "increased occurrence of chromosomal translocation" EXACT [PomBase:mah] is_a: FYPO:0001740 ! increased gross chromosomal rearrangement created_by: midori creation_date: 2012-11-14T14:01:18Z [Term] id: FYPO:0001742 name: increased isochromosome formation def: "A cell phenotype in which isochromosome formation occurs more frequently than in wild type cells. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place." [PMID:18923422, PomBase:al, PomBase:mah] comment: In S. pombe, isochromosome formation is most commonly observed with chromosome 3. synonym: "increased occurrence of isochromosome formation" EXACT [PomBase:mah] is_a: FYPO:0001740 ! increased gross chromosomal rearrangement created_by: midori creation_date: 2012-11-14T14:05:03Z [Term] id: FYPO:0001743 name: increased isochromosome formation with preferential breakage in the imr region def: "A cell phenotype in which isochromosome formation occurs more frequently than in wild type cells, and in which the break point is located in the imr region in the majority of cases. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place." [PMID:18923422, PomBase:al, PomBase:mah] comment: In S. pombe, isochromosome formation is most commonly observed with chromosome 3. When wild type cells form isochromosomes, the break-point is formed half the time in the imr region and half the time in the otr-irc region. synonym: "increased occurrence of isochromosome formation with preferential breakage in the imr region" EXACT [PomBase:mah] is_a: FYPO:0001742 ! increased isochromosome formation created_by: midori creation_date: 2012-11-14T14:11:30Z [Term] id: FYPO:0001744 name: abnormal biotin import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell is abnormal." [PomBase:mah] synonym: "abnormal biotin import across plasma membrane" EXACT [GO:1905135] synonym: "abnormal biotin import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal biotin import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal biotin import into cell" EXACT [PomBase:al] synonym: "abnormal biotin uptake" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-14T14:16:45Z [Term] id: FYPO:0001745 name: increased biotin import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased biotin import across plasma membrane" EXACT [GO:1905135] synonym: "increased biotin import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased biotin import during vegetative growth" EXACT [PomBase:mah] synonym: "increased biotin import into cell" EXACT [PomBase:al] synonym: "increased biotin uptake" EXACT [PomBase:mah] is_a: FYPO:0001744 ! abnormal biotin import created_by: midori creation_date: 2012-11-14T14:17:14Z [Term] id: FYPO:0001746 name: abolished biotin import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell is abolished." [PomBase:mah] synonym: "abolished biotin import across plasma membrane" EXACT [GO:1905135] synonym: "abolished biotin import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished biotin import during vegetative growth" EXACT [PomBase:mah] synonym: "abolished biotin import into cell" EXACT [PomBase:al] synonym: "abolished biotin uptake" EXACT [PomBase:mah] synonym: "absent biotin import" EXACT [PomBase:al] synonym: "biotin import abolished" EXACT [PomBase:mah] is_a: FYPO:0001744 ! abnormal biotin import created_by: midori creation_date: 2012-11-14T14:17:27Z [Term] id: FYPO:0001747 name: abnormal nickel import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of nickel ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular nickel import" EXACT [PomBase:al] synonym: "abnormal nickel cation import" EXACT [PomBase:mah] synonym: "abnormal nickel import across plasma membrane" EXACT [GO:0098716] synonym: "abnormal nickel import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nickel import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nickel import into cell" EXACT [PomBase:mah] synonym: "abnormal nickel ion import" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-14T14:26:34Z [Term] id: FYPO:0001748 name: decreased nickel import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of nickel ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular nickel import" EXACT [PomBase:al] synonym: "decreased nickel cation import" EXACT [PomBase:mah] synonym: "decreased nickel import across plasma membrane" EXACT [GO:0098716] synonym: "decreased nickel import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nickel import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nickel import into cell" EXACT [PomBase:mah] synonym: "decreased nickel ion import" EXACT [PomBase:mah] synonym: "reduced nickel import" EXACT [PomBase:mah] is_a: FYPO:0001747 ! abnormal nickel import created_by: midori creation_date: 2012-11-14T14:26:41Z [Term] id: FYPO:0001749 name: sensitive to tacrolimus during salt stress def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tacrolimus when the cell is subject to salt stress." [PomBase:mah] synonym: "hypersensitive to tacrolimus during salt stress" EXACT [PomBase:mah] synonym: "sensitive to FK506 during salt stress" EXACT [CHEBI:61057, PomBase:mah] synonym: "sensitive to tacrolimus during salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tacrolimus during salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000086 ! sensitive to tacrolimus created_by: midori creation_date: 2012-11-14T14:38:07Z [Term] id: FYPO:0001750 name: abnormal homocitrate synthase activity def: "A molecular function phenotype in which the observed rate of homocitrate synthase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-11-14T14:42:55Z [Term] id: FYPO:0001751 name: increased homocitrate synthase activity def: "A molecular function phenotype in which the observed rate of homocitrate synthase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001750 ! abnormal homocitrate synthase activity created_by: midori creation_date: 2012-11-14T14:43:03Z [Term] id: FYPO:0001752 name: decreased homocitrate synthase activity def: "A molecular function phenotype in which the observed rate of homocitrate synthase activity is decreased." [PomBase:mah] synonym: "reduced homocitrate synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001750 ! abnormal homocitrate synthase activity created_by: midori creation_date: 2012-11-14T14:45:33Z [Term] id: FYPO:0001753 name: normal anaerobic cell population growth def: "A cell population phenotype in which a population of cells grow normally (i.e. indistinguishably from wild type) under anaerobic conditions." [PomBase:mah] synonym: "normal anaerobic growth" BROAD [PomBase:mah] is_a: FYPO:0000047 ! normal cell population growth created_by: midori creation_date: 2012-11-14T14:52:46Z [Term] id: FYPO:0001754 name: growth auxotrophic for lysine and methionine def: "Auxotrophy in which a cell is unable to synthesize lysine or methionine, and therefore requires lysine and methionine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for lysine and methionine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for lysine and methionine during vegetative growth" EXACT [PomBase:mah] synonym: "lysine and methionine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000039 ! growth auxotrophic for lysine is_a: FYPO:0000040 ! growth auxotrophic for methionine created_by: midori creation_date: 2012-11-14T14:54:20Z [Term] id: FYPO:0001755 name: growth auxotrophic for lysine and cysteine def: "Auxotrophy in which a cell is unable to synthesize lysine or cysteine, and therefore requires lysine and cysteine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for lysine and cysteine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for lysine and cysteine during vegetative growth" EXACT [PomBase:mah] synonym: "lysine and cysteine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000037 ! growth auxotrophic for cysteine is_a: FYPO:0000039 ! growth auxotrophic for lysine created_by: midori creation_date: 2012-11-14T14:55:06Z [Term] id: FYPO:0001756 name: abnormal protein phosphatase activity def: "A molecular function phenotype in which the observed rate of protein phosphatase activity is abnormal." [PomBase:mah] synonym: "abnormal phosphoprotein phosphatase activity" EXACT [GO:0004721, PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-11-14T15:02:25Z [Term] id: FYPO:0001757 name: decreased protein phosphatase activity def: "A molecular function phenotype in which the observed rate of a protein phosphatase activity is decreased." [PomBase:mah] synonym: "decreased phosphoprotein phosphatase activity" EXACT [GO:0004721, PomBase:mah] synonym: "reduced protein phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001756 ! abnormal protein phosphatase activity created_by: midori creation_date: 2012-11-14T15:02:37Z [Term] id: FYPO:0001758 name: increased protein phosphatase activity def: "A molecular function phenotype in which the observed rate of a protein phosphatase activity is increased." [PomBase:mah] synonym: "increased phosphoprotein phosphatase activity" EXACT [GO:0004721, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001756 ! abnormal protein phosphatase activity created_by: midori creation_date: 2012-11-14T15:02:48Z [Term] id: FYPO:0001759 name: normal protein phosphatase activity def: "A molecular function phenotype in which the observed rate of a protein phosphatase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal phosphoprotein phosphatase activity" EXACT [GO:0004721] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-11-14T15:03:21Z [Term] id: FYPO:0001760 name: normal cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell separation after cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell separation after cytokinesis following mitosis" EXACT [PomBase:mah] synonym: "normal mitotic cytokinetic cell separation" EXACT [GO:0000920, PomBase:mah] synonym: "normal septum digestion after cytokinesis" EXACT [GO:0000920] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-11-14T15:25:43Z [Term] id: FYPO:0001761 name: normal mitotic G1/S phase transition def: "A cellular process phenotype in which the G1/S transition of the mitotic cell cycle is normal." [PomBase:mah] synonym: "normal cell cycle progression through mitotic G1/S phase transition" EXACT [PomBase:mah] synonym: "normal G1/S phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002741 ! normal mitotic cell cycle process created_by: midori creation_date: 2012-11-14T15:28:02Z [Term] id: FYPO:0001762 name: normal tRNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification, the covalent alteration of one or more nucleotides within a tRNA molecule, is normal (i.e. indistinguishable from wild type)." [GO:0006400, PomBase:mah] synonym: "normal tRNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-11-14T17:09:21Z [Term] id: FYPO:0001763 name: normal tRNA methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA methylation, the posttranscriptional addition of methyl groups to specific residues in a tRNA molecule, is normal (i.e. indistinguishable from wild type)." [GO:0030488, PomBase:mah] synonym: "normal tRNA methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001762 ! normal tRNA modification created_by: midori creation_date: 2012-11-14T17:11:06Z [Term] id: FYPO:0001764 name: normal tRNA-Asp C48, C49, C60, C61 and C62 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C48, C49, C60, C61 and C62 residues in a tRNA-Asp molecule, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal tRNA-Asp C48, C49, C60, C61 and C62 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA-Asp C48, C49, C60, C61 and C62 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal tRNA-Asp methylation on C48, C49, C60, C61 and C62" EXACT [PomBase:mah] is_a: FYPO:0001763 ! normal tRNA methylation created_by: midori creation_date: 2012-11-14T17:12:31Z [Term] id: FYPO:0001765 name: abnormal tRNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification, the covalent alteration of one or more nucleotides within a tRNA molecule, is abnormal." [GO:0006400, PomBase:mah] synonym: "abnormal tRNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tRNA modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2012-11-14T17:16:05Z [Term] id: FYPO:0001766 name: abnormal tRNA methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA methylation, the posttranscriptional addition of methyl groups to specific residues in a tRNA molecule, is abnormal." [GO:0030488, PomBase:mah] synonym: "abnormal tRNA methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tRNA methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001765 ! abnormal tRNA modification created_by: midori creation_date: 2012-11-14T17:16:35Z [Term] id: FYPO:0001767 name: decreased tRNA-Asp C48, C49, C60, C61 and C62 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C48, C49, C60, C61 and C62 residues in a tRNA-Asp molecule, occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased tRNA-Asp C48, C49, C60, C61 and C62 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tRNA-Asp C48, C49, C60, C61 and C62 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tRNA-Asp methylation on C48, C49, C60, C61 and C62" EXACT [PomBase:mah] synonym: "reduced tRNA-Asp C48, C49, C60, C61 and C62 methylation" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2012-11-14T17:17:12Z [Term] id: FYPO:0001768 name: abolished tRNA-Asp C38 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C38 residue in a tRNA-Asp molecule is abolished." [PomBase:mah] synonym: "abolished tRNA-Asp C38 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA-Asp C38 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished tRNA-Asp methylation on C38" EXACT [PomBase:mah] synonym: "tRNA-Asp C38 methylation abolished" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation is_a: FYPO:0008344 ! abolished tRNA modification created_by: midori creation_date: 2012-11-14T17:18:18Z [Term] id: FYPO:0001769 name: increased tRNA-Asp C38 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C38 residue in a tRNA-Asp molecule, occurs to a greater extent than normal." [PomBase:mah] synonym: "increased tRNA-Asp C38 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased tRNA-Asp C38 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased tRNA-Asp methylation on C38" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2012-11-14T17:21:25Z [Term] id: FYPO:0001770 name: normal tRNA methyltransferase activity def: "A molecular function phenotype in which the observed rate of a tRNA methyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-11-14T17:30:11Z [Term] id: FYPO:0001771 name: abnormal tRNA methyltransferase activity def: "A molecular function phenotype in which the observed rate of a tRNA methyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-11-14T17:31:31Z [Term] id: FYPO:0001772 name: decreased tRNA methyltransferase activity def: "A molecular function phenotype in which the observed rate of a tRNA methyltransferase activity is decreased." [PomBase:mah] synonym: "reduced tRNA methyltransferase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001771 ! abnormal tRNA methyltransferase activity created_by: midori creation_date: 2012-11-14T17:31:42Z [Term] id: FYPO:0001773 name: abolished tRNA methyltransferase activity def: "A molecular function phenotype in which a tRNA methyltransferase activity is absent." [PomBase:mah] synonym: "tRNA methyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001771 ! abnormal tRNA methyltransferase activity created_by: midori creation_date: 2012-11-14T17:31:46Z [Term] id: FYPO:0001774 name: abnormal protein localization to eisosome filament def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the eisosome filament is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the eisosome filament and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to eisosome filament" EXACT [PomBase:mah] synonym: "abnormal protein localization to eisosome filament during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to eisosome filament during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to linear eisosome" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-11-21T13:53:15Z [Term] id: FYPO:0001775 name: abolished protein localization to eisosome filament def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the eisosome filament is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to eisosome filament" EXACT [PomBase:mah] synonym: "abolished protein localization to eisosome filament during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to eisosome filament during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to linear eisosome" EXACT [PomBase:mah] synonym: "protein localization to eisosome filament abolished" EXACT [PomBase:mah] is_a: FYPO:0001774 ! abnormal protein localization to eisosome filament created_by: midori creation_date: 2012-11-21T13:55:52Z [Term] id: FYPO:0001776 name: normal protein localization to eisosome filament def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the eisosome filament is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to eisosome filament" EXACT [PomBase:mah] synonym: "normal protein localization to eisosome filament during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to eisosome filament during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to linear eisosome" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2012-11-21T14:04:30Z [Term] id: FYPO:0001777 name: short eisosome filament def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the eisosome filament is shorter than normal." [PomBase:mah] synonym: "decreased eisosome filament length" EXACT [PomBase:mah] synonym: "short eisosome filament during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short eisosome filament during vegetative growth" EXACT [PomBase:mah] synonym: "short linear eisosomes" EXACT [PomBase:al] is_a: FYPO:0007439 ! abnormal eisosome morphology created_by: midori creation_date: 2012-11-21T14:05:30Z [Term] id: FYPO:0001778 name: abnormal centromere localization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of one or more centromere(s) is abnormal." [PomBase:mah] synonym: "abnormal centromere localisation" EXACT [PomBase:mah] synonym: "abnormal centromere localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal centromere localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal kinetochore localization" EXACT [GO:0072765, PomBase:al] is_a: FYPO:0001440 ! abnormal protein complex localization created_by: midori creation_date: 2012-11-21T14:24:28Z [Term] id: FYPO:0001779 name: abnormal centromere clustering at nuclear periphery during vegetative growth alt_id: FYPO:0001780 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is abnormal. Centromere-kinetochore complexes normally cluster near the old spindle pole body during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "abnormal centromere clustering at nuclear periphery during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal centromere clustering at nuclear periphery during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal centromere clustering at old mitotic spindle pole body" RELATED [PomBase:vw] synonym: "abnormal centromere clustering at SPB" RELATED [PomBase:mah] synonym: "abnormal centromere clustering at spindle pole body" RELATED [GO:0072766, PomBase:mah] synonym: "abnormal centromere-SPB clustering" RELATED [GO:0072766] synonym: "abnormal kinetochore clustering at old mitotic spindle pole body" RELATED [PomBase:vw] synonym: "abnormal kinetochore clustering at SPB" RELATED [GO:0072766] synonym: "abnormal kinetochore clustering at spindle pole body" RELATED [PomBase:mah] synonym: "abnormal kinetochore localization at spindle pole body" RELATED [GO:0072766] synonym: "abnormal kinetochores to spindle pole body clustering" RELATED [PomBase:vw] synonym: "abnormal mitotic centromere clustering at nuclear periphery" EXACT [PomBase:vw] synonym: "mislocalized, scattered centromeres" RELATED [PomBase:al] synonym: "unclustered kinetochores" RELATED [PomBase:al] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0007768 ! abnormal heterochromatin tethering at nuclear periphery is_a: FYPO:0008382 ! abnormal chromosome region phenotype during vegetative growth created_by: midori creation_date: 2012-11-21T14:33:41Z [Term] id: FYPO:0001782 name: constricted nucleus def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is constricted in the middle, resembling a figure 8." [PomBase:mah] synonym: "constricted nuclei" EXACT [PomBase:vw] synonym: "constricted nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "constricted nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth created_by: midori creation_date: 2012-11-21T14:49:49Z [Term] id: FYPO:0001783 name: elongated, constricted nucleus def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is longer than normal and is constricted in the middle, resembling a figure 8." [PomBase:mah] synonym: "elongated, constricted nuclei" EXACT [PomBase:vw] synonym: "elongated, constricted nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated, constricted nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "long constricted nucleus" EXACT [PomBase:vw] is_a: FYPO:0000832 ! elongated nucleus during vegetative growth is_a: FYPO:0001782 ! constricted nucleus relationship: has_part FYPO:0000832 ! elongated nucleus during vegetative growth relationship: has_part FYPO:0001782 ! constricted nucleus created_by: midori creation_date: 2012-11-21T14:51:08Z [Term] id: FYPO:0001784 name: excess endoplasmic reticulum membrane present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more endoplasmic reticulum (ER) membrane than normal. Excess ER membranes may form abnormal structures." [PomBase:al, PomBase:mah] synonym: "accumulated endoplasmic reticulum membrane" EXACT [] synonym: "accumulated ER membrane" EXACT [] synonym: "endoplasmic reticulum membrane present in greater amount" EXACT [PomBase:mah] synonym: "excess endoplasmic reticulum membrane present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "excess endoplasmic reticulum membrane present during vegetative growth" EXACT [PomBase:mah] synonym: "excess ER membrane present" EXACT [PomBase:mah] synonym: "increased endoplasmic reticulum membrane proliferation" RELATED [PomBase:mah] synonym: "overdeveloped ER membrane" EXACT [PomBase:al] is_a: FYPO:0000354 ! abnormal endoplasmic reticulum morphology is_a: FYPO:0002652 ! excess intracellular endomembrane system present created_by: midori creation_date: 2012-11-21T14:59:30Z [Term] id: FYPO:0001785 name: abnormal sterol binding def: "A molecular function phenotype in which occurrence of sterol binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a sterol that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal cholesterol binding" NARROW [PomBase:mah] synonym: "abnormal ergosterol binding" NARROW [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-11-21T15:17:31Z [Term] id: FYPO:0001786 name: abolished sterol binding def: "A molecular function phenotype in which sterol binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a sterol that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished cholesterol binding" NARROW [PomBase:mah] synonym: "abolished ergosterol binding" NARROW [PomBase:mah] synonym: "sterol binding abolished" EXACT [PomBase:mah] is_a: FYPO:0001785 ! abnormal sterol binding created_by: midori creation_date: 2012-11-21T15:17:39Z [Term] id: FYPO:0001787 name: normal sterol binding def: "A molecular function phenotype in which occurrence of sterol binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cholesterol binding" NARROW [PomBase:mah] synonym: "normal ergosterol binding" NARROW [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-11-21T15:20:15Z [Term] id: FYPO:0001788 name: normal protein localization to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the cytoplasm is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoplasm" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cytoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2012-11-21T15:36:24Z [Term] id: FYPO:0001789 name: normal protein localization to nucleus during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to oxidative stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during oxidative stress" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during oxidative stress response" EXACT [PomBase:vw] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2012-11-21T15:39:01Z [Term] id: FYPO:0001790 name: normal plasmid loss def: "A cell phenotype in which plasmids are lost at the same frequency as in wild-type cells. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2012-11-21T15:52:33Z [Term] id: FYPO:0001791 name: abnormal mitotic spindle pole body duplication def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body duplication is abnormal." [PomBase:mah] synonym: "abnormal mitotic SPB duplication" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body duplication during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spindle pole body duplication during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-11-21T16:01:35Z [Term] id: FYPO:0001792 name: abolished mitotic spindle pole body duplication def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body duplication does not occur, leaving the cell with a single spindle pole body later in the cell cycle than normal." [PomBase:mah] synonym: "abolished mitotic SPB duplication" EXACT [PomBase:mah] synonym: "abolished mitotic spindle pole body duplication during vegetative growth" EXACT [PomBase:mah] synonym: "abolished spindle pole body duplication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic spindle pole body duplication abolished" EXACT [PomBase:mah] synonym: "single mitotic spindle pole body" RELATED [PomBase:al] is_a: FYPO:0001791 ! abnormal mitotic spindle pole body duplication created_by: midori creation_date: 2012-11-21T16:07:06Z [Term] id: FYPO:0001793 name: resistant to cell wall digestion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell shows increased resistance to conditions that degrade the cell wall." [PomBase:mah] synonym: "resistant to cell wall digestion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistant to cell wall digestion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-11-21T16:14:26Z [Term] id: FYPO:0001794 name: normal RNA level during cellular response to purvalanol A def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to purvalanol A" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to purvalanol A" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to purvalanol A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to purvalanol A during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to purvalanol A" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-11-21T16:19:01Z [Term] id: FYPO:0001795 name: normal growth on purvalanol A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing purvalanol A." [PomBase:mah] synonym: "normal cell population growth in presence of purvalanol A" EXACT [PomBase:mah] synonym: "normal cell population growth on purvalanol A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to purvalanol A" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on purvalanol A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-21T16:22:34Z [Term] id: FYPO:0001796 name: protein mislocalized to centromere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the centromeric region of a chromosome is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at the centromere in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to centromere" EXACT [PomBase:vw] synonym: "protein mislocalised to centromere" EXACT [PomBase:mah] synonym: "protein mislocalised to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to chromosome, centromeric region" EXACT [GO:0000775] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth relationship: output_of FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth created_by: midori creation_date: 2012-11-21T16:25:51Z [Term] id: FYPO:0001797 name: abnormal translation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translation is abnormal. Translation is the synthesis of a protein using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain." [GO:0006412, PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'altered protein level' (FYPO:0000834) or one of its descendants. synonym: "abnormal protein biosynthesis" EXACT [GO:0006412] synonym: "abnormal protein synthesis" EXACT [GO:0006412] synonym: "abnormal translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal translation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000291 ! translation phenotype is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2012-11-21T16:31:14Z [Term] id: FYPO:0001798 name: decreased translation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation is decreased." [PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "decreased protein biosynthesis" EXACT [GO:0006412] synonym: "decreased protein synthesis" EXACT [GO:0006412] synonym: "decreased rate of protein synthesis" NARROW [PomBase:al] synonym: "decreased translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased translation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced translation" EXACT [PomBase:mah] is_a: FYPO:0001797 ! abnormal translation is_a: FYPO:0006549 ! decreased gene expression relationship: has_output FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2012-11-21T16:33:39Z [Term] id: FYPO:0001799 name: cell cycle arrest at mitotic G2/M phase transition during response to DNA damage def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition during a cellular response to DNA damage." [PMID:19366728, PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition during DNA damage" EXACT [PomBase:mah] synonym: "cell cycle arrest in mitotic G2 phase during response to DNA damage" RELATED [PomBase:mah] synonym: "mitotic cell cycle arrest at mitotic G2/M phase transition during response to DNA damage" EXACT [PomBase:mah] synonym: "mitotic G2 phase arrest during response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition created_by: midori creation_date: 2012-11-21T16:40:19Z [Term] id: FYPO:0001800 name: abolished protein localization to cell tip, with protein distributed in plasma membrane or cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished, and the protein is instead detected distributed throughout the plasma membrane and/or cell cortex." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell tip, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "abolished protein localization to cell end, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein distributed in cell cortex" NARROW [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein distributed in cell membrane or cortex" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein distributed in plasma membrane" NARROW [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein distributed in plasma membrane or cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein distributed in plasma membrane or cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cell tip abolished, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] is_a: FYPO:0001585 ! abolished protein localization to cell tip during vegetative growth created_by: midori creation_date: 2012-11-29T10:18:01Z [Term] id: FYPO:0001801 name: obsolete inviable cell at high temperature def: "OBSOLETE. A viability phenotype in which a cell is unable to survive at a high temperature at which wild-type cells survive." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the cell viability term with conditions specified. synonym: "lethal in cell at high temperature" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2012-11-29T10:41:00Z [Term] id: FYPO:0001802 name: obsolete elongated cell during cellular response to caffeine def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer than normal during a cellular response to caffeine." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated cell during cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated cell during cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "elongated in response to caffeine" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2012-11-29T11:18:42Z [Term] id: FYPO:0001803 name: obsolete multiseptate cell during cellular response to caffeine def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has more than one septum apiece during a cellular response to caffeine." [PomBase:mah] synonym: "multiseptate cell during cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiseptate cell during cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "multiseptate in response to caffeine" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2012-11-29T11:20:49Z [Term] id: FYPO:0001804 name: obsolete cell lysis during cellular response to caffeine def: "OBSOLETE. An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during a cellular response to caffeine. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000647. synonym: "cell lysis during cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell lysis during cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "cytolysis during cellular response to caffeine" EXACT [PomBase:mah] synonym: "inviable, lysed cell during cellular response to caffeine" EXACT [PomBase:mah] synonym: "lysed cell in response to caffeine" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0000647 created_by: midori creation_date: 2012-11-29T11:22:54Z [Term] id: FYPO:0001805 name: normal adenine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which adenine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal adenine import across plasma membrane" EXACT [GO:0098702] synonym: "normal adenine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal adenine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal adenine import into cell" EXACT [PomBase:al] synonym: "normal adenine uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-11-29T11:51:44Z [Term] id: FYPO:0001806 name: normal guanine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which guanine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal guanine import across plasma membrane" EXACT [GO:0098710] synonym: "normal guanine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal guanine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal guanine import into cell" EXACT [PomBase:al] synonym: "normal guanine uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-11-29T11:52:06Z [Term] id: FYPO:0001807 name: abnormal adenine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of adenine into the cell is abnormal." [PomBase:mah] synonym: "abnormal adenine import across plasma membrane" EXACT [GO:0098702] synonym: "abnormal adenine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal adenine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal adenine import into cell" EXACT [PomBase:al] synonym: "abnormal adenine uptake" EXACT [PomBase:mah] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-29T11:56:11Z [Term] id: FYPO:0001808 name: decreased adenine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of adenine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased adenine import across plasma membrane" EXACT [GO:0098702] synonym: "decreased adenine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased adenine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased adenine import into cell" EXACT [PomBase:al] synonym: "decreased adenine uptake" EXACT [PomBase:mah] synonym: "reduced adenine import" EXACT [PomBase:mah] is_a: FYPO:0001807 ! abnormal adenine import created_by: midori creation_date: 2012-11-29T11:56:22Z [Term] id: FYPO:0001809 name: abnormal guanine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell is abnormal." [PomBase:mah] synonym: "abnormal guanine import across plasma membrane" EXACT [GO:0098710] synonym: "abnormal guanine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal guanine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal guanine import into cell" EXACT [PomBase:al] synonym: "abnormal guanine uptake" EXACT [PomBase:mah] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-29T11:57:55Z [Term] id: FYPO:0001810 name: decreased guanine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased guanine import across plasma membrane" EXACT [GO:0098710] synonym: "decreased guanine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased guanine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased guanine import into cell" EXACT [PomBase:al] synonym: "decreased guanine uptake" EXACT [PomBase:mah] synonym: "reduced guanine import" EXACT [PomBase:mah] is_a: FYPO:0001809 ! abnormal guanine import created_by: midori creation_date: 2012-11-29T11:58:01Z [Term] id: FYPO:0001811 name: altered 5-phosphoribosyl diphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-phosphoribosyl diphosphate measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal 5-phosphoribosyl diphosphate level" EXACT [PomBase:mah] synonym: "altered 5-O-phosphono-alpha-D-ribofuranosyl diphosphate level" EXACT [CHEBI:17111] synonym: "altered 5-phosphoribosyl diphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered 5-phosphoribosyl diphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular 5-phosphoribosyl diphosphate level" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-11-29T12:03:30Z [Term] id: FYPO:0001812 name: increased 5-phosphoribosyl diphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-phosphoribosyl diphosphate measured in a cell is greater than normal." [PomBase:mah] synonym: "increased 5-O-phosphono-alpha-D-ribofuranosyl diphosphate level" EXACT [CHEBI:17111] synonym: "increased 5-phosphoribosyl diphosphate accumulation" RELATED [PomBase:mah] synonym: "increased 5-phosphoribosyl diphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased 5-phosphoribosyl diphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular 5-phosphoribosyl diphosphate level" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001811 ! altered 5-phosphoribosyl diphosphate level created_by: midori creation_date: 2012-11-29T12:03:40Z [Term] id: FYPO:0001813 name: sensitive to N-methyl-N'-nitro-N-nitrosoguanidine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-methyl-N'-nitro-N-nitrosoguanidine. Cells stop growing (and may die) at a concentration of N-methyl-N'-nitro-N-nitrosoguanidine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to N-methyl-N'-nitro-N-nitrosoguanidine" EXACT [PomBase:mah] synonym: "sensitive to MNNG" EXACT [CHEBI:21759] synonym: "sensitive to N-methyl-N'-nitro-N-nitrosoguanidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to N-methyl-N'-nitro-N-nitrosoguanidine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to nitrosoguanidine" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-29T12:47:51Z [Term] id: FYPO:0001814 name: normal cell population growth during iron starvation def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) under iron starvation conditions." [PomBase:mah] synonym: "normal cell population growth during iron depletion" EXACT [PomBase:vw] synonym: "normal cell population growth during iron deprivation" EXACT [PomBase:vw] synonym: "normal growth during iron starvation" BROAD [PomBase:mah] is_a: FYPO:0000047 ! normal cell population growth created_by: midori creation_date: 2012-11-29T13:50:46Z [Term] id: FYPO:0001815 name: increased level of Okazaki fragments def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which Okazaki fragments, the DNA segments produced by discontinuous synthesis of the lagging strand during DNA replication, are present at greater levels than normal." [PomBase:mah] synonym: "accumulation of Okazaki fragments" EXACT [PomBase:mah] synonym: "accumulation of Okazaki fragments during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of Okazaki fragments during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of Okazaki fragments during vegetative growth" EXACT [PomBase:mah] synonym: "Okazaki fragment accumulation" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-11-29T14:28:40Z [Term] id: FYPO:0001816 name: abnormal phosphoribosylamine-glycine ligase activity def: "A molecular function phenotype in which the observed rate of phosphoribosylamine-glycine ligase activity is abnormal." [PomBase:mah] synonym: "abnormal GAR synthetase activity" EXACT [GO:0004637] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-11-29T14:32:55Z [Term] id: FYPO:0001817 name: abolished phosphoribosylamine-glycine ligase activity def: "A molecular function phenotype in which phosphoribosylamine-glycine ligase activity is absent." [PomBase:mah] synonym: "abolished GAR synthetase activity" EXACT [GO:0004637] synonym: "phosphoribosylamine-glycine ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001816 ! abnormal phosphoribosylamine-glycine ligase activity created_by: midori creation_date: 2012-11-29T14:33:03Z [Term] id: FYPO:0001818 name: abnormal phosphoribosylformylglycinamidine cyclo-ligase activity def: "A molecular function phenotype in which the observed rate of phosphoribosylformylglycinamidine cyclo-ligase activity is abnormal." [PomBase:mah] synonym: "abnormal AIR synthase activity" EXACT [GO:0004641] synonym: "abnormal AIR synthetase activity" EXACT [GO:0004641] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-11-08T13:54:28Z [Term] id: FYPO:0001819 name: abolished phosphoribosylformylglycinamidine cyclo-ligase activity def: "A molecular function phenotype in which phosphoribosylformylglycinamidine cyclo-ligase activity is absent." [PomBase:mah] synonym: "abolished AIR synthase activity" EXACT [GO:0004641] synonym: "abolished AIR synthetase activity" EXACT [GO:0004641] synonym: "phosphoribosylformylglycinamidine cyclo-ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001818 ! abnormal phosphoribosylformylglycinamidine cyclo-ligase activity created_by: midori creation_date: 2013-11-08T13:54:35Z [Term] id: FYPO:0001820 name: normal growth on lithium def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing lithium ions." [PomBase:mah] synonym: "normal cell population growth in presence of lithium ions" EXACT [PomBase:mah] synonym: "normal cell population growth on lithium" EXACT [PomBase:mah] synonym: "normal cell population growth on lithium ion" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to lithium ion" RELATED [PomBase:mah] synonym: "normal growth on lithium ion" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on lithium ion" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-29T14:51:06Z [Term] id: FYPO:0001821 name: increased number of heterothallic h+ cells def: "A cell population phenotype in which a greater than normal number of cells in an originally homothallic (h90) population express P-specific information from the mat1 locus." [PomBase:al] synonym: "increased amount of heterothallic H+ cells" EXACT [PomBase:al] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-11-29T14:56:17Z [Term] id: FYPO:0001822 name: mating cassette duplication def: "A cell phenotype in which one or more of the mating cassettes is duplicated." [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2012-11-29T15:05:18Z [Term] id: FYPO:0001823 name: sensitive to chlorpromazine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chlorpromazine. Cells stop growing (and may die) at a concentration of chlorpromazine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to chlorpromazine" EXACT [PomBase:mah] synonym: "sensitive to chlorpromazine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to chlorpromazine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-29T15:16:28Z [Term] id: FYPO:0001824 name: sensitive to trifluoperazine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trifluoperazine. Cells stop growing (and may die) at a concentration of trifluoperazine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to trifluoperazine" EXACT [PomBase:mah] synonym: "sensitive to trifluoperazine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to trifluoperazine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-11-29T15:16:45Z [Term] id: FYPO:0001825 name: increased sodium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased cellular sodium export" EXACT [PomBase:al] synonym: "increased sodium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased sodium export during vegetative growth" EXACT [PomBase:mah] synonym: "increased sodium export from cell" EXACT [PomBase:mah] synonym: "increased sodium ion export" EXACT [PomBase:mah] is_a: FYPO:0001721 ! abnormal sodium export created_by: midori creation_date: 2012-11-29T15:25:30Z [Term] id: FYPO:0001826 name: abolished sodium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell does not occur." [PomBase:mah] synonym: "abolished sodium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished sodium export from cell" EXACT [PomBase:mah] synonym: "abolished sodium ion export" EXACT [PomBase:mah] synonym: "sodium export abolished" EXACT [PomBase:mah] synonym: "sodium export abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001721 ! abnormal sodium export created_by: midori creation_date: 2012-11-29T15:26:28Z [Term] id: FYPO:0001827 name: abnormal glucose import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glucose into the cell is abnormal." [PomBase:mah] synonym: "abnormal glucose import across plasma membrane" EXACT [GO:0098708] synonym: "abnormal glucose import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal glucose import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal glucose import into cell" EXACT [PomBase:al] synonym: "abnormal glucose uptake" EXACT [PomBase:mah] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-11-29T15:31:47Z [Term] id: FYPO:0001828 name: abolished glucose import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell does not occur." [PomBase:mah] synonym: "abolished glucose import across plasma membrane" EXACT [GO:0098708] synonym: "abolished glucose import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished glucose import during vegetative growth" EXACT [PomBase:mah] synonym: "abolished glucose import into cell" EXACT [PomBase:al] synonym: "abolished glucose uptake" EXACT [PomBase:mah] synonym: "glucose import abolished" EXACT [PomBase:mah] is_a: FYPO:0001827 ! abnormal glucose import created_by: midori creation_date: 2012-11-29T15:31:54Z [Term] id: FYPO:0001829 name: normal growth on gluconate carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing gluconate as the carbon source." [PomBase:mah] synonym: "normal cell population growth on gluconate carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on gluconate carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-11-29T15:40:50Z [Term] id: FYPO:0001830 name: decreased cell population growth on gluconate carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing gluconate as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on gluconate carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on gluconate carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on gluconate carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on gluconate carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-11-29T15:45:12Z [Term] id: FYPO:0001831 name: abnormal phosphoglycerate mutase activity def: "A molecular function phenotype in which the observed rate of phosphoglycerate mutase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-11-29T15:47:47Z [Term] id: FYPO:0001832 name: abolished phosphoglycerate mutase activity def: "A molecular function phenotype in which phosphoglycerate mutase activity is absent." [PomBase:mah] synonym: "phosphoglycerate mutase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001831 ! abnormal phosphoglycerate mutase activity created_by: midori creation_date: 2012-11-29T15:48:02Z [Term] id: FYPO:0001833 name: increased phosphoglycerate mutase activity def: "A molecular function phenotype in which the observed rate of phosphoglycerate mutase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001831 ! abnormal phosphoglycerate mutase activity created_by: midori creation_date: 2012-11-29T15:48:26Z [Term] id: FYPO:0001834 name: normal phosphoglycerate mutase activity def: "A molecular function phenotype in which the observed rate of phosphoglycerate mutase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-11-29T15:50:29Z [Term] id: FYPO:0001835 name: normal growth on acidic medium def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium that is more acidic than standard fission yeast media (about 5.8)." [PomBase:mah] synonym: "normal cell population growth on acidic medium" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to acidity" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on acidic medium" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-12-12T18:04:19Z [Term] id: FYPO:0001836 name: normal protein localization to spindle pole body def: "A cell phenotype in which the localization of a protein to the spindle pole body is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to spindle pole body" EXACT [PomBase:mah] synonym: "normal protein localization to SPB" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2012-12-06T15:30:01Z [Term] id: FYPO:0001837 name: increased duration of protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle pole body for a longer time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "increased duration of protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "increased duration of protein localization to mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein localization to mitotic spindle pole body" EXACT [PomBase:vw] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body created_by: midori creation_date: 2012-12-06T15:31:27Z [Term] id: FYPO:0001838 name: decreased protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000775 ! abnormal protein phosphorylation during vegetative growth is_a: FYPO:0002679 ! decreased protein phosphorylation created_by: midori creation_date: 2012-12-06T15:37:32Z [Term] id: FYPO:0001839 name: normal minichromosome loss def: "A cell phenotype in which minichromosomes are lost at the same frequency as in wild-type cells. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PomBase:mah] comment: In fission yeast, a minichromosome is a large portion of a chromosome, usually about half of chromosome 3, that replicates and segregates autonomously. For smaller autonomously replicating and segregating constructs, consider 'normal plasmid loss' (FYPO:0001790). is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2012-12-06T16:04:43Z [Term] id: FYPO:0001840 name: increased minichromosome loss during vegetative growth def: "A cell phenotype in which minichromosomes are lost at a higher frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PomBase:mah] comment: Note that in budding yeast, increased plasmid loss is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. In fission yeast, a minichromosome is a large portion of a chromosome, usually about half of chromosome 3, that replicates and segregates autonomously. For smaller autonomously replicating and segregating constructs, consider 'increased plasmid loss' (FYPO:0000786). synonym: "increased minichromosome loss during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype is_a: FYPO:0001859 ! increased minichromosome loss created_by: midori creation_date: 2012-12-06T16:08:24Z [Term] id: FYPO:0001841 name: abnormal adenylyl cyclase activity def: "A molecular function phenotype in which the observed rate of adenylyl cyclase activity is abnormal." [PomBase:mah] synonym: "abnormal adenylate cyclase activity" EXACT [GO:0004016] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-12-06T16:11:23Z [Term] id: FYPO:0001842 name: increased adenylyl cyclase activity def: "A molecular function phenotype in which the observed rate of adenylyl cyclase activity is increased." [PomBase:mah] synonym: "increased adenylate cyclase activity" EXACT [GO:0004016] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001841 ! abnormal adenylyl cyclase activity created_by: midori creation_date: 2012-12-06T16:11:34Z [Term] id: FYPO:0001843 name: sensitive to rhizoxin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rhizoxin. Cells stop growing (and may die) at a concentration of rhizoxin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to rhizoxin" EXACT [PomBase:mah] synonym: "sensitive to rhizoxin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to rhizoxin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-12-13T12:08:25Z [Term] id: FYPO:0001844 name: sensitive to ansamitocin P-3 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ansamitocin P-3. Cells stop growing (and may die) at a concentration of ansamitocin P-3 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to ansamitocin P-3" EXACT [PomBase:mah] synonym: "sensitive to ansamitocin P-3 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ansamitocin P-3 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2012-12-13T12:20:43Z [Term] id: FYPO:0001845 name: normal kinetochore organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore organization is normal (i.e. indistinguishable from wild type). Kinetochore organization is the assembly, arrangement of constituent parts, or disassembly of kinetochores and their associated proteins." [GO:0051383, PomBase:mah] synonym: "normal kinetochore organisation" EXACT [PomBase:mah] synonym: "normal kinetochore organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal kinetochore organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-12-18T12:05:03Z [Term] id: FYPO:0001846 name: increased duration of mitotic anaphase A def: "A cellular process phenotype in which the duration of progression through anaphase A of mitosis is longer than normal. Anaphase A is the mitotic cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [GO:0000091, PomBase:mah] synonym: "delayed mitotic anaphase A progression" RELATED [PomBase:mah] synonym: "increased duration of anaphase A during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase A during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase A progression" EXACT [PomBase:mah] synonym: "prolonged mitotic anaphase A" EXACT [PomBase:mah] is_a: FYPO:0000618 ! increased duration of mitotic anaphase created_by: midori creation_date: 2012-12-18T12:10:55Z [Term] id: FYPO:0001847 name: abnormal ferric-chelate reductase activity def: "A molecular function phenotype in which the observed rate of ferric-chelate reductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-12-18T13:35:13Z [Term] id: FYPO:0001848 name: abolished ferric-chelate reductase activity def: "A molecular function phenotype in which ferric-chelate reductase activity is absent." [PomBase:mah] synonym: "ferric-chelate reductase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001847 ! abnormal ferric-chelate reductase activity created_by: midori creation_date: 2012-12-18T13:35:24Z [Term] id: FYPO:0001849 name: abnormal ferric iron import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferric iron ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular ferric iron import" EXACT [PomBase:al] synonym: "abnormal ferric ion import" EXACT [PomBase:mah] synonym: "abnormal ferric ion import across plasma membrane" EXACT [GO:0098706] synonym: "abnormal ferric iron import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ferric iron import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ferric iron import into cell" EXACT [PomBase:mah] synonym: "abnormal ferric iron ion import" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-12-18T13:37:37Z [Term] id: FYPO:0001850 name: decreased ferric iron import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferric iron ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular ferric iron import" EXACT [PomBase:al] synonym: "decreased ferric ion import" EXACT [PomBase:mah] synonym: "decreased ferric ion import across plasma membrane" EXACT [GO:0098706] synonym: "decreased ferric iron import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ferric iron import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ferric iron import into cell" NARROW [PomBase:mah] synonym: "decreased ferric iron ion import" EXACT [PomBase:mah] synonym: "reduced ferric iron import" EXACT [PomBase:mah] is_a: FYPO:0001849 ! abnormal ferric iron import created_by: midori creation_date: 2012-12-18T13:37:47Z [Term] id: FYPO:0001851 name: normal ferrous iron import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ferrous iron import is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal ferrous ion import" EXACT [PomBase:mah] synonym: "normal ferrous ion import across plasma membrane" EXACT [GO:0098711] synonym: "normal ferrous iron import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal ferrous iron import during vegetative growth" EXACT [PomBase:mah] synonym: "normal ferrous iron import into cell" EXACT [PomBase:al] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-12-18T13:57:53Z [Term] id: FYPO:0001852 name: decreased transcription during iron starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal when the cell is subject to iron ion starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). synonym: "decreased transcription during iron depletion" EXACT [PomBase:vw] synonym: "decreased transcription during iron deprivation" EXACT [PomBase:vw] synonym: "decreased transcription during iron ion starvation" EXACT [PomBase:mah] synonym: "decreased transcription during iron starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription during iron starvation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription during iron starvation" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth relationship: has_output FYPO:0002042 ! decreased RNA level during cellular response to iron ion starvation created_by: midori creation_date: 2012-12-18T14:13:16Z [Term] id: FYPO:0001853 name: abolished transcription during iron starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription does not occur when the cell is subject to iron ion starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "abolished transcription during iron depletion" EXACT [PomBase:vw] synonym: "abolished transcription during iron deprivation" EXACT [PomBase:vw] synonym: "abolished transcription during iron ion starvation" EXACT [PomBase:mah] synonym: "abolished transcription during iron starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished transcription during iron starvation during vegetative growth" EXACT [PomBase:mah] synonym: "transcription abolished during iron starvation" EXACT [PomBase:mah] is_a: FYPO:0001443 ! abolished transcription during vegetative growth is_a: FYPO:0001852 ! decreased transcription during iron starvation created_by: midori creation_date: 2012-12-18T14:13:28Z [Term] id: FYPO:0001854 name: increased transcription during cellular response to iron def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to iron ions. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased transcription during cellular response to iron during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription during cellular response to iron during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription during cellular response to iron ion" EXACT [PomBase:mah] synonym: "increased transcription during cellular response to iron ions" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2012-12-18T14:20:09Z [Term] id: FYPO:0001855 name: normal transcription during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription, DNA-dependent, during vegetative growth" EXACT [GO:0006351, PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0002882 ! normal transcription created_by: midori creation_date: 2012-12-18T14:22:58Z [Term] id: FYPO:0001856 name: normal transcription during iron starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent when the cell is subject to iron ion starvation. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during iron depletion" EXACT [PomBase:vw] synonym: "normal transcription during iron deprivation" EXACT [PomBase:vw] synonym: "normal transcription during iron ion starvation" EXACT [PomBase:mah] synonym: "normal transcription during iron starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during iron starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2012-12-18T14:25:24Z [Term] id: FYPO:0001857 name: normal transcription during cellular response to iron def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to iron ions. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to iron during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to iron during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription during cellular response to iron ion" EXACT [PomBase:mah] synonym: "normal transcription during cellular response to iron ions" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2012-12-18T14:26:34Z [Term] id: FYPO:0001858 name: increased fatty acid synthase activity def: "A molecular function phenotype in which the observed rate of fatty acid synthase activity is increased." [PomBase:mah] synonym: "increased FAS activity" EXACT [PomBase:al, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000720 ! abnormal fatty acid synthase activity created_by: midori creation_date: 2012-12-18T14:33:31Z [Term] id: FYPO:0001859 name: increased minichromosome loss def: "A cell phenotype in which minichromosomes are lost at a higher frequency than normal. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PomBase:mah] comment: Note that in budding yeast, increased plasmid loss is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. In fission yeast, a minichromosome is a large portion of a chromosome, usually about half of chromosome 3, that replicates and segregates autonomously. For smaller autonomously replicating and segregating constructs, consider 'increased plasmid loss' (FYPO:0000786). synonym: "minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2012-12-18T14:36:26Z [Term] id: FYPO:0001860 name: increased minichromosome loss during meiotic cell cycle def: "A cell phenotype in which minichromosomes are lost at a higher frequency than normal during the meiotic cell cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PomBase:mah] synonym: "increased minichromosome loss during meiosis" RELATED [PomBase:mah] synonym: "meiotic minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0001859 ! increased minichromosome loss created_by: midori creation_date: 2012-12-18T14:43:49Z [Term] id: FYPO:0001861 name: increased minichromosome loss upon segregation during vegetative growth def: "A cell phenotype in which minichromosomes are lost due to abnormal mitotic sister chromatid segregation at a higher frequency than normal." [PomBase:mah] comment: Use this term if the assay to detect minichromosome loss can distinguish a segregation defect from a replication defect (e.g. by microscopy). Note that in budding yeast, increased plasmid loss is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. In fission yeast, a minichromosome is a large portion of a chromosome, usually about half of chromosome 3, that replicates and segregates autonomously. For smaller autonomously replicating and segregating constructs, consider 'increased plasmid loss' (FYPO:0000786). synonym: "increased plasmid loss upon segregation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0001840 ! increased minichromosome loss during vegetative growth relationship: output_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2012-12-18T14:45:41Z [Term] id: FYPO:0001862 name: increased minichromosome loss upon segregation during meiotic cell cycle def: "A cell phenotype in which minichromosomes are lost due to abnormal meiotic chromosome segregation at a higher frequency than normal." [PomBase:mah] comment: Use this term if the assay to detect minichromosome loss can distinguish a segregation defect from a replication defect (e.g. by microscopy). Note that in budding yeast, increased plasmid loss is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. In fission yeast, a minichromosome is a large portion of a chromosome, usually about half of chromosome 3, that replicates and segregates autonomously. For smaller autonomously replicating and segregating constructs, consider 'increased plasmid loss' (FYPO:0000786). synonym: "increased plasmid loss upon segregation during meiosis" RELATED [PomBase:mah] synonym: "meiotic minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0001860 ! increased minichromosome loss during meiotic cell cycle relationship: output_of FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2012-12-18T14:55:41Z [Term] id: FYPO:0001863 name: abolished leptomycin B binding def: "A molecular function phenotype in which leptomycin B binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished LMB binding" EXACT [PomBase:al] synonym: "leptomycin B binding abolished" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-12-18T15:04:38Z [Term] id: FYPO:0001864 name: mating without glucose starvation def: "A cellular process phenotype in which conjugation takes place in cells that are not subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "conjugation without glucose starvation" EXACT [PomBase:mah] synonym: "mating in the absence of glucose starvation" EXACT [PomBase:al] synonym: "mating without glucose depletion" EXACT [PomBase:vw] synonym: "mating without glucose deprivation" EXACT [PomBase:vw] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2012-12-18T15:35:33Z [Term] id: FYPO:0001865 name: normal negative regulation of transcription by glucose def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) is normal. Transcription of specific genes is repressed in the presence of glucose, as in wild type." [GO:0045014, PomBase:mah] synonym: "normal glucose repression" EXACT [GO:0045014, PomBase:mah] synonym: "normal glucose repression during vegetative growth" EXACT [PomBase:mah] synonym: "normal glucose-sensitive transcription" RELATED [PomBase:vw] synonym: "normal negative regulation of transcription by glucose during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal negative regulation of transcription by glucose during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2013-01-09T15:24:17Z [Term] id: FYPO:0001866 name: normal adenylyl cyclase activity def: "A molecular function phenotype in which the observed rate of adenylyl cyclase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal adenylate cyclase activity" EXACT [GO:0004016] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2013-01-09T15:30:04Z [Term] id: FYPO:0001867 name: increased shmoo formation def: "A cellular process phenotype in which the occurrence of mating projection assembly is increased." [PomBase:mah] synonym: "increased conjugation tube formation" EXACT [PMID:1905818, PomBase:mah] synonym: "increased mating projection assembly" EXACT [PomBase:mah] synonym: "increased mating projection formation" EXACT [PomBase:mah] synonym: "increased shmoo assembly" EXACT [PomBase:mah] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2013-01-28T13:42:55Z [Term] id: FYPO:0001868 name: decreased adenylyl cyclase activity def: "A molecular function phenotype in which the observed rate of adenylyl cyclase activity is decreased." [PomBase:mah] synonym: "decreased adenylate cyclase activity" EXACT [GO:0004016] synonym: "reduced adenylyl cyclase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001841 ! abnormal adenylyl cyclase activity created_by: midori creation_date: 2013-01-09T15:32:06Z [Term] id: FYPO:0001869 name: abolished adenylyl cyclase activity def: "A molecular function phenotype in which adenylyl cyclase activity is absent." [PomBase:mah] synonym: "abolished adenylate cyclase activity" EXACT [GO:0004016] synonym: "adenylyl cyclase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001841 ! abnormal adenylyl cyclase activity created_by: midori creation_date: 2013-01-09T15:32:19Z [Term] id: FYPO:0001870 name: normal centromere clustering at nuclear periphery during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is normal (i.e. indistinguishable from wild type). Centromere-kinetochore complexes normally cluster near the old spindle pole body during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal centromere clustering at nuclear periphery during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal centromere clustering at nuclear periphery during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal centromere clustering at SPB" RELATED [PomBase:mah] synonym: "normal centromere clustering at spindle pole body" RELATED [GO:0072766, PomBase:mah] synonym: "normal centromere-SPB clustering" RELATED [GO:0072766] synonym: "normal kinetochore clustering at SPB" RELATED [GO:0072766] synonym: "normal kinetochore clustering at spindle pole body" RELATED [PomBase:mah] synonym: "normal kinetochore localization at spindle pole body" RELATED [GO:0072766] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0008381 ! chromosome region localization phenotype during vegetative growth created_by: midori creation_date: 2013-01-09T15:36:22Z [Term] id: FYPO:0001871 name: increased agglutination def: "A cell adhesion phenotype in which cells adhere to other cells of compatible mating type more strongly or to a greater extent than normal." [PomBase:mah] synonym: "increased agglutination involved in conjugation with cellular fusion" EXACT [GO:0000752] is_a: FYPO:0001872 ! abnormal cell adhesion created_by: midori creation_date: 2013-01-09T15:41:12Z [Term] id: FYPO:0001872 name: abnormal cell adhesion def: "A cellular process phenotype in which adhesion of a cell to a substrate or another cell is abnormal." [PomBase:mah] synonym: "adhesion defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2013-01-09T15:42:54Z [Term] id: FYPO:0001873 name: shmoo formation in absence of opposite mating type def: "A cellular process phenotype in which mating projection assembly takes place despite the absence of cells of the opposite mating type." [PMID:1905818, PomBase:mah] comment: The difference between this term and FYPO:0006010 is that the former describes shmoo formation when no compatible cells are present, whereas the latter describes failure to make contact with available cells of the opposite mating type. synonym: "conjugation tube formation in absence of opposite mating type" RELATED [PMID:1905818, PomBase:mah] synonym: "mating projection assembly in absence of opposite mating type" EXACT [PomBase:mah] synonym: "mating projection formation in absence of opposite mating type" EXACT [PomBase:mah] synonym: "shmoo without partner cell" BROAD [PomBase:mah] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2013-01-28T13:48:16Z [Term] id: FYPO:0001874 name: abnormal asymmetric protein localization, with protein localized to both mitotic spindle pole bodies def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the preferential localization of a protein to either the old or new spindle pole body is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal asymmetric protein localisation to old or new mitotic spindle pole body" EXACT [PomBase:mah] synonym: "abnormal asymmetric protein localization to old or new mitotic SPB" EXACT [PomBase:mah] synonym: "abnormal asymmetric protein localization to old or new mitotic spindle pole body" EXACT [] synonym: "abnormal asymmetric protein localization to old or new mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal asymmetric protein localization to old or new mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal occurrence of normally asymmetric protein localization to old or new mitotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body created_by: midori creation_date: 2013-01-30T11:45:04Z [Term] id: FYPO:0001875 name: decreased asymmetric protein localization, with protein localized to both mitotic spindle pole bodies def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the preferential localization of a protein to either the old or new spindle pole body is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased asymmetric protein localisation to old or new mitotic spindle pole body" EXACT [PomBase:mah] synonym: "decreased asymmetric protein localization to old or new mitotic SPB" EXACT [PomBase:mah] synonym: "decreased asymmetric protein localization to old or new mitotic spindle pole body" EXACT [] synonym: "decreased asymmetric protein localization to old or new mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased asymmetric protein localization to old or new mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "decreased occurrence of normally asymmetric protein localization to old or new mitotic spindle pole body" EXACT [PomBase:mah] synonym: "reduced asymmetric protein localization to old or new mitotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0001874 ! abnormal asymmetric protein localization, with protein localized to both mitotic spindle pole bodies created_by: midori creation_date: 2013-01-30T11:46:48Z [Term] id: FYPO:0001876 name: decreased asymmetric protein localization, with protein localized to both mitotic spindle pole bodies during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the preferential localization of a protein to either the old or new spindle pole body is decreased during mitotic anaphase, and the protein is instead symmetrically localized to both SPBs." [PMID:22119525, PMID:22419817, PMID:24920823, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormally symmetric protein localization to mitotic SPB during anaphase" EXACT [PomBase:mah] synonym: "abnormally symmetric protein localization to mitotic spindle pole bodies during anaphase" EXACT [PomBase:mah] synonym: "abnormally symmetric protein localization to spindle pole bodies during mitotic anaphase" EXACT [PomBase:mah] synonym: "abolished asymmetric protein localization to old or new mitotic SPB" RELATED [PomBase:mah] synonym: "decreased asymmetric protein localisation to old or new mitotic spindle pole body during anaphase, with protein symmetrically localised to both spindle pole bodies" EXACT [PomBase:mah] synonym: "decreased asymmetric protein localization to old or new mitotic spindle pole body during anaphase, with protein symmetrically localized to both spindle pole bodies" EXACT [] synonym: "decreased asymmetric protein localization to old or new mitotic spindle pole body during anaphase, with protein symmetrically localized to both spindle pole bodies, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased asymmetric protein localization to old or new mitotic spindle pole body during mitotic anaphase, with protein symmetrically localized to both spindle pole bodies" EXACT [PomBase:mah] synonym: "reduced asymmetric protein localization to old or new mitotic spindle pole body during anaphase, with protein symmetrically localized to both spindle pole bodies" EXACT [PomBase:mah] is_a: FYPO:0001875 ! decreased asymmetric protein localization, with protein localized to both mitotic spindle pole bodies created_by: midori creation_date: 2013-01-30T11:47:20Z [Term] id: FYPO:0001877 name: viable thin vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable but has an abnormally low thickness or diameter." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "thin viable vegetative cell" EXACT [PomBase:mah] synonym: "viable thin cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable thin vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable vegetative cell with decreased cell diameter" EXACT [PomBase:mah] synonym: "viable vegetative cell with decreased cell thickness" EXACT [PomBase:mah] synonym: "viable vegetative cell with decreased cell width" EXACT [PomBase:mah] is_a: FYPO:0001879 ! thin cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape relationship: has_part FYPO:0001879 ! thin cell created_by: midori creation_date: 2013-01-30T12:02:41Z [Term] id: FYPO:0001878 name: viable thin, elongated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable but is elongated and has an abnormally low thickness or diameter." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "thin, elongated viable cell during vegetative growth" EXACT [PomBase:mah] synonym: "thin, elongated viable vegetative cell" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell with decreased cell diameter" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell with decreased cell thickness" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell with decreased cell width" EXACT [PomBase:mah] synonym: "viable thin, elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell is_a: FYPO:0001877 ! viable thin vegetative cell created_by: midori creation_date: 2013-01-30T12:05:15Z [Term] id: FYPO:0001879 name: thin cell def: "A cell morphology phenotype in which a cell has a smaller diameter (thickness; width) than normal." [PomBase:mah] synonym: "decreased cell diameter" EXACT [PomBase:mah] synonym: "decreased cell thickness" EXACT [PomBase:mah] synonym: "decreased cell width" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape is_a: FYPO:0001127 ! abnormal cell size created_by: midori creation_date: 2013-01-30T12:06:48Z [Term] id: FYPO:0001880 name: abolished protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell division site" EXACT [PomBase:mah] synonym: "abolished protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein recruitment to cell division site" RELATED [PomBase:vw] synonym: "protein localization to cell division site abolished" EXACT [PomBase:mah] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2013-01-30T12:18:16Z [Term] id: FYPO:0001881 name: elongated actin filaments def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin filaments that are longer than normal." [PomBase:mah] synonym: "elongated actin filaments during mitotic cell cycle" EXACT [PomBase:mah] synonym: "elongated actin filaments during vegetative growth" EXACT [PomBase:mah] synonym: "elongated microfilaments" RELATED [PomBase:mah] synonym: "increased actin filament length during vegetative growth" EXACT [] synonym: "long actin filaments during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology during vegetative growth created_by: midori creation_date: 2013-01-30T12:21:19Z [Term] id: FYPO:0001882 name: resistance to cell wall-degrading enzymes def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of one or more enzymes that degrades cell wall polysaccharides than normal." [PomBase:mah] synonym: "resistance to cell wall-degrading enzymes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cell wall-degrading enzymes during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to Lyticase" NARROW [PomBase:mah] synonym: "resistance to Novozyme 234" NARROW [PomBase:mah] synonym: "resistance to Zymolyase" NARROW [PomBase:mah] synonym: "resistant to cell wall-degrading enzymes" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-01-30T12:30:20Z [Term] id: FYPO:0001883 name: normal growth on caspofungin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing caspofungin." [PomBase:mah] synonym: "normal cell population growth in presence of caspofungin" EXACT [PomBase:mah] synonym: "normal cell population growth on caspofungin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on glucan synthase inhibitor" BROAD [PomBase:mah] synonym: "normal cellular response to caspofungin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on caspofungin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-01-30T12:48:29Z [Term] id: FYPO:0001884 name: resistance to Calcofluor White def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of Calcofluor White than normal." [PomBase:mah] synonym: "resistance to Calcofluor White during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to Calcofluor White during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to Calcofluor White" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-01-30T12:50:20Z [Term] id: FYPO:0001885 name: decreased protein phosphorylation during salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal when the cell is subject to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during salt stress" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-01-30T12:58:39Z [Term] id: FYPO:0001886 name: meiotic cell cycle entry and sporulation in haploid alt_id: FYPO:0001887 def: "A cellular process phenotype in which haploid cells undergo meiotic nuclear division and attempt to sporulate. Haploid meiosis often results in the formation of a structure that resembles an azygotic ascus. Spores produced from a haploid cell have poor viability and appear to contain only 1/2C DNA on average." [DOI:10.1007/BF00332932, PomBase:mah] synonym: "haploid meiosis" RELATED [PomBase:al] synonym: "haploid sporulation" RELATED [PomBase:al] synonym: "meiosis in haploid" RELATED [PomBase:mah] synonym: "meiotic nuclear division and sporulation in haploid" NARROW [PomBase:mah] synonym: "sporulation in haploid" RELATED [PomBase:mah] synonym: "untimely meiosis" BROAD [PomBase:vw] is_a: FYPO:0009006 ! abnormal meiotic cell cycle entry created_by: midori creation_date: 2013-01-30T13:14:48Z [Term] id: FYPO:0001888 name: substance absent from cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is too low to detect." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2013-01-30T15:19:23Z [Term] id: FYPO:0001889 name: RNA absent from cell def: "A cell phenotype in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] synonym: "transcripts absent from cell" EXACT [PomBase:vw] synonym: "undetectable cellular RNA level" EXACT [PomBase:al] is_a: FYPO:0000826 ! decreased RNA level is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2013-01-30T15:26:28Z [Term] id: FYPO:0001890 name: increased RNA level def: "A cell phenotype in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased cellular mRNA level" NARROW [PomBase:vw] synonym: "increased cellular RNA level" EXACT [PomBase:mah] synonym: "increased RNA accumulation" RELATED [PomBase:mah] synonym: "increased transcript level" EXACT [PomBase:vw] synonym: "RNA accumulation: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000824 ! altered RNA level is_a: FYPO:0000990 ! increased level of substance in cell created_by: midori creation_date: 2013-01-30T15:36:51Z [Term] id: FYPO:0001891 name: increased level of middle meiotic gene mRNA during late meiosis def: "A cell phenotype observed in late meiosis in which the amount of RNA transcribed from middle meiotic genes measured in a cell is higher than normal. Middle meiotic genes are normally transcribed during meiotic nuclear division." [PMID:22558440, PomBase:al, PomBase:mah] synonym: "increased level of middle meiosis gene mRNA during late meiosis" EXACT [PomBase:mah] synonym: "increased level of middle meiotic gene RNA during late meiosis" EXACT [PomBase:mah] synonym: "increased level of middle meiotic gene RNA during late meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased level of middle meiotic gene transcripts during late meiosis" EXACT [PomBase:vw] synonym: "increased RNA level of middle meiotic genes during late meiosis" EXACT [PomBase:al] is_a: FYPO:0005120 ! increased RNA level during meiotic cell cycle created_by: midori creation_date: 2013-01-30T15:43:26Z [Term] id: FYPO:0001892 name: decreased level of middle meiotic gene mRNA during late meiosis def: "A cell phenotype observed in late meiosis in which the amount of RNA transcribed from middle meiotic genes measured in a cell is lower than normal. Middle meiotic genes are normally transcribed during meiotic nuclear division." [PMID:22558440, PomBase:al, PomBase:mah] synonym: "decreased level of middle meiosis gene mRNA during late meiosis" EXACT [PomBase:mah] synonym: "decreased level of middle meiotic gene mRNA during late meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased level of middle meiotic gene transcripts during late meiosis" EXACT [PomBase:vw] synonym: "decreased RNA level of middle meiotic genes during late meiosis" EXACT [PomBase:al] synonym: "reduced level of middle meiotic gene mRNA during late meiosis" EXACT [PomBase:mah] is_a: FYPO:0002959 ! decreased RNA level during meiosis created_by: midori creation_date: 2013-01-30T15:46:28Z [Term] id: FYPO:0001893 name: abnormal sporulation resulting in formation of azygotic ascus with more or fewer than four spores def: "A sporulation phenotype in which azygotic asci that contain more or fewer than four spores form following conjugation, diploid growth, and subsequent azygotic sporulation. Azygotic ascus formation occurs when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:22558440, PomBase:mah] synonym: "abnormal sporulation resulting in formation of azygotic asci with more or fewer than four spores" EXACT [PomBase:mah] synonym: "sporulation defects, azygotic asci with more or fewer than four spores" EXACT [PomBase:mah] is_a: FYPO:0001894 ! abnormal sporulation resulting in formation of ascus with more or fewer than four spores created_by: midori creation_date: 2013-01-30T15:54:57Z [Term] id: FYPO:0001894 name: abnormal sporulation resulting in formation of ascus with more or fewer than four spores def: "A sporulation phenotype in which asci that contain more or fewer than four spores form following conjugation and subsequent sporulation." [PomBase:al, PomBase:mah] synonym: "abnormal ascospore formation resulting in formation of asci with more or fewer than four spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal spore number" EXACT [PomBase:vw] synonym: "abnormal sporulation resulting in formation of asci with more or fewer than four spores" EXACT [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2013-01-30T15:57:25Z [Term] id: FYPO:0001895 name: P-bodies present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic mRNA processing bodies (P-bodies) than normal." [PomBase:mah] synonym: "additional P-bodies present" EXACT [PomBase:mah] synonym: "cytoplasmic mRNA processing bodies present in increased numbers" EXACT [GO:0000932] synonym: "enhanced P-body formation" RELATED [PomBase:al] synonym: "extra P-bodies" EXACT [PomBase:mah] synonym: "increased P-body number" EXACT [PomBase:mah] synonym: "P bodies present in increased numbers" EXACT [GO:0000932] synonym: "P-bodies present in greater numbers" EXACT [PomBase:mah] synonym: "P-bodies present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "P-bodies present in increased numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2013-01-30T16:38:10Z [Term] id: FYPO:0001896 name: enlarged P-bodies def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic mRNA processing bodies (P-bodies) are larger than normal." [PomBase:mah] synonym: "enhanced P-body formation" RELATED [PomBase:al] synonym: "enlarged cytoplasmic mRNA processing bodies" EXACT [GO:0000932] synonym: "enlarged P bodies" EXACT [GO:0000932] synonym: "enlarged P-bodies during mitotic cell cycle" RELATED [PomBase:mah] synonym: "enlarged P-bodies during vegetative growth" EXACT [PomBase:mah] synonym: "enlarged P-body" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2013-01-30T16:40:40Z [Term] id: FYPO:0001897 name: P-bodies present in decreased numbers during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer cytoplasmic mRNA processing bodies (P-bodies) than normal." [PomBase:mah] synonym: "cytoplasmic mRNA processing bodies present in decreased numbers during vegetative growth" EXACT [GO:0000932] synonym: "decreased number of P-bodies present during vegetative growth" RELATED [PomBase:mah] synonym: "decreased P-body formation during vegetative growth" RELATED [PomBase:al] synonym: "decreased P-body number during vegetative growth" EXACT [PomBase:mah] synonym: "fewer P-bodies present during vegetative growth" EXACT [PomBase:mah] synonym: "P bodies present in decreased numbers during vegetative growth" EXACT [GO:0000932] synonym: "P-bodies present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "P-bodies present in reduced numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001898 ! P-bodies present in decreased numbers created_by: midori creation_date: 2013-01-30T16:59:10Z [Term] id: FYPO:0001898 name: P-bodies present in decreased numbers def: "A physical cellular phenotype in which cells contain fewer cytoplasmic mRNA processing bodies (P-bodies) than normal." [PomBase:mah] synonym: "cytoplasmic mRNA processing bodies present in decreased numbers" EXACT [GO:0000932] synonym: "decreased number of P-bodies present" EXACT [PomBase:mah] synonym: "decreased P-body formation" RELATED [PomBase:al] synonym: "decreased P-body number" EXACT [PomBase:mah] synonym: "fewer P-bodies present" EXACT [PomBase:mah] synonym: "P bodies present in decreased numbers" EXACT [GO:0000932] synonym: "P-bodies present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2013-01-30T16:59:23Z [Term] id: FYPO:0001899 name: P-bodies present in decreased numbers during glucose starvation def: "A physical cellular phenotype in which cells contain fewer cytoplasmic mRNA processing bodies (P-bodies) than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "cytoplasmic mRNA processing bodies present in decreased numbers during glucose starvation" EXACT [GO:0000932] synonym: "decreased number of P-bodies present during glucose starvation" EXACT [PomBase:mah] synonym: "decreased P-body formation during glucose starvation" RELATED [PomBase:al] synonym: "decreased P-body number during glucose starvation" EXACT [PomBase:mah] synonym: "fewer P-bodies present during glucose starvation" EXACT [PomBase:mah] synonym: "P bodies present in decreased numbers during glucose starvation" EXACT [GO:0000932] synonym: "P-bodies present in decreased numbers during glucose depletion" EXACT [PomBase:vw] synonym: "P-bodies present in decreased numbers during glucose deprivation" EXACT [PomBase:vw] synonym: "P-bodies present in decreased numbers during glucose limitation" RELATED [PomBase:mah] synonym: "P-bodies present in reduced numbers during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001898 ! P-bodies present in decreased numbers created_by: midori creation_date: 2013-01-30T17:03:35Z [Term] id: FYPO:0001900 name: small P-bodies def: "A physical cellular phenotype in which cytoplasmic mRNA processing bodies (P-bodies) are smaller than normal." [PomBase:mah] synonym: "decreased P-body formation" RELATED [PomBase:al] synonym: "small cytoplasmic mRNA processing bodies" EXACT [GO:0000932] synonym: "small P bodies" EXACT [GO:0000932] synonym: "small P-body" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2013-01-30T17:07:32Z [Term] id: FYPO:0001901 name: small P-bodies during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic mRNA processing bodies (P-bodies) are smaller than normal." [PomBase:mah] synonym: "decreased P-body formation during vegetative growth" RELATED [PomBase:al] synonym: "small cytoplasmic mRNA processing bodies during vegetative growth" EXACT [GO:0000932] synonym: "small P bodies during vegetative growth" EXACT [GO:0000932] synonym: "small P-bodies during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small P-body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001900 ! small P-bodies created_by: midori creation_date: 2013-01-30T17:07:49Z [Term] id: FYPO:0001902 name: small P-bodies during glucose starvation def: "A physical cellular phenotype in which cytoplasmic mRNA processing bodies (P-bodies) are smaller than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased P-body formation during glucose starvation" RELATED [PomBase:al] synonym: "small cytoplasmic mRNA processing bodies during glucose starvation" EXACT [GO:0000932] synonym: "small P bodies during glucose starvation" EXACT [GO:0000932] synonym: "small P-bodies during glucose depletion" EXACT [PomBase:vw] synonym: "small P-bodies during glucose deprivation" EXACT [PomBase:vw] synonym: "small P-bodies during glucose limitation" RELATED [PomBase:mah] synonym: "small P-body during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001900 ! small P-bodies created_by: midori creation_date: 2013-01-30T17:12:02Z [Term] id: FYPO:0001903 name: normal septation index def: "A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type). The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for vegetatively growing wild type cell populations, and less for stationary populations." [PomBase:mah, PomBase:vw] synonym: "normal septation" RELATED [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2013-01-30T17:14:13Z [Term] id: FYPO:0001904 name: premature actomyosin contractile ring disassembly def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the contractile ring collapses or disassembles upon initiation of contraction during anaphase B. Septum formation typically does not occur in cells in which the contractile ring has collapsed." [PMID:22174761, PomBase:mah] synonym: "abnormal contractile ring contraction with contractile ring collapse" EXACT [PomBase:mah] synonym: "actomyosin contractile ring collapse" EXACT [PomBase:mah] synonym: "actomyosin contractile ring collapse upon contraction" EXACT [PomBase:mah] synonym: "actomyosin contractile ring disassembly before septation" EXACT [PomBase:vw] synonym: "advanced actomyosin contractile ring disassembly" EXACT [PomBase:mah] synonym: "cytokinesis defects, collapse of the actinomyosin ring" RELATED [PomBase:mah] synonym: "premature actomyosin contractile ring disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature actomyosin contractile ring disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "premature cytokinetic contractile ring disassembly" EXACT [PomBase:vw] synonym: "premature mitotic contractile ring disassembly" EXACT [PomBase:vw] synonym: "unstable actomyosin contractile ring" RELATED [PomBase:vw] synonym: "unstable actomyosin ring" RELATED [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0004738 ! abnormal actomyosin contractile ring organization created_by: midori creation_date: 2013-01-30T17:33:34Z [Term] id: FYPO:0001905 name: normal mitotic spindle microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number, structure, and orientation of microtubules in the mitotic spindle are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitotic spindle microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "normal spindle microtubules during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth relationship: part_of FYPO:0001399 ! normal mitotic spindle created_by: midori creation_date: 2013-01-30T17:47:11Z [Term] id: FYPO:0001906 name: abnormal cellular response to thiamine starvation def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to thiamine starvation is abnormal." [PomBase:mah] synonym: "abnormal cellular response to thiamin starvation" EXACT [GO:0036225] synonym: "abnormal cellular response to thiamine depletion" EXACT [PomBase:vw] synonym: "abnormal cellular response to thiamine deprivation" EXACT [PomBase:vw] synonym: "abnormal cellular response to thiamine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to thiamine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular response to vitamin B1 starvation" EXACT [GO:0036225] is_a: FYPO:0001339 ! abnormal cellular response to starvation during vegetative growth created_by: midori creation_date: 2013-01-31T14:27:28Z [Term] id: FYPO:0001907 name: growth auxotrophic for thiamine def: "Auxotrophy in which a cell is unable to synthesize thiamine, and therefore requires thiamine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for thiamin" EXACT [GO:0036225, PomBase:mah] synonym: "growth auxotrophic for thiamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for thiamine during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for vitamin B1" EXACT [GO:0036225] synonym: "thiamine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2013-01-31T14:27:37Z [Term] id: FYPO:0001908 name: increased pre-mRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "accumulation of pre-mRNA transcripts" RELATED [PomBase:vw] synonym: "increased pre-mRNA accumulation" RELATED [PomBase:mah] synonym: "increased pre-mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased pre-mRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased pre-mRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-02-06T11:39:09Z [Term] id: FYPO:0001909 name: normal protein glycosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein glycosylation is normal (i.e. indistinguishable from wild type). Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid." [GO:0006486, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein glycosylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide glycosylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2013-01-31T14:53:52Z [Term] id: FYPO:0001910 name: abnormal protein glycosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the glycosylation of one or more specific proteins, or of specific protein sites, is abnormal. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein glycosylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2013-01-31T14:55:43Z [Term] id: FYPO:0001911 name: decreased protein glycosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the glycosylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid." [GO:0006486, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein glycosylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein hypoglycosylation during vegetative growth" EXACT [PomBase:vw] synonym: "reduced protein glycosylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001910 ! abnormal protein glycosylation during vegetative growth created_by: midori creation_date: 2013-01-31T14:55:50Z [Term] id: FYPO:0001912 name: abnormal ubiquitin ligase activity def: "A molecular function phenotype in which the observed rate of ubiquitin ligase activity is abnormal." [PomBase:mah] synonym: "abnormal ubiquitin-protein ligase activity" EXACT [GO:0004842] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-01-31T15:09:44Z [Term] id: FYPO:0001913 name: abolished ubiquitin ligase activity def: "A molecular function phenotype in which ubiquitin ligase activity is absent." [PomBase:mah] synonym: "abolished ubiquitin-protein ligase activity" EXACT [GO:0004842] synonym: "ubiquitin ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001912 ! abnormal ubiquitin ligase activity created_by: midori creation_date: 2013-01-31T15:09:55Z [Term] id: FYPO:0001914 name: abnormal prospore membrane formation def: "A cellular process phenotype in which prospore membrane formation is abnormal. In prospore membrane formation, the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed." [GO:0032120, PomBase:mah] synonym: "abnormal ascospore-type prospore membrane assembly" EXACT [GO:0032120] synonym: "abnormal enclosure of nucleus by forespore membrane" RELATED [PomBase:vw] synonym: "abnormal engulfment of nucleus by forespore membrane" RELATED [PomBase:vw] synonym: "abnormal forespore membrane formation" EXACT [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0001013 ! abnormal membrane organization is_a: FYPO:0002739 ! abnormal meiotic cell cycle process relationship: part_of FYPO:0000196 ! abnormal prospore formation created_by: midori creation_date: 2013-01-31T15:42:32Z [Term] id: FYPO:0001915 name: abolished prospore membrane formation def: "A cellular process phenotype in which prospore membrane formation does not occur." [PomBase:mah] synonym: "abolished ascospore-type prospore membrane assembly" EXACT [GO:0032120] synonym: "abolished forespore membrane formation" EXACT [GO:0032120] synonym: "prospore membrane formation abolished" EXACT [PomBase:mah] is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2013-01-31T15:47:54Z [Term] id: FYPO:0001916 name: elongated mononucleate vegetative cell def: "A cell phenotype in which a cell contains one nucleus, is longer than normal, and has a greater length:diameter ratio than normal." [PomBase:mah] synonym: "elongated mononucleate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "long mononucleate cell" EXACT [PomBase:vw] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000060 ! mononucleate vegetative cell relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2013-02-06T11:57:40Z [Term] id: FYPO:0001917 name: inviable elongated mononucleate monoseptate vegetative cell def: "A cell phenotype in which a cell is inviable, contains a single septum, has one nucleus in the septated cell, and is elongated." [PomBase:mah] synonym: "inviable elongated mononucleate monoseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable long monoseptate mononucleate cell" EXACT [PomBase:vw] synonym: "lethal; elongated mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002303 ! inviable mononucleate monoseptate vegetative cell with anucleate compartment is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology is_a: FYPO:0004255 ! inviable elongated mononucleate vegetative cell is_a: FYPO:0004979 ! elongated monoseptate vegetative cell created_by: midori creation_date: 2013-02-06T12:00:33Z [Term] id: FYPO:0001918 name: normal growth on trifluoperazine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trifluoperazine." [PomBase:mah] synonym: "normal cell population growth in presence of trifluoperazine" EXACT [PomBase:mah] synonym: "normal cell population growth on trifluoperazine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to trifluoperazine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on trifluoperazine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-02-06T12:08:16Z [Term] id: FYPO:0001919 name: fragmented nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is broken into multiple small fragments that are smaller than a normal nucleus." [PomBase:mah] synonym: "fragmented nuclear DNA during vegetative growth" RELATED [PomBase:mah] synonym: "fragmented nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "loss of nuclear integrity during vegetative growth" RELATED [PomBase:al] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth is_a: FYPO:0006661 ! fragmented nucleus created_by: midori creation_date: 2013-02-06T14:32:47Z [Term] id: FYPO:0001920 name: decreased protein export from nucleus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein export from nucleus is decreased. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein export from nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein export from nucleus" EXACT [PomBase:mah] is_a: FYPO:0000345 ! abnormal protein export from nucleus during vegetative growth is_a: FYPO:0000508 ! decreased nuclear export created_by: midori creation_date: 2013-02-06T14:35:44Z [Term] id: FYPO:0001921 name: abolished protein export from nucleus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein export from the nucleus does not occur. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent protein export from nucleus" EXACT [PomBase:mah] synonym: "protein export from nucleus abolished" EXACT [PomBase:mah] synonym: "protein export from nucleus abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000345 ! abnormal protein export from nucleus during vegetative growth is_a: FYPO:0000507 ! abolished nuclear export created_by: midori creation_date: 2013-02-06T14:37:54Z [Term] id: FYPO:0001922 name: normal protein dephosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein dephosphorylation is normal (i.e. indistinguishable from wild type). Protein dephosphorylation is the removal of a phosphate group from a protein amino acid." [GO:0006470, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein dephosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide dephosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2013-02-06T14:58:05Z [Term] id: FYPO:0001923 name: normal protein dephosphorylation during mitotic G2/M transition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein dephosphorylation is normal (i.e. indistinguishable from wild type) during the G2/M phase transition of the mitotic cell cycle. Protein dephosphorylation is the removal of a phosphate group from a protein amino acid." [GO:0006470, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein dephosphorylation during G2/M phase transition" EXACT [PomBase:al] synonym: "normal protein dephosphorylation during G2/M transition during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein dephosphorylation during G2/M transition of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein/peptide dephosphorylation during mitotic G2/M transition" EXACT [PomBase:mah] is_a: FYPO:0001922 ! normal protein dephosphorylation during vegetative growth created_by: midori creation_date: 2013-02-06T15:00:26Z [Term] id: FYPO:0001924 name: inviable after spore germination, without cell division, cell cycle arrest def: "A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest, and eventually dies without completing cell division." [PomBase:mah] synonym: "inviable following spore germination, without cell division, cell cycle arrest" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, cell cycle arrest" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression is_a: FYPO:0001991 ! inviable after spore germination, without cell division relationship: has_part FYPO:0000502 ! abnormally arrested mitotic cell cycle progression created_by: midori creation_date: 2013-02-06T15:14:31Z [Term] id: FYPO:0001925 name: normal cellular response to gamma radiation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to gamma radiation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to gamma radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to gamma radiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal sensitivity to gamma radiation" EXACT [PomBase:vw] is_a: FYPO:0000968 ! normal cellular response to stress during vegetative growth created_by: midori creation_date: 2013-02-06T15:19:50Z [Term] id: FYPO:0001926 name: normal cellular response to hydroxyurea def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to hydroxyurea is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note: Use this term only if a specific response, such as cell cycle delay, is measured. If only cell growth in the presence of hydroxyurea is assayed, use 'normal cell population growth on hydroxyurea' (FYPO:000063). synonym: "normal cellular response to HU" EXACT [PomBase:mah] synonym: "normal cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2013-02-06T15:26:30Z [Term] id: FYPO:0001927 name: normal cell cycle regulation during cellular response to ionizing radiation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation." [PomBase:mah] synonym: "normal cell cycle delay following ionizing radiation" EXACT [PomBase:al] synonym: "normal cell cycle regulation during cellular response to gamma radiation" NARROW [PomBase:al, PomBase:mah] synonym: "normal cell cycle regulation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell cycle regulation in response to ionizing radiation" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2013-02-06T15:30:14Z [Term] id: FYPO:0001928 name: normal regulation of mitotic cell cycle def: "A regulation phenotype in which regulation of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell cycle regulation during vegetative growth" EXACT [PomBase:mah] synonym: "normal regulation of mitotic cell cycle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000411 ! normal mitotic cell cycle is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2013-02-06T15:31:52Z [Term] id: FYPO:0001929 name: normal cell cycle regulation during cellular response to hydroxyurea def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to hydroxyurea is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to hydroxyurea." [PomBase:mah] synonym: "normal cell cycle arrest in response to HU" NARROW [PMID:1706223, PomBase:al] synonym: "normal cell cycle delay following hydroxyurea exposure" NARROW [PomBase:al] synonym: "normal cell cycle regulation during cellular response to HU" EXACT [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell cycle regulation in response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001926 ! normal cellular response to hydroxyurea is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2013-02-06T15:43:31Z [Term] id: FYPO:0001930 name: abnormal cellular response to gamma radiation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to gamma radiation is abnormal." [PomBase:mah] synonym: "abnormal cellular response to gamma radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to gamma radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sensitivity to gamma radiation" EXACT [PomBase:vw] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2013-02-06T15:55:54Z [Term] id: FYPO:0001931 name: abnormal mitotic cell cycle regulation during cellular response to gamma radiation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to gamma radiation is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to gamma radiation. The most common abnormality is for the cell cycle to progress as in the absence of gamma radiation." [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following gamma radiation" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to gamma radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to gamma radiation" EXACT [PomBase:mah] is_a: FYPO:0001930 ! abnormal cellular response to gamma radiation is_a: FYPO:0003489 ! abnormal mitotic cell cycle regulation during cellular response to ionizing radiation created_by: midori creation_date: 2013-02-06T15:56:28Z [Term] id: FYPO:0001932 name: abnormal cellular response to hydroxyurea def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to hydroxyurea is abnormal." [PomBase:mah] comment: Note: Use this term only if a specific response, such as cell cycle delay, is measured. If only cell growth in the presence of hydroxyurea is assayed, use 'sensitive to hydroxyurea' (FYPO:0000088) if applicable. synonym: "abnormal cellular response to HU" EXACT [GO:0071280] synonym: "abnormal cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype created_by: midori creation_date: 2013-02-06T16:01:04Z [Term] id: FYPO:0001933 name: abnormal mitotic cell cycle regulation during cellular response to hydroxyurea def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to hydroxyurea is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to hydroxyurea. The most common abnormality is for the cell cycle to progress as in the absence of hydroxyurea." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to hydroxyurea during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following hydroxyurea exposure" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to HU" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001932 ! abnormal cellular response to hydroxyurea created_by: midori creation_date: 2013-02-06T16:01:24Z [Term] id: FYPO:0001934 name: abolished cell population growth on glycerol carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing glycerol as the carbon source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with glycerol as the carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished glycerol utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished growth on glycerol carbon source" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth on glycerol carbon source" EXACT [PomBase:mah] synonym: "cell population growth on glycerol carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0000684 ! decreased cell population growth on glycerol carbon source is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2013-02-06T16:08:06Z [Term] id: FYPO:0001935 name: abnormal proton-transporting ATP synthase activity, rotational mechanism def: "A molecular function phenotype in which the observed rate of proton-transporting ATP synthase activity by a rotational mechanism is abnormal." [PomBase:mah] synonym: "abnormal hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [PomBase:mah] synonym: "abnormal mitochondrial proton-transporting ATP synthase activity" NARROW [PomBase:vw] synonym: "abnormal proton-transporting ATP synthase activity" RELATED [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-06T16:22:30Z [Term] id: FYPO:0001936 name: decreased proton-transporting ATP synthase activity, rotational mechanism def: "A molecular function phenotype in which the observed rate of proton-transporting ATP synthase activity by a rotational mechanism is decreased." [PomBase:mah] synonym: "decreased hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [PomBase:mah] synonym: "decreased mitochondrial proton-transporting ATP synthase activity" NARROW [PomBase:vw] synonym: "decreased proton-transporting ATP synthase activity" RELATED [PomBase:mah] synonym: "reduced mitochondrial proton-transporting ATP synthase activity" NARROW [PomBase:vw] synonym: "reduced proton-transporting ATP synthase activity, rotational mechanism" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001935 ! abnormal proton-transporting ATP synthase activity, rotational mechanism created_by: midori creation_date: 2013-02-06T16:22:37Z [Term] id: FYPO:0001937 name: abnormal cytochrome-c oxidase activity def: "A molecular function phenotype in which the observed rate of cytochrome-c oxidase activity is abnormal." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'abnormal cellular respiration' (FYPO:0000078). is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-06T16:26:21Z [Term] id: FYPO:0001938 name: decreased cytochrome-c oxidase activity def: "A molecular function phenotype in which the observed rate of cytochrome-c oxidase activity is decreased." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'decreased cellular respiration' (FYPO:0000342). synonym: "reduced cytochrome-c oxidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001937 ! abnormal cytochrome-c oxidase activity created_by: midori creation_date: 2013-02-06T16:26:27Z [Term] id: FYPO:0001939 name: abnormal ubiquinol-cytochrome-c reductase activity def: "A molecular function phenotype in which the observed rate of ubiquinol-cytochrome-c reductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-06T16:37:49Z [Term] id: FYPO:0001940 name: decreased ubiquinol-cytochrome-c reductase activity def: "A molecular function phenotype in which the observed rate of ubiquinol-cytochrome-c reductase activity is decreased." [PomBase:mah] synonym: "reduced ubiquinol-cytochrome-c reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001939 ! abnormal ubiquinol-cytochrome-c reductase activity created_by: midori creation_date: 2013-02-06T16:37:57Z [Term] id: FYPO:0001941 name: resistance to cerulenin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cerulenin than normal." [PomBase:mah] synonym: "resistance to cerulenin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cerulenin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to cerulenin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-02-06T16:51:46Z [Term] id: FYPO:0001942 name: increased duration of lag phase def: "A cell population phenotype in which a population in a culture remains in lag phase longer than normal. The onset of exponential growth is thus delayed." [PomBase:mah] synonym: "delayed exponential growth" EXACT [PomBase:al] synonym: "prolonged lag phase" EXACT [PomBase:al] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2013-02-06T16:55:57Z [Term] id: FYPO:0001943 name: abnormal microtubule binding def: "A molecular function phenotype in which occurrence of microtubule binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with microtubules that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-02-06T17:06:58Z [Term] id: FYPO:0001944 name: abolished microtubule binding def: "A molecular function phenotype in which microtubule binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with microtubules that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "microtubule binding abolished" EXACT [PomBase:mah] is_a: FYPO:0001943 ! abnormal microtubule binding created_by: midori creation_date: 2013-02-06T17:07:06Z [Term] id: FYPO:0001945 name: normal protein secretion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein secretion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein secretion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2013-02-06T17:11:58Z [Term] id: FYPO:0001946 name: abolished mitotic sister chromatid separation def: "A cellular process phenotype in which mitotic sister chromatid separation does not occur." [PomBase:mah] synonym: "abolished mitotic chromosome separation" EXACT [PomBase:mah] synonym: "absent mitotic sister chromatid separation" EXACT [PomBase:mah] synonym: "mitotic sister chromatid separation abolished" EXACT [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2013-02-07T11:58:07Z [Term] id: FYPO:0001947 name: obsolete abnormal cell cycle arrest in mitotic anaphase, with unseparated sister chromatids def: "OBSOLETE. A cellular process phenotype in which progression through the mitotic cell cycle is arrested in anaphase under conditions where arrest does not normally occur, and sister chromatids have not separated. The unseparated chromosomes remain condensed." [PomBase:mah] comment: This term was made obsolete because a cell with unseparated sister chromatids is by definition in metaphase. synonym: "abnormal cell cycle arrest in mitotic anaphase, with unseparated sister chromatids, during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic anaphase, with unseparated, condensed chromosomes" EXACT [PomBase:mah, PomBase:vw] synonym: "abnormal cell cycle arrest in mitotic anaphase, with unseparated, condensed sister chromatids" EXACT [PomBase:mah, PomBase:vw] synonym: "abnormal mitotic cell cycle arrest in anaphase, with unseparated sister chromatids" EXACT [PomBase:mah] synonym: "absence of chromosome separation, abnormal mitotic anaphase arrest with condensed chromosomes" EXACT [PomBase:vw] is_obsolete: true consider: FYPO:0000620 created_by: midori creation_date: 2013-02-07T12:21:22Z [Term] id: FYPO:0001948 name: increased level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is higher than normal." [PomBase:mah] synonym: "increased cytosolic level of substance" EXACT [PomBase:mah] synonym: "increased level of substance in cytosol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001604 ! altered level of substance in cytosol created_by: midori creation_date: 2013-02-07T12:53:32Z [Term] id: FYPO:0001949 name: increased cytosolic calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in the cytosol is higher than normal." [PomBase:mah] synonym: "increased cytosolic calcium ion level" EXACT [PomBase:mah] synonym: "increased cytosolic calcium ion level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cytosolic calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of calcium ions in cytosol" EXACT [PomBase:mah] synonym: "increased levels of free cytosolic calcium" EXACT [PomBase:vw] is_a: FYPO:0001198 ! increased cellular calcium level is_a: FYPO:0001948 ! increased level of substance in cytosol created_by: midori creation_date: 2013-02-07T12:54:36Z [Term] id: FYPO:0001950 name: decreased sequestered calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion determined to be sequestered in a cell is lower than normal." [PMID:2145281, PomBase:mah] synonym: "decreased cellular sequestered calcium level" EXACT [PomBase:mah] synonym: "decreased levels of sequestered calcium" EXACT [PomBase:vw] synonym: "decreased sequestered calcium ion level" EXACT [PomBase:mah] synonym: "decreased sequestered calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased sequestered calcium level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced sequestered calcium level" EXACT [PomBase:mah] is_a: FYPO:0001197 ! decreased cellular calcium level created_by: midori creation_date: 2013-02-07T12:57:28Z [Term] id: FYPO:0001951 name: abnormal calcium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of calcium ions out of a cell is abnormal." [PomBase:mah] synonym: "abnormal calcium efflux from cell" EXACT [PomBase:vw] synonym: "abnormal calcium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal calcium export during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal calcium export from cell" NARROW [PomBase:mah] synonym: "abnormal calcium ion export" EXACT [PomBase:mah] synonym: "abnormal calcium ion export from cell" EXACT [PomBase:mah] synonym: "abnormal cellular calcium export" EXACT [PomBase:al] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2013-02-07T13:03:00Z [Term] id: FYPO:0001952 name: decreased calcium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of calcium ions out of a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased calcium efflux from cell" EXACT [PomBase:vw] synonym: "decreased calcium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased calcium export during vegetative growth" EXACT [PomBase:mah] synonym: "decreased calcium export from cell" NARROW [PomBase:mah] synonym: "decreased calcium ion export" EXACT [PomBase:mah] synonym: "decreased cellular calcium export" EXACT [PomBase:al] synonym: "reduced calcium export" EXACT [PomBase:mah] is_a: FYPO:0001951 ! abnormal calcium export created_by: midori creation_date: 2013-02-07T13:03:07Z [Term] id: FYPO:0001953 name: abnormal calcium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal calcium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal calcium import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal calcium import into cell" EXACT [PomBase:mah] synonym: "abnormal calcium ion import" EXACT [PomBase:mah] synonym: "abnormal calcium ion import across plasma membrane" EXACT [GO:0098703] synonym: "abnormal cellular calcium import" EXACT [PomBase:al] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2013-02-07T13:10:35Z [Term] id: FYPO:0001954 name: decreased calcium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased calcium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased calcium import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased calcium import into cell" EXACT [PomBase:mah] synonym: "decreased calcium ion import" EXACT [PomBase:mah] synonym: "decreased calcium ion import across plasma membrane" EXACT [GO:0098703] synonym: "decreased calcium uptake" EXACT [PomBase:mah] synonym: "decreased calcium uptake into intracellular compartments" RELATED [PMID:2145281, PomBase:vw] synonym: "decreased cellular calcium import" EXACT [PomBase:al] synonym: "reduced calcium import" EXACT [PomBase:mah] is_a: FYPO:0001953 ! abnormal calcium import created_by: midori creation_date: 2013-02-07T13:12:30Z [Term] id: FYPO:0001955 name: spheroid cell def: "A cell morphology phenotype in which a cell is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] synonym: "cell morphology, round cells" RELATED [PomBase:mah] synonym: "cell morphology, rounded cells" RELATED [PomBase:mah] synonym: "rounded cell" EXACT [PomBase:vw] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2013-02-07T13:58:40Z [Term] id: FYPO:0001956 name: spherical cell def: "A cell morphology phenotype in which a cell is formed in the shape of a sphere." [PomBase:mah] synonym: "orb" EXACT [PomBase:jh, PomBase:vw] is_a: FYPO:0001955 ! spheroid cell created_by: midori creation_date: 2013-02-07T13:58:48Z [Term] id: FYPO:0001959 name: normal cAMP level during nitrogen starvation def: "A cell phenotype in which the amount of cyclic AMP measured in a cell during nitrogen starvation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "normal cAMP accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "normal cAMP level during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal cAMP level during nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal cellular cAMP level during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal cyclic AMP level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001666 ! normal cAMP level created_by: midori creation_date: 2013-02-07T14:28:06Z [Term] id: FYPO:0001960 name: abnormal DNA topoisomerase II activity def: "A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is abnormal." [PomBase:mah] synonym: "abnormal DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity" EXACT [GO:0003918] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-07T14:33:51Z [Term] id: FYPO:0001961 name: decreased DNA topoisomerase II activity def: "A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is decreased." [PomBase:mah] synonym: "decreased DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity" EXACT [GO:0003918] synonym: "reduced DNA topoisomerase II activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001960 ! abnormal DNA topoisomerase II activity created_by: midori creation_date: 2013-02-07T14:34:15Z [Term] id: FYPO:0001962 name: abolished protein phosphatase activity def: "A molecular function phenotype in which a protein phosphatase activity is absent." [PomBase:mah] synonym: "protein phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0001756 ! abnormal protein phosphatase activity created_by: midori creation_date: 2013-02-07T14:36:28Z [Term] id: FYPO:0001963 name: resistance to papulacandin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of papulacandin B than normal." [PomBase:mah] synonym: "resistance to papulacandin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to papulacandin B during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to papulacandin B" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-02-07T14:39:04Z [Term] id: FYPO:0001964 name: resistance to aculeacin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aculeacin A than normal." [PomBase:mah] synonym: "resistance to aculeacin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to aculeacin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to aculeacin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-02-07T14:40:07Z [Term] id: FYPO:0001965 name: resistance to papulacandin D def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of papulacandin D than normal." [PomBase:mah] synonym: "resistance to papulacandin D during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to papulacandin D during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to papulacandin D" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-02-07T14:40:48Z [Term] id: FYPO:0001966 name: sensitive to aculeacin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to aculeacin A. Cells stop growing (and may die) at a concentration of aculeacin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to aculeacin A" EXACT [PomBase:mah] synonym: "sensitive to aculeacin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to aculeacin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-02-07T14:51:06Z [Term] id: FYPO:0001967 name: abnormal 1,3-beta-D-glucan synthase activity def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-07T14:57:37Z [Term] id: FYPO:0001968 name: increased 1,3-beta-D-glucan synthase activity def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001967 ! abnormal 1,3-beta-D-glucan synthase activity created_by: midori creation_date: 2013-02-07T14:57:45Z [Term] id: FYPO:0001969 name: increased 1,3-beta-D-glucan synthase activity during growth on papulacandin B def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is increased when cells are grown in medium containing papulacandin B." [PomBase:mah] is_a: FYPO:0001968 ! increased 1,3-beta-D-glucan synthase activity created_by: midori creation_date: 2013-02-07T14:57:51Z [Term] id: FYPO:0001970 name: increased 1,3-beta-D-glucan synthase activity during growth on aculeacin A def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is increased when cells are grown in medium containing aculeacin A." [PomBase:mah] is_a: FYPO:0001968 ! increased 1,3-beta-D-glucan synthase activity created_by: midori creation_date: 2013-02-07T15:01:22Z [Term] id: FYPO:0001971 name: abnormal cell separation after cytokinesis resulting in chained cells def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormal, and results in the formation of a chain of cells. Cells in the chain visually resemble wild-type cells, except that they remain connected, often via remnants of septum edging material, and may continue to undergo normal mitosis and septum formation." [PMID:8873452, PomBase:mah, PomBase:vw] comment: This phenotype usually results from a defect late in septum degradation. synonym: "abnormal cell separation after cytokinesis resulting in chained cells during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell separation after cytokinesis resulting in chained cells during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cytokinetic cell separation resulting in chained cells" EXACT [GO:0000920] synonym: "cell clumping" RELATED [PomBase:vw] synonym: "clumped cells" RELATED [PomBase:vw] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: midori creation_date: 2013-02-07T15:15:49Z [Term] id: FYPO:0001972 name: abnormal cell separation after cytokinesis resulting in septated cell def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormal, and results in the formation of a septated cell. Nuclear division, contractile ring formation and constriction, and septum assembly are apparently normal, but the septum does not degrade. Additional rounds of nuclear division and cytokinesis may take place, resulting in the formation of a multiseptate cell." [PMID:12654901, PomBase:mah, PomBase:vw] comment: This phenotype usually results from a defect late in septum degradation. synonym: "abnormal cell separation after cytokinesis resulting in septated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell separation after cytokinesis resulting in septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cytokinetic cell separation resulting in septated cell" EXACT [GO:0000920] synonym: "abnormal septum digestion after cytokinesis resulting in septated cell" EXACT [GO:0000920] synonym: "boomerang shaped" RELATED [PomBase:vw] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: midori creation_date: 2013-02-07T15:23:02Z [Term] id: FYPO:0001973 name: obsolete abnormal cell separation after cytokinesis, with abnormal nuclear division def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear division, cytokinesis and subsequent cell separation are abnormal, resulting in the formation of a cell in which an undivided mass of DNA is located on one side of the septum. The septum does not degrade." [PMID:3283148, PomBase:mah, PomBase:vw] comment: This term was made obsolete because no cells are known to match the criteria of its definition (cut plus abnormal septum disassembly after cytokinesis). Its name was also not updated to reflect the name of the referenced GO term. synonym: "abnormal cell separation after cytokinesis, with abnormal nuclear division during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell separation after cytokinesis, with abnormal nuclear division during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cytokinetic cell separation, with abnormal nuclear division" EXACT [GO:0000920] is_obsolete: true consider: FYPO:0000229 created_by: midori creation_date: 2013-02-07T15:28:25Z [Term] id: FYPO:0001974 name: increased number of cells with 1C DNA content def: "A cell population phenotype in which a greater than normal number of cells contain 1C DNA content. This may result from cell cycle arrest or delay." [PomBase:al] synonym: "increased amount of cells with 1C DNA content" EXACT [PomBase:al] synonym: "increased number of cells containing 1C DNA" EXACT [PomBase:al] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2013-02-07T16:00:02Z [Term] id: FYPO:0001975 name: normal growth on nocodazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nocodazole." [PomBase:mah] synonym: "normal cell population growth in presence of nocodazole" EXACT [PomBase:mah] synonym: "normal cell population growth on nocodazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to nocodazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on nocodazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-02-07T16:04:27Z [Term] id: FYPO:0001976 name: normal cytoplasmic microtubules during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cytoplasmic microtubule morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule structure during vegetative growth" NARROW [PomBase:mah] synonym: "normal cytoplasmic microtubules during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth is_a: FYPO:0007809 ! normal cytoplasmic microtubules created_by: midori creation_date: 2013-02-07T16:06:45Z [Term] id: FYPO:0001977 name: increased cell wall galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is greater than normal." [PomBase:mah] synonym: "increased cell wall galactomannan accumulation" RELATED [PomBase:mah] synonym: "increased cell wall galactomannan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell wall galactomannan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2013-02-07T16:08:34Z [Term] id: FYPO:0001978 name: bent mitotic spindle def: "A spindle phenotype in which the mitotic spindle is not straight, but instead forms an angle where microtubules from opposite poles interdigitate." [PMID:1538784, PMID:2145514, PomBase:mah] synonym: "bent bipolar mitotic spindle" EXACT [PomBase:vw] synonym: "bent mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "bent spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "V-shaped bipolar mitotic spindle" EXACT [PomBase:vw] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2013-02-08T17:13:24Z [Term] id: FYPO:0001979 name: increased lariat intron level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which excised introns in lariat form (i.e. not linearized) are present at greater levels than normal." [PomBase:al, PomBase:mah] synonym: "accumulation of lariat introns" RELATED [PomBase:mah] synonym: "increased lariat intron level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased lariat intron level during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of lariat introns" EXACT [PomBase:vw] synonym: "lariat intron accumulation" RELATED [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-02-13T14:38:24Z [Term] id: FYPO:0001980 name: normal RNA processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is normal (i.e. indistinguishable from wild type). RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." [GO:0006396, PomBase:mah] synonym: "normal RNA processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000859 ! normal metabolic process during vegetative growth created_by: midori creation_date: 2013-02-13T14:50:30Z [Term] id: FYPO:0001981 name: decreased rate of DNA replication def: "A cellular process phenotype in which the rate, or speed, of DNA replication is decreased." [PomBase:mah] synonym: "reduced rate of DNA replication" EXACT [PomBase:mah] is_a: FYPO:0000217 ! abnormal DNA replication created_by: midori creation_date: 2013-02-13T14:54:35Z [Term] id: FYPO:0001982 name: decreased rate of DNA replication during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA replication is decreased." [PomBase:mah] synonym: "decreased rate of DNA replication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced rate of DNA replication during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication is_a: FYPO:0001981 ! decreased rate of DNA replication created_by: midori creation_date: 2013-02-13T14:54:57Z [Term] id: FYPO:0001983 name: protein absent from cell def: "A cell phenotype in which the amount of protein measured in a cell is too low to detect. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "undetectable cellular protein level" EXACT [PomBase:al] is_a: FYPO:0000835 ! decreased protein level is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2013-02-13T15:06:40Z [Term] id: FYPO:0001984 name: protein absent from cell during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "undetectable cellular protein level during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0001983 ! protein absent from cell created_by: midori creation_date: 2013-02-13T15:07:15Z [Term] id: FYPO:0001985 name: abnormal phenotype def: "A phenotype that shows detectable differences from normal. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast abnormal phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype relationship: inheres_in FYPO:0000001 ! phenotype created_by: midori creation_date: 2013-02-13T15:39:55Z [Term] id: FYPO:0001986 name: resistance to 5-fluorouracil def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-fluorouracil than normal." [PomBase:mah] synonym: "resistance to 5-fluorouracil during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to 5-fluorouracil during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to 5-FU" EXACT [PomBase:al] synonym: "resistant to 5-fluorouracil" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-02-13T16:51:16Z [Term] id: FYPO:0001987 name: sensitive to high pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pH higher than that of standard S. pombe growth media (about 5.8). Cells stop growing (and may die) at a pH that allows wild type cells to grow." [PomBase:mah] comment: Also see 'sensitive to alkalinity' (FYPO:0000723). synonym: "decreased growth during cellular response to high pH" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to high pH" EXACT [PomBase:mah] synonym: "hypersensitive to high pH" EXACT [PomBase:mah] synonym: "sensitive to high pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to high pH during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2013-02-13T17:07:12Z [Term] id: FYPO:0001988 name: normal cell population growth at high pH def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a pH higher than that of standard S. pombe growth medium (abut 5.8)." [PomBase:mah] synonym: "normal growth at high pH" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth at high pH" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-02-13T17:11:42Z [Term] id: FYPO:0001989 name: sensitive to low pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pH lower than that of standard S. pombe growth media (about 5.8). Cells stop growing (and may die) at a pH that allows wild type cells to grow." [PomBase:mah] comment: Also see 'sensitive to acidity' (FYPO:0000722). synonym: "decreased growth during cellular response to low pH" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to low pH" EXACT [PomBase:mah] synonym: "hypersensitive to low pH" EXACT [PomBase:mah] synonym: "sensitive to low pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to low pH during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2013-02-13T17:18:14Z [Term] id: FYPO:0001990 name: normal cell population growth at low pH def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a pH lower than that of standard S. pombe growth medium (abut 5.8)." [PomBase:mah] synonym: "normal growth at low pH" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth at low pH" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-02-13T17:20:01Z [Term] id: FYPO:0001991 name: inviable after spore germination, without cell division def: "A phenotype in which a spore germinates to produce a cell that dies without completing cell division." [PomBase:al, PomBase:mah] synonym: "inviable after spore germination, no cell division" EXACT [PomBase:al] synonym: "inviable following spore germination, without cell division" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division" EXACT [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2013-02-13T17:25:34Z [Term] id: FYPO:0001992 name: inviable elongated mononucleate vegetative cell with mislocalized septum alt_id: FYPO:0001993 def: "A cell phenotype in which a cell contains a single septum, has one nucleus, is elongated, and is inviable. The septum is in an abnormal location, and the nucleus is located in one compartment of the septated cell." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155), 'septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation' (FYPO:0003166), or their descendants, because these phenotypes often co-occur. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable elongated mononucleate cell with abnormal septum location" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with abnormal septum position" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with asymmetric septum" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with asymmetrically located septum" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with mislocalised septum" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with mislocalized septum during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate monoseptate vegetative cell with mislocalized septum" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate vegetative cell with mislocalized septum and mislocalized nucleus" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate vegetative cell with mislocalized septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate vegetative cell with misplaced septum" EXACT [PomBase:vw] synonym: "inviable elongated mononucleate vegetative cell with single mislocalized septum" EXACT [PomBase:mah] synonym: "inviable long mononucleate cell with mislocalized septum" EXACT [PomBase:vw] synonym: "inviable vegetative elongated mononucleate cell with mislocalized septum" EXACT [PomBase:mah] synonym: "lethal; elongated mononucleate vegetative cell with mislocalized septum" EXACT [PomBase:mah] is_a: FYPO:0001226 ! inviable mononucleate vegetative cell with mislocalized septum and anucleate compartment is_a: FYPO:0001917 ! inviable elongated mononucleate monoseptate vegetative cell is_a: FYPO:0002889 ! inviable elongated vegetative cell with abnormal septum relationship: output_of FYPO:0000229 ! cut created_by: midori creation_date: 2013-02-20T16:55:53Z [Term] id: FYPO:0001994 name: inviable swollen elongated mononucleate vegetative cell with mislocalized septum near new end def: "A cell phenotype in which a cell contains a single septum, has one nucleus, is swollen, is elongated, and is inviable. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. The septum is in an abnormal location, and the nucleus is located in one compartment of the septated cell. The cell compartment containing the nucleus is swollen (i.e. has a larger diameter than the other compartment)." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable elongated mononucleate vegetative cell with mislocalized septum near new end and increased cell volume" EXACT [PomBase:mah] synonym: "inviable enlarged elongated mononucleate vegetative cell with mislocalized septum near new end" EXACT [PomBase:mah] synonym: "inviable swollen elongated mononucleate cell with mislocalized septum near non-growing end" NARROW [PomBase:mah] synonym: "inviable swollen elongated mononucleate monoseptate vegetative cell with mislocalized septum near new end" EXACT [PomBase:mah] synonym: "inviable swollen elongated mononucleate vegetative cell with mislocalised septum near new end" EXACT [PomBase:mah] synonym: "inviable swollen elongated mononucleate vegetative cell with mislocalized septum near new end and mislocalized nucleus" EXACT [PomBase:mah] synonym: "inviable swollen elongated mononucleate vegetative cell with mislocalized septum near new end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable swollen elongated mononucleate vegetative cell with misplaced septum near new end" EXACT [PomBase:vw] synonym: "inviable swollen elongated mononucleate vegetative cell with single mislocalized septum near new end" EXACT [PomBase:mah] synonym: "lethal; swollen elongated mononucleate vegetative cell with mislocalized septum near new end" EXACT [PomBase:mah] synonym: "long swollen mononucleate cell with mislocalized septum near new end" EXACT [PomBase:vw] synonym: "long swollen mononucleate cell with mislocalized septum near non-growing end" NARROW [PomBase:vw] synonym: "swollen elongated mononucleate cell with abnormal septum location near new end" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with abnormal septum location near non-growing end" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with abnormal septum position near new end" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with abnormal septum position near non-growing end" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with asymmetric septum near new end" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with asymmetric septum near non-growing end" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with asymmetrically located septum near new end" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with asymmetrically located septum near non-growing end" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with mislocalised septum near new end" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with mislocalised septum near non-growing end" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with mislocalized septum near new end" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with mislocalized septum near new end during vegetative growth" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with mislocalized septum near non-growing end" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with mislocalized septum near non-growing end during vegetative growth" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate vegetative cell with mislocalized septum near non-growing end" NARROW [PomBase:mah] is_a: FYPO:0001992 ! inviable elongated mononucleate vegetative cell with mislocalized septum is_a: FYPO:0002103 ! inviable swollen mononucleate monoseptate vegetative cell is_a: FYPO:0002845 ! inviable swollen elongated septated vegetative cell relationship: has_part FYPO:0001391 ! mislocalized septum, near new end relationship: output_of FYPO:0002017 ! abnormal cell cycle arrest in mitotic interphase before NETO created_by: midori creation_date: 2013-02-20T17:01:11Z [Term] id: FYPO:0001995 name: normal growth on polymyxin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing polymyxin B." [PomBase:mah] synonym: "normal cell population growth in presence of polymyxin B" EXACT [PomBase:mah] synonym: "normal cell population growth on polymyxin B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to polymyxin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on polymixin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-02-25T16:25:59Z [Term] id: FYPO:0001996 name: RNA absent from cell during nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell is too low to detect when the cell is subject to nitrogen starvation. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "RNA absent from cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "RNA absent from cell during nitrogen deprivation" EXACT [PomBase:vw] synonym: "transcripts absent from cell during nitrogen starvation" EXACT [PomBase:vw] synonym: "undetectable cellular RNA level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001152 ! decreased RNA level during nitrogen starvation is_a: FYPO:0001889 ! RNA absent from cell created_by: midori creation_date: 2013-02-25T16:35:43Z [Term] id: FYPO:0001997 name: abnormal nucleoside diphosphate kinase activity def: "A molecular function phenotype in which the observed rate of nucleoside diphosphate kinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-25T16:53:52Z [Term] id: FYPO:0001998 name: decreased nucleoside diphosphate kinase activity def: "A molecular function phenotype in which the observed rate of nucleoside diphosphate kinase activity is decreased." [PomBase:mah] synonym: "reduced nucleoside diphosphate kinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001997 ! abnormal nucleoside diphosphate kinase activity created_by: midori creation_date: 2013-02-25T16:53:59Z [Term] id: FYPO:0001999 name: increased nucleoside diphosphate kinase activity def: "A molecular function phenotype in which the observed rate of nucleoside diphosphate kinase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001997 ! abnormal nucleoside diphosphate kinase activity created_by: midori creation_date: 2013-02-25T16:54:09Z [Term] id: FYPO:0002000 name: inviable septated mononucleate vegetative cell alt_id: FYPO:0005276 def: "A cell phenotype in which a cell is inviable, and contains one nucleus and one or more septa. The nucleus is not in the normal location." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155), 'septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation' (FYPO:0003166), or their descendants, because these phenotypes often co-occur. synonym: "cytokinesis in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "cytokinesis without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable cell with cytokinesis in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable cell with cytokinesis without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable cell with premature septation" RELATED [PomBase:al, PomBase:vw] synonym: "inviable cell with septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable cell with septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "inviable cell with septation without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable septated mononucleate cell" EXACT [PomBase:vw] synonym: "inviable septated mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable septated mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable septated mononucleate vegetative cell with mislocalized nucleus" EXACT [PomBase:mah] synonym: "lethal; septated mononucleate vegetative cell" EXACT [PomBase:mah] synonym: "septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "septation without nuclear division" RELATED [PomBase:al, PomBase:vw] is_a: FYPO:0006430 ! inviable mononucleate vegetative cell is_a: FYPO:0007646 ! septated mononucleate vegetative cell with mislocalized nucleus and anucleate compartment relationship: has_part FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2013-02-27T13:08:58Z [Term] id: FYPO:0002002 name: multiseptate vegetative cell, septa grouped def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has one or more nuclei and more than one septum, and the septa are grouped together between two compartments, one or more of which may contain one or multiple nuclei." [PomBase:mah] synonym: "cytokinesis in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "cytokinesis without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "multiseptate cell, septa grouped, during vegetative growth" EXACT [PomBase:mah] synonym: "multiseptate vegetative cell, septa grouped during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "septation without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "vegetative cell with premature septation" RELATED [PomBase:al, PomBase:vw] is_a: FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2013-02-27T13:18:22Z [Term] id: FYPO:0002003 name: abolished RNA polymerase II proximal promoter sequence-specific DNA binding def: "A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. An RNA polymerase II proximal promoter is a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II." [GO:0000978, PomBase:mah] synonym: "abolished transcription factor binding to promoter region" RELATED [PomBase:al] synonym: "RNA polymerase II proximal promoter sequence-specific DNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2013-02-27T13:45:01Z [Term] id: FYPO:0002004 name: microtubules absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable microtubules of one or more types." [PomBase:mah] synonym: "absent microtubules" EXACT [PomBase:mah] synonym: "microtubules absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "microtubules absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2013-02-27T13:50:36Z [Term] id: FYPO:0002005 name: lobate nuclear envelope def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has a lobate cross-section, i.e. one in which the edge has deep indentations or undulations that form lobes." [http://en.wikipedia.org/wiki/File\:Leaf_morphology.svg&oldid=313835870, PMID:2211869, PomBase:mah] comment: This term differs from 'nuclear envelope protrusion present' (FYPO:0003788) in that a lobate envelope has a few deep fissures extending inward from the cytoplasm that appear to partially divide the nucleus into portions, whereas protrusions are smaller and extend outward from the bulk of the nucleus. synonym: "leaf-like nuclear envelope morphology" RELATED [PomBase:al] synonym: "lobate nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lobate nuclear envelope during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2013-02-27T14:11:12Z [Term] id: FYPO:0002006 name: increased cellular iron level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ions measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular iron ion level" EXACT [PomBase:mah] synonym: "increased cellular iron level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular iron level during vegetative growth" EXACT [PomBase:mah] synonym: "increased iron accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-02-27T14:37:50Z [Term] id: FYPO:0002007 name: abnormal chromosome morphology, single irregular mass def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosomes form a single, irregularly-shaped mass in the nucleus." [PMID:19074598, PomBase:mah] synonym: "abnormal chromatin organization with single irregular mass of chromatin" RELATED [PomBase:vw] synonym: "abnormal chromosome morphology, single irregular mass during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromosome morphology, single irregular mass during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2013-02-28T12:01:30Z [Term] id: FYPO:0002008 name: decreased aconitate hydratase activity def: "A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is decreased." [PomBase:mah] synonym: "decreased aconitase activity" EXACT [GO:0003994] synonym: "reduced aconitate hydratase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000920 ! abnormal aconitate hydratase activity created_by: midori creation_date: 2013-02-27T14:47:26Z [Term] id: FYPO:0002009 name: decreased oxygen consumption during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is lower than in wild type." [PomBase:mah] comment: Also see 'decreased cellular respiration' (FYPO:0000342). synonym: "decreased oxygen consumption during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased oxygen uptake during vegetative growth" RELATED [PomBase:vw] synonym: "reduced oxygen consumption during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2013-02-27T14:50:33Z [Term] id: FYPO:0002010 name: increased level of iron ion starvation-induced proteins def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced during iron ion starvation measured in a cell is higher than normal." [PomBase:mah] synonym: "increased level of iron ion depletion-induced proteins" EXACT [PomBase:vw] synonym: "increased level of iron ion deprivation-induced proteins" EXACT [PomBase:vw] synonym: "increased level of iron ion starvation-induced proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of iron ion starvation-induced proteins during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of proteins expressed during iron ion starvation" EXACT [PomBase:mah] synonym: "increased level of proteins induced by iron ion starvation" EXACT [PomBase:mah] synonym: "increased protein level of genes (normally) induced during iron starvation" EXACT [PomBase:al] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2013-02-27T14:56:22Z [Term] id: FYPO:0002011 name: increased level of hydrogen peroxide-induced proteins during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced by exposure to hydrogen peroxide measured in a cell is higher than normal." [PomBase:mah] synonym: "increased level of H2O2-induced proteins during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of hydrogen peroxide-induced proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of proteins expressed during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of proteins induced by hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level of genes (normally) induced during H2O2 stress during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2013-02-27T14:59:57Z [Term] id: FYPO:0002012 name: decreased level of iron ion starvation-repressed proteins def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally repressed during iron ion starvation measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased level of iron ion depletion-repressed proteins" EXACT [PomBase:vw] synonym: "decreased level of iron ion deprivation-repressed proteins" EXACT [PomBase:vw] synonym: "decreased level of iron ion starvation-repressed proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of iron ion starvation-repressed proteins during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of proteins repressed by iron ion starvation" EXACT [PomBase:mah] synonym: "decreased level of proteins repressed during iron ion starvation" EXACT [PomBase:mah] synonym: "decreased protein level of genes (normally) repressed during iron starvation" EXACT [PomBase:al] synonym: "reduced level of iron ion starvation-repressed proteins" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2013-02-27T15:03:13Z [Term] id: FYPO:0002013 name: normal protein oxidation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oxidation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein oxidation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide oxidation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2013-02-27T15:20:19Z [Term] id: FYPO:0002014 name: increased RNA level during cellular response to iron ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to iron ion starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to iron ion starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to iron ion starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to iron ion depletion" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to iron ion deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to iron ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to iron ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to iron starvation" EXACT [PomBase:mah] synonym: "increased RNA level during iron ion starvation" EXACT [PomBase:al] synonym: "increased transcript level during cellular response to iron ion starvation" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0003196 ! altered RNA level during cellular response to iron ion starvation created_by: midori creation_date: 2013-02-27T15:22:02Z [Term] id: FYPO:0002015 name: sensitive to iron ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to iron ion starvation." [PomBase:mah] synonym: "decreased growth during cellular response to iron ion starvation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to iron ion starvation" EXACT [PomBase:mah] synonym: "hypersensitive to iron ion starvation" EXACT [PomBase:mah] synonym: "sensitive to iron ion depletion" EXACT [PomBase:vw] synonym: "sensitive to iron ion deprivation" EXACT [PomBase:vw] synonym: "sensitive to iron ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to iron ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to iron starvation" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2013-02-27T15:24:45Z [Term] id: FYPO:0002016 name: sensitive to oxygen def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxygen. Cells stop growing (and may die) at a level of oxygen that allows wild type cells to grow." [PomBase:mah] comment: Also consider the term 'sensitive to oxidative stress' (FYPO:0000726). synonym: "hypersensitive to oxygen" EXACT [PomBase:mah] synonym: "sensitive to elemental oxygen" EXACT [CHEBI:33262, PomBase:mah] synonym: "sensitive to oxygen during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to oxygen during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-02-27T15:36:25Z [Term] id: FYPO:0002017 name: abnormal cell cycle arrest in mitotic interphase before NETO def: "A cellular process phenotype in which the mitotic cell cycle is arrested during G2 phase, before new end take-off (NETO) has occurred, under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormal cell cycle arrest in interphase before NETO during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic interphase before activation of bipolar cell growth" RELATED [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic interphase before cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "abnormal cell cycle arrest in mitotic interphase before NETO during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic interphase before new end take-off" RELATED [GO:0051519] synonym: "abnormal cell cycle arrest in mitotic interphase before switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in interphase before NETO" EXACT [PomBase:mah] synonym: "cell cycle arrest in mitotic interphase before NETO" BROAD [PomBase:vw] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase relationship: has_output FYPO:0001018 ! abolished NETO created_by: midori creation_date: 2013-02-27T15:46:41Z [Term] id: FYPO:0002018 name: mitotic spindle absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable mitotic spindle." [PomBase:mah] synonym: "absent mitotic spindle" EXACT [PomBase:mah] synonym: "mitotic spindle absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "spindle absent from cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2013-02-27T15:54:06Z [Term] id: FYPO:0002019 name: elongated telomeres during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are longer than normal." [PomBase:mah] synonym: "elongated telomeres during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased telomere length during vegetative growth" EXACT [PomBase:mah] synonym: "long telomeres during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006464 ! abnormal telomere length during vegetative growth created_by: midori creation_date: 2013-02-28T13:34:43Z [Term] id: FYPO:0002020 name: increased RNA level during nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to nitrogen starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "increased RNA level during nitrogen depletion" EXACT [PomBase:vw] synonym: "increased RNA level during nitrogen deprivation" EXACT [PomBase:vw] synonym: "increased transcript level during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0001890 ! increased RNA level is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation created_by: midori creation_date: 2013-02-28T13:42:00Z [Term] id: FYPO:0002021 name: dispersed actin cortical patch localization during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized throughout the cell cortex (rather than concentrated at the cell ends as in wild type cells)." [PMID:8834798, PomBase:mah] synonym: "delocalised actin cortical patches during vegetative growth" EXACT [PomBase:vw] synonym: "delocalized actin cortical patches during vegetative growth" EXACT [PomBase:vw] synonym: "depolarized actin cortical patch localization during vegetative growth" EXACT [PomBase:vw] synonym: "dispersed actin cortical patch localisation during vegetative growth" EXACT [PomBase:mah] synonym: "dispersed actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "dispersed actin cortical patch location during vegetative growth" RELATED [PomBase:mah] synonym: "dispersed actin patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "dispersed F-actin patch localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003988 ! mislocalized actin cortical patches during vegetative growth created_by: midori creation_date: 2013-02-28T13:54:07Z [Term] id: FYPO:0002022 name: normal actin cortical patch morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of actin cortical patches are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin cortical patch morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actin cortical patch morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal actin patch morphology" EXACT [PomBase:mah] synonym: "normal F-actin patch morphology" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2013-02-28T13:57:25Z [Term] id: FYPO:0002023 name: abnormal septum morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the septum is abnormal." [PomBase:mah] comment: Note that an abnormal septum organization process may, but does not necessarily, result in abnormal septum morphology. synonym: "abnormal septum morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002455 ! abnormal septum during vegetative growth relationship: output_of FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2013-02-28T14:08:39Z [Term] id: FYPO:0002024 name: inviable elongated multinucleate aseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, is elongated, has no septum, and contains more than one nucleus." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated multinucleate aseptate inviable vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated multinucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated multinucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated multinucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "septation initiation defective" RELATED [] synonym: "sid" RELATED [] is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0002049 ! elongated multinucleate aseptate vegetative cell is_a: FYPO:0002066 ! inviable elongated aseptate cell is_a: FYPO:0004106 ! inviable multinucleate aseptate vegetative cell created_by: midori creation_date: 2013-02-28T14:14:17Z [Term] id: FYPO:0002025 name: inviable elongated multinucleate vegetative cell with abnormal septum morphology def: "A cell morphology phenotype in which a vegetative cell is inviable, is elongated, contains a septum with abnormal morphology (i.e. size, shape, or structure), and contain more than one nucleus." [PMID:8834798, PomBase:mah] comment: In cells with this phenotype, an abnormal septum forms on the surface from one side of the cell and then extends in a disorganized manner into the interior. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated multinucleate inviable vegetative cell with abnormal septum morphology" EXACT [PomBase:mah] synonym: "inviable elongated multinucleate cell with abnormal septum morphology during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated multinucleate vegetative cell with abnormal septum morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated multinucleate vegetative cell with abnormal septum morphology" EXACT [PomBase:mah] is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth is_a: FYPO:0002889 ! inviable elongated vegetative cell with abnormal septum relationship: has_part FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2013-02-28T14:18:31Z [Term] id: FYPO:0002026 name: actomyosin contractile ring displaced from midpoint def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring that is perpendicular to the long axis of the cell, but is not located at the midpoint of the long axis." [PMID:8834798, PomBase:mah] synonym: "actomyosin contractile ring displaced from cell center" EXACT [PomBase:mah] synonym: "actomyosin contractile ring displaced from cell centre" EXACT [PomBase:mah] synonym: "actomyosin contractile ring displaced from cell midpoint" EXACT [PomBase:vw] synonym: "actomyosin contractile ring displaced from midpoint during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actomyosin contractile ring displaced from midpoint during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinetic contractile ring displaced from midpoint" EXACT [PomBase:vw] is_a: FYPO:0001369 ! mislocalized actomyosin contractile ring created_by: midori creation_date: 2013-02-28T15:34:27Z [Term] id: FYPO:0002027 name: angled actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring that is not perpendicular to the long axis of the cell." [PMID:8834798, PomBase:mah] comment: Note that a cell that has this phenotype will usually also subsequently display the phenotype 'binucleate monoseptate cell, with angled septum' (FYPO:0002156). synonym: "actomyosin contractile ring not orthogonal to long axis of cell" EXACT [PomBase:mah] synonym: "actomyosin contractile ring not perpendicular to long axis of cell" RELATED [PomBase:mah] synonym: "angled actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "angled actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "angled cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "angled mitotic contractile ring" EXACT [PomBase:vw] synonym: "tilted actomyosin contractile ring" EXACT [PMID:8834798] is_a: FYPO:0001369 ! mislocalized actomyosin contractile ring created_by: midori creation_date: 2013-02-28T15:43:06Z [Term] id: FYPO:0002028 name: multiple actomyosin contractile rings present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one actomyosin contractile ring." [PMID:8834798, PomBase:mah] synonym: "actomyosin contractile rings present in greater numbers" EXACT [PomBase:mah] synonym: "multiple actomyosin contractile rings present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiple actomyosin contractile rings present during vegetative growth" EXACT [PomBase:mah] synonym: "multiple cytokinetic contractile rings present" EXACT [PomBase:vw] synonym: "multiple mitotic contractile rings present" EXACT [PomBase:vw] is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth created_by: midori creation_date: 2013-02-28T15:45:46Z [Term] id: FYPO:0002029 name: abnormal cell division, large and small daughter cells def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cell divides asymmetrically, resulting in the formation of daughter cells that are not the same size." [PMID:8834798, PomBase:mah] synonym: "abnormal cell division, large and small daughter cells during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell division, large and small daughter cells during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000186 ! abnormal cell division during vegetative growth relationship: output_of FYPO:0000033 ! abnormal actomyosin contractile ring localization created_by: midori creation_date: 2013-02-28T15:54:13Z [Term] id: FYPO:0002030 name: abnormal actin cable organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cable organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cable. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [GO:0070648, PomBase:mah] synonym: "abnormal actin cable organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cable organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cable organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal formin-nucleated actin cable organization during vegetative growth" EXACT [GO:0070648] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2013-02-28T16:07:31Z [Term] id: FYPO:0002031 name: abnormal actin cable morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] synonym: "abnormal actin cable morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cable morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal formin-nucleated actin cable morphology" EXACT [GO:0070648] synonym: "disorganized actin cables" EXACT [PomBase:vw] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology during vegetative growth relationship: output_of FYPO:0002030 ! abnormal actin cable organization created_by: midori creation_date: 2013-02-28T16:07:51Z [Term] id: FYPO:0002032 name: abnormal actin cable morphology during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cables is abnormal during mitosis. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] synonym: "abnormal actin cable morphology during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cable morphology during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cable morphology during mitotic M phase" RELATED [PomBase:mah] synonym: "abnormal actin cable morphology during mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal formin-nucleated actin cable morphology during mitosis" EXACT [GO:0070648] synonym: "disorganized actin cables during mitosis" EXACT [PomBase:vw] is_a: FYPO:0002031 ! abnormal actin cable morphology created_by: midori creation_date: 2013-02-28T16:27:15Z [Term] id: FYPO:0002033 name: abolished protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein phosphorylation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0000775 ! abnormal protein phosphorylation during vegetative growth is_a: FYPO:0002678 ! abolished protein phosphorylation created_by: midori creation_date: 2013-02-28T16:31:47Z [Term] id: FYPO:0002034 name: abnormal DNA topoisomerase type I activity def: "A molecular function phenotype in which the observed rate of DNA topoisomerase type I activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-28T16:34:22Z [Term] id: FYPO:0002035 name: decreased DNA topoisomerase type I activity def: "A molecular function phenotype in which the observed rate of DNA topoisomerase type I activity is decreased." [PomBase:mah] synonym: "reduced DNA topoisomerase type I activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002034 ! abnormal DNA topoisomerase type I activity created_by: midori creation_date: 2013-02-28T16:34:29Z [Term] id: FYPO:0002036 name: abnormal endodeoxyribonuclease activity def: "A molecular function phenotype in which the observed rate of an endodeoxyribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-02-28T16:37:28Z [Term] id: FYPO:0002037 name: decreased endodeoxyribonuclease activity def: "A molecular function phenotype in which the observed rate of an endodeoxyribonuclease activity is decreased." [PomBase:mah] synonym: "reduced endodeoxyribonuclease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002036 ! abnormal endodeoxyribonuclease activity created_by: midori creation_date: 2013-02-28T16:37:38Z [Term] id: FYPO:0002038 name: abnormal deadenylation-independent decapping of nuclear-transcribed mRNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deadenylation-independent decapping of nuclear-transcribed mRNA is abnormal. This decapping process is cleavage of the 5'-cap of a nuclear-transcribed mRNA, independent of poly(A) tail shortening. All RNA decapping may be abnormal, or one or more specific RNA molecules may be selectively affected." [GO:0031087, PomBase:mah] synonym: "abnormal deadenylation-independent decapping of nuclear-transcribed mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal deadenylation-independent decapping of nuclear-transcribed mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth is_a: FYPO:0004851 ! abnormal RNA metabolic process created_by: midori creation_date: 2013-03-08T11:32:33Z [Term] id: FYPO:0002039 name: decreased deadenylation-independent decapping of nuclear-transcribed mRNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of deadenylation-independent decapping of nuclear-transcribed mRNA is decreased. All RNA decapping may be decreased, or one or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "decreased deadenylation-independent decapping of nuclear-transcribed mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased deadenylation-independent decapping of nuclear-transcribed mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "reduced deadenylation-independent decapping of nuclear-transcribed mRNA" EXACT [PomBase:mah] is_a: FYPO:0002038 ! abnormal deadenylation-independent decapping of nuclear-transcribed mRNA created_by: midori creation_date: 2013-03-08T11:33:11Z [Term] id: FYPO:0002040 name: increased deadenylation-independent decapping of nuclear-transcribed mRNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of deadenylation-independent decapping of nuclear-transcribed mRNA is increased. All RNA decapping may be increased, or one or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "increased deadenylation-independent decapping of nuclear-transcribed mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased deadenylation-independent decapping of nuclear-transcribed mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002038 ! abnormal deadenylation-independent decapping of nuclear-transcribed mRNA created_by: midori creation_date: 2013-03-08T11:33:36Z [Term] id: FYPO:0002041 name: abolished deadenylation-independent decapping of nuclear-transcribed mRNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deadenylation-independent decapping of nuclear-transcribed mRNA does not occur. All RNA decapping may be abolished, or one or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "abolished deadenylation-independent decapping of nuclear-transcribed mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent deadenylation-independent decapping of nuclear-transcribed mRNA" EXACT [PomBase:mah] synonym: "deadenylation-independent decapping of nuclear-transcribed mRNA abolished" EXACT [PomBase:mah] synonym: "deadenylation-independent decapping of nuclear-transcribed mRNA abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002038 ! abnormal deadenylation-independent decapping of nuclear-transcribed mRNA created_by: midori creation_date: 2013-03-08T11:33:48Z [Term] id: FYPO:0002042 name: decreased RNA level during cellular response to iron ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to iron ion starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to iron ion starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to iron ion starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to iron ion depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to iron ion deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to iron ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to iron ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to iron starvation" EXACT [GO:0036225, PomBase:mah] synonym: "decreased RNA level during iron ion starvation" EXACT [PomBase:al] synonym: "decreased transcript level during cellular response to iron ion starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to iron ion starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0003196 ! altered RNA level during cellular response to iron ion starvation created_by: midori creation_date: 2013-03-14T15:30:48Z [Term] id: FYPO:0002043 name: normal premeiotic DNA replication def: "A cellular process phenotype in which premeiotic DNA replication is normal." [PomBase:mah] synonym: "abnormal premeiotic DNA synthesis" RELATED [GO:0006279, GOC:mah] synonym: "normal meiotic DNA replication" RELATED [GO:0006279, GOC:mah] synonym: "normal meiotic DNA synthesis" RELATED [GO:0006279, GOC:mah] is_a: FYPO:0001133 ! normal DNA replication created_by: midori creation_date: 2013-03-14T15:45:15Z [Term] id: FYPO:0002044 name: abolished premeiotic DNA replication def: "A cellular process phenotype in which premeiotic DNA replication does not occur." [PomBase:mah] synonym: "absent premeiotic DNA replication" EXACT [PomBase:mah] synonym: "premeiotic DNA replication abolished" EXACT [PomBase:mah] is_a: FYPO:0000625 ! abnormal premeiotic DNA replication created_by: midori creation_date: 2013-03-14T15:48:07Z [Term] id: FYPO:0002045 name: resistance to heat shock def: "A cell phenotype in which cells show decreased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "increased cell population growth during cellular response to heat shock" EXACT [PomBase:mah] synonym: "increased growth during cellular response to heat shock" EXACT [PomBase:mah] synonym: "resistant to heat shock" EXACT [PomBase:mah] is_a: FYPO:0002046 ! resistance to stress created_by: midori creation_date: 2013-03-14T15:54:13Z [Term] id: FYPO:0002046 name: resistance to stress def: "A phenotype in which cells in a population show decreased sensitivity to a stress. Typically, a cell population is deemed resistant to a stress if cells in the population grow and divide when exposed to the stress at an intensity at which wild-type cells stop growing (and may die)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Use a descendant of this term if you have assayed growth of cells exposed to a stress in culture. If you have assayed the response to the stress at the subcellular or molecular level, consider annotating to a descendant of 'abnormal cellular response to stress' (FYPO:0000162). subset: qc_do_not_manually_annotate synonym: "increased cell population growth during cellular response to stress" EXACT [PomBase:mah] synonym: "increased growth during cellular response to stress" EXACT [PomBase:mah] synonym: "resistant to stress" EXACT [PomBase:mah] synonym: "stress resistance: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000045 ! abnormal cell population growth created_by: midori creation_date: 2013-03-14T15:56:42Z [Term] id: FYPO:0002047 name: resistance to heat shock during nitrogen starvation def: "A cell phenotype in which cells show decreased sensitivity to heat shock, when the cell is also subject to nitrogen starvation. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "increased cell population growth during cellular response to heat shock during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased growth during cellular response to heat shock during nitrogen starvation" EXACT [PomBase:mah] synonym: "resistance to heat shock during nitrogen depletion" EXACT [PomBase:vw] synonym: "resistance to heat shock during nitrogen deprivation" EXACT [PomBase:vw] synonym: "resistant to heat shock during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002045 ! resistance to heat shock created_by: midori creation_date: 2013-03-14T16:00:03Z [Term] id: FYPO:0002048 name: normal cell morphology during nitrogen starvation alt_id: FYPO:0001957 alt_id: FYPO:0001958 def: "A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is subject to nitrogen starvation. Wild-type cells become spherical upon nitrogen starvation, and have a smaller volume than under nitrogen-replete conditions." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "cell morphology, round cells during nitrogen starvation" RELATED [PomBase:mah] synonym: "cell morphology, rounded cells during nitrogen starvation" RELATED [PomBase:mah] synonym: "normal cell morphology during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal cell morphology during nitrogen deprivation" EXACT [PomBase:vw] synonym: "orb during nitrogen starvation" EXACT [PomBase:jh, PomBase:vw] synonym: "rounded cell during nitrogen starvation" RELATED [PomBase:mah] synonym: "small spherical cell during nitrogen starvation" EXACT [PomBase:vw] synonym: "spherical cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "spherical cell during nitrogen deprivation" EXACT [PomBase:vw] synonym: "spherical cell during nitrogen starvation" EXACT [PomBase:vw] synonym: "spheroid cell during nitrogen depletion" RELATED [PomBase:vw] synonym: "spheroid cell during nitrogen deprivation" RELATED [PomBase:vw] synonym: "spheroid cell during nitrogen starvation" RELATED [PomBase:vw] is_a: FYPO:0000672 ! normal cell morphology created_by: midori creation_date: 2013-03-14T16:29:43Z [Term] id: FYPO:0002049 name: elongated multinucleate aseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is elongated, has no septum, and contains more than one nucleus." [PomBase:mah] synonym: "elongated multinucleate aseptate cells during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0000950 ! elongated aseptate vegetative cell created_by: midori creation_date: 2013-03-14T16:36:18Z [Term] id: FYPO:0002050 name: branched elongated multinucleate aseptate vegetative cell def: "A cell morphology phenotype in which vegetative a cell is branched, elongated, has no septum, and contains more than one nucleus." [PomBase:mah] synonym: "branched elongated multinucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched elongated multinucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001512 ! branched, elongated cell is_a: FYPO:0002049 ! elongated multinucleate aseptate vegetative cell created_by: midori creation_date: 2013-03-14T16:40:20Z [Term] id: FYPO:0002051 name: swollen elongated multinucleate aseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is swollen, elongated, has no septum, and contains more than one nucleus. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "elongated multinucleate aseptate vegetative cell with increased cell volume" EXACT [PomBase:mah] synonym: "enlarged elongated multinucleate aseptate vegetative cell" RELATED [PomBase:mah] synonym: "large elongated multinucleate aseptate vegetative cell" RELATED [PomBase:mah] synonym: "swollen elongated multinucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "swollen elongated multinucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001429 ! swollen elongated cell is_a: FYPO:0002049 ! elongated multinucleate aseptate vegetative cell is_a: FYPO:0004257 ! swollen multinucleate vegetative cell created_by: midori creation_date: 2013-03-14T16:41:21Z [Term] id: FYPO:0002052 name: normal sporulation frequency def: "A cell population phenotype in which the frequency of occurrence of ascospore formation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal ascospore formation frequency" EXACT [PomBase:mah] synonym: "normal sporulation occurrence" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2013-03-15T16:28:36Z [Term] id: FYPO:0002053 name: normal DNA topoisomerase II activity def: "A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity" EXACT [GO:0003918] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2013-03-26T15:48:36Z [Term] id: FYPO:0002054 name: obsolete cut during cellular response to hydroxyurea def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to hydroxyurea. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to HU" EXACT [PomBase:mah] synonym: "cut during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2013-03-27T16:33:44Z [Term] id: FYPO:0002055 name: obsolete inviable cell at low temperature def: "OBSOLETE. A viability phenotype in which a cell is unable to survive at a low temperature at which wild-type cells survive." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the cell viability term with conditions specified. synonym: "lethal in cell at low temperature" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-03-27T16:52:52Z [Term] id: FYPO:0002056 name: decreased mitochondrial translation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial translation is decreased." [PomBase:mah] comment: Note that this term should be used only when an experiment measures mitochondrial protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "decreased mitochondrial protein biosynthesis" EXACT [GO:0032543] synonym: "decreased mitochondrial protein synthesis" EXACT [GO:0032543] synonym: "decreased mitochondrial translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial translation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of mitochondrial protein synthesis" RELATED [PomBase:mah] synonym: "reduced mitochondrial translation" EXACT [PomBase:mah] is_a: FYPO:0001798 ! decreased translation is_a: FYPO:0004528 ! abnormal mitochondrial translation created_by: midori creation_date: 2013-03-27T16:55:57Z [Term] id: FYPO:0002057 name: cell population viability def: "A cell population phenotype that reflects the proportion of the population that survive and develop normally." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2013-04-04T13:48:22Z [Term] id: FYPO:0002058 name: viable cell population def: "A cell population phenotype in which cells in the population are viable." [PomBase:mah] comment: Note that a viable population may contain individual cells that are inviable. Usually it is difficult to detect inviable cells within an otherwise viable population, especially if population growth is simply assayed by OD increase in liquid culture or by colony formation on plates. If you have done an experiment that detects individual inviable cells, consider using the term 'mixed population including viable and inviable cells' (FYPO:0000908). is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2013-04-04T13:51:27Z [Term] id: FYPO:0002059 name: inviable cell population def: "A cell population phenotype in which none of the cells in the population are viable." [PomBase:mah] synonym: "essential" RELATED [PomBase:al] synonym: "lethal in cell population" EXACT [PomBase:mah] is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2013-04-04T13:54:32Z [Term] id: FYPO:0002060 name: viable vegetative cell population def: "A cell population phenotype in which cells in the population are viable in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "viable cell population during vegetative growth" EXACT [PomBase:mah] synonym: "viable vegetative cell population during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2013-04-04T14:14:35Z [Term] id: FYPO:0002061 name: inviable vegetative cell population def: "A cell population phenotype in which all cells in the population are inviable in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "essential in vegetative cell population" RELATED [PomBase:al] synonym: "inviable" BROAD [PomBase:mlr] synonym: "inviable cell population during vegetative growth" EXACT [PomBase:mah] synonym: "inviable population" BROAD [PomBase:mlr] synonym: "inviable vegetative cell population during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal" BROAD [PomBase:mlr] synonym: "lethal in vegetative cell population" EXACT [PomBase:mah] synonym: "lethal population" BROAD [PomBase:mlr] is_a: FYPO:0002059 ! inviable cell population created_by: midori creation_date: 2013-04-04T14:15:53Z [Term] id: FYPO:0002062 name: normal cell growth def: "A cellular process phenotype in which the growth of a cell is normal (i.e. indistinguishable from wild type). Cell growth is the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GO:0016049, PomBase:mah] comment: Note that this term refers to growth at the level of any individual cell, and that it specifies only that increase in cell size due to metabolism is normal. Other aspects of the cell's biology may be abnormal, and other abnormalities may affect increase in cell number (population growth). Also see 'cell population growth phenotype' (FYPO:0000139) and its descendants. is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2013-04-05T14:44:50Z [Term] id: FYPO:0002063 name: abnormal 3'-5'-exoribonuclease activity def: "A molecular function phenotype in which the observed rate of a 3'-5'-exoribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-04-05T15:31:48Z [Term] id: FYPO:0002064 name: abolished 3'-5'-exoribonuclease activity def: "A molecular function phenotype in which a 3'-5'-exoribonuclease activity is absent." [PomBase:mah] synonym: "3'-5'-exoribonuclease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002063 ! abnormal 3'-5'-exoribonuclease activity created_by: midori creation_date: 2013-04-05T15:31:56Z [Term] id: FYPO:0002065 name: normal 3'-5'-exoribonuclease activity def: "A molecular function phenotype in which the observed rate of a 3'-5'-exoribonuclease activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2013-04-05T15:32:29Z [Term] id: FYPO:0002066 name: inviable elongated aseptate cell def: "A cell phenotype in which a cell has no septum, is elongated, and is inviable." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable elongated aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable long aseptate cell" EXACT [PomBase:vw] synonym: "lethal; elongated aseptate cell" EXACT [PomBase:mah] is_a: FYPO:0000950 ! elongated aseptate vegetative cell is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0003931 ! inviable aseptate vegetative cell created_by: midori creation_date: 2013-04-17T14:42:57Z [Term] id: FYPO:0002067 name: slow cell population growth during recovery from stationary phase def: "A cell population phenotype in which a cell population grows more slowly than normal when the population has been in stationary phase and is then placed in conditions that allow recovery." [PomBase:mah] is_a: FYPO:0001234 ! slow vegetative cell population growth created_by: midori creation_date: 2013-04-17T15:03:47Z [Term] id: FYPO:0002068 name: growth auxotrophic for histidine def: "Auxotrophy in which a cell is unable to synthesize histidine, and therefore requires histidine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for histidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for histidine during vegetative growth" EXACT [PomBase:mah] synonym: "histidine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2013-04-17T16:06:19Z [Term] id: FYPO:0002069 name: mislocalized nucleus def: "A physical cellular phenotype in which a cell has a nucleus in an abnormal location. The normal location is at the midpoint of the long axis of the cell." [PomBase:mah] synonym: "abnormal nucleus location" EXACT [PomBase:mah] synonym: "abnormal nucleus position" EXACT [PomBase:mah] synonym: "displaced nucleus" EXACT [PomBase:vw] synonym: "mislocalised nucleus" EXACT [PomBase:mah] synonym: "misplaced nuclei" EXACT [PomBase:vw] synonym: "misplaced nucleus" EXACT [PomBase:vw] synonym: "nuclear displacement" EXACT [PomBase:vw] synonym: "nuclear position: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000136 ! cellular physical quality phenotype relationship: output_of FYPO:0000517 ! abnormal nucleus positioning created_by: midori creation_date: 2013-04-17T16:12:37Z [Term] id: FYPO:0002070 name: normal nucleus location def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a nucleus in the normal location at the midpoint of the long axis of the cell." [PomBase:mah] synonym: "normal nuclear location" EXACT [PomBase:mah] synonym: "normal nucleus location during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleus location during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleus position" EXACT [PomBase:mah] synonym: "normally localized nucleus" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component relationship: output_of FYPO:0001389 ! normal nucleus positioning created_by: midori creation_date: 2013-04-17T16:16:17Z [Term] id: FYPO:0002071 name: mislocalized nucleus during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a nucleus in an abnormal location. The normal location of a single nucleus is at the midpoint of the long axis of the cell (during mitotic telophase, daughter nuclei normally move away from the cell division site)." [PomBase:mah] synonym: "abnormal nucleus location during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleus position during vegetative growth" EXACT [PomBase:mah] synonym: "displaced nucleus during vegetative growth" EXACT [PomBase:vw] synonym: "mislocalised nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "misplaced nuclei during vegetative growth" EXACT [PomBase:vw] synonym: "misplaced nucleus during vegetative growth" EXACT [PomBase:vw] synonym: "nuclear displacement during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0002069 ! mislocalized nucleus relationship: output_of FYPO:0001338 ! abnormal nucleus positioning during vegetative growth created_by: midori creation_date: 2013-04-17T16:20:51Z [Term] id: FYPO:0002072 name: mislocalized nucleus in prospore def: "A physical cellular phenotype in which a prospore has a nucleus in an abnormal location. The normal location is at the midpoint of the long axis of the cell." [PomBase:mah] synonym: "abnormal nucleus location in prospore" EXACT [PomBase:mah] synonym: "abnormal nucleus position in prospore" EXACT [PomBase:mah] synonym: "displaced nucleus in prospore" EXACT [PomBase:vw] synonym: "displaced nucleus prospore" EXACT [PomBase:vw] synonym: "mislocalised nucleus in prospore" EXACT [PomBase:mah] synonym: "mislocalized nucleus in forespore" EXACT [PomBase:mah] synonym: "mislocalized prospore nucleus" EXACT [PomBase:mah] synonym: "misplaced prospore nuclei" EXACT [PomBase:vw] synonym: "misplaced prospore nucleus" EXACT [PomBase:vw] synonym: "nuclear displacement in prospore" EXACT [PomBase:vw] is_a: FYPO:0002069 ! mislocalized nucleus relationship: output_of FYPO:0000942 ! abnormal nucleus positioning in prospore created_by: midori creation_date: 2013-04-17T16:23:48Z [Term] id: FYPO:0002073 name: protein mislocalized to nucleus during cellular response to copper ion def: "A cell phenotype in which a protein that is not normally found in the nucleus is observed there during a cellular response to copper ions." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleus during cellular response to copper" EXACT [PomBase:vw] synonym: "nuclear protein accumulation in response to copper" RELATED [PomBase:al] synonym: "protein mislocalised to nucleus during cellular response to copper ion" EXACT [PomBase:mah] synonym: "protein mislocalised to nucleus during cellular response to copper ion during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during cellular response to copper" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during cellular response to copper during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to nucleus during cellular response to copper ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2013-04-24T12:06:43Z [Term] id: FYPO:0002074 name: obsolete inviable cell population at high temperature def: "OBSOLETE. A cell population phenotype in which none of the cells in the population are viable at a high temperature." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. is_obsolete: true created_by: midori creation_date: 2013-04-24T12:29:02Z [Term] id: FYPO:0002075 name: obsolete inviable vegetative cell population at high temperature def: "OBSOLETE. A cell population phenotype in which none of the cells in the population are viable at a high temperature in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-04-24T12:31:01Z [Term] id: FYPO:0002076 name: inviable elongated cell with fragmented nucleus and increased septum thickness def: "A cell phenotype in which a cell is elongated, has a nucleus that is broken into multiple small fragments, forms a septum that is thicker than normal, and is inviable." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell with fragmented nuclear material and increased septum thickness" EXACT [PomBase:al] synonym: "elongated inviable cell with fragmented nuclei and increased septum thickness" EXACT [PomBase:al] synonym: "elongated inviable cell with fragmented nucleus and increased septum thickness" EXACT [PomBase:mah] synonym: "elongated inviable cell with fragmented nucleus and increased septum thickness during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated cell with fragmented nuclear DNA and increased septum thickness" RELATED [PomBase:mah] synonym: "inviable elongated cell with fragmented nucleus and increased septum thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated cell with fragmented nucleus and increased septum thickness" EXACT [PomBase:mah] synonym: "long inviable cell with fragmented nucleus and increased septum thickness" EXACT [PomBase:vw] is_a: FYPO:0001406 ! increased septum thickness is_a: FYPO:0002889 ! inviable elongated vegetative cell with abnormal septum is_a: FYPO:0004672 ! inviable elongated vegetative cell with fragmented nucleus relationship: has_part FYPO:0001406 ! increased septum thickness relationship: has_part FYPO:0001919 ! fragmented nucleus during vegetative growth created_by: midori creation_date: 2013-04-24T12:48:44Z [Term] id: FYPO:0002077 name: sensitive to low osmolarity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to conditions of low osmolarity." [PomBase:mah] synonym: "decreased growth during cellular response to low osmolarity" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to low osmolarity" EXACT [PomBase:mah] synonym: "hypersensitive to low osmolarity" EXACT [PomBase:mah] synonym: "sensitive to hypo-osmotic conditions" EXACT [PomBase:mah] synonym: "sensitive to hypoosmotic conditions" EXACT [PomBase:al] synonym: "sensitive to hypotonic conditions" RELATED [PomBase:mah] synonym: "sensitive to low osmolarity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to low osmolarity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress created_by: midori creation_date: 2013-04-24T14:41:45Z [Term] id: FYPO:0002078 name: sensitive to calcium during cellular hypotonic response def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium during a cellular hypotonic response. Cells stop growing (and may die) at a concentration of calcium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to calcium during cellular hypotonic response" EXACT [PomBase:mah] synonym: "sensitive to calcium during cellular hypoosmotic response" EXACT [PomBase:al] synonym: "sensitive to calcium during cellular hypotonic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to calcium during cellular hypotonic response during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to calcium ions during cellular hypotonic response" EXACT [PomBase:mah] is_a: FYPO:0000098 ! sensitive to calcium created_by: midori creation_date: 2013-04-24T14:57:12Z [Term] id: FYPO:0002079 name: normal growth on calcium during cellular hypotonic response def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing calcium ions during a cellular hypotonic response." [PomBase:mah] synonym: "normal cell population growth in presence of calcium ions during cellular hypotonic response" EXACT [PomBase:mah] synonym: "normal cell population growth on calcium during cellular hypotonic response" EXACT [PomBase:mah] synonym: "normal cell population growth on calcium ion during cellular hypoosmotic response" EXACT [PomBase:al] synonym: "normal cell population growth on calcium ion during cellular hypotonic response" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on excess calcium during cellular hypotonic response" EXACT [PomBase:al] synonym: "normal cellular response to calcium ion during cellular hypotonic response" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on calcium ion during cellular hypotonic response" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on calcium ion during cellular hypotonic response" EXACT [PomBase:mah] is_a: FYPO:0001020 ! normal growth on calcium created_by: midori creation_date: 2013-04-24T14:59:06Z [Term] id: FYPO:0002080 name: sensitive to TPCK def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK). Cells stop growing (and may die) at a concentration of TPCK that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to TPCK" EXACT [PomBase:mah] synonym: "sensitive to N-tosyl-L-phenylalanyl chloromethyl ketone" EXACT [CHEBI:9642, PomBase:mah] synonym: "sensitive to TPCK during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to TPCK during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001695 ! sensitive to protease inhibitor created_by: midori creation_date: 2013-05-01T15:43:45Z [Term] id: FYPO:0002081 name: normal growth on TPCK def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK)." [PomBase:mah] synonym: "normal cell population growth in presence of TPCK" EXACT [PomBase:mah] synonym: "normal cell population growth on N-tosyl-L-phenylalanyl chloromethyl ketone" EXACT [CHEBI:9642] synonym: "normal cell population growth on TPCK" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to TPCK" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on TPCK" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-05-01T15:45:35Z [Term] id: FYPO:0002082 name: increased protein ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is increased." [PomBase:mah] comment: Consider also annotating to 'increased level of ubiquitinated protein in cell during vegetative growth' (FYPO:0002774). We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein ubiquitinylation during vegetative growth" EXACT [GO:0016567, PomBase:mah] synonym: "increased protein ubiquitylation during vegetative growth" EXACT [GO:0016567, PomBase:mah] is_a: FYPO:0000905 ! abnormal protein ubiquitination during vegetative growth created_by: midori creation_date: 2013-05-01T15:54:55Z [Term] id: FYPO:0002083 name: inviable swollen elongated cell with enlarged nucleus def: "A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and in which the nucleus is larger than normal. The cell contains one nucleus and no septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PMID:10388806, PomBase:mah, PomBase:vw] comment: The distinction between this phenotype and centrally constricted (dumbbell-shaped) cells (FYPO:0000779) is that swollen elongated cells do not have a constriction along the long axis. Swollen elongated cells may have a uniform diameter, or may be swollen only around the nucleus. This phenotype is usually seen in diploid cells, so consider also annotating to 'increased spontaneous diploidization' (FYPO:0000252). synonym: "inviable elongated cell with enlarged nucleus and increased cell volume" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with swollen medial region" RELATED [PomBase:mah] synonym: "inviable enlarged elongated cell with enlarged nucleus" RELATED [PomBase:mah] synonym: "inviable large elongated cell with enlarged nucleus" RELATED [PomBase:vw] synonym: "inviable swollen elongated mononucleate aseptate cell with enlarged nucleus" EXACT [PomBase:vw] synonym: "inviable swollen elongated vegetative cell with enlarged nucleus" EXACT [PomBase:mah] synonym: "lethal; swollen elongated cell with enlarged nucleus" EXACT [PomBase:mah] is_a: FYPO:0002251 ! inviable swollen elongated vegetative cell is_a: FYPO:0005440 ! swollen elongated cell with enlarged nucleus created_by: midori creation_date: 2013-05-01T16:06:42Z [Term] id: FYPO:0002084 name: swollen stubby vegetative cell def: "A cell morphology phenotype in which a vegetative cell has a larger volume and cell diameter, but shorter cell length, than normal." [PomBase:mah] synonym: "enlarged stubby cell" RELATED [PomBase:mah] synonym: "large stubby cell" RELATED [PomBase:vw] synonym: "stubby cell with increased cell size" RELATED [PomBase:vw] synonym: "stubby cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen watermelon-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0000024 ! stubby vegetative cell is_a: FYPO:0000646 ! swollen vegetative cell relationship: has_part FYPO:0000024 ! stubby vegetative cell relationship: has_part FYPO:0000646 ! swollen vegetative cell created_by: midori creation_date: 2013-05-01T16:10:39Z [Term] id: FYPO:0002085 name: normal vegetative cell growth def: "A cellular process phenotype in which the growth of a cell is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. Cell growth is the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GO:0016049, PomBase:mah] comment: Note that this term refers to growth at the level of any individual cell, and that it specifies only that increase in cell size due to metabolism is normal. Other aspects of the cell's biology may be abnormal, and other abnormalities may affect increase in cell number (population growth). Also see 'cell population growth phenotype' (FYPO:0000139) and its descendants. is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0002062 ! normal cell growth created_by: midori creation_date: 2013-05-01T16:24:01Z [Term] id: FYPO:0002086 name: exocytic vesicles present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles than normal." [PomBase:mah] synonym: "accumulation of exocytic vesicles" RELATED [PomBase:vw] synonym: "additional exocytic vesicles present" EXACT [PomBase:mah] synonym: "exocytic vesicles present in greater numbers" EXACT [PomBase:mah] synonym: "exocytic vesicles present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "exocytic vesicles present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "exocytotic vesicles present in increased numbers" EXACT [GO:0070382] synonym: "extra exocytic vesicles" EXACT [PomBase:mah] synonym: "post-Golgi secretory vesicles present in increased numbers" RELATED [PomBase:vw] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0002089 ! abnormal exocytosis during vegetative growth created_by: midori creation_date: 2013-05-01T16:39:50Z [Term] id: FYPO:0002087 name: exocytic vesicles present in increased numbers at cell tip during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles at one or both cell tips than normal during interphase of the mitotic cell cycle, when the cell is growing." [PomBase:mah] synonym: "accumulation of exocytic vesicles at cell tip during mitotic interphase" RELATED [PomBase:vw] synonym: "additional exocytic vesicles present at cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "exocytic vesicles present in greater numbers at cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "exocytic vesicles present in increased numbers at cell end during mitotic interphase" EXACT [PomBase:mah] synonym: "exocytic vesicles present in increased numbers at cell tip during cell growth" EXACT [PomBase:vw] synonym: "exocytic vesicles present in increased numbers at cell tip during cell growth during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "exocytic vesicles present in increased numbers at cell tip during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "exocytotic vesicles present in increased numbers at cell tip during mitotic interphase" EXACT [GO:0070382] synonym: "extra exocytic vesicles at cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "post-Golgi secretory vesicles present in increased numbers at cell tip during mitotic interphase" RELATED [PomBase:vw] is_a: FYPO:0002086 ! exocytic vesicles present in increased numbers created_by: midori creation_date: 2013-05-01T16:43:15Z [Term] id: FYPO:0002088 name: exocytic vesicles present in increased numbers at septum during septum assembly def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles than normal near the division septum while the cell is undergoing septum assembly." [PomBase:mah] synonym: "accumulation of exocytic vesicles at division septum during septum assembly" RELATED [PomBase:vw] synonym: "additional exocytic vesicles present at division septum during septum assembly" EXACT [PomBase:mah] synonym: "exocytic vesicles present in greater numbers at division septum during septum assembly" EXACT [PomBase:mah] synonym: "exocytic vesicles present in increased numbers at division septum during mitotic telophase" RELATED [PomBase:vw] synonym: "exocytic vesicles present in increased numbers at division septum during septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "exocytic vesicles present in increased numbers at division septum during septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "exocytic vesicles present in increased numbers at septum during septation" BROAD [GO:0000917, PomBase:mah] synonym: "exocytotic vesicles present in increased numbers at division septum during septum assembly" EXACT [GO:0070382] synonym: "extra exocytic vesicles at division septum during septum assembly" EXACT [PomBase:mah] synonym: "post-Golgi secretory vesicles present in increased numbers at division septum during septum assembly" RELATED [PomBase:vw] is_a: FYPO:0002086 ! exocytic vesicles present in increased numbers created_by: midori creation_date: 2013-05-01T16:44:51Z [Term] id: FYPO:0002089 name: abnormal exocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which exocytosis is abnormal. Exocytosis is the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. A phenotype may affect exocytosis of all cargoes, or of specific cargo such as a particular protein." [GO:0006887, PomBase:mah] synonym: "abnormal exocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "exocytosis defects during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport during vegetative growth is_a: FYPO:0007873 ! abnormal exocytosis created_by: midori creation_date: 2013-05-01T16:47:54Z [Term] id: FYPO:0002090 name: lagging chromosomes def: "A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during nuclear division, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed." [PomBase:mah] comment: Chromosome lagging may reflect a delay in detachment of homologous chromosomes or sister chromatids from each other ('chromosome separation' as defined by GO:0051304), polewards movement (GO:0051305), or both. synonym: "chromosome segregation defects, lagging chromosomes" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation created_by: midori creation_date: 2013-05-01T16:58:26Z [Term] id: FYPO:0002091 name: lagging meiotic chromosomes def: "A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during meiosis I or meiosis II, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed." [PomBase:mah] comment: Chromosome lagging may reflect a delay in detachment of homologous chromosomes or sister chromatids from each other ('chromosome separation' as defined by GO:0051307), polewards movement (GO:0016344), or both. synonym: "chromosome segregation defects, lagging meiotic chromosomes" EXACT [PomBase:mah] synonym: "lagging chromosomes during meiosis" EXACT [PomBase:mah] synonym: "meiotic chromosome segregation defects, lagging chromosomes" EXACT [PomBase:mah] is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation is_a: FYPO:0002090 ! lagging chromosomes created_by: midori creation_date: 2013-05-01T16:59:42Z [Term] id: FYPO:0002092 name: abnormal meiotic sister chromatid cohesion def: "A cellular process phenotype in which cohesion between sister chromatids is abnormal during meiosis." [PomBase:mah] synonym: "abnormal sister chromatid cohesion during meiosis" EXACT [PomBase:mah] is_a: FYPO:0006759 ! abnormal meiotic chromosome organization is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle relationship: part_of FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2013-05-01T17:08:24Z [Term] id: FYPO:0002093 name: decreased meiotic sister chromatid cohesion def: "A cellular process phenotype in which cohesion between sister chromatids is decreased during meiosis." [PomBase:mah] comment: Abnormal cohesion may cause separation of sister chromatids during the first meiotic nuclear division, leading to equational segregation. If this occurs, also annotate to 'equational sister chromatid separation during meiosis I' (FYPO:0005634). synonym: "decreased sister chromatid cohesion during meiosis" EXACT [PomBase:mah] synonym: "reduced meiotic sister chromatid cohesion" EXACT [PomBase:mah] is_a: FYPO:0002092 ! abnormal meiotic sister chromatid cohesion created_by: midori creation_date: 2013-05-01T17:09:24Z [Term] id: FYPO:0002094 name: normal meiotic sister chromatid cohesion def: "A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) during meiosis." [PomBase:mah] synonym: "normal sister chromatid cohesion during meiosis" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2013-05-01T17:12:15Z [Term] id: FYPO:0002095 name: increased protein phosphorylation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to a DNA damage stimulus." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to DNA damaging agent" RELATED [PomBase:al] synonym: "increased protein phosphorylation during response to DNA damage stimulus" EXACT [GO:0006974] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-05-02T11:57:21Z [Term] id: FYPO:0002096 name: increased protein phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to hydroxyurea." [PomBase:mah] comment: Also consider annotating to 'increased protein phosphorylation during cellular response to DNA damage' (FYPO:0002095). When using this term, it is recommended to note the specific protein(s) affected. synonym: "increased protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-05-02T12:12:21Z [Term] id: FYPO:0002097 name: decreased protein kinase activity during cellular response to hydroxyurea def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to hydroxyurea." [PomBase:mah] synonym: "decreased protein kinase activity during cellular response to HU" EXACT [PomBase:mah] synonym: "reduced protein kinase activity during cellular response to HU" EXACT [PomBase:mah] synonym: "reduced protein kinase activity during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2013-05-02T12:21:11Z [Term] id: FYPO:0002098 name: decreased protein phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-05-02T12:23:07Z [Term] id: FYPO:0002099 name: normal protein phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-05-02T12:25:08Z [Term] id: FYPO:0002100 name: abnormal 3'-5' DNA helicase activity def: "A molecular function phenotype in which the observed rate of an 3'-5' DNA helicase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-05-02T12:39:58Z [Term] id: FYPO:0002101 name: abolished 3'-5' DNA helicase activity def: "A molecular function phenotype in which an 3'-5' DNA helicase activity is absent." [PomBase:mah] synonym: "3'-5' DNA helicase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002100 ! abnormal 3'-5' DNA helicase activity created_by: midori creation_date: 2013-05-02T12:40:04Z [Term] id: FYPO:0002102 name: normal mitotic DNA damage checkpoint during cellular response to UV def: "A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage." [PomBase:mah] synonym: "normal DNA damage checkpoint during cellular response to UV during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint activation during cellular response to UV" EXACT [PomBase:al] synonym: "normal mitotic DNA damage checkpoint during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001705 ! normal mitotic DNA damage checkpoint is_a: FYPO:0004014 ! normal mitotic cell cycle regulation during cellular response to UV created_by: midori creation_date: 2013-05-02T13:15:58Z [Term] id: FYPO:0002103 name: inviable swollen mononucleate monoseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has one nucleus and one septum, and is swollen and inviable. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "inviable enlarged mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] synonym: "inviable large mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] synonym: "inviable mononucleate monoseptate vegetative cell with increased cell volume" EXACT [PomBase:mah] synonym: "inviable swollen mononucleate monoseptate cell" EXACT [PomBase:mah] synonym: "inviable swollen mononucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen mononucleate monoseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; swollen mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002303 ! inviable mononucleate monoseptate vegetative cell with anucleate compartment is_a: FYPO:0002414 ! inviable swollen vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology created_by: midori creation_date: 2013-05-07T12:15:31Z [Term] id: FYPO:0002104 name: viable vegetative cell with normal cell shape def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape and is viable." [PomBase:mah] synonym: "viable cell with normal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "viable vegetative cell with normal cell shape during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001125 ! normal vegetative cell shape is_a: FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2013-05-07T12:22:30Z [Term] id: FYPO:0002105 name: inviable vegetative cell with normal cell shape def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape but is inviable." [PomBase:mah] synonym: "inviable cell with normal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with normal cell shape during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; vegetative cell with normal cell shape" EXACT [PomBase:mah] is_a: FYPO:0001125 ! normal vegetative cell shape is_a: FYPO:0002199 ! inviable vegetative cell with normal cell morphology relationship: has_part FYPO:0001125 ! normal vegetative cell shape created_by: midori creation_date: 2013-05-07T12:27:52Z [Term] id: FYPO:0002106 name: viable stubby vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, but the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "stubby viable cell during vegetative growth" EXACT [PomBase:mah] synonym: "stubby viable vegetative cell" EXACT [PomBase:mah] synonym: "viable stubby vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable watermelon-shaped vegetative cell" EXACT [PMID:9108274, PomBase:vw] is_a: FYPO:0000024 ! stubby vegetative cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape is_a: FYPO:0006616 ! viable vegetative cell with increased cell diameter relationship: has_part FYPO:0000024 ! stubby vegetative cell created_by: midori creation_date: 2013-05-07T12:34:55Z [Term] id: FYPO:0002107 name: inviable stubby vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable stubby vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable watermelon-shaped vegetative cell" EXACT [PomBase:mah] synonym: "lethal; stubby vegetative cell" EXACT [PomBase:mah] synonym: "stubby inviable cell during vegetative growth" EXACT [PomBase:mah] synonym: "stubby inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000024 ! stubby vegetative cell is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000024 ! stubby vegetative cell created_by: midori creation_date: 2013-05-07T12:36:29Z [Term] id: FYPO:0002108 name: viable tapered cell def: "A cell morphology phenotype in which a cell is viable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable bottle-shaped cell" EXACT [PomBase:vw] synonym: "viable bottle/skittle cell" EXACT [PomBase:mah] synonym: "viable skittle-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0001119 ! tapered vegetative cell relationship: has_part FYPO:0000014 ! tapered cell relationship: has_part FYPO:0000124 ! viable cell created_by: midori creation_date: 2013-05-07T12:41:18Z [Term] id: FYPO:0002109 name: inviable tapered cell def: "A cell morphology phenotype in which a cell is inviable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable bottle-shaped cell" EXACT [PomBase:vw] synonym: "inviable bottle/skittle cell" EXACT [PomBase:mah] synonym: "lethal; tapered cell" EXACT [PomBase:mah] synonym: "skittle-inviable shaped cell" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell is_a: FYPO:0001119 ! tapered vegetative cell relationship: has_part FYPO:0000014 ! tapered cell relationship: has_part FYPO:0000049 ! inviable cell created_by: midori creation_date: 2013-05-07T12:41:24Z [Term] id: FYPO:0002110 name: viable tapered vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable bottle-shaped vegetative cell" EXACT [PomBase:vw] synonym: "viable bottle-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable bottle/skittle vegetative cell" EXACT [PomBase:mah] synonym: "viable skittle-shaped vegetative cell" EXACT [PomBase:mah] synonym: "viable tapered cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002108 ! viable tapered cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape created_by: midori creation_date: 2013-05-07T12:42:50Z [Term] id: FYPO:0002111 name: inviable tapered vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable bottle-shaped vegetative cell" EXACT [PomBase:vw] synonym: "inviable bottle-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable bottle/skittle vegetative cell" EXACT [PomBase:mah] synonym: "inviable skittle-shaped vegetative cell" EXACT [PomBase:mah] synonym: "inviable tapered cell during vegetative growth" EXACT [PomBase:mah] synonym: "lethal; tapered vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002109 ! inviable tapered cell is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape created_by: midori creation_date: 2013-05-07T12:43:02Z [Term] id: FYPO:0002112 name: viable curved vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved viable cell" EXACT [PomBase:mah] synonym: "viable curved cell" EXACT [PomBase:mah] synonym: "viable curved cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000016 ! curved vegetative cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000016 ! curved vegetative cell created_by: midori creation_date: 2013-05-07T12:50:59Z [Term] id: FYPO:0002113 name: inviable curved vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "curved inviable cell" EXACT [PomBase:mah] synonym: "inviable curved cell" EXACT [PomBase:mah] synonym: "inviable curved cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable curved vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; curved vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000016 ! curved vegetative cell is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000016 ! curved vegetative cell created_by: midori creation_date: 2013-05-07T12:51:07Z [Term] id: FYPO:0002114 name: transmembrane transporter activity phenotype def: "A phenotype that affects a transmembrane transporter activity." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast transporter activity phenotype" EXACT [PomBase:mah] is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2013-05-07T13:25:10Z [Term] id: FYPO:0002115 name: normal transmembrane transporter activity def: "A molecular function phenotype in which the observed rate of a specified transmembrane transporter activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0002114 ! transmembrane transporter activity phenotype created_by: midori creation_date: 2013-05-07T13:26:31Z [Term] id: FYPO:0002116 name: abnormal transmembrane transporter activity def: "A molecular function phenotype in which the observed rate of a specified transmembrane transporter activity is abnormal." [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0002114 ! transmembrane transporter activity phenotype created_by: midori creation_date: 2013-05-07T13:27:14Z [Term] id: FYPO:0002117 name: abolished transporter activity def: "A molecular function phenotype in which a specified transporter activity is absent." [PomBase:mah] synonym: "transporter activity abolished" EXACT [PomBase:mah] is_a: FYPO:0002116 ! abnormal transmembrane transporter activity created_by: midori creation_date: 2013-05-07T13:27:44Z [Term] id: FYPO:0002118 name: decreased transporter activity def: "A molecular function phenotype in which the observed rate of a specified transporter activity is decreased." [PomBase:mah] synonym: "reduced transporter activity" EXACT [PomBase:mah] is_a: FYPO:0002116 ! abnormal transmembrane transporter activity created_by: midori creation_date: 2013-05-07T13:28:05Z [Term] id: FYPO:0002119 name: increased transporter activity def: "A molecular function phenotype in which the observed rate of a specified transporter activity is increased." [PomBase:mah] is_a: FYPO:0002116 ! abnormal transmembrane transporter activity created_by: midori creation_date: 2013-05-07T13:28:21Z [Term] id: FYPO:0002120 name: normal sodium:hydrogen antiporter activity def: "A molecular function phenotype in which the observed rate of sodium:hydrogen antiporter activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0002115 ! normal transmembrane transporter activity created_by: midori creation_date: 2013-05-07T13:30:13Z [Term] id: FYPO:0002121 name: abnormal sodium:hydrogen antiporter activity def: "A molecular function phenotype in which the observed rate of sodium:hydrogen antiporter activity is abnormal." [PomBase:mah] is_a: FYPO:0002116 ! abnormal transmembrane transporter activity created_by: midori creation_date: 2013-05-07T13:39:14Z [Term] id: FYPO:0002122 name: decreased sodium:hydrogen antiporter activity def: "A molecular function phenotype in which the observed rate of sodium:hydrogen antiporter activity is decreased." [PomBase:mah] synonym: "reduced sodium:hydrogen antiporter activity" EXACT [PomBase:mah] is_a: FYPO:0002118 ! decreased transporter activity is_a: FYPO:0002121 ! abnormal sodium:hydrogen antiporter activity created_by: midori creation_date: 2013-05-07T13:39:50Z [Term] id: FYPO:0002123 name: pyruvylated galactose absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4,6-pyruvylated D-galactose (4,6-O-[(1R)-1-carboxyethylidene]-D-galactose) measured in a cell is too low to detect." [PomBase:mah] synonym: "4,6-O-[(1R)-1-carboxyethylidene]-D-galactose absent from cell" EXACT [CHEBI:61747] synonym: "4,6-pyruvylated D-galactose absent from cell" EXACT [CHEBI:61747] synonym: "PvGal absent from cell" EXACT [PMID:25195688] synonym: "pyruvylated galactose absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "pyruvylated galactose absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth created_by: midori creation_date: 2013-05-07T15:16:42Z [Term] id: FYPO:0002125 name: abnormal protein localization to plasma membrane during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the plasma membrane and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization in plasma membrane during vegetative growth" EXACT [GO:0072659] synonym: "abnormal protein localization to plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004838 ! abnormal protein localization to plasma membrane created_by: midori creation_date: 2013-05-07T16:29:31Z [Term] id: FYPO:0002126 name: abolished protein localization to plasma membrane during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization in plasma membrane during vegetative growth" EXACT [GO:0072659] synonym: "abolished protein localization to cell membrane during vegetative growth" EXACT [GO:0005886] synonym: "abolished protein localization to plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to plasma membrane abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002125 ! abnormal protein localization to plasma membrane during vegetative growth created_by: midori creation_date: 2013-05-07T16:32:01Z [Term] id: FYPO:0002127 name: increased protein localization to plasma membrane during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization in plasma membrane during vegetative growth" EXACT [GO:0072659] synonym: "increased protein localization to cell membrane during vegetative growth" EXACT [GO:0005886] synonym: "increased protein localization to plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002125 ! abnormal protein localization to plasma membrane during vegetative growth created_by: midori creation_date: 2013-05-07T16:32:58Z [Term] id: FYPO:0002128 name: abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to plasma membrane, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization in plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [GO:0072659] synonym: "abolished protein localization to cell membrane, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [GO:0005886] synonym: "abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to plasma membrane abolished, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0002126 ! abolished protein localization to plasma membrane during vegetative growth relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2013-05-07T16:35:01Z [Term] id: FYPO:0002129 name: increased protein phosphorylation during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to heat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to heat shock" NARROW [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-05-07T16:53:04Z [Term] id: FYPO:0002130 name: abolished protein phosphorylation during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to heat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to heat shock" NARROW [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-05-07T16:53:59Z [Term] id: FYPO:0002131 name: protein-RNA interaction phenotype def: "A phenotype that affects an interaction between a protein and RNA. One of the relevant gene product may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast protein-RNA interaction phenotype" EXACT [PomBase:mah] synonym: "fission yeast RNA binding phenotype" EXACT [PomBase:mah] synonym: "RNA binding phenotype" EXACT [PomBase:mah] synonym: "RNA-protein interaction phenotype" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-05-07T16:56:35Z [Term] id: FYPO:0002132 name: abnormal protein-RNA interaction def: "A molecular function phenotype in which an interaction between a protein and RNA is abnormal. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] comment: This term can be used for any interaction with RNA that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal RNA binding" EXACT [PomBase:mah] synonym: "abnormal RNA-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0002131 ! protein-RNA interaction phenotype created_by: midori creation_date: 2013-05-07T16:56:52Z [Term] id: FYPO:0002133 name: abolished protein-RNA interaction def: "A molecular function phenotype in which an interaction between a protein and RNA does not occur. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "abolished RNA binding" EXACT [PomBase:mah] synonym: "abolished RNA-protein interaction" EXACT [PomBase:mah] synonym: "RNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0002132 ! abnormal protein-RNA interaction created_by: midori creation_date: 2013-05-07T16:57:26Z [Term] id: FYPO:0002134 name: decreased protein-RNA interaction def: "A molecular function phenotype in which an interaction between a protein and RNA is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "decreased RNA binding" EXACT [PomBase:mah] synonym: "decreased RNA-protein interaction" EXACT [PomBase:mah] synonym: "reduced RNA binding" EXACT [PomBase:mah] is_a: FYPO:0002132 ! abnormal protein-RNA interaction created_by: midori creation_date: 2013-05-07T16:57:49Z [Term] id: FYPO:0002135 name: increased protein-RNA interaction def: "A molecular function phenotype in which an interaction between a protein and RNA is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "increased RNA binding" EXACT [PomBase:mah] synonym: "increased RNA-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0002132 ! abnormal protein-RNA interaction created_by: midori creation_date: 2013-05-07T16:58:03Z [Term] id: FYPO:0002136 name: abnormal RNA catabolic process during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process is abnormal." [GO:0006401, PomBase:mah] synonym: "abnormal RNA breakdown during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RNA catabolism during vegetative growth" EXACT [GO:0006401] synonym: "abnormal RNA degradation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0003551 ! abnormal RNA catabolic process created_by: midori creation_date: 2013-05-07T17:08:20Z [Term] id: FYPO:0002137 name: decreased RNA catabolic process during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process is decreased." [PomBase:mah] synonym: "decreased RNA breakdown during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA catabolism during vegetative growth" EXACT [GO:0006401] synonym: "decreased RNA degradation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA catabolic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002136 ! abnormal RNA catabolic process during vegetative growth is_a: FYPO:0003552 ! decreased RNA catabolic process relationship: has_output FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-05-07T17:09:04Z [Term] id: FYPO:0002138 name: increased RNA catabolic process during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process is increased." [PomBase:mah] synonym: "increased RNA breakdown during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA catabolism during vegetative growth" EXACT [GO:0006401] synonym: "increased RNA degradation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002136 ! abnormal RNA catabolic process during vegetative growth is_a: FYPO:0003553 ! increased RNA catabolic process relationship: has_output FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-05-07T17:09:43Z [Term] id: FYPO:0002139 name: obsolete abolished protein threonine phosphorylation at Thr-Pro site during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues N-terminal to proline residues (i.e. in Thr-Pro sequences) does not occur." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein threonine phosphorylation at Thr-Pro site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein threonine phosphorylation at threonine-proline site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein threonine phosphorylation at TP site during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002033 created_by: midori creation_date: 2013-05-08T15:37:59Z [Term] id: FYPO:0002140 name: increased cellular pigment accumulation during cellular response to caffeine def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased during a cellular response to caffeine." [PomBase:mah] comment: Note that normal cells do not accumulate detectable levels of any pigment; for this reason, FYPO does not include separate terms for 'increased' and 'abnormal' pigment accumulation. Also note that pigment accumulates in the vacuole. This term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "abnormal cellular pigment accumulation during cellular response to caffeine" EXACT [PomBase:mah] synonym: "altered colony color during cellular response to caffeine" RELATED [PomBase:al, PomBase:mah] synonym: "altered colony colour during cellular response to caffeine" RELATED [PomBase:al, PomBase:mah] synonym: "increased cellular pigment accumulation during cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular pigment accumulation during cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000741 ! increased cellular pigment accumulation created_by: midori creation_date: 2013-05-08T15:43:11Z [Term] id: FYPO:0002141 name: normal cell population growth at low temperature def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a low temperature." [PomBase:mah] synonym: "normal growth at low temperature" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth at low temperature" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-05-08T15:54:16Z [Term] id: FYPO:0002142 name: altered cellular reactive oxygen species level def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular reactive oxygen species level" EXACT [PomBase:mah] synonym: "abnormal cellular ROS accumulation" RELATED [PomBase:mah] synonym: "altered cellular ROS level" RELATED [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2013-05-08T16:16:09Z [Term] id: FYPO:0002143 name: decreased cellular reactive oxygen species level in stationary phase def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "decreased cellular reactive oxygen species accumulation in stationary phase" RELATED [PomBase:mah] synonym: "decreased cellular ROS accumulation in stationary phase" RELATED [PomBase:mah] synonym: "decreased cellular ROS level in stationary phase" EXACT [PomBase:mah] synonym: "decreased ROS accumulation in stationary phase" RELATED [PomBase:al] synonym: "reduced cellular reactive oxygen species level in stationary phase" EXACT [PomBase:mah] synonym: "reduced cellular ROS level in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0002142 ! altered cellular reactive oxygen species level created_by: midori creation_date: 2013-05-08T16:20:07Z [Term] id: FYPO:0002144 name: obsolete increased protein threonine phosphorylation at Thr-Pro site during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues N-terminal to proline residues (i.e. in Thr-Pro sequences) occurs to a greater extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased protein threonine phosphorylation at Thr-Pro site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein threonine phosphorylation at threonine-proline site during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein threonine phosphorylation at TP site during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001038 created_by: midori creation_date: 2013-05-09T10:13:48Z [Term] id: FYPO:0002145 name: normal protein localization to nucleus during cellular response to DEM def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to diethyl maleate (DEM), a compound which can induce oxidative stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during cellular response to DEM" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to DEM during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to DEM during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to diethyl maleate" EXACT [PomBase:mah] is_a: FYPO:0001789 ! normal protein localization to nucleus during cellular response to oxidative stress created_by: midori creation_date: 2013-05-09T10:17:24Z [Term] id: FYPO:0002146 name: normal RNA level during cellular response to DEM def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to diethyl maleate (DEM) is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to DEM" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to DEM" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to DEM during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to DEM during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to diethyl maleate" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to DEM" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2013-05-09T10:27:14Z [Term] id: FYPO:0002147 name: obsolete inviable vegetative cell population after spore germination def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable. The population may be mixed with respect to other phenotypes (e.g. whether cell division occurs)." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "cell population inviable after spore germination" EXACT [PomBase:mah] synonym: "inviable germinated spore population" EXACT [PomBase:mah] synonym: "population of inviable germinated spores" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-05-10T13:02:05Z [Term] id: FYPO:0002148 name: inviable after spore germination, multiple cell divisions, abnormal morphology def: "A phenotype in which a spore germinates to produce a cell of abnormal morphology (i.e. size, shape, or structure) that undergoes two or more rounds of cell division, and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, abnormal morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, abnormal morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, abnormal morphology" EXACT [PomBase:mah] is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2013-05-10T14:11:52Z [Term] id: FYPO:0002149 name: obsolete inviable elongated vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable and elongated in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-05-10T14:18:17Z [Term] id: FYPO:0002150 name: inviable spore population def: "A cell population phenotype in which none of the cells in a population of spores are viable. Inviable spores do not germinate." [PomBase:mah] comment: Use this term only if no germination is observed in the entire population of mutant spores. An example of when this term is applicable is where a gene deletion in a diploid causes all null-mutant spores to fail to germinate, but the same gene deletion in vegetative cells is viable. To describe a mixed spore population in which some spores germinate and others do not, use the cell phenotype 'inviable spore' (FYPO:0002151; also consider related terms) with an extension to indicate penetrance. synonym: "essential in spore population" RELATED [PomBase:mah] synonym: "inviable population of spores" EXACT [PomBase:vw] synonym: "lethal in spore population" EXACT [PomBase:mah] is_a: FYPO:0002059 ! inviable cell population created_by: midori creation_date: 2013-05-10T14:20:09Z [Term] id: FYPO:0002151 name: inviable spore alt_id: FYPO:0000306 def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive. An inviable spore does not germinate." [PomBase:mah] synonym: "abolished spore germination" RELATED [PomBase:mah] synonym: "decreased spore viability" RELATED [PomBase:mah] synonym: "lethal in spore" EXACT [PomBase:mah] synonym: "spore germination abolished" RELATED [PomBase:mah] is_a: FYPO:0000049 ! inviable cell created_by: midori creation_date: 2013-05-10T14:22:34Z [Term] id: FYPO:0002152 name: obsolete inviable small vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable and have a lower volume than normal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-05-10T14:25:01Z [Term] id: FYPO:0002153 name: obsolete viable small vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable but have a lower volume than normal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "wee population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-05-10T14:26:01Z [Term] id: FYPO:0002155 name: normal telomere structure during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region." [PomBase:mah] synonym: "normal chromosome structure at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromosome structure at telomeric region during vegetative growth" EXACT [GO:0000781, PomBase:mah] synonym: "normal telomere structure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal telomeric region structure during vegetative growth" EXACT [GO:0000781, PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth is_a: FYPO:0006514 ! normal telomere structure created_by: midori creation_date: 2013-05-10T15:34:01Z [Term] id: FYPO:0002156 name: binucleate monoseptate cell, with angled septum def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum, and in which the septum is located between the two nuclei but is not perpendicular to the long axis of the cell." [PomBase:mah] comment: Note that a cell that has the phenotype 'angled actomyosin contractile ring' (FYPO:0002027) will usually also subsequently display this phenotype. When using this term, also consider annotating to a cell cycle arrest term, such as 'abnormal cell cycle arrest in mitotic telophase' (FYPO:0000622); 'abnormal cell cycle arrest in mitotic anaphase' (FYPO:0000619) may be applicable if the assay detects DNA masses. Binucleate cells often arise as a result of cell cycle arrest. synonym: "binucleate monoseptate cell, with angled septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "binucleate monoseptate cell, with angled septum, during vegetative growth" EXACT [PomBase:mah] synonym: "binucleate monoseptate cell, with septum not orthogonal to long axis" RELATED [PomBase:mah] is_a: FYPO:0001222 ! binucleate vegetative cell is_a: FYPO:0001390 ! misoriented septum during vegetative growth created_by: midori creation_date: 2013-05-10T15:43:47Z [Term] id: FYPO:0002157 name: normal 1,3-beta-D-glucan synthase activity def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2013-05-10T16:01:38Z [Term] id: FYPO:0002158 name: abolished response to mitotic G2/M transition DNA damage checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to G2/M transition DNA damage checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal." [PomBase:mah] comment: May indicate that a cell cycle checkpoint is not activated under conditions that normally trigger checkpoint signaling and subsequent cell cycle arrest. synonym: "abolished mitotic G2/M transition DNA damage checkpoint arrest" RELATED [PomBase:mah] synonym: "abolished response to mitotic G2 DNA damage checkpoint signaling" EXACT [GO:0072435] synonym: "cell cycle arrest resulting from mitotic G2/M transition DNA damage activation abolished" EXACT [GO:0072435] synonym: "response to mitotic G2/M transition DNA damage checkpoint signaling abolished" EXACT [PomBase:mah] is_a: FYPO:0002519 ! abolished response to mitotic G2/M transition checkpoint signaling created_by: midori creation_date: 2013-10-29T16:27:16Z [Term] id: FYPO:0002159 name: decreased 1,3-beta-D-glucan synthase activity def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is decreased." [PomBase:mah] synonym: "reduced 1,3-beta-D-glucan synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001967 ! abnormal 1,3-beta-D-glucan synthase activity created_by: midori creation_date: 2013-05-10T16:04:01Z [Term] id: FYPO:0002160 name: normal growth on cilofungin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cilofungin." [PomBase:mah] synonym: "normal cell population growth in presence of cilofungin" EXACT [PomBase:mah] synonym: "normal cell population growth on cilofungin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cilofungin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cilofungin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-05-10T16:10:52Z [Term] id: FYPO:0002161 name: normal growth on Calcofluor White def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Calcofluor White." [PomBase:mah] synonym: "normal cell population growth in presence of Calcofluor White" EXACT [PomBase:mah] synonym: "normal cell population growth on Calcofluor White" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to Calcofluor White" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on Calcofluor White" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-05-10T16:11:44Z [Term] id: FYPO:0002162 name: resistance to cilofungin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cilofungin than normal." [PomBase:mah] synonym: "resistance to cilofungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cilofungin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to cilofungin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-05-10T16:15:33Z [Term] id: FYPO:0002163 name: decreased cell wall thickness during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thinner than normal." [PomBase:mah] synonym: "decreased cell wall thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced cell wall thickness during vegetative growth" EXACT [PomBase:mah] synonym: "thin cell wall during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0006745 ! abnormal cell wall thickness during vegetative growth created_by: midori creation_date: 2013-05-10T16:26:35Z [Term] id: FYPO:0002164 name: mislocalized, curved actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring in an abnormal location, and the ring has a curved, or C-shaped, profile. The normal location is at the midpoint of, and perpendicular to, the long axis of the cell." [PomBase:mah] comment: Note that the location of the contractile ring is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. synonym: "actomyosin contractile ring displaced from midpoint and bent" RELATED [PomBase:vw] synonym: "actomyosin contractile ring displaced from midpoint and curved" EXACT [PomBase:vw] synonym: "contractile ring displaced from cell centre and curved" EXACT [PomBase:vw] synonym: "mislocalised, curved actomyosin contractile ring" EXACT [PomBase:mah] synonym: "mislocalized, curved actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized, curved actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized, curved cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "mislocalized, curved mitotic contractile ring" EXACT [PomBase:vw] is_a: FYPO:0002026 ! actomyosin contractile ring displaced from midpoint created_by: midori creation_date: 2013-05-10T16:32:44Z [Term] id: FYPO:0002165 name: abnormal polynucleotide 3'-phosphatase activity def: "A molecular function phenotype in which the observed rate of polynucleotide 3'-phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-05-14T13:31:29Z [Term] id: FYPO:0002166 name: abolished polynucleotide 3'-phosphatase activity def: "A molecular function phenotype in which polynucleotide 3'-phosphatase activity is absent." [PomBase:mah] synonym: "polynucleotide 3'-phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002165 ! abnormal polynucleotide 3'-phosphatase activity created_by: midori creation_date: 2013-05-14T13:31:35Z [Term] id: FYPO:0002167 name: sensitive to ethyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethyl methanesulfonate. Cells stop growing (and may die) at a concentration of ethyl methanesulfonate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to ethyl methanesulfonate" EXACT [PomBase:mah] synonym: "sensitive to EMS" EXACT [PomBase:mah] synonym: "sensitive to ethyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ethyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ethyl methanesulphonate" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2013-05-14T13:34:52Z [Term] id: FYPO:0002168 name: normal growth on ethyl methanesulfonate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethyl methanesulfonate." [PomBase:mah] synonym: "normal cell population growth in presence of ethyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal cell population growth on EMS" EXACT [PomBase:mah] synonym: "normal cell population growth on ethyl methanesulfonate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to ethyl methanesulfonate" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on ethyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on ethyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-05-14T13:37:06Z [Term] id: FYPO:0002169 name: normal growth during cellular response to gamma radiation def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to gamma radiation." [PomBase:mah] synonym: "normal cell population growth during cellular response to gamma irradiation" EXACT [PomBase:al] synonym: "normal cell population growth during cellular response to gamma radiation" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth in response to gamma irradiation" RELATED [PomBase:al] synonym: "normal cellular response to gamma radiation" RELATED [PomBase:mah] synonym: "normal sensitivity to gamma radiation" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to gamma radiation" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-05-14T13:52:38Z [Term] id: FYPO:0002170 name: inviable after spore germination, multiple cell divisions, branched, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated), and undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated and branched cell" EXACT [PomBase:al] synonym: "inviable following spore germination, multiple cell divisions, branched, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, branched, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, branched, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0002262 ! inviable after spore germination, multiple cell divisions, elongated cell created_by: midori creation_date: 2013-05-14T13:55:18Z [Term] id: FYPO:0002171 name: obsolete viable cell at low temperature def: "OBSOLETE. A viability phenotype observed in the vegetative growth phase of the life cycle in which a cell is able to survive at a low temperature." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the cell viability term with conditions specified. synonym: "cell viable at low temperature" EXACT [PomBase:mah] synonym: "viable cell at low temperature during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable cell at low temperature during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-05-14T14:01:04Z [Term] id: FYPO:0002172 name: increased level of nitrogen starvation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during nitrogen starvation measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of cellular response to nitrogen starvation gene mRNA during vegetative growth" EXACT [PomBase:al] synonym: "increased level of nitrogen depletion gene mRNA during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of nitrogen deprivation gene mRNA during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of nitrogen starvation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of nitrogen starvation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of nitrogen starvation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased nitrogen starvation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-05-14T15:48:52Z [Term] id: FYPO:0002173 name: increased level of meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during the meiotic cell cycle measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of meiotic cell cycle gene mRNA during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of meiotic gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of meiotic nuclear division gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased meiotic gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "untimely expression of gametogenic genes during mitotic growth" EXACT [PMID:33574613, PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-05-14T15:52:47Z [Term] id: FYPO:0002174 name: decreased degradation of DSR-containing RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process that specifically degrades DSR-containing RNA molecules is decreased. A DSR (determinant of selective removal) is a region that is often found near the 3' end of meiosis-specific transcripts, usually contains one or more copies of the motif U(U/C/G)AAAC, and targets RNAs for degradation in vegetatively growing cells." [PMID:22046364, PMID:22645662, PomBase:mah] synonym: "decreased catabolism of DSR-containing RNA" EXACT [PomBase:mah] synonym: "decreased degradation of DSR-containing RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased degradation of DSR-containing RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA catabolic process, DSR-containing RNA" EXACT [GO:0006401, PomBase:mah] synonym: "reduced degradation of DSR-containing RNA" EXACT [PomBase:mah] is_a: FYPO:0002137 ! decreased RNA catabolic process during vegetative growth created_by: midori creation_date: 2013-05-14T16:03:57Z [Term] id: FYPO:0002176 name: viable vegetative cell with normal cell size def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has normal volume and dimensions and is viable." [PomBase:mah] synonym: "viable cell with normal cell size during vegetative growth" EXACT [PomBase:mah] synonym: "viable vegetative cell with normal cell length" NARROW [PomBase:mah] synonym: "viable vegetative cell with normal cell size during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0001124 ! normal vegetative cell size is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth relationship: has_part FYPO:0001124 ! normal vegetative cell size created_by: midori creation_date: 2013-06-04T12:51:12Z [Term] id: FYPO:0002177 name: viable vegetative cell with normal cell morphology def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has normal volume, dimensions and shape, and is viable." [PomBase:mah] synonym: "viable vegetative cell with normal cell shape and size" EXACT [PomBase:vw] synonym: "viable vegetative cell with normal morphology" EXACT [PomBase:vw] is_a: FYPO:0001315 ! normal vegetative cell morphology is_a: FYPO:0001491 ! viable vegetative cell relationship: has_part FYPO:0001315 ! normal vegetative cell morphology created_by: midori creation_date: 2013-06-04T12:52:23Z [Term] id: FYPO:0002178 name: obsolete viable mixed population including long cells def: "OBSOLETE. A mixed population phenotype in which cells in the population are viable, and some cells are longer than normal." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "long low penetrance" RELATED [PomBase:jh, PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-06-04T14:10:37Z [Term] id: FYPO:0002179 name: obsolete inviable mixed population, vegetative cells with abnormal morphology, including long cells def: "OBSOLETE. A mixed population phenotype in which a microcolony forms, all cells in the population are inviable and have abnormal morphology (i.e. size, shape, or structure), some cells may divide, and some cells are longer than normal." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable microcolony of vegetative cells with abnormal morphology, including long cells" EXACT [PomBase:mah, PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-06-04T15:30:24Z [Term] id: FYPO:0002180 name: obsolete viable mixed vegetative cell population including cell with normal morphology and long cells def: "OBSOLETE. A mixed population phenotype in which cells in the population are viable, some cells are longer than normal, and the rest of the cells are of normal morphology (i.e. size, shape, and structure)." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "long low penetrance" RELATED [PomBase:jh, PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-06-04T15:36:23Z [Term] id: FYPO:0002181 name: obsolete inviable mixed population including germinated spores and spheroid cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of germinated spores and spheroid vegetative cells. The spheroid cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including germinated spores and rounded cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T15:53:26Z [Term] id: FYPO:0002182 name: obsolete inviable mixed population including spores, germinated spores and spheroid cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and spheroid vegetative cells. The spheroid cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including spores, germinated spores and rounded cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T16:11:59Z [Term] id: FYPO:0002183 name: obsolete inviable mixed population including spores, germinated spores and cells with normal morphology def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and cells with normal morphology (i.e. size, shape, and structure). The cells with normal morphology arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-06-04T16:13:03Z [Term] id: FYPO:0002184 name: obsolete inviable mixed population including spores, germinated spores and tapered cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and tapered vegetative cells. The tapered cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including spores, germinated spores and bottle/skittle cells" EXACT [PomBase:mah] synonym: "inviable mixed population including spores, germinated spores and skittle-shaped cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T16:20:17Z [Term] id: FYPO:0002185 name: obsolete inviable mixed population including germinated spores and tapered cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of germinated spores and tapered vegetative cells. The tapered cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including germinated spores and bottle/skittle cells" RELATED [PomBase:mah] synonym: "inviable mixed population including germinated spores and skittle-shaped cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T16:22:21Z [Term] id: FYPO:0002186 name: obsolete inviable microcolony, small cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a lower volume than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, small vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T16:42:49Z [Term] id: FYPO:0002187 name: inviable normal volume spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, and has a normal volume." [PomBase:mah] synonym: "inviable normal volume rounded vegetative cell" EXACT [PomBase:mah] synonym: "inviable normal volume spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable normal volume spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; normal volume spheroid vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000946 ! normal volume spheroid vegetative cell is_a: FYPO:0001511 ! inviable vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0002482 ! inviable spheroid vegetative cell created_by: midori creation_date: 2013-06-04T17:02:22Z [Term] id: FYPO:0002188 name: obsolete inviable microcolony, normal volume spheroid cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a normal volume and spheroid shape. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, normal volume rounded cells" EXACT [PomBase:mah] synonym: "inviable microcolony, normal volume spheroid vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T17:03:55Z [Term] id: FYPO:0002189 name: viable normal volume spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, is shaped in the form of a spheroid, and has a normal volume." [PomBase:mah] synonym: "viable normal volume rounded vegetative cell" EXACT [PomBase:mah] synonym: "viable normal volume spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable normal volume spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000946 ! normal volume spheroid vegetative cell is_a: FYPO:0001510 ! viable vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0002380 ! viable spheroid vegetative cell created_by: midori creation_date: 2013-06-04T17:06:17Z [Term] id: FYPO:0002190 name: inviable swollen spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "inviable enlarged spheroid vegetative cell" RELATED [PomBase:mah] synonym: "inviable enlarged volume spheroid vegetative cell" EXACT [PomBase:mah] synonym: "inviable large spheroid vegetative cell" RELATED [PomBase:vw] synonym: "inviable swollen rounded vegetative cell" EXACT [PomBase:mah] synonym: "inviable swollen spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable, increased spheroid vegetative cell size" RELATED [PomBase:vw] synonym: "inviable, increased spheroid vegetative cell volume" EXACT [PomBase:mah] synonym: "lethal; swollen spheroid vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000945 ! swollen spheroid vegetative cell is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape is_a: FYPO:0002482 ! inviable spheroid vegetative cell created_by: midori creation_date: 2013-06-04T17:07:57Z [Term] id: FYPO:0002191 name: inviable swollen septated spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, has one or more septa, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "inviable enlarged septated spheroid vegetative cell" RELATED [PomBase:mah] synonym: "inviable enlarged volume septated spheroid vegetative cell" EXACT [PomBase:mah] synonym: "inviable septated large spheroid vegetative cell" RELATED [PomBase:vw] synonym: "inviable swollen septated rounded vegetative cell" EXACT [PomBase:mah] synonym: "inviable swollen septated spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen septated spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable, septated, increased spheroid vegetative cell size" RELATED [PomBase:vw] synonym: "inviable, septated, increased spheroid vegetative cell volume" EXACT [PomBase:mah] synonym: "lethal; swollen septated spheroid vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002190 ! inviable swollen spheroid vegetative cell is_a: FYPO:0002240 ! swollen septated spheroid vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology created_by: midori creation_date: 2013-06-04T17:09:31Z [Term] id: FYPO:0002192 name: obsolete inviable microcolony, normal volume septated spheroid cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a normal volume and spheroid shape, and contain one or more septa each. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, normal volume septated rounded cells" EXACT [PomBase:mah] synonym: "inviable microcolony, normal volume septated spheroid vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T17:27:04Z [Term] id: FYPO:0002193 name: inviable normal volume septated spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, contains one or more septa, is shaped in the form of a spheroid, and has a normal volume." [PomBase:mah] synonym: "inviable normal volume septated rounded vegetative cell" RELATED [PomBase:mah] synonym: "inviable normal volume septated spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable normal volume septated spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; normal volume septated spheroid vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000926 ! normal volume vegetative cell is_a: FYPO:0001511 ! inviable vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0001955 ! spheroid cell is_a: FYPO:0002342 ! septated vegetative cell relationship: has_part FYPO:0000926 ! normal volume vegetative cell relationship: has_part FYPO:0001955 ! spheroid cell relationship: has_part FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2013-06-04T17:28:33Z [Term] id: FYPO:0002194 name: obsolete inviable microcolony, swollen septated spheroid cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a larger volume than normal and spheroid shape, and contain one or more septa each. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, enlarged septated spheroid vegetative cells" RELATED [PomBase:mah] synonym: "inviable microcolony, septated large spheroid vegetative cells" RELATED [PomBase:vw] synonym: "inviable microcolony, septated, spheroid vegetative cells with increased cell size" RELATED [PomBase:vw] synonym: "inviable microcolony, septated, spheroid vegetative cells with increased cell volume" EXACT [PomBase:mah] synonym: "inviable microcolony, swollen septated rounded cells" EXACT [PomBase:mah] synonym: "inviable microcolony, swollen septated spheroid vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-04T17:31:20Z [Term] id: FYPO:0002195 name: obsolete normal morphology viable vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable and have normal morphology (i.e. size, shape, and structure) in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "viable vegetative cell population with normal cell morphology" EXACT [PomBase:mah] synonym: "viable vegetative cell population with normal cell shape and size" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-05T10:45:58Z [Term] id: FYPO:0002196 name: abnormal vegetative cell shape def: "A cell phenotype in which cell shape is altered in the vegetative growth phase of the life cycle." [PomBase:mah] comment: If possible, please consider using a more specific term to annotate each phenotype. synonym: "abnormal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vegetative cell shape during mitotic cell cycle" RELATED [PomBase:mah] synonym: "misshapen vegetative cell" RELATED [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2013-06-05T11:05:19Z [Term] id: FYPO:0002197 name: viable vegetative cell with abnormal cell shape def: "A cell phenotype in which a cell is viable, and cell shape is altered in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable lumpy cell" RELATED [PomBase:vw] synonym: "viable vegetative cell with abnormal cell shape during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable, abnormal cell shape during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001491 ! viable vegetative cell is_a: FYPO:0002196 ! abnormal vegetative cell shape relationship: has_part FYPO:0001126 ! abnormal cell shape relationship: has_part FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2013-06-05T11:09:19Z [Term] id: FYPO:0002198 name: obsolete viable vegetative cell population with abnormal cell shape def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable but have abnormal cell shape, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "viable, abnormally shaped vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-05T11:33:07Z [Term] id: FYPO:0002199 name: inviable vegetative cell with normal cell morphology def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal morphology (i.e. size, shape, and structure) but is inviable." [PomBase:mah] synonym: "inviable cell with normal cell morphology during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with normal cell morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable vegetative cell with normal cell shape and size" EXACT [PomBase:vw] synonym: "lethal; vegetative cell with normal cell morphology" EXACT [PomBase:mah] is_a: FYPO:0001315 ! normal vegetative cell morphology is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0001315 ! normal vegetative cell morphology created_by: midori creation_date: 2013-06-05T11:37:33Z [Term] id: FYPO:0002200 name: inviable stubby septated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable and has one or more septa, and the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable stubby septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable stubby septated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable watermelon-shaped septated vegetative cell" EXACT [PomBase:mah] synonym: "lethal; stubby septated vegetative cell" EXACT [PomBase:mah] synonym: "stubby septated inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002107 ! inviable stubby vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology created_by: midori creation_date: 2013-06-05T13:23:12Z [Term] id: FYPO:0002201 name: obsolete viable stubby vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable but the cell diameter is larger than normal and the cell length is shorter than normal, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "stubby viable vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-05T13:25:46Z [Term] id: FYPO:0002202 name: obsolete inviable stubby vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable and the cell diameter is larger than normal and the cell length is shorter than normal, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "stubby inviable vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-06-05T13:27:13Z [Term] id: FYPO:0002203 name: obsolete inviable microcolony, stubby cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells in which the cell diameter is larger than normal and the cell length is shorter than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, stubby vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-05T13:34:24Z [Term] id: FYPO:0002204 name: obsolete inviable microcolony, stubby septated cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that each contain one or more septa, and in which the cell diameter is larger than normal and the cell length is shorter than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, stubby septated vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-05T13:36:02Z [Term] id: FYPO:0002206 name: obsolete inviable swollen spore population def: "OBSOLETE. A cell population phenotype in which none of the cells in a population of spores are viable, and all have a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. Inviable spores do not germinate." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable enlarged spore population" RELATED [PomBase:mah] synonym: "inviable large spore population" RELATED [PomBase:vw] synonym: "inviable population of swollen spores" EXACT [PomBase:vw] synonym: "inviable spore population with increased cell size" RELATED [PomBase:vw] synonym: "inviable spore population with increased cell volume" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002150 created_by: midori creation_date: 2013-06-05T13:51:00Z [Term] id: FYPO:0002207 name: inviable swollen spore alt_id: FYPO:0000308 def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. An inviable spore does not germinate." [PomBase:mah] synonym: "inviable enlarged spore" RELATED [PomBase:mah] synonym: "inviable large spore" RELATED [PomBase:vw] synonym: "inviable spore with increased spore size" RELATED [PomBase:vw] synonym: "inviable spore with increased spore volume" EXACT [PomBase:mah] synonym: "lethal; swollen spore" EXACT [PomBase:mah] synonym: "spore germination abolished, enlarged spore" RELATED [PomBase:mah] synonym: "spore germination abolished, increased spore size" RELATED [PomBase:vw] synonym: "spore germination abolished, increased spore volume" RELATED [PomBase:mah] synonym: "spore germination abolished, large spore" RELATED [PomBase:vw] synonym: "spore germination abolished, swollen spore" RELATED [PomBase:mah] is_a: FYPO:0000309 ! inviable spore with abnormal morphology is_a: FYPO:0000347 ! swollen spore created_by: midori creation_date: 2013-06-05T13:52:59Z [Term] id: FYPO:0002208 name: inviable swollen spore with abnormal shape alt_id: FYPO:0002205 def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a larger volume than normal and an abnormal shape. An inviable spore does not germinate." [PomBase:mah] synonym: "inviable enlarged spore with abnormal shape" RELATED [PomBase:mah] synonym: "inviable large spore with abnormal shape" RELATED [PomBase:vw] synonym: "inviable spore with increased size and abnormal shape" RELATED [PomBase:vw] synonym: "inviable spore with increased spore size and abnormal shape" RELATED [PomBase:vw] synonym: "inviable spore with increased spore volume and abnormal shape" EXACT [PomBase:mah] synonym: "inviable spore with increased volume and abnormal shape" EXACT [PomBase:mah] synonym: "inviable swollen abnormally shaped spore" EXACT [PomBase:mah] synonym: "inviable swollen misshapen spore" RELATED [PomBase:mah] synonym: "lethal; swollen spore with abnormal shape" EXACT [PomBase:mah] synonym: "spore germination abolished, enlarged spore with abnormal shape" RELATED [PomBase:mah] synonym: "spore germination abolished, large spore with abnormal shape" RELATED [PomBase:vw] synonym: "spore germination abolished, spore with abnormal shape and increased cell size" RELATED [PomBase:vw] synonym: "spore germination abolished, spore with abnormal shape and increased cell volume" EXACT [PomBase:mah] synonym: "spore germination abolished, swollen misshapen spores" RELATED [PomBase:mah] synonym: "spore germination abolished, swollen spore with abnormal shape" RELATED [PomBase:mah] is_a: FYPO:0002207 ! inviable swollen spore is_a: FYPO:0002427 ! inviable spore with abnormal shape created_by: midori creation_date: 2013-06-05T13:58:55Z [Term] id: FYPO:0002209 name: obsolete inviable swollen spore population with abnormal spore shape def: "OBSOLETE. A cell population phenotype in which none of the cells in a population of spores are viable, and all have a larger volume than normal and an abnormal shape. Inviable spores do not germinate." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable enlarged spore population with abnormal spore shape" RELATED [PomBase:mah] synonym: "inviable large spore population with abnormal spore shape" RELATED [PomBase:vw] synonym: "inviable population of swollen spores with abnormal shape" EXACT [PomBase:vw] synonym: "inviable spore population with increased cell size and abnormal spore shape" RELATED [PomBase:vw] synonym: "inviable spore population with increased cell volume and abnormal spore shape" EXACT [PomBase:mah] synonym: "inviable swollen spore population with abnormal shape" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002150 created_by: midori creation_date: 2013-06-05T13:59:40Z [Term] id: FYPO:0002210 name: obsolete inviable microcolony, tapered cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that taper at one end to a diameter smaller than the other. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, bottle/skittle cells" EXACT [PomBase:mah] synonym: "inviable microcolony, skittle-shaped cells" EXACT [PomBase:mah] synonym: "inviable microcolony, tapered vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-05T14:18:25Z [Term] id: FYPO:0002211 name: obsolete inviable vegetative cell population after spore germination, elongated germ tubes def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, and the germinated spores have elongated germ tubes. The population may be mixed with respect to other phenotypes (e.g. whether cell division occurs)." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "cell population inviable after spore germination, with elongated germ tubes" EXACT [PomBase:mah] synonym: "inviable germinated spore population, elongated germ tubes" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-06-05T14:44:53Z [Term] id: FYPO:0002212 name: inviable after spore germination, without cell division, with elongated, curved germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube that is curved along the long axis, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination, without cell division, elongated, curved cell" EXACT [PomBase:mah] synonym: "inviable following spore germination with elongated, curved germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with elongated, curved germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with elongated, curved germ tube" EXACT [PomBase:mah] is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube is_a: FYPO:0002411 ! inviable curved elongated vegetative cell created_by: midori creation_date: 2013-06-05T14:47:02Z [Term] id: FYPO:0002213 name: obsolete inviable vegetative cell population after spore germination, elongated curved germ tubes def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, and the germinated spores have elongated germ tubes that are curved along the long axis. The population may be mixed with respect to other phenotypes (e.g. whether cell division occurs)." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "cell population inviable after spore germination, with elongated, curved germ tubes" EXACT [PomBase:mah] synonym: "inviable germinated spore population, elongated curved germ tubes" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-06-05T14:48:45Z [Term] id: FYPO:0002214 name: obsolete inviable vegetative cell population after spore germination, abnormal germ tube morphology def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, and have germ tubes with abnormal morphology (i.e. size, shape, or structure)." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "cell population inviable after spore germination, abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore population, abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable population of undivided germinated spores with abnormal germ tube morphology" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-06-05T14:55:56Z [Term] id: FYPO:0002215 name: viable curved elongated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, is elongated, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved elongated viable cell" EXACT [PomBase:mah] synonym: "viable curved elongated cell" EXACT [PomBase:mah] synonym: "viable curved elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell is_a: FYPO:0002112 ! viable curved vegetative cell is_a: FYPO:0005103 ! curved elongated vegetative cell created_by: midori creation_date: 2013-06-05T15:02:02Z [Term] id: FYPO:0002216 name: obsolete viable curved vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable and are curved along the long axis in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "population of curved viable cells" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-05T15:06:28Z [Term] id: FYPO:0002217 name: obsolete viable curved elongated vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable, elongated, and curved along the long axis in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "population of curved viable long cells" EXACT [PomBase:vw] synonym: "viable curved long vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-05T15:07:23Z [Term] id: FYPO:0002218 name: obsolete inviable vegetative cell population after spore germination, normal unseptated germ tube morphology def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, and have germ tubes with normal morphology (i.e. size, shape, and structure) that do not septate." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable germinated spore population, normal unseptated germ tube morphology" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-06-05T15:16:34Z [Term] id: FYPO:0002219 name: normal chromosome disjunction at meiosis I def: "A cellular process phenotype in which homologous chromosome segregation, or disjunction, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal chromosome disjunction at first meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal homologous chromosome segregation" EXACT [GO:0045143] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2013-06-05T16:23:45Z [Term] id: FYPO:0002220 name: increased duration of meiotic cell cycle phase def: "A cellular process phenotype in which the duration of one or more meiotic cell cycle phases is longer than normal." [PomBase:mah] synonym: "prolonged meiotic cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0000408 ! increased duration of cell cycle phase is_a: FYPO:0002738 ! abnormal meiotic cell cycle phase created_by: midori creation_date: 2013-06-05T16:26:25Z [Term] id: FYPO:0002221 name: increased duration of meiotic anaphase II def: "A cellular process phenotype in which the duration of progression through the anaphase of meiosis II is longer than normal." [PomBase:mah] synonym: "delayed meiotic anaphase II progression" RELATED [PomBase:mah] synonym: "increased duration of meiotic anaphase II progression" EXACT [PomBase:mah] synonym: "prolonged meiotic anaphase II" EXACT [PomBase:mah] is_a: FYPO:0002220 ! increased duration of meiotic cell cycle phase created_by: midori creation_date: 2013-06-05T16:27:42Z [Term] id: FYPO:0002222 name: long meiosis II spindle def: "A spindle phenotype in which the meiotic spindle is longer than normal during meiosis II." [PomBase:mah] comment: In extreme examples of this phenotype, the two elongating spindles may meet in the middle of the cell. synonym: "elongated meiosis II spindle" EXACT [PomBase:mah] synonym: "long spindle during meiosis II" EXACT [PomBase:mah] synonym: "long spindle during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "meiosis II spindle overextension" EXACT [PMID:29259000] is_a: FYPO:0000736 ! long meiotic spindle created_by: midori creation_date: 2013-06-05T16:35:26Z [Term] id: FYPO:0002223 name: abnormal cell cycle arrest in meiosis II def: "A cellular process phenotype in which progression through the meiotic cell cycle is arrested in meiosis II. Meiosis II is the second phase of meiosis, in which cells divide and separate the two chromatids in each chromosome." [GO:0007135, PomBase:mah] synonym: "abnormal cell cycle arrest in second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002224 ! abnormally arrested meiotic cell cycle created_by: midori creation_date: 2013-06-05T16:40:26Z [Term] id: FYPO:0002224 name: abnormally arrested meiotic cell cycle def: "A cellular process phenotype in which progression through the meiotic cell cycle is arrested under conditions where arrest does not normally occur." [PomBase:mah] is_a: FYPO:0000052 ! abnormal meiotic cell cycle is_a: FYPO:0000407 ! abnormally arrested cell cycle progression created_by: midori creation_date: 2013-06-05T16:41:00Z [Term] id: FYPO:0002225 name: obsolete inviable microcolony, elongated cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that are longer than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, elongated vegetative cells" EXACT [PomBase:mah] synonym: "inviable microcolony, long cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-05T16:45:49Z [Term] id: FYPO:0002226 name: obsolete inviable microcolony, abnormal cell shape, normal cell size def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells in which cell shape is altered and cell size remains normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. is_obsolete: true created_by: midori creation_date: 2013-06-05T16:52:35Z [Term] id: FYPO:0002227 name: increased cellular triglyceride level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular TAG level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular triacylglycerol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular triglyceride level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased triglyceride accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-05T17:03:18Z [Term] id: FYPO:0002228 name: normal cellular phosphatidylethanolamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular PE level" EXACT [PomBase:mah] synonym: "normal cellular phosphatidylethanolamine accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylethanolamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylethanolamine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-05T17:05:15Z [Term] id: FYPO:0002229 name: normal cellular ergosterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular ergosterol accumulation" RELATED [PomBase:mah] synonym: "normal cellular ergosterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular ergosterol level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-05T17:07:25Z [Term] id: FYPO:0002230 name: inviable swollen curved vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, has a larger volume than normal, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable curved cell with increased cell size" RELATED [PomBase:vw] synonym: "inviable curved cell with increased cell volume" EXACT [PomBase:mah] synonym: "inviable enlarged curved cell" RELATED [PomBase:mah] synonym: "inviable large curved cell" RELATED [PomBase:vw] synonym: "inviable swollen curved cell" EXACT [PomBase:mah] synonym: "inviable swollen curved cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen curved inviable cell" EXACT [PomBase:mah] synonym: "inviable swollen curved vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; swollen curved vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002113 ! inviable curved vegetative cell is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape created_by: midori creation_date: 2013-06-06T14:15:53Z [Term] id: FYPO:0002231 name: obsolete inviable microcolony, curved cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that are curved along the long axis. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, curved vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-06T14:18:49Z [Term] id: FYPO:0002232 name: obsolete inviable microcolony, swollen curved cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a larger volume than normal and are curved along the long axis. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, curved cells with increased cell size" RELATED [PomBase:vw] synonym: "inviable microcolony, curved cells with increased cell volume" EXACT [PomBase:mah] synonym: "inviable microcolony, enlarged curved cells" RELATED [PomBase:mah] synonym: "inviable microcolony, large curved cells" RELATED [PomBase:vw] synonym: "inviable microcolony, swollen curved vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-06T14:19:36Z [Term] id: FYPO:0002233 name: obsolete viable elongated vegetative cell population alt_id: FYPO:0002278 def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable but longer than normal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "population of viable long cells" EXACT [PomBase:vw] synonym: "viable long vegetative cell population" EXACT [PomBase:mah] synonym: "viable population of elongated vegetative cells" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-06T14:39:45Z [Term] id: FYPO:0002234 name: decreased cellular sterol ester level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more sterol esters measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular sterol ester level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular sterol ester level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of sterol ester in cell" EXACT [PomBase:mah] synonym: "decreased sterol ester accumulation" RELATED [PomBase:al] synonym: "reduced cellular sterol ester level" EXACT [PomBase:mah] synonym: "reduced level of sterol ester in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-06T15:18:37Z [Term] id: FYPO:0002235 name: increased cellular sterol ester level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more sterol esters measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular sterol ester level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular sterol ester level during vegetative growth" EXACT [PomBase:mah] synonym: "increased sterol ester accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-06T15:20:19Z [Term] id: FYPO:0002236 name: normal cellular sterol ester level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more sterol esters measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular sterol ester level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular sterol ester level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of sterol ester in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-06T15:21:32Z [Term] id: FYPO:0002237 name: sensitive to cerulenin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cerulenin. Cells stop growing (and may die) at a concentration of cerulenin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cerulenin" EXACT [PomBase:mah] synonym: "sensitive to cerulenin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cerulenin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-06-06T15:30:42Z [Term] id: FYPO:0002238 name: normal growth on cerulenin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cerulenin." [PomBase:mah] synonym: "normal cell population growth in presence of cerulenin" EXACT [PomBase:mah] synonym: "normal cell population growth on cerulenin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cerulenin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cerulenin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-06-06T15:32:04Z [Term] id: FYPO:0002239 name: shortened telomeres during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are shorter than normal." [PomBase:mah] synonym: "decreased telomere length during vegetative growth" EXACT [PomBase:mah] synonym: "reduced telomere length during vegetative growth" EXACT [PomBase:mah] synonym: "short telomeres during vegetative growth" EXACT [PomBase:mah] synonym: "shortened telomeres during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0006464 ! abnormal telomere length during vegetative growth created_by: midori creation_date: 2013-06-06T15:38:03Z [Term] id: FYPO:0002240 name: swollen septated spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, has one or more septa, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "enlarged septated spheroid vegetative cell" RELATED [PomBase:mah] synonym: "large septated spheroid vegetative cell" RELATED [PomBase:vw] synonym: "septated spheroid vegetative cell with increased cell size" RELATED [PomBase:vw] synonym: "septated spheroid vegetative cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen septated rounded vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000945 ! swollen spheroid vegetative cell is_a: FYPO:0005149 ! septated spheroid vegetative cell created_by: midori creation_date: 2013-06-06T16:24:19Z [Term] id: FYPO:0002241 name: normal volume septated spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, has one or more septa, and has a normal volume." [PomBase:mah] synonym: "normal volume septated rounded vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000946 ! normal volume spheroid vegetative cell is_a: FYPO:0005149 ! septated spheroid vegetative cell created_by: midori creation_date: 2013-06-06T16:26:51Z [Term] id: FYPO:0002242 name: inviable elongated tapered vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable elongated bottle-shaped vegetative cell" EXACT [PomBase:vw] synonym: "inviable elongated bottle-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated bottle/skittle vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated skittle-shaped vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated tapered cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable long tapered vegetative cell" EXACT [PomBase:mah] synonym: "lethal; elongated tapered vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002111 ! inviable tapered vegetative cell created_by: midori creation_date: 2013-06-06T16:28:17Z [Term] id: FYPO:0002243 name: increased acid phosphatase activity def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001044 ! abnormal acid phosphatase activity created_by: midori creation_date: 2013-06-06T16:31:24Z [Term] id: FYPO:0002244 name: abolished acid phosphatase activity def: "A molecular function phenotype in which acid phosphatase activity is absent." [PomBase:mah] synonym: "acid phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001044 ! abnormal acid phosphatase activity created_by: midori creation_date: 2013-06-06T16:36:41Z [Term] id: FYPO:0002245 name: abnormal monosaccharide binding def: "A molecular function phenotype in which occurrence of monosaccharide binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a monosaccharide that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-06-06T16:38:57Z [Term] id: FYPO:0002246 name: increased glucose binding def: "A molecular function phenotype in which occurrence of glucose binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds glucose more than wild type, or that a mutation in one gene increases glucose binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0002245 ! abnormal monosaccharide binding created_by: midori creation_date: 2013-06-06T16:42:50Z [Term] id: FYPO:0002247 name: decreased glucose binding def: "A molecular function phenotype in which occurrence of glucose binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds glucose less than wild type, or that a mutation in one gene decreases glucose binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "reduced glucose binding" EXACT [PomBase:mah] is_a: FYPO:0002245 ! abnormal monosaccharide binding created_by: midori creation_date: 2013-06-06T16:43:20Z [Term] id: FYPO:0002248 name: increased mannose binding def: "A molecular function phenotype in which occurrence of mannose binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds mannose more than wild type, or that a mutation in one gene increases mannose binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0002245 ! abnormal monosaccharide binding created_by: midori creation_date: 2013-06-06T16:43:54Z [Term] id: FYPO:0002249 name: decreased fructose binding def: "A molecular function phenotype in which occurrence of fructose binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds fructose less than wild type, or that a mutation in one gene decreases fructose binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "reduced fructose binding" EXACT [PomBase:mah] is_a: FYPO:0002245 ! abnormal monosaccharide binding created_by: midori creation_date: 2013-06-06T16:44:19Z [Term] id: FYPO:0002250 name: inviable curved vacuolated vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is curved along the long axis, and in which vacuoles are more visible (usually by microscopy) than normal." [PomBase:mah] synonym: "inviable curved vacuolated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable curved vacuolated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; curved vacuolated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002113 ! inviable curved vegetative cell relationship: has_part FYPO:0001581 ! vacuolated created_by: midori creation_date: 2013-06-07T15:30:03Z [Term] id: FYPO:0002251 name: inviable swollen elongated vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable and has a larger volume, and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "inviable elongated cell with increased cell volume" EXACT [PomBase:mah] synonym: "inviable enlarged elongated cell" RELATED [PomBase:mah] synonym: "inviable large elongated cell" RELATED [PomBase:vw] synonym: "inviable swollen elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; swollen elongated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0001429 ! swollen elongated cell is_a: FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2013-06-07T15:48:12Z [Term] id: FYPO:0002252 name: inviable swollen elongated mononucleate vegetative cell with normally localized septum def: "A cell phenotype in which a cell contains a single septum, has one nucleus, is elongated, and is inviable. The septum is in an abnormal location, and the nucleus is located in one compartment of the septated cell. The cell compartment containing the nucleus is swollen (i.e. has a larger diameter and volume than the other compartment)." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable elongated mononucleate vegetative cell with normally localized septum with increased cell volume" EXACT [PomBase:mah] synonym: "inviable enlarged elongated mononucleate vegetative cell with normally localized septum" RELATED [PomBase:mah] synonym: "inviable large elongated mononucleate vegetative cell with normally localized septum" RELATED [PomBase:vw] synonym: "inviable swollen elongated mononucleate vegetative cell with normally localised septum" EXACT [PomBase:mah] synonym: "inviable swollen elongated mononucleate vegetative cell with normally localized septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable swollen elongated mononucleate vegetative cell with normally positioned septum" EXACT [PomBase:mah] synonym: "lethal; swollen elongated mononucleate vegetative cell with normally localized septum" EXACT [PomBase:mah] synonym: "long swollen mononucleate cell with normally localized septum" EXACT [PomBase:vw] synonym: "swollen elongated mononucleate cell with normal septum position" NARROW [PomBase:mah] synonym: "swollen elongated mononucleate cell with normally localized septum near new end during vegetative growth" EXACT [PomBase:mah] synonym: "swollen elongated mononucleate cell with normally placed septum" EXACT [PomBase:vw] is_a: FYPO:0001917 ! inviable elongated mononucleate monoseptate vegetative cell is_a: FYPO:0002103 ! inviable swollen mononucleate monoseptate vegetative cell is_a: FYPO:0002253 ! normal septum location is_a: FYPO:0002845 ! inviable swollen elongated septated vegetative cell relationship: has_part FYPO:0002253 ! normal septum location created_by: midori creation_date: 2013-06-07T16:00:55Z [Term] id: FYPO:0002253 name: normal septum location def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in the normal location at the midpoint of the long axis of the cell." [PomBase:mah] synonym: "normal septum location during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septum location during vegetative growth" EXACT [PomBase:mah] synonym: "normal septum position" RELATED [PomBase:mah] synonym: "normally localized septum" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2013-06-07T16:05:04Z [Term] id: FYPO:0002254 name: abnormal telomere morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the telomere is abnormal." [PomBase:mah] comment: Note that an abnormal telomere organization process may, but does not necessarily, result in abnormal telomere morphology. synonym: "abnormal telomere morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0006508 ! abnormal telomere morphology relationship: RO:0002353 FYPO:0000122 ! abnormal telomere maintenance during vegetative growth created_by: midori creation_date: 2013-06-11T13:43:06Z [Term] id: FYPO:0002255 name: enlarged nucleus def: "A physical cellular phenotype in which the nucleus is larger than normal." [PomBase:mah] synonym: "enlarged nuclei" EXACT [PomBase:vw] is_a: FYPO:0002256 ! abnormal nuclear morphology created_by: midori creation_date: 2013-06-11T16:39:47Z [Term] id: FYPO:0002256 name: abnormal nuclear morphology def: "A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "deformed nucleus" EXACT [PomBase:vw] synonym: "nuclear morphology defects" EXACT [PomBase:mah] is_a: FYPO:0002403 ! abnormal nucleus created_by: midori creation_date: 2013-06-11T16:40:13Z [Term] id: FYPO:0002257 name: abnormal vacuolar morphology def: "A physical cellular phenotype in which the size, shape, or structure of the fungal-type vacuole is abnormal." [PomBase:mah] comment: Note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuole morphology" EXACT [PomBase:mah] synonym: "vacuolar morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2013-06-11T17:16:05Z [Term] id: FYPO:0002258 name: small vacuoles present in increased numbers def: "A cell phenotype in which a cell contains more, but smaller, vacuoles than normal." [PomBase:mah] synonym: "fragmented vacuoles" RELATED [PomBase:mah] synonym: "small vacuoles present in greater numbers" EXACT [PomBase:mah] synonym: "vacuole organization defects, fragmented vacuoles" RELATED [PomBase:mah] synonym: "vacuoles present in increased numbers, with decreased vacuole size" EXACT [PomBase:vw] is_a: FYPO:0002787 ! small vacuoles is_a: FYPO:0002790 ! vacuoles present in increased numbers created_by: midori creation_date: 2013-06-11T17:18:14Z [Term] id: FYPO:0002259 name: normal leucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-leucine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal L-leucine import" NARROW [PomBase:mah] synonym: "normal L-leucine import across plasma membrane" EXACT [GO:1903801] synonym: "normal leucine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal leucine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal leucine import into cell" EXACT [PomBase:al] synonym: "normal leucine uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2013-06-12T13:18:44Z [Term] id: FYPO:0002260 name: normal glutamate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-glutamate import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glutamate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal glutamate import during vegetative growth" EXACT [PomBase:mah] synonym: "normal glutamate import into cell" EXACT [PomBase:al] synonym: "normal glutamate uptake" EXACT [PomBase:mah] synonym: "normal glutamic acid import" EXACT [PomBase:mah] synonym: "normal L-glutamate import across plasma membrane" EXACT [GO:0098712] synonym: "normal L-glutamic acid import" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2013-06-12T13:21:09Z [Term] id: FYPO:0002261 name: abnormal N-glycan processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which N-glycan processing is abnormal." [PomBase:mah] synonym: "abnormal N-glycan catabolism" RELATED [GO:0006491] synonym: "abnormal N-glycan degradation" RELATED [GO:0006491] synonym: "abnormal N-glycan processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal N-glycan processing during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal N-linked glycoprotein maturation" EXACT [GO:0006491] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2013-06-12T13:53:52Z [Term] id: FYPO:0002262 name: inviable after spore germination, multiple cell divisions, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated, and undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002148 ! inviable after spore germination, multiple cell divisions, abnormal morphology created_by: midori creation_date: 2013-06-12T14:07:08Z [Term] id: FYPO:0002263 name: inviable after spore germination, without cell division, cell cycle arrest, elongated cell def: "A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then becomes elongated and undergoes cell cycle arrest, and eventually dies without completing cell division." [PomBase:mah] synonym: "inviable germinated spore, without cell division, cell cycle arrest, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, cell cycle arrest, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0001924 ! inviable after spore germination, without cell division, cell cycle arrest is_a: FYPO:0004603 ! inviable after spore germination, without cell division, elongated cell created_by: midori creation_date: 2013-06-12T14:30:44Z [Term] id: FYPO:0002264 name: increased concentration of polysaccharide in growth medium def: "A phenotype in which the concentration of one or more polysaccharides released into the growth medium by cells is higher than normal." [PomBase:mah] synonym: "increased concentration of polysaccharides in growth medium" EXACT [PomBase:al] synonym: "increased level of polysaccharide in growth medium" EXACT [PomBase:mah] synonym: "increased release of polysaccharide into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2013-06-12T14:46:22Z [Term] id: FYPO:0002265 name: decreased cell wall galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall galactomannan accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall galactomannan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell wall galactomannan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall galactomannan level" EXACT [PomBase:mah] is_a: FYPO:0001195 ! decreased galactomannan level is_a: FYPO:0002266 ! decreased cell wall polysaccharide level created_by: midori creation_date: 2013-06-12T14:48:20Z [Term] id: FYPO:0002266 name: decreased cell wall polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more polysaccharides measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall polysaccharide accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall polysaccharide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell wall polysaccharide level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall polysaccharide level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level during vegetative growth relationship: output_of FYPO:0000174 ! abnormal cell wall biogenesis created_by: midori creation_date: 2013-06-12T14:48:41Z [Term] id: FYPO:0002267 name: abnormal glutamate-ammonia ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is abnormal." [PomBase:mah] synonym: "abnormal glutamine synthetase activity" EXACT [GO:0004356, PomBase:mah] synonym: "abnormal glutamylhydroxamic synthetase activity" EXACT [GO:0004356] synonym: "abnormal GS activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-06-12T14:55:51Z [Term] id: FYPO:0002268 name: abolished glutamate-ammonia ligase activity def: "A molecular function phenotype in which glutamate-ammonia ligase activity is absent." [PomBase:mah] synonym: "abolished glutamine synthetase activity" EXACT [GO:0004356, PomBase:mah] synonym: "abolished glutamylhydroxamic synthetase activity" EXACT [GO:0004356] synonym: "abolished GS activity" EXACT [PMID:7851743, PomBase:al] synonym: "glutamate-ammonia ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002267 ! abnormal glutamate-ammonia ligase activity created_by: midori creation_date: 2013-06-12T14:56:05Z [Term] id: FYPO:0002269 name: decreased glutamate-ammonia ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is decreased." [PomBase:mah] synonym: "decreased glutamine synthetase activity" EXACT [GO:0004356, PomBase:mah] synonym: "decreased glutamylhydroxamic synthetase activity" EXACT [GO:0004356] synonym: "decreased GS activity" EXACT [PMID:7851743, PomBase:al] synonym: "reduced glutamate-ammonia ligase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002267 ! abnormal glutamate-ammonia ligase activity created_by: midori creation_date: 2013-06-12T14:56:15Z [Term] id: FYPO:0002270 name: increased glutamate-ammonia ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is increased." [PomBase:mah] synonym: "increased glutamine synthetase activity" EXACT [GO:0004356, PomBase:mah] synonym: "increased glutamylhydroxamic synthetase activity" EXACT [GO:0004356] synonym: "increased GS activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002267 ! abnormal glutamate-ammonia ligase activity created_by: midori creation_date: 2013-06-12T14:56:22Z [Term] id: FYPO:0002271 name: growth auxotrophic for glutamine def: "Auxotrophy in which a cell is unable to synthesize glutamine, and therefore requires glutamine in the medium for vegetative cell growth." [PomBase:mah] synonym: "glutamine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for glutamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for glutamine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2013-06-12T15:00:33Z [Term] id: FYPO:0002272 name: obsolete inviable microcolony, abnormal cell morphology def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have abnormal morphology (i.e. size, shape, or structure). Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, vegetative cells with abnormal morphology" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-12T15:37:46Z [Term] id: FYPO:0002273 name: inviable vegetative cell with abnormal cell morphology def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has abnormal morphology (i.e. size, shape, or structure) and is inviable." [PomBase:mah] synonym: "inviable cell with abnormal cell morphology during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with abnormal cell morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; vegetative cell with abnormal cell morphology" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology relationship: has_part FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2013-06-12T15:40:14Z [Term] id: FYPO:0002274 name: abnormal protein metabolic process def: "A cellular process phenotype in which a protein metabolic process is abnormal. A protein metabolic process is a series of chemical reactions and pathways involving a specific protein." [GO:0019538, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal cellular protein metabolic process" EXACT [PomBase:mah] synonym: "abnormal protein metabolism" EXACT [GO:0019538] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2013-06-12T15:51:09Z [Term] id: FYPO:0002275 name: abnormal protein degradation def: "A cellular process phenotype in which protein degradation is abnormal. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein breakdown" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolism" EXACT [GO:0030163, PomBase:mah] is_a: FYPO:0002274 ! abnormal protein metabolic process created_by: midori creation_date: 2013-06-12T15:53:25Z [Term] id: FYPO:0002276 name: increased protein degradation def: "A cellular process phenotype in which the occurrence of protein degradation is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein breakdown" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolism" EXACT [GO:0030163, PomBase:mah] is_a: FYPO:0002275 ! abnormal protein degradation relationship: has_output FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2013-06-12T15:56:44Z [Term] id: FYPO:0002277 name: increased protein degradation during nitrogen starvation def: "A cellular process phenotype in which the occurrence of protein degradation is increased when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein breakdown during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolic process during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolism during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein degradation during nitrogen depletion" EXACT [PomBase:vw] synonym: "increased protein degradation during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002276 ! increased protein degradation is_a: FYPO:0002796 ! abnormal protein degradation during nitrogen starvation relationship: has_output FYPO:0001283 ! decreased protein level during cellular response to nitrogen starvation created_by: midori creation_date: 2013-06-12T15:59:06Z [Term] id: FYPO:0002279 name: inviable after spore germination, single cell division, with elongated, curved germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube that is curved along the long axis, and undergoes a single round of cell division." [PomBase:mah] synonym: "inviable after spore germination, single cell division, elongated, curved cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, single cell division, with elongated, curved germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division, with elongated, curved germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division, with elongated, curved germ tube" EXACT [PomBase:mah] is_a: FYPO:0002409 ! inviable after spore germination, single cell division, with elongated germ tube is_a: FYPO:0002411 ! inviable curved elongated vegetative cell created_by: midori creation_date: 2013-06-12T16:14:09Z [Term] id: FYPO:0002280 name: inviable after spore germination, single cell division def: "A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division, and then dies." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable following spore germination, single cell division" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division" EXACT [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2013-06-12T16:15:22Z [Term] id: FYPO:0002281 name: inviable after spore germination with abnormal germ tube morphology def: "A phenotype in which a spore germinates to produce a germ tube with abnormal size, shape, or structure." [PomBase:mah] synonym: "inviable following spore germination with abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore with abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination with abnormal germ tube morphology" EXACT [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology created_by: midori creation_date: 2013-06-12T16:18:21Z [Term] id: FYPO:0002282 name: inviable curved septated vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is curved along the long axis, and has one or more septa." [PomBase:mah] synonym: "inviable curved septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable curved septated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; curved septated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002113 ! inviable curved vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology created_by: midori creation_date: 2013-06-12T16:30:43Z [Term] id: FYPO:0002283 name: obsolete abolished protein tyrosine phosphorylation during cellular response to heat def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, does not occur during a cellular response to heat." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein tyrosine phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein tyrosine phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein tyrosine phosphorylation during cellular response to heat shock" NARROW [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to heat" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002130 created_by: midori creation_date: 2013-06-13T11:34:25Z [Term] id: FYPO:0002284 name: obsolete abolished protein tyrosine phosphorylation during cellular response to hydrogen peroxide def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydrogen peroxide." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein tyrosine phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abolished protein tyrosine phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein tyrosine phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein tyrosine phosphorylation abolished during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0006232 created_by: midori creation_date: 2013-06-13T11:35:45Z [Term] id: FYPO:0002285 name: obsolete elongated cell during cellular response to hydrogen peroxide def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated during a cellular response to hydrogen peroxide." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated cell during cellular response to H2O2" EXACT [PomBase:mah] synonym: "elongated cell during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated cell during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "elongated in response to hydrogen peroxide" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2013-06-13T11:48:03Z [Term] id: FYPO:0002286 name: decreased RNA level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to osmotic stress is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased mRNA level during cellular response to osmotic stress" NARROW [PomBase:mah] synonym: "decreased RNA level during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to osmotic stress" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0003198 ! altered RNA level during cellular response to osmotic stress created_by: midori creation_date: 2013-06-13T13:09:14Z [Term] id: FYPO:0002287 name: decreased RNA level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to heat shock" NARROW [PomBase:mah] synonym: "decreased transcript level during cellular response to heat" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-06-13T13:13:48Z [Term] id: FYPO:0002288 name: obsolete abolished protein tyrosine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished peptidyl-tyrosine phosphorylation during vegetative growth" EXACT [GO:0018108] synonym: "abolished protein tyrosine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein tyrosine phosphorylation abolished during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002033 created_by: midori creation_date: 2013-06-13T13:37:19Z [Term] id: FYPO:0002289 name: abolished protein phosphorylation during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to osmotic stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-06-13T13:50:17Z [Term] id: FYPO:0002290 name: normal protein phosphorylation during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal during a cellular response to osmotic stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-06-13T14:47:01Z [Term] id: FYPO:0002291 name: obsolete normal protein tyrosine phosphorylation during cellular response to heat def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to heat." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "normal protein tyrosine phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein tyrosine phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002130 created_by: midori creation_date: 2013-06-13T14:47:56Z [Term] id: FYPO:0002292 name: obsolete viable tapered vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable and taper at one end to a diameter smaller than the other, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "population of tapered viable cells" EXACT [PomBase:vw] synonym: "viable bottle/skittle vegetative cell population" EXACT [PomBase:mah] synonym: "viable skittle-shaped vegetative cell population" EXACT [PomBase:mah] synonym: "viable vegetative cell population with skittle shaped cells" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-06-13T14:56:49Z [Term] id: FYPO:0002293 name: obsolete viable mixed population including curved cells def: "OBSOLETE. A mixed population phenotype in which cells in the population are viable, and some cells are curved along the long axis." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-06-13T15:02:16Z [Term] id: FYPO:0002294 name: inviable after spore germination with elongated germ tube and cell lysis def: "A phenotype in which a spore germinates to produce an elongated germ tube, but does not go on to form a viable dividing cell, and instead lyses." [PomBase:mah] synonym: "inviable after spore germination with elongated cell and cell lysis" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, with elongated germ tube and cell lysis" EXACT [PomBase:mah] synonym: "inviable germinated spore with elongated germ tube and cell lysis" EXACT [PomBase:mah] synonym: "lethal after spore germination with elongated germ tube and cell lysis" EXACT [PomBase:mah] synonym: "lysed cell after spore germination with elongated germ tube" EXACT [PomBase:vw] is_a: FYPO:0000647 ! vegetative cell lysis is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube relationship: has_part FYPO:0000647 ! vegetative cell lysis created_by: midori creation_date: 2013-06-13T15:12:40Z [Term] id: FYPO:0002295 name: obsolete mitotic catastrophe with cut, elongated cell during cellular response to hydroxyurea def: "OBSOLETE. An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when longer than wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the cut/morphology term with conditions specified. synonym: "cut with mitotic catastrophe, elongated cell during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, elongated cell during cellular response to HU" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, elongated cell during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe with cut, elongated cell during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, long cell" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-06-13T15:21:02Z [Term] id: FYPO:0002296 name: cone-shaped colony morphology def: "A colony morphology phenotype in which the colony spreads laterally to a lesser extent, and grows vertically to a greater extent, resulting in a more conical shape, than a wild-type colony." [PomBase:jh, PomBase:mah] synonym: "piled-up colony morphology" EXACT [PomBase:jh, PomBase:vw] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2013-06-13T15:37:00Z [Term] id: FYPO:0002297 name: dispersed actin cortical patch localization during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized throughout the cell cortex (rather than concentrated at the cell ends as in wild type cells) during interphase of the mitotic cell cycle." [PMID:8834798, PomBase:mah] synonym: "delocalised actin cortical patches during mitotic interphase" EXACT [PomBase:vw] synonym: "delocalized actin cortical patches during mitotic interphase" EXACT [PomBase:vw] synonym: "dispersed actin cortical patch localisation during mitotic interphase" EXACT [PomBase:mah] synonym: "dispersed actin cortical patch localization during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "dispersed actin cortical patch localization during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "dispersed actin cortical patch location during mitotic interphase" RELATED [PomBase:mah] synonym: "dispersed actin patch localization during mitotic interphase" EXACT [PomBase:mah] synonym: "dispersed F-actin patch localization during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0002021 ! dispersed actin cortical patch localization during vegetative growth created_by: midori creation_date: 2013-06-13T16:13:52Z [Term] id: FYPO:0002298 name: obsolete inviable mixed population including divided and undivided germinated spores, with elongated germ tubes def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable germinated spores with elongated germ tubes, and in which some cells divide once and others do not divide. In the cells that divide once, an inviable cell forms from the growing end of the germ tube, but does not divide further." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-06-20T11:41:51Z [Term] id: FYPO:0002299 name: obsolete inviable mixed population including divided and undivided germinated spores, with curved germ tubes def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable germinated spores with curved germ tubes, and in which some cells divide once and others do not divide. In the cells that divide once, an inviable cell forms from the growing end of the germ tube, but does not divide further." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-06-20T11:44:24Z [Term] id: FYPO:0002300 name: obsolete inviable mixed population including germinated spores with elongated germ tubes and elongated cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of germinated spores with elongated germ tubes and elongated vegetative cells. The elongated cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including germinated spores with elongated germ tubes and long cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-20T11:57:57Z [Term] id: FYPO:0002301 name: obsolete inviable microcolony, curved septated cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that are curved along the long axis and contain one or more septa. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, curved septated vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-06-20T13:28:56Z [Term] id: FYPO:0002302 name: inviable after spore germination, multiple cell divisions, spheroid cell def: "A phenotype in which a spore germinates to produce a cell that is spheroid, and undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, rounded cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, spheroid cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, spheroid cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, spheroid cell" EXACT [PomBase:mah] is_a: FYPO:0002148 ! inviable after spore germination, multiple cell divisions, abnormal morphology created_by: midori creation_date: 2013-06-20T13:52:46Z [Term] id: FYPO:0002303 name: inviable mononucleate monoseptate vegetative cell with anucleate compartment def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus." [PomBase:mah] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155), 'septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation' (FYPO:0003166), or their descendants, because these phenotypes often co-occur. synonym: "displaced nucleus with septum" RELATED [PMID:7798319] synonym: "inviable mononucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] synonym: "inviable mononucleate monoseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable with septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable with septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "inviable with septation without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "lethal; mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0006430 ! inviable mononucleate vegetative cell is_a: FYPO:0007664 ! mononucleate monoseptate vegetative cell with anucleate compartment relationship: has_part FYPO:0001225 ! monoseptate relationship: output_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2013-06-20T13:59:28Z [Term] id: FYPO:0002304 name: decreased RNA level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to salt stress" NARROW [PomBase:mah] synonym: "decreased RNA level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to salt stress" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-06-20T14:29:07Z [Term] id: FYPO:0002305 name: decreased RNA level during cellular response to non-ionic osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to non-ionic osmotic stress is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to non-ionic osmotic stress" NARROW [PomBase:mah] synonym: "decreased RNA level during cellular response to non-ionic osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to non-ionic osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to non-ionic osmotic stress" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-06-20T14:30:30Z [Term] id: FYPO:0002306 name: abnormal 5-phosphoribose 1-diphosphate binding def: "A molecular function phenotype in which occurrence of 5-phosphoribose 1-diphosphate binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds 5-phosphoribose 1-diphosphate differently from wild type, or that a mutation in one gene affects 5-phosphoribose 1-diphosphate binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "abnormal 5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding" EXACT [CHEBI:17111] synonym: "abnormal phosphoribosylpyrophosphate binding" EXACT [PomBase:al] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-06-20T15:05:41Z [Term] id: FYPO:0002307 name: increased 5-phosphoribose 1-diphosphate binding def: "A molecular function phenotype in which occurrence of 5-phosphoribose 1-diphosphate binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds 5-phosphoribose 1-diphosphate more than wild type, or that a mutation in one gene increases 5-phosphoribose 1-diphosphate binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "increased 5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding" EXACT [CHEBI:17111] synonym: "increased phosphoribosylpyrophosphate binding" EXACT [PomBase:al] is_a: FYPO:0002306 ! abnormal 5-phosphoribose 1-diphosphate binding created_by: midori creation_date: 2013-06-20T15:05:50Z [Term] id: FYPO:0002308 name: abnormal IMP binding def: "A molecular function phenotype in which occurrence of IMP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds IMP differently from wild type, or that a mutation in one gene affects IMP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-06-20T15:19:22Z [Term] id: FYPO:0002309 name: decreased IMP binding def: "A molecular function phenotype in which occurrence of IMP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced IMP binding" EXACT [PomBase:mah] is_a: FYPO:0002308 ! abnormal IMP binding created_by: midori creation_date: 2013-06-20T15:19:30Z [Term] id: FYPO:0002310 name: abnormal GMP binding def: "A molecular function phenotype in which occurrence of GMP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GMP differently from wild type, or that a mutation in one gene affects GMP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-06-20T15:19:22Z [Term] id: FYPO:0002311 name: decreased GMP binding def: "A molecular function phenotype in which occurrence of GMP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced GMP binding" EXACT [PomBase:mah] is_a: FYPO:0002310 ! abnormal GMP binding created_by: midori creation_date: 2013-06-20T15:21:09Z [Term] id: FYPO:0002312 name: resistance to ionizing radiation during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to ionizing radiation." [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "resistance to gamma irradiation during vegetative growth" NARROW [PomBase:mah] synonym: "resistance to gamma radiation during vegetative growth" NARROW [PomBase:mah] synonym: "resistance to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistant to ionizing radiation during vegetative growth" EXACT [GO:0009414, PomBase:al] synonym: "resistant to IR during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2013-06-20T15:28:55Z [Term] id: FYPO:0002313 name: ergosterol absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is too low to detect." [PomBase:mah] synonym: "ergosterol absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "ergosterol absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0002321 ! decreased cellular ergosterol level created_by: midori creation_date: 2013-06-21T14:32:23Z [Term] id: FYPO:0002314 name: GGPP absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-geranylgeranyl diphosphate (GGPP) measured in a cell is too low to detect." [PomBase:mah] synonym: "2-trans,6-trans,10-trans-geranylgeranyl diphosphate absent from cell" EXACT [CHEBI:48861] synonym: "all-trans-geranylgeranyl diphosphate absent from cell" EXACT [CHEBI:48861] synonym: "all-trans-geranylgeranyl pyrophosphate absent from cell" EXACT [CHEBI:48861] synonym: "GGPP absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "GGPP absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0002323 ! decreased cellular GGPP level created_by: midori creation_date: 2013-06-21T14:36:26Z [Term] id: FYPO:0002315 name: normal cellular FPP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-farnesyl diphosphate (FPP) measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular 2-trans,6-trans-farnesyl diphosphate level" EXACT [CHEBI:17407] synonym: "normal cellular farnesyl diphosphate level" BROAD [CHEBI:17407] synonym: "normal cellular farnesyl pyrophosphate level" BROAD [CHEBI:17407] synonym: "normal cellular FPP accumulation" RELATED [PomBase:mah] synonym: "normal cellular FPP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular FPP level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T14:40:55Z [Term] id: FYPO:0002316 name: normal cellular squalene level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of squalene measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular squalene accumulation" RELATED [PomBase:mah] synonym: "normal cellular squalene level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular squalene level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T14:47:33Z [Term] id: FYPO:0002317 name: increased cellular squalene level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of squalene measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular squalene level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular squalene level during vegetative growth" EXACT [PomBase:mah] synonym: "increased squalene accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T14:48:26Z [Term] id: FYPO:0002318 name: increased cellular ergosterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular ergosterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular ergosterol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased ergosterol accumulation" RELATED [PomBase:mah] is_a: FYPO:0002327 ! increased cellular sterol level created_by: midori creation_date: 2013-06-21T14:49:08Z [Term] id: FYPO:0002319 name: increased cellular lanosterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lanosterol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular lanosterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular lanosterol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased lanosterol accumulation" RELATED [PomBase:mah] is_a: FYPO:0002327 ! increased cellular sterol level created_by: midori creation_date: 2013-06-21T14:49:57Z [Term] id: FYPO:0002320 name: decreased cellular squalene level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of squalene measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular squalene level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular squalene level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased squalene accumulation" RELATED [PomBase:al] synonym: "reduced cellular squalene level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T14:51:34Z [Term] id: FYPO:0002321 name: decreased cellular ergosterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular ergosterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular ergosterol level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ergosterol accumulation" RELATED [PomBase:al] synonym: "reduced cellular ergosterol level" EXACT [PomBase:mah] is_a: FYPO:0002326 ! decreased cellular sterol level created_by: midori creation_date: 2013-06-21T14:52:35Z [Term] id: FYPO:0002322 name: decreased cellular FPP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-farnesyl diphosphate (FPP) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular 2-trans,6-trans-farnesyl diphosphate level" EXACT [CHEBI:17407] synonym: "decreased cellular farnesyl diphosphate level" BROAD [CHEBI:17407] synonym: "decreased cellular farnesyl pyrophosphate level" BROAD [CHEBI:17407] synonym: "decreased cellular FPP accumulation" RELATED [PomBase:mah] synonym: "decreased cellular FPP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular FPP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular FPP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T14:53:46Z [Term] id: FYPO:0002323 name: decreased cellular GGPP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-geranylgeranyl diphosphate (GGPP) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular 2-trans,6-trans,10-trans-geranylgeranyl diphosphate level" EXACT [CHEBI:48861] synonym: "decreased cellular all-trans-geranylgeranyl diphosphate level" EXACT [CHEBI:48861] synonym: "decreased cellular all-trans-geranylgeranyl pyrophosphate level" EXACT [CHEBI:48861] synonym: "decreased cellular GGPP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular GGPP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular GGPP level" EXACT [PomBase:mah] is_a: FYPO:0001289 ! decreased phospholipid level is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T14:55:28Z [Term] id: FYPO:0002324 name: decreased cellular lanosterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lanosterol measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular lanosterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular lanosterol level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ergosterol accumulation" RELATED [PomBase:al] synonym: "reduced cellular lanosterol level" EXACT [PomBase:mah] is_a: FYPO:0002326 ! decreased cellular sterol level created_by: midori creation_date: 2013-06-21T15:03:47Z [Term] id: FYPO:0002325 name: altered cellular sterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a sterol measured in a cell differs from normal. A sterol is any natural product derived from the steroid skeleton and containing a hydroxy group in the 3 position, closely related to cholestan-3-ol." [CHEBI:15889, PomBase:mah] synonym: "abnormal sterol level" EXACT [PomBase:mah] synonym: "altered cellular sterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered cellular sterol level during vegetative growth" EXACT [PomBase:mah] synonym: "altered sterol level" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2013-06-21T15:04:32Z [Term] id: FYPO:0002326 name: decreased cellular sterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a sterol measured in a cell is lower than normal. A sterol is any natural product derived from the steroid skeleton and containing a hydroxy group in the 3 position, closely related to cholestan-3-ol." [CHEBI:15889, PomBase:mah] synonym: "decreased cellular sterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular sterol level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sterol level" EXACT [PomBase:mah] synonym: "reduced cellular sterol level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0002325 ! altered cellular sterol level created_by: midori creation_date: 2013-06-21T15:06:49Z [Term] id: FYPO:0002327 name: increased cellular sterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a sterol measured in a cell is higher than normal. A sterol is any natural product derived from the steroid skeleton and containing a hydroxy group in the 3 position, closely related to cholestan-3-ol." [CHEBI:15889, PomBase:mah] synonym: "increased cellular sterol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular sterol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased sterol level" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0002325 ! altered cellular sterol level created_by: midori creation_date: 2013-06-21T15:07:56Z [Term] id: FYPO:0002328 name: sensitive to terbinafine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to terbinafine. Cells stop growing (and may die) at a concentration of terbinafine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to terbinafine" EXACT [PomBase:mah] synonym: "sensitive to terbinafine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to terbinafine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-06-21T15:16:32Z [Term] id: FYPO:0002329 name: normal growth on pravastatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing pravastatin." [PomBase:mah] synonym: "normal cell population growth in presence of pravastatin" EXACT [PomBase:mah] synonym: "normal cell population growth on pravastatin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to pravastatin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on pravastatin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-06-21T15:18:15Z [Term] id: FYPO:0002330 name: abnormal histone H3-K4 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "abnormal histone H3-K4 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K4me during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "abnormal histone lysine H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2013-06-21T15:36:29Z [Term] id: FYPO:0002331 name: increased histone H3-K4 dimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 4 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K4 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "increased histone H3-K4 dimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K4 dimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K4 dimethylation at centromere outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K4 dimethylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K4 dimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K4 dimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3K4 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K4me2 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0044648, PomBase:mah] is_a: FYPO:0005225 ! increased histone H3-K4 dimethylation during vegetative growth created_by: midori creation_date: 2013-06-21T17:31:19Z [Term] id: FYPO:0002332 name: normal protein localization to Golgi apparatus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to Golgi apparatus" EXACT [PomBase:mah] synonym: "normal protein localization to Golgi apparatus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to Golgi apparatus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-07-05T15:54:40Z [Term] id: FYPO:0002333 name: protein localization phenotype def: "A cell phenotype that affects the localization of a protein in a cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "cellular protein localization phenotype" EXACT [GO:0008104] synonym: "fission yeast protein localization phenotype" EXACT [PomBase:mah] synonym: "protein localisation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype created_by: midori creation_date: 2013-07-05T15:59:48Z [Term] id: FYPO:0002334 name: haploproficient def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a diploid cell with a single functional copy of a gene grows faster than a diploid with two (on no) functional copies." [PMID:23531409, PomBase:mah] synonym: "haploproficient during mitotic cell cycle" RELATED [PomBase:mah] synonym: "haploproficient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2013-07-05T16:12:09Z [Term] id: FYPO:0002335 name: normal chromatin silencing def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "normal chromatin silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2013-07-09T13:52:25Z [Term] id: FYPO:0002336 name: normal chromatin silencing at silent mating-type cassette def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "normal chromatin silencing at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "normal chromatin silencing at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002335 ! normal chromatin silencing created_by: midori creation_date: 2013-07-09T13:52:36Z [Term] id: FYPO:0002337 name: inviable elongated mononucleate vegetative cell with mislocalized nucleus def: "A cell phenotype in which a cell has one nucleus that is not in the normal location, is elongated, and is inviable." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable vegetative cell, with mislocalized mononucleus" EXACT [PomBase:vw] synonym: "inviable elongated mononucleate cell with abnormal nucleus location" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with abnormal nucleus position" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with displaced nucleus" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with mislocalised nucleus" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with mislocalized nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with misplaced nucleus" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate vegetative cell with asymmetrically localized nucleus" EXACT [PomBase:vw] synonym: "inviable elongated mononucleate vegetative cell with mislocalized nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable long mononucleate cell with mislocalized nucleus" EXACT [PomBase:vw] synonym: "inviable vegetative elongated mononucleate cell with mislocalized nucleus" EXACT [PomBase:mah] synonym: "lethal; elongated mononucleate vegetative cell with mislocalized nucleus" EXACT [PomBase:mah] is_a: FYPO:0004255 ! inviable elongated mononucleate vegetative cell is_a: FYPO:0006339 ! mononucleate vegetative cell with mislocalized nucleus created_by: midori creation_date: 2013-07-09T14:14:25Z [Term] id: FYPO:0002338 name: abnormal protein localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is abnormal. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the nuclear periphery and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "abnormal protein localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2013-07-09T14:38:16Z [Term] id: FYPO:0002339 name: decreased protein localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is decreased. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane." [GO:0034399, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "decreased protein localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nuclear periphery" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth is_a: FYPO:0002338 ! abnormal protein localization to nuclear periphery created_by: midori creation_date: 2013-07-09T14:39:15Z [Term] id: FYPO:0002340 name: decreased DNA recombination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is decreased." [PomBase:mah] synonym: "decreased DNA recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased DNA recombination frequency during vegetative growth" EXACT [PomBase:mah] synonym: "decreased DNA recombination rate during vegetative growth" RELATED [PomBase:mah] synonym: "decreased recombination during vegetative growth" EXACT [PomBase:vw] synonym: "reduced DNA recombination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth is_a: FYPO:0002712 ! decreased DNA recombination created_by: midori creation_date: 2013-07-09T15:19:36Z [Term] id: FYPO:0002341 name: increased duration of mitotic DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type." [PomBase:mah] synonym: "delayed mitotic DNA damage checkpoint deactivation" EXACT [PomBase:mah] synonym: "prolonged mitotic DNA damage checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal mitotic DNA damage checkpoint created_by: midori creation_date: 2013-07-09T15:43:06Z [Term] id: FYPO:0002342 name: septated vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cell contains one or more septa." [PomBase:mah] synonym: "septated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "septum present during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004296 ! septated cell created_by: midori creation_date: 2013-07-09T16:05:43Z [Term] id: FYPO:0002343 name: normal growth on terbinafine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing terbinafine." [PomBase:mah] synonym: "normal cell population growth in presence of terbinafine" EXACT [PomBase:mah] synonym: "normal cell population growth on terbinafine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to terbinafine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on terbinafine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-07-12T13:23:16Z [Term] id: FYPO:0002344 name: sensitive to phleomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity phleomycin. Cells stop growing (and may die) at a concentration of phleomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to phleomycin" EXACT [PomBase:mah] synonym: "sensitive to phleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to phleomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2013-07-12T14:33:03Z [Term] id: FYPO:0002345 name: sensitive to oxaliplatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxaliplatin. Cells stop growing (and may die) at a concentration of oxaliplatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to oxaliplatin" EXACT [PomBase:mah] synonym: "sensitive to oxaliplatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to oxaliplatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2013-07-12T14:43:28Z [Term] id: FYPO:0002346 name: abnormal chromatin silencing at centromere outer repeat def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the outer repeat region of the centromere is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abnormal centromere outer repeat region chromatin silencing" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromere outer repeat region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at centromere outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "abnormal chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "abnormal heterochromatic silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "abnormal heterochromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] is_a: FYPO:0000146 ! abnormal chromatin silencing at centromere created_by: midori creation_date: 2013-07-17T13:39:25Z [Term] id: FYPO:0002347 name: abnormal stress granule assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly is abnormal." [PMID:21098141, PomBase:mah] synonym: "abnormal cytoplasmic stress granule assembly during vegetative growth" EXACT [GO:0010494] synonym: "abnormal stress granule assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal stress granule formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth is_a: FYPO:0007318 ! abnormal stress granule assembly created_by: midori creation_date: 2013-07-17T13:46:11Z [Term] id: FYPO:0002348 name: abolished stress granule assembly during vegetative growth def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly does not occur." [PMID:21098141, PomBase:mah] synonym: "abolished cytoplasmic stress granule assembly during vegetative growth" EXACT [GO:0010494] synonym: "abolished stress granule assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished stress granule formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002347 ! abnormal stress granule assembly during vegetative growth created_by: midori creation_date: 2013-07-17T13:46:22Z [Term] id: FYPO:0002349 name: delayed onset of stress granule assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly begins later than normal." [PMID:21098141, PomBase:mah] synonym: "delayed onset of cytoplasmic stress granule assembly during vegetative growth" EXACT [GO:0010494] synonym: "delayed onset of stress granule assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of stress granule formation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed stress granule assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002347 ! abnormal stress granule assembly during vegetative growth created_by: midori creation_date: 2013-07-17T13:46:41Z [Term] id: FYPO:0002350 name: normal stress granule assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly is normal (i.e. indistinguishable from wild type)." [PMID:21098141, PomBase:mah] synonym: "normal cytoplasmic stress granule assembly during vegetative growth" EXACT [GO:0010494] synonym: "normal stress granule assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal stress granule formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2013-07-17T13:47:03Z [Term] id: FYPO:0002351 name: abnormal stress granule disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule disassembly is abnormal." [PMID:21098141, PomBase:mah] synonym: "abnormal cytoplasmic stress granule disassembly" EXACT [GO:0010494] synonym: "abnormal stress granule disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal stress granule disassembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2013-07-17T13:54:28Z [Term] id: FYPO:0002352 name: delayed onset of stress granule disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule disassembly begins later than normal." [PMID:21098141, PomBase:mah] synonym: "delayed onset of cytoplasmic stress granule disassembly" EXACT [GO:0010494] synonym: "delayed onset of stress granule disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of stress granule disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed stress granule disassembly" EXACT [PomBase:mah] is_a: FYPO:0002351 ! abnormal stress granule disassembly created_by: midori creation_date: 2013-07-17T13:54:45Z [Term] id: FYPO:0002353 name: decreased chromatin silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is decreased. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "decreased chromatin silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing during vegetative growth" EXACT [PomBase:mah] synonym: "reduced chromatin silencing" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing is_a: FYPO:0000576 ! decreased gene silencing created_by: midori creation_date: 2013-07-17T14:02:17Z [Term] id: FYPO:0002354 name: increased level of heterochromatin-encoded proteins def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by heterochromatic genes that are normally silenced is higher than normal." [PMID:22683269, PomBase:mah] synonym: "increased level of heterochromatin-encoded proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of heterochromatin-encoded proteins during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2013-07-17T14:51:57Z [Term] id: FYPO:0002355 name: decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased silent mating-type cassette histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation during vegetative growth is_a: FYPO:0007373 ! abnormal histone methylation at silent mating-type cassette during vegetative growth created_by: midori creation_date: 2013-07-17T15:07:34Z [Term] id: FYPO:0002356 name: normal methylated histone residue binding def: "A molecular function phenotype in which occurrence of binding by a gene product to a methylated histone residue in a protein is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is tested in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000702 ! protein-protein interaction phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2013-07-17T15:22:37Z [Term] id: FYPO:0002357 name: normal protein-RNA interaction def: "A molecular function phenotype in which an interaction between a protein and RNA is normal (i.e. indistinguishable from wild type). One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "normal RNA binding" EXACT [PomBase:mah] synonym: "normal RNA-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0002131 ! protein-RNA interaction phenotype created_by: midori creation_date: 2013-07-18T15:19:00Z [Term] id: FYPO:0002358 name: normal histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me2 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "normal silent mating-type cassette histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2013-07-18T15:21:48Z [Term] id: FYPO:0002359 name: normal histone H3-K9 dimethylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in telomeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me2 at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "normal telomeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2013-07-18T15:22:54Z [Term] id: FYPO:0002360 name: normal chromatin silencing at centromere def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "normal chromatin silencing at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002335 ! normal chromatin silencing created_by: midori creation_date: 2013-07-18T15:28:31Z [Term] id: FYPO:0002361 name: abnormal histone H3 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation is abnormal." [PomBase:mah] synonym: "abnormal histone H3 acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000456 ! abnormal histone acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T11:17:27Z [Term] id: FYPO:0002362 name: decreased histone H3 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone H3 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T11:18:01Z [Term] id: FYPO:0002363 name: increased histone H3 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T11:18:14Z [Term] id: FYPO:0002364 name: abnormal histone H4 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation is abnormal." [PomBase:mah] synonym: "abnormal histone H4 acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000456 ! abnormal histone acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T11:27:40Z [Term] id: FYPO:0002365 name: increased histone H4 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4 acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002364 ! abnormal histone H4 acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T11:27:49Z [Term] id: FYPO:0002366 name: decreased histone H3-K4 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "decreased histone H3-K4 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K4me during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "decreased histone lysine H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "reduced histone H3-K4 methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000870 ! decreased histone methylation during vegetative growth created_by: midori creation_date: 2013-07-25T12:16:12Z [Term] id: FYPO:0002367 name: decreased histone H3-K4 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K4 dimethylation during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "decreased histone H3-K4 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K4 dimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K4me2 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K4 dimethylation during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "reduced histone H3-K4 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002366 ! decreased histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2013-07-25T12:16:23Z [Term] id: FYPO:0002368 name: decreased histone H3-K4 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K4 trimethylation during vegetative growth" EXACT [GO:0080182, PomBase:mah] synonym: "decreased histone H3-K4 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K4 trimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K4me3 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K4 trimethylation during vegetative growth" EXACT [GO:0080182, PomBase:mah] synonym: "reduced histone H3-K4 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002366 ! decreased histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2013-07-25T12:16:39Z [Term] id: FYPO:0002369 name: increased histone H3-K56 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "abnormal histone H3-K56 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K56 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K56 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3-K56 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K56 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K56 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0097043, PomBase:vw] is_a: FYPO:0008270 ! increased H3-K56 acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T12:41:15Z [Term] id: FYPO:0002370 name: increased histone H3-K56 acetylation in transcribed regions during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 in regions of the genome that are actively transcribed occurs to a greater extent than normal." [PMID:23851719, PomBase:mah] synonym: "increased histone H3-K56 acetylation in transcribed regions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K56 acetylation in transcribed regions during vegetative growth" EXACT [GO:0097043, PomBase:vw] is_a: FYPO:0002363 ! increased histone H3 acetylation during vegetative growth created_by: midori creation_date: 2013-07-25T12:43:03Z [Term] id: FYPO:0002371 name: obsolete inviable mixed population including spores, undivided germinated spores and divided germinated spores def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of spores, undivided germinated spores, and germinated spores that go on to divide once or twice. Some germinated spores remain septated and do not complete cell division." [PomBase:jh, PomBase:mah] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including spores and undivided and divided germinated spores" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-07-25T13:32:16Z [Term] id: FYPO:0002372 name: obsolete viable spheroid vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable and are shaped in the form of spheroids." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "population of spheroid viable cells" EXACT [PomBase:vw] synonym: "viable rounded vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-07-25T13:38:18Z [Term] id: FYPO:0002373 name: abnormal actin cortical patch localization during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is abnormal during mitosis." [PomBase:mah] synonym: "abnormal actin cortical patch localisation during mitosis" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch localization during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch localization during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch localization during mitotic M phase" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch localization during mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal actin cortical patch location during mitosis" RELATED [PomBase:mah] synonym: "abnormal actin patch localization during mitosis" EXACT [PomBase:mah] synonym: "abnormal actin patch localization during mitosis" EXACT [PomBase:vw] synonym: "abnormal F-actin patch localization during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth created_by: midori creation_date: 2013-07-25T13:44:30Z [Term] id: FYPO:0002374 name: abnormal actin cortical patch morphology during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cortical patches is abnormal during mitosis." [PomBase:mah] synonym: "abnormal actin cortical patch morphology during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch morphology during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch morphology during mitotic M phase" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch morphology during mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal actin patch morphology during mitosis" EXACT [PomBase:mah] synonym: "abnormal F-actin patch morphology during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000791 ! abnormal actin cortical patch morphology created_by: midori creation_date: 2013-07-25T13:46:11Z [Term] id: FYPO:0002375 name: obsolete decreased protein tyrosine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-tyrosine phosphorylation during vegetative growth" EXACT [GO:0018108, PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tyrosine phosphorylation during vegetative growth" EXACT [PomBase:al] synonym: "reduced protein tyrosine phosphorylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001838 created_by: midori creation_date: 2013-07-25T14:54:57Z [Term] id: FYPO:0002376 name: decreased protein phosphorylation during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to osmotic stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased phosphorylation during cellular response to osmotic stress" EXACT [PomBase:al] synonym: "decreased protein phosphorylation during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-07-25T14:56:04Z [Term] id: FYPO:0002377 name: viable swollen vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "viable enlarged vegetative cell" RELATED [PomBase:mah] synonym: "viable large vegetative cell" RELATED [PomBase:vw] synonym: "viable swollen cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable swollen vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable vegetative cell with increased cell size" RELATED [PomBase:vw] synonym: "viable vegetative cell with increased cell volume" EXACT [PomBase:mah] is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0001491 ! viable vegetative cell relationship: has_part FYPO:0000646 ! swollen vegetative cell relationship: has_part FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2013-07-25T14:59:46Z [Term] id: FYPO:0002378 name: obsolete viable swollen vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable but have a greater length, diameter, and volume than normal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "viable enlarged vegetative cell population" RELATED [PomBase:mah] synonym: "viable large vegetative cell population" RELATED [PomBase:vw] synonym: "viable vegetative cell population with increased cell size" RELATED [PomBase:vw] synonym: "viable vegetative cell population with increased cell volume" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-07-25T15:02:36Z [Term] id: FYPO:0002379 name: inviable after spore germination, without cell division, with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable germinated spore, without cell division, with elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0000313 ! inviable after spore germination, without cell division, with abnormal germ tube morphology is_a: FYPO:0000314 ! inviable after spore germination with elongated germ tube is_a: FYPO:0004603 ! inviable after spore germination, without cell division, elongated cell created_by: midori creation_date: 2013-07-25T15:18:21Z [Term] id: FYPO:0002380 name: viable spheroid vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, and shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "spheroid viable cell" EXACT [PomBase:mah] synonym: "viable round vegetative cell" RELATED [PomBase:mah] synonym: "viable rounded vegetative cell" EXACT [PomBase:mah] synonym: "viable spheroid cell" EXACT [PomBase:mah] synonym: "viable spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000021 ! spheroid vegetative cell created_by: midori creation_date: 2013-07-25T16:27:44Z [Term] id: FYPO:0002381 name: increased histone H3 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal in centromere outer repeat regions." [PomBase:mah] synonym: "abnormal histone H3 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002363 ! increased histone H3 acetylation during vegetative growth created_by: midori creation_date: 2013-07-30T12:21:23Z [Term] id: FYPO:0002382 name: increased histone H4 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a greater extent than normal in centromere outer repeat regions." [PomBase:mah] synonym: "abnormal histone H4 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H4 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H4 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H4 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth created_by: midori creation_date: 2013-07-30T12:23:26Z [Term] id: FYPO:0002383 name: obsolete increased histone H3-K9 and H3-K14 acetylation at centromere outer repeat during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 9 and 14 of histone H3 in regions of the genome that are actively transcribed occurs to a greater extent than normal." [PMID:23851719, PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "increased histone H3 acetylation (K9 and K14) at centromere outer repeat during vegetative growth" EXACT [PMID:23851719] synonym: "increased histone H3-K9 and H3-K14 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 and H3-K14 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 and H3-K14 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 and H3-K14 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K9 and H3-K14 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3K9 and H3K14 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0000966 consider: FYPO:0006814 created_by: midori creation_date: 2013-07-30T12:39:07Z [Term] id: FYPO:0002384 name: obsolete increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at centromere outer repeat during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 5, 8, 12 and 16 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal." [PMID:23851719, PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "increased histone H4 acetylation (K5, K8, K12 and K16) at centromere outer repeat during vegetative growth" EXACT [PMID:23851719] synonym: "increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K5/8/12/16 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K5, H4K8, H4K12 and H4K16 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0007308 consider: FYPO:0007309 consider: FYPO:0007310 consider: FYPO:0007311 created_by: midori creation_date: 2013-07-30T12:44:38Z [Term] id: FYPO:0002385 name: decreased protein localization to heterochromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001131 ! abnormal protein localization to heterochromatin during vegetative growth created_by: midori creation_date: 2013-07-30T14:48:45Z [Term] id: FYPO:0002386 name: decreased protein localization to pericentric heterochromatin at centromere outer repeat region def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "deceased protein localization to heterochromatin at centromere otr" EXACT [PomBase:mah] synonym: "decreased protein localisation to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "decreased protein localization to centromere outer repeat heterochromatin" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at centromeric outer repeat" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at pericentromeric region" RELATED [PomBase:mah] is_a: FYPO:0008422 ! decreased protein localization to pericentric heterochromatin created_by: midori creation_date: 2013-07-30T14:55:26Z [Term] id: FYPO:0002387 name: decreased protein localization to subtelomeric heterochromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at subtelomeres is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to heterochromatin at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "reduced protein localization to subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002385 ! decreased protein localization to heterochromatin during vegetative growth is_a: FYPO:0005918 ! decreased protein localization to subtelomeric heterochromatin created_by: midori creation_date: 2013-07-30T14:57:37Z [Term] id: FYPO:0002388 name: abnormal riboflavin binding def: "A molecular function phenotype in which occurrence of riboflavin binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with riboflavin that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-10-16T11:29:35Z [Term] id: FYPO:0002389 name: normal protein localization to heterochromatin at centromere outer repeat alt_id: FYPO:0005081 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "normal protein localisation to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "normal protein localization at centromere otr" EXACT [PomBase:mah] synonym: "normal protein localization at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "normal protein localization at pericentric region" RELATED [PomBase:mah] synonym: "normal protein localization at pericentromeric region" RELATED [PomBase:mah] synonym: "normal protein localization to centromere outer repeat heterochromatin" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromere otr" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromeric outer repeat" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at pericentric region" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at pericentromeric region" RELATED [PomBase:mah] synonym: "normal protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to heterochromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008154 ! normal protein localization to centromeric heterochromatin created_by: midori creation_date: 2013-07-30T15:02:49Z [Term] id: FYPO:0002390 name: normal mitotic sister chromatid cohesion def: "A cellular process phenotype in which mitotic sister chromatid cohesion is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid cohesion is the process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle." [GO:0007064, PomBase:mah] synonym: "normal mitotic chromosome cohesion" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "normal sister chromatid cohesion during mitosis" EXACT [PomBase:mah] synonym: "normal sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2013-07-30T15:06:33Z [Term] id: FYPO:0002391 name: decreased protein localization to chromatin at rDNA alt_id: FYPO:0006350 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal DNA repeat regions is decreased." [PMID:24945319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at rDNA" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at ribosomal DNA" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at rRNA genes" EXACT [PomBase:mah] synonym: "decreased protein localization to rDNA" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at rDNA" EXACT [PomBase:mah] is_a: FYPO:0004346 ! decreased protein localization to chromatin at ncRNA genes created_by: midori creation_date: 2013-07-30T15:08:19Z [Term] id: FYPO:0002392 name: abnormal protein acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2013-07-30T15:31:06Z [Term] id: FYPO:0002393 name: abolished protein acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein acetylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein acetylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002392 ! abnormal protein acetylation during vegetative growth created_by: midori creation_date: 2013-07-30T15:31:44Z [Term] id: FYPO:0002394 name: decreased protein acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002392 ! abnormal protein acetylation during vegetative growth created_by: midori creation_date: 2013-07-30T15:32:01Z [Term] id: FYPO:0002395 name: decreased maintenance of protein localization to pericentric heterochromatin at centromere outer repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of localization of a protein at a location in heterochromatin at centromere outer repeat regions is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal maintenance of protein localization to heterochromatin at centromere otr" EXACT [PomBase:mah] synonym: "abnormal maintenance of protein localization to heterochromatin at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "abnormal maintenance of protein localization to heterochromatin at pericentric region" RELATED [PomBase:mah] synonym: "abnormal maintenance of protein localization to heterochromatin at pericentromeric region" RELATED [PomBase:mah] synonym: "decreased maintenance of protein localisation to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "decreased maintenance of protein localization to centromere outer repeat heterochromatin" EXACT [PomBase:mah] synonym: "decreased maintenance of protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased maintenance of protein localization to heterochromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "reduced maintenance of protein localization to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0002386 ! decreased protein localization to pericentric heterochromatin at centromere outer repeat region created_by: midori creation_date: 2013-07-30T15:38:11Z [Term] id: FYPO:0002396 name: normal maintenance of protein localization to heterochromatin at centromere outer repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of localization of a protein at a location in heterochromatin at centromere outer repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal maintenance of protein localisation to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "normal maintenance of protein localization to centromere outer repeat heterochromatin" EXACT [PomBase:mah] synonym: "normal maintenance of protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal maintenance of protein localization to heterochromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-07-30T15:39:37Z [Term] id: FYPO:0002397 name: abnormal cytoskeleton def: "A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in a physically abnormal cytoskeleton. synonym: "abnormal cytoskeleton physical object quality" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component relationship: output_of FYPO:0000802 ! abnormal cytoskeleton organization created_by: midori creation_date: 2013-07-30T17:06:41Z [Term] id: FYPO:0002398 name: abnormal actin cytoskeleton during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cytoskeleton physical object quality during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0005665 ! abnormal actin cytoskeleton relationship: output_of FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2013-07-30T17:07:07Z [Term] id: FYPO:0002399 name: abnormal microtubule cytoskeleton def: "A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in a physically abnormal microtubule cytoskeleton. synonym: "abnormal microtubule cytoskeleton physical object quality" EXACT [PomBase:mah] synonym: "disorganized microtubule cytoskeleton" RELATED [PomBase:vw] is_a: FYPO:0002397 ! abnormal cytoskeleton relationship: output_of FYPO:0000054 ! abnormal microtubule cytoskeleton organization created_by: midori creation_date: 2013-07-30T17:07:17Z [Term] id: FYPO:0002400 name: single microtubule bundle during mitotic interphase def: "A physical cellular phenotype observed during mitotic interphase in which all detectable microtubules are present in a single bundle." [PomBase:al, PomBase:mlr] synonym: "single microtubule array during mitotic interphase" EXACT [PomBase:vw] synonym: "single MT bundle during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2013-07-30T17:51:31Z [Term] id: FYPO:0002401 name: microtubule bundles present in increased numbers def: "A physical cellular phenotype in which cells contain more microtubule bundles than normal." [PomBase:mah] synonym: "extra microtubule bundles" EXACT [PomBase:mah] synonym: "increased level of MT bundles" EXACT [PomBase:al] synonym: "increased microtubule bundling" RELATED [PomBase:vw] synonym: "increased number of microtubule bundles" EXACT [PomBase:mah] synonym: "microtubule arrays present in increased numbers" RELATED [PomBase:vw] synonym: "microtubule bundles present in greater numbers" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2013-07-30T17:54:44Z [Term] id: FYPO:0002402 name: viable swollen vegetative cell with abnormal cell shape def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, and has an abnormal shape and a larger volume than normal." [PomBase:mah] synonym: "viable enlarged vegetative cell with abnormal cell shape" RELATED [PomBase:mah] synonym: "viable large vegetative cell with abnormal cell shape" RELATED [PomBase:vw] synonym: "viable swollen cell with abnormal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "viable swollen misshapen vegetative cell" RELATED [PomBase:mah] synonym: "viable swollen vegetative cell with abnormal cell shape during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable vegetative cell with increased cell size and abnormal cell shape" RELATED [PomBase:vw] synonym: "viable vegetative cell with increased cell volume and abnormal cell shape" EXACT [PomBase:mah] is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape is_a: FYPO:0002377 ! viable swollen vegetative cell created_by: midori creation_date: 2013-07-31T13:21:10Z [Term] id: FYPO:0002403 name: abnormal nucleus def: "A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the nucleus is abnormal." [PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in a physically abnormal cytoskeleton. synonym: "abnormal nucleus physical object quality" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2013-07-31T13:30:02Z [Term] id: FYPO:0002404 name: abnormal endomembrane system def: "A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the endomembrane system is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal endomembrane system during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal endomembrane system during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal endomembrane system physical object quality" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2013-07-31T13:34:35Z [Term] id: FYPO:0002405 name: viable curved stubby vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable and is curved along the long axis, and the cell diameter is larger than normal and the cell length is shorter than normal. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved stubby viable cell" EXACT [PomBase:mah] synonym: "viable curved stubby cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved stubby vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable curved watermelon-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002106 ! viable stubby vegetative cell is_a: FYPO:0002112 ! viable curved vegetative cell created_by: midori creation_date: 2013-07-31T13:45:31Z [Term] id: FYPO:0002406 name: viable curved stubby septated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, contains one or more septa, and is curved along the long axis, and the cell diameter is larger than normal and the cell length is shorter than normal. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved stubby septated viable cell" EXACT [PomBase:mah] synonym: "viable curved stubby septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved stubby septated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable curved watermelon-shaped septated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002342 ! septated vegetative cell is_a: FYPO:0002405 ! viable curved stubby vegetative cell relationship: has_part FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2013-07-31T13:49:44Z [Term] id: FYPO:0002407 name: obsolete viable curved stubby vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable and curved along the long axis, and the cell diameter is larger than normal and the cell length is shorter than normal, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "curved stubby viable vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-07-31T13:52:21Z [Term] id: FYPO:0002408 name: obsolete viable curved stubby septated vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are viable and curved along the long axis, contain one or more septa apiece, and the cell diameter is larger than normal and the cell length is shorter than normal, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "curved stubby septated viable vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002060 created_by: midori creation_date: 2013-07-31T14:08:02Z [Term] id: FYPO:0002409 name: inviable after spore germination, single cell division, with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and undergoes a single round of cell division." [PomBase:mah] synonym: "inviable after spore germination, single cell division, elongated cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, single cell division, with elongated, germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division, with elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division, with elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0000314 ! inviable after spore germination with elongated germ tube is_a: FYPO:0002420 ! inviable after spore germination, single cell division, abnormal cell shape created_by: midori creation_date: 2013-07-31T14:12:14Z [Term] id: FYPO:0002410 name: inviable vacuolated vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, cell shape is altered, and cell size remains normal, and in which vacuoles are more visible (usually by microscopy) than normal." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable vacuolated vegetative cell with abnormal cell shape and normal cell size" RELATED [PomBase:mah] synonym: "inviable vacuolated vegetative cell, abnormal cell shape, normal cell length" NARROW [PomBase:mah] synonym: "inviable vacuolated vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable vegetative misshapen vacuolated cell" RELATED [PomBase:vw] synonym: "inviable, vacuolated, abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] synonym: "lethal; vacuolated vegetative cell, abnormal cell shape, normal cell size" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001511 ! inviable vegetative cell, abnormal cell shape, normal cell size relationship: has_part FYPO:0001581 ! vacuolated created_by: midori creation_date: 2013-07-31T14:14:55Z [Term] id: FYPO:0002411 name: inviable curved elongated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved elongated inviable cell" EXACT [PomBase:mah] synonym: "inviable curved elongated cell" EXACT [PomBase:mah] synonym: "inviable curved elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable curved elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; curved elongated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002113 ! inviable curved vegetative cell is_a: FYPO:0005103 ! curved elongated vegetative cell created_by: midori creation_date: 2013-07-31T14:32:46Z [Term] id: FYPO:0002412 name: obsolete inviable curved elongated vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable, elongated, and curved along the long axis in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable curved long vegetative cell population" EXACT [PomBase:mah] synonym: "population of curved inviable long cells" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-07-31T14:33:01Z [Term] id: FYPO:0002413 name: obsolete inviable curved vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable and curved along the long axis in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable curved vegetative cell population" EXACT [PomBase:mah] synonym: "population of inviable curved cells" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-07-31T14:36:48Z [Term] id: FYPO:0002414 name: inviable swollen vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "inviable enlarged vegetative cell" RELATED [PomBase:mah] synonym: "inviable large vegetative cell" RELATED [PomBase:vw] synonym: "inviable swollen cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable vegetative cell with increased cell size" RELATED [PomBase:vw] synonym: "inviable vegetative cell with increased cell volume" EXACT [PomBase:mah] synonym: "lethal; swollen vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000646 ! swollen vegetative cell relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2013-07-31T15:54:54Z [Term] id: FYPO:0002415 name: inviable swollen vegetative cell with abnormal cell shape def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has an abnormal shape and a larger volume than normal." [PomBase:mah] synonym: "inviable enlarged vegetative cell with abnormal cell shape" RELATED [PomBase:mah] synonym: "inviable large vegetative cell with abnormal cell shape" RELATED [PomBase:vw] synonym: "inviable swollen cell with abnormal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen misshapen vegetative cell" RELATED [PomBase:mah] synonym: "inviable swollen vegetative cell with abnormal cell shape during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable vegetative cell with increased cell size and abnormal cell shape" RELATED [PomBase:vw] synonym: "inviable vegetative cell with increased cell volume and abnormal cell shape" EXACT [PomBase:mah] synonym: "lethal; swollen vegetative cell with abnormal cell shape" EXACT [PomBase:mah] is_a: FYPO:0002414 ! inviable swollen vegetative cell is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape created_by: midori creation_date: 2013-07-31T16:16:47Z [Term] id: FYPO:0002416 name: obsolete inviable microcolony, swollen cells, abnormal cell shape def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells in which cell shape is altered and cell volume is larger than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolonies swollen misshapen cells" RELATED [PomBase:vw] synonym: "inviable microcolony, enlarged vegetative cells with abnormal cell shape" RELATED [PomBase:mah] synonym: "inviable microcolony, large vegetative cells with abnormal cell shape" RELATED [PomBase:vw] synonym: "inviable microcolony, vegetative cells with increased cell size and abnormal cell shape" RELATED [PomBase:vw] synonym: "inviable microcolony, vegetative cells with increased cell volume and abnormal cell shape" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-07-31T16:24:46Z [Term] id: FYPO:0002417 name: obsolete inviable mixed population including spores and germinated spores with elongated germ tubes def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores and germinated spores with elongated germ tubes. The elongated cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-07-31T16:27:14Z [Term] id: FYPO:0002418 name: obsolete inviable mixed population including spores, germinated spores and elongated cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and elongated vegetative cells. The spheroid cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. synonym: "inviable mixed population including spores, germinated spores and long cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-07-31T16:33:44Z [Term] id: FYPO:0002419 name: obsolete inviable vegetative cell population after spore germination, without cell division def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, and do not divide before dying." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable germinated spore population, without cell division" EXACT [PomBase:mah] synonym: "inviable population of undivided germinated spores" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-07-31T16:40:46Z [Term] id: FYPO:0002420 name: inviable after spore germination, single cell division, abnormal cell shape def: "A phenotype in which a spore germinates to produce cell that has an abnormal shape and undergoes a single round of cell division." [PomBase:mah] synonym: "inviable following spore germination, single cell division, abnormal cell shape" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division, abnormal cell shape" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division, abnormal cell shape" EXACT [PomBase:mah] is_a: FYPO:0002280 ! inviable after spore germination, single cell division is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape created_by: midori creation_date: 2013-07-31T16:48:55Z [Term] id: FYPO:0002421 name: inviable after spore germination, single or double cell division, abnormal cell shape def: "A phenotype in which a spore germinates to produce a cell that has an abnormal shape and undergoes one or two rounds of cell division." [PomBase:mah] synonym: "inviable following spore germination, single or double cell division, abnormal cell shape" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell or double division, abnormal cell shape" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, abnormal cell shape" EXACT [PomBase:mah] is_a: FYPO:0001042 ! inviable after spore germination, single or double cell division is_a: FYPO:0002196 ! abnormal vegetative cell shape is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology relationship: has_part FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2013-07-31T16:57:30Z [Term] id: FYPO:0002422 name: obsolete inviable vegetative cell population after spore germination, single or double cell division, abnormal cell shape def: "OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, have an abnormal shape and undergo one or two rounds of cell division." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable germinated spore population, single or double cell division, abnormal cell shape" EXACT [PomBase:mah] synonym: "inviable population of germinated spores, single or double cell division, abnormal cell shape" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-07-31T16:58:52Z [Term] id: FYPO:0002423 name: inviable after spore germination, without cell division, septated cells with abnormal cell shape def: "A phenotype in which a spore germinates to produce an inviable cell that forms a septum but does not divide, and that has an abnormal shape." [PomBase:mah] synonym: "inviable after spore germination, septated undivided abnormally shaped cell" EXACT [PomBase:mah] synonym: "inviable after spore germination, undivided septated cells with abnormal cell shape" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, septated cells with abnormal cell shape" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, septated cells with abnormal cell shape" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, septated cells with abnormal cell shape" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology created_by: midori creation_date: 2013-07-31T17:14:02Z [Term] id: FYPO:0002424 name: normal actin cortical patch localization during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. Cortical patches are normally present at both old and new ends of the cell." [PomBase:mah] synonym: "normal actin cortical patch localisation during mitotic interphase" EXACT [PomBase:mah] synonym: "normal actin cortical patch localization at non-growing end during mitotic interphase" RELATED [PomBase:vw] synonym: "normal actin cortical patch localization during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal actin cortical patch location during mitotic interphase" RELATED [PomBase:mah] synonym: "normal actin patch localization during mitotic interphase" EXACT [PomBase:mah] synonym: "normal F-actin patch localization during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001294 ! normal actin cortical patch localization created_by: midori creation_date: 2013-08-01T17:10:00Z [Term] id: FYPO:0002425 name: abnormal actin cable organization during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cable organization is abnormal during mitosis. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cable. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [GO:0070648, PomBase:mah] synonym: "abnormal actin cable organisation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal actin cable organization during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cable organization during mitotic M phase" RELATED [PomBase:mah] synonym: "abnormal actin cable organization during mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal formin-nucleated actin cable organization during mitotic interphase" EXACT [GO:0070648] is_a: FYPO:0002030 ! abnormal actin cable organization created_by: midori creation_date: 2013-08-01T17:15:08Z [Term] id: FYPO:0002426 name: obsolete inviable mixed population including divided and undivided germinated spores def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable germinated spores, and in which some cells divide once and others do not divide. In the cells that divide once, an inviable cell forms from the growing end of the germ tube, but does not divide further." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-08-02T14:13:03Z [Term] id: FYPO:0002427 name: inviable spore with abnormal shape def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has an abnormal shape. An inviable spore does not germinate." [PomBase:mah] synonym: "lethal; spore with abnormal shape" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape is_a: FYPO:0002151 ! inviable spore created_by: midori creation_date: 2013-08-02T14:15:29Z [Term] id: FYPO:0002428 name: obsolete inviable mixed population including germinated spores with elongated germ tubes and cells with normal morphology def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of germinated spores with elongated germ tubes and vegetative cells of normal size and shape. The vegetative cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-08-02T15:25:58Z [Term] id: FYPO:0002429 name: inviable after spore germination, multiple cell divisions, abnormal cell shape, normal cell size def: "A phenotype in which a spore germinates to produce a cell of abnormal shape and normal size that undergoes two or more rounds of cell division and then dies." [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, abnormal cell shape, normal cell length" NARROW [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, abnormal cell shape, normal cell size" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, abnormal cell shape, normal cell size" EXACT [PomBase:mah] is_a: FYPO:0001511 ! inviable vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0002148 ! inviable after spore germination, multiple cell divisions, abnormal morphology is_a: FYPO:0002199 ! inviable vegetative cell with normal cell morphology created_by: midori creation_date: 2013-08-02T15:42:43Z [Term] id: FYPO:0002430 name: inviable after spore germination, multiple cell divisions def: "A phenotype in which a spore germinates to produce a cell that undergoes two or more rounds of cell division, and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions" EXACT [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2013-08-02T16:39:51Z [Term] id: FYPO:0002431 name: obsolete inviable mixed population including germinated spores with abnormal shape and cells with abnormal shape def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of germinated spores of abnormal shape and vegetative cells of abnormal shape. The vegetative cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-08-06T12:00:58Z [Term] id: FYPO:0002432 name: obsolete inviable mixed population including germinated spores and cells with abnormal shape def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of germinated spores and vegetative cells of abnormal shape. The vegetative cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-08-06T12:02:33Z [Term] id: FYPO:0002433 name: obsolete inviable vegetative cell population with abnormal cell shape def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable and have abnormal cell shape, in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable, abnormally shaped vegetative cell population" EXACT [PomBase:mah] synonym: "lethal; vegetative cell population with abnormal cell shape" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-08-06T12:07:07Z [Term] id: FYPO:0002434 name: short actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are shorter than normal." [PomBase:mah] synonym: "decreased actin cable length" EXACT [PomBase:mah] synonym: "short actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "short formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002031 ! abnormal actin cable morphology created_by: midori creation_date: 2013-08-06T12:19:34Z [Term] id: FYPO:0002435 name: abnormal actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] synonym: "abnormal actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth created_by: midori creation_date: 2013-08-06T12:25:22Z [Term] id: FYPO:0002436 name: misoriented actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the orientation of actin cables within a cell is abnormal." [PomBase:mah] synonym: "abnormal actin cable orientation" EXACT [PomBase:mah] synonym: "abnormal formin-nucleated actin cable orientation" EXACT [PomBase:mah] synonym: "misoriented actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "misoriented actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "misoriented formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002435 ! abnormal actin cables created_by: midori creation_date: 2013-08-06T12:31:15Z [Term] id: FYPO:0002437 name: thick actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are thicker than normal." [PomBase:mah] synonym: "increased actin cable thickness" EXACT [PomBase:mah] synonym: "thick actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "thick actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "thick formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002031 ! abnormal actin cable morphology created_by: midori creation_date: 2013-08-06T12:34:30Z [Term] id: FYPO:0002438 name: short, misoriented actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are shorter than normal and abnormally oriented within the cell." [PomBase:mah] synonym: "short, abnormally oriented actin cables" EXACT [PomBase:mah] synonym: "short, misoriented actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short, misoriented actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "short, misoriented formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002434 ! short actin cables is_a: FYPO:0002436 ! misoriented actin cables relationship: has_part FYPO:0002434 ! short actin cables relationship: has_part FYPO:0002436 ! misoriented actin cables created_by: midori creation_date: 2013-08-06T12:35:34Z [Term] id: FYPO:0002439 name: short, thick, misoriented actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are shorter and thicker than normal, and abnormally oriented within the cell." [PomBase:mah] synonym: "short, thick, abnormally oriented actin cables" EXACT [PomBase:mah] synonym: "short, thick, misoriented actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short, thick, misoriented actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "short, thick, misoriented formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002437 ! thick actin cables is_a: FYPO:0002438 ! short, misoriented actin cables relationship: has_part FYPO:0002437 ! thick actin cables created_by: midori creation_date: 2013-08-06T12:37:33Z [Term] id: FYPO:0002440 name: abnormal actin cable distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cable distribution is abnormal. The process normally establishes the spatial arrangement of actin cables within the cell. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] synonym: "abnormal actin cable distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cable distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cable localization" RELATED [Pombase:vw] synonym: "abnormal formin-nucleated actin cable distribution" EXACT [PomBase:mah] is_a: FYPO:0002030 ! abnormal actin cable organization created_by: midori creation_date: 2013-08-06T12:43:32Z [Term] id: FYPO:0002441 name: decreased rate of actin cable retrograde transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cable retrograde transport is lower than normal. The process normally arrangement of actin cables from the periphery toward the interior of the cell. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PMID:23051734, PomBase:mah] synonym: "decreased rate of actin cable retrograde transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actin cable retrograde transport during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of formin-nucleated actin cable retrograde flow" EXACT [PMID:23051734] synonym: "decreased rate of formin-nucleated actin cable retrograde transport" EXACT [PomBase:mah] synonym: "reduced rate of actin cable retrograde transport" EXACT [PomBase:mah] is_a: FYPO:0002440 ! abnormal actin cable distribution created_by: midori creation_date: 2013-08-06T12:45:13Z [Term] id: FYPO:0002442 name: normal protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell division site" EXACT [PomBase:mah] synonym: "normal protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein recruitment to cell division site" RELATED [PomBase:vw] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-08-06T12:50:51Z [Term] id: FYPO:0002443 name: normal rate of actin cable retrograde transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cable retrograde transport is normal (i.e. indistinguishable from wild type). The process results in arrangement of actin cables from the periphery toward the interior of the cell. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PMID:23051734, PomBase:mah] synonym: "normal rate of actin cable retrograde transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of actin cable retrograde transport during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of formin-nucleated actin cable retrograde flow" EXACT [PMID:23051734] synonym: "normal rate of formin-nucleated actin cable retrograde transport" EXACT [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2013-08-06T13:03:18Z [Term] id: FYPO:0002444 name: loss of punctate cytoplasmic protein localization def: "A cell phenotype in which a protein that is normally localized to discrete regions in the cytoplasm, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished punctate cytoplasmic protein localization" EXACT [PomBase:mah] synonym: "cytoplasmic dots absent" RELATED [PomBase:mah] synonym: "loss of punctate cytoplasmic protein localisation" EXACT [PomBase:mah] synonym: "loss of punctate cytoplasmic protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "loss of punctate cytoplasmic protein localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2013-08-06T13:54:47Z [Term] id: FYPO:0002445 name: protein mislocalized to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in actin cortical patches is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in actin cortical patches in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to actin cortical patch" EXACT [PomBase:vw] synonym: "protein mislocalised to actin cortical patch" EXACT [PomBase:mah] synonym: "protein mislocalised to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to actin patch" EXACT [PomBase:mah] synonym: "protein mislocalized to F-actin patch" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2013-08-06T13:56:32Z [Term] id: FYPO:0002446 name: decreased protein phosphorylation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-08-06T13:58:08Z [Term] id: FYPO:0002447 name: abnormal protein N-linked glycosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the N-glycosylation of one or more specific proteins, or of specific protein sites, is abnormal. Protein N-linked glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan." [GO:0006487, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein N-glycosylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein N-linked glycosylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001910 ! abnormal protein glycosylation during vegetative growth created_by: midori creation_date: 2013-08-06T13:59:25Z [Term] id: FYPO:0002448 name: normal Dsc complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Dsc E3 ubiquitin ligase complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal Dsc complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal Dsc complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal Dsc E3 ubiquitin ligase assembly" EXACT [GO:1990155] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2013-08-06T14:02:34Z [Term] id: FYPO:0002449 name: signal recognition particles present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer signal recognition particles (SRPs) than normal." [PomBase:mah] synonym: "decreased level of SRPs" RELATED [PomBase:al] synonym: "decreased signal recognition particle formation during vegetative growth" RELATED [PomBase:mah] synonym: "fewer signal recognition particles present during vegetative growth" EXACT [PomBase:mah] synonym: "signal recognition particles present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "signal recognition particles present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "signal recognition particles present in reduced numbers" EXACT [PomBase:mah] synonym: "SRPs present in decreased numbers" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2013-08-06T14:17:38Z [Term] id: FYPO:0002450 name: inviable after spore germination, multiple cell divisions, septated cell with abnormal morphology def: "A phenotype in which a spore germinates to produce a cell that is septated and has abnormal morphology (i.e. size, shape, or structure), and that undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, septated cell with abnormal morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, septated cell with abnormal morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, septated cell with abnormal morphology" EXACT [PomBase:mah] is_a: FYPO:0002148 ! inviable after spore germination, multiple cell divisions, abnormal morphology created_by: midori creation_date: 2013-08-06T14:25:13Z [Term] id: FYPO:0002451 name: inviable vegetative cell with abnormal cell shape def: "A cell phenotype in which a cell is inviable and cell shape is altered in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable vegetative cell with abnormal cell shape during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable, abnormal cell shape during vegetative growth" EXACT [PomBase:mah] synonym: "lethal; vegetative cell with abnormal cell shape" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell is_a: FYPO:0002196 ! abnormal vegetative cell shape relationship: has_part FYPO:0001126 ! abnormal cell shape relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2013-08-06T14:40:39Z [Term] id: FYPO:0002452 name: inviable septated vegetative cell with abnormal cell morphology def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell contains one or more septa, has abnormal morphology (i.e. size, shape, or structure) and is inviable." [PomBase:mah] synonym: "lethal; septated vegetative cell with abnormal cell morphology" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002342 ! septated vegetative cell relationship: has_part FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2013-08-06T14:42:46Z [Term] id: FYPO:0002453 name: obsolete inviable microcolony, septated cells with abnormal morphology def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have abnormal morphology (i.e. size, shape, or structure) and contain one or more septa apiece. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, septated vegetative cells with abnormal morphology" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-08-06T14:44:38Z [Term] id: FYPO:0002454 name: obsolete inviable vegetative cell population with abnormal cell morphology def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable and have abnormal cell morphology (i.e. size, shape, or structure), in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-08-06T14:46:31Z [Term] id: FYPO:0002455 name: abnormal septum during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position or morphology of all or part of the septum is abnormal." [PomBase:mah] comment: Note that an septum organization process may, but does not necessarily, result in a physically abnormal septum. synonym: "abnormal septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septum physical object quality during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0004292 ! abnormal septum created_by: midori creation_date: 2013-08-06T15:00:01Z [Term] id: FYPO:0002456 name: viable curved vegetative cell with abnormal septum def: "A cell morphology phenotype in which a vegetatively growing cell is viable, is curved along the long axis, and contains one or more abnormal septa. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved viable cell with abnormal septum" EXACT [PomBase:mah] synonym: "viable curved abnormally septated vegetative cell" EXACT [PomBase:mah, PomBase:vw] synonym: "viable curved cell with abnormal septum during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved vegetative cell with abnormal septum during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002112 ! viable curved vegetative cell is_a: FYPO:0002455 ! abnormal septum during vegetative growth relationship: has_part FYPO:0002455 ! abnormal septum during vegetative growth created_by: midori creation_date: 2013-08-06T15:04:59Z [Term] id: FYPO:0002457 name: viable curved elongated vegetative cell with abnormal septum def: "A cell morphology phenotype in which a vegetatively growing cell is viable, is elongated, is curved along the long axis, and contains one or more abnormal septa. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved elongated viable cell with abnormal septum" EXACT [PomBase:mah] synonym: "viable curved elongated abnormally septated vegetative cell" EXACT [PomBase:mah, PomBase:vw] synonym: "viable curved elongated cell with abnormal septum during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved elongated vegetative cell with abnormal septum during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002215 ! viable curved elongated vegetative cell is_a: FYPO:0002456 ! viable curved vegetative cell with abnormal septum created_by: midori creation_date: 2013-08-06T15:08:11Z [Term] id: FYPO:0002459 name: viable branched, elongated vegetative cell alt_id: FYPO:0002458 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, septated, and elongated." [PomBase:jh, PomBase:mah] synonym: "viable branched cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched elongated vegetative cell" EXACT [PomBase:vw] synonym: "viable branched vegetative cell" EXACT [PomBase:mah] synonym: "viable branched vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable branched, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable branched, elongated, septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "viable branched, long, septated cell" EXACT [PomBase:vw] synonym: "viable branched, septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "viable elongated branched cell" EXACT [PomBase:vw] is_a: FYPO:0001492 ! viable elongated vegetative cell is_a: FYPO:0004594 ! branched, elongated, septated cell created_by: midori creation_date: 2013-08-06T15:21:13Z [Term] id: FYPO:0002460 name: viable branched, curved, elongated vegetative cell alt_id: FYPO:0002477 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, septated, elongated, and is curved along the long axis." [PomBase:mah] synonym: "viable branched curved cell" EXACT [PomBase:vw] synonym: "viable branched, curved cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, curved septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "viable branched, curved vegetative cell" EXACT [PomBase:mah] synonym: "viable branched, curved vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable branched, curved, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, curved, elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable branched, elongated, curved septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "viable branched, long, curved, septated cell" EXACT [PomBase:vw] synonym: "viable curved branched cell" EXACT [PomBase:vw] synonym: "viable elongated branched curved cell" EXACT [PomBase:vw] is_a: FYPO:0002215 ! viable curved elongated vegetative cell is_a: FYPO:0002459 ! viable branched, elongated vegetative cell created_by: midori creation_date: 2013-08-06T15:25:18Z [Term] id: FYPO:0002462 name: inviable branched, elongated vegetative cell alt_id: FYPO:0002461 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, septated, and elongated." [PomBase:jh, PomBase:mah] synonym: "inviable branched cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched vegetative cell" EXACT [PomBase:mah] synonym: "inviable branched vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable branched, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable branched, elongated, septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable branched, long, septated cell" EXACT [PomBase:vw] synonym: "inviable branched, septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable elongated branched cell" EXACT [PomBase:vw] synonym: "lethal; branched, elongated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology is_a: FYPO:0004594 ! branched, elongated, septated cell created_by: midori creation_date: 2013-08-06T15:55:03Z [Term] id: FYPO:0002463 name: inviable branched, curved, elongated vegetative cell alt_id: FYPO:0002481 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, septated, elongated, and is curved along the long axis." [PomBase:mah] synonym: "inviable branched curved cell" EXACT [PomBase:vw] synonym: "inviable branched, curved cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, curved septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable branched, curved vegetative cell" EXACT [PomBase:mah] synonym: "inviable branched, curved vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable branched, curved, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, curved, elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable branched, elongated, curved septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable branched, long, curved, septated cell" EXACT [PomBase:vw] synonym: "inviable curved branched cell" EXACT [PomBase:vw] synonym: "inviable curved branched elongated cell" EXACT [PomBase:vw] synonym: "inviable elongated branched curved cell" EXACT [PomBase:vw] synonym: "lethal; branched, curved, elongated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002282 ! inviable curved septated vegetative cell is_a: FYPO:0002411 ! inviable curved elongated vegetative cell is_a: FYPO:0002462 ! inviable branched, elongated vegetative cell created_by: midori creation_date: 2013-08-06T15:55:34Z [Term] id: FYPO:0002464 name: obsolete inviable microcolony, branched, curved, elongated cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that are curved along the long axis, elongated, and branched (and septated). Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, branched, curved, elongated, septated vegetative cells" EXACT [PomBase:vw] synonym: "inviable microcolony, curved, branched, elongated cells" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-08-06T16:01:01Z [Term] id: FYPO:0002465 name: obsolete inviable spore population with abnormal spore shape def: "OBSOLETE. A cell population phenotype in which none of the cells in a population of spores are viable, and all have an abnormal shape. Inviable spores do not germinate." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable population of spores with abnormal shape" EXACT [PomBase:vw] synonym: "inviable spore population with abnormal shape" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002150 created_by: midori creation_date: 2013-08-06T16:15:29Z [Term] id: FYPO:0002466 name: obsolete inviable mixed population including spores, germinated spores and cells with abnormal morphology def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and cells with abnormal morphology (i.e. size, shape, or structure). The cells with normal morphology arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-08-06T16:17:57Z [Term] id: FYPO:0002467 name: abnormal spore shape def: "A cell phenotype in which a spore has an abnormal shape." [PomBase:mah] is_a: FYPO:0000348 ! abnormal spore morphology is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2013-08-06T16:31:13Z [Term] id: FYPO:0002468 name: obsolete inviable swollen elongated vegetative cell population def: "OBSOLETE. A cell population phenotype in which all cells in the population are inviable, have a larger volume and are longer than normal in the vegetative growth phase of the life cycle. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype plus a full-penetrance extension. synonym: "inviable elongated cell population with increased cell volume" EXACT [PomBase:mah] synonym: "inviable elongated swollen population" EXACT [PomBase:vw] synonym: "inviable enlarged elongated cell population" RELATED [PomBase:mah] synonym: "inviable large elongated cell population" RELATED [PomBase:vw] synonym: "inviable swollen long vegetative cell population" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002061 created_by: midori creation_date: 2013-08-08T11:06:30Z [Term] id: FYPO:0002469 name: obsolete inviable microcolony, elongated tapered cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that are longer than normal and taper at one end to a diameter smaller than the other. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, elongated bottle/skittle cells" EXACT [PomBase:mah] synonym: "inviable microcolony, elongated skittle-shaped cells" EXACT [PomBase:mah] synonym: "inviable microcolony, elongated tapered vegetative cells" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2013-08-08T11:17:14Z [Term] id: FYPO:0002470 name: decreased protein phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to IR" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-08-08T11:27:46Z [Term] id: FYPO:0002471 name: abolished protein phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to IR" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-08-08T11:33:54Z [Term] id: FYPO:0002472 name: abolished histone H2A phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of histone H2A does not occur during a cellular response to ionizing radiation." [PomBase:mah] synonym: "abolished H2A phosphorylation during cellular response to IR" EXACT [PomBase:al] synonym: "abolished histone H2A phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H2A phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H2A phosphorylation during cellular response to IR" EXACT [PomBase:mah] synonym: "histone H2A phosphorylation abolished during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "histone H2A phosphorylation abolished during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0002471 ! abolished protein phosphorylation during cellular response to ionizing radiation created_by: midori creation_date: 2013-08-08T11:33:54Z [Term] id: FYPO:0002473 name: abnormal protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at double-strand break sites and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "abnormal protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to DSB site" EXACT [PomBase:al] synonym: "abnormal protein localization to site of double-strand break" EXACT [GO:0035861, PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2013-08-08T12:23:37Z [Term] id: FYPO:0002474 name: decreased protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "decreased protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to DSB site" EXACT [PomBase:al] synonym: "decreased protein localization to site of double-strand break" EXACT [GO:0035861, PomBase:mah] synonym: "reduced protein localization to double-strand break site" EXACT [PomBase:mah] is_a: FYPO:0002473 ! abnormal protein localization to double-strand break site created_by: midori creation_date: 2013-08-08T12:23:48Z [Term] id: FYPO:0002475 name: increased protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "increased protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to DSB site" EXACT [PomBase:al] synonym: "increased protein localization to site of double-strand break" EXACT [GO:0035861, PomBase:mah] is_a: FYPO:0002473 ! abnormal protein localization to double-strand break site created_by: midori creation_date: 2013-08-08T12:24:07Z [Term] id: FYPO:0002476 name: viable vacuolated vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, cell shape is altered, and cell size remains normal, and in which vacuoles are more visible (usually by microscopy) than normal." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "viable vacuolated vegetative cell with abnormal cell shape and normal cell size" RELATED [PomBase:mah] synonym: "viable vacuolated vegetative cell, abnormal cell shape, normal cell length" NARROW [PomBase:mah] synonym: "viable vacuolated vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable vegetative misshapen vacuolated cell" RELATED [PomBase:vw] synonym: "viable, vacuolated, abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001510 ! viable vegetative cell, abnormal cell shape, normal cell size relationship: has_part FYPO:0001581 ! vacuolated created_by: midori creation_date: 2013-08-08T12:32:29Z [Term] id: FYPO:0002478 name: viable curved vacuolated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable and is curved along the long axis, and in which vacuoles are more visible (usually by microscopy) than normal. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved vacuolated viable cell" EXACT [PomBase:mah] synonym: "viable curved vacuolated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved vacuolated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002112 ! viable curved vegetative cell relationship: has_part FYPO:0001581 ! vacuolated created_by: midori creation_date: 2013-08-08T13:18:21Z [Term] id: FYPO:0002479 name: viable swollen elongated vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable and has a larger volume, and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "viable elongated cell with increased cell volume" EXACT [PomBase:mah] synonym: "viable enlarged elongated cell" RELATED [PomBase:mah] synonym: "viable large elongated cell" RELATED [PomBase:vw] synonym: "viable swollen elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable swollen elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0001429 ! swollen elongated cell is_a: FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2013-08-08T13:22:32Z [Term] id: FYPO:0002480 name: viable after spore germination with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and subsequently forms a viable dividing cell." [PomBase:mah] synonym: "viable following spore germination with elongated germ tube" EXACT [PomBase:mah] synonym: "viable germinated spore with elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell created_by: midori creation_date: 2013-08-08T13:37:23Z [Term] id: FYPO:0002482 name: inviable spheroid vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "inviable round vegetative cell" RELATED [PomBase:mah] synonym: "inviable rounded vegetative cell" EXACT [PomBase:mah] synonym: "inviable spheroid cell" EXACT [PomBase:mah] synonym: "inviable spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; spheroid vegetative cell" EXACT [PomBase:mah] synonym: "spheroid inviable cell" EXACT [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000021 ! spheroid vegetative cell created_by: midori creation_date: 2013-08-08T13:50:47Z [Term] id: FYPO:0002483 name: inviable small tapered vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, has an abnormally low volume, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable small bottle-shaped vegetative cell" EXACT [PomBase:vw] synonym: "inviable small bottle-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable small bottle/skittle vegetative cell" EXACT [PomBase:mah] synonym: "inviable small skittle-shaped vegetative cell" EXACT [PomBase:mah] synonym: "inviable small tapered cell during vegetative growth" EXACT [PomBase:mah] synonym: "lethal; small tapered vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000951 ! inviable small vegetative cell is_a: FYPO:0002111 ! inviable tapered vegetative cell created_by: midori creation_date: 2013-08-08T13:58:49Z [Term] id: FYPO:0002484 name: increased intergenic meiotic recombination alt_id: FYPO:0005374 def: "A cellular process phenotype in which the occurrence of two meiotic reciprocal recombination events (crossovers) close to each other is incresed. As a result, the resolution of meiotic recombination intermediates results in the formation of a crossover at a higher frequency than normal, and the occurrence of intergenic meiotic recombination is increased." [PMID:11726502, PMID:22723423, PomBase:gs, PomBase:mah] synonym: "increased meiotic intergenic recombination" EXACT [PMID:16169489, PomBase:al] synonym: "increased occurrence of meiotic cross-overs" RELATED [PMID:22723423, PomBase:al] synonym: "increased resolution of meiotic recombination intermediates with crossover formation" EXACT [PomBase:mah] is_a: FYPO:0000487 ! increased meiotic recombination created_by: midori creation_date: 2013-08-08T14:57:12Z [Term] id: FYPO:0002485 name: decreased intergenic meiotic recombination alt_id: FYPO:0003180 def: "A cellular process phenotype in which the occurrence of two meiotic reciprocal recombination events (crossovers) close to each other is decresed. As a result, the resolution of meiotic recombination intermediates results in the formation of a crossover at a lower frequency than normal, and the occurrence of intergenic meiotic recombination is decreased." [PMID:16169489, PMID:22723423, PomBase:gs, PomBase:mah] synonym: "decreased meiotic intergenic recombination" EXACT [PMID:16169489, PomBase:al] synonym: "decreased occurrence of meiotic cross-overs" RELATED [PMID:22723423, PomBase:al] synonym: "decreased resolution of meiotic recombination intermediates with crossover formation" EXACT [PomBase:mah] synonym: "reduced intergenic meiotic recombination" EXACT [PomBase:mah] synonym: "reduced resolution of meiotic recombination intermediates with crossover formation" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2013-08-08T15:07:01Z [Term] id: FYPO:0002486 name: decreased meiotic strand displacement def: "A cellular process phenotype in which the occurrence of meiotic strand displacement is decreased. Meiotic strand displacement is the part of meiotic recombination in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected." [GO:0000714, PMID:22723423, PomBase:mah] synonym: "decreased D-loop unwinding" RELATED [PMID:22723423, PomBase:al] synonym: "decreased meiotic D-loop dissociation" EXACT [GO:0000714] synonym: "decreased meiotic D-loop processing" RELATED [GO:0000714] synonym: "reduced meiotic strand displacement" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2013-08-08T15:07:43Z [Term] id: FYPO:0002487 name: normal actin cable morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of actin cables are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin cable morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actin cable morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal formin-nucleated actin cable morphology" EXACT [GO:0070648] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2013-08-08T15:14:52Z [Term] id: FYPO:0002488 name: cell lysis def: "An inviable phenotype in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] synonym: "cytolysis" EXACT [PomBase:mah] synonym: "inviable, lysed cell" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell relationship: has_part FYPO:0000049 ! inviable cell created_by: midori creation_date: 2013-08-08T15:17:46Z [Term] id: FYPO:0002489 name: spore lysis def: "An inviable phenotype in which a spore lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] synonym: "inviable, lysed spore" EXACT [PomBase:vw] synonym: "spore cytolysis" EXACT [PomBase:mah] is_a: FYPO:0002151 ! inviable spore is_a: FYPO:0002488 ! cell lysis relationship: has_part FYPO:0002151 ! inviable spore created_by: midori creation_date: 2013-08-08T15:26:41Z [Term] id: FYPO:0002490 name: inviable after spore germination, multiple cell divisions, swollen cell def: "A phenotype in which a spore germinates to produce a cell that has a greater length, diameter, and volume than normal, and undergoes two or more rounds of cell division and then dies. The ratio between cell length and diameter remains normal." [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, enlarged cell" RELATED [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, increased cell size" RELATED [PomBase:vw] synonym: "inviable after spore germination, multiple cell divisions, increased cell volume" EXACT [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, large cell" RELATED [PomBase:vw] synonym: "inviable following spore germination, multiple cell divisions, swollen cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, swollen cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, swollen cell" EXACT [PomBase:mah] is_a: FYPO:0002148 ! inviable after spore germination, multiple cell divisions, abnormal morphology created_by: midori creation_date: 2013-08-08T15:29:22Z [Term] id: FYPO:0002491 name: abnormal DNA 5'-adenosine monophosphate hydrolase activity def: "A molecular function phenotype in which the observed rate of DNA 5'-adenosine monophosphate hydrolase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-08-08T15:38:20Z [Term] id: FYPO:0002492 name: abolished DNA 5'-adenosine monophosphate hydrolase activity def: "A molecular function phenotype in which DNA 5'-adenosine monophosphate hydrolase activity is absent." [PomBase:mah] synonym: "DNA 5'-adenosine monophosphate hydrolase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002491 ! abnormal DNA 5'-adenosine monophosphate hydrolase activity created_by: midori creation_date: 2013-08-08T15:38:33Z [Term] id: FYPO:0002493 name: decreased DNA 5'-adenosine monophosphate hydrolase activity def: "A molecular function phenotype in which the observed rate of DNA 5'-adenosine monophosphate hydrolase activity is decreased." [PomBase:mah] synonym: "reduced DNA 5'-adenosine monophosphate hydrolase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002491 ! abnormal DNA 5'-adenosine monophosphate hydrolase activity created_by: midori creation_date: 2013-08-08T15:38:46Z [Term] id: FYPO:0002494 name: abnormal protein modification def: "A cellular process phenotype in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002274 ! abnormal protein metabolic process created_by: midori creation_date: 2013-08-08T15:45:44Z [Term] id: FYPO:0002495 name: normal protein modification def: "A cellular process phenotype in which protein modification is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0004849 ! normal protein metabolic process created_by: midori creation_date: 2013-08-08T15:49:50Z [Term] id: FYPO:0002496 name: normal metabolic process def: "A cellular process phenotype in which a cellular metabolic process is normal (i.e. indistinguishable from wild type). A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal cellular metabolic process" EXACT [GO:0044237, PomBase:mah] synonym: "normal metabolism" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2013-08-08T15:51:57Z [Term] id: FYPO:0002497 name: abolished protein modification def: "A cellular process phenotype in which protein modification does not occur. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein/peptide modification" EXACT [PomBase:mah] synonym: "absent protein/peptide modification" EXACT [PomBase:mah] synonym: "protein modification abolished" EXACT [PomBase:mah] synonym: "protein/peptide modification: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2013-08-08T15:57:24Z [Term] id: FYPO:0002498 name: decreased protein modification def: "A cellular process phenotype in which the occurrence of protein modification is decreased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced protein modification" EXACT [PomBase:mah] is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2013-08-08T15:59:37Z [Term] id: FYPO:0002499 name: increased protein modification def: "A cellular process phenotype in which the occurrence of protein modification is increased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2013-08-08T15:59:46Z [Term] id: FYPO:0002500 name: normal protein palmitoylation def: "A cellular process phenotype in which protein palmitoylation is normal (i.e. indistinguishable from wild type). Protein palmitoylation is the addition of a palmitoyl group to a protein amino acid." [GO:0018345, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein/peptide palmitoylation" EXACT [PomBase:mah] is_a: FYPO:0002495 ! normal protein modification created_by: midori creation_date: 2013-08-08T16:06:16Z [Term] id: FYPO:0002501 name: normal protein palmitoylation during meiosis def: "A cellular process phenotype in which protein palmitoylation is normal (i.e. indistinguishable from wild type) during one or both meiotic nuclear divisions. Protein palmitoylation is the addition of a palmitoyl group to a protein amino acid." [GO:0018345, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein palmitoylation during meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal protein/peptide palmitoylation during meiosis" EXACT [PomBase:mah] is_a: FYPO:0002500 ! normal protein palmitoylation created_by: midori creation_date: 2013-08-08T16:07:40Z [Term] id: FYPO:0002502 name: normal protein palmitoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein palmitoylation is normal (i.e. indistinguishable from wild type). Protein palmitoylation is the addition of a palmitoyl group to a protein amino acid." [GO:0018345, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein palmitoylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide palmitoylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth is_a: FYPO:0002500 ! normal protein palmitoylation created_by: midori creation_date: 2013-08-08T16:08:20Z [Term] id: FYPO:0002503 name: abnormal protein palmitoylation def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2013-08-08T16:09:58Z [Term] id: FYPO:0002504 name: abolished protein palmitoylation def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein palmitoylation abolished" EXACT [PomBase:mah] synonym: "protein palmitoylation absent" EXACT [PomBase:al] is_a: FYPO:0002497 ! abolished protein modification is_a: FYPO:0002503 ! abnormal protein palmitoylation created_by: midori creation_date: 2013-08-08T16:11:12Z [Term] id: FYPO:0002505 name: decreased protein palmitoylation def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "reduced protein palmitoylation" EXACT [PomBase:mah] is_a: FYPO:0002498 ! decreased protein modification is_a: FYPO:0002503 ! abnormal protein palmitoylation created_by: midori creation_date: 2013-08-08T16:11:34Z [Term] id: FYPO:0002506 name: abnormal protein palmitoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein palmitoylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0002503 ! abnormal protein palmitoylation created_by: midori creation_date: 2013-08-08T16:12:26Z [Term] id: FYPO:0002507 name: abolished protein palmitoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein palmitoylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein palmitoylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein palmitoylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002504 ! abolished protein palmitoylation is_a: FYPO:0002506 ! abnormal protein palmitoylation during vegetative growth created_by: midori creation_date: 2013-08-08T16:12:34Z [Term] id: FYPO:0002508 name: decreased protein palmitoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein palmitoylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein palmitoylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000545 ! decreased protein modification during vegetative growth is_a: FYPO:0002505 ! decreased protein palmitoylation is_a: FYPO:0002506 ! abnormal protein palmitoylation during vegetative growth created_by: midori creation_date: 2013-08-08T16:12:43Z [Term] id: FYPO:0002509 name: increased protein palmitoylation def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002499 ! increased protein modification is_a: FYPO:0002503 ! abnormal protein palmitoylation created_by: midori creation_date: 2013-08-08T16:21:52Z [Term] id: FYPO:0002510 name: increased protein palmitoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein palmitoylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification during vegetative growth is_a: FYPO:0002506 ! abnormal protein palmitoylation during vegetative growth is_a: FYPO:0002509 ! increased protein palmitoylation created_by: midori creation_date: 2013-08-08T16:22:35Z [Term] id: FYPO:0002511 name: abolished protein palmitoylation during meiosis def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein palmitoylation during meiotic nuclear division" EXACT [PomBase:mah] synonym: "protein palmitoylation abolished during meiosis" EXACT [PomBase:mah] synonym: "protein palmitoylation absent during meiosis" EXACT [PomBase:al] is_a: FYPO:0002504 ! abolished protein palmitoylation is_a: FYPO:0002514 ! abnormal protein palmitoylation during meiosis created_by: midori creation_date: 2013-08-08T16:24:46Z [Term] id: FYPO:0002512 name: decreased protein palmitoylation during meiosis def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein palmitoylation during meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein palmitoylation during meiosis" EXACT [PomBase:mah] is_a: FYPO:0002505 ! decreased protein palmitoylation is_a: FYPO:0002514 ! abnormal protein palmitoylation during meiosis created_by: midori creation_date: 2013-08-08T16:25:18Z [Term] id: FYPO:0002513 name: increased protein palmitoylation during meiosis def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein palmitoylation during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002509 ! increased protein palmitoylation is_a: FYPO:0002514 ! abnormal protein palmitoylation during meiosis created_by: midori creation_date: 2013-08-08T16:45:45Z [Term] id: FYPO:0002514 name: abnormal protein palmitoylation during meiosis def: "A cellular process phenotype in which the palmitoylation of one or more specific proteins is abnormal during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein palmitoylation during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002503 ! abnormal protein palmitoylation is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: midori creation_date: 2013-08-08T16:46:03Z [Term] id: FYPO:0002515 name: inviable after spore germination, without cell division, with branched, elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated, branched germ tube, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination, without cell division, branched, elongated cell" EXACT [PomBase:mah] synonym: "inviable following spore germination with elongated, branched germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with elongated, branched germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with branched, elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube is_a: FYPO:0002462 ! inviable branched, elongated vegetative cell created_by: midori creation_date: 2013-08-15T12:05:24Z [Term] id: FYPO:0002516 name: premature mitotic G2/M phase transition def: "A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins earlier than normal. The duration of G2 phase is thus shorter than normal. The mitotic G2/M transition is the point at which a cell commits to entering M phase, and begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed." [GO:0000086, PomBase:mah] comment: Use this term if you have measured CDK activity or calculated the transition point to detect the transition; otherwise, consider using 'premature mitosis' (FYPO:0001046). A G2/M advance may indicate that a checkpoint, such as the DNA replication checkpoint or the G2/M DNA damage checkpoint, is impaired. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "advanced mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "advanced mitotic G2/M transition" EXACT [PomBase:mah] synonym: "cell cycle, mitotic G2 advance" RELATED [PomBase:mah] synonym: "decreased duration of mitotic G2 phase" RELATED [PomBase:mah] synonym: "decreased duration of mitotic G2 phase during vegetative growth" RELATED [PomBase:mah] synonym: "decreased mitotic G2 duration" RELATED [PomBase:mah] synonym: "increased rate of mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "mitotic cell cycle advance at G2/M transition" EXACT [PomBase:mah] synonym: "mitotic G2 advance" RELATED [PomBase:mah] synonym: "mitotic G2/M transition advance" EXACT [PomBase:mah] synonym: "mitotic G2/M transition advance during vegetative growth" EXACT [PomBase:mah] synonym: "premature cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "premature G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic G2/M transition" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal mitotic G2/M phase transition is_a: FYPO:0000563 ! abnormal mitotic G2 phase progression is_a: FYPO:0000827 ! premature cell cycle phase transition relationship: has_output FYPO:0001046 ! premature mitosis created_by: midori creation_date: 2013-08-15T14:12:36Z [Term] id: FYPO:0002517 name: abnormal response to mitotic cell cycle checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle checkpoint signaling is abnormal (does not occur, or occurs abnormally). Abnormal arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal." [PomBase:mah] synonym: "abnormal mitotic cell cycle checkpoint arrest" RELATED [PomBase:mah] synonym: "abnormal occurrence of mitotic cell cycle arrest resulting from checkpoint activation" RELATED [PomBase:mah] synonym: "abnormal occurrence of mitotic cell cycle arrest resulting from defective checkpoint activation" RELATED [PomBase:vw] is_a: FYPO:0000011 ! abnormal cell cycle is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: has_output FYPO:0001026 ! abnormal occurrence of normal mitotic cell cycle arrest created_by: midori creation_date: 2013-08-15T14:28:54Z [Term] id: FYPO:0002518 name: abolished response to mitotic cell cycle checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal." [PomBase:mah] comment: May indicate that a cell cycle checkpoint is not activated under conditions that normally trigger checkpoint signaling and subsequent cell cycle arrest. synonym: "abolished cell cycle checkpoint arrest" RELATED [PomBase:mah] synonym: "cell cycle arrest resulting from mitotic cell cycle checkpoint activation abolished" EXACT [GO:0072414] is_a: FYPO:0002517 ! abnormal response to mitotic cell cycle checkpoint signaling relationship: has_output FYPO:0000827 ! premature cell cycle phase transition created_by: midori creation_date: 2013-08-15T14:45:22Z [Term] id: FYPO:0002519 name: abolished response to mitotic G2/M transition checkpoint signaling def: "A cellular process phenotype in which a cell cycle arrest that normally occurs in response to mitotic G2/M transition cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal." [PomBase:mah] comment: May indicate that a checkpoint, such as the DNA replication checkpoint or the G2/M DNA damage checkpoint, is not activated under conditions that normally trigger checkpoint signaling and subsequent cell cycle arrest. synonym: "abolished mitotic G2/M transition arrest" RELATED [PomBase:mah] synonym: "cell cycle arrest resulting from mitotic G2/M transition checkpoint activation abolished" EXACT [PomBase:mah] synonym: "mitotic G2/M checkpoint arrest deficient" RELATED [PomBase:vw] is_a: FYPO:0002518 ! abolished response to mitotic cell cycle checkpoint signaling relationship: has_output FYPO:0002516 ! premature mitotic G2/M phase transition created_by: midori creation_date: 2013-08-15T14:49:04Z [Term] id: FYPO:0002520 name: decreased frequency of conjugation with h+ cells def: "A cell population phenotype in which a smaller than normal proportion of cells in the population undergoes conjugation with wild type h+ cells." [PomBase:mah] synonym: "decreased conjugation with WT h+ cells" EXACT [PomBase:vw] synonym: "decreased frequency of conjugation with h plus cells" EXACT [PomBase:mah] synonym: "decreased frequency of mating with h+ cells" EXACT [PomBase:mah] synonym: "reduced frequency of conjugation with h+ cells" EXACT [PomBase:mah] is_a: FYPO:0000303 ! decreased conjugation frequency created_by: midori creation_date: 2013-08-15T15:10:31Z [Term] id: FYPO:0002521 name: decreased frequency of conjugation with h- cells def: "A cell population phenotype in which a smaller than normal proportion of cells in the population undergoes conjugation with wild type h- cells." [PomBase:mah] synonym: "decreased conjugation with WT h- cells" EXACT [PomBase:vw] synonym: "decreased frequency of conjugation with h minus cells" EXACT [PomBase:mah] synonym: "decreased frequency of mating with h- cells" EXACT [PomBase:mah] synonym: "reduced frequency of conjugation with h- cells" EXACT [PomBase:mah] is_a: FYPO:0000303 ! decreased conjugation frequency created_by: midori creation_date: 2013-08-15T15:12:10Z [Term] id: FYPO:0002522 name: decreased poly(A)+ mRNA export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is decreased. Export of all polyadenylated mRNAs or a specific mRNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased poly(A)+ mRNA export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased poly(A)+ mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "decreased polyadenylated mRNA export from nucleus" EXACT [PomBase:mah] synonym: "reduced poly(A)+ mRNA export from nucleus" EXACT [PomBase:mah] is_a: FYPO:0000183 ! abnormal poly(A)+ mRNA export from nucleus is_a: FYPO:0000508 ! decreased nuclear export relationship: has_output FYPO:0003119 ! increased nuclear polyadenylated mRNA level during vegetative growth created_by: midori creation_date: 2013-08-15T15:14:49Z [Term] id: FYPO:0002523 name: abnormal NADPH-hemoprotein reductase activity def: "A molecular function phenotype in which the observed rate of NADPH-hemoprotein reductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-08-15T15:20:21Z [Term] id: FYPO:0002524 name: increased NADPH-hemoprotein reductase activity def: "A molecular function phenotype in which the observed rate of NADPH-hemoprotein reductase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002523 ! abnormal NADPH-hemoprotein reductase activity created_by: midori creation_date: 2013-08-15T15:20:39Z [Term] id: FYPO:0002525 name: normal chromosome morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of one or more chromosomes are normal." [PomBase:mah] comment: Note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. synonym: "normal chromosome morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromosome morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2013-08-15T15:22:34Z [Term] id: FYPO:0002526 name: sensitive to latrunculin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to latrunculin B. Cells stop growing (and may die) at a concentration of latrunculin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to latrunculin B" EXACT [PomBase:mah] synonym: "sensitive to LatB" EXACT [PomBase:mah] synonym: "sensitive to latrunculin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to latrunculin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-08-27T14:23:03Z [Term] id: FYPO:0002527 name: increased duration of protein localization to cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the cell division site for longer than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to cell division site" EXACT [PomBase:mah] synonym: "increased duration of protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein recruitment to cell division site" RELATED [PomBase:vw] synonym: "prolonged protein localization to cell division site" EXACT [PomBase:mah] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2013-08-27T14:26:10Z [Term] id: FYPO:0002528 name: decreased duration of protein localization to cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the cell division site for a shorter time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased duration of protein localisation to cell division site" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of protein recruitment to cell division site" RELATED [PomBase:vw] synonym: "reduced duration of protein localization to cell division site" EXACT [PomBase:mah] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2013-08-27T14:28:38Z [Term] id: FYPO:0002529 name: abnormal protein localization to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleoplasm and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleoplasm" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2013-08-27T14:47:17Z [Term] id: FYPO:0002530 name: decreased protein localization to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleoplasm" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleoplasm" EXACT [PomBase:mah] is_a: FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-08-27T14:49:32Z [Term] id: FYPO:0002531 name: abolished protein localization to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleoplasm abolished" EXACT [PomBase:mah] is_a: FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-08-27T14:49:53Z [Term] id: FYPO:0002532 name: delayed onset of protein localization to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm begins later than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to nucleoplasm" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to nucleoplasm" EXACT [PomBase:mah] is_a: FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-08-27T14:53:26Z [Term] id: FYPO:0002533 name: abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abnormal during a cellular response to hydrogen peroxide." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleoplasm and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-08-27T14:54:05Z [Term] id: FYPO:0002534 name: abolished protein localization to nucleoplasm during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleoplasm abolished during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0002531 ! abolished protein localization to nucleoplasm is_a: FYPO:0002533 ! abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide created_by: midori creation_date: 2013-08-27T14:54:27Z [Term] id: FYPO:0002535 name: decreased protein localization to nucleoplasm during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0002530 ! decreased protein localization to nucleoplasm is_a: FYPO:0002533 ! abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide created_by: midori creation_date: 2013-08-27T14:54:56Z [Term] id: FYPO:0002536 name: delayed onset of protein localization to nucleoplasm during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm begins later than normal during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to nucleoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during cellular response to H2O2" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to nucleoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0002532 ! delayed onset of protein localization to nucleoplasm is_a: FYPO:0002533 ! abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide is_a: FYPO:0003226 ! delayed onset of protein localization to mitotic spindle created_by: midori creation_date: 2013-08-27T14:55:11Z [Term] id: FYPO:0002537 name: abnormal protein localization to nucleoplasm during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abnormal during a cellular response to hydroxyurea." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleoplasm and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleoplasm during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during cellular response to HU" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nucleoplasm during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-08-27T14:59:53Z [Term] id: FYPO:0002538 name: abolished protein localization to nucleoplasm during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleoplasm during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during cellular response to HU" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleoplasm abolished during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002531 ! abolished protein localization to nucleoplasm is_a: FYPO:0002537 ! abnormal protein localization to nucleoplasm during cellular response to hydroxyurea created_by: midori creation_date: 2013-08-27T15:00:01Z [Term] id: FYPO:0002539 name: delayed onset of protein localization to nucleoplasm during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm begins later than normal during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to nucleoplasm during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during cellular response to HU" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to nucleoplasm during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to nucleoplasm during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002532 ! delayed onset of protein localization to nucleoplasm is_a: FYPO:0002537 ! abnormal protein localization to nucleoplasm during cellular response to hydroxyurea is_a: FYPO:0003226 ! delayed onset of protein localization to mitotic spindle created_by: midori creation_date: 2013-08-27T15:00:08Z [Term] id: FYPO:0002540 name: decreased protein localization to nucleoplasm during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleoplasm during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleoplasm during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002530 ! decreased protein localization to nucleoplasm is_a: FYPO:0002537 ! abnormal protein localization to nucleoplasm during cellular response to hydroxyurea created_by: midori creation_date: 2013-08-27T15:05:15Z [Term] id: FYPO:0002541 name: increased protein localization to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleoplasm" EXACT [PomBase:mah] synonym: "increased protein localization to nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-08-27T15:07:25Z [Term] id: FYPO:0002542 name: obsolete decreased protein threonine phosphorylation at Thr-Pro site during cellular response to hydrogen peroxide def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues N-terminal to proline residues (i.e. in Thr-Pro sequences) occurs to a lower extent than normal during a cellular response to hydrogen peroxide." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased protein threonine phosphorylation at Thr-Pro site during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation at Thr-Pro site during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein threonine phosphorylation at Thr-Pro site during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation at threonine-proline site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation at TP site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "reduced protein threonine phosphorylation at Thr-Pro site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002446 created_by: midori creation_date: 2013-08-27T15:19:31Z [Term] id: FYPO:0002543 name: obsolete decreased protein threonine phosphorylation at Thr-Pro site during cellular response to hydroxyurea def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues N-terminal to proline residues (i.e. in Thr-Pro sequences) occurs to a lower extent than normal during a cellular response to hydroxyurea." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased protein threonine phosphorylation at Thr-Pro site during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation at Thr-Pro site during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein threonine phosphorylation at Thr-Pro site during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation at threonine-proline site during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation at TP site during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "reduced protein threonine phosphorylation at Thr-Pro site during cellular response to hydroxyurea" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002098 created_by: midori creation_date: 2013-08-27T15:22:07Z [Term] id: FYPO:0002544 name: obsolete abolished protein serine phosphorylation at RxxS site during cellular response to hydrogen peroxide def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) does not occur during a cellular response to hydrogen peroxide." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein serine phosphorylation at Arg-X-X-Ser site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at arginine-X-X-serine site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at PAS site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at phospho-Akt site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein serine phosphorylation abolished at RxxS site during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0006232 created_by: midori creation_date: 2013-08-27T15:23:47Z [Term] id: FYPO:0002545 name: obsolete abolished protein serine phosphorylation at RxxS site during cellular response to hydroxyurea def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) does not occur during a cellular response to hydroxyurea." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein serine phosphorylation at Arg-X-X-Ser site during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at arginine-X-X-serine site during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at PAS site during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at phospho-Akt site during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during cellular response to HU" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "protein serine phosphorylation abolished at RxxS site during cellular response to hydroxyurea" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004550 created_by: midori creation_date: 2013-08-27T15:26:39Z [Term] id: FYPO:0002546 name: sensitive to trichostatin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trichostatin A. Cells stop growing (and may die) at a concentration of trichostatin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to trichostatin A" EXACT [PomBase:mah] synonym: "sensitive to trichostatin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to trichostatin A during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to TSA" EXACT [PMID:17004072] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-08-27T15:41:53Z [Term] id: FYPO:0002547 name: sensitive to nicotinamide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nicotinamide. Cells stop growing (and may die) at a concentration of nicotinamide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nicotinamide" EXACT [PomBase:mah] synonym: "sensitive to nicotinamide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nicotinamide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-08-27T15:42:25Z [Term] id: FYPO:0002548 name: increased cellular 4'-phosphopantothenate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4'-phosphopantothenate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased 4'-phosphopantothenate accumulation" RELATED [PomBase:mah] synonym: "increased cellular 4'-phosphopantothenate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 4'-phosphopantothenate level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-08-27T15:45:17Z [Term] id: FYPO:0002549 name: sensitive to stress def: "A phenotype in which cells in a population show increased sensitivity to a stress. Typically, a cell population is deemed sensitive to a stress if cells in the population stop growing (and may die) when exposed to the stress at an intensity that allows a population of wild type cells to grow and divide." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Use a descendant of this term if you have assayed growth of cells exposed to a stress in culture. If you have assayed the response to the stress at the subcellular or molecular level, consider annotating to a descendant of 'abnormal cellular response to stress' (FYPO:0000162). subset: qc_do_not_manually_annotate synonym: "decreased growth during cellular response to stress" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to stress" EXACT [PomBase:mah] synonym: "hypersensitive to stress" EXACT [PomBase:mah] synonym: "stress resistance: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000045 ! abnormal cell population growth created_by: midori creation_date: 2013-08-27T15:46:35Z [Term] id: FYPO:0002550 name: sensitive to UV def: "A cell phenotype in which cells show increased sensitivity to ultraviolet light." [PomBase:mah] synonym: "decreased cell population growth during cellular response to UV" EXACT [PomBase:mah] synonym: "decreased growth during cellular response to UV" EXACT [PomBase:mah] synonym: "hypersensitive to UV" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light" EXACT [PomBase:mah] synonym: "UV resistance: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002549 ! sensitive to stress created_by: midori creation_date: 2013-08-27T15:48:41Z [Term] id: FYPO:0002551 name: sensitive to UV during G0 def: "A cell phenotype in which cells show increased sensitivity to ultraviolet light during G0 phase." [PomBase:mah] synonym: "decreased cell population growth during cellular response to UV during G0" EXACT [PomBase:mah] synonym: "decreased growth during cellular response to UV during G0" EXACT [PomBase:mah] synonym: "hypersensitive to UV during G0" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation during G0" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light during G0" EXACT [PomBase:mah] synonym: "sensitive to UV during cell quiescence" EXACT [PomBase:mah] synonym: "sensitive to UV during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002550 ! sensitive to UV created_by: midori creation_date: 2013-08-27T15:50:17Z [Term] id: FYPO:0002552 name: lipid droplets present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer lipid droplets than normal." [PomBase:mah] synonym: "decreased level of lipid droplets" RELATED [PomBase:al] synonym: "fewer lipid droplets present during vegetative growth" EXACT [PomBase:mah] synonym: "lipid droplets present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lipid droplets present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "lipid droplets present in reduced numbers" EXACT [PomBase:mah] synonym: "lipid particles present in decreased numbers" EXACT [GO:0005811, PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2013-08-27T15:53:30Z [Term] id: FYPO:0002553 name: abnormal double-strand break processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing is abnormal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang." [GO:0000729, PomBase:mah] synonym: "abnormal double-strand break processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal double-strand break processing during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal DSB processing" EXACT [PomBase:vw] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2013-08-28T10:34:04Z [Term] id: FYPO:0002554 name: normal protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a region of a chromosome at which a DNA double-strand break has occurred is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "normal protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to DSB" EXACT [PomBase:vw] synonym: "normal protein localization to site of double-strand break" EXACT [PomBase:mah] synonym: "normal protein localization to site of DSB" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-08-28T10:40:47Z [Term] id: FYPO:0002555 name: abolished protein localization to medial cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortex during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "abolished protein localization to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] synonym: "protein localization to medial cortex abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000731 ! abnormal protein localization to medial cortex during vegetative growth is_a: FYPO:0001371 ! abolished protein localization to medial cortex created_by: midori creation_date: 2013-08-28T11:26:06Z [Term] id: FYPO:0002556 name: decreased protein localization to medial cortex, with protein distributed in cell cortex near non-growing end, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex of half of the cell nearer the non-growing end. There may be little or no protein detected at the medial cortex." [PomBase:al, PomBase:mah, PomBase:vw] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to medial cortex during vegetative growth, with protein distributed in cortex of non-growing half of cell" NARROW [PomBase:mah] synonym: "decreased protein localisation to medial cortex during vegetative growth, with protein distributed in cell cortex near non-growing end" EXACT [PomBase:mah] synonym: "decreased protein localization to medial cortex during vegetative growth, with protein distributed in cell cortex near non-growing end" EXACT [PomBase:mah] synonym: "decreased protein localization to medial cortex during vegetative growth, with protein distributed in cell cortex near non-growing end, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to medial cortex during vegetative growth, with protein distributed in cortex of non-growing half of cell" EXACT [PomBase:mah] synonym: "decreased protein localization to medial ring, with protein distributed in cell cortex near non-growing end, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to medial cortex during vegetative growth, with protein distributed in cell cortex near non-growing end" EXACT [PomBase:mah] is_a: FYPO:0006638 ! decreased protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth created_by: midori creation_date: 2013-08-28T11:29:01Z [Term] id: FYPO:0002557 name: decreased protein localization to medial cortex during vegetative growth def: "A cell phenotype in which the localization of a protein to the medial cortex is decreased in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to medial cortex during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "decreased protein localization to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] synonym: "reduced protein localization to medial cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000731 ! abnormal protein localization to medial cortex during vegetative growth created_by: midori creation_date: 2013-08-28T11:31:22Z [Term] id: FYPO:0002558 name: normal protein localization to medial cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to medial cortex during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-08-28T11:32:40Z [Term] id: FYPO:0002559 name: normal protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "normal protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "normal protein localization to contractile ring" EXACT [PomBase:al] synonym: "normal protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "normal protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "normal protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-08-28T11:41:22Z [Term] id: FYPO:0002560 name: abnormal protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the centromere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "abnormal protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "abnormal protein localization to contractile ring" EXACT [PomBase:al] synonym: "abnormal protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "abnormal protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "abnormal protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2013-08-28T11:43:36Z [Term] id: FYPO:0002561 name: abolished protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "abolished protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "abolished protein localization to contractile ring" EXACT [PomBase:al] synonym: "abolished protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "abolished protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "abolished protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "protein localization to actomyosin contractile ring abolished" EXACT [PomBase:mah] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2013-08-28T11:43:43Z [Term] id: FYPO:0002562 name: delayed onset of protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring begins later than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "delayed onset of protein localization to contractile ring" EXACT [PomBase:al] synonym: "delayed onset of protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "delayed onset of protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "delayed onset of protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "delayed protein localization to actomyosin contractile ring" EXACT [PomBase:mah] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2013-08-28T11:44:12Z [Term] id: FYPO:0002563 name: normal protein localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "normal protein localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-08-28T11:48:40Z [Term] id: FYPO:0002564 name: increased mature tRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is higher than normal. Total tRNA or a specific tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mature transfer RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature tRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased mature tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature tRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "increased tRNA level during vegetative growth" BROAD [SO:0000253] is_a: FYPO:0002579 ! altered mature tRNA level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2013-08-28T13:48:20Z [Term] id: FYPO:0002565 name: abolished histone methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation does not occur. All histone methylation may be affected, or methylation of specific sites on specific histones may be abolished." [PomBase:mah] synonym: "abolished histone methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "histone methylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone methylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth is_a: FYPO:0000544 ! abolished protein modification during vegetative growth created_by: midori creation_date: 2013-08-28T13:54:16Z [Term] id: FYPO:0002566 name: abolished histone H3-K9 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished histone H3-K9 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K9me during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished histone lysine H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "histone H3-K9 methylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 methylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation during vegetative growth is_a: FYPO:0002565 ! abolished histone methylation during vegetative growth created_by: midori creation_date: 2013-08-28T13:56:00Z [Term] id: FYPO:0002567 name: normal centromeric outer repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNAs transcribed from the centromere outer repeat region measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term encompasses both unprocessed RNA transcribed from the centromere outer repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. synonym: "normal accumulation of centromeric outer repeat transcripts" RELATED [PomBase:mah] synonym: "normal accumulation of centromeric outer repeat transcripts during vegetative growth" EXACT [PomBase:mah] synonym: "normal accumulation of non-coding outer repeat transcripts" EXACT [PomBase:vw] synonym: "normal centromeric outer repeat transcript accumulation" RELATED [PomBase:mah] synonym: "normal centromeric outer repeat transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal centromeric outer repeat transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of centromeric outer repeat transcripts" EXACT [PomBase:al] is_a: FYPO:0008177 ! normal centromeric RNA level during vegetative growth created_by: midori creation_date: 2013-08-28T14:38:37Z [Term] id: FYPO:0002568 name: abolished protein localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "abolished protein localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nuclear periphery abolished" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth is_a: FYPO:0002338 ! abnormal protein localization to nuclear periphery created_by: midori creation_date: 2013-08-28T14:45:05Z [Term] id: FYPO:0002569 name: increased cellular dCTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dCTP measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dCTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular dCTP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased dCTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-08-28T14:52:37Z [Term] id: FYPO:0002570 name: increased cellular dATP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dATP measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dATP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular dATP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased dATP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-08-28T14:53:33Z [Term] id: FYPO:0002571 name: decreased cellular dGTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dGTP measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular dGTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular dGTP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular dGTP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-08-28T14:54:51Z [Term] id: FYPO:0002572 name: decreased cellular dTTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTTP measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular dTTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular dTTP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular dTTP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-08-28T14:56:01Z [Term] id: FYPO:0002573 name: increased number of Ssb1 foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Ssb1 accumulates is greater than normal." [PMID:22927644, PomBase:mah] synonym: "increased number of Rad11 foci" EXACT [PMID:22927644] synonym: "increased number of RPA foci" EXACT [PMID:22927644] synonym: "increased number of Rpa1 foci" EXACT [PMID:22927644] synonym: "increased number of Ssb1 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Ssb1 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2013-08-28T15:01:41Z [Term] id: FYPO:0002574 name: normal protein localization to centromere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localisation to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "normal protein localization to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromosome, centric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "normal protein localization to chromosome, centromeric region during vegetative growth" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0007853 ! normal protein localization to centromere created_by: midori creation_date: 2013-08-28T15:10:06Z [Term] id: FYPO:0002575 name: normal protein localization to chromosome at long terminal repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein a region in a chromosome that contains one or more long terminal repeats (LTRs) is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromosome at long terminal repeat" EXACT [PomBase:mah] synonym: "normal protein localization to chromosome at long terminal repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromosome at long terminal repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromosome at LTR" EXACT [PomBase:mah] synonym: "normal protein localization to LTR" EXACT [PomBase:al] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0004997 ! normal protein localization to chromosome created_by: midori creation_date: 2013-08-28T15:14:19Z [Term] id: FYPO:0002576 name: abnormal chromatin binding def: "A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds chromatin differently from wild type, or that a mutation in one gene affects chromatin binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2013-08-28T15:21:27Z [Term] id: FYPO:0002577 name: decreased chromatin binding def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "reduced chromatin binding" EXACT [PomBase:mah] is_a: FYPO:0002576 ! abnormal chromatin binding created_by: midori creation_date: 2013-08-28T15:21:38Z [Term] id: FYPO:0002578 name: resistance to hydroxyurea def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hydroxyurea than normal." [PomBase:mah] synonym: "resistance to HU" EXACT [PomBase:mah] synonym: "resistance to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-08-28T15:27:26Z [Term] id: FYPO:0002579 name: altered mature tRNA level during vegetative growth def: "A cell phenotype in which the amount of mature transfer RNA (tRNA) measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total tRNA or a specific tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal tRNA level during vegetative growth" BROAD [PomBase:mah] synonym: "altered cellular mature tRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered mature cellular transfer RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered mature tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered mature tRNA transcript level during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0008101 ! altered tRNA or precursor level during vegetative growth created_by: midori creation_date: 2013-08-28T16:07:23Z [Term] id: FYPO:0002580 name: normal mature tRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total tRNA or a specific tRNA may be measured." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mature transfer RNA level" EXACT [PomBase:mah] synonym: "normal mature tRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature tRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature tRNA transcript level" EXACT [PomBase:mah] synonym: "normal tRNA level" BROAD [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2013-08-28T16:11:10Z [Term] id: FYPO:0002581 name: increased level of nuclear tRNA processing intermediates with 3' extensions def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any tRNA processing intermediates with 3' extensions measured in the nucleus is higher than normal." [PomBase:mah] synonym: "increased accumulation of nuclear tRNA processing intermediates with 3' extensions" RELATED [PomBase:al] synonym: "increased level of nuclear tRNA processing intermediates with 3' extensions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of nuclear tRNA processing intermediates with 3' extensions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008101 ! altered tRNA or precursor level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2013-08-28T16:12:36Z [Term] id: FYPO:0002582 name: normal mature mitochondrial tRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature mitochondrial transfer RNA (tRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total tRNA or a specific tRNA may be measured." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mature mitochondrial transfer RNA level" EXACT [PomBase:mah] synonym: "normal mature mitochondrial tRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature mitochondrial tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature mitochondrial tRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature mitochondrial tRNA transcript level" EXACT [PomBase:mah] synonym: "normal mitochondrial tRNA level" BROAD [PomBase:mah] is_a: FYPO:0002580 ! normal mature tRNA level is_a: FYPO:0004960 ! normal mitochondrial RNA level created_by: midori creation_date: 2013-08-28T16:18:45Z [Term] id: FYPO:0002583 name: decreased mature tRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is lower than normal. Total tRNA or a specific tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature transfer RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature tRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased mature tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature tRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "decreased tRNA level during vegetative growth" BROAD [PomBase:mah] synonym: "reduced mature tRNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002579 ! altered mature tRNA level during vegetative growth is_a: FYPO:0008342 ! decreased pre-tRNA or mature level during vegetative growth created_by: midori creation_date: 2013-08-28T16:20:19Z [Term] id: FYPO:0002584 name: decreased mature mitochondrial tRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature mitochondrial transfer RNA (tRNA) measured in a cell is lower than normal. Total tRNA or a specific tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature mitochondrial transfer RNA level" EXACT [PomBase:mah] synonym: "decreased mature mitochondrial tRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature mitochondrial tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature mitochondrial tRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature mitochondrial tRNA transcript level" EXACT [PomBase:vw] synonym: "decreased mitochondrial tRNA level" BROAD [PomBase:mah] synonym: "reduced mitochondrial tRNA level" EXACT [PomBase:mah] is_a: FYPO:0002583 ! decreased mature tRNA level during vegetative growth is_a: FYPO:0003423 ! decreased mitochondrial RNA level created_by: midori creation_date: 2013-08-28T16:22:12Z [Term] id: FYPO:0002585 name: mature mitochondrial tRNA absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature mitochondrial transfer RNA (tRNA) measured in a cell is too low to detect. Total tRNA or a specific tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "mature mitochondrial transfer RNA absent from cell" EXACT [PomBase:mah] synonym: "mature mitochondrial tRNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mature mitochondrial tRNA absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "mature mitochondrial tRNA transcripts absent from cell" EXACT [PomBase:vw] synonym: "mitochondrial tRNA absent from cell" BROAD [PomBase:mah] synonym: "undetectable mature mitochondrial tRNA level" EXACT [PomBase:mah] is_a: FYPO:0002584 ! decreased mature mitochondrial tRNA level is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: midori creation_date: 2013-08-28T16:24:01Z [Term] id: FYPO:0002586 name: normal mitochondrial tRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial tRNA 3'-end processing is normal (i.e. indistinguishable from wild type). In mitochondrial tRNA 3'-end processing, the 3' end of a mitochondrial pre-tRNA molecule is converted to that of a mature mitochondrial tRNA." [GO:0006396, PomBase:mah] synonym: "normal mitochondrial transfer RNA 3'-end processing" EXACT [PomBase:mah] synonym: "normal mitochondrial tRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial tRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process during vegetative growth created_by: midori creation_date: 2013-08-28T16:27:04Z [Term] id: FYPO:0002587 name: increased level of mitochondrial polycistronic RNA precursors def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any mitochondrially-encoded polycistronic RNA precursors measured in the cell is higher than normal." [PomBase:mah] synonym: "increased accumulation of mitochondrial polycistronic RNA precursors" RELATED [PomBase:al] synonym: "increased level of mitochondrial polycistronic RNA precursors during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of mitochondrial polycistronic RNA precursors during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-08-28T16:30:56Z [Term] id: FYPO:0002588 name: resistance to nickel def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nickel ions than normal." [PomBase:mah] synonym: "resistance to nickel during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to nickel during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to nickel ion" EXACT [PomBase:mah] synonym: "resistance to nickel ions" EXACT [PomBase:mah] synonym: "resistant to nickel" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-08-28T16:35:20Z [Term] id: FYPO:0002589 name: resistance to zinc def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of zinc ions than normal." [PomBase:mah] synonym: "resistance to zinc during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to zinc during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to zinc ion" EXACT [PomBase:mah] synonym: "resistance to zinc ions" EXACT [PomBase:mah] synonym: "resistant to zinc" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-08-28T16:35:56Z [Term] id: FYPO:0002590 name: increased level of mitochondrial tRNA processing intermediates with 3' extensions def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any tRNA processing intermediates with 3' extensions measured in the mitochondria is higher than normal." [PomBase:mah] synonym: "increased accumulation of mitochondrial tRNA processing intermediates with 3' extensions" RELATED [PomBase:al] synonym: "increased level of mitochondrial tRNA processing intermediates with 3' extensions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of mitochondrial tRNA processing intermediates with 3' extensions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008101 ! altered tRNA or precursor level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2013-08-29T16:55:19Z [Term] id: FYPO:0002591 name: abnormal histone phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation is abnormal. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be altered." [PomBase:mah] synonym: "abnormal histone phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification during vegetative growth created_by: midori creation_date: 2013-09-04T16:01:06Z [Term] id: FYPO:0002592 name: abolished histone phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation does not occur. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be abolished." [PomBase:mah] synonym: "abolished histone phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "histone phosphorylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone phosphorylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:01:32Z [Term] id: FYPO:0002593 name: decreased histone phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation occurs to a lower extent than normal. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be decreased." [PomBase:mah] synonym: "decreased histone phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:01:46Z [Term] id: FYPO:0002594 name: increased histone phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation occurs to a greater extent than normal. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be increased." [PomBase:mah] synonym: "increased histone phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:01:59Z [Term] id: FYPO:0002595 name: normal histone phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation is normal. All histone phosphorylation may be assayed, or phosphorylation of specific sites on specific histones may be measured." [PomBase:mah] synonym: "normal histone phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002600 ! normal histone modification during vegetative growth created_by: midori creation_date: 2013-09-04T16:02:14Z [Term] id: FYPO:0002596 name: increased histone H2A phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:18:17Z [Term] id: FYPO:0002597 name: abolished histone H2A phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation does not occur. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished histone H2A phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "histone H2A phosphorylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H2A phosphorylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth is_a: FYPO:0002599 ! abnormal histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:18:17Z [Term] id: FYPO:0002598 name: decreased histone H2A phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:mah] synonym: "decreased histone H2A phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone H2A phosphorylation" EXACT [PomBase:mah] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:18:17Z [Term] id: FYPO:0002599 name: abnormal histone H2A phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is abnormal. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be altered." [PomBase:mah] synonym: "abnormal histone H2A phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification during vegetative growth created_by: midori creation_date: 2013-09-04T16:18:17Z [Term] id: FYPO:0002600 name: normal histone modification during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone modification is normal. All histone modification may be assayed, or modification of specific sites on specific histones may be measured." [PomBase:mah] synonym: "normal histone modification during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2013-09-04T16:18:49Z [Term] id: FYPO:0002601 name: normal histone H2A phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured." [PomBase:mah] synonym: "normal histone H2A phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002595 ! normal histone phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:19:00Z [Term] id: FYPO:0002602 name: decreased histone H2A phosphorylation during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:mah] synonym: "decreased histone H2A phosphorylation during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H2A phosphorylation during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:36:11Z [Term] id: FYPO:0002603 name: abolished histone H2A phosphorylation at mating type locus during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation does not occur at the mating type locus during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be abolished." [PomBase:mah] synonym: "abolished histone H2A phosphorylation at mating type locus during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H2A phosphorylation at mating type region during mitotic S phase" EXACT [PomBase:mah, SO:0001789] synonym: "histone H2A phosphorylation abolished at mating type locus during mitotic S phase" EXACT [PomBase:mah] synonym: "histone H2A phosphorylation absent at mating type locus during mitotic S phase" EXACT [PomBase:al] is_a: FYPO:0002597 ! abolished histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:37:06Z [Term] id: FYPO:0002604 name: increased histone H2A phosphorylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at ribosomal DNA. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H2A phosphorylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T16:38:42Z [Term] id: FYPO:0002605 name: increased histone H2A phosphorylation at rDNA during mitotic G2 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at ribosomal DNA during G2 phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation at rDNA during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation at ribosomal DNA during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0002604 ! increased histone H2A phosphorylation at rDNA during vegetative growth is_a: FYPO:0004112 ! increased protein phosphorylation during mitotic G2 phase created_by: midori creation_date: 2013-09-04T16:57:55Z [Term] id: FYPO:0002606 name: increased histone H2A phosphorylation at rDNA during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at ribosomal DNA during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation at rDNA during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation at ribosomal DNA during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0002604 ! increased histone H2A phosphorylation at rDNA during vegetative growth is_a: FYPO:0004353 ! increased protein phosphorylation during mitotic S phase created_by: midori creation_date: 2013-09-04T17:02:48Z [Term] id: FYPO:0002607 name: increased histone H2A phosphorylation at centromeric tDNA during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at tRNA genes (tDNA) in centromeric regions during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation at centromeric tDNA during mitotic S phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:03:08Z [Term] id: FYPO:0002608 name: increased histone H2A phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal during a cellular response to hydroxyurea. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H2A phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:03:47Z [Term] id: FYPO:0002609 name: decreased histone H2A phosphorylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal at centromeric outer repeat regions. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:mah] synonym: "decreased histone H2A phosphorylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H2A phosphorylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H2A phosphorylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H2A phosphorylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H2A phosphorylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "reduced histone H2A phosphorylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:04:16Z [Term] id: FYPO:0002610 name: normal histone H2A phosphorylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at centromeric outer repeat regions. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured." [PomBase:mah] synonym: "abnormal histone H2A phosphorylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H2A phosphorylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H2A phosphorylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H2A phosphorylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H2A phosphorylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002601 ! normal histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:04:50Z [Term] id: FYPO:0002611 name: decreased histone H2A phosphorylation at subtelomeric heterochromatin during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal at subtelomeric regions during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:mah] synonym: "decreased histone H2A phosphorylation at subtelomere during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased histone H2A phosphorylation at subtelomeric heterochromatin during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H2A phosphorylation at subtelomeric heterochromatin during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:12:50Z [Term] id: FYPO:0002612 name: normal histone H2A phosphorylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at subtelomeric regions. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured." [PomBase:mah] synonym: "normal histone H2A phosphorylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H2A phosphorylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002601 ! normal histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:13:15Z [Term] id: FYPO:0002613 name: normal histone H2A phosphorylation at mating type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at the mating type locus. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured." [PomBase:mah] synonym: "normal histone H2A phosphorylation at mating type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H2A phosphorylation at mating type region during vegetative growth" EXACT [PomBase:mah, SO:0001789] is_a: FYPO:0002601 ! normal histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-04T17:13:15Z [Term] id: FYPO:0002614 name: abnormal protein localization to pre-autophagosomal structure def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the pre-autophagosomal structure and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to PAS" EXACT [GO:0034497, PomBase:mah] synonym: "abnormal protein localisation to pre-autophagosomal structure" EXACT [PomBase:mah] synonym: "abnormal protein localization to pre-autophagosomal structure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to pre-autophagosomal structure during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2013-09-05T14:45:24Z [Term] id: FYPO:0002615 name: decreased protein localization to pre-autophagosomal structure def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to pre-autophagosomal structure" EXACT [PomBase:mah] synonym: "decreased protein localization to PAS" EXACT [GO:0034497, PomBase:mah] synonym: "decreased protein localization to pre-autophagosomal structure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to pre-autophagosomal structure during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to pre-autophagosomal structure" EXACT [PomBase:mah] is_a: FYPO:0002614 ! abnormal protein localization to pre-autophagosomal structure created_by: midori creation_date: 2013-09-05T14:45:34Z [Term] id: FYPO:0002616 name: increased protein localization to pre-autophagosomal structure def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to pre-autophagosomal structure" EXACT [PomBase:mah] synonym: "increased protein localization to PAS" EXACT [GO:0034497, PomBase:mah] synonym: "increased protein localization to pre-autophagosomal structure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to pre-autophagosomal structure during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002614 ! abnormal protein localization to pre-autophagosomal structure created_by: midori creation_date: 2013-09-05T14:45:51Z [Term] id: FYPO:0002617 name: sensitive to sodium butyrate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium butyrate. Cells stop growing (and may die) at a concentration of sodium butyrate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium butyrate" EXACT [PomBase:mah] synonym: "sensitive to sodium butyrate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium butyrate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-05T15:14:13Z [Term] id: FYPO:0002618 name: normal growth on valproic acid def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing valproic acid." [PomBase:mah] synonym: "normal cell population growth in presence of valproic acid" EXACT [PomBase:mah] synonym: "normal cell population growth on valproic acid" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to valproic acid" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on valproic acid" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-05T15:31:40Z [Term] id: FYPO:0002619 name: normal growth on sodium butyrate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium butyrate." [PomBase:mah] synonym: "normal cell population growth in presence of sodium butyrate" EXACT [PomBase:mah] synonym: "normal cell population growth on sodium butyrate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to sodium butyrate" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on sodium butyrate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-05T15:33:22Z [Term] id: FYPO:0002620 name: normal growth on trichostatin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trichostatin A." [PomBase:mah] synonym: "normal cell population growth in presence of trichostatin A" EXACT [PomBase:mah] synonym: "normal cell population growth on trichostatin A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to trichostatin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on trichostatin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-05T15:34:29Z [Term] id: FYPO:0002621 name: abnormal malate dehydrogenase (decarboxylating) (NAD+) activity def: "A molecular function phenotype in which the observed rate of malate dehydrogenase (decarboxylating) (NAD+) activity is abnormal." [PomBase:mah] synonym: "abnormal 'malic' enzyme activity" RELATED [GO:0004471] synonym: "abnormal (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "abnormal malate dehydrogenase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "abnormal NAD-linked malic enzyme activity" RELATED [GO:0004471] synonym: "abnormal NAD-malic enzyme activity" BROAD [GO:0004471] synonym: "abnormal NAD-specific malic enzyme activity" RELATED [GO:0004471] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-09-05T15:47:08Z [Term] id: FYPO:0002622 name: decreased malate dehydrogenase (decarboxylating) (NAD+) activity def: "A molecular function phenotype in which the observed rate of malate dehydrogenase (decarboxylating) (NAD+) activity is decreased." [PomBase:mah] synonym: "decreased 'malic' enzyme activity" RELATED [GO:0004471] synonym: "decreased (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "decreased malate dehydrogenase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "decreased NAD-linked malic enzyme activity" RELATED [GO:0004471] synonym: "decreased NAD-malic enzyme activity" BROAD [GO:0004471] synonym: "decreased NAD-specific malic enzyme activity" RELATED [GO:0004471] synonym: "reduced malate dehydrogenase (decarboxylating) (NAD+) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002621 ! abnormal malate dehydrogenase (decarboxylating) (NAD+) activity created_by: midori creation_date: 2013-09-05T15:47:25Z [Term] id: FYPO:0002623 name: decreased RNA level during cellular response to glucose stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to a glucose stimulus is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to glucose stimulus" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to glucose stimulus" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to glucose" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to glucose stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to glucose stimulus during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to glucose stimulus" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to glucose stimulus" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-09-05T15:50:26Z [Term] id: FYPO:0002624 name: decreased punctate nuclear protein localization def: "A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that fewer dots are observed than in normal (wild type) cells." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased punctate nuclear protein localisation" EXACT [PomBase:mah] synonym: "decreased punctate nuclear protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased punctate nuclear protein localization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced punctate nuclear protein localization" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2013-09-05T16:01:22Z [Term] id: FYPO:0002625 name: normal protein localization to chromatin rDNA def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to parts of the chromosome containing ribosomal DNA is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to rDNA" EXACT [PomBase:mah] synonym: "normal protein localization to rDNA" RELATED [] synonym: "normal protein localization to rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to ribosomal DNA" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-09-05T16:03:48Z [Term] id: FYPO:0002626 name: resistance to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to heat." [PomBase:mah] comment: For fission yeast, high temperature usually corresponds to above 32 degrees Celsius. Use this term if you have assayed growth of cells exposed to heat in culture. If you have assayed the response to heat at the subcellular or molecular level, consider annotating to 'abnormal cellular response to heat' (FYPO:0000212). synonym: "heat resistance" EXACT [PomBase:mah] synonym: "increased growth during cellular response to heat" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to heat" EXACT [PomBase:mah] synonym: "resistance to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to heat during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to high temperature" EXACT [PomBase:al] synonym: "resistant to heat" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2013-09-05T16:10:37Z [Term] id: FYPO:0002627 name: altered level of substance in cell wall during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cell wall differs from normal." [PomBase:mah] synonym: "abnormal level of substance in cell wall during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of substance in cell wall during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth is_a: FYPO:0007492 ! altered level of substance in cell wall created_by: midori creation_date: 2013-09-05T16:37:47Z [Term] id: FYPO:0002628 name: decreased level of substance in cell wall during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased level of substance in cell wall during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced level of substance in cell wall during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0002627 ! altered level of substance in cell wall during vegetative growth created_by: midori creation_date: 2013-09-05T16:41:13Z [Term] id: FYPO:0002629 name: galactose absent from cell wall def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactose measured in the cell wall is too low to detect." [PomBase:mah] comment: Note that 'galactose absent from cell wall glycoprotein glycan' (FYPO:0003727) is not a child of this term because the cell wall may contain galactose residues in glycans that are not part of glycosylated proteins. synonym: "galactose absent from cell surface" RELATED [PomBase:al] synonym: "galactose absent from cell wall during mitotic cell cycle" RELATED [PomBase:mah] synonym: "galactose absent from cell wall during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0002628 ! decreased level of substance in cell wall during vegetative growth created_by: midori creation_date: 2013-09-05T16:54:57Z [Term] id: FYPO:0002630 name: irregular cell wall during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the outer surface of the fungal-type cell wall is rougher and less regular than normal." [PomBase:al, PomBase:mah] synonym: "irregular cell wall during mitotic cell cycle" RELATED [PomBase:mah] synonym: "irregular cell wall surface texture during vegetative growth" EXACT [PATO:0000700, PomBase:mah] synonym: "rough cell wall during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000351 ! abnormal cell wall morphology during vegetative growth created_by: midori creation_date: 2013-09-05T17:07:11Z [Term] id: FYPO:0002631 name: abnormal dTTP biosynthetic process def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which dTTP biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal dTTP biosynthesis" EXACT [GO:0006235, PomBase:mah] synonym: "abnormal dTTP biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal dTTP biosynthetic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2013-09-05T17:18:46Z [Term] id: FYPO:0002632 name: decreased dTTP biosynthetic process def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which dTTP biosynthesis is decreased." [PomBase:mah] synonym: "decreased dTTP biosynthesis" EXACT [GO:0006235, PomBase:mah] synonym: "decreased dTTP biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased dTTP biosynthetic process during vegetative growth" EXACT [PomBase:mah] synonym: "reduced dTTP biosynthetic process" EXACT [PomBase:mah] is_a: FYPO:0002631 ! abnormal dTTP biosynthetic process created_by: midori creation_date: 2013-09-05T17:18:50Z [Term] id: FYPO:0002633 name: increased cellular dTTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTTP measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dTTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular dTTP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased dTTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-09-05T17:21:44Z [Term] id: FYPO:0002634 name: resistance to cobalt def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cobalt ions than normal." [PomBase:mah] synonym: "resistance to cobalt during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cobalt during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to cobalt ion" EXACT [PomBase:mah] synonym: "resistance to cobalt ions" EXACT [PomBase:mah] synonym: "resistant to cobalt" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-09-06T16:22:20Z [Term] id: FYPO:0002635 name: normal protein ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein ubiquitinylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein ubiquitylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein/peptide ubiquitination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2013-09-11T13:01:58Z [Term] id: FYPO:0002636 name: delayed onset of mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation begins later than normal." [PomBase:mah] synonym: "delayed mitotic spindle elongation" EXACT [PomBase:mah] synonym: "delayed onset of mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic spindle elongation delayed" EXACT [PomBase:vw] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation created_by: midori creation_date: 2013-09-11T13:43:06Z [Term] id: FYPO:0002637 name: normal growth on hygromycin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hygromycin B." [PomBase:mah] synonym: "normal cell population growth in presence of hygromycin B" EXACT [PomBase:mah] synonym: "normal cell population growth on hygromycin B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on hygromycin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-11T14:14:32Z [Term] id: FYPO:0002638 name: increased activation of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the mitotic spindle assembly checkpoint is activated more frequently than normal, typically under conditions that do not cause checkpoint activation in wild-type cells. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PomBase:mah, PomBase:vw] comment: Checkpoint activation in a mutant usually implies that the mutation is causing problems that the checkpoint detects. synonym: "activation of mitotic spindle assembly checkpoint increased" EXACT [PomBase:mah] synonym: "increased activation of mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "increased Bub1 foci" RELATED [PomBane:vw] synonym: "increased Mad2 foci" RELATED [PomBase:vw] synonym: "increased mitotic cell cycle spindle assembly checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint created_by: midori creation_date: 2013-09-11T14:32:46Z [Term] id: FYPO:0002639 name: increased interkinetochore distance before mitotic anaphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between sister kinetochores is greater than normal before the onset of mitotic anaphase." [PMID:22065639, PomBase:mah] comment: Use this term in cases where "stretching" refers to the distance between sister kinetochores of duplicated chromosomes that are bioriented on the spindle during mitosis. Also see 'abnormal kinetochore localization' (FYPO:0001778) and 'abnormal mitotic sister chromatid segregation' (FYPO:0000141). synonym: "increased distance between mitotic kinetochores" RELATED [PomBase:vw] synonym: "increased interkinetochore distance before anaphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased interkinetochore distance before anaphase onset" EXACT [PMID:22065639] synonym: "increased interkinetochore distance before mitotic anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased kinetochore stretching before mitotic anaphase" RELATED [PomBase:mah] synonym: "increased sister kinetochore distance before mitotic anaphase" EXACT [PMID:22065639, PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0001778 ! abnormal centromere localization created_by: midori creation_date: 2013-09-11T15:30:13Z [Term] id: FYPO:0002640 name: sensitive to clotrimazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to clotrimazole. Cells stop growing (and may die) at a concentration of clotrimazole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to clotrimazole" EXACT [PomBase:mah] synonym: "sensitive to clotrimazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to clotrimazole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-12T11:46:38Z [Term] id: FYPO:0002641 name: sensitive to micafungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to micafungin. Cells stop growing (and may die) at a concentration of micafungin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to micafungin" EXACT [PomBase:mah] synonym: "sensitive to micafungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to micafungin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-12T11:47:24Z [Term] id: FYPO:0002642 name: sensitive to amphotericin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amphotericin B. Cells stop growing (and may die) at a concentration of amphotericin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to amphotericin B" EXACT [PomBase:mah] synonym: "sensitive to amphotericin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to amphotericin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-12T11:48:40Z [Term] id: FYPO:0002643 name: normal growth on clotrimazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing clotrimazole." [PomBase:mah] synonym: "normal cell population growth in presence of clotrimazole" EXACT [PomBase:mah] synonym: "normal cell population growth on clotrimazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to clotrimazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on clotrimazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-12T11:50:34Z [Term] id: FYPO:0002644 name: obsolete decreased protein serine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-serine phosphorylation during vegetative growth" EXACT [GO:0018105, PomBase:mah] synonym: "decreased protein serine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased serine phosphorylation during vegetative growth" EXACT [PomBase:al] synonym: "reduced protein serine phosphorylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001838 created_by: midori creation_date: 2013-09-12T12:43:00Z [Term] id: FYPO:0002645 name: obsolete decreased protein threonine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-threonine phosphorylation during vegetative growth" EXACT [GO:0018107, PomBase:mah] synonym: "decreased protein threonine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased threonine phosphorylation during vegetative growth" EXACT [PomBase:al] synonym: "reduced protein threonine phosphorylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001838 created_by: midori creation_date: 2013-09-12T12:47:56Z [Term] id: FYPO:0002646 name: obsolete decreased protein serine phosphorylation during mitosis def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitosis." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-serine phosphorylation during mitosis" EXACT [GO:0018105, PomBase:mah] synonym: "decreased protein serine phosphorylation during M phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein serine phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein serine phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased serine phosphorylation during mitosis" EXACT [PomBase:al] synonym: "reduced protein serine phosphorylation during mitosis" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004357 created_by: midori creation_date: 2013-09-12T12:52:24Z [Term] id: FYPO:0002647 name: obsolete decreased protein threonine phosphorylation during mitosis def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitosis." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-threonine phosphorylation during mitosis" EXACT [GO:0018107, PomBase:mah] synonym: "decreased protein threonine phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein threonine phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein threonine phosphorylation during mitotic M phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased threonine phosphorylation during mitosis" EXACT [PomBase:al] synonym: "reduced protein threonine phosphorylation during mitosis" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004357 created_by: midori creation_date: 2013-09-12T13:03:07Z [Term] id: FYPO:0002648 name: increased protein phosphorylation during mitotic prometaphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during prometaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during mitotic prometaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during prometaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-09-12T13:04:18Z [Term] id: FYPO:0002649 name: elongated kinetochore during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the kinetochore is longer than normal during mitosis." [PomBase:mah] comment: This phenotype can be observed in metaphase and/or anaphase. Use this term in cases where "stretching" describes the apparent length of a single kinetochore. For example, a merotelically attached kinetochore can stretch to the extent that it appears as two spots by fluorescence microscopy. synonym: "elongated kinetochore during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "elongated kinetochore during mitotic M phase" RELATED [PomBase:mah] synonym: "elongated kinetochores during mitosis" EXACT [PomBase:vw] synonym: "extended kinetochore during mitosis" EXACT [PomBase:vw] synonym: "stretched kinetochore during mitosis" RELATED [PomBase:vw] is_a: FYPO:0000050 ! abnormal kinetochore morphology during vegetative growth created_by: midori creation_date: 2013-09-12T13:42:23Z [Term] id: FYPO:0002650 name: split kinetochore during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the kinetochore is divided into two or more parts." [PomBase:mah] synonym: "split kinetochore during mitotic cell cycle" RELATED [PomBase:mah] synonym: "split kinetochores during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000050 ! abnormal kinetochore morphology during vegetative growth is_a: FYPO:0005647 ! split kinetochore created_by: midori creation_date: 2013-09-12T13:45:31Z [Term] id: FYPO:0002651 name: merotelic kinetochore attachment def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division results in the connection of a single kinetochore to both spindle poles." [PMID:17426725, PMID:21306900] comment: Also consider 'lagging chromosomes' (FYPO:0002090), because merotelic attachment often causes chromosomes to lag during segregation. synonym: "merotelic attachment of spindle microtubules to kinetochore" EXACT [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore created_by: midori creation_date: 2013-09-12T14:10:20Z [Term] id: FYPO:0002652 name: excess intracellular endomembrane system present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more intracellular endomembrane system structures than normal. The endomembrane system includes the endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope; in this phenotype, excess plasma membrane does not accumulate, but increased amounts of one or more internal intracellular endomembrane system structures may be present." [PMID:21899677, PomBase:mah, PomBase:vw] synonym: "accumulation of internal endomembrane system structures" EXACT [PomBase:vw] synonym: "excess intracellular endomembrane system present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "excess intracellular endomembrane system present during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of intracellular endomembrane system structures" RELATED [PomBase:mah] synonym: "intracellular endomembrane system structures present in greater numbers" EXACT [PomBase:mah] is_a: FYPO:0002404 ! abnormal endomembrane system created_by: midori creation_date: 2013-09-12T15:12:13Z [Term] id: FYPO:0002653 name: decreased vacuolar import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of vacuolar import, i.e. the transport of substances into the vacuole, is decreased." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) into the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "decreased vacuolar import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar protein import" NARROW [PomBase:mah] synonym: "reduced vacuolar import" EXACT [PomBase:mah] is_a: FYPO:0000598 ! decreased vacuolar transport created_by: midori creation_date: 2013-09-12T15:27:05Z [Term] id: FYPO:0002654 name: enlarged exocytic vesicles def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which exocytic vesicles are larger than normal." [PomBase:mah] synonym: "enlarged exocytic vesicles during mitotic cell cycle" RELATED [PomBase:mah] synonym: "enlarged exocytic vesicles during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2013-09-12T15:31:06Z [Term] id: FYPO:0002655 name: enlarged exocytic vesicles present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles than normal, and the vesicles are larger than normal." [PomBase:mah] synonym: "accumulation of enlarged exocytic vesicles" RELATED [PomBase:vw] synonym: "additional enlarged exocytic vesicles present" EXACT [PomBase:mah] synonym: "enlarged exocytic vesicles present in greater numbers" EXACT [PomBase:mah] synonym: "enlarged exocytic vesicles present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "enlarged exocytic vesicles present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "enlarged exocytotic vesicles present in increased numbers" EXACT [GO:0070382] synonym: "enlarged post-Golgi secretory vesicles present in increased numbers" RELATED [PomBase:vw] synonym: "extra enlarged exocytic vesicles" EXACT [PomBase:mah] is_a: FYPO:0002086 ! exocytic vesicles present in increased numbers is_a: FYPO:0002654 ! enlarged exocytic vesicles relationship: has_part FYPO:0002086 ! exocytic vesicles present in increased numbers relationship: has_part FYPO:0002654 ! enlarged exocytic vesicles created_by: midori creation_date: 2013-09-12T15:32:02Z [Term] id: FYPO:0002656 name: decreased actin filament binding def: "A molecular function phenotype in which the binding of a protein to one or more actin filaments occurs to a lower extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased F-actin binding" EXACT [PomBase:mah] synonym: "decreased filamentous actin binding" RELATED [PomBase:mah] synonym: "decreased protein-protein interaction with actin filament" EXACT [PomBase:mah] synonym: "reduced actin filament binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2013-09-12T16:18:53Z [Term] id: FYPO:0002657 name: normal occurrence of NETO def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) occurs to the same extent as in wild-type cells." [PomBase:mah] synonym: "normal frequency of NETO" EXACT [PomBase:mah] synonym: "normal NETO frequency" EXACT [PomBase:mah] synonym: "normal NETO occurrence" EXACT [PomBase:mah] synonym: "normal occurrence of activation of bipolar cell growth" RELATED [PomBase:mah] synonym: "normal occurrence of cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "normal occurrence of NETO during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal occurrence of NETO during vegetative growth" EXACT [PomBase:mah] synonym: "normal occurrence of new end take-off" EXACT [PomBase:mah] synonym: "normal occurrence of switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2013-09-12T16:37:35Z [Term] id: FYPO:0002658 name: increased cellular trehalose 6-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular trehalose 6-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular trehalose 6-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular trehalose-6P level" EXACT [PomBase:al] synonym: "increased trehalose 6-phosphate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-09-18T11:47:38Z [Term] id: FYPO:0002659 name: increased cellular trehalose 6-phosphate level during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is higher than normal when the cell is subject to heat shock." [PomBase:mah] synonym: "increased cellular trehalose 6-phosphate level during heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular trehalose 6-phosphate level during vegetative growth and during heat shock" EXACT [PomBase:mah] synonym: "increased cellular trehalose-6P level during heat shock" EXACT [PomBase:al] synonym: "increased trehalose 6-phosphate accumulation during heat shock" RELATED [PomBase:mah] is_a: FYPO:0002658 ! increased cellular trehalose 6-phosphate level created_by: midori creation_date: 2013-09-18T11:47:57Z [Term] id: FYPO:0002660 name: decreased cellular trehalose 6-phosphate level def: "A cell phenotype in which the amount of trehalose 6-phosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular trehalose 6-phosphate accumulation" RELATED [PomBase:mah] synonym: "decreased cellular trehalose-6P level" EXACT [PomBase:al] synonym: "reduced cellular trehalose 6-phosphate level" EXACT [PomBase:mah] is_a: FYPO:0001447 ! decreased cellular trehalose level created_by: midori creation_date: 2013-09-18T11:48:34Z [Term] id: FYPO:0002661 name: decreased cellular trehalose 6-phosphate level during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is lower than normal when the cell is subject to heat shock." [PomBase:mah] synonym: "decreased cellular trehalose 6-phosphate level during heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular trehalose 6-phosphate level during vegetative growth and during heat shock" EXACT [PomBase:mah] synonym: "decreased cellular trehalose-6P level during heat shock" EXACT [PomBase:al] synonym: "decreased trehalose 6-phosphate accumulation during heat shock" RELATED [PomBase:mah] synonym: "reduced cellular trehalose 6-phosphate level during heat shock" EXACT [PomBase:mah] is_a: FYPO:0002660 ! decreased cellular trehalose 6-phosphate level created_by: midori creation_date: 2013-09-18T11:50:45Z [Term] id: FYPO:0002662 name: decreased cellular trehalose level during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to heat shock." [PomBase:mah] synonym: "decreased cellular trehalose level during heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular trehalose level during vegetative growth and during heat shock" EXACT [PomBase:mah] synonym: "decreased trehalose accumulation during heat shock" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level during heat shock" EXACT [PomBase:mah] is_a: FYPO:0001447 ! decreased cellular trehalose level created_by: midori creation_date: 2013-09-18T11:57:16Z [Term] id: FYPO:0002663 name: alpha,alpha-trehalase activity increase abolished during cellular response to hydrogen peroxide def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a hydrogen peroxide stimulus." [PomBase:mah] synonym: "absent increase in trehalase activity following hydrogen peroxide stimulus" EXACT [PomBase:al] synonym: "alpha,alpha-trehalase activity increase abolished during cellular response to H2O2" EXACT [PomBase:mah] synonym: "neutral trehalase activity increase abolished during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "trehalase activity increase abolished during cellular response to hydrogen peroxide" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity is_a: FYPO:0001484 ! abnormal cellular response to nutrient created_by: midori creation_date: 2013-09-18T12:19:11Z [Term] id: FYPO:0002664 name: increased level of stress responsive gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of cellular response to stress responsive gene mRNA" EXACT [PomBase:al] synonym: "increased level of stress response gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of stress responsive gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of stress responsive gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of stress responsive gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased mRNA level of stress responsive genes during vegetative growth" EXACT [PomBase:al] synonym: "increased stress responsive gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0004363 ! altered level of stress responsive gene mRNA during vegetative growth created_by: midori creation_date: 2013-09-18T16:06:04Z [Term] id: FYPO:0002665 name: abnormal peptide-serine-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide-serine-N-acetyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-09-18T16:08:31Z [Term] id: FYPO:0002666 name: abolished peptide-serine-N-acetyltransferase activity def: "A molecular function phenotype in which peptide-serine-N-acetyltransferase activity is absent." [PomBase:mah] synonym: "peptide-serine-N-acetyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002665 ! abnormal peptide-serine-N-acetyltransferase activity created_by: midori creation_date: 2013-09-18T16:08:47Z [Term] id: FYPO:0002667 name: decreased peptide-serine-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide-serine-N-acetyltransferase activity is decreased." [PomBase:mah] synonym: "reduced peptide-serine-N-acetyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002665 ! abnormal peptide-serine-N-acetyltransferase activity created_by: midori creation_date: 2013-09-18T16:09:01Z [Term] id: FYPO:0002668 name: normal peptide-serine-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide-serine-N-acetyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2013-09-18T16:12:26Z [Term] id: FYPO:0002669 name: abnormal peptide-glutamate-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide-glutamate-N-acetyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-09-18T16:13:17Z [Term] id: FYPO:0002670 name: increased peptide-glutamate-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide-glutamate-N-acetyltransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002669 ! abnormal peptide-glutamate-N-acetyltransferase activity created_by: midori creation_date: 2013-09-18T16:13:24Z [Term] id: FYPO:0002671 name: increased concentration of protein in growth medium def: "A phenotype in which the concentration of one or more proteins released into the growth medium by cells is higher than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased concentration of proteins in growth medium" EXACT [PomBase:al] synonym: "increased level of protein in growth medium" EXACT [PomBase:mah] synonym: "increased release of protein into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2013-09-18T16:26:49Z [Term] id: FYPO:0002672 name: normal growth on rapamycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing rapamycin." [PomBase:mah] synonym: "normal cell population growth in presence of rapamycin" EXACT [PomBase:mah] synonym: "normal cell population growth on rapamycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to rapamycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on rapamycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-18T16:35:24Z [Term] id: FYPO:0002673 name: normal growth on torin1 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing torin1." [PomBase:mah] synonym: "normal cell population growth in presence of torin1" EXACT [PomBase:mah] synonym: "normal cell population growth on torin1" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to torin1" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on torin 1" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on torin1" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-18T16:36:46Z [Term] id: FYPO:0002674 name: normal protein localization to plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to plasma membrane" EXACT [PomBase:mah] synonym: "normal protein localization to plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to plasma membrane during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-09-18T16:43:41Z [Term] id: FYPO:0002675 name: increased cellular dTDP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTDP measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dTDP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular dTDP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased dTDP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-09-18T16:45:22Z [Term] id: FYPO:0002676 name: dTTP absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTTP measured in a cell is too low to detect." [PomBase:mah] synonym: "dTTP absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "dTTP absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0002572 ! decreased cellular dTTP level created_by: midori creation_date: 2013-09-18T16:46:00Z [Term] id: FYPO:0002677 name: abnormal protein phosphorylation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2013-09-19T11:41:10Z [Term] id: FYPO:0002678 name: abolished protein phosphorylation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein phosphorylation abolished" EXACT [PomBase:mah] is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2013-09-19T11:42:17Z [Term] id: FYPO:0002679 name: decreased protein phosphorylation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "reduced protein phosphorylation" EXACT [PomBase:mah] is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2013-09-19T11:56:10Z [Term] id: FYPO:0002680 name: increased protein phosphorylation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2013-09-19T12:00:31Z [Term] id: FYPO:0002681 name: increased protein phosphorylation during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during nitrogen depletion" EXACT [PomBase:vw] synonym: "increased protein phosphorylation during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002680 ! increased protein phosphorylation is_a: FYPO:0005033 ! abnormal protein phosphorylation during nitrogen starvation created_by: midori creation_date: 2013-09-19T12:04:02Z [Term] id: FYPO:0002682 name: increased resistance to chemical def: "A phenotype in which cells in a population show increased resistance to a chemical stimulus. Resistance to a chemical is usually measured by determining the maximum concentration of the chemical at which a population of cells grow and divide, and cells are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type cells to grow." [PomBase:mah] synonym: "resistance to chemicals: increased" RELATED [SGD:phenotype_annotation] synonym: "resistant to chemical" EXACT [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth created_by: midori creation_date: 2013-09-19T12:14:30Z [Term] id: FYPO:0002683 name: increased sensitivity to chemical def: "A phenotype in which cells in a population show decreased resistance to a chemical stimulus. Resistance to a chemical is measured by determining the maximum concentration of the chemical at which a population of cells grow and divide. Typically, cells are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type cells to grow." [PomBase:mah] synonym: "resistance to chemicals: decreased" RELATED [SGD:phenotype_annotation] synonym: "sensitive to chemical" EXACT [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth created_by: midori creation_date: 2013-09-19T12:14:37Z [Term] id: FYPO:0002684 name: sensitive to phlorizin during spore germination def: "A phenotype in which germinating spores show increased sensitivity to phlorizin. Cells stop growing (and may die) at a concentration of phlorizin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to phlorizin" EXACT [PomBase:mah] synonym: "sensitive to phloridzin during spore germination" EXACT [CHEBI:8113, PomBase:mah] is_a: FYPO:0002683 ! increased sensitivity to chemical created_by: midori creation_date: 2013-09-19T12:58:01Z [Term] id: FYPO:0002685 name: increased cellular trehalose level def: "A cell phenotype in which the amount of trehalose measured in a cell is higher than normal." [PomBase:mah] synonym: "increased trehalose accumulation" RELATED [PomBase:mah] is_a: FYPO:0001446 ! altered cellular trehalose level created_by: midori creation_date: 2013-09-19T13:33:21Z [Term] id: FYPO:0002686 name: increased cellular trehalose level in spore def: "A cell phenotype in which the amount of trehalose measured in a spore is higher than normal." [PomBase:mah] synonym: "increased trehalose accumulation in spore" RELATED [PomBase:mah] is_a: FYPO:0002685 ! increased cellular trehalose level created_by: midori creation_date: 2013-09-19T13:34:04Z [Term] id: FYPO:0002687 name: normal telomere length during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomere length is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal telomere length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth is_a: FYPO:0006515 ! normal telomere length created_by: midori creation_date: 2013-09-19T14:08:05Z [Term] id: FYPO:0002688 name: mitotic spindle collapse without elongation during prophase def: "A cell phenotype in which a short mitotic spindle assembles, but does not elongate. The spindle pole bodies fail to separate, and often become spatially closer together, suggesting that the spindle shrinks." [PMID:23885124, PomBase:mah] synonym: "broken mitotic spindle without elongation during prophase" RELATED [PomBase:vw] synonym: "mitotic spindle breakage without elongation during prophase" RELATED [PomBase:vw] synonym: "mitotic spindle collapse without elongation during prophase during vegetative growth" EXACT [PomBase:mah] synonym: "SPB convergence" EXACT [PMID:23885124] synonym: "spindle collapse without elongation during mitotic prophase" EXACT [PomBase:mah] synonym: "spindle collapse without elongation during prophase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle pole body convergence" EXACT [PMID:23885124] is_a: FYPO:0006173 ! abolished mitotic spindle elongation during prophase is_a: FYPO:0006475 ! mitotic spindle collapse relationship: has_part FYPO:0006173 ! abolished mitotic spindle elongation during prophase created_by: midori creation_date: 2013-09-19T14:15:09Z [Term] id: FYPO:0002689 name: sensitive to cumene hydroperoxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cumene hydroperoxide. Cells stop growing (and may die) at a concentration of cumene hydroperoxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cumene hydroperoxide" EXACT [PomBase:mah] synonym: "sensitive to cumene hydroperoxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cumene hydroperoxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-19T14:48:08Z [Term] id: FYPO:0002690 name: normal growth on cumene hydroperoxide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cumene hydroperoxide." [PomBase:mah] synonym: "normal cell population growth in presence of cumene hydroperoxide" EXACT [PomBase:mah] synonym: "normal cell population growth on cumene hydroperoxide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cumene hydroperoxide" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cumene hydroperoxide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-19T15:00:38Z [Term] id: FYPO:0002691 name: normal growth on menadione def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing menadione." [PomBase:mah] synonym: "normal cell population growth in presence of menadione" EXACT [PomBase:mah] synonym: "normal cell population growth on menadione" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to menadione" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on menadione" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-19T15:04:33Z [Term] id: FYPO:0002692 name: sensitive to paraquat def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to paraquat. Cells stop growing (and may die) at a concentration of paraquat that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to paraquat" EXACT [PomBase:mah] synonym: "sensitive to paraquat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to paraquat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-19T15:15:08Z [Term] id: FYPO:0002693 name: resistance to diamide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) than normal." [PomBase:mah] synonym: "resistance to diamide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to diamide during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958] synonym: "resistant to diamide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-09-19T15:17:54Z [Term] id: FYPO:0002694 name: resistance to hygromycin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hygromycin B than normal." [PomBase:mah] synonym: "resistance to hygromycin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to hygromycin B during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to hygromycin B" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-09-19T15:19:33Z [Term] id: FYPO:0002695 name: abnormal methylenetetrahydrofolate reductase (NADPH) activity def: "A molecular function phenotype in which the observed rate of methylenetetrahydrofolate reductase (NADPH) activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-09-19T15:31:14Z [Term] id: FYPO:0002696 name: abolished methylenetetrahydrofolate reductase (NADPH) activity def: "A molecular function phenotype in which methylenetetrahydrofolate reductase (NADPH) activity is absent." [PomBase:mah] synonym: "methylenetetrahydrofolate reductase (NADPH) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002695 ! abnormal methylenetetrahydrofolate reductase (NADPH) activity created_by: midori creation_date: 2013-09-19T15:31:23Z [Term] id: FYPO:0002697 name: decreased methylenetetrahydrofolate reductase (NADPH) activity def: "A molecular function phenotype in which the observed rate of methylenetetrahydrofolate reductase (NADPH) activity is decreased." [PomBase:mah] synonym: "reduced methylenetetrahydrofolate reductase (NADPH) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002695 ! abnormal methylenetetrahydrofolate reductase (NADPH) activity created_by: midori creation_date: 2013-09-19T15:31:43Z [Term] id: FYPO:0002698 name: increased methylenetetrahydrofolate reductase (NADPH) activity def: "A molecular function phenotype in which the observed rate of methylenetetrahydrofolate reductase (NADPH) activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002695 ! abnormal methylenetetrahydrofolate reductase (NADPH) activity created_by: midori creation_date: 2013-09-19T15:32:15Z [Term] id: FYPO:0002699 name: decreased protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "decreased protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "decreased protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "decreased protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "reduced protein localization to actomyosin contractile ring" EXACT [PomBase:mah] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2013-09-19T15:36:39Z [Term] id: FYPO:0002700 name: increased protein kinase activity def: "A molecular function phenotype in which the observed rate of a protein kinase activity is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2013-09-19T16:06:33Z [Term] id: FYPO:0002701 name: sensitive to torin1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to torin1. Cells stop growing (and may die) at a concentration of torin1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to torin1" EXACT [PomBase:mah] synonym: "sensitive to torin 1" EXACT [PomBase:mah] synonym: "sensitive to torin1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to torin1 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-19T16:16:01Z [Term] id: FYPO:0002702 name: circularized chromosome def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or more chromosomes forms a circle by fusion of its ends." [PMID:11349150, PomBase:mah] synonym: "circular chromosomes" EXACT [PomBase:mah] synonym: "circularised chromosome" EXACT [PomBase:mah] synonym: "circularized chromosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "circularized chromosome during vegetative growth" EXACT [PomBase:mah] synonym: "fused telomeres" RELATED [PomBase:mah] synonym: "NHEJ-dependent telomere fusions" NARROW [] synonym: "telomere end fusion" RELATED [PomBase:mah] synonym: "telomere end-to-end fusion" EXACT [] synonym: "telomeres fused" RELATED [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2013-09-25T12:14:38Z [Term] id: FYPO:0002703 name: increased protein level in autophagosome def: "A cell phenotype in which the amount of protein measured in autophagosomes is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased autophagosomal protein level during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level in autophagic vacuole during vegetative growth" EXACT [GO:0005776] synonym: "increased protein level in autophagosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level in autophagosome during vegetative growth" EXACT [PomBase:mah] synonym: "protein accumulation in autophagosomes" EXACT [PomBase:vw] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2013-09-25T12:39:09Z [Term] id: FYPO:0002704 name: normal autophagic vacuole docking def: "A cellular process phenotype in which autophagic vacuole docking is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process relationship: part_of FYPO:0000385 ! normal macroautophagy created_by: midori creation_date: 2013-09-25T12:41:21Z [Term] id: FYPO:0002705 name: sensitive to methionine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methionine. Cells stop growing (and may die) at a concentration of methionine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to methionine" EXACT [PomBase:mah] synonym: "methionine inhibited" EXACT [PomBase:vw] synonym: "sensitive to methionine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to methionine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-09-25T12:50:43Z [Term] id: FYPO:0002706 name: resistance to cordycepin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cordycepin than normal." [PomBase:mah] synonym: "resistance to cordycepin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cordycepin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to cordycepin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-09-25T13:04:40Z [Term] id: FYPO:0002707 name: normal growth on cordycepin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cordycepin." [PomBase:mah] synonym: "normal cell population growth in presence of cordycepin" EXACT [PomBase:mah] synonym: "normal cell population growth on cordycepin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cordycepin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cordycepin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-09-25T13:07:13Z [Term] id: FYPO:0002708 name: abolished prospore formation def: "A cellular process phenotype in which prospore formation does not occur. In prospore formation, each haploid nucleus becomes encapsulated by a double membrane." [PomBase:mah] comment: This term can be used to describe mutants in which meiotic nuclear division takes place, forming four haploid nuclei, but ascospores do not form around the nuclei. synonym: "abolished ascospore-type prospore assembly" EXACT [GO:0032121] synonym: "abolished forespore formation" EXACT [PomBase:mah] synonym: "forespore formation abolished" EXACT [PomBase:mah] is_a: FYPO:0000196 ! abnormal prospore formation created_by: midori creation_date: 2013-09-25T14:36:01Z [Term] id: FYPO:0002709 name: spindle pole body absent from cell def: "A cell phenotype in which the cell does not contain a detectable spindle pole body." [PomBase:mah] synonym: "absent spindle pole body" EXACT [PomBase:mah] synonym: "SPB absent from cell" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2013-09-25T14:46:19Z [Term] id: FYPO:0002710 name: spindle pole body absent from cell after meiosis II def: "A cell phenotype in which nuclei formed by the second meiotic nuclear division do not contain detectable spindle pole bodies." [PomBase:mah] synonym: "absent spindle pole body after meiosis II" EXACT [PomBase:mah] synonym: "absent spindle pole body after second meiotic nuclear division" EXACT [PomBase:vw] synonym: "SPB absent from cell after meiosis II" EXACT [PomBase:mah] is_a: FYPO:0002709 ! spindle pole body absent from cell created_by: midori creation_date: 2013-09-25T14:48:18Z [Term] id: FYPO:0002711 name: abnormal nuclear separation after meiosis def: "A cellular process phenotype in which the haploid nuclei formed by meiotic nuclear division do not separate normally. Nuclei may be closer together than normal, or remain attached by an incompletely separated outer nuclear membrane, or both." [PMID:1417417, PomBase:mah] synonym: "abnormal nuclear distribution after meiosis" EXACT [PomBase:mah] synonym: "abnormal nuclear separation after meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal nuclear separation during sporulation" RELATED [PomBase:mah] synonym: "abnormal nuclear separation in ascus" EXACT [PomBase:mah] synonym: "abnormal separation of nuclei in ascus" EXACT [PomBase:vw] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2013-09-25T14:53:56Z [Term] id: FYPO:0002712 name: decreased DNA recombination def: "A cellular process phenotype in which the occurrence of DNA recombination is decreased." [PomBase:mah] synonym: "decreased DNA recombination frequency" EXACT [PomBase:mah] synonym: "decreased DNA recombination rate" RELATED [PomBase:mah] synonym: "decreased recombination" EXACT [PomBase:vw] synonym: "reduced DNA recombination" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2013-09-25T15:43:00Z [Term] id: FYPO:0002713 name: decreased DNA recombination at mating type locus def: "A cellular process phenotype in which the occurrence of DNA recombination is decreased at the mating type locus." [PomBase:mah] synonym: "decreased DNA recombination frequency at mating type locus" EXACT [PomBase:mah] synonym: "decreased DNA recombination rate at mating type locus" RELATED [PomBase:mah] synonym: "decreased recombination at mating type locus" EXACT [PomBase:vw] synonym: "reduced DNA recombination at mating type locus" EXACT [PomBase:mah] is_a: FYPO:0002712 ! decreased DNA recombination created_by: midori creation_date: 2013-09-25T15:46:03Z [Term] id: FYPO:0002714 name: protein mislocalized to Golgi apparatus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the Golgi apparatus is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the Golgi in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to Golgi apparatus" EXACT [PomBase:vw] synonym: "protein mislocalised to Golgi apparatus" EXACT [PomBase:mah] synonym: "protein mislocalised to Golgi apparatus during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to Golgi apparatus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to Golgi apparatus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2013-09-25T15:52:17Z [Term] id: FYPO:0002715 name: normal Golgi apparatus morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure the Golgi apparatus is normal." [PomBase:mah] comment: Note that an abnormal Golgi organization process may, but does not necessarily, result in abnormal Golgi morphology. synonym: "normal Golgi apparatus morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal Golgi apparatus morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal Golgi morphology" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2013-09-25T15:53:38Z [Term] id: FYPO:0002716 name: normal vacuole fusion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is normal (i.e. indistinguishable from wild type)." [GO:0042144, PomBase:mah] synonym: "normal homotypic vacuole fusion during vegetative growth" EXACT [GO:0042144] synonym: "normal vacuole fusion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuole fusion, non-autophagic, during vegetative growth" EXACT [GO:0042144] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2013-09-26T11:47:38Z [Term] id: FYPO:0002717 name: normal vacuole fusion during cellular hypotonic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion is normal (i.e. indistinguishable from wild type) during a cellular response to a hypotonic environment." [PomBase:mah] synonym: "normal homotypic vacuole fusion during cellular hypotonic response" EXACT [GO:0042144] synonym: "normal vacuole fusion during cellular hypotonic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuole fusion during cellular hypotonic response during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuole fusion during hypotonic stress" EXACT [PomBase:al] synonym: "normal vacuole fusion, non-autophagic, during cellular hypotonic response" EXACT [GO:0042144] is_a: FYPO:0002716 ! normal vacuole fusion during vegetative growth created_by: midori creation_date: 2013-09-26T11:49:34Z [Term] id: FYPO:0002718 name: abnormal protein localization to septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the septum and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to septum" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell septum" EXACT [PomBase:al] synonym: "abnormal protein localization to division septum" EXACT [GO:0000935, PomBase:mah] synonym: "abnormal protein localization to septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2013-09-26T12:13:16Z [Term] id: FYPO:0002719 name: decreased protein localization to septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to septum" EXACT [PomBase:mah] synonym: "decreased protein localization to cell septum" EXACT [PomBase:al] synonym: "decreased protein localization to division septum" EXACT [GO:0000935, PomBase:mah] synonym: "decreased protein localization to septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to septum during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to septum" EXACT [PomBase:mah] is_a: FYPO:0002718 ! abnormal protein localization to septum created_by: midori creation_date: 2013-09-26T12:13:26Z [Term] id: FYPO:0002720 name: sensitive to beta-glucanase def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more enzymes that degrades cell wall polysaccharides by hydrolyzing beta-glucan linkages. Cells stop growing (and may die) at a concentration of such enzymes that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to beta-glucanase" EXACT [PomBase:mah] synonym: "sensitive to beta-glucanase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to beta-glucanase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001190 ! sensitive to cell wall-degrading enzymes created_by: midori creation_date: 2013-09-26T13:22:37Z [Term] id: FYPO:0002721 name: resistance to alpha-glucanase def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration than normal of one or more enzymes that degrades cell wall polysaccharides by hydrolyzing alpha-glucan linkages." [PomBase:mah] synonym: "resistance to alpha-glucanase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to alpha-glucanase during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to alpha-glucanase" EXACT [PomBase:mah] is_a: FYPO:0001882 ! resistance to cell wall-degrading enzymes created_by: midori creation_date: 2013-09-26T13:59:44Z [Term] id: FYPO:0002722 name: phytochelatin absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in a cell is too low to detect." [PomBase:mah] synonym: "cadystin absent from cell" EXACT [PMID:2894829] synonym: "phytochelatin absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "phytochelatin absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0002829 ! decreased cellular phytochelatin level created_by: midori creation_date: 2013-09-26T14:05:14Z [Term] id: FYPO:0002723 name: increased cellular pigment accumulation during cellular response to cadmium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased during a cellular response to cadmium ion." [PomBase:mah] comment: Note that normal cells do not accumulate detectable levels of any pigment; for this reason, FYPO does not include separate terms for 'increased' and 'abnormal' pigment accumulation. Also note that pigment accumulates in the vacuole. This term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "abnormal cellular pigment accumulation during cellular response to cadmium ion" EXACT [PomBase:mah] synonym: "altered colony color during cellular response to cadmium ion" RELATED [PomBase:al, PomBase:mah] synonym: "altered colony colour during cellular response to cadmium ion" RELATED [PomBase:al, PomBase:mah] synonym: "increased cellular pigment accumulation during cellular response to cadmium" EXACT [PomBase:mah] synonym: "increased cellular pigment accumulation during cellular response to cadmium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular pigment accumulation during cellular response to cadmium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000741 ! increased cellular pigment accumulation created_by: midori creation_date: 2013-09-26T14:51:13Z [Term] id: FYPO:0002724 name: inviable after spore germination, single or double cell division, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and undergoes one or two rounds of cell division." [PomBase:mah] synonym: "inviable following spore germination, single or double cell division, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0002421 ! inviable after spore germination, single or double cell division, abnormal cell shape relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2013-09-26T14:54:57Z [Term] id: FYPO:0002725 name: decreased L-aminoadipate-semialdehyde dehydrogenase activity def: "A molecular function phenotype in which the observed rate of L-aminoadipate-semialdehyde dehydrogenase activity is decreased." [PomBase:mah] synonym: "decreased alpha-aminoadipate reductase activity" EXACT [GO:0004043] synonym: "reduced alpha-aminoadipate reductase activity" EXACT [GO:0004043] synonym: "reduced L-aminoadipate-semialdehyde dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0001674 ! abnormal L-aminoadipate-semialdehyde dehydrogenase activity created_by: midori creation_date: 2013-09-26T15:01:57Z [Term] id: FYPO:0002726 name: abnormal saccharopine dehydrogenase activity def: "A molecular function phenotype in which the observed rate of saccharopine dehydrogenase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-09-26T15:03:42Z [Term] id: FYPO:0002727 name: decreased saccharopine dehydrogenase activity def: "A molecular function phenotype in which the observed rate of saccharopine dehydrogenase activity is decreased." [PomBase:mah] synonym: "reduced saccharopine dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0002726 ! abnormal saccharopine dehydrogenase activity created_by: midori creation_date: 2013-09-26T15:03:52Z [Term] id: FYPO:0002728 name: inviable swollen elongated cell with enlarged nucleus upon entry into stationary phase def: "A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and in which the nucleus is larger than normal, when the cell is in a culture entering stationary phase. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PMID:2743431, PomBase:mah] comment: This phenotype is usually seen in diploid cells, so consider also annotating to 'increased spontaneous diploidization' (FYPO:0000252). synonym: "lethal; swollen elongated cell with enlarged nucleus upon entry into stationary phase" EXACT [PomBase:mah] is_a: FYPO:0002083 ! inviable swollen elongated cell with enlarged nucleus created_by: midori creation_date: 2013-09-26T16:56:31Z [Term] id: FYPO:0002729 name: DNA content increased def: "A cell phenotype in which the total amount of DNA in a cell is greater than normal." [PomBase:mah] synonym: "increased DNA content" EXACT [PomBase:mah] synonym: "increased DNA level" EXACT [PomBase:mah] is_a: FYPO:0000990 ! increased level of substance in cell is_a: FYPO:0004320 ! altered DNA level created_by: midori creation_date: 2013-10-01T14:10:44Z [Term] id: FYPO:0002730 name: DNA content increased during stationary phase def: "A cell phenotype in which the total amount of DNA in a cell is greater than normal when the cell is in a culture in stationary phase." [PomBase:mah] synonym: "increased DNA content during stationary phase" EXACT [PomBase:mah] synonym: "increased DNA level during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0002729 ! DNA content increased created_by: midori creation_date: 2013-10-01T14:15:45Z [Term] id: FYPO:0002731 name: mononucleate def: "A physical cellular phenotype in which a cell contains a single nucleus." [PomBase:mah] synonym: "mononucleate cell" EXACT [PomBase:mah] is_a: FYPO:0000136 ! cellular physical quality phenotype created_by: midori creation_date: 2013-10-01T14:26:14Z [Term] id: FYPO:0002732 name: mononucleate cell with increased DNA content during stationary phase def: "A physical cellular phenotype in which a cell contains a single nucleus, and more DNA than normal, when the cell is in a culture in stationary phase." [PomBase:mah] is_a: FYPO:0002729 ! DNA content increased is_a: FYPO:0002731 ! mononucleate created_by: midori creation_date: 2013-10-01T14:28:35Z [Term] id: FYPO:0002733 name: inviable after spore germination, multiple cell divisions, elongated tapered cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and tapered, i.e. tapers at one end to a diameter smaller than the other, undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated bottle-shaped cell" EXACT [PomBase:vw] synonym: "inviable after spore germination, multiple cell divisions, elongated bottle/skittle cell" EXACT [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated skittle-shaped cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, elongated tapered cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, elongated tapered cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, elongated tapered cell" EXACT [PomBase:mah] is_a: FYPO:0002262 ! inviable after spore germination, multiple cell divisions, elongated cell created_by: midori creation_date: 2013-10-01T14:37:15Z [Term] id: FYPO:0002734 name: abnormal cell cycle process def: "A cellular process phenotype in which a cell does not execute a cell cycle process normally. A cell cycle process is any of the processes that form part of the cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation." [GO:0022402, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000011 ! abnormal cell cycle created_by: midori creation_date: 2013-10-01T15:08:57Z [Term] id: FYPO:0002735 name: abnormal cell cycle phase def: "A cellular process phenotype in which a cell does not proceed normally through a specific cell cycle phase. A cell cycle phase is any of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GO:0022403, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000011 ! abnormal cell cycle created_by: midori creation_date: 2013-10-01T15:09:18Z [Term] id: FYPO:0002736 name: abnormal mitotic cell cycle phase def: "A cellular process phenotype in which a cell does not proceed normally through a specific mitotic cell cycle phase. A mitotic cell cycle phase is any of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GO:0022403, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000059 ! abnormal mitotic cell cycle is_a: FYPO:0002735 ! abnormal cell cycle phase created_by: midori creation_date: 2013-10-01T15:14:48Z [Term] id: FYPO:0002737 name: abnormal mitotic cell cycle process def: "A cellular process phenotype in which a cell does not execute a mitotic cell cycle process normally. A mitotic cell cycle process is any of the processes that form part of the mitotic cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation during the vegetative growth phase of the life cycle." [GO:0022402, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal mitotic cell cycle process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000059 ! abnormal mitotic cell cycle is_a: FYPO:0002734 ! abnormal cell cycle process created_by: midori creation_date: 2013-10-01T15:15:09Z [Term] id: FYPO:0002738 name: abnormal meiotic cell cycle phase def: "A cellular process phenotype in which a cell does not proceed normally through a specific meiotic cell cycle phase. A meiotic cell cycle phase is any of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GO:0022403, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000052 ! abnormal meiotic cell cycle is_a: FYPO:0002735 ! abnormal cell cycle phase created_by: midori creation_date: 2013-10-01T15:16:12Z [Term] id: FYPO:0002739 name: abnormal meiotic cell cycle process def: "A cellular process phenotype in which a cell does not execute a meiotic cell cycle process normally. A meiotic cell cycle process is any of the processes that form part of the meiotic cell cycle, and thereby ensures successive accurate and complete genome replication and meiotic chromosome segregation." [GO:0022402, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000052 ! abnormal meiotic cell cycle is_a: FYPO:0002734 ! abnormal cell cycle process created_by: midori creation_date: 2013-10-01T15:17:46Z [Term] id: FYPO:0002740 name: normal mitotic cell cycle phase def: "A cellular process phenotype in which a cell proceeds normally through a specific mitotic cell cycle phase. A mitotic cell cycle phase is any of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GO:0022403, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000411 ! normal mitotic cell cycle is_a: FYPO:0003833 ! normal cell cycle phase created_by: midori creation_date: 2013-10-01T16:02:38Z [Term] id: FYPO:0002741 name: normal mitotic cell cycle process def: "A cellular process phenotype in which a cell executes a mitotic cell cycle process normally (i.e. indistinguishably from wild type). A mitotic cell cycle process is any of the processes that form part of the mitotic cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation." [GO:1903047, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000411 ! normal mitotic cell cycle is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2013-10-01T16:03:12Z [Term] id: FYPO:0002742 name: increased level of iron transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Iron transport RNAs are transcribed from genes whose products are involved in iron transport." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased iron transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of iron transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of iron transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of iron transport gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0004490 ! increased level of transport gene mRNA during vegetative growth created_by: midori creation_date: 2013-10-01T16:48:00Z [Term] id: FYPO:0002743 name: increased level of amino acid metabolism gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid metabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid metabolism RNAs are transcribed from genes whose products are involved in metabolism of one or more amino acids." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased amino acid metabolism gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of amino acid metabolism gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of amino acid metabolism gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of amino acid metabolism gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-10-01T16:50:06Z [Term] id: FYPO:0002744 name: increased level of amino acid transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid transport RNAs are transcribed from genes whose products are involved in amino acid transport." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased amino acid transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of amino acid transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of amino acid transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of amino acid transport gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0004490 ! increased level of transport gene mRNA during vegetative growth created_by: midori creation_date: 2013-10-01T16:50:41Z [Term] id: FYPO:0002745 name: normal cellular proline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-proline level" EXACT [PomBase:mah] synonym: "normal cellular proline level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular proline level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of proline in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-10-03T13:12:08Z [Term] id: FYPO:0002746 name: normal cellular valine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-valine level" EXACT [PomBase:mah] synonym: "normal cellular valine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular valine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of valine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-10-03T13:13:20Z [Term] id: FYPO:0002747 name: normal cellular lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-lysine level" EXACT [PomBase:mah] synonym: "normal cellular lysine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular lysine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of lysine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2013-10-03T13:15:20Z [Term] id: FYPO:0002748 name: decreased cellular alanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular alanine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular alanine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-alanine level" EXACT [PomBase:mah] synonym: "decreased level of alanine in cell" EXACT [PomBase:mah] synonym: "reduced cellular alanine level" EXACT [PomBase:mah] synonym: "reduced level of alanine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-10-03T13:21:32Z [Term] id: FYPO:0002749 name: decreased cellular asparagine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular asparagine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular asparagine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-asparagine level" EXACT [PomBase:mah] synonym: "decreased level of asparagine in cell" EXACT [PomBase:mah] synonym: "reduced cellular asparagine level" EXACT [PomBase:mah] synonym: "reduced level of asparagine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-10-03T13:22:39Z [Term] id: FYPO:0002750 name: abnormal sulfate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sulfate ions into the cell is abnormal." [PomBase:mah] synonym: "abnormal sulfate import across plasma membrane" EXACT [GO:1902434] synonym: "abnormal sulfate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal sulfate import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sulfate import into cell" EXACT [PomBase:al] synonym: "abnormal sulfate ion import" EXACT [PomBase:mah] synonym: "abnormal sulfate uptake" EXACT [PomBase:mah] synonym: "abnormal sulphate import" EXACT [PomBase:mah] synonym: "abnormal sulphate ion import" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2013-10-03T13:39:22Z [Term] id: FYPO:0002751 name: decreased sulfate import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sulfate ions into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased sulfate import across plasma membrane" EXACT [GO:1902434] synonym: "decreased sulfate import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased sulfate import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sulfate import into cell" EXACT [PomBase:al] synonym: "decreased sulfate ion import" EXACT [PomBase:mah] synonym: "decreased sulfate uptake" EXACT [PomBase:mah] synonym: "decreased sulphate import" EXACT [PomBase:mah] synonym: "decreased sulphate ion import" EXACT [PomBase:mah] synonym: "reduced sulfate import" EXACT [PomBase:mah] is_a: FYPO:0002750 ! abnormal sulfate import created_by: midori creation_date: 2013-10-03T13:39:38Z [Term] id: FYPO:0002752 name: abolished cell population growth on methionine sulfur source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-methionine as the sole sulfur source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with methionine as the sulfur source, but does grow using a different sulfur source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished cell population growth on methionine sulphur source" EXACT [PomBase:mah] synonym: "abolished growth on methionine sulfur source" BROAD [PomBase:mah] synonym: "abolished methionine utilization" RELATED [PomBase:mah] synonym: "abolished vegetative cell population growth on methionine sulfur source" EXACT [PomBase:mah] synonym: "cell population growth on methionine sulfur source abolished" EXACT [PomBase:mah] synonym: "inability to utilize methionine as sole sulphur source" RELATED [PomBase:al] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2013-10-03T14:14:42Z [Term] id: FYPO:0002753 name: abolished cell population growth on sulfate sulfur source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing sulfate ions as the sole sulfur source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with sulfate as the sulfur source, but does grow using a different sulfur source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished cell population growth on sulphate sulphur source" EXACT [PomBase:mah] synonym: "abolished growth on sulfate sulfur source" BROAD [PomBase:mah] synonym: "abolished sulfate utilization" RELATED [PomBase:mah] synonym: "abolished vegetative cell population growth on sulfate ion sulfur source" EXACT [PomBase:mah] synonym: "cell population growth on sulfate sulfur source abolished" EXACT [PomBase:mah] synonym: "inability to utilize sulphate as sole sulphur source" RELATED [PomBase:al] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2013-10-03T14:25:55Z [Term] id: FYPO:0002754 name: abnormal cysteine synthase activity def: "A molecular function phenotype in which the observed rate of cysteine synthase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-10-03T14:48:01Z [Term] id: FYPO:0002755 name: decreased cysteine synthase activity def: "A molecular function phenotype in which the observed rate of cysteine synthase activity is decreased." [PomBase:mah] synonym: "reduced cysteine synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002754 ! abnormal cysteine synthase activity created_by: midori creation_date: 2013-10-03T14:48:20Z [Term] id: FYPO:0002756 name: increased cysteine synthase activity def: "A molecular function phenotype in which the observed rate of cysteine synthase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002754 ! abnormal cysteine synthase activity created_by: midori creation_date: 2013-10-03T14:48:38Z [Term] id: FYPO:0002757 name: resistance to quinidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of quinidine than normal." [PomBase:mah] synonym: "resistance to quinidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to quinidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to quinidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-10-03T15:15:54Z [Term] id: FYPO:0002758 name: resistance to 4-nitroquinoline N-oxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 4-nitroquinoline N-oxide than normal." [PomBase:mah] synonym: "resistance to 4-nitroquinoline N-oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to 4-nitroquinoline N-oxide during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to 4-NQO" EXACT [PomBase:mah] synonym: "resistance to 4NQO" EXACT [PomBase:mah] synonym: "resistant to 4-nitroquinoline N-oxide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-10-03T15:16:56Z [Term] id: FYPO:0002759 name: abolished protein localization to pre-autophagosomal structure def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to pre-autophagosomal structure" EXACT [PomBase:mah] synonym: "abolished protein localization to PAS" EXACT [GO:0034497] synonym: "abolished protein localization to pre-autophagosomal structure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to pre-autophagosomal structure during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to pre-autophagosomal structure abolished" EXACT [PomBase:mah] is_a: FYPO:0002614 ! abnormal protein localization to pre-autophagosomal structure created_by: midori creation_date: 2013-10-03T15:39:50Z [Term] id: FYPO:0002760 name: short cytoplasmic microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are shorter than normal." [PomBase:mah] synonym: "short cytoplasmic microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short cytoplasmic microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0004088 ! abnormal cytoplasmic microtubules created_by: midori creation_date: 2013-10-03T15:37:54Z [Term] id: FYPO:0002761 name: abnormal microtubule bundle formation def: "A cellular process phenotype in which microtubule bundle formation, which normally results in a parallel arrangement of microtubules, is abnormal." [GO:0001578, PomBase:mah] synonym: "abnormal microtubule array formation" RELATED [PomBase:vw] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2013-10-03T15:53:48Z [Term] id: FYPO:0002762 name: inviable after spore germination, without cell division, spheroid cell def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type." [PomBase:mah] synonym: "inviable after spore germination, undivided spheroid cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, spheroid cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, spheroid cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, spheroid cell" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0002482 ! inviable spheroid vegetative cell created_by: midori creation_date: 2013-10-03T16:26:06Z [Term] id: FYPO:0002763 name: abnormal tRNA (guanine(9)-N(1))-methyltransferase activity def: "A molecular function phenotype in which the observed rate of tRNA (guanine(9)-N(1))-methyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-10-08T13:42:54Z [Term] id: FYPO:0002764 name: abolished tRNA (guanine(9)-N(1))-methyltransferase activity def: "A molecular function phenotype in which tRNA (guanine(9)-N(1))-methyltransferase activity is absent." [PomBase:mah] synonym: "tRNA (guanine(9)-N(1))-methyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002763 ! abnormal tRNA (guanine(9)-N(1))-methyltransferase activity created_by: midori creation_date: 2013-10-08T13:43:03Z [Term] id: FYPO:0002765 name: decreased tRNA (guanine(9)-N(1))-methyltransferase activity def: "A molecular function phenotype in which the observed rate of tRNA (guanine(9)-N(1))-methyltransferase activity is decreased." [PomBase:mah] synonym: "reduced tRNA (guanine(9)-N(1))-methyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002763 ! abnormal tRNA (guanine(9)-N(1))-methyltransferase activity created_by: midori creation_date: 2013-10-08T13:43:18Z [Term] id: FYPO:0002766 name: resistance to clotrimazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of clotrimazole than normal." [PomBase:mah] synonym: "resistance to clotrimazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to clotrimazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to clotrimazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-10-08T14:25:26Z [Term] id: FYPO:0002767 name: resistance to terbinafine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of terbinafine than normal." [PomBase:mah] synonym: "resistance to terbinafine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to terbinafine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to terbinafine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-10-08T14:26:19Z [Term] id: FYPO:0002768 name: decreased protein ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein ubiquitinylation during vegetative growth" EXACT [GO:0016567, PomBase:mah] synonym: "decreased protein ubiquitylation during vegetative growth" EXACT [GO:0016567, PomBase:mah] synonym: "reduced protein ubiquitination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000905 ! abnormal protein ubiquitination during vegetative growth is_a: FYPO:0007946 ! decreased protein ubiquitination created_by: midori creation_date: 2013-10-08T14:36:41Z [Term] id: FYPO:0002769 name: abnormal protein localization to spindle pole body def: "A cell phenotype in which the localization of a protein to the spindle pole body is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to spindle pole body" EXACT [PomBase:mah] synonym: "abnormal protein localization to SPB" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2013-10-10T15:20:35Z [Term] id: FYPO:0002770 name: decreased protein localization to spindle pole body def: "A cell phenotype in which the localization of a protein to the spindle pole body is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to spindle pole body" EXACT [PomBase:mah] synonym: "decreased protein localization to SPB" EXACT [PomBase:mah] synonym: "reduced protein localization to spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0002769 ! abnormal protein localization to spindle pole body created_by: midori creation_date: 2013-10-10T15:22:07Z [Term] id: FYPO:0002771 name: abnormal protein localization to meiotic spindle pole body def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to meiotic spindle pole body" EXACT [PomBase:mah] synonym: "abnormal protein localization to meiotic SPB" EXACT [PomBase:mah] is_a: FYPO:0002769 ! abnormal protein localization to spindle pole body is_a: FYPO:0003549 ! abnormal protein localization during meiosis created_by: midori creation_date: 2013-10-10T15:41:12Z [Term] id: FYPO:0002772 name: decreased protein localization to meiotic spindle pole body def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Use this term for cells in which in which the re-accumulation of some spindle pole body components does not occur at the onset of meiosis I. synonym: "decreased protein localisation to meiotic spindle pole body" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic SPB" EXACT [PomBase:mah] synonym: "reduced protein localization to meiotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0002770 ! decreased protein localization to spindle pole body is_a: FYPO:0002771 ! abnormal protein localization to meiotic spindle pole body created_by: midori creation_date: 2013-10-10T15:42:17Z [Term] id: FYPO:0002773 name: third meiotic division def: "A cellular process phenotype in which a cell undergoes an abnormal nuclear division after meiosis II is complete." [PMID:23628763, PomBase:mah] synonym: "meiosis III" RELATED [PMID:23628763] synonym: "meiosis termination defect" EXACT [PMID:23628763] synonym: "third meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2013-10-10T15:56:53Z [Term] id: FYPO:0002774 name: increased level of ubiquitinated protein in cell during vegetative growth def: "A cell phenotype in which the amount of ubiquitinated protein measured in the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider also annotating to 'increased protein ubiquitination' (FYPO:0002082) if the experiment directly assays the ubiquitination reaction(s). synonym: "increased accumulation of ubiquitinated protein in cell during vegetative growth" RELATED [PomBase:al] synonym: "increased level of ubiquitinated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased ubiquitinated protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2013-10-10T16:03:17Z [Term] id: FYPO:0002775 name: decreased level of sumoylated protein in cell def: "A cell phenotype in which the amount of sumoylated protein measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] synonym: "decreased accumulation of sumoylated protein in cell" RELATED [PomBase:mah] synonym: "decreased level of sumoylated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of sumoylated protein in cell during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sumoylated protein level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of sumoylated protein in cell" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2013-10-10T16:07:19Z [Term] id: FYPO:0002776 name: normal level of sumoylated protein in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sumoylated protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] synonym: "normal level of sumoylated protein during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of sumoylated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal sumoylated protein accumulation" RELATED [PomBase:mah] synonym: "normal sumoylated protein level" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2013-10-10T16:08:53Z [Term] id: FYPO:0002777 name: abnormal protein sumoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the sumoylation of one or more specific proteins, or of specific protein sites, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein sumolation during vegetative growth" EXACT [GO:0016925, PomBase:mah] synonym: "abnormal protein sumoylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2013-10-10T16:15:15Z [Term] id: FYPO:0002778 name: decreased protein sumoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of sumoylation of one or more specific proteins, or of specific protein sites, is decreased." [PomBase:mah] synonym: "decreased protein sumolation during vegetative growth" EXACT [GO:0016925, PomBase:mah] synonym: "decreased protein sumoylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein sumoylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002777 ! abnormal protein sumoylation during vegetative growth created_by: midori creation_date: 2013-10-10T16:15:25Z [Term] id: FYPO:0002779 name: abolished protein localization to nucleus, with protein mislocalized to cytoplasm, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization in nucleus, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [GO:0034504] synonym: "abolished protein localization to nucleus, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear exclusion, with protein mislocalized to cytoplasm, during vegetative growth" RELATED [PomBase:vw] synonym: "nuclear protein exclusion, with protein mislocalized to cytoplasm, during vegetative growth" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2013-10-10T16:32:09Z [Term] id: FYPO:0002780 name: decreased cellular reactive oxygen species level during vegetative growth def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased cellular reactive oxygen species accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased cellular reactive oxygen species level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular ROS accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased cellular ROS level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ROS accumulation during vegetative growth" RELATED [PomBase:al] synonym: "reduced cellular reactive oxygen species level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular ROS level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0002142 ! altered cellular reactive oxygen species level created_by: midori creation_date: 2013-10-10T16:38:51Z [Term] id: FYPO:0002781 name: increased transcription during cellular response to nitric oxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to nitric oxide. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased transcription during cellular response to nitric oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription during cellular response to nitric oxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription during cellular response to nitric oxide stress" RELATED [PomBase:al] synonym: "increased transcription during cellular response to NO during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2013-10-10T16:43:03Z [Term] id: FYPO:0002782 name: increased transcription during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to a salt stress. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased transcription during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2013-10-10T16:46:32Z [Term] id: FYPO:0002783 name: decreased transcription during cellular response to nitric oxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to nitric oxide. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "decreased transcription during cellular response to nitric oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription during cellular response to nitric oxide during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription during cellular response to nitric oxide stress" RELATED [PomBase:al] synonym: "reduced transcription during cellular response to nitric oxide" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2013-10-10T16:48:41Z [Term] id: FYPO:0002784 name: decreased transcription during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to a salt stress. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "decreased transcription during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2013-10-10T16:48:48Z [Term] id: FYPO:0002785 name: abolished riboflavin binding def: "A molecular function phenotype in which riboflavin binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "riboflavin binding abolished" EXACT [PomBase:mah] is_a: FYPO:0002388 ! abnormal riboflavin binding created_by: midori creation_date: 2013-10-16T11:29:42Z [Term] id: FYPO:0002786 name: decreased riboflavin binding def: "A molecular function phenotype in which occurrence of riboflavin binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced riboflavin binding" EXACT [PomBase:mah] is_a: FYPO:0002388 ! abnormal riboflavin binding created_by: midori creation_date: 2013-10-16T11:29:54Z [Term] id: FYPO:0002787 name: small vacuoles def: "A cell phenotype in which vacuoles are smaller than normal." [PomBase:mah] synonym: "decreased vacuole size" EXACT [PomBase:vw] synonym: "reduced vacuole size" EXACT [PomBase:vw] is_a: FYPO:0002257 ! abnormal vacuolar morphology is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2013-10-16T11:45:57Z [Term] id: FYPO:0002788 name: small vacuoles during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are smaller than normal." [PomBase:mah] synonym: "decreased vacuole size during vegetative growth" EXACT [PomBase:vw] synonym: "reduced vacuole size during vegetative growth" EXACT [PomBase:vw] synonym: "small vacuoles during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000368 ! abnormal vacuolar morphology during vegetative growth is_a: FYPO:0002787 ! small vacuoles created_by: midori creation_date: 2013-10-16T11:46:21Z [Term] id: FYPO:0002789 name: small vacuoles during stationary phase def: "A cell phenotype observed when the population in which the cell is found is in stationary phase in which vacuoles are smaller than normal." [PomBase:mah] synonym: "decreased vacuole size during stationary phase" EXACT [PomBase:vw] synonym: "reduced vacuole size during stationary phase" EXACT [PomBase:vw] is_a: FYPO:0002787 ! small vacuoles created_by: midori creation_date: 2013-10-16T11:46:42Z [Term] id: FYPO:0002790 name: vacuoles present in increased numbers def: "A physical cellular phenotype in which cells contain more vacuoles than normal." [PomBase:mah] synonym: "additional vacuoles present" EXACT [PomBase:mah] synonym: "extra vacuoles" EXACT [PomBase:mah] synonym: "vacuoles present in greater numbers" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2013-10-16T15:31:27Z [Term] id: FYPO:0002791 name: small vacuoles present in increased numbers during stationary phase def: "A cell phenotype in which a cell contains more, but smaller, vacuoles than normal when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "fragmented vacuoles during stationary phase" RELATED [PomBase:mah] synonym: "small vacuoles present in greater numbers during stationary phase" EXACT [PomBase:mah] synonym: "vacuoles present in increased numbers, with decreased vacuole size, during stationary phase" EXACT [PomBase:vw] is_a: FYPO:0002258 ! small vacuoles present in increased numbers is_a: FYPO:0002789 ! small vacuoles during stationary phase relationship: has_part FYPO:0002789 ! small vacuoles during stationary phase relationship: has_part FYPO:0006053 ! lipid droplets present in spore cytoplasm in decreased numbers, mislocalized to ascus epiplasm created_by: midori creation_date: 2013-10-16T15:41:48Z [Term] id: FYPO:0002792 name: small vacuoles present in increased numbers during cellular hypotonic response def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more, but smaller, vacuoles than normal during a cellular response to a hypotonic environment." [PomBase:mah] synonym: "fragmented vacuoles during cellular hypotonic response" RELATED [PomBase:mah] synonym: "small vacuoles present in greater numbers during cellular hypotonic response" EXACT [PomBase:mah] synonym: "small vacuoles present in increased numbers during cellular hypotonic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small vacuoles present in increased numbers during cellular hypotonic response during vegetative growth" EXACT [PomBase:mah] synonym: "small vacuoles present in increased numbers during hypotonic stress" EXACT [PomBase:al] synonym: "vacuoles present in increased numbers, with decreased vacuole size, during cellular hypotonic response" EXACT [PomBase:vw] is_a: FYPO:0002258 ! small vacuoles present in increased numbers relationship: has_part FYPO:0006053 ! lipid droplets present in spore cytoplasm in decreased numbers, mislocalized to ascus epiplasm relationship: output_of FYPO:0004483 ! abnormal vacuole fusion during cellular hypotonic response created_by: midori creation_date: 2013-10-16T15:44:28Z [Term] id: FYPO:0002793 name: vacuoles present in decreased numbers during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer vacuoles than normal." [PomBase:mah] synonym: "decreased level of vacuoles during vegetative growth" RELATED [PomBase:al] synonym: "fewer vacuoles present during vegetative growth" EXACT [PomBase:mah] synonym: "vacuoles present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vacuoles present in reduced numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2013-10-16T15:53:47Z [Term] id: FYPO:0002794 name: abnormal vacuole def: "A physical cellular phenotype in which the number, distribution, or morphology of all or part of the vacuole(s) is abnormal." [PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in a physically abnormal cytoskeleton. synonym: "abnormal vacuole physical object quality" EXACT [PomBase:mah] synonym: "abnormal vacuoles" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2013-10-16T15:54:06Z [Term] id: FYPO:0002795 name: large vacuoles present in decreased numbers during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, vacuoles than normal." [PomBase:mah] synonym: "enlarged vacuoles present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "large vacuoles present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large vacuoles present in reduced numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000123 ! large vacuoles during vegetative growth is_a: FYPO:0002793 ! vacuoles present in decreased numbers during vegetative growth created_by: midori creation_date: 2013-10-16T16:02:59Z [Term] id: FYPO:0002796 name: abnormal protein degradation during nitrogen starvation def: "A cellular process phenotype in which protein degradation is abnormal when the cell is subject to nitrogen starvation. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein breakdown during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolic process during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolism during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein degradation during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal protein degradation during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002275 ! abnormal protein degradation created_by: midori creation_date: 2013-10-16T16:11:43Z [Term] id: FYPO:0002797 name: decreased protein degradation def: "A cellular process phenotype in which the occurrence of protein degradation is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism" EXACT [GO:0030163, PomBase:mah] synonym: "reduced protein degradation" EXACT [PomBase:mah] is_a: FYPO:0002275 ! abnormal protein degradation relationship: has_output FYPO:0000836 ! increased protein level created_by: midori creation_date: 2013-10-16T16:12:20Z [Term] id: FYPO:0002798 name: decreased protein degradation during nitrogen starvation def: "A cellular process phenotype in which the occurrence of protein degradation is decreased when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein catabolic process during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased protein degradation during nitrogen deprivation" EXACT [PomBase:vw] synonym: "reduced protein degradation during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002796 ! abnormal protein degradation during nitrogen starvation is_a: FYPO:0002797 ! decreased protein degradation relationship: has_output FYPO:0001219 ! increased protein level during cellular response to nitrogen starvation created_by: midori creation_date: 2013-10-16T16:12:34Z [Term] id: FYPO:0002799 name: normal protein degradation def: "A cellular process phenotype in which protein degradation is normal (i.e. indistinguishable from wild type). Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein breakdown" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism" EXACT [GO:0030163, PomBase:mah] is_a: FYPO:0004849 ! normal protein metabolic process created_by: midori creation_date: 2013-10-16T16:17:41Z [Term] id: FYPO:0002800 name: normal protein degradation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type). Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein breakdown during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein degradation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process during vegetative growth is_a: FYPO:0002799 ! normal protein degradation created_by: midori creation_date: 2013-10-16T16:23:50Z [Term] id: FYPO:0002801 name: normal protein degradation during nitrogen starvation def: "A cellular process phenotype in which protein degradation is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein breakdown during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism during nitrogen starvation" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein degradation during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal protein degradation during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002799 ! normal protein degradation created_by: midori creation_date: 2013-10-16T16:24:11Z [Term] id: FYPO:0002802 name: nucleus mislocalized to cell cortex during nitrogen starvation def: "A physical cellular phenotype in which a cell has a nucleus in an abnormal location at the cell cortex when the cell is subject to nitrogen starvation. The normal location is at the midpoint of the long axis of the cell." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "nuclear displacement to cell cortex during nitrogen starvation" EXACT [PomBase:vw] synonym: "nucleus displaced to cell cortex during nitrogen starvation" EXACT [PomBase:vw] synonym: "nucleus mislocalised to cell cortex during nitrogen starvation" EXACT [PomBase:mah] synonym: "nucleus mislocalized to cell cortex during nitrogen depletion" EXACT [PomBase:vw] synonym: "nucleus mislocalized to cell cortex during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002069 ! mislocalized nucleus created_by: midori creation_date: 2013-10-16T16:33:25Z [Term] id: FYPO:0002803 name: abnormal vacuole organization def: "A cellular process phenotype in which vacuole organization is abnormal. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GO:0007033, PomBase:mah] comment: Consider annotating to 'abnormal vacuolar morphology' (FYPO:0002257), but note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuolar organisation" EXACT [PomBase:vw] synonym: "abnormal vacuolar organization" EXACT [PomBase:vw] synonym: "abnormal vacuole organisation" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2013-10-16T16:35:40Z [Term] id: FYPO:0002804 name: abnormal vacuole organization during nitrogen starvation def: "A cellular process phenotype in which vacuole organization is abnormal when the cell is subject to nitrogen starvation. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GO:0007033, PomBase:mah] comment: Consider annotating to 'abnormal vacuolar morphology' (FYPO:0002257), but note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal vacuolar organisation during nitrogen starvation" EXACT [PomBase:vw] synonym: "abnormal vacuolar organization during nitrogen starvation" EXACT [PomBase:vw] synonym: "abnormal vacuole organisation during nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal vacuole organization during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal vacuole organization during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0002803 ! abnormal vacuole organization created_by: midori creation_date: 2013-10-16T16:37:13Z [Term] id: FYPO:0002805 name: normal sodium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sodium ion import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal sodium import across plasma membrane" EXACT [GO:0098719] synonym: "normal sodium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal sodium import during vegetative growth" EXACT [PomBase:mah] synonym: "normal sodium import into cell" EXACT [PomBase:al] synonym: "normal sodium ion import into cell" EXACT [PomBase:mah] synonym: "normal sodium uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2013-10-22T14:47:17Z [Term] id: FYPO:0002806 name: sensitive to arsenate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to arsenate ions. Cells stop growing (and may die) at a concentration of arsenate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to arsenate" EXACT [PomBase:mah] synonym: "sensitive to arsenate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to arsenate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to arsenate ions" EXACT [PomBase:mah] is_a: FYPO:0000093 ! sensitive to arsenic created_by: midori creation_date: 2013-10-22T14:58:17Z [Term] id: FYPO:0002807 name: normal growth on arsenate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing arsenate ions." [PomBase:mah] synonym: "normal cell population growth in presence of arsenate" EXACT [PomBase:mah] synonym: "normal cell population growth on arsenate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on arsenate ion" EXACT [PomBase:mah] synonym: "normal cellular response to arsenate" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on arsenate ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on arsenate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-10-22T15:00:18Z [Term] id: FYPO:0002808 name: abnormal 6,7-dimethyl-8-ribityllumazine synthase activity def: "A molecular function phenotype in which the observed rate of 6,7-dimethyl-8-ribityllumazine synthase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-10-22T15:09:52Z [Term] id: FYPO:0002809 name: decreased 6,7-dimethyl-8-ribityllumazine synthase activity def: "A molecular function phenotype in which the observed rate of 6,7-dimethyl-8-ribityllumazine synthase activity is decreased." [PomBase:mah] synonym: "reduced 6,7-dimethyl-8-ribityllumazine synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002808 ! abnormal 6,7-dimethyl-8-ribityllumazine synthase activity created_by: midori creation_date: 2013-10-22T15:09:58Z [Term] id: FYPO:0002810 name: normal septation index in stationary phase def: "A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type) in a population in stationary phase. The septation index is the proportion of the population undergoing septation at any given time." [PomBase:mah, PomBase:vw] synonym: "normal septation in stationary phase" RELATED [PomBase:mah] synonym: "normal septation index during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0001903 ! normal septation index created_by: midori creation_date: 2013-10-22T15:24:17Z [Term] id: FYPO:0002811 name: sensitive to non-ionic osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a non-ionic osmotic stress." [PomBase:mah] comment: Consider also annotating to 'sensitive to sorbitol' (FYPO:0000112) if sorbitol is used to cause osmotic stress. synonym: "decreased growth during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] synonym: "hypersensitive to non-ionic osmotic stress" EXACT [PomBase:mah] synonym: "sensitive to non-ionic osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to non-ionic osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress created_by: midori creation_date: 2013-10-22T15:47:09Z [Term] id: FYPO:0002812 name: decreased cellular glycerol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glycerol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular glycerol level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glycerol accumulation" RELATED [PomBase:al] synonym: "reduced cellular glycerol level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-10-22T16:05:42Z [Term] id: FYPO:0002813 name: decreased cellular glycerol level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to salt stress is lower than normal." [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glycerol accumulation during cellular response to salt stress" RELATED [PomBase:al] synonym: "reduced cellular glycerol level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0002812 ! decreased cellular glycerol level created_by: midori creation_date: 2013-10-22T16:06:13Z [Term] id: FYPO:0002814 name: abnormal protein localization to cell surface def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is abnormal. The cell surface refers to the external part of the cell wall and/or plasma membrane." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell surface and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell surface" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell surface during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to cell surface during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2013-10-22T16:10:52Z [Term] id: FYPO:0002815 name: abolished protein localization to cell surface def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is abolished. The cell surface refers to the external part of the cell wall and/or plasma membrane." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell surface" EXACT [PomBase:mah] synonym: "abolished protein localization to cell surface during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cell surface during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cell surface abolished" EXACT [PomBase:mah] is_a: FYPO:0002814 ! abnormal protein localization to cell surface created_by: midori creation_date: 2013-10-22T16:11:09Z [Term] id: FYPO:0002816 name: inviable after spore germination, without cell division, multinucleate cell with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and in which the nucleus divides at least once to produce a multinucleate cell. The cell does not divide, and eventually dies." [PomBase:mah] synonym: "inviable germinated spore, without cell division, multinucleate cell with elongated germ tube" EXACT [PomBase:mah] synonym: "inviable multinucleate germinated spore with elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, multinucleate cell with elongated germ tube" EXACT [PomBase:mah] synonym: "multinucleate after spore germination with elongated germ tube" EXACT [PomBase:vw] is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube created_by: midori creation_date: 2013-10-29T12:17:06Z [Term] id: FYPO:0002817 name: abnormally arrested meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division is arrested under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormal cell cycle arrest in meiosis I" EXACT [PomBase:mah] synonym: "abnormally arrested first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000475 ! abnormally arrested meiosis created_by: midori creation_date: 2013-10-29T12:52:39Z [Term] id: FYPO:0002818 name: microtubule bundles present in decreased numbers def: "A physical cellular phenotype in which cells contain fewer microtubule bundles than normal." [PomBase:mah] synonym: "decreased level of MT bundles" EXACT [PomBase:mah] synonym: "decreased microtubule bundling" RELATED [PomBase:vw] synonym: "microtubule arrays present in decreased numbers" RELATED [PomBase:vw] synonym: "microtubule bundles present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2013-11-04T12:25:29Z [Term] id: FYPO:0002819 name: increased histone H3-K9 acetylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in telomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K9 acetylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 acetylation at telomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9 acetylation at telomere during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "increased telomeric histone H3K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2013-11-04T12:36:50Z [Term] id: FYPO:0002820 name: abolished histone H3-K9 methylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in telomeric regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 methylation at telomere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished histone H3-K9 methylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 methylation at telomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me at telomere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished histone lysine H3 K9 methylation at telomere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished telomeric histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 methylation abolished at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 methylation absent at telomere during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0002566 ! abolished histone H3-K9 methylation during vegetative growth is_a: FYPO:0007375 ! abnormal histone methylation at telomere during vegetative growth created_by: midori creation_date: 2013-11-04T12:47:19Z [Term] id: FYPO:0002821 name: decreased protein localization to mitotic spindle pole body during interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during interphase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle pole body during interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic SPB during interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle pole body during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle pole body during interphase" EXACT [PomBase:mah] is_a: FYPO:0000940 ! decreased protein localization to mitotic spindle pole body created_by: midori creation_date: 2013-11-04T13:11:14Z [Term] id: FYPO:0002822 name: decreased protein localization to mitotic spindle pole body during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle pole body during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic SPB during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle pole body during M-phase" RELATED [PomBase:vw] synonym: "decreased protein localization to mitotic spindle pole body during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein localization to mitotic spindle pole body during mitotic nuclear division" EXACT [GO:0140014] synonym: "decreased protein localization to spindle pole body during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle pole body during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000940 ! decreased protein localization to mitotic spindle pole body created_by: midori creation_date: 2013-11-04T13:12:56Z [Term] id: FYPO:0002823 name: abolished protein localization to mitotic spindle pole body during interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body does not occur during interphase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle pole body during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from mitotic spindle pole body during interphase" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle pole body abolished during interphase" EXACT [PomBase:mah] synonym: "protein localization to mitotic SPB abolished during interphase" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle pole body abolished during interphase" EXACT [PomBase:mah] synonym: "protein localization to spindle pole body abolished during interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000941 ! abolished protein localization to mitotic spindle pole body created_by: midori creation_date: 2013-11-04T13:14:32Z [Term] id: FYPO:0002824 name: abnormal protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "abnormal protein localization to mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to spindle during mitosis" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0007863 ! abnormal protein localization to spindle created_by: midori creation_date: 2013-11-04T13:17:20Z [Term] id: FYPO:0002825 name: decreased protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to spindle during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle" EXACT [PomBase:mah] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2013-11-04T13:17:33Z [Term] id: FYPO:0002826 name: normal gamma-tubulin complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gamma-tubulin complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal gamma-tubulin complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal gamma-tubulin complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2013-11-04T13:25:12Z [Term] id: FYPO:0002827 name: decreased chromatin silencing at silent mating-type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased chromatin silencing at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "reduced chromatin silencing at silent mating-type cassette" EXACT [PomBase:mah] is_a: FYPO:0000156 ! abnormal chromatin silencing at silent mating-type cassette is_a: FYPO:0002353 ! decreased chromatin silencing created_by: midori creation_date: 2013-11-04T14:46:08Z [Term] id: FYPO:0002828 name: constitutive protein kinase activity def: "A regulation phenotype in which the basal activity of a protein kinase is increased relative to normal. Basal protein kinase activity is the activity observed in the absence of a regulator. Abnormally elevated basal activity may or may not reach the levels observed in the normal activated state." [PomBase:al, PomBase:mah] synonym: "constitutive protein kinase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "constitutive protein kinase activity during vegetative growth" EXACT [PomBase:mah] synonym: "constitutively active protein kinase" RELATED [PomBase:mah] is_a: FYPO:0000683 ! constitutive catalytic activity created_by: midori creation_date: 2013-11-04T14:49:21Z [Term] id: FYPO:0002829 name: decreased cellular phytochelatin level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular cadystin level" EXACT [PomBase:mah] synonym: "decreased cellular phytochelatin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phytochelatin level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased phytochelatin accumulation" RELATED [PomBase:al] synonym: "reduced cellular phytochelatin level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-11-04T15:38:55Z [Term] id: FYPO:0002830 name: delayed onset of protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein/peptide phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000775 ! abnormal protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-11-04T15:41:33Z [Term] id: FYPO:0002831 name: delayed onset of protein phosphorylation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "delayed onset of protein phosphorylation during mitotic M-phase" RELATED [PomBase:vw] synonym: "delayed onset of protein/peptide phosphorylation during mitosis" EXACT [PomBase:mah] synonym: "delayed protein phosphorylation during mitosis" EXACT [PomBase:mah] is_a: FYPO:0002830 ! delayed onset of protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-11-04T15:43:06Z [Term] id: FYPO:0002833 name: decreased polyuridylation-dependent decapping of nuclear-transcribed mRNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of polyuridylation-dependent decapping of nuclear-transcribed mRNA is decreased. All RNA decapping may be decreased, or one or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "decreased poly(U)-dependent decapping of nuclear-transcribed mRNA" EXACT [PomBase:vw] synonym: "decreased polyuridylation-dependent decapping of nuclear-transcribed mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased polyuridylation-dependent decapping of nuclear-transcribed mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased uridylation-dependent decapping of nuclear-transcribed mRNA" BROAD [GO:0036450] synonym: "reduced polyuridylation-dependent decapping of nuclear-transcribed mRNA" EXACT [PomBase:mah] is_a: FYPO:0002038 ! abnormal deadenylation-independent decapping of nuclear-transcribed mRNA created_by: midori creation_date: 2013-11-04T15:52:41Z [Term] id: FYPO:0002834 name: decreased chromatin silencing at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "decreased chromatin silencing at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased heterochromatin silencing at centromere" RELATED [PomBase:mah] synonym: "reduced chromatin silencing at centromere" EXACT [PomBase:mah] is_a: FYPO:0000146 ! abnormal chromatin silencing at centromere is_a: FYPO:0002353 ! decreased chromatin silencing created_by: midori creation_date: 2013-11-05T14:24:37Z [Term] id: FYPO:0002835 name: centromeric outer repeat transcript-derived siRNA absent def: "An RNA metabolism phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are absent." [PMID:20211136, PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of RNA from the centromere outer repeat region. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'abnormal chromatin silencing at centromere outer repeat region' (FYPO:0002346). synonym: "centromere outer repeat transcript-derived siRNA absent" EXACT [PomBase:mah] synonym: "centromeric outer repeat transcript-derived siRNA absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "centromeric outer repeat transcript-derived siRNA absent during vegetative growth" EXACT [PomBase:mah] synonym: "centromeric outer repeat transcript-derived siRNA undetectable" EXACT [PomBase:mah] synonym: "siRNAs homologous to outer repeats absent" EXACT [PomBase:vw] synonym: "siRNAs homologous to outer repeats undetectable" EXACT [PomBase:mah] is_a: FYPO:0000273 ! centromeric outer repeat transcripts absent is_a: FYPO:0004201 ! decreased centromeric outer repeat transcript-derived siRNA level is_a: FYPO:0006076 ! siRNA absent from cell created_by: midori creation_date: 2013-11-05T14:44:13Z [Term] id: FYPO:0002836 name: increased centromeric outer repeat transcript-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are present at greater levels than normal." [PMID:20211136, PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of RNA from the centromere outer repeat region. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'decreased chromatin silencing at centromere outer repeat region' (FYPO:0003412). synonym: "increased accumulation of centromeric outer repeat transcript-derived siRNA" EXACT [PomBase:mah] synonym: "increased accumulation of siRNAs homologous to outer repeats" RELATED [PomBase:vw] synonym: "increased centromere outer repeat transcript-derived siRNA level" EXACT [PomBase:mah] synonym: "increased centromeric outer repeat transcript-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased centromeric outer repeat transcript-derived siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of centromeric outer repeat transcript-derived siRNA" EXACT [PomBase:mah] synonym: "increased level of siRNAs homologous to outer repeats" EXACT [PomBase:vw] is_a: FYPO:0000220 ! increased centromeric outer repeat transcript level is_a: FYPO:0004207 ! increased siRNA level created_by: midori creation_date: 2013-11-05T14:46:21Z [Term] id: FYPO:0002837 name: normal centromeric outer repeat transcript-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small interfering RNA transcripts derived from the centromere outer repeat region measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of RNA from the centromere outer repeat region. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. synonym: "normal accumulation of centromeric outer repeat transcript-derived siRNA" RELATED [PomBase:mah] synonym: "normal accumulation of centromeric outer repeat transcript-derived siRNA during vegetative growth" RELATED [PomBase:mah] synonym: "normal accumulation of siRNAs homologous to outer repeats" RELATED [PomBase:vw] synonym: "normal centromeric outer repeat transcript-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal centromeric outer repeat transcript-derived siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of siRNAs homologous to outer repeats" EXACT [PomBase:vw] is_a: FYPO:0002567 ! normal centromeric outer repeat transcript level created_by: midori creation_date: 2013-11-05T14:49:58Z [Term] id: FYPO:0002838 name: abnormal protein localization to chromosome during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the centromere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromosome during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromosome during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004996 ! abnormal protein localization to chromosome created_by: midori creation_date: 2013-11-05T15:32:17Z [Term] id: FYPO:0002839 name: decreased protein localization to chromosome during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromosome during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to chromosome during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002838 ! abnormal protein localization to chromosome during vegetative growth created_by: midori creation_date: 2013-11-05T15:33:34Z [Term] id: FYPO:0002840 name: increased protein localization to chromosome during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromosome during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromosome during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002838 ! abnormal protein localization to chromosome during vegetative growth created_by: midori creation_date: 2013-11-05T15:33:43Z [Term] id: FYPO:0002841 name: abolished protein localization to chromosome during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromosome during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to chromosome abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002838 ! abnormal protein localization to chromosome during vegetative growth created_by: midori creation_date: 2013-11-05T15:33:50Z [Term] id: FYPO:0002842 name: decreased protein localization to centromere outer repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere outer repeat regions of a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromere outer repeat" EXACT [PomBase:mah] synonym: "decreased protein localisation to centromeric outer repeat region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome, centric outer repeat region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centromeric outer repeat region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to pericentric region" RELATED [PomBase:mah] synonym: "decreased protein localization to pericentromeric region" RELATED [PomBase:mah] synonym: "reduced protein localization to centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0002839 ! decreased protein localization to chromosome during vegetative growth created_by: midori creation_date: 2013-11-05T15:39:52Z [Term] id: FYPO:0002843 name: protein mislocalized to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleoplasm is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleoplasm" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleoplasm" EXACT [PomBase:mah] synonym: "protein mislocalised to nucleoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to nucleoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth relationship: output_of FYPO:0002529 ! abnormal protein localization to nucleoplasm created_by: midori creation_date: 2013-11-05T15:59:55Z [Term] id: FYPO:0002844 name: obsolete inviable microcolony, swollen elongated septated cells def: "OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells which are septated, elongated, and have a larger than normal cell volume. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is redundant with annotating to the equivalent cell phenotype, with penetrance extensions where needed. synonym: "inviable microcolony, enlarged long septated vegetative cells" RELATED [PomBase:mah] synonym: "inviable microcolony, large elongated septated vegetative cells" RELATED [PomBase:vw] synonym: "inviable microcolony, swollen elongated septated vegetative cells" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2013-11-05T16:02:59Z [Term] id: FYPO:0002845 name: inviable swollen elongated septated vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and contains one or more septa. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] comment: The distinction between this phenotype and centrally constricted (dumbbell-shaped) cells (FYPO:0000779) is that swollen elongated cells do not have a constriction along the long axis. Swollen elongated cells may have a uniform diameter, or may be swollen only around the nucleus. synonym: "inviable enlarged elongated septated vegetative cell with enlarged nucleus" RELATED [PomBase:mah] synonym: "inviable large elongated septated vegetative cell" RELATED [PomBase:vw] synonym: "lethal; swollen elongated septated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002251 ! inviable swollen elongated vegetative cell is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology is_a: FYPO:0004750 ! elongated septated vegetative cell created_by: midori creation_date: 2013-11-05T16:06:04Z [Term] id: FYPO:0002846 name: obsolete inviable mixed population including spores, germinated spores and small cells def: "OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and small vegetative cells. The spheroid cells arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because a "mixed population" observation would be better represented as two or more separate phenotype annotations, each with penetrance specified. is_obsolete: true created_by: midori creation_date: 2013-11-05T16:59:57Z [Term] id: FYPO:0002847 name: decreased protein level in proteasome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the proteasome is lower than normal." [PMID:22906049, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the proteasome is decreased, altering the proteasome stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased proteasomal protein level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in proteasome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level in proteasome during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level in proteasome" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0005003 ! abnormal protein complex composition created_by: midori creation_date: 2013-11-08T11:53:44Z [Term] id: FYPO:0002848 name: T-shaped cell during recovery from stationary phase def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell population has been in stationary phase and is then placed in conditions that allow recovery." [PomBase:jh, PomBase:mah] comment: One distinction between T-shaped and other branched cells is that in T-shaped cells the new growth zone forms before NETO. synonym: "T-shaped cell during recovery from stationary phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "T-shaped cell during vegetative growth following stationary phase" EXACT [PomBase:mah] is_a: FYPO:0007379 ! T-shaped vegetative cell created_by: midori creation_date: 2013-11-08T12:07:19Z [Term] id: FYPO:0002849 name: curved cell during recovery from stationary phase def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved when the cell population has been in stationary phase and is then placed in conditions that allow recovery. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:jh, PomBase:mah] synonym: "comma-shaped cell during recovery from stationary phase" EXACT [PomBase:mah] synonym: "curved cell during recovery from stationary phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "curved cell during vegetative growth following stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000016 ! curved vegetative cell created_by: midori creation_date: 2013-11-08T12:12:46Z [Term] id: FYPO:0002850 name: normal cell morphology during recovery from stationary phase def: "A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure) when the cell population has been in stationary phase and is then placed in conditions that allow recovery." [PomBase:mah] is_a: FYPO:0001315 ! normal vegetative cell morphology created_by: midori creation_date: 2013-11-08T12:18:07Z [Term] id: FYPO:0002851 name: protein mislocalized to eisosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the eisosome is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the eisosome in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to eisosome" EXACT [PomBase:vw] synonym: "protein mislocalised to eisosome" EXACT [PomBase:mah] synonym: "protein mislocalised to eisosome during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to eisosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to eisosome during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2013-11-08T13:07:40Z [Term] id: FYPO:0002852 name: increased protein localization to cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to cell end during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2013-11-08T13:18:06Z [Term] id: FYPO:0002853 name: abnormal glutamate-cysteine ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-cysteine ligase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-11-08T13:33:31Z [Term] id: FYPO:0002854 name: abolished glutamate-cysteine ligase activity def: "A molecular function phenotype in which glutamate-cysteine ligase activity is absent." [PomBase:mah] synonym: "glutamate-cysteine ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002853 ! abnormal glutamate-cysteine ligase activity created_by: midori creation_date: 2013-11-08T13:33:38Z [Term] id: FYPO:0002855 name: decreased glutamate-cysteine ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-cysteine ligase activity is decreased." [PomBase:mah] synonym: "reduced glutamate-cysteine ligase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002853 ! abnormal glutamate-cysteine ligase activity created_by: midori creation_date: 2013-11-08T13:33:47Z [Term] id: FYPO:0002856 name: abnormal glutathione synthase activity def: "A molecular function phenotype in which the observed rate of glutathione synthase activity is abnormal." [PomBase:mah] synonym: "abnormal glutathione synthetase activity" EXACT [GO:0004363] synonym: "abnormal GSH synthase activity" EXACT [GO:0004363] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-11-29T14:34:56Z [Term] id: FYPO:0002857 name: abolished glutathione synthase activity def: "A molecular function phenotype in which glutathione synthase activity is absent." [PomBase:mah] synonym: "abolished glutathione synthetase activity" EXACT [GO:0004363] synonym: "abolished GSH synthase activity" EXACT [GO:0004363] synonym: "glutathione synthase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002856 ! abnormal glutathione synthase activity created_by: midori creation_date: 2012-11-29T14:35:04Z [Term] id: FYPO:0002858 name: increased (1->3)-beta-D-glucan level at cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-beta-D-glucan measured at the cell tip is greater than normal." [PMID:17581129, PMID:21652630, PomBase:mah] comment: This term can be used when increased Calcofluor White staining is observed at the cell tip, as Calcofluor White binds specifically to linear (1->3)-beta-D-glucans in fission yeast. synonym: "increased (1,3)beta-D-glucan level at cell tip" EXACT [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan accumulation at cell tip" RELATED [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan level at cell end" EXACT [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan level at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan level at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "increased 1,3-beta-D-glucan level at cell tip" EXACT [CHEBI:37671] synonym: "increased level of (1->3)-beta-D-glucan at cell tip" EXACT [PomBase:mah] synonym: "septal material present at cell tip" RELATED [PMID:21652630, PomBase:al] synonym: "septum material present at cell tip" RELATED [PMID:8978671, PomBase:al] is_a: FYPO:0007949 ! increased (1->3)-beta-D-glucan level created_by: midori creation_date: 2013-11-08T14:19:44Z [Term] id: FYPO:0002859 name: abolished protein localization to non-growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the non-growing cell tip is abolished. The new cell tip formed upon cell division does not grow until after new end take-off." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to non-growing cell tip" EXACT [PomBase:mah] synonym: "abolished protein localization to new cell end" RELATED [PomBase:mah] synonym: "abolished protein localization to new cell tip" RELATED [PomBase:mah] synonym: "abolished protein localization to new non-growing cell tip" EXACT [PomBase:mah] synonym: "abolished protein localization to non-growing cell end" EXACT [PomBase:mah] synonym: "abolished protein localization to non-growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to non-growing cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to non-growing cell tip abolished" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2013-11-11T15:28:40Z [Term] id: FYPO:0002860 name: abnormal poly(U) polymerase activity def: "A molecular function phenotype in which the observed rate of polynucleotide uridylyltransferase activity is abnormal." [PMID:17449726, PomBase:mah] synonym: "abnormal polynucleotide uridylyltransferase activity" EXACT [PMID:17449726, PomBase:vw] synonym: "abnormal RNA uridylyltransferase activity" EXACT [GO:0050265] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2013-11-14T11:33:47Z [Term] id: FYPO:0002861 name: decreased poly(U) polymerase activity def: "A molecular function phenotype in which the observed rate of polynucleotide uridylyltransferase (poly(U) polymerase) activity is decreased." [PMID:17449726, PomBase:mah] synonym: "decreased polynucleotide uridylyltransferase activity" EXACT [PMID:17449726, PomBase:vw] synonym: "decreased RNA uridylyltransferase activity" EXACT [GO:0050265] synonym: "reduced poly(U) polymerase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0002860 ! abnormal poly(U) polymerase activity created_by: midori creation_date: 2013-11-14T11:33:54Z [Term] id: FYPO:0002862 name: abnormal cell growth def: "A cellular process phenotype in which cell growth is abnormal. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present." [GO:0016049, PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the 'cell population growth' terms. is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2013-11-14T12:08:41Z [Term] id: FYPO:0002863 name: slow cell growth during recovery from nitrogen starvation def: "A cellular process phenotype in which cells elongate more slowly than normal when the cells are returned to nitrogen-rich medium following nitrogen starvation." [PomBase:al, PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the 'cell population growth' terms. synonym: "slow cell growth during recovery from nitrogen depletion" EXACT [PomBase:vw] synonym: "slow cell growth during recovery from nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0006820 ! abnormal cell growth rate created_by: midori creation_date: 2013-11-14T12:12:23Z [Term] id: FYPO:0002864 name: resistance to 5-fluoroorotic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-fluoroorotic acid than normal." [PomBase:mah] synonym: "resistance to 5-fluoroorotic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to 5-fluoroorotic acid during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to 5-FOA" EXACT [PomBase:al] synonym: "resistant to 5-fluoroorotic acid" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2013-11-14T12:30:17Z [Term] id: FYPO:0002865 name: sensitive to polypeptone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to polypeptone. Cells stop growing (and may die) at a concentration of polypeptone that allows wild type cells to grow. Polypeptone is a mixture of peptones made up of equal parts of pancreatic digest of casein and peptic digest of animal used in media." [http://www.bd.com/ds/productCenter/211910.asp, PomBase:mah] synonym: "hypersensitive to polypeptone" EXACT [PomBase:mah] synonym: "sensitive to polypeptone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to polypeptone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-11-14T12:31:56Z [Term] id: FYPO:0002866 name: sensitive to tryptone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tryptone. Cells stop growing (and may die) at a concentration of tryptone that allows wild type cells to grow. Tryptone is a mixture of peptides produced by digestion of casein with trypsin." [http://www.bd.com/ds/productCenter/211701.asp, PomBase:mah] synonym: "hypersensitive to tryptone" EXACT [PomBase:mah] synonym: "sensitive to tryptone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tryptone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-11-14T12:35:33Z [Term] id: FYPO:0002867 name: increased cellular OMP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of orotidine 5'-phosphate (orotidine monophosphate; OMP) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular OMP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular OMP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular orotidine 5'-(dihydrogen phosphate) level" EXACT [CHEBI:15842] synonym: "increased cellular orotidine monophosphate level" EXACT [PomBase:mah] synonym: "increased OMP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-11-14T13:46:17Z [Term] id: FYPO:0002868 name: increased cellular orotidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of orotidine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular orotidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular orotidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased orotidine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2013-11-14T13:48:06Z [Term] id: FYPO:0002869 name: decreased protein localization to cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell division site" EXACT [PomBase:mah] synonym: "decreased protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein recruitment to cell division site" RELATED [PomBase:vw] synonym: "reduced protein localization to cell division site" EXACT [PomBase:mah] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2013-11-14T14:02:17Z [Term] id: FYPO:0002870 name: increased protein localization to non-growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a non-growing cell tip is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to non-growing cell tip" EXACT [PomBase:mah] synonym: "increased protein localization to new non-growing cell tip" EXACT [PomBase:mah] synonym: "increased protein localization to non-growing cell end" EXACT [PomBase:mah] synonym: "increased protein localization to non-growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to non-growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004977 ! increased protein localization to new cell tip created_by: midori creation_date: 2013-11-14T14:04:12Z [Term] id: FYPO:0002871 name: decreased protein localization to growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a growing cell tip is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to growing cell tip" EXACT [PomBase:mah] synonym: "decreased protein localization to growing cell end" EXACT [PomBase:mah] synonym: "decreased protein localization to growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to growing cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to growing cell tip" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2013-11-14T14:04:54Z [Term] id: FYPO:0002872 name: abnormal endoplasmic reticulum localization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the endoplasmic reticulum (ER) is abnormal. In fission yeast, the ER is normally located in the cell cortex and tethered to the plasma membrane." [PMID:23041194, PomBase:mah] synonym: "abnormal endoplasmic reticulum localisation" EXACT [PomBase:mah] synonym: "abnormal endoplasmic reticulum localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal endoplasmic reticulum localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ER localization" EXACT [PomBase:mah] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2013-11-14T14:17:54Z [Term] id: FYPO:0002873 name: normal septum orientation def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in the normal orientation perpendicular the long axis of the cell." [PomBase:mah] synonym: "normal septum orientation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septum orientation during vegetative growth" EXACT [PomBase:mah] synonym: "normal septum position" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2013-11-14T14:31:54Z [Term] id: FYPO:0002874 name: premature protein localization to medial cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex begins earlier than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to medial cortex during vegetative growth" EXACT [PomBase:mah] synonym: "faster protein localization to medial cortex during vegetative growth" RELATED [PomBase:mah] synonym: "premature protein localisation to medial cortex during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "premature protein localization to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0000731 ! abnormal protein localization to medial cortex during vegetative growth created_by: midori creation_date: 2013-11-14T14:49:40Z [Term] id: FYPO:0002875 name: increased transcription def: "A cellular process phenotype in which transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'increased RNA level' (FYPO:0000825). is_a: FYPO:0005502 ! abnormal transcription is_a: FYPO:0006548 ! increased gene expression relationship: has_output FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2013-11-14T15:19:36Z [Term] id: FYPO:0002876 name: decreased transcription def: "A cellular process phenotype in which transcription occurs to a lower extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). synonym: "reduced transcription" EXACT [PomBase:mah] is_a: FYPO:0005502 ! abnormal transcription is_a: FYPO:0006549 ! decreased gene expression relationship: has_output FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2013-11-14T15:16:51Z [Term] id: FYPO:0002877 name: abolished transcription def: "A cellular process phenotype in which transcription does not occur. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "transcription abolished" EXACT [PomBase:mah] is_a: FYPO:0002876 ! decreased transcription created_by: midori creation_date: 2013-11-14T15:29:01Z [Term] id: FYPO:0002878 name: increased transcription during glucose starvation def: "A cellular process phenotype in which transcription occurs to a greater extent than normal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "increased transcription during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "increased transcription during glucose depletion" EXACT [PomBase:vw] synonym: "increased transcription during glucose deprivation" EXACT [PomBase:vw] synonym: "increased transcription during glucose limitation" RELATED [PomBase:mah] synonym: "increased transcription in response to glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0002875 ! increased transcription is_a: FYPO:0006354 ! abnormal transcription during glucose starvation created_by: midori creation_date: 2013-11-14T15:30:22Z [Term] id: FYPO:0002879 name: abolished transcription during glucose starvation def: "A cellular process phenotype in which transcription does not occur when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abolished glucose deprivation induced gene expression" RELATED [PomBase:vw] synonym: "abolished transcription during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "abolished transcription during glucose depletion" EXACT [PomBase:vw] synonym: "abolished transcription during glucose deprivation" EXACT [PomBase:vw] synonym: "abolished transcription during glucose limitation" RELATED [PomBase:mah] synonym: "abolished transcription during glucose starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished transcription during glucose starvation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished transcription in response to glucose starvation" EXACT [PomBase:vw] synonym: "transcription abolished during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0002877 ! abolished transcription is_a: FYPO:0003120 ! decreased transcription during glucose starvation created_by: midori creation_date: 2013-11-14T15:30:46Z [Term] id: FYPO:0002880 name: decreased transcription during glucose starvation and oxidative stress def: "A cellular process phenotype in which transcription occurs to a lower extent than normal when the cell is subject to glucose starvation and oxidative stress simultaneously. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased transcription during cellular response to glucose starvation and oxidative stress" EXACT [PomBase:mah] synonym: "decreased transcription during glucose depletion and oxidative stress" EXACT [PomBase:vw] synonym: "decreased transcription during glucose deprivation and oxidative stress" EXACT [PomBase:vw] synonym: "decreased transcription during glucose limitation and oxidative stress" EXACT [PomBase:mah] synonym: "decreased transcription in response to glucose starvation and oxidative stress" EXACT [PomBase:mah] synonym: "decreased transcription in response to glucose starvation during oxidative stress" EXACT [PomBase:vw] synonym: "reduced transcription during glucose starvation and oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0003120 ! decreased transcription during glucose starvation created_by: midori creation_date: 2013-11-14T15:39:02Z [Term] id: FYPO:0002881 name: increased transcription during glucose starvation and oxidative stress def: "A cellular process phenotype in which transcription occurs to a greater extent than normal when the cell is subject to glucose starvation and oxidative stress simultaneously. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "increased transcription during glucose depletion and oxidative stress" EXACT [PomBase:vw] synonym: "increased transcription during glucose deprivation and oxidative stress" EXACT [PomBase:vw] synonym: "increased transcription during glucose limitation and oxidative stress" EXACT [PomBase:mah] synonym: "increased transcription in response to glucose starvation and oxidative stress" EXACT [PomBase:mah] synonym: "increased transcription in response to glucose starvation during oxidative stress" EXACT [PomBase:vw] is_a: FYPO:0002878 ! increased transcription during glucose starvation created_by: midori creation_date: 2013-11-14T15:42:43Z [Term] id: FYPO:0002882 name: normal transcription def: "A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription, DNA-dependent" EXACT [GO:0006351] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0004847 ! transcription phenotype created_by: midori creation_date: 2013-11-14T15:45:53Z [Term] id: FYPO:0002883 name: normal transcription during glucose starvation def: "A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be measured." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal transcription during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "normal transcription during glucose depletion" EXACT [PomBase:vw] synonym: "normal transcription during glucose deprivation" EXACT [PomBase:vw] synonym: "normal transcription during glucose limitation" RELATED [PomBase:mah] synonym: "normal transcription in response to glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0002882 ! normal transcription created_by: midori creation_date: 2013-11-14T15:51:50Z [Term] id: FYPO:0002884 name: normal transcription during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to osmotic stress. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription in response to osmotic stress" EXACT [PomBase:vw] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2013-11-14T16:08:33Z [Term] id: FYPO:0002885 name: normal transcription during cellular response to oxidative stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to oxidative stress. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription during oxidative stress response" EXACT [PomBase:vw] synonym: "normal transcription in response to oxidative stress" EXACT [PomBase:vw] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2013-11-14T16:10:17Z [Term] id: FYPO:0002886 name: normal transcription during cellular response to heavy metal stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to heavy metal stress. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to heavy metal stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to heavy metal stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription in response to heavy metal stress" EXACT [PomBase:vw] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2013-11-14T16:10:54Z [Term] id: FYPO:0002887 name: normal protein localization to telomere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "normal protein localisation to telomere during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "normal protein localization to telomere during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-11-14T16:13:58Z [Term] id: FYPO:0002888 name: mitotic cell cycle arrest before cell separation def: "A cellular process phenotype in which the mitotic cell cycle is arrested after the septum has formed, but before cells have separated, under conditions where arrest does not normally occur." [PMID:8978671, PomBase:mah] synonym: "cell cycle arrest before cell separation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest before cell separation after cytokinesis" EXACT [GO:0000920] synonym: "mitotic cell cycle arrest before cell separation during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest before mitotic cytokinetic cell separation" EXACT [GO:0000920] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression created_by: midori creation_date: 2013-11-19T12:13:06Z [Term] id: FYPO:0002889 name: inviable elongated vegetative cell with abnormal septum def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains one or more abnormal septa." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated inviable cell with abnormal septum" EXACT [PomBase:mah] synonym: "inviable elongated abnormally septated vegetative cell" EXACT [PomBase:mah, PomBase:vw] synonym: "inviable elongated cell with abnormal septum during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with abnormal septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell with abnormal septum" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0002455 ! abnormal septum during vegetative growth relationship: has_part FYPO:0002455 ! abnormal septum during vegetative growth created_by: midori creation_date: 2013-11-19T12:47:35Z [Term] id: FYPO:0002890 name: abnormal horsetail nucleus morphology def: "A physical cellular phenotype in which the size, shape, or structure of the horsetail nucleus is abnormal. The horsetail nucleus forms during the rapid oscillatory movement at meiotic prophase I." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. Consider also annotating to 'abnormal horsetail movement' (FYPO:0000197). synonym: "abnormal horsetail nuclear morphology" EXACT [PomBase:mah] is_a: FYPO:0005651 ! abnormal nuclear morphology during meiosis I created_by: midori creation_date: 2013-11-19T12:50:32Z [Term] id: FYPO:0002891 name: normal chromatin organization during vegetative growth def: "A cellular process phenotype in which any process of chromatin organization is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] synonym: "normal chromatin organisation during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromatin organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0007940 ! normal chromatin organization created_by: midori creation_date: 2013-11-19T13:34:36Z [Term] id: FYPO:0002892 name: normal heterochromatin organization during vegetative growth def: "A cellular process phenotype in which any process of heterochromatin organization is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin." [GO:0070828, PomBase:mah] synonym: "normal heterochromatin organisation during vegetative growth" EXACT [PomBase:mah] synonym: "normal heterochromatin organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2013-11-19T13:35:34Z [Term] id: FYPO:0002893 name: decreased repression of transcription during cellular response to cAMP def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription from RNA polymerase II promoter occurs to a lower extent than normal during a cellular response to cAMP. Specific genes are more highly transcribed in the presence of cAMP in the mutant than in wild type." [PMID:22496451, PomBase:mah] synonym: "decreased negative regulation of transcription from RNA polymerase II promoter during cellular response to cAMP" EXACT [GO:0000122, PomBase:mah] synonym: "decreased repression of transcription during cellular response to cAMP during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased repression of transcription during cellular response to cAMP during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcriptional repression during cellular response to cAMP" EXACT [PomBase:mah] synonym: "reduced repression of transcription during cellular response to cAMP" EXACT [PomBase:mah] is_a: FYPO:0000624 ! abnormal negative regulation of transcription during vegetative growth created_by: midori creation_date: 2013-11-19T13:43:15Z [Term] id: FYPO:0002894 name: decreased transcription during cellular response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to calcium ions. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "decreased transcription during cellular response to calcium" EXACT [PomBase:mah] synonym: "decreased transcription during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription in response to calcium" EXACT [PomBase:mah] synonym: "reduced transcription during cellular response to calcium ion" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2013-11-19T14:11:53Z [Term] id: FYPO:0002895 name: increased transcription during cellular response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to calcium ions. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased transcription during cellular response to calcium" EXACT [PomBase:mah] synonym: "increased transcription during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription in response to calcium" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2013-11-19T14:14:49Z [Term] id: FYPO:0002896 name: normal transcription during cellular response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to calcium ions. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to calcium" EXACT [PomBase:mah] synonym: "normal transcription during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription in response to calcium" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2013-11-19T14:16:00Z [Term] id: FYPO:0002897 name: decreased protein phosphorylation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to a DNA damage stimulus." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-11-19T14:20:10Z [Term] id: FYPO:0002898 name: abolished protein phosphorylation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to a DNA damage stimulus." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-11-19T14:21:29Z [Term] id: FYPO:0002899 name: normal protein phosphorylation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to a DNA damage stimulus." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-11-19T14:22:49Z [Term] id: FYPO:0002900 name: abnormal mitotic DNA damage checkpoint during cellular response to UV def: "A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is abnormal when the cell is exposed to ultraviolet light. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage." [PomBase:mah] synonym: "abnormal DNA damage checkpoint during cellular response to UV during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic DNA damage checkpoint activation during cellular response to UV" EXACT [PomBase:al] synonym: "abnormal mitotic DNA damage checkpoint during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "abnormal mitotic DNA damage checkpoint during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal mitotic DNA damage checkpoint is_a: FYPO:0004254 ! abnormal mitotic cell cycle regulation during cellular response to UV created_by: midori creation_date: 2013-11-19T14:24:36Z [Term] id: FYPO:0002901 name: normal protein localization to kinetochore during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0005042 ! normal protein localization to kinetochore created_by: midori creation_date: 2013-11-19T16:42:18Z [Term] id: FYPO:0002902 name: decreased protein localization to kinetochore during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to kinetochore during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001268 ! abnormal protein localization to kinetochore during vegetative growth created_by: midori creation_date: 2013-11-19T16:43:34Z [Term] id: FYPO:0002903 name: viable pear-shaped vegetative cell def: "A cell morphology phenotype in which a cell is viable and shaped in the form of a pear in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PomBase:mah] synonym: "viable ice cream cone-shaped cell during vegetative growth" EXACT [PMID:2236039, PomBase:vw] synonym: "viable pear-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable pear-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001120 ! pear-shaped vegetative cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000020 ! pear-shaped cell created_by: midori creation_date: 2013-11-20T12:11:07Z [Term] id: FYPO:0002904 name: inviable pear-shaped vegetative cell def: "A cell morphology phenotype in which a cell is inviable and shaped in the form of a pear in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PomBase:mah] synonym: "inviable ice cream cone-shaped cell during vegetative growth" EXACT [PMID:2236039, PomBase:vw] synonym: "inviable pear-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable pear-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; pear-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001120 ! pear-shaped vegetative cell is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000020 ! pear-shaped cell created_by: midori creation_date: 2013-11-20T12:12:02Z [Term] id: FYPO:0002905 name: normal telomere maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is normal (i.e. indistinguishable from wild type)." [GO:0000723, PomBase:mah] synonym: "normal telomere maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal telomere maintenance during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2013-11-26T11:16:57Z [Term] id: FYPO:0002906 name: increased antisense primary transcript splicing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of antisense RNA primary transcripts is increased." [PomBase:mah] synonym: "increased antisense primary transcript RNA splicing" EXACT [PomBase:mah] synonym: "increased antisense primary transcript splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased antisense primary transcript splicing during vegetative growth" EXACT [PomBase:mah] synonym: "increased antisense primary transcript splicing, via transesterification reactions with bulged adenosine as nucleophile" EXACT [GO:0000377] is_a: FYPO:0002916 ! increased RNA splicing, via spliceosome created_by: midori creation_date: 2013-11-27T14:11:37Z [Term] id: FYPO:0002907 name: circularized chromosome during mitotic G1 phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomeres have fused, forming circular chromosomes, during G1 phase of the mitotic cell cycle." [PMID:23133674, PomBase:mah] synonym: "circular chromosomes during mitotic G1 phase" EXACT [PomBase:mah] synonym: "circularised chromosome during mitotic G1 phase" EXACT [PomBase:mah] synonym: "circularized chromosome during G1 during vegetative growth" EXACT [PomBase:mah] synonym: "fused telomeres during mitotic G1 phase" RELATED [PomBase:mah] synonym: "telomere end fusion during mitotic G1 phase" RELATED [PomBase:mah] synonym: "telomere fusion during mitotic G1 phase" RELATED [PomBase:mah] synonym: "telomeres fused during mitotic G1 phase" RELATED [PomBase:mah] is_a: FYPO:0002702 ! circularized chromosome created_by: midori creation_date: 2013-11-26T11:25:59Z [Term] id: FYPO:0002908 name: increased transcription at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal in telomeric regions. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased telomeric transcription during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from telomere during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000780 ! increased transcription during vegetative growth is_a: FYPO:0007420 ! abnormal transcription at telomere created_by: midori creation_date: 2013-11-26T11:29:03Z [Term] id: FYPO:0002909 name: decreased protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to chromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0006631 ! decreased protein localization to chromatin created_by: midori creation_date: 2013-11-26T11:46:41Z [Term] id: FYPO:0002910 name: decreased protein localization to chromatin at transcribed regions during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to transcribed regions of chromatin is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at transcribed regions during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at transcribed regions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to transcribed chromatin regions during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at transcribed regions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2013-11-26T11:59:17Z [Term] id: FYPO:0002911 name: inviable after spore germination, without cell division, with swollen elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal, and does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination with elongated swollen germ tube" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, swollen elongated cell" RELATED [PomBase:mah] synonym: "inviable following spore germination with swollen elongated germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore with swollen elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with swollen elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0002251 ! inviable swollen elongated vegetative cell is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape created_by: midori creation_date: 2013-11-26T12:14:08Z [Term] id: FYPO:0002912 name: inviable after spore germination, without cell division, elongated multinucleate cell def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, is elongated, and contains more than one nucleus." [PomBase:mah] synonym: "inviable after spore germination, multinucleate elongated cell" EXACT [PomBase:mah] synonym: "inviable after spore germination, undivided elongated multinucleate cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, elongated multinucleate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, elongated multinucleate cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, elongated multinucleate cell" EXACT [PomBase:mah] is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0004603 ! inviable after spore germination, without cell division, elongated cell created_by: midori creation_date: 2013-11-26T12:18:40Z [Term] id: FYPO:0002913 name: increased antisense RNA transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which antisense RNA transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased antisense RNA transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased antisense RNA transcription during vegetative growth" EXACT [PomBase:mah] synonym: "increased antisense transcription" EXACT [PomBase:mah] synonym: "increased antisense transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth relationship: has_output FYPO:0003557 ! increased antisense RNA level created_by: midori creation_date: 2013-11-26T12:31:14Z [Term] id: FYPO:0002914 name: increased intergenic transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal in intergenic regions. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased intergenic transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription at intergenic regions during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription from intergenic regions" EXACT [PomBase:al] synonym: "increased transcription from intergenic regions during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2013-11-26T12:45:48Z [Term] id: FYPO:0002915 name: abnormal RNA splicing, via spliceosome def: "A cellular process phenotype in which RNA splicing is abnormal. All RNA splicing may be abnormal, or one splicing of or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "abnormal RNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RNA splicing during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" EXACT [GO:0000377] is_a: FYPO:0000294 ! RNA metabolism phenotype created_by: midori creation_date: 2013-11-26T12:58:29Z [Term] id: FYPO:0002916 name: increased RNA splicing, via spliceosome def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA splicing is increased. All RNA splicing may be increased, or splicing of one or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "increased RNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA splicing during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" EXACT [GO:0000377] is_a: FYPO:0002915 ! abnormal RNA splicing, via spliceosome created_by: midori creation_date: 2013-11-26T13:00:00Z [Term] id: FYPO:0002917 name: abolished histone H3-K4 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished histone H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "abolished histone H3-K4 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K4me during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "abolished histone lysine H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "histone H3-K4 methylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K4 methylation absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth is_a: FYPO:0002565 ! abolished histone methylation during vegetative growth created_by: midori creation_date: 2013-11-26T13:51:37Z [Term] id: FYPO:0002918 name: abnormal histone H3-K36 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 36 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K36 methylation during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "abnormal histone H3-K36 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H3K36me during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "abnormal histone lysine H3 K36 methylation during vegetative growth" EXACT [GO:0010452, PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2013-11-26T13:54:30Z [Term] id: FYPO:0002919 name: abolished histone H3-K36 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 36 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K36 methylation during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "abolished histone H3-K36 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K36me during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "abolished histone lysine H3 K36 methylation during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "histone H3-K36 methylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 methylation absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002565 ! abolished histone methylation during vegetative growth is_a: FYPO:0002918 ! abnormal histone H3-K36 methylation during vegetative growth is_a: FYPO:0006869 ! abolished histone H3-K36 methylation created_by: midori creation_date: 2013-11-26T13:54:53Z [Term] id: FYPO:0002920 name: normal histone H3-K36 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 36 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K36 methylation during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone H3-K36 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K36me during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone lysine H3 K36 methylation during vegetative growth" EXACT [GO:0010452, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2013-11-26T13:54:30Z [Term] id: FYPO:0002921 name: abnormal histone ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone ubiquitination is abnormal." [PomBase:mah] synonym: "abnormal histone ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone ubiquitinylation during vegetative growth" EXACT [GO:0016574] synonym: "abnormal histone ubiquitylation during vegetative growth" EXACT [GO:0016574] is_a: FYPO:0000330 ! abnormal histone modification during vegetative growth created_by: midori creation_date: 2013-11-26T14:30:58Z [Term] id: FYPO:0002922 name: abolished histone H2B-K119 ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B does not occur. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PomBase:mah] synonym: "abolished histone H2B conserved C-terminal lysine ubiquitination during vegetative growth" EXACT [GO:0071894] synonym: "abolished histone H2B-K119 ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "histone H2B-K119 ubiquitination abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H2B-K119 ubiquitination absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0005607 ! abnormal histone H2B-K119 ubiquitination during vegetative growth created_by: midori creation_date: 2013-11-26T14:33:35Z [Term] id: FYPO:0002923 name: normal histone H2B-K119 ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is normal (i.e. indistinguishable from wild type). Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PomBase:mah] synonym: "normal histone H2B conserved C-terminal lysine ubiquitination during vegetative growth" EXACT [GO:0071894, PomBase:mah] synonym: "normal histone H2B-K119 ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002600 ! normal histone modification during vegetative growth created_by: midori creation_date: 2013-11-26T14:38:40Z [Term] id: FYPO:0002924 name: decreased cell population growth on maltose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing maltose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on maltose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on maltose carbon source" EXACT [PomBase:mah] synonym: "growth defects, growth inhibition in maltose-based medium" RELATED [PomBase:mah] synonym: "reduced cell growth on maltose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on maltose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2013-11-26T14:46:01Z [Term] id: FYPO:0002925 name: decreased protein localization to chromosome at CRE promoter def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CRE promoter in a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromosome at CRE promoter" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome at CRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromosome at CRE promoter during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to M26 site" EXACT [SO:0001843] synonym: "reduced protein localization to chromosome at CRE promoter" EXACT [PomBase:mah] is_a: FYPO:0002839 ! decreased protein localization to chromosome during vegetative growth created_by: midori creation_date: 2013-11-26T14:50:00Z [Term] id: FYPO:0002926 name: abolished poly(A) RNA binding def: "A molecular function phenotype in which an interaction between a protein and polyadenylated RNA (poly(A)RNA) does not occur. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "abolished adenosine recognition in polyA tail" NARROW [] synonym: "abolished polyA RNA binding" EXACT [PomBase:mah] synonym: "abolished polyadenylated RNA binding" EXACT [PomBase:mah] synonym: "abolished protein-poly(A) RNA interaction" EXACT [PomBase:mah] synonym: "poly(A) RNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0002132 ! abnormal protein-RNA interaction created_by: midori creation_date: 2013-11-27T15:14:30Z [Term] id: FYPO:0002927 name: decreased poly(A) RNA binding def: "A molecular function phenotype in which an interaction between a protein and a polyadenylated RNA (poly(A)RNA) is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "decreased polyA RNA binding" EXACT [PomBase:mah] synonym: "decreased polyadenylated RNA binding" EXACT [PomBase:mah] synonym: "decreased protein-poly(A) RNA interaction" EXACT [PomBase:mah] synonym: "reduced poly(A) RNA binding" EXACT [PomBase:mah] is_a: FYPO:0002134 ! decreased protein-RNA interaction created_by: midori creation_date: 2013-11-27T15:14:36Z [Term] id: FYPO:0002928 name: normal poly(A) tail length def: "A phenotype in which polyadenylated RNA molecules have poly(A) tails of normal (i.e. indistinguishable from wild type) length." [PMID:24081329, PomBase:mah] synonym: "normal polyA sequence length" EXACT [SO:0000610] synonym: "normal polyA tail length" EXACT [SO:0000610] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2013-11-27T15:54:51Z [Term] id: FYPO:0002929 name: abnormal poly(A) tail length def: "A phenotype in which polyadenylated RNA molecules have poly(A) tails of abnormal length." [PMID:24081329, PomBase:mah] synonym: "abnormal polyA sequence length" EXACT [SO:0000610] synonym: "abnormal polyA tail length" EXACT [SO:0000610] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2013-11-27T15:56:57Z [Term] id: FYPO:0002930 name: decreased poly(A) tail length def: "A phenotype in which polyadenylated RNA molecules have poly(A) tails of that are shorter than normal." [PomBase:mah] synonym: "decreased polyA sequence length" EXACT [SO:0000610] synonym: "decreased polyA tail length" EXACT [SO:0000610] synonym: "reduced poly(A) tail length" EXACT [PomBase:mah] synonym: "short poly(a) tails" EXACT [PomBase:mah] is_a: FYPO:0002929 ! abnormal poly(A) tail length created_by: midori creation_date: 2013-11-27T15:57:38Z [Term] id: FYPO:0002931 name: increased poly(A) tail length def: "A phenotype in which polyadenylated RNA molecules have poly(A) tails of that are longer than normal." [PomBase:mah] synonym: "increased polyA sequence length" EXACT [SO:0000610] synonym: "increased polyA tail length" EXACT [SO:0000610] synonym: "long poly(a) tails" EXACT [PomBase:mah] is_a: FYPO:0002929 ! abnormal poly(A) tail length created_by: midori creation_date: 2013-11-27T15:58:41Z [Term] id: FYPO:0002932 name: decreased mature snoRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snoRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature small nucleolar RNA level" EXACT [PomBase:mah] synonym: "decreased mature snoRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature snoRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature snoRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature snoRNA transcript level" BROAD [PomBase:vw] synonym: "decreased snoRNA level" BROAD [PomBase:mah] synonym: "reduced mature snoRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005998 ! altered snoRNA or precursor level created_by: midori creation_date: 2013-11-28T13:13:18Z [Term] id: FYPO:0002933 name: increased mature snoRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snoRNA measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mature small nucleolar RNA level" EXACT [PomBase:mah] synonym: "increased mature snoRNA accumulation" RELATED [PomBase:mah] synonym: "increased mature snoRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature snoRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature snoRNA transcript level" BROAD [PomBase:vw] synonym: "increased snoRNA level" BROAD [PomBase:mah] is_a: FYPO:0005998 ! altered snoRNA or precursor level created_by: midori creation_date: 2013-11-28T13:16:00Z [Term] id: FYPO:0002937 name: decreased pre-mRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased accumulation of pre-mRNA transcripts" RELATED [PomBase:vw] synonym: "decreased pre-mRNA accumulation" RELATED [PomBase:mah] synonym: "decreased pre-mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased pre-mRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pre-mRNA transcript level" EXACT [PomBase:vw] synonym: "reduced pre-mRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-11-28T14:38:47Z [Term] id: FYPO:0002939 name: normal nuclear mRNA catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process that degrades mRNA encoded in the nucleus is normal (i.e. indistinguishable from wild type)." [GO:0000956, PomBase:mah] synonym: "normal nuclear mRNA breakdown" EXACT [GO:0000956] synonym: "normal nuclear mRNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear mRNA catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear mRNA catabolism" EXACT [GO:0000956] synonym: "normal nuclear mRNA degradation" EXACT [GO:0000956] synonym: "normal nuclear-transcribed mRNA catabolic process" EXACT [GO:0000956] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2013-11-28T14:42:41Z [Term] id: FYPO:0002940 name: normal growth on micafungin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing micafungin." [PomBase:mah] synonym: "normal cell population growth in presence of micafungin" EXACT [PomBase:mah] synonym: "normal cell population growth on micafungin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to micafungin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on micafungin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2013-12-04T13:04:57Z [Term] id: FYPO:0002941 name: swollen spheroid cell def: "A cell morphology phenotype in which a cell is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] synonym: "enlarged spheroid cell" RELATED [PomBase:mah] synonym: "enlarged volume spheroid cell" EXACT [PomBase:mah] synonym: "large spheroid cell" RELATED [PomBase:vw] synonym: "spheroid cell with increased cell size" RELATED [PomBase:vw] synonym: "spheroid cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen rounded cell" EXACT [PomBase:mah] is_a: FYPO:0000025 ! swollen cell is_a: FYPO:0001955 ! spheroid cell created_by: midori creation_date: 2013-12-04T13:30:22Z [Term] id: FYPO:0002942 name: swollen spheroid cell during G0 def: "A cell morphology phenotype in which a cell is shaped in the form of a spheroid, and has a larger volume than normal, when the cell is in G0 phase. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] comment: Note that fission yeast cells can enter G0 as a result of either glucose starvation or nitrogen starvation, which can be specified in annotations using conditions. synonym: "enlarged spheroid cell during G0" RELATED [PomBase:mah] synonym: "enlarged volume spheroid cell during G0" EXACT [PomBase:mah] synonym: "large spheroid cell during G0" RELATED [PomBase:vw] synonym: "spheroid cell with increased cell size during G0" RELATED [PomBase:vw] synonym: "spheroid cell with increased cell volume during G0" EXACT [PomBase:mah] synonym: "swollen rounded cell during G0" EXACT [PomBase:mah] synonym: "swollen spheroid cell during cell quiescence" EXACT [PomBase:mah] synonym: "swollen spheroid cell during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002941 ! swollen spheroid cell created_by: midori creation_date: 2013-12-04T14:15:58Z [Term] id: FYPO:0002943 name: swollen spheroid cell during G0 to G1 transition def: "A cell morphology phenotype in which a cell is shaped in the form of a spheroid, and has a larger volume than normal, when the cell undergoes transition from G0 phase to G1. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] comment: Note that fission yeast cells can enter G0 as a result of either glucose starvation or nitrogen starvation, which can be specified in annotations using conditions. synonym: "enlarged spheroid cell during G0 to G1 transition" RELATED [PomBase:mah] synonym: "enlarged volume spheroid cell during G0 to G1 transition" EXACT [PomBase:mah] synonym: "large spheroid cell during G0 to G1 transition" RELATED [PomBase:vw] synonym: "spheroid cell with increased cell size during G0 to G1 transition" RELATED [PomBase:vw] synonym: "spheroid cell with increased cell volume during G0 to G1 transition" EXACT [PomBase:mah] synonym: "swollen rounded cell during G0 to G1 transition" EXACT [PomBase:mah] synonym: "swollen spheroid cell during cell cycle re-entry" EXACT [PomBase:mah] synonym: "swollen spheroid cell during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "swollen spheroid cell during exit from cell quiescence" EXACT [PomBase:mah] synonym: "swollen spheroid cell during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "swollen spheroid cell during recovery from quiescence" EXACT [PomBase:vw] is_a: FYPO:0002941 ! swollen spheroid cell created_by: midori creation_date: 2013-12-04T14:18:36Z [Term] id: FYPO:0002944 name: decreased RNA level during G0 def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal when the cell is in G0 phase. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during G0" RELATED [PomBase:mah] synonym: "decreased RNA level during cell quiescence" EXACT [PomBase:mah] synonym: "decreased RNA level during quiescence" EXACT [PomBase:mah] synonym: "decreased transcript level during G0" EXACT [PomBase:vw] synonym: "reduced RNA level during G0" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level is_a: FYPO:0003864 ! decreased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:27:54Z [Term] id: FYPO:0002945 name: increased RNA level during G0 def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is in G0 phase is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation during G0" RELATED [PomBase:mah] synonym: "increased RNA level during cell quiescence" EXACT [PomBase:mah] synonym: "increased RNA level during quiescence" EXACT [PomBase:mah] synonym: "increased transcript level during G0" EXACT [PomBase:vw] is_a: FYPO:0001890 ! increased RNA level is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:29:02Z [Term] id: FYPO:0002946 name: abnormal cell wall def: "A physical cellular phenotype in which the cell wall is abnormal." [PomBase:mah] synonym: "cell wall defects" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2013-12-04T14:32:50Z [Term] id: FYPO:0002947 name: abnormal cell wall morphology def: "A physical cellular phenotype in which the size, shape, or structure of the fungal-type cell wall is abnormal." [PomBase:mah] synonym: "cell wall morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0002946 ! abnormal cell wall created_by: midori creation_date: 2013-12-04T14:36:38Z [Term] id: FYPO:0002948 name: delaminated cell wall def: "A physical cellular phenotype in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off." [PomBase:al, PomBase:mah] synonym: "delaminate cell wall" EXACT [PomBase:mah] is_a: FYPO:0002947 ! abnormal cell wall morphology created_by: midori creation_date: 2013-12-04T14:37:13Z [Term] id: FYPO:0002949 name: increased level of substance in cell during G0 def: "A cell phenotype in which the amount a specific substance measured in a cell is higher than normal when the cell is in G0 phase." [PomBase:mah] synonym: "increased accumulation of substance in cell during G0" RELATED [PomBase:mah] synonym: "increased level of substance in cell during cell quiescence" EXACT [PomBase:mah] synonym: "increased level of substance in cell during quiescence" EXACT [PomBase:mah] synonym: "increased substance level during G0" EXACT [PomBase:vw] is_a: FYPO:0000990 ! increased level of substance in cell created_by: midori creation_date: 2013-12-04T14:41:57Z [Term] id: FYPO:0002950 name: increased N-acetyl-D-glucosaminate level during G0 def: "A cell phenotype in which the amount of N-acetyl-D-glucosaminate measured in a cell is higher than normal when the cell is in G0 phase." [PomBase:mah] synonym: "increased N-acetyl-D-glucosaminate accumulation during G0" RELATED [PomBase:mah] synonym: "increased N-acetyl-D-glucosaminate level during cell quiescence" EXACT [PomBase:mah] synonym: "increased N-acetyl-D-glucosaminate level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:44:23Z [Term] id: FYPO:0002951 name: increased L-ergothioneine level during G0 def: "A cell phenotype in which the amount of L-ergothioneine measured in a cell is higher than normal when the cell is in G0 phase." [PomBase:mah] synonym: "increased ergothioneine level during G0" EXACT [CHEBI:4828] synonym: "increased L-ergothioneine accumulation during G0" RELATED [PomBase:mah] synonym: "increased L-ergothioneine level during cell quiescence" EXACT [PomBase:mah] synonym: "increased L-ergothioneine level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:47:32Z [Term] id: FYPO:0002952 name: increased S-methyl-L-ergothioneine level during G0 def: "A cell phenotype in which the amount of S-methyl-L-ergothioneine measured in a cell is higher than normal when the cell is in G0 phase." [PomBase:mah] synonym: "increased S-methyl-L-ergothioneine accumulation during G0" RELATED [PomBase:mah] synonym: "increased S-methyl-L-ergothioneine level during cell quiescence" EXACT [PomBase:mah] synonym: "increased S-methyl-L-ergothioneine level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:48:39Z [Term] id: FYPO:0002953 name: increased S-adenosyl-L-methionine level during G0 def: "A cell phenotype in which the amount of S-adenosyl-L-methionine measured in a cell is higher than normal when the cell is in G0 phase." [PomBase:mah] synonym: "increased S-adenosyl-L-methionine accumulation during G0" RELATED [PomBase:mah] synonym: "increased S-adenosyl-L-methionine level during cell quiescence" EXACT [PomBase:mah] synonym: "increased S-adenosyl-L-methionine level during quiescence" EXACT [PomBase:mah] synonym: "increased S-adenosylmethionine level during G0" EXACT [CHEBI:15414] synonym: "increased SAM level during G0" EXACT [PomBase:mah] is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:51:09Z [Term] id: FYPO:0002954 name: increased S-adenosyl-3-thiopropylamine level during G0 def: "A cell phenotype in which the amount of S-adenosyl-3-thiopropylamine measured in a cell is higher than normal when the cell is in G0 phase." [PomBase:mah] synonym: "increased S-adenosyl-3-thiopropylamine accumulation during G0" RELATED [PomBase:mah] synonym: "increased S-adenosyl-3-thiopropylamine level during cell quiescence" EXACT [PomBase:mah] synonym: "increased S-adenosyl-3-thiopropylamine level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2013-12-04T14:52:31Z [Term] id: FYPO:0002955 name: abnormal G0 to G1 transition def: "A cellular process phenotype in which the transition from G0 phase (quiescence) to G1 is abnormal." [PomBase:mah] synonym: "abnormal exit from cell quiescence" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2013-12-04T14:59:49Z [Term] id: FYPO:0002956 name: abnormal protein localization to nucleus def: "A cell phenotype in which the localization of a protein to the nucleus is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleus and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleus" EXACT [GO:0034504, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2013-12-04T15:47:25Z [Term] id: FYPO:0002957 name: abnormal protein localization to nucleus during meiosis def: "A cell phenotype in which the localization of a protein to the nucleus is abnormal during one or both meiotic nuclear divisions." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleus and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleus during meiosis" EXACT [GO:0034504, PomBase:mah] synonym: "abnormal protein localization to nucleus during meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0002956 ! abnormal protein localization to nucleus created_by: midori creation_date: 2013-12-04T15:48:42Z [Term] id: FYPO:0002958 name: abnormal protein localization to Mei2 nuclear dot def: "A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is abnormal. The Mei2 nuclear dot is a nuclear body that contains Mei2, other proteins, and meiRNA, and forms during meiotic prophase in a fixed position in the horsetail nucleus." [GO:0033620, PomBase:mah] comment: Encompasses both presence of proteins not normally found at the Mei2 nuclear dot and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to Mei2 nuclear dot" EXACT [PomBase:mah] is_a: FYPO:0006183 ! abnormal protein localization to nucleus during meiotic prophase I created_by: midori creation_date: 2013-12-04T15:52:20Z [Term] id: FYPO:0002959 name: decreased RNA level during meiosis def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal during one or both meiotic nuclear divisions. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during meiosis" RELATED [PomBase:mah] synonym: "decreased RNA level during meiotic nuclear division" EXACT [GO:0140013] synonym: "decreased transcript level during meiosis" EXACT [PomBase:vw] synonym: "reduced RNA level during meiosis" EXACT [PomBase:mah] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle created_by: midori creation_date: 2013-12-04T15:55:26Z [Term] id: FYPO:0002960 name: increased level of DSR-containing meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during the meiotic cell cycle, and that contain determinant of selective removal (DSR) sequences, measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth)." [PMID:23980030, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased DSR-containing meiotic gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of DSR-containing meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of DSR-containing meiotic cell cycle gene mRNA during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of DSR-containing meiotic gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of DSR-containing meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of DSR-containing meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of DSR-containing meiotic nuclear division gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002173 ! increased level of meiotic gene mRNA during vegetative growth created_by: midori creation_date: 2013-12-04T15:56:39Z [Term] id: FYPO:0002961 name: delaminated cell wall during G0 def: "A physical cellular phenotype in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off, when the cell is in G0 phase." [PomBase:al, PomBase:mah] synonym: "delaminate cell wall during G0" EXACT [PomBase:mah] synonym: "delaminated cell wall during cell quiescence" EXACT [PomBase:mah] synonym: "delaminated cell wall during G0" RELATED [PomBase:mah] synonym: "delaminated cell wall during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002948 ! delaminated cell wall created_by: midori creation_date: 2013-12-04T14:37:13Z [Term] id: FYPO:0002962 name: abolished protein localization to Mei2 nuclear dot def: "A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is abolished." [PomBase:mah] comment: In some mutants, a focus that contains meiRNA but not Mei2 can form; this is called the meiRNA nuclear dot. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to meiRNA nuclear dot" RELATED [PMID:24920274, PomBase:mah] synonym: "protein localisation to Mei2 nuclear dot abolished" EXACT [PomBase:mah] synonym: "protein localization to Mei2 nuclear dot abolished" EXACT [PomBase:mah] is_a: FYPO:0002958 ! abnormal protein localization to Mei2 nuclear dot created_by: midori creation_date: 2013-12-10T11:56:13Z [Term] id: FYPO:0002963 name: abnormal protein localization to nuclear exosome focus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is abnormal. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1." [PMID:23980030, PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nuclear exosome focus" EXACT [PomBase:mah] synonym: "abnormal protein localization to MMi1 focus" EXACT [PomBase:mah] synonym: "abnormal protein localization to Mmi1 nuclear focus" EXACT [GO:1990251] synonym: "abnormal protein localization to nuclear exosome foci" EXACT [PomBase:mah] synonym: "abnormal protein localization to nuclear exosome focus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nuclear exosome focus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2013-12-10T11:59:35Z [Term] id: FYPO:0002964 name: increased protein localization to nuclear exosome focus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is increased. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1." [PMID:23980030, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nuclear exosome focus" EXACT [PomBase:mah] synonym: "increased protein localization to Mmi1 focus" EXACT [PomBase:mah] synonym: "increased protein localization to Mmi1 nuclear focus" EXACT [GO:1990251] synonym: "increased protein localization to nuclear exosome foci" EXACT [PomBase:mah] synonym: "increased protein localization to nuclear exosome focus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nuclear exosome focus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002963 ! abnormal protein localization to nuclear exosome focus created_by: midori creation_date: 2013-12-10T11:59:52Z [Term] id: FYPO:0002965 name: normal protein localization to nucleolus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleolus" EXACT [PomBase:mah] synonym: "normal protein localization to nucleolus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleolus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-12-10T12:26:53Z [Term] id: FYPO:0002966 name: normal protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004328 ! normal protein localization during mitosis created_by: midori creation_date: 2013-12-10T12:28:10Z [Term] id: FYPO:0002967 name: normal protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001836 ! normal protein localization to spindle pole body created_by: midori creation_date: 2013-12-10T12:30:11Z [Term] id: FYPO:0002968 name: normal protein localization to mitotic spindle pole body during G2 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during G2 phase of the cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle pole body during G2" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic SPB during G2" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole body during G2 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to spindle pole body during G2 vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003308 ! normal protein localization to mitotic spindle pole body during interphase created_by: midori creation_date: 2013-12-10T12:31:29Z [Term] id: FYPO:0002969 name: increased protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "increased protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "increased protein localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body created_by: midori creation_date: 2013-12-10T12:32:39Z [Term] id: FYPO:0002970 name: increased protein localization to mitotic spindle pole body during metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is increased during metaphase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to mitotic spindle pole body during metaphase" EXACT [PomBase:mah] synonym: "increased protein localization to mitotic SPB during metaphase" EXACT [PomBase:mah] synonym: "increased protein localization to mitotic spindle pole body during mitotic metaphase" EXACT [PomBase:mah] synonym: "increased protein localization to spindle pole body during metaphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002969 ! increased protein localization to mitotic spindle pole body created_by: midori creation_date: 2013-12-10T12:33:13Z [Term] id: FYPO:0002971 name: decreased protein localization to mitotic spindle pole body during telophase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during telophase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle pole body during telophase" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic SPB during telophase" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle pole body during mitotic telophase" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during telophase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle pole body during telophase" EXACT [PomBase:mah] is_a: FYPO:0002822 ! decreased protein localization to mitotic spindle pole body during mitosis created_by: midori creation_date: 2013-12-10T12:34:01Z [Term] id: FYPO:0002972 name: increased ubiquitin ligase activity def: "A molecular function phenotype in which the observed rate of ubiquitin ligase activity is increased." [PomBase:mah] synonym: "increased ubiquitin-protein ligase activity" EXACT [GO:0004842] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001912 ! abnormal ubiquitin ligase activity created_by: midori creation_date: 2013-12-10T12:35:59Z [Term] id: FYPO:0002973 name: increased ubiquitin ligase activity during mitotic metaphase def: "A molecular function phenotype in which the observed rate of ubiquitin ligase activity is increased during metaphase of the mitotic cell cycle." [PomBase:mah] synonym: "increased ubiquitin ligase activity during metaphase of mitosis" EXACT [PomBase:mah] synonym: "increased ubiquitin-protein ligase activity during mitotic metaphase" EXACT [GO:0004842] is_a: FYPO:0002972 ! increased ubiquitin ligase activity created_by: midori creation_date: 2013-12-10T12:36:59Z [Term] id: FYPO:0002974 name: normal origin recognition complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which origin recognition complex (ORC) assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal ORC assembly" EXACT [GO:1902561] synonym: "normal origin recognition complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal origin recognition complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2013-12-10T12:42:55Z [Term] id: FYPO:0002975 name: decreased RNA level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydroxyurea is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to hydroxyurea" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2013-12-10T14:52:35Z [Term] id: FYPO:0002976 name: decreased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is decreased during a cellular response to hydroxyurea." [PMID:24006488, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at MCB promoters during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB promoters during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB target genes during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB-containing promoters during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at MCB promoters during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0005314 ! decreased protein localization to chromatin at MCB promoters during vegetative growth created_by: midori creation_date: 2013-12-10T14:55:44Z [Term] id: FYPO:0002977 name: increased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is increased during a cellular response to hydroxyurea." [PMID:24006488, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at MCB promoters during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at MCB promoters during cellular response to HU" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at MCB target genes during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at MCB-containing promoters during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0006740 ! increased protein localization to chromatin at MCB promoters during vegetative growth is_a: FYPO:0007551 ! increased protein localization to chromatin during cellular response to hydroxyurea created_by: midori creation_date: 2013-12-10T14:58:33Z [Term] id: FYPO:0002978 name: increased protein localization to chromatin during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during a cellular response to methyl methanesulfonate." [PMID:24006488, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2013-12-10T15:10:59Z [Term] id: FYPO:0002979 name: normal protein localization to chromatin during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2013-12-10T15:12:28Z [Term] id: FYPO:0002980 name: increased chromatin binding def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] is_a: FYPO:0002576 ! abnormal chromatin binding created_by: midori creation_date: 2013-12-10T15:27:49Z [Term] id: FYPO:0002981 name: increased chromatin binding during cellular response to methyl methanesulfonate def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to methyl methanesulfonate. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "increased chromatin binding during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "increased chromatin binding during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0002980 ! increased chromatin binding created_by: midori creation_date: 2013-12-10T15:28:23Z [Term] id: FYPO:0002982 name: obsolete abolished protein serine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished peptidyl-serine phosphorylation during vegetative growth" EXACT [GO:0018105] synonym: "abolished protein serine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein serine phosphorylation abolished during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002033 created_by: midori creation_date: 2013-12-10T15:30:47Z [Term] id: FYPO:0002983 name: obsolete abolished protein serine phosphorylation during cellular response to DNA damage def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, does not occur during a cellular response to DNA damage." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein serine phosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein serine phosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "protein serine phosphorylation abolished during cellular response to DNA damage" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002898 created_by: midori creation_date: 2013-12-10T15:34:20Z [Term] id: FYPO:0002984 name: normal RNA level during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to methyl methanesulfonate" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to MMS" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2013-12-10T15:37:29Z [Term] id: FYPO:0002985 name: increased RNA level during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to methyl methanesulfonate" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to MMS" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to methyl methanesulfonate" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2013-12-10T15:38:51Z [Term] id: FYPO:0002986 name: increased chromatin binding during cellular response to ionizing radiation def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to ionizing radiation. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "increased chromatin binding during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0002980 ! increased chromatin binding created_by: midori creation_date: 2013-12-10T15:40:22Z [Term] id: FYPO:0002987 name: inviable after spore germination, without cell division, swollen binucleate cell with central constriction alt_id: FYPO:0003288 def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, contains two nuclei, has a larger diameter and volume than normal, and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells." [PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, binucleate without cell division, swollen cell with central constriction" EXACT [PomBase:vw] synonym: "inviable after spore germination, undivided swollen binucleate cell with central constriction" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, swollen binucleate cell with constricted region at cell division site" EXACT [PomBase:vw] synonym: "inviable after spore germination, without cell division, swollen binucleate dumbbell-shaped cell" RELATED [PomBase:mah] synonym: "inviable after spore germination, without cell division, swollen multinucleate cell with central constriction" RELATED [PomBase:mah] synonym: "inviable following spore germination, without cell division, swollen binucleate cell with central constriction" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, swollen binucleate cell with central constriction" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, swollen binucleate cell with central constriction" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape is_a: FYPO:0004257 ! swollen multinucleate vegetative cell created_by: midori creation_date: 2013-12-11T15:47:17Z [Term] id: FYPO:0002988 name: sensitive to ammonium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ammonium. Cells stop growing (and may die) at a concentration of ammonium that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to ammonium" EXACT [PomBase:mah] synonym: "sensitive to ammonium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ammonium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to NH4+" RELATED [CHEBI:28938] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2013-12-11T15:54:16Z [Term] id: FYPO:0002989 name: increased level of transmembrane transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transmembrane transport messenger RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of transmembrane transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of transmembrane transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of transmembrane transport gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased mRNA level of genes involved in transmembrane transport during vegetative growth" EXACT [PomBase:al] synonym: "increased mRNA level of transmembrane transport genes during vegetative growth" EXACT [PomBase:al] synonym: "increased transmembrane transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0004490 ! increased level of transport gene mRNA during vegetative growth created_by: midori creation_date: 2013-12-11T15:57:35Z [Term] id: FYPO:0002990 name: increased leucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased L-leucine import across plasma membrane" EXACT [GO:1903801] synonym: "increased leucine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased leucine import during vegetative growth" EXACT [PomBase:mah] synonym: "increased leucine import into cell" EXACT [PomBase:al] synonym: "increased leucine uptake" EXACT [PomBase:mah] is_a: FYPO:0001139 ! abnormal leucine import created_by: midori creation_date: 2013-12-11T16:01:01Z [Term] id: FYPO:0002991 name: premature mitotic G1/S phase transition during cellular response to hydrogen peroxide def: "A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle begins earlier than normal, during a cellular response to hydrogen peroxide." [PomBase:mah] synonym: "advanced mitotic G1/S phase transition during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "premature cell cycle progression through mitotic G1/S phase transition during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "premature G1/S phase transition during cellular response to hydrogen peroxide during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G1/S phase transition during cellular response to H2O2" EXACT [PomBase:mah] synonym: "premature mitotic G1/S phase transition during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000398 ! premature mitotic G1/S phase transition created_by: midori creation_date: 2013-12-11T16:06:10Z [Term] id: FYPO:0002992 name: premature mitotic G1/S phase transition during cellular response to methyl methanesulfonate def: "A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle begins earlier than normal, during a cellular response to methyl methanesulfonate." [PomBase:mah] synonym: "advanced mitotic G1/S phase transition during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "premature cell cycle progression through mitotic G1/S phase transition during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "premature G1/S phase transition during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G1/S phase transition during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic G1/S phase transition during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "premature mitotic G1/S phase transition during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0000398 ! premature mitotic G1/S phase transition created_by: midori creation_date: 2013-12-11T16:08:23Z [Term] id: FYPO:0002993 name: decreased protein phosphorylation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to methyl methanesulfonate." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to MMS" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-12-11T16:40:16Z [Term] id: FYPO:0002994 name: increased protein localization to chromatin during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during S phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin during mitotic S phase" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during mitotic S phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2013-12-11T16:53:07Z [Term] id: FYPO:0002995 name: normal regulation of DNA replication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of DNA replication is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal regulation of DNA replication during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal regulation of DNA replication during vegetative growth" EXACT [PomBase:mah] synonym: "normal regulation of nuclear cell cycle DNA replication" EXACT [GO:0033262] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2013-12-17T13:57:25Z [Term] id: FYPO:0002996 name: normal negative regulation of DNA replication during cellular response to hydrogen peroxide def: "A regulation phenotype in which regulation of DNA replication during the mitotic cell cycle is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide." [PomBase:mah] synonym: "normal negative regulation of DNA replication during cellular response to H2O2" EXACT [PomBase:mah] synonym: "normal negative regulation of nuclear cell cycle DNA replication during cellular response to hydrogen peroxide" EXACT [GO:1902576] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2013-12-17T14:00:22Z [Term] id: FYPO:0002997 name: normal negative regulation of DNA replication during cellular response to methyl methanesulfonate def: "A regulation phenotype in which regulation of DNA replication during the mitotic cell cycle is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate." [PomBase:mah] synonym: "normal negative regulation of DNA replication during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal negative regulation of DNA replication during cellular response to MMS" EXACT [PomBase:mah] synonym: "normal negative regulation of nuclear cell cycle DNA replication during cellular response to methyl methanesulfonate" EXACT [GO:1902576] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2013-12-17T14:05:50Z [Term] id: FYPO:0002998 name: abolished actomyosin contractile ring assembly, clumped medial cortical nodes def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filaments and associated proteins does not occur, resulting in the failure to form an actomyosin contractile ring, and in which medial cortical nodes form irregular clumps instead of coalescing into the medial cortex ring." [PMID:24127216, PomBase:mah] comment: Note that a ring structure may form without filamentous actin, but a ring lacking F-actin is not considered a contractile ring. synonym: "abolished actomyosin contractile ring assembly, clumped cytokinesis nodes" EXACT [PMID:24127216] synonym: "abolished actomyosin contractile ring assembly, clumped medial cortical nodes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actomyosin contractile ring assembly, clumped medial cortical nodes, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished actomyosin contractile ring formation, clumped medial cortical nodes" RELATED [GO:0000915, PomBase:mah] synonym: "abolished contractile ring assembly, clumped medial cortical nodes" EXACT [PomBase:mah] synonym: "abolished cytokinetic contractile ring assembly, clumped medial cortical nodes" EXACT [PomBase:vw] synonym: "abolished cytokinetic ring assembly, clumped medial cortical nodes" RELATED [PomBase:vw] synonym: "abolished cytokinetic ring formation, clumped medial cortical nodes" RELATED [PomBase:vw] synonym: "abolished mitotic contractile ring assembly, clumped medial cortical nodes" EXACT [PomBase:vw] synonym: "actomyosin contractile ring assembly abolished, clumped medial cortical nodes" EXACT [PomBase:mah] synonym: "cytokinesis defects, contractile ring actin, absent, with clumped medial cortical nodes" RELATED [PomBase:mah] is_a: FYPO:0001009 ! abolished actomyosin contractile ring assembly created_by: midori creation_date: 2013-12-17T14:12:17Z [Term] id: FYPO:0002999 name: normal protein localization to medial cortical node def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "normal protein localization to cortical medial dot" EXACT [PomBase:vw] synonym: "normal protein localization to cytokinetic nodes" RELATED [PMID:24127216] synonym: "normal protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to medial cortical nodes" EXACT [PomBase:mah] synonym: "normal protein recruitment to medial cortical node" RELATED [PomBase:vw] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2013-12-17T14:17:58Z [Term] id: FYPO:0003000 name: abolished actin filament polymerization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filaments from actin monomers does not occur." [PomBase:mah] synonym: "abolished actin filament polymerisation" EXACT [PomBase:mah] synonym: "abolished actin filament polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actin filament polymerization during vegetative growth" EXACT [PomBase:mah] synonym: "actin filament polymerization abolished" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth created_by: midori creation_date: 2013-12-17T14:56:05Z [Term] id: FYPO:0003001 name: actin filaments present in increased numbers def: "A physical cellular phenotype in which cells contain more actin filaments than normal." [PomBase:mah] synonym: "actin filaments present in greater numbers" EXACT [PomBase:mah] synonym: "extra actin filaments" EXACT [PomBase:mah] synonym: "increased level of actin filaments" EXACT [PomBase:al] synonym: "increased number of actin filaments" EXACT [PomBase:al] is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth created_by: midori creation_date: 2013-12-17T15:09:37Z [Term] id: FYPO:0003002 name: decreased protein localization to centromere during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is decreased during metaphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromere during mitotic metaphase" EXACT [PomBase:mah] synonym: "decreased protein localisation to chromosome, centromeric region during mitotic metaphase" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to centromere during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome, centric region during mitotic metaphase" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centromeric region during mitotic metaphase" EXACT [GO:0071459, PomBase:mah] synonym: "reduced protein localization to centromere during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0000450 ! decreased protein localization to centromere during vegetative growth is_a: FYPO:0006175 ! abnormal protein localization to centromere during mitotic metaphase created_by: midori creation_date: 2013-12-17T15:26:00Z [Term] id: FYPO:0003003 name: increased protein localization to kinetochore during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000451 ! increased protein localization to centromere during vegetative growth is_a: FYPO:0001268 ! abnormal protein localization to kinetochore during vegetative growth created_by: midori creation_date: 2013-12-17T15:27:08Z [Term] id: FYPO:0003004 name: increased cellular reactive oxygen species level during vegetative growth def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "increased cellular reactive oxygen species accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular ROS accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased cellular ROS level during vegetative growth" EXACT [PomBase:mah] synonym: "increased ROS accumulation during vegetative growth" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0002142 ! altered cellular reactive oxygen species level created_by: midori creation_date: 2013-12-17T15:47:02Z [Term] id: FYPO:0003005 name: inviable after spore germination, without cell division, with swollen, branched, elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal and forms branches, and does not go on to form a viable dividing cell." [PomBase:mah] synonym: "inviable after spore germination with elongated swollen branched germ tube" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, swollen, branched, elongated cell" EXACT [PomBase:mah] synonym: "inviable following spore germination with swollen, branched, elongated germ tube" EXACT [PomBase:mah] synonym: "inviable germinated spore with swollen, branched, elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with swollen, branched, elongated germ tube" EXACT [PomBase:mah] is_a: FYPO:0002515 ! inviable after spore germination, without cell division, with branched, elongated germ tube is_a: FYPO:0002845 ! inviable swollen elongated septated vegetative cell is_a: FYPO:0002911 ! inviable after spore germination, without cell division, with swollen elongated germ tube is_a: FYPO:0004494 ! inviable branched, swollen, elongated vegetative cell created_by: midori creation_date: 2013-12-17T15:51:27Z [Term] id: FYPO:0003006 name: decreased protein phosphorylation during cellular response to caffeine def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to caffeine." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to caffeine" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2013-12-18T14:51:58Z [Term] id: FYPO:0003007 name: decreased protein level during cellular response to caffeine def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to caffeine is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to caffeine" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to caffeine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to caffeine" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2013-12-18T14:52:59Z [Term] id: FYPO:0003008 name: decreased repression of transcription during cellular response to zinc def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription from RNA polymerase II promoter occurs to a lower extent than normal during a cellular response to zinc. Specific genes are more highly transcribed in the presence of zinc in the mutant than in wild type." [PMID:22496451, PomBase:mah] synonym: "decreased negative regulation of transcription from RNA polymerase II promoter during cellular response to zinc" EXACT [GO:0000122, PomBase:mah] synonym: "decreased repression of transcription during cellular response to zinc during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased repression of transcription during cellular response to zinc during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcriptional repression during cellular response to zinc" EXACT [PomBase:mah] synonym: "reduced repression of transcription during cellular response to zinc" EXACT [PomBase:mah] is_a: FYPO:0000624 ! abnormal negative regulation of transcription during vegetative growth created_by: midori creation_date: 2014-01-03T14:22:41Z [Term] id: FYPO:0003009 name: increased protein localization to centromere outer repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere outer repeat regions of a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromere outer repeat" EXACT [PomBase:mah] synonym: "increased protein localisation to centromeric outer repeat region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromosome, centric outer repeat region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centromeric outer repeat region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to pericentric region" RELATED [PomBase:mah] synonym: "increased protein localization to pericentromeric region" RELATED [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0002840 ! increased protein localization to chromosome during vegetative growth created_by: midori creation_date: 2014-01-03T14:40:14Z [Term] id: FYPO:0003010 name: increased protein localization to subtelomeric heterochromatin during vegetative growth alt_id: FYPO:0004379 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin in subtelomeric regions is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to subtelomeric heterochromatin" EXACT [PomBase:mah] synonym: "increased protein localization to heterochromatin at subtelomere" EXACT [PomBase:mah] synonym: "increased protein localization to subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to telomeric heterochromatin" RELATED [PomBase:mah, PomBase:vw] is_a: FYPO:0001131 ! abnormal protein localization to heterochromatin during vegetative growth is_a: FYPO:0004656 ! increased protein localization to telomere during vegetative growth created_by: midori creation_date: 2014-01-03T15:32:29Z [Term] id: FYPO:0003011 name: increased protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased." [PMID:23936074, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-01-03T15:50:38Z [Term] id: FYPO:0003012 name: mitosis with unreplicated DNA def: "A cellular process phenotype in which cells attempt to undergo mitosis before they have begun to replicate genomic DNA." [PMID:11988741, PomBase:mah] is_a: FYPO:0001046 ! premature mitosis created_by: midori creation_date: 2014-01-08T15:00:35Z [Term] id: FYPO:0003013 name: abnormal actomyosin contractile ring disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring disassembly is abnormal. Contractile ring disassembly is the part of cytokinesis in which the actomyosin contractile ring is disaggregated into its constituent components." [PomBase:mah] synonym: "abnormal actomyosin contractile ring disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring disassembly" EXACT [PomBase:mah] synonym: "abnormal cytokinesis, actomyosin contractile ring disassembly" EXACT [PomBase:mah] synonym: "abnormal cytokinetic contractile ring disassembly" EXACT [PomBase:vw] synonym: "abnormal cytokinetic ring disassembly" RELATED [PomBase:vw] synonym: "abnormal mitotic actomyosin contractile ring disassembly" EXACT [PomBase:mah] synonym: "abnormal mitotic contractile ring disassembly" EXACT [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2014-01-15T10:21:16Z [Term] id: FYPO:0003014 name: decreased rate of actomyosin contractile ring disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring disassembly is decreased. Contractile ring disassembly is the part of cytokinesis in which the actomyosin contractile ring is disaggregated into its constituent components." [PomBase:mah] synonym: "decreased rate of actomyosin contractile ring disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actomyosin contractile ring disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of contractile ring disassembly" EXACT [PomBase:mah] synonym: "decreased rate of cytokinetic contractile ring disassembly" EXACT [PomBase:vw] synonym: "decreased rate of mitotic contractile ring disassembly" EXACT [PomBase:mah] synonym: "reduced rate of actomyosin contractile ring disassembly" EXACT [PomBase:mah] is_a: FYPO:0003013 ! abnormal actomyosin contractile ring disassembly created_by: midori creation_date: 2014-01-15T10:22:22Z [Term] id: FYPO:0003015 name: cell lysis during cellular response to salt stress def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during a cellular response to salt stress. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] synonym: "cell lysis during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell lysis during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "cytolysis during cellular response to salt stress" EXACT [PomBase:mah] synonym: "inviable, lysed cell during cellular response to salt stress" EXACT [PomBase:mah] synonym: "lysed cell in response to salt stress" EXACT [PomBase:al] is_a: FYPO:0000647 ! vegetative cell lysis created_by: midori creation_date: 2014-01-15T10:54:08Z [Term] id: FYPO:0003016 name: cell lysis during cellular response to non-ionic osmotic stress def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during a cellular response to non-ionic osmotic stress. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] synonym: "cell lysis during cellular response to non-ionic osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell lysis during cellular response to non-ionic osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "cytolysis during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] synonym: "inviable, lysed cell during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] synonym: "lysed cell in response to non-ionic osmotic stress" EXACT [PomBase:al] is_a: FYPO:0000647 ! vegetative cell lysis created_by: midori creation_date: 2014-01-15T10:55:13Z [Term] id: FYPO:0003017 name: obsolete inviable elongated vegetative cell during cellular response to salt stress def: "OBSOLETE. A cell morphology phenotype in which a vegetative cell is inviable and elongated during a cellular response to salt stress." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated inviable cell during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell during cellular response to salt stress" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell during cellular response to salt stress" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2014-01-15T10:59:07Z [Term] id: FYPO:0003018 name: obsolete inviable elongated vegetative cell during cellular response to non-ionic osmotic stress def: "OBSOLETE. A cell morphology phenotype in which a vegetative cell is inviable and elongated during a cellular response to non-ionic osmotic stress." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated inviable cell during cellular response to non-ionic osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell during cellular response to non-ionic osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2014-01-15T11:00:24Z [Term] id: FYPO:0003019 name: abnormal protein autophosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, is abnormal. Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [GO:0031952, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein autophosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2014-01-15T11:04:27Z [Term] id: FYPO:0003020 name: abolished protein autophosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, does not occur. Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [GO:0031952, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein autophosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein autophosphorylation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0000775 ! abnormal protein phosphorylation during vegetative growth is_a: FYPO:0002678 ! abolished protein phosphorylation is_a: FYPO:0003019 ! abnormal protein autophosphorylation during vegetative growth created_by: midori creation_date: 2014-01-15T11:05:00Z [Term] id: FYPO:0003021 name: sensitive to EPC def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethyl N-phenylcarbamate (EPC). Cells stop growing (and may die) at a concentration of EPC that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to EPC" EXACT [PomBase:mah] synonym: "sensitive to EPC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to EPC during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ethyl N-phenylcarbamate" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-01-15T11:46:04Z [Term] id: FYPO:0003022 name: resistance to nocodazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nocodazole than normal." [PomBase:mah] synonym: "resistance to nocodazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to nocodazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to nocodazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-01-15T13:47:40Z [Term] id: FYPO:0003023 name: normal growth on EPC def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethyl N-phenylcarbamate (EPC)." [PomBase:mah] synonym: "normal cell population growth in presence of EPC" EXACT [PomBase:mah] synonym: "normal cell population growth on EPC" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on ethyl N-phenylcarbamate" EXACT [PomBase:mah] synonym: "normal cellular response to EPC" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on EPC" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-01-15T13:49:48Z [Term] id: FYPO:0003024 name: abnormal homologous chromosome pairing def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci." [GO:0007129, PomBase:mah] synonym: "abnormal homologous chromosome pairing at meiosis" EXACT [GO:0007129] synonym: "abnormal synapsis" EXACT [GO:0007129] is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle relationship: part_of FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2014-01-15T14:42:37Z [Term] id: FYPO:0003025 name: decreased homologous chromosome pairing def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci." [GO:0007129, PomBase:mah] synonym: "decreased homologous chromosome pairing at meiosis" EXACT [GO:0007129] synonym: "decreased synapsis" EXACT [GO:0007129] synonym: "reduced homologous chromosome pairing" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2014-01-15T14:45:55Z [Term] id: FYPO:0003026 name: delayed onset of homologous chromosome pairing def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) begins later than normal. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci." [GO:0007129, PomBase:mah] synonym: "delayed homologous chromosome pairing" EXACT [PomBase:mah] synonym: "delayed onset of homologous chromosome pairing at meiosis" EXACT [GO:0007129] synonym: "delayed onset of synapsis" EXACT [GO:0007129] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2014-01-15T14:47:13Z [Term] id: FYPO:0003027 name: normal poly(A)+ mRNA export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is normal." [PomBase:mah] synonym: "normal poly(A)+ mRNA export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal poly(A)+ mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-01-15T15:57:46Z [Term] id: FYPO:0003028 name: normal actin cortical patch localization during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal during mitosis." [PomBase:mah] synonym: "normal actin cortical patch localisation during mitosis" EXACT [PomBase:mah] synonym: "normal actin cortical patch localization during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actin cortical patch localization during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal actin cortical patch localization during mitotic M phase" RELATED [PomBase:mah] synonym: "normal actin cortical patch localization during mitotic nuclear division" EXACT [GO:0140014] synonym: "normal actin cortical patch location during mitosis" RELATED [PomBase:mah] synonym: "normal actin patch localization during mitosis" EXACT [PomBase:mah] synonym: "normal F-actin patch localization during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001294 ! normal actin cortical patch localization created_by: midori creation_date: 2014-01-15T16:04:43Z [Term] id: FYPO:0003029 name: decreased mRNA splicing, via spliceosome def: "A cellular process phenotype in which the occurrence of mRNA splicing via the spliceosome is decreased." [PMID:24298023, PomBase:mah] synonym: "decreased mRNA splicing, via spliceosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nuclear mRNA splicing, via spliceosome" EXACT [PomBase:mah] synonym: "decreased splicing" BROAD [PomBase:al] synonym: "reduced mRNA splicing, via spliceosome" EXACT [PomBase:mah] is_a: FYPO:0000189 ! abnormal mRNA splicing, via spliceosome is_a: FYPO:0003040 ! decreased RNA splicing, via splicosome created_by: midori creation_date: 2014-01-17T14:14:59Z [Term] id: FYPO:0003030 name: decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is decreased, where introns have low A/U content and polypyrimidine tracts located approximately 17-19 nt distal to the branch site." [PMID:24298023, PomBase:mah] synonym: "decreased mRNA splicing, via spliceosome, introns with low A/U content and polypyrimidine tracts distal to branch site" EXACT [PomBase:mah] synonym: "decreased nuclear mRNA splicing, via spliceosome, introns with low A/U content and polypyrimidine tracts distal to branch site" EXACT [PomBase:mah] synonym: "decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site" BROAD [PomBase:al] synonym: "decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site during vegetative growth" EXACT [PomBase:mah] synonym: "reduced splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site" EXACT [PomBase:mah] is_a: FYPO:0003242 ! decreased splicing of mRNA introns with low A/U content created_by: midori creation_date: 2014-01-17T14:22:16Z [Term] id: FYPO:0003031 name: mating without nitrogen starvation def: "A cellular process phenotype in which conjugation takes place in cells that are not subject to nitrogen starvation." [PomBase:mah] synonym: "conjugation without nitrogen starvation" EXACT [PomBase:mah] synonym: "mating in the absence of nitrogen starvation" EXACT [PomBase:al] synonym: "mating without nitrogen depletion" EXACT [PomBase:vw] synonym: "mating without nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2014-01-17T14:28:06Z [Term] id: FYPO:0003032 name: decreased RNA level during glucose starvation def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to glucose starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for glucose. Note that cells may enter G0 (quiescence) when subjected to prolonged glucose starvation; this term is not restricted to G0. We recommend noting which RNA(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased RNA accumulation during glucose starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "decreased RNA level during glucose depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during glucose deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during glucose limitation" RELATED [PomBase:mah] synonym: "decreased transcript level during glucose starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2014-01-17T14:30:03Z [Term] id: FYPO:0003033 name: increased RNA level during glucose starvation def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to glucose starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for glucose. We recommend noting which RNA(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "increased RNA accumulation during glucose starvation" RELATED [PomBase:mah] synonym: "increased RNA level during glucose depletion" EXACT [PomBase:vw] synonym: "increased RNA level during glucose deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during glucose limitation" RELATED [PomBase:mah] synonym: "increased transcript level during glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2014-01-17T14:31:39Z [Term] id: FYPO:0003034 name: decreased RNA level during cellular response to UV def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to ultraviolet light is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to ultraviolet light" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to ultraviolet light" EXACT [GO:0034644] synonym: "decreased RNA level during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to UV" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-01-17T14:44:21Z [Term] id: FYPO:0003035 name: normal RNA level during cellular response to UV def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to ultraviolet light is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to UV" NARROW [PomBase:mah] synonym: "normal protein level during cellular response to ultraviolet light" EXACT [GO:0034644] synonym: "normal RNA accumulation during cellular response to UV" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2014-01-17T14:52:09Z [Term] id: FYPO:0003036 name: normal transcription during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to ultraviolet light. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal transcription during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2014-01-17T15:05:39Z [Term] id: FYPO:0003037 name: abnormal cell phenotype def: "A phenotype that shows detectable differences from normal at the level of an individual cell. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal fission yeast cell phenotype" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0001985 ! abnormal phenotype relationship: inheres_in FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2014-01-17T15:10:08Z [Term] id: FYPO:0003038 name: abnormal RNA stability def: "A cell phenotype in which RNA stability is abnormal. RNA molecules may be more or less likely to degrade over a given time period than in wild type. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] synonym: "altered RNA stability" EXACT [PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2014-01-17T15:15:19Z [Term] id: FYPO:0003039 name: decreased RNA stability during cellular response to UV def: "A cell phenotype in which RNA stability is decreased during a cellular response to ultraviolet light. RNA molecules are more likely to degrade over a given time period than in wild type. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:10954610, PomBase:mah] synonym: "decreased RNA stability during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "decreased RNA stability during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA stability during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA stability during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype is_a: FYPO:0003038 ! abnormal RNA stability created_by: midori creation_date: 2014-01-17T15:17:32Z [Term] id: FYPO:0003040 name: decreased RNA splicing, via splicosome def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA splicing is decreased. All RNA splicing may be increased, or splicing of one or more specific RNA molecules may be selectively affected." [PomBase:mah] synonym: "decreased RNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA splicing during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" EXACT [GO:0000377] synonym: "reduced RNA splicing" EXACT [PomBase:mah] is_a: FYPO:0002915 ! abnormal RNA splicing, via spliceosome created_by: midori creation_date: 2014-01-17T15:37:15Z [Term] id: FYPO:0003041 name: decreased snRNA splicing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of small nuclear RNA (snRNA) primary transcripts is decreased." [PomBase:mah] synonym: "decreased snRNA primary transcript RNA splicing" EXACT [PomBase:mah] synonym: "decreased snRNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased snRNA splicing during vegetative growth" EXACT [PomBase:mah] synonym: "increased snRNA splicing, via transesterification reactions with bulged adenosine as nucleophile" EXACT [GO:0000377] synonym: "reduced snRNA splicing" EXACT [PomBase:mah] is_a: FYPO:0003040 ! decreased RNA splicing, via splicosome created_by: midori creation_date: 2014-01-17T15:37:22Z [Term] id: FYPO:0003042 name: abolished protein localization to nuclear exosome focus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci does not occur. Nuclear exosome foci, also called Mmi1 nuclear foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nuclear exosome focus" EXACT [PomBase:mah] synonym: "abolished protein localization to Mmi1 focus" EXACT [PomBase:mah] synonym: "abolished protein localization to Mmi1 nuclear focus" EXACT [GO:1990251] synonym: "abolished protein localization to nuclear exosome focus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nuclear exosome focus during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nuclear exosome focus abolished" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth is_a: FYPO:0002963 ! abnormal protein localization to nuclear exosome focus created_by: midori creation_date: 2014-01-29T15:46:29Z [Term] id: FYPO:0003043 name: increased protein localization to Mei2 nuclear dot def: "A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is increased." [PomBase:mah] comment: In some mutants, a focus that contains meiRNA but not Mei2 can form; this is called the meiRNA nuclear dot. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to Mei2 nuclear dot" EXACT [PomBase:mah] synonym: "increased protein localization to meiRNA nuclear dot" RELATED [PMID:24920274, PomBase:mah] is_a: FYPO:0002958 ! abnormal protein localization to Mei2 nuclear dot created_by: midori creation_date: 2014-01-29T16:11:04Z [Term] id: FYPO:0003044 name: abnormal heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is abnormal. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PomBase:mah] synonym: "abnormal heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal heterochromatin formation" EXACT [GO:0031507, PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2014-01-29T16:26:24Z [Term] id: FYPO:0003045 name: heterochromatin assembly beyond boundary element IRC1R def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the centromere than normal, such that it extends beyond the IRC1R boundary element." [PMID:24013502, PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRC1R during mitotic cell cycle" RELATED [PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRC1R during vegetative growth" EXACT [PomBase:mah] synonym: "heterochromatin formation beyond boundary element IRC1R" EXACT [PomBase:mah] is_a: FYPO:0004948 ! increased spatial extent of centromeric heterochromatin assembly created_by: midori creation_date: 2014-01-29T16:28:55Z [Term] id: FYPO:0003046 name: heterochromatin assembly beyond boundary element IRC3L def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the centromere than normal, such that it extends beyond the IRC3L boundary element." [PMID:24013502, PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRC3L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRC3L during vegetative growth" EXACT [PomBase:mah] synonym: "heterochromatin formation beyond boundary element IRC3L" EXACT [PomBase:mah] is_a: FYPO:0004948 ! increased spatial extent of centromeric heterochromatin assembly created_by: midori creation_date: 2014-01-29T16:36:04Z [Term] id: FYPO:0003047 name: heterochromatin assembly beyond boundary element IRR def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the silent mating-type cassette than normal, such that it extends beyond the IRR boundary element." [PMID:24013502, PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRR during mitotic cell cycle" RELATED [PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRR during vegetative growth" EXACT [PomBase:mah] synonym: "heterochromatin formation beyond boundary element IRR" EXACT [PomBase:mah] is_a: FYPO:0007953 ! increased spatial extent of heterochromatin assembly created_by: midori creation_date: 2014-01-29T16:35:30Z [Term] id: FYPO:0003048 name: abnormal transcript length def: "A phenotype in which a transcript, i.e. an RNA molecule synthesized on a DNA template by RNA polymerase, has an abnormal length." [PMID:22582262, PomBase:mah, SO:0000673] is_a: FYPO:0001985 ! abnormal phenotype relationship: output_of FYPO:0000290 ! transcription phenotype during vegetative growth created_by: midori creation_date: 2014-01-29T17:37:56Z [Term] id: FYPO:0003049 name: increased transcriptional readthrough def: "A phenotype in which a transcript, i.e. an RNA molecule synthesized on a DNA template by RNA polymerase, is longer than normal due to transcription beyond the normal termination site." [PMID:22582262, PomBase:mah, SO:0000673] synonym: "3'-extended transcript" RELATED [PomBase:mah] synonym: "increased transcript length by 3' extension" RELATED [PomBase:mah] synonym: "increased transcript length due to transcriptional readthrough" EXACT [PomBase:mah] synonym: "poly(A) readthrough" RELATED [PomBase:vw] is_a: FYPO:0003048 ! abnormal transcript length relationship: output_of FYPO:0003556 ! abnormal transcription termination created_by: midori creation_date: 2014-01-29T17:38:21Z [Term] id: FYPO:0003050 name: normal homologous chromosome pairing def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type). Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci." [GO:0007129, PomBase:mah] synonym: "normal homologous chromosome pairing at meiosis" EXACT [GO:0007129] synonym: "normal synapsis" EXACT [GO:0007129] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-01-30T14:00:10Z [Term] id: FYPO:0003051 name: normal homologous chromosome pairing at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region such as the omt3 locus on chromosome 1 or the sme2 locus on chromosome 2." [PMID:22582262, PMID:23117617, PMID:24173580, PomBase:mah] synonym: "normal homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "normal synapsis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] is_a: FYPO:0003050 ! normal homologous chromosome pairing created_by: midori creation_date: 2014-01-30T14:03:25Z [Term] id: FYPO:0003052 name: abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal at a cis-acting homologous chromosome pairing region such as the sme2 locus." [PMID:22582262, PMID:23117617, PMID:24173580, PomBase:mah] synonym: "abnormal homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "abnormal homologous chromosome pairing at sme2 locus" NARROW [PomBase:mah] synonym: "abnormal synapsis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] is_a: FYPO:0003024 ! abnormal homologous chromosome pairing created_by: midori creation_date: 2014-01-30T14:33:16Z [Term] id: FYPO:0003053 name: increased homologous chromosome pairing at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is increased (i.e. occurs to a greater extent) at a cis-acting homologous chromosome pairing region such as the sme2 locus." [PMID:22582262, PMID:23117617, PMID:24173580, PomBase:mah] synonym: "increased homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "increased homologous chromosome pairing at sme2 locus" NARROW [PomBase:mah] synonym: "increased synapsis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] is_a: FYPO:0003052 ! abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2014-01-30T14:37:27Z [Term] id: FYPO:0003054 name: decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region such as the omt3 locus on chromosome 1 or the sme2 locus on chromosome 2." [PMID:22582262, PMID:23117617, PMID:24173580, PomBase:mah] synonym: "decreased homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "decreased synapsis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "reduced homologous chromosome pairing at cis-acting homologous chromosome pairing region" EXACT [PomBase:mah] is_a: FYPO:0003025 ! decreased homologous chromosome pairing is_a: FYPO:0003052 ! abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2014-01-30T14:45:24Z [Term] id: FYPO:0003055 name: delayed onset of homologous chromosome pairing at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is delayed at a cis-acting homologous chromosome pairing region such as the sme2 locus." [PMID:22582262, PMID:23117617, PMID:24173580, PomBase:mah] synonym: "delayed homologous chromosome pairing at cis-acting homologous chromosome pairing region" EXACT [PomBase:mah] synonym: "delayed onset of homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "delayed onset of homologous chromosome pairing at sme2 locus" NARROW [PomBase:mah] synonym: "delayed onset of synapsis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] is_a: FYPO:0003026 ! delayed onset of homologous chromosome pairing is_a: FYPO:0003052 ! abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2014-01-30T14:46:10Z [Term] id: FYPO:0003056 name: Mei2 nuclear dot absent from cell def: "A cell phenotype in which the cell does not contain a detectable Mei2 nuclear dot complex." [PomBase:mah] comment: In some mutants, a focus that contains meiRNA but not Mei2 can form; this is called the meiRNA nuclear dot. synonym: "absence of Mei2 dot" EXACT [PomBase:vw] synonym: "absent Mei2 nuclear dot" EXACT [PomBase:mah] synonym: "Mei2 nuclear dot absent from cell during meiotic cell cycle" EXACT [PomBase:mah] synonym: "Mei2 nuclear dot complex absent from cell" EXACT [GO:0033620] synonym: "meiRNA nuclear dot absent from cell" RELATED [PMID:24920274, PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component is_a: FYPO:0007316 ! altered level of macromolecular complex created_by: midori creation_date: 2014-01-30T14:58:38Z [Term] id: FYPO:0003057 name: abnormal RNA localization def: "A cell phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] synonym: "abnormal cellular RNA localisation" EXACT [PomBase:mah] synonym: "abnormal cellular RNA localization" EXACT [PomBase:mah] synonym: "abnormal RNA localisation" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0004853 ! RNA localization phenotype created_by: midori creation_date: 2014-01-30T16:00:06Z [Term] id: FYPO:0003058 name: normal RNA localization def: "A cell phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular RNA localisation" EXACT [PomBase:mah] synonym: "normal cellular RNA localization" EXACT [PomBase:mah] synonym: "normal RNA localisation" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0004853 ! RNA localization phenotype created_by: midori creation_date: 2014-01-30T16:05:30Z [Term] id: FYPO:0003059 name: normal RNA localization to chromatin def: "A cell phenotype in which the localization of an RNA to chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal RNA localisation to chromatin" EXACT [PomBase:mah] is_a: FYPO:0003058 ! normal RNA localization created_by: midori creation_date: 2014-01-30T16:06:28Z [Term] id: FYPO:0003060 name: decreased meiotic recombination at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination at a cis-acting homologous chromosome pairing region such as the sme2 locus is decreased." [PomBase:mah] synonym: "decreased meiotic recombination at sme2 locus" NARROW [PomBase:mah] synonym: "reduced meiotic recombination at cis-acting homologous chromosome pairing region" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2014-01-30T16:09:19Z [Term] id: FYPO:0003061 name: meiotic cell cycle in zygote with unfused nuclei def: "A cellular process phenotype in which the two nuclei in a zygote formed by conjugation with cellular fusion undergo meiosis before karyogamy with nuclear fusion is completed." [PMID:23755176, PomBase:al, PomBase:mah] synonym: "haploid meiosis before karyogamy" EXACT [PomBase:al] synonym: "twin haploid meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0009006 ! abnormal meiotic cell cycle entry created_by: midori creation_date: 2014-01-30T16:35:28Z [Term] id: FYPO:0003062 name: abnormal nuclear congression during mating def: "A cellular process phenotype in which nuclear migration involved in conjugation with cellular fusion is abnormal." [PomBase:mah] synonym: "abnormal nuclear congression during karyogamy" RELATED [PomBase:al] synonym: "abnormal nuclear migration during mating" EXACT [] synonym: "abnormal nuclear migration involved in conjugation with cellular fusion" EXACT [GO:0000743] synonym: "abnormal nuclear movement during mating" EXACT [PomBase:mah] synonym: "abnormal nuclear movement during shmooing" RELATED [PomBase:vw] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2014-01-30T16:43:32Z [Term] id: FYPO:0003063 name: abnormal cytoskeleton morphology def: "A physical cellular phenotype in which the size, shape, or structure of the cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in abnormal cytoskeleton morphology. is_a: FYPO:0002397 ! abnormal cytoskeleton created_by: midori creation_date: 2014-01-30T16:47:41Z [Term] id: FYPO:0003064 name: abnormal microtubule cytoskeleton morphology def: "A physical cellular phenotype in which the size, shape, or structure of the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. is_a: FYPO:0002399 ! abnormal microtubule cytoskeleton is_a: FYPO:0003063 ! abnormal cytoskeleton morphology created_by: midori creation_date: 2014-01-30T16:47:52Z [Term] id: FYPO:0003065 name: abnormal microtubule cytoskeleton morphology during mating def: "A physical cellular phenotype in which the size, shape, or structure of the microtubule cytoskeleton is abnormal during conjugation with cellular fusion." [PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. synonym: "abnormal microtubule cytoskeleton morphology during conjugation with cellular fusion" EXACT [GO:0000747] synonym: "abnormal microtubule cytoskeleton morphology during karyogamy" RELATED [PomBase:al] is_a: FYPO:0003064 ! abnormal microtubule cytoskeleton morphology created_by: midori creation_date: 2014-01-30T16:52:27Z [Term] id: FYPO:0003066 name: abnormal sporulation resulting in formation of ascus with fewer than four spores def: "A sporulation phenotype in which asci that contain one, two, or three spores form following conjugation and subsequent sporulation." [PomBase:al, PomBase:mah] synonym: "abnormal ascospore formation resulting in formation of asci with fewer than four spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of asci with fewer than four spores" EXACT [PomBase:mah] is_a: FYPO:0001894 ! abnormal sporulation resulting in formation of ascus with more or fewer than four spores created_by: midori creation_date: 2014-01-30T17:00:30Z [Term] id: FYPO:0003067 name: abnormal replication fork reversal def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which stalled replication forks are unwound four-stranded structures resembling Holliday junctions, but are not subsequently resolved correctly." [PomBase:mah] synonym: "abnormal replication fork reversal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal replication fork reversal during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-02-04T15:09:57Z [Term] id: FYPO:0003068 name: decreased protein localization to chromatin at replication forks during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication forks is decreased during a cellular response to hydroxyurea." [PMID:22682245, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at replication forks during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at replication forks during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at replication forks during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at replication forks during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at replication forks during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-02-04T15:48:16Z [Term] id: FYPO:0003069 name: normal protein localization to chromatin at replication forks during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication forks is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea." [PMID:22682245, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at replication forks during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at nuclear replication forks during cellular response to hydroxyurea" EXACT [GO:0043596] synonym: "normal protein localization to chromatin at replication forks during cellular response to HU" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at replication forks during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at replication forks during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-02-04T16:02:45Z [Term] id: FYPO:0003070 name: abnormal single-stranded DNA 5'-3' exodeoxyribonuclease activity def: "A molecular function phenotype in which the observed rate of a single-stranded DNA 5'-3' exodeoxyribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-02-04T16:06:17Z [Term] id: FYPO:0003071 name: abolished single-stranded DNA 5'-3' exodeoxyribonuclease activity def: "A molecular function phenotype in which a single-stranded DNA 5'-3' exodeoxyribonuclease activity is absent." [PomBase:mah] synonym: "single-stranded DNA 5'-3' exodeoxyribonuclease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003070 ! abnormal single-stranded DNA 5'-3' exodeoxyribonuclease activity created_by: midori creation_date: 2014-02-04T16:06:25Z [Term] id: FYPO:0003072 name: abnormal primary amine oxidase activity def: "A molecular function phenotype in which the observed rate of primary amine oxidase activity is abnormal." [PomBase:mah] synonym: "decreased copper amine oxidase activity" NARROW [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-02-06T11:28:56Z [Term] id: FYPO:0003073 name: decreased primary amine oxidase activity def: "A molecular function phenotype in which the observed rate of primary amine oxidase activity is decreased." [PomBase:mah] synonym: "decreased copper amine oxidase activity" NARROW [PomBase:mah] synonym: "reduced primary amine oxidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003072 ! abnormal primary amine oxidase activity created_by: midori creation_date: 2014-02-06T11:29:12Z [Term] id: FYPO:0003074 name: abolished protein localization to pericentric heterochromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to pericentric heterochromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to centromeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localisation to pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to centric heterochromatin during vegetative growth" EXACT [GO:0005721] synonym: "abolished protein localization to centromeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nuclear centromeric heterochromatin" EXACT [PomBase:mah] synonym: "abolished protein localization to pericentric heterochromatin during mitotic cell cycle during mitotic cell cycle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to centromeric heterochromatin abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to pericentric heterochromatin abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2014-02-06T11:51:20Z [Term] id: FYPO:0003075 name: normal protein kinase activity def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-02-06T11:56:28Z [Term] id: FYPO:0003076 name: normal protein autophosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [GO:0031952, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein autophosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2014-02-06T12:00:05Z [Term] id: FYPO:0003077 name: increased protein autophosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophosphorylation of one or more specific proteins, or of specific protein sites, is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein autophosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003019 ! abnormal protein autophosphorylation during vegetative growth created_by: midori creation_date: 2014-02-06T14:05:27Z [Term] id: FYPO:0003078 name: abolished protein autophosphorylation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to DNA damage. Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [GO:0031952, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein autophosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein autophosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "protein autophosphorylation abolished during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003020 ! abolished protein autophosphorylation during vegetative growth created_by: midori creation_date: 2014-02-06T14:07:01Z [Term] id: FYPO:0003079 name: abnormal genetic imprinting at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus is abnormal." [PomBase:mah] synonym: "abnormal genetic imprinting at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal genetic imprinting at mating-type locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-02-06T14:35:53Z [Term] id: FYPO:0003080 name: abolished genetic imprinting at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus does not occur." [PomBase:mah] synonym: "abolished genetic imprinting at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "genetic imprinting at mating-type locus abolished" EXACT [PomBase:mah] synonym: "genetic imprinting at mating-type locus abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003079 ! abnormal genetic imprinting at mating-type locus created_by: midori creation_date: 2014-02-06T14:36:37Z [Term] id: FYPO:0003081 name: decreased genetic imprinting at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased genetic imprinting at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased genetic imprinting at mating-type locus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced genetic imprinting at mating-type locus" EXACT [PomBase:mah] is_a: FYPO:0003079 ! abnormal genetic imprinting at mating-type locus created_by: midori creation_date: 2014-02-06T14:36:46Z [Term] id: FYPO:0003082 name: normal genetic imprinting at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal genetic imprinting at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal genetic imprinting at mating-type locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-02-06T14:53:36Z [Term] id: FYPO:0003083 name: abnormal replication fork arrest at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus is abnormal." [PomBase:mah] synonym: "abnormal replication fork arrest at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal replication fork arrest at mating-type locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-02-06T15:11:09Z [Term] id: FYPO:0003084 name: abolished replication fork arrest at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus does not occur." [PomBase:mah] synonym: "abolished replication fork arrest at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "replication fork arrest at mating-type locus abolished" EXACT [PomBase:mah] synonym: "replication fork arrest at mating-type locus abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003083 ! abnormal replication fork arrest at mating-type locus created_by: midori creation_date: 2014-02-06T15:11:27Z [Term] id: FYPO:0003085 name: decreased replication fork arrest at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased replication fork arrest at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork arrest at mating-type locus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced replication fork arrest at mating-type locus" EXACT [PomBase:mah] is_a: FYPO:0003083 ! abnormal replication fork arrest at mating-type locus created_by: midori creation_date: 2014-02-06T15:11:41Z [Term] id: FYPO:0003086 name: normal chromatin binding def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-02-06T15:16:11Z [Term] id: FYPO:0003087 name: normal chromatin binding at mating-type region replication fork barrier def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at a replication fork barrier in the mating-type region." [PomBase:mah] is_a: FYPO:0003086 ! normal chromatin binding created_by: midori creation_date: 2014-02-06T15:16:52Z [Term] id: FYPO:0003088 name: abnormal replication fork arrest def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest is abnormal." [PomBase:mah] synonym: "abnormal replication fork arrest during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal replication fork arrest during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-02-06T15:39:06Z [Term] id: FYPO:0003089 name: abnormal replication fork arrest at rDNA repeats def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at sites within the eukaryotic rDNA repeat spacer is abnormal." [PomBase:mah] synonym: "abnormal replication fork arrest at rDNA repeats during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal replication fork arrest at rDNA repeats during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal replication fork arrest at ribosomal DNA repeats" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-02-06T15:39:57Z [Term] id: FYPO:0003090 name: decreased replication fork arrest at rDNA repeats def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic rDNA repeat spacer occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased replication fork arrest at rDNA repeats during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork arrest at rDNA repeats during vegetative growth" EXACT [PomBase:mah] synonym: "decreased replication fork arrest at ribosomal DNA repeats" EXACT [PomBase:mah] synonym: "reduced replication fork arrest at rDNA repeats" EXACT [PomBase:mah] is_a: FYPO:0003089 ! abnormal replication fork arrest at rDNA repeats created_by: midori creation_date: 2014-02-06T15:41:07Z [Term] id: FYPO:0003091 name: decreased chromatin binding at rDNA replication fork barrier def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at a replication fork pausing site within the eukaryotic rDNA repeat spacer in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "decreased chromatin binding at ribosomal DNA replication fork barrier" EXACT [PomBase:mah] synonym: "reduced chromatin binding at rDNA replication fork barrier" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2014-02-06T15:46:03Z [Term] id: FYPO:0003092 name: decreased chromatin binding at mating-type region replication fork barrier def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at a replication fork pausing site within the mating-type region in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "reduced chromatin binding at mating-type region replication fork barrier" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2014-02-06T15:48:12Z [Term] id: FYPO:0003093 name: increased Argonaute-associated RNA length def: "A phenotype in which small RNA molecules physically associated with the Argonaute protein (Ago1) are longer than normal." [PMID:24095277, PomBase:mah] synonym: "increased Argonaute-associated priRNA length" NARROW [PomBase:mah] synonym: "increased Argonaute-associated siRNA length" NARROW [PomBase:mah] synonym: "increased length of Ago1-associated RNA" NARROW [PomBase:mah] synonym: "increased length of Argonaute-associated RNA" EXACT [PomBase:mah] synonym: "increased length of Argonaute-associated small RNA" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-02-13T15:11:35Z [Term] id: FYPO:0003094 name: decreased centromeric outer repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are present at lower levels than normal." [PMID:24095277, PomBase:mah] comment: This term encompasses both unprocessed RNA transcribed from the centromere outer repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'abnormal chromatin silencing at centromere outer repeat region' (FYPO:0002346). synonym: "decreased accumulation of centromeric outer repeat transcripts" RELATED [PomBase:mah] synonym: "decreased accumulation of centromeric outer repeat transcripts during vegetative growth" RELATED [PomBase:mah] synonym: "decreased accumulation of non-coding outer repeat transcripts" EXACT [PomBase:vw] synonym: "decreased centromere outer repeat transcript level" EXACT [PomBase:mah] synonym: "decreased centromeric outer repeat transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased centromeric outer repeat transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased centromeric outer repeat-derived transcript level" EXACT [PomBase:vw] synonym: "decreased level of centromeric outer repeat transcripts" EXACT [PomBase:mah] synonym: "reduced centromeric outer repeat transcript level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-02-13T15:22:03Z [Term] id: FYPO:0003095 name: viable elongated vegetative cell, with progressive elongation def: "A cell morphology phenotype in which a vegetative cell is viable and elongated, and continues to become longer over successive generations. The cell also undergoes mitosis beginning when the cell is longer than normal." [PMID:24013504, PomBase:mah] comment: Note that progressive cell elongation usually results from DNA damage checkpoint activation. Consider also annotating to 'normal DNA damage checkpoint' (FYPO:0001705) or 'increased DNA damage checkpoint activation' (FYPO:0001707). synonym: "progressively elongating viable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0003481 ! viable elongated vegetative cell, elongated upon mitotic entry created_by: midori creation_date: 2014-02-19T10:34:57Z [Term] id: FYPO:0003096 name: decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 methylation at centromere outer repeat during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 methylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 methylation at centromeric dg repeats during vegetative growth" NARROW [PMID:24095277, PomBase:mah] synonym: "decreased histone H3-K9 methylation at centromeric outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 methylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 methylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased histone H3K9me at centromere outer repeat during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation at centromere outer repeat during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth is_a: FYPO:0007374 ! abnormal histone methylation at centromere during vegetative growth created_by: midori creation_date: 2014-02-13T15:55:37Z [Term] id: FYPO:0003097 name: abolished histone H3-K9 methylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in centromere outer repeat regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 methylation at centromere outer repeat during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished histone H3-K9 methylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 methylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 methylation at centromeric dg repeats during vegetative growth" NARROW [PMID:24095277, PomBase:mah] synonym: "abolished histone H3-K9 methylation at centromeric outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 methylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 methylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone H3K9me at centromere outer repeat during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "abolished histone lysine H3 K9 methylation at centromere outer repeat during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "histone H3-K9 methylation at centromere outer repeat abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002566 ! abolished histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-02-13T15:57:50Z [Term] id: FYPO:0003098 name: abnormal heterochromatin assembly at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is abnormal in centromere outer repeat regions. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PomBase:mah] synonym: "abnormal heterochromatin assembly at centromere outer repeat at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal heterochromatin assembly at centromere outer repeat at centromeric outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal heterochromatin assembly at centromere outer repeat at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal heterochromatin assembly at centromere outer repeat at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal heterochromatin assembly at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal heterochromatin formation at centromere outer repeat during vegetative growth" EXACT [GO:0031507, PomBase:mah] is_a: FYPO:0003044 ! abnormal heterochromatin assembly created_by: midori creation_date: 2014-02-13T16:00:00Z [Term] id: FYPO:0003099 name: normal heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is normal (i.e. indistinguishable from wild type). Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PomBase:mah] synonym: "normal heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal heterochromatin formation" EXACT [GO:0031507, PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2014-02-13T16:01:35Z [Term] id: FYPO:0003100 name: normal heterochromatin assembly at protein coding gene def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is normal (i.e. indistinguishable from wild type) in regions containing protein-coding genes. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PMID:24095277, PomBase:mah] synonym: "normal heterochromatin assembly at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal heterochromatin assembly at protein coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "normal heterochromatin assembly at protein-coding gene" EXACT [PomBase:mah] synonym: "normal heterochromatin formation at protein coding gene" EXACT [GO:0031507, PomBase:mah] is_a: FYPO:0003099 ! normal heterochromatin assembly created_by: midori creation_date: 2014-02-13T16:02:53Z [Term] id: FYPO:0003101 name: decreased heterochromatin assembly at protein coding gene def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly occurs to a lower extent than normal in regions containing protein-coding genes. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PMID:24095277, PomBase:mah] synonym: "decreased heterochromatin assembly at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased heterochromatin assembly at protein coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased heterochromatin assembly at protein-coding gene" EXACT [PomBase:mah] synonym: "decreased heterochromatin formation at protein coding gene" EXACT [GO:0031507, PomBase:mah] synonym: "reduced heterochromatin assembly at protein coding gene" EXACT [PomBase:mah] is_a: FYPO:0004543 ! abnormal heterochromatin organization during vegetative growth is_a: FYPO:0006356 ! abnormal chromatin remodeling created_by: midori creation_date: 2014-02-13T16:17:23Z [Term] id: FYPO:0003102 name: increased histone H3-K9 methylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation at protein coding gene during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 methylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me at protein coding gene during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at protein coding gene during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-02-13T16:19:52Z [Term] id: FYPO:0003103 name: decreased mRNA-derived small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from mRNA transcripts measured in a cell is lower than normal." [PMID:24095277, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased accumulation of mRNA-derived small RNAs" RELATED [PomBase:vw] synonym: "decreased mRNA-derived small RNA accumulation" RELATED [PomBase:mah] synonym: "decreased mRNA-derived small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mRNA-derived small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mRNA-derived small transcript level" EXACT [PomBase:mah] synonym: "decreased protein-coding gene-derived small RNA level" RELATED [PomBase:mah] synonym: "reduced mRNA-derived small RNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-02-13T16:36:11Z [Term] id: FYPO:0003104 name: increased mRNA-derived small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from mRNA transcripts measured in a cell is greater than normal." [PMID:24095277, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased accumulation of mRNA-derived small RNAs" RELATED [PomBase:vw] synonym: "increased mRNA-derived small RNA accumulation" RELATED [PomBase:mah] synonym: "increased mRNA-derived small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mRNA-derived small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mRNA-derived small transcript level" EXACT [PomBase:mah] synonym: "increased protein-coding gene-derived small RNA level" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2014-02-13T16:38:10Z [Term] id: FYPO:0003105 name: increased transposable element-derived small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell is greater than normal." [PMID:24095277, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased accumulation of transposable element-derived small RNAs" RELATED [PomBase:vw] synonym: "increased transposable element-derived small RNA accumulation" RELATED [PomBase:mah] synonym: "increased transposable element-derived small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transposable element-derived small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased transposable element-derived small transcript level" EXACT [PomBase:mah] synonym: "increased transposon-derived small RNA level" EXACT [PomBase:mah] is_a: FYPO:0003558 ! increased repeat element RNA level created_by: midori creation_date: 2014-02-13T16:42:33Z [Term] id: FYPO:0003106 name: stable shortened telomeres during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are shorter than normal, and that remain at a consistent length over successive generations." [PMID:24013504, PomBase:mah] synonym: "stable decreased telomere length during vegetative growth" EXACT [PomBase:mah] synonym: "stable shortened telomeres during mitotic cell cycle" RELATED [PomBase:mah] synonym: "stably shortened telomeres during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002239 ! shortened telomeres during vegetative growth created_by: midori creation_date: 2014-02-19T11:03:54Z [Term] id: FYPO:0003107 name: progressively shortening telomeres during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are shorter than normal, and that continue to decrease in length over successive generations." [PMID:24013504, PomBase:mah] synonym: "progressively decreasing telomere length during vegetative growth" EXACT [PomBase:mah] synonym: "progressively shortening telomeres during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002239 ! shortened telomeres during vegetative growth created_by: midori creation_date: 2014-02-19T11:05:13Z [Term] id: FYPO:0003108 name: abnormal protein localization to telomere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the telomere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "abnormal protein localisation to telomere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "abnormal protein localization to telomere during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004888 ! abnormal protein localization to telomere created_by: midori creation_date: 2014-02-19T11:07:53Z [Term] id: FYPO:0003109 name: abolished protein localization to telomere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "abolished protein localisation to telomere during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "abolished protein localization to telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from telomere during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to telomere abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003108 ! abnormal protein localization to telomere during vegetative growth created_by: midori creation_date: 2014-02-19T11:08:34Z [Term] id: FYPO:0003110 name: sensitive to caffeine and rapamycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of caffeine and rapamycin. Cells stop growing (and may die) at concentrations of caffeine and rapamycin that allow wild type cells to grow." [PMID:23551936, PomBase:mah] synonym: "hypersensitive to caffeine and rapamycin" EXACT [PomBase:mah] synonym: "sensitive to caffeine and rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to caffeine and rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to caffeine and rapamycin in combination" EXACT [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-02-19T11:21:00Z [Term] id: FYPO:0003111 name: abnormal ubiquitinyl hydrolase activity def: "A molecular function phenotype in which the observed rate of ubiquitinyl hydrolase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-02-19T11:36:19Z [Term] id: FYPO:0003112 name: increased ubiquitinyl hydrolase activity def: "A molecular function phenotype in which the observed rate of ubiquitinyl hydrolase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003111 ! abnormal ubiquitinyl hydrolase activity created_by: midori creation_date: 2014-02-19T11:36:28Z [Term] id: FYPO:0003113 name: resistance to sodium nitroprusside def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium nitroprusside than normal." [PomBase:mah] synonym: "resistance to sodium nitroprusside during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to sodium nitroprusside during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to sodium nitroprusside" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-02-19T11:38:18Z [Term] id: FYPO:0003114 name: increased cellular nitric oxide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular nitric oxide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular NO level during vegetative growth" EXACT [CHEBI:16480] synonym: "increased nitric oxide accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0003004 ! increased cellular reactive oxygen species level during vegetative growth is_a: FYPO:0006408 ! altered cellular nitric oxide level created_by: midori creation_date: 2014-02-19T11:43:42Z [Term] id: FYPO:0003115 name: resistance to L-methionine (R)-S-oxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-methionine (R)-S-oxide than normal." [PomBase:mah] synonym: "resistance to L-methionine (R)-S-oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to L-methionine (R)-S-oxide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to L-methionine (R)-S-oxide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-02-19T11:45:51Z [Term] id: FYPO:0003116 name: sensitive to plumbagin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to plumbagin. Cells stop growing (and may die) at a concentration of plumbagin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to plumbagin" EXACT [PomBase:mah] synonym: "sensitive to plumbagin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to plumbagin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-02-19T14:29:40Z [Term] id: FYPO:0003117 name: increased cellular reactive oxygen species level during cellular response to plumbagin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal during a cellular response to plumbagin." [PomBase:mah] synonym: "increased cellular reactive oxygen species accumulation during cellular response to plumbagin" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to plumbagin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to plumbagin during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular ROS accumulation during cellular response to plumbagin" RELATED [PomBase:mah] synonym: "increased cellular ROS level during cellular response to plumbagin" EXACT [PomBase:mah] synonym: "increased ROS accumulation during cellular response to plumbagin" RELATED [PomBase:al] is_a: FYPO:0003004 ! increased cellular reactive oxygen species level during vegetative growth created_by: midori creation_date: 2014-02-19T14:31:55Z [Term] id: FYPO:0003118 name: normal cellular reactive oxygen species level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular reactive oxygen species level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular ROS level" EXACT [PomBase:mah] synonym: "normal level of reactive oxygen species in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2014-02-19T14:36:02Z [Term] id: FYPO:0003119 name: increased nuclear polyadenylated mRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated messenger RNA (mRNA) measured in the nucleus is higher than normal. Total mRNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased nuclear poly(A)+ mRNA level during vegetative growth" EXACT [PomBase:vw] synonym: "increased nuclear polyadenylated messenger RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased nuclear polyadenylated mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased nuclear polyadenylated mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nuclear polyadenylated mRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "nuclear poly(A)+ mRNA accumulation" RELATED [PomBase:vw] synonym: "nuclear poly-A mRNA accumulation" RELATED [PomBase:vw] is_a: FYPO:0000911 ! increased nuclear RNA level during vegetative growth created_by: midori creation_date: 2014-02-19T15:21:49Z [Term] id: FYPO:0003120 name: decreased transcription during glucose starvation def: "A cellular process phenotype in which transcription occurs to a lower extent than normal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased transcription during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "decreased transcription during glucose depletion" EXACT [PomBase:vw] synonym: "decreased transcription during glucose deprivation" EXACT [PomBase:vw] synonym: "decreased transcription during glucose limitation" RELATED [PomBase:mah] synonym: "decreased transcription in response to glucose starvation" EXACT [PomBase:mah, PomBase:vw] synonym: "reduced transcription during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0002876 ! decreased transcription is_a: FYPO:0006354 ! abnormal transcription during glucose starvation created_by: midori creation_date: 2014-02-19T15:29:30Z [Term] id: FYPO:0003121 name: normal rate of homologous chromosome pairing at cis-acting homologous chromosome pairing region def: "A cellular process phenotype in which the rate, or speed, of homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region such as the sme2 locus." [PMID:22582262, PMID:23117617, PMID:24173580, PomBase:mah] synonym: "normal rate of homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] synonym: "normal rate of homologous chromosome pairing at sme2 locus" NARROW [PomBase:mah] synonym: "normal rate of synapsis at cis-acting homologous chromosome pairing region" EXACT [GO:0007129] is_a: FYPO:0003051 ! normal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2014-02-19T15:39:51Z [Term] id: FYPO:0003122 name: decreased protein autophosphorylation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophosphorylation of one or more specific proteins, or of specific protein sites, is decreased during a cellular response to DNA damage." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein autophosphorylation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein autophosphorylation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein autophosphorylation during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0003298 ! decreased protein autophosphorylation during vegetative growth created_by: midori creation_date: 2014-02-19T15:58:59Z [Term] id: FYPO:0003123 name: abolished protein localization to nuclear periphery during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is abolished during a cellular response to heat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nuclear periphery during cellular response to heat" EXACT [PomBase:mah] synonym: "abolished protein localization to nuclear periphery during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nuclear periphery during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nuclear periphery abolished during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0002568 ! abolished protein localization to nuclear periphery created_by: midori creation_date: 2014-02-19T16:07:20Z [Term] id: FYPO:0003124 name: abnormal cytoplasmic translation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translation in the cytoplasm is abnormal. Translation is the synthesis of a protein using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain." [GO:0002183, PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'altered protein level' (FYPO:0000834) or one of its descendants. synonym: "abnormal cytoplasmic protein biosynthesis" EXACT [GO:0006412, PomBase:mah] synonym: "abnormal cytoplasmic protein synthesis" EXACT [GO:0006412, PomBase:mah] synonym: "abnormal cytoplasmic translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cytoplasmic translation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001797 ! abnormal translation created_by: midori creation_date: 2014-02-19T16:10:41Z [Term] id: FYPO:0003125 name: decreased cytoplasmic translational initiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translational initiation in the cytoplasm is decreased." [PomBase:mah] comment: Note that this term should be used only when an experiment measures the initiation of protein synthesis directly, e.g. by ribosome profiling. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "decreased cytoplasmic translation initiation" EXACT [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cytoplasmic translational initiation" EXACT [PomBase:mah] is_a: FYPO:0001798 ! decreased translation is_a: FYPO:0003124 ! abnormal cytoplasmic translation created_by: midori creation_date: 2014-02-19T16:10:56Z [Term] id: FYPO:0003126 name: post-anaphase array absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable post-anaphase array of microtubules." [PMID:24006493, PMID:9601091, PomBase:mah] synonym: "absent post-anaphase array" EXACT [PomBase:mah] synonym: "PAA absent from cell" EXACT [PMID:9601091] synonym: "post-anaphase array absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "post-anaphase array absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "post-anaphase microtubule array absent from cell" EXACT [PomBase:mah] is_a: FYPO:0004316 ! abnormal post-anaphase array created_by: midori creation_date: 2014-02-19T16:39:51Z [Term] id: FYPO:0003127 name: decreased cellular nitric oxide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular nitric oxide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular NO level during vegetative growth" EXACT [CHEBI:16480] synonym: "decreased nitric oxide accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced cellular nitric oxide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002780 ! decreased cellular reactive oxygen species level during vegetative growth is_a: FYPO:0006408 ! altered cellular nitric oxide level created_by: midori creation_date: 2014-02-20T14:02:44Z [Term] id: FYPO:0003128 name: inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase def: "A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested in M phase." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest in M phase during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell arrested in M" EXACT [PomBase:jh] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in M phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitosis" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest in M phase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic M phase arrest" EXACT [PomBase:vw] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic nuclear division arrest" EXACT [PomBase:vw] synonym: "lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in M-phase with elongated inviable mononucleate aseptate cell" EXACT [PomBase:vw] synonym: "mitotic M-phase arrested elongated inviable mononucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "nuclear division arrest without septation (elongated cell)" EXACT [PomBase:vw] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase is_a: FYPO:0000839 ! inviable elongated mononucleate aseptate cell relationship: has_part FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2014-02-20T14:09:34Z [Term] id: FYPO:0003129 name: loss of punctate nuclear protein localization during cellular response to ionizing radiation def: "A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished punctate nuclear protein localization during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localisation during cellular response to ionising radiation" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localization during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "loss of punctate nuclear protein localization during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localization during cellular response to IR" EXACT [PomBase:al] is_a: FYPO:0003483 ! decreased punctate nuclear protein localization during cellular response to ionizing radiation is_a: FYPO:0005863 ! loss of punctate nuclear protein localization created_by: midori creation_date: 2014-02-20T14:20:27Z [Term] id: FYPO:0003130 name: premature mitotic G1 phase entry during cellular response to ionizing radiation def: "A cellular process phenotype in which entry into the G1 phase of the mitotic cell cycle (exit from mitosis) begins earlier than normal during a cellular response to ionizing radiation." [PomBase:mah] synonym: "accelerated entry into G1 during cellular response to ionizing radiation" RELATED [PomBase:al] synonym: "advanced mitotic G1 phase entry during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "mitotic cell cycle advance in G1 during cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "premature exit from mitosis during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "premature G1 phase entry during cellular response to ionizing radiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G1 phase entry during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic G1 phase entry during cellular response to IR" EXACT [PomBase:al] synonym: "premature mitotic G1 progression during cellular response to ionizing radiation" RELATED [PomBase:mah] is_a: FYPO:0000828 ! premature mitotic G1 phase entry created_by: midori creation_date: 2014-02-20T14:24:36Z [Term] id: FYPO:0003131 name: normal protein phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to IR" EXACT [PomBase:al] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-02-20T14:27:11Z [Term] id: FYPO:0003132 name: normal punctate nuclear localization during cellular response to ionizing radiation def: "A cell phenotype in which a gene product is normally localized to discrete regions in the nucleus (i.e. its localization is indistinguishable from wild type), visible as foci or dots by microscopy, during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal punctate nuclear localisation during cellular response to ionising radiation" RELATED [PomBase:mah] synonym: "normal punctate nuclear localization during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal punctate nuclear localization during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal punctate nuclear localization during cellular response to IR" EXACT [PomBase:al] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2014-02-20T14:29:03Z [Term] id: FYPO:0003133 name: galactomannan absent from cell wall def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is too low to detect." [PomBase:mah] synonym: "galactomannan absent from cell surface" RELATED [PomBase:al] synonym: "galactomannan absent from cell wall during mitotic cell cycle" RELATED [PomBase:mah] synonym: "galactomannan absent from cell wall during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001209 ! polysaccharide absent from cell is_a: FYPO:0002265 ! decreased cell wall galactomannan level is_a: FYPO:0002628 ! decreased level of substance in cell wall during vegetative growth created_by: midori creation_date: 2014-02-20T14:45:12Z [Term] id: FYPO:0003134 name: increased cell wall alpha-glucan level during cellular response to calcium starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is greater than normal during a cellular response to calcium starvation." [PomBase:mah] synonym: "increased cell wall alpha-D-glucan level during cellular response to calcium starvation" EXACT [CHEBI:22385, PomBase:mah] synonym: "increased cell wall alpha-glucan accumulation during cellular response to calcium starvation" RELATED [PomBase:mah] synonym: "increased cell wall alpha-glucan level during cellular response to calcium starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell wall alpha-glucan level during cellular response to calcium starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001084 ! increased cell wall alpha-glucan level created_by: midori creation_date: 2014-02-20T14:46:18Z [Term] id: FYPO:0003135 name: normal agglutination def: "A cell adhesion phenotype in which cells adhere to other cells of compatible mating type normally (i.e. agglutination is indistinguishable from wild type)." [PomBase:mah] synonym: "normal agglutination involved in conjugation with cellular fusion" EXACT [GO:0000752] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2014-02-20T14:51:35Z [Term] id: FYPO:0003136 name: excess plasma membrane present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more plasma membrane than normal. Excess plasma membrane may appear as bubble-like structures inside the cell, and may be concentrated in the mating projection during conjugation." [PMID:19627505, PomBase:mah] synonym: "excess mating projection membrane present" NARROW [GO:0070250, PomBase:al, PomBase:vw] synonym: "excess plasma membrane present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "excess plasma membrane present during vegetative growth" EXACT [PomBase:mah] synonym: "increased invagination of the plasma membrane" NARROW [] synonym: "internal membrane bubbles present" RELATED [PMID:19627505, PomBase:vw] is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth created_by: midori creation_date: 2014-02-26T10:31:56Z [Term] id: FYPO:0003137 name: normal mitotic spindle pole body def: "A physical cellular phenotype in which the mitotic spindle pole bodies are normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation." [PomBase:mah] synonym: "normal mitotic SPB" EXACT [PomBase:mah] synonym: "normal mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spindle pole body during mitosis" EXACT [PomBase:vw] synonym: "normal spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-02-26T10:41:05Z [Term] id: FYPO:0003138 name: abnormal ascospore wall morphology def: "A physical cellular phenotype in which the size, shape, or structure of the ascospore wall is abnormal." [PomBase:mah] synonym: "abnormal spore wall morphology" EXACT [PomBase:mah] synonym: "abnormal spore wall organization" RELATED [PomBase:vw] is_a: FYPO:0002946 ! abnormal cell wall relationship: output_of FYPO:0000580 ! abnormal ascospore wall biogenesis created_by: midori creation_date: 2014-02-26T11:13:35Z [Term] id: FYPO:0003139 name: abnormal sporulation resulting in formation of ascus containing anucleate spores def: "A sporulation phenotype that results in the formation of an ascus that contains spore-like bodies that do not contain nuclei." [PMID:8203159, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation ascus containing anucleate spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of asci containing anucleate spores" RELATED [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2014-02-26T11:20:06Z [Term] id: FYPO:0003140 name: obsolete decreased protein tyrosine phosphorylation during cellular response to heat def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to heat." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-tyrosine phosphorylation during cellular response to heat" EXACT [GO:0018108, PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tyrosine phosphorylation during cellular response to heat" EXACT [PomBase:al] synonym: "reduced protein tyrosine phosphorylation during cellular response to heat" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004173 created_by: midori creation_date: 2014-02-26T11:22:56Z [Term] id: FYPO:0003141 name: obsolete decreased protein tyrosine phosphorylation during cellular response to hydrogen peroxide def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydrogen peroxide." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-tyrosine phosphorylation during cellular response to hydrogen peroxide" EXACT [GO:0018108, PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tyrosine phosphorylation during cellular response to hydrogen peroxide" EXACT [PomBase:al] synonym: "reduced protein tyrosine phosphorylation during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002446 created_by: midori creation_date: 2014-02-26T11:24:17Z [Term] id: FYPO:0003142 name: decreased RNA level during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to methyl methanesulfonate" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to MMS" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to methyl methanesulfonate" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-02-26T11:41:17Z [Term] id: FYPO:0003143 name: decreased protein level during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to methyl methanesulfonate is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to MMS" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-02-26T11:43:44Z [Term] id: FYPO:0003144 name: normal protein level during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to methyl methanesulfonate is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2014-02-26T11:46:49Z [Term] id: FYPO:0003145 name: abnormal cell cycle arrest in mitotic prophase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in prophase under conditions where arrest does not normally occur." [PomBase:mah] comment: In cells arrested in prophase, chromosomes are not completely condensed, and may be wholly uncondensed. synonym: "abnormal cell cycle arrest in mitotic prophase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in prophase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in prophase" EXACT [GO:0000088] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2014-02-26T11:51:55Z [Term] id: FYPO:0003146 name: sensitive to hydrostatic pressure def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrostatic pressure." [PomBase:mah] synonym: "decreased growth during cellular response to hydrostatic pressure" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to hydrostatic pressure" EXACT [PomBase:mah] synonym: "hypersensitive to hydrostatic pressure" EXACT [PomBase:mah] synonym: "sensitive to hydrostatic pressure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to hydrostatic pressure during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2014-02-26T11:56:12Z [Term] id: FYPO:0003147 name: abnormal UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity def: "A molecular function phenotype in which the observed rate of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-02-26T11:58:51Z [Term] id: FYPO:0003148 name: increased UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity def: "A molecular function phenotype in which the observed rate of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003147 ! abnormal UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity created_by: midori creation_date: 2014-02-26T11:59:00Z [Term] id: FYPO:0003149 name: decreased chromatin binding during cellular response to methyl methanesulfonate def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased during a cellular response to methyl methanesulfonate. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "decreased chromatin binding during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "decreased chromatin binding during cellular response to MMS" EXACT [PomBase:mah] synonym: "reduced chromatin binding during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2014-02-26T14:50:12Z [Term] id: FYPO:0003150 name: decreased NETO def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased activation of bipolar cell growth" RELATED [PomBase:mah] synonym: "decreased cell growth mode switching, monopolar to bipolar" EXACT [GO:0051523] synonym: "decreased NETO during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased NETO during vegetative growth" EXACT [PomBase:mah] synonym: "decreased new end take-off" EXACT [PomBase:mah] synonym: "decreased switch from monopolar to bipolar cell growth" EXACT [PomBase:mah] synonym: "reduced NETO" EXACT [PomBase:mah] is_a: FYPO:0000147 ! abnormal NETO created_by: midori creation_date: 2014-02-26T15:48:02Z [Term] id: FYPO:0003151 name: decreased protein level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to heat" EXACT [PomBase:mah] synonym: "thermo-sensitive" RELATED [PomBase:vw] synonym: "thermosensitive" RELATED [PomBase:vw] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-02-26T15:56:14Z [Term] id: FYPO:0003152 name: increased protein level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2014-02-26T15:57:07Z [Term] id: FYPO:0003153 name: normal protein level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2014-02-26T15:58:08Z [Term] id: FYPO:0003154 name: abnormal vegetative cell growth def: "A cellular process phenotype in which cell growth is abnormal in the vegetative growth phase of the life cycle. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present." [PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the cell population growth terms, i.e. 'cell population growth phenotype' (FYPO:0000139) and its descendants. is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002862 ! abnormal cell growth created_by: midori creation_date: 2014-02-26T16:03:54Z [Term] id: FYPO:0003155 name: intermittent monopolar cell growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cells grow from one end, and do not grow continuously, but instead oscillate between periods of growth and pauses during which no growth occurs." [PMID:24146635, PomBase:mah] synonym: "intermittent monopolar vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0003154 ! abnormal vegetative cell growth created_by: midori creation_date: 2014-02-26T16:08:07Z [Term] id: FYPO:0003156 name: normal monopolar cell growth def: "A cellular process phenotype in which the monopolar growth of a cell is normal (i.e. indistinguishable from wild type in timing, extent, rate, etc.) in the vegetative growth phase of the life cycle." [PMID:24146635, PomBase:mah] comment: Note that this term refers to growth at the level of any individual cell, and that it specifies only that increase in cell size due to metabolism is normal. Other aspects of the cell's biology may be abnormal, and other abnormalities may affect increase in cell number (population growth). Also see 'cell population growth phenotype' (FYPO:0000139) and its descendants. synonym: "normal monopolar vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0002062 ! normal cell growth created_by: midori creation_date: 2014-02-26T16:13:48Z [Term] id: FYPO:0003157 name: abnormal maintenance of protein location at growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the growing cell tip, but then remains there for a longer or shorter time than normal." [PMID:24146635, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal maintenance of protein localization at growing cell tip" EXACT [GO:0099019] synonym: "abnormal maintenance of protein location at growing cell end" EXACT [PomBase:mah] synonym: "abnormal maintenance of protein location at growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal maintenance of protein location at growing cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "unstable protein localisation to growing cell tip" EXACT [PomBase:mah] synonym: "unstable protein localization to growing cell tip" EXACT [PomBase:mah] is_a: FYPO:0005464 ! abnormal maintenance of protein location at cell tip during vegetative growth created_by: midori creation_date: 2014-02-26T16:34:09Z [Term] id: FYPO:0003158 name: abolished actin cable assembly def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin cables does not occur." [PomBase:mah] synonym: "abolished actin bundling" RELATED [PomBase:vw] synonym: "abolished actin cable assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actin cable assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished formin-nucleated actin cable assembly" EXACT [GO:0070649] synonym: "actin bundling absent" RELATED [PomBase:vw] synonym: "actin cable assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth is_a: FYPO:0002030 ! abnormal actin cable organization created_by: midori creation_date: 2014-02-26T17:05:36Z [Term] id: FYPO:0003159 name: cAMP absent from cell def: "A cell phenotype in which the amount of cyclic AMP (cAMP) measured in a cell is too low to detect." [PomBase:mah] synonym: "cyclic AMP absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001660 ! decreased cellular cAMP level is_a: FYPO:0001888 ! substance absent from cell is_a: FYPO:0006705 ! decreased cellular pentose phosphate level created_by: midori creation_date: 2014-02-26T17:15:41Z [Term] id: FYPO:0003160 name: elongated cell during stationary phase def: "A cell morphology phenotype in which a cell is elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is in a culture in stationary phase." [PomBase:mah] comment: Note that this term is classified as a type of abnormal cell shape, because wild-type cells are never seen with the proportions (length:diameter ratio) observed in elongated cells. Small cells, in contrast, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. synonym: "long cell during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000017 ! elongated cell created_by: midori creation_date: 2014-02-26T17:30:37Z [Term] id: FYPO:0003161 name: RNA absent from cell during vegetative growth alt_id: FYPO:0004509 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "messenger RNA absent from cell" NARROW [PomBase:mah] synonym: "mRNA absent from cell" NARROW [PomBase:mah] synonym: "mRNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mRNA absent from cell during vegetative growth" NARROW [PomBase:mah] synonym: "mRNA transcripts absent from cell" NARROW [PomBase:vw] synonym: "RNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "transcripts absent from cell during vegetative growth" EXACT [PomBase:vw] synonym: "undetectable mRNA level" NARROW [PomBase:mah] synonym: "undetectable RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0001889 ! RNA absent from cell created_by: midori creation_date: 2014-02-26T17:36:19Z [Term] id: FYPO:0003162 name: RNA absent from cell during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to salt stress. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "RNA absent from cell during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA absent from cell during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "transcripts absent from cell during cellular response to salt stress" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0002304 ! decreased RNA level during cellular response to salt stress is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: midori creation_date: 2014-02-26T17:37:56Z [Term] id: FYPO:0003163 name: abnormal nuclease activity def: "A molecular function phenotype in which the observed rate of a nuclease activity is abnormal. All nuclease activities may be abnormal, or a specific nuclease activity may be assayed." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-02-26T17:42:24Z [Term] id: FYPO:0003164 name: abolished nuclease activity def: "A molecular function phenotype in which nuclease activity is absent. All nuclease activities may be absent, or a specific nuclease activity may be assayed." [PomBase:mah] synonym: "nuclease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003163 ! abnormal nuclease activity created_by: midori creation_date: 2014-02-26T17:42:31Z [Term] id: FYPO:0003165 name: cut with abnormal chromosome segregation alt_id: FYPO:0001048 def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis, such that the septum physically divides the nucleus into two parts, and produces inviable daughter cells." [PomBase:jh, PomBase:mah, PomBase:vw] comment: Consider also annotating to 'septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation' (FYPO:0003166) or its descendants, because these phenotypes often co-occur. synonym: "cut with abnormal chromosome segregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut with abnormal chromosome segregation during vegetative growth" EXACT [PomBase:mah] synonym: "cut with mitotic catastrophe" RELATED [PomBase:mah] synonym: "mitotic catastrophe with cut" RELATED [PomBase:mah] synonym: "septation following abnormal chromosome segregation, with septum dividing nucleus" EXACT [PomBase:mah] is_a: FYPO:0000229 ! cut is_a: FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2014-03-05T10:47:49Z [Term] id: FYPO:0003166 name: monoseptate vegetative cell with binucleate and anucleate compartments alt_id: FYPO:0004699 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum, but both nuclei are in a single compartment on one side of the septum. Arises when a cell undergoes septation despite abnormal chromosome segregation, producing inviable daughter cells, and in which the septum forms in a position that partitions both nuclei into one compartment. Cell separation may or may not be completed." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155) or its descendants, because these phenotypes often co-occur. Consider also annotating to 'unequal mitotic sister chromatid segregation' (FYPO:0003241) or one of its descendants, because the abnormal chromosome segregation seen in these mutants often separates DNA into unequal portions. synonym: "abnormal nuclear segregation" RELATED [PomBase:al] synonym: "binucleate monoseptate cell with nuclei grouped" RELATED [PomBase:al] synonym: "monoseptate cell with binucleate and anucleate compartments during vegetative growth" EXACT [PomBase:mah] synonym: "monoseptate vegetative cell with binucleate and anucleate compartments during mitotic cell cycle" RELATED [PomBase:mah] synonym: "monoseptate vegetative cell with binucleate and anucleate compartments following abnormal chromosome segregation" EXACT [PomBase:mah] synonym: "nuclear missegregation" RELATED [PomBase:al] synonym: "septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation" EXACT [PomBase:mah] synonym: "septation following abnormal chromosome segregation, with binucleate cell formation" EXACT [PomBase:mah] synonym: "unequal nuclear partitioning" RELATED [PomBase:vw] is_a: FYPO:0002071 ! mislocalized nucleus during vegetative growth is_a: FYPO:0002342 ! septated vegetative cell relationship: has_part FYPO:0001225 ! monoseptate relationship: has_part FYPO:0002071 ! mislocalized nucleus during vegetative growth created_by: midori creation_date: 2014-03-05T11:09:42Z [Term] id: FYPO:0003167 name: abnormal protein farnesyltransferase activity def: "A molecular function phenotype in which the observed rate of protein farnesyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-03-05T11:47:45Z [Term] id: FYPO:0003168 name: abolished protein farnesyltransferase activity def: "A molecular function phenotype in which protein farnesyltransferase activity is absent." [PomBase:mah] synonym: "protein farnesyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003167 ! abnormal protein farnesyltransferase activity created_by: midori creation_date: 2014-03-05T11:47:54Z [Term] id: FYPO:0003169 name: increased amino acid import during vegetative growth def: "A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a greater extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "increased amino acid import across plasma membrane during vegetative growth" EXACT [GO:0089718] synonym: "increased amino acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased amino acid import into cell during vegetative growth" EXACT [PomBase:al] synonym: "increased amino acid uptake during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2014-03-05T11:52:32Z [Term] id: FYPO:0003170 name: increased arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased arginine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "increased arginine import into cell" EXACT [PomBase:al] synonym: "increased L-arginine import" EXACT [PomBase:mah] synonym: "increased L-arginine import across plasma membrane" EXACT [GO:0097638] synonym: "increased L-arginine uptake" EXACT [PomBase:mah] is_a: FYPO:0001654 ! abnormal arginine import is_a: FYPO:0003169 ! increased amino acid import during vegetative growth created_by: midori creation_date: 2014-03-05T11:53:04Z [Term] id: FYPO:0003171 name: binucleate monoseptate cell with mitotic cell cycle arrest before cell separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and the mitotic cell cycle is arrested after the septum has formed, but before cells have separated." [PomBase:mah] synonym: "binucleate monoseptate cell with cell cycle arrest before cell separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "binucleate monoseptate cell with mitotic cell cycle arrest before cell separation after cytokinesis" EXACT [GO:0000920] synonym: "binucleate monoseptate cell with mitotic cell cycle arrest before cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "binucleate monoseptate cell with mitotic cell cycle arrest before cytokinetic cell separation" EXACT [GO:0000920] synonym: "mitotic cell cycle arrest before cell separation with binucleate monoseptate cell" EXACT [PomBase:vw] synonym: "nuclear division arrest with septation (normal cell length)" EXACT [PomBase:vw] is_a: FYPO:0001222 ! binucleate vegetative cell is_a: FYPO:0002342 ! septated vegetative cell is_a: FYPO:0002888 ! mitotic cell cycle arrest before cell separation relationship: has_part FYPO:0001222 ! binucleate vegetative cell relationship: has_part FYPO:0001225 ! monoseptate relationship: has_part FYPO:0002888 ! mitotic cell cycle arrest before cell separation created_by: midori creation_date: 2014-03-05T14:33:43Z [Term] id: FYPO:0003172 name: abnormal cell cycle arrest in mitotic M phase without septation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase under conditions where arrest does not normally occur, and the cell does not form a septum." [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic M phase without cytokinesis" RELATED [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic M phase without septation, normal cell size" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in M phase without septation" EXACT [PomBase:mah] synonym: "abnormal nuclear division arrest without septation (normal cell length)" EXACT [PomBase:vw] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2014-03-05T15:03:46Z [Term] id: FYPO:0003173 name: abnormal nucleotide-excision repair during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleotide-excision repair is abnormal. Nucleotide-excision repair is a DNA repair process in which a small region of the strand surrounding the damage is removed as an oligonucleotide, and the resulting small gap is filled in by the sequential action of DNA polymerase and DNA ligase." [GO:0006289, PomBase:mah] synonym: "abnormal excision repair during vegetative growth" BROAD [PomBase:mah] synonym: "abnormal NER during vegetative growth" EXACT [GO:0006289] synonym: "abnormal nucleotide-excision repair during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000188 ! abnormal DNA repair during vegetative growth created_by: midori creation_date: 2014-03-05T15:22:23Z [Term] id: FYPO:0003174 name: normal nucleotide-excision repair during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleotide-excision repair is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light. Nucleotide-excision repair is a DNA repair process in which a small region of the strand surrounding the damage is removed as an oligonucleotide, and the resulting small gap is filled in by the sequential action of DNA polymerase and DNA ligase." [GO:0006289, PomBase:mah] synonym: "normal excision repair during cellular response to UV" BROAD [PomBase:mah] synonym: "normal NER during cellular response to UV" EXACT [GO:0006289] synonym: "normal nucleotide-excision repair during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal nucleotide-excision repair during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleotide-excision repair during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-03-05T15:34:33Z [Term] id: FYPO:0003175 name: decreased nucleotide-excision repair during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleotide-excision repair is decreased during a cellular response to ultraviolet light. Nucleotide-excision repair is a DNA repair process in which a small region of the strand surrounding the damage is removed as an oligonucleotide, and the resulting small gap is filled in by the sequential action of DNA polymerase and DNA ligase." [GO:0006289, PomBase:mah] synonym: "decreased excision repair during cellular response to UV" BROAD [PomBase:mah] synonym: "decreased NER during cellular response to UV" EXACT [GO:0006289] synonym: "decreased nucleotide-excision repair during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleotide-excision repair during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "reduced nucleotide-excision repair during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0003173 ! abnormal nucleotide-excision repair during vegetative growth created_by: midori creation_date: 2014-03-05T15:40:08Z [Term] id: FYPO:0003176 name: normal meiotic chromosome segregation def: "A cellular process phenotype in which meiotic chromosome segregation is normal (i.e. indistinguishable from wild type). Meiotic chromosome segregation is the entire process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GO:0045132, PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-03-05T15:46:02Z [Term] id: FYPO:0003177 name: abnormal meiotic homologous chromosome biorientation def: "A cellular process phenotype in which homologous chromosome biorientation is abnormal during meiosis. Homologous chromosome biorientation is the process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, ensuring that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PomBase:mah] synonym: "abnormal homologous chromosome biorientation during meiosis" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome orientation involved in meiotic metaphase I plate congression" EXACT [GO:0031619] is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle relationship: part_of FYPO:0004159 ! abnormal homologous chromosome segregation created_by: midori creation_date: 2014-03-05T16:19:48Z [Term] id: FYPO:0003178 name: normal meiotic sister chromatid segregation def: "A cellular process phenotype in which the organization and subsequent separation of sister chromatids during the second meiotic nuclear division is normal (i.e. indistinguishable from wild type) during meiosis." [GO:0045144, PomBase:mah] synonym: "normal chromosome disjunction at meiosis II" EXACT [PomBase:al] synonym: "normal sister chromatid segregation during meiosis" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-03-05T16:29:02Z [Term] id: FYPO:0003179 name: decreased intragenic meiotic recombination def: "A cellular process phenotype in which the occurrence of intragenic meiotic recombination is decreased. Intragenic meiotic recombination can result in gene conversion events." [PMID:16169489, PomBase:mah] synonym: "decreased meiotic intragenic recombination" EXACT [PMID:16169489, PomBase:al] synonym: "reduced intragenic meiotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2014-03-05T16:35:44Z [Term] id: FYPO:0003181 name: abolished meiotic DNA double-strand break formation def: "A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I does not occur." [GO:0042138, PomBase:mah] synonym: "absent meiotic DNA double-strand break formation" EXACT [PomBase:mah] synonym: "meiotic DNA double-strand break formation abolished" EXACT [PomBase:mah] is_a: FYPO:0003564 ! abnormal meiotic DNA double-strand break formation created_by: midori creation_date: 2014-03-05T16:50:04Z [Term] id: FYPO:0003182 name: sister chromatid nondisjunction at meiosis II alt_id: FYPO:0003605 alt_id: FYPO:0006416 def: "A cellular process phenotype in which sister chromatids are not segregated equally to the two spindle poles in the second meiotic nuclear division." [PMID:10440376, PomBase:mah] synonym: "abnormal chromosome disjunction during meiosis II" EXACT [PomBase:mah] synonym: "abnormal meiotic sister chromatid disjunction" EXACT [PomBase:mah] synonym: "abolished meiotic sister chromatid separation" RELATED [] synonym: "meiosis II nondisjunction" RELATED [PomBase:mah] synonym: "nondisjunction at meiosis II" EXACT [] synonym: "nondisjunction of sister chromatids in meiosis II" EXACT [] synonym: "unequal meiotic chromosome segregation during meiosis II" EXACT [PomBase:mah] synonym: "unequal meiotic sister chromatid segregation in meiosis II" EXACT [] is_a: FYPO:0000925 ! unequal meiotic chromosome segregation is_a: FYPO:0005509 ! abnormal meiotic sister chromatid segregation created_by: midori creation_date: 2014-03-05T16:53:23Z [Term] id: FYPO:0003183 name: normal growth on phleomycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing phleomycin." [PomBase:mah] synonym: "normal cell population growth in presence of phleomycin" EXACT [PomBase:mah] synonym: "normal cell population growth on phleomycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to phleomycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on phleomycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-03-05T16:57:31Z [Term] id: FYPO:0003184 name: normal protein localization to cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoskeleton is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0004096 ! normal protein localization to cytoskeleton created_by: midori creation_date: 2014-03-13T11:35:22Z [Term] id: FYPO:0003185 name: normal protein localization to microtubule cytoskeleton during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to microtubule cytoskeleton during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to microtubule cytoskeleton during interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003184 ! normal protein localization to cytoskeleton during vegetative growth created_by: midori creation_date: 2014-03-13T11:37:33Z [Term] id: FYPO:0003186 name: abolished protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from mitotic spindle" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle abolished" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle abolished" EXACT [PomBase:mah] synonym: "protein localization to spindle abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2014-03-13T11:40:00Z [Term] id: FYPO:0003187 name: protein mislocalized to astral microtubule during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found associated with astral microtubules during mitosis is observed there during mitosis. The protein may or may not normally associate with astral microtubules during other cell cycle phases." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at astral microtubules during mitosis in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to astral microtubule during mitosis" EXACT [PomBase:vw] synonym: "protein mislocalised to astral microtubule during mitosis" EXACT [PomBase:mah] synonym: "protein mislocalized to astral microtubule during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to astral microtubule during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to astral microtubule during mitotic M phase" RELATED [PomBase:mah] synonym: "protein mislocalized to astral microtubule during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2014-03-13T11:49:41Z [Term] id: FYPO:0003188 name: abnormal protein import into nucleus during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the import of protein into the nucleus is abnormal. Import of all proteins or a specific protein may be affected." [PomBase:mah] comment: Encompasses both export of proteins normally retained in the nucleus and nuclear retention of normally exported proteins. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein import into nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport during vegetative growth is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2014-03-13T11:53:16Z [Term] id: FYPO:0003189 name: decreased protein import into nucleus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein import into the nucleus is decreased. Import of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein import into nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein import into nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein import into nucleus" EXACT [PomBase:mah] is_a: FYPO:0003188 ! abnormal protein import into nucleus during vegetative growth created_by: midori creation_date: 2014-03-13T11:53:49Z [Term] id: FYPO:0003190 name: decreased rate of cytoplasmic microtubule depolymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule during interphase of the mitotic cell cycle, occurs at a lower rate, or speed, than normal." [GO:0007019, PomBase:mah] synonym: "decreased interphase microtubule depolymerization rate" EXACT [PomBase:mah] synonym: "decreased rate of cytoplasmic microtubule depolymerization during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased rate of interphase cytoplasmic microtubule depolymerization" EXACT [PomBase:mah] synonym: "decreased rate of interphase microtubule catastrophe" RELATED [PomBase:mah] synonym: "decreased rate of interphase microtubule depolymerisation" EXACT [PomBase:mah] synonym: "decreased rate of interphase microtubule depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of interphase microtubule depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of interphase microtubule shrinkage" RELATED [PomBase:vw] synonym: "increased interphase microtubule stability" RELATED [PomBase:vw] synonym: "reduced rate of interphase microtubule depolymerization" EXACT [PomBase:mah] is_a: FYPO:0000903 ! decreased rate of microtubule depolymerization during vegetative growth created_by: midori creation_date: 2014-03-13T15:13:29Z [Term] id: FYPO:0003191 name: abolished protein localization to microtubule during mitotic interphase, with protein mislocalized to cytoplasmic foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to microtubules does not occur, and the protein is instead visible in one or a few foci or dots in the cytoplasm, during interphase of the mitotic cell cycle." [PMID:18799626, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule during mitotic interphase, with protein mislocalised to cytoplasmic foci" EXACT [PomBase:mah] synonym: "protein localization to microtubule abolished during interphase, with protein mislocalized to cytoplasmic foci, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to microtubule abolished during mitotic interphase, with protein mislocalized to cytoplasmic foci" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2014-03-13T15:45:40Z [Term] id: FYPO:0003192 name: abolished protein localization to nucleus during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleus during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleus during mitotic M-phase" RELATED [PomBase:vw] synonym: "abolished protein localization to nucleus during mitotic nuclear division" EXACT [GO:0140014] synonym: "nuclear exclusion during mitosis" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during mitosis" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: midori creation_date: 2014-03-13T16:03:31Z [Term] id: FYPO:0003193 name: normal rate of microtubule depolymerization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is normal (i.e. indistinguishable from wild type)." [PMID:23051734, PomBase:mah] synonym: "normal microtubule depolymerization rate" EXACT [PomBase:mah] synonym: "normal rate of microtubule catastrophe" RELATED [PomBase:mah] synonym: "normal rate of microtubule depolymerisation" EXACT [PomBase:mah] synonym: "normal rate of microtubule depolymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of microtubule depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of microtubule shrinkage" RELATED [PomBase:vw] is_a: FYPO:0000899 ! normal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2014-03-13T16:05:44Z [Term] id: FYPO:0003194 name: increased rate of microtubule depolymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, occurs at a greater rate, or speed, than normal." [GO:0007019, PomBase:mah] synonym: "decreased microtubule stability during vegetative growth" RELATED [PomBase:vw] synonym: "increased microtubule depolymerization rate during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of microtubule catastrophe during vegetative growth" RELATED [PomBase:mah] synonym: "increased rate of microtubule depolymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of microtubule depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of microtubule shrinkage during vegetative growth" RELATED [PomBase:vw] is_a: FYPO:0007954 ! abnormal rate of microtubule depolymerization during vegetative growth created_by: midori creation_date: 2014-03-13T16:08:23Z [Term] id: FYPO:0003195 name: altered RNA level during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to phosphate starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal RNA level during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "altered cellular RNA level during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered RNA level during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered RNA level during phosphate starvation" EXACT [PomBase:mah] synonym: "altered transcript level during cellular response to phosphate starvation" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2014-03-13T16:42:48Z [Term] id: FYPO:0003196 name: altered RNA level during cellular response to iron ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to iron ion starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal RNA level during cellular response to iron ion starvation" EXACT [PomBase:mah] synonym: "altered cellular RNA level during cellular response to iron ion starvation" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to iron ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered RNA level during cellular response to iron ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to iron starvation" EXACT [PomBase:mah] synonym: "altered RNA level during iron starvation" EXACT [PomBase:mah] synonym: "altered transcript level during cellular response to iron ion starvation" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2014-03-13T16:52:11Z [Term] id: FYPO:0003197 name: altered RNA level during cellular response to copper ion starvation during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to copper ion starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal RNA level during cellular response to copper ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular RNA level during cellular response to copper ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to copper ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered RNA level during cellular response to copper starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered RNA level during copper starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered transcript level during cellular response to copper ion starvation during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2014-03-13T16:54:50Z [Term] id: FYPO:0003198 name: altered RNA level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to osmotic stress. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal RNA level during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "altered cellular RNA level during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered RNA level during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "altered RNA level during osmotic stress" EXACT [PomBase:mah] synonym: "altered transcript level during cellular response to osmotic stress" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2014-03-13T16:55:44Z [Term] id: FYPO:0003199 name: altered RNA level during cellular response to glucose starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to glucose starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abnormal RNA level during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "altered cellular RNA level during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to glucose depletion" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to glucose deprivation" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to glucose limitation" RELATED [PomBase:mah] synonym: "altered RNA level during cellular response to glucose starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered RNA level during cellular response to glucose starvation during vegetative growth" EXACT [PomBase:mah] synonym: "altered RNA level during glucose starvation" EXACT [PomBase:mah] synonym: "altered transcript level during cellular response to glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2014-03-13T16:56:41Z [Term] id: FYPO:0003200 name: normal transcription regulatory region sequence-specific DNA binding during cellular response to phosphate starvation def: "A molecular function phenotype in which occurrence of DNA binding at a transcription regulatory region by a gene product is normal (i.e. indistinguishable from wild type) during a cellular response to phosphate starvation. The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal promoter binding during cellular response to phosphate starvation" RELATED [PomBase:mah] synonym: "normal sequence-specific DNA binding at transcription regulatory region during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "normal transcription regulatory region binding during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "normal transcription regulatory region binding during phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0007382 ! normal transcription regulatory region sequence-specific DNA binding created_by: midori creation_date: 2014-03-13T16:59:44Z [Term] id: FYPO:0003201 name: decreased rate of primary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of primary cell septum biogenesis is decreased." [PomBase:al, PomBase:mah] synonym: "decreased rate of primary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of primary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of primary septum biogenesis" EXACT [PomBase:mah] synonym: "increased duration of primary cell septum biogenesis" RELATED [PomBase:mah] synonym: "reduced rate of primary cell septum biogenesis" EXACT [PomBase:mah] is_a: FYPO:0003890 ! abnormal primary cell septum biogenesis created_by: midori creation_date: 2014-03-13T17:09:40Z [Term] id: FYPO:0003202 name: actomyosin contractile ring contraction uncoupled from septum assembly def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is not spatially and temporally coupled to division septum assembly as in wild type. The edges of the growing septum and the plasma membrane do not remain in contact, and septum assembly may be slower than ring contraction." [PMID:24165938, PomBase:mah] synonym: "actomyosin contractile ring contraction uncoupled from septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actomyosin contractile ring contraction uncoupled from septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinetic contractile ring contraction uncoupled from septum assembly" EXACT [PomBase:vw] is_a: FYPO:0000117 ! abnormal septum assembly is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2014-03-13T17:13:00Z [Term] id: FYPO:0003203 name: curved septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is curved." [PomBase:mah] synonym: "curved septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "curved septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2014-03-13T17:15:03Z [Term] id: FYPO:0003204 name: secondary cell septum absent from cell during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable secondary cell septum." [PomBase:mah] synonym: "absent secondary cell septum during vegetative growth" EXACT [PomBase:mah] synonym: "secondary cell septum absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "secondary septum absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000949 ! aseptate is_a: FYPO:0002455 ! abnormal septum during vegetative growth created_by: midori creation_date: 2014-03-13T17:19:11Z [Term] id: FYPO:0003205 name: decreased primary cell septum thickness def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a primary septum that is thinner than normal." [PomBase:mah] synonym: "decreased primary cell septum thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased primary cell septum thickness during vegetative growth" EXACT [PomBase:mah] synonym: "decreased primary septum thickness" EXACT [PomBase:mah] synonym: "reduced primary cell septum thickness" EXACT [PomBase:mah] synonym: "thin primary septum" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth relationship: output_of FYPO:0003890 ! abnormal primary cell septum biogenesis created_by: midori creation_date: 2014-03-13T17:26:49Z [Term] id: FYPO:0003206 name: decreased protein-protein interaction during cellular response to salt stress def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to salt stress. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction during salt stress" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction in response to salt stress" RELATED [PomBase:al] synonym: "reduced protein-protein interaction during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction created_by: midori creation_date: 2014-03-13T17:29:53Z [Term] id: FYPO:0003207 name: decreased protein-protein interaction during cellular response to hydrogen peroxide def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hydrogen peroxide. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction in response to hydrogen peroxide" RELATED [PomBase:al] synonym: "reduced protein-protein interaction during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction created_by: midori creation_date: 2014-03-13T17:31:46Z [Term] id: FYPO:0003208 name: decreased protein localization to cell tip, with protein distributed in plasma membrane or cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased, and an increased amount of the protein is instead detected distributed throughout the plasma membrane and/or cell cortex." [PMID:22891259, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell tip, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to cell end, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to cell tip, with protein distributed in plasma membrane or cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell tip, with protein distributed in plasma membrane or cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cell tip, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] is_a: FYPO:0001586 ! decreased protein localization to cell tip during vegetative growth created_by: midori creation_date: 2014-03-19T10:35:23Z [Term] id: FYPO:0003209 name: abolished protein localization to cell tip, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell tip, with protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to cell end, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cell tip, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cell tip abolished, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0001585 ! abolished protein localization to cell tip during vegetative growth created_by: midori creation_date: 2014-03-19T10:46:02Z [Term] id: FYPO:0003210 name: mislocalized, misoriented septum def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum that is in an abnormal location and is not perpendicular to the long axis of the cell. The normal location is at the midpoint of the long axis of the cell." [PomBase:mah] comment: Note that the location of the septum is determined by the location of the contractile ring, which in turn is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. Consider also annotating to 'mislocalized actomyosin contractile ring' (FYPO:0001369) because if the contractile ring forms in an abnormal location, the septum will also do so. synonym: "abnormal septum localization and orientation" RELATED [PomBase:mah] synonym: "abnormal septum location and orientation" EXACT [PomBase:mah] synonym: "abnormal septum position and orientation" EXACT [PomBase:mah] synonym: "abnormal septum positioning and orientation" RELATED [PomBase:mah] synonym: "asymmetric, misoriented septum" EXACT [PomBase:mah] synonym: "asymmetrically located, misoriented septum" EXACT [PomBase:mah] synonym: "mislocalised, misoriented septum" EXACT [PomBase:mah] synonym: "mislocalized, misoriented septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized, misoriented septum during vegetative growth" EXACT [PomBase:mah] synonym: "misplaced, misoriented septum" EXACT [PomBase:vw] is_a: FYPO:0000339 ! mislocalized septum during vegetative growth is_a: FYPO:0001390 ! misoriented septum during vegetative growth created_by: midori creation_date: 2014-03-19T10:50:08Z [Term] id: FYPO:0003211 name: abnormal secondary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which secondary cell septum biogenesis is abnormal. Secondary cell septum biogenesis results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of the secondary cell septum during cytokinesis." [PomBase:mah] comment: Consider also annotating to 'abnormal contractile ring localization' (FYPO:0000033) because if the contractile ring forms in an abnormal location, the septum will also do so. The positions of both the contractile ring and the septum are determined by the processes that select the site of cell division. synonym: "abnormal secondary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal secondary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal secondary cell septum formation" RELATED [PomBase:mah] synonym: "abnormal secondary cell septum synthesis" RELATED [PomBase:mah] synonym: "abnormal secondary septum biogenesis" EXACT [PomBase:mah] is_a: FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2014-03-19T10:58:05Z [Term] id: FYPO:0003212 name: kinked septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is kinked, i.e. has multiple angles along its length." [PMID:22891259, PomBase:mah] synonym: "kinked septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "kinked septum during vegetative growth" EXACT [PomBase:mah] synonym: "twisted septum" RELATED [PATO:0001798, PMID:22891259] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2014-03-19T11:10:26Z [Term] id: FYPO:0003213 name: explosive cytokinetic cell separation resulting in vegetative cell lysis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation is instantaneous and asymmetrical, with a ripped primary septum. Explosive cell separation takes a few seconds (rather than 5-6 minutes as in wild type) and involves asymmetrical degradation and/or breakage of the septum edging followed by an abrupt tear of a weak primary septum and an instantaneous curvature of the secondary septum." [PMID:22891259, PomBase:mah] synonym: "side-by-side cells" RELATED [PMID:10087262] synonym: "side-explosive cell separation" EXACT [PMID:22891259] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis relationship: has_output FYPO:0003440 ! cell lysis during cytokinesis created_by: midori creation_date: 2014-03-19T11:16:27Z [Term] id: FYPO:0003214 name: normal protein phosphorylation during cellular response to glucose starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to glucose starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal protein phosphorylation during cellular response to glucose depletion" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to glucose deprivation" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to glucose limitation" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to glucose starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to glucose starvation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-03-19T11:26:01Z [Term] id: FYPO:0003215 name: normal protein-protein interaction during cellular response to hydrogen peroxide def: "A molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is tested in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal protein binding during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "normal protein-protein interaction during cellular response to H2O2" EXACT [PomBase:mah] is_a: FYPO:0000703 ! normal protein-protein interaction created_by: midori creation_date: 2014-03-19T11:28:46Z [Term] id: FYPO:0003216 name: decreased chromatin silencing at rDNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeat regions is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased chromatin silencing at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at ribosomal DNA" EXACT [PomBase:mah] synonym: "reduced chromatin silencing at rDNA" EXACT [PomBase:mah] is_a: FYPO:0000206 ! abnormal chromatin silencing at rDNA is_a: FYPO:0002353 ! decreased chromatin silencing created_by: midori creation_date: 2014-03-19T11:38:08Z [Term] id: FYPO:0003217 name: decreased chromatin silencing at centromere central core def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the chromatin silencing at the central core of the centromeric regions is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes at the centromere central core may reflect the assembly or maintenance of CENP-A-containing chromatin. See the GO cellular component term 'CENP-A containing chromatin' (GO:0061638), and the biological process term 'CENP-A containing chromatin organization' (GO:0061641). synonym: "decreased chromatin silencing at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "decreased negative regulation of transcription at centromere central core" RELATED [GO:0045892] synonym: "decreased transcriptional repression at centromere central core" RELATED [PomBase:mah] synonym: "reduced chromatin silencing at centromere central core" EXACT [PomBase:mah] is_a: FYPO:0000640 ! abnormal chromatin silencing at centromere central core created_by: midori creation_date: 2014-03-19T11:40:22Z [Term] id: FYPO:0003218 name: abolished tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the modification of a wobble base uridine residue in a tRNA to 5-methoxycarbonylmethyl-2-thiouridine is abolished." [GO:0002926, PomBase:mah] synonym: "abolished mcm5s2U34 biosynthesis" EXACT [GO:0002926, PomBase:mah] synonym: "abolished thiolation and methoxycarbonylmethylation at tRNA U34" EXACT [PomBase:al] synonym: "abolished tRNA U34 5-methoxycarbonylmethyl-2-thiouridine biosynthesis" EXACT [GO:0002926, PomBase:mah] synonym: "abolished tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis during vegetative growth" EXACT [PomBase:mah] synonym: "tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis abolished" EXACT [PomBase:mah] is_a: FYPO:0008344 ! abolished tRNA modification created_by: midori creation_date: 2014-03-19T11:54:10Z [Term] id: FYPO:0003219 name: obsolete decreased histone H3-K9K14 acetylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 9 and 14 of histone H3 occurs to a lower extent than normal." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "decreased histone H3 K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 and K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone lysine H3 K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0001442 consider: FYPO:0001458 created_by: midori creation_date: 2014-03-19T14:09:21Z [Term] id: FYPO:0003220 name: obsolete normal histone H3-K9K14 acetylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 9 and 14 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "normal histone H3 K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 and K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone lysine H3 K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0003223 consider: FYPO:0003224 created_by: midori creation_date: 2014-03-19T14:13:02Z [Term] id: FYPO:0003221 name: normal histone acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002600 ! normal histone modification during vegetative growth created_by: midori creation_date: 2014-03-19T14:13:37Z [Term] id: FYPO:0003222 name: sensitive to zearalenone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zearalenone. Cells stop growing (and may die) at a concentration of zearalenone that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to zearalenone" EXACT [PomBase:mah] synonym: "sensitive to ZEA" EXACT [PomBase:al] synonym: "sensitive to zearalenone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to zearalenone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-03-19T14:19:37Z [Term] id: FYPO:0003223 name: normal histone H3-K9 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H3 K9 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003221 ! normal histone acetylation during vegetative growth created_by: midori creation_date: 2014-03-19T14:36:25Z [Term] id: FYPO:0003224 name: normal histone H3-K14 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H3 K14 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003221 ! normal histone acetylation during vegetative growth created_by: midori creation_date: 2014-03-19T14:39:12Z [Term] id: FYPO:0003225 name: normal rate of microtubule polymerization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of microtubule polymerization, i.e. the addition of tubulin dimers to a microtubule, is normal (i.e. indistinguishable from wild type)." [PMID:23051734, PomBase:mah] synonym: "normal microtubule polymerization rate" EXACT [PomBase:mah] synonym: "normal rate of microtubule growth" RELATED [PomBase:vw] synonym: "normal rate of microtubule polymerisation" EXACT [PomBase:mah] synonym: "normal rate of microtubule polymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000899 ! normal microtubule cytoskeleton organization during vegetative growth is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2014-03-25T13:42:28Z [Term] id: FYPO:0003226 name: delayed onset of protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle begins later than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein mitotic spindle to mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to mitotic spindle" EXACT [PomBase:mah] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2014-03-25T13:51:32Z [Term] id: FYPO:0003227 name: interphase microtubules present during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the long cytoplasmic microtubules characteristic of interphase cells remain present after mitosis begins and the mitotic spindle forms." [PMID:18799626, PomBase:mah] synonym: "interphase cytoplasmic microtubules present during mitosis" EXACT [PomBase:mah] synonym: "interphase microtubules present during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "interphase microtubules present during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "interphase microtubules present during mitotic M phase" RELATED [PomBase:mah] synonym: "interphase microtubules present during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2014-03-25T13:59:34Z [Term] id: FYPO:0003228 name: abolished protein oxidation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the oxidation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein oxidation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abolished protein oxidation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein oxidation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein oxidation abolished during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth created_by: midori creation_date: 2014-03-25T14:29:42Z [Term] id: FYPO:0003229 name: abnormal hydrogen peroxide catabolism def: "A cellular process phenotype in which the chemical breakdown of hydrogen peroxide is abnormal." [GO:0042744, PomBase:mah] synonym: "abnormal H2O2 catabolic process" EXACT [GO:0042744] synonym: "abnormal H2O2 catabolism" EXACT [GO:0042744] synonym: "abnormal hydrogen peroxide catabolic process" EXACT [GO:0042744] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2014-03-25T14:33:16Z [Term] id: FYPO:0003230 name: decreased histone H3-K9 methylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin islands occurs to a lower extent than normal." [PMID:24210919, PomBase:mah] synonym: "decreased histone H3 K9 methylation at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9me at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation at heterochromatin island during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-03-25T15:38:16Z [Term] id: FYPO:0003231 name: decreased histone H3-K9 methylation at heterochromatin domain during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin domains occurs to a lower extent than normal." [PMID:24210919, PomBase:mah] synonym: "decreased histone H3 K9 methylation at heterochromatin domain during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation at heterochromatin domain during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 methylation at HOODs during vegetative growth" EXACT [PMID:24210919] synonym: "decreased histone H3K9me at heterochromatin domain during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation at heterochromatin domain during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation at heterochromatin domain during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-03-25T15:47:37Z [Term] id: FYPO:0003232 name: normal histone H3-K9 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "normal histone H3-K9 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "normal histone lysine H3 K9 methylation during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2014-03-25T17:09:55Z [Term] id: FYPO:0003233 name: normal histone H3-K9 methylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin islands is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 methylation at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "normal histone H3-K9 methylation at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "normal histone lysine H3 K9 methylation at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-03-25T17:11:22Z [Term] id: FYPO:0003234 name: normal histone H3-K9 methylation at heterochromatin domain during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin domains is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 methylation at heterochromatin domain during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone H3-K9 methylation at heterochromatin domain during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 methylation at HOOD during vegetative growth" EXACT [PMID:24210919] synonym: "normal histone H3K9me at heterochromatin domain during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone lysine H3 K9 methylation at heterochromatin domain during vegetative growth" EXACT [GO:0010452, PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-03-25T17:12:02Z [Term] id: FYPO:0003235 name: normal histone H3-K9 methylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at centromere outer repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 methylation at centromere outer repeat during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone H3-K9 methylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 methylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 methylation at centromeric outer repeat region during vegetative growth" EXACT [PMID:24210919] synonym: "normal histone H3-K9 methylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3-K9 methylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3K9me at centromere outer repeat during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone lysine H3 K9 methylation at centromere outer repeat during vegetative growth" EXACT [GO:0010452, PomBase:mah] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth created_by: midori creation_date: 2014-03-25T17:15:41Z [Term] id: FYPO:0003236 name: decreased transposable element-derived small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell is lower than normal." [PMID:24095277, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased accumulation of transposable element-derived small RNAs" RELATED [PomBase:vw] synonym: "decreased transposable element-derived small RNA accumulation" RELATED [PomBase:mah] synonym: "decreased transposable element-derived small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transposable element-derived small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transposable element-derived small transcript level" EXACT [PomBase:mah] synonym: "decreased transposon-derived small RNA level" EXACT [PomBase:mah] synonym: "reduced transposable element-derived small RNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-03-25T17:19:03Z [Term] id: FYPO:0003237 name: increased RNA splicing at cryptic splice sites def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of RNA primary transcripts at sites that are not normally frequently used (or not spliced at all) is increased." [PMID:24210919, PomBase:mah] synonym: "increased RNA splicing at cryptic splice sites during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA splicing at cryptic splice sites during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA splicing of cryptic introns" EXACT [PMID:24210919] is_a: FYPO:0002916 ! increased RNA splicing, via spliceosome created_by: midori creation_date: 2014-03-25T17:20:03Z [Term] id: FYPO:0003238 name: decreased anaerobic cell population growth def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under anaerobic conditions." [PomBase:mah] synonym: "decreased anaerobic vegetative cell population growth" EXACT [PomBase:mah] synonym: "reduced anaerobic cell population growth" EXACT [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2014-03-25T17:25:09Z [Term] id: FYPO:0003239 name: abnormal phosphodiesterase I activity def: "A molecular function phenotype in which the observed rate of phosphodiesterase I activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-03-25T17:27:12Z [Term] id: FYPO:0003240 name: decreased phosphodiesterase I activity def: "A molecular function phenotype in which the observed rate of phosphodiesterase I activity is decreased." [PomBase:mah] synonym: "reduced phosphodiesterase I activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003239 ! abnormal phosphodiesterase I activity created_by: midori creation_date: 2014-03-25T17:27:18Z [Term] id: FYPO:0003241 name: unequal mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation fails to separate chromosomes into two equal masses. Unequal mitotic sister chromatid separation may be complete, with two distinct unequal DNA masses located at or near the ends of an elongated mitotic spindle, or incomplete." [PomBase:mah] comment: Consider also annotating to 'abnormal sister chromatid biorientation' (FYPO:0000326) because a problem with biorientation usually results in unequal chromosome segregation. synonym: "chromosome missegregation" EXACT [PomBase:vw] synonym: "mitotic chromosome nondisjunction" EXACT [PomBase:mah] synonym: "unequal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "unequal mitotic sister chromatid segregation during vegetative growth" EXACT [PomBase:mah] synonym: "unequal mitotic sister chromatid separation" RELATED [PomBase:mah] synonym: "unequal sister chromatid segregation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_output FYPO:0004321 ! altered DNA level during vegetative growth created_by: midori creation_date: 2014-03-25T17:29:06Z [Term] id: FYPO:0003242 name: decreased splicing of mRNA introns with low A/U content def: "A cellular process phenotype in which the occurrence of mRNA splicing via the spliceosome is decreased, where introns have low A/U content." [PMID:23754748, PomBase:mah] synonym: "decreased mRNA splicing, via spliceosome, introns with low A/U content" EXACT [PomBase:mah] synonym: "decreased nuclear mRNA splicing, via spliceosome, introns with low A/U content" EXACT [PomBase:mah] synonym: "decreased splicing of mRNA introns with low A/U content" BROAD [PomBase:al] synonym: "decreased splicing of mRNA introns with low A/U content during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased splicing of mRNA introns with low A/U content during vegetative growth" EXACT [PomBase:mah] synonym: "reduced splicing of mRNA introns with low A/U content" EXACT [PomBase:mah] is_a: FYPO:0003244 ! decreased mRNA splicing, via spliceosome, intron-specific created_by: midori creation_date: 2014-03-28T13:49:03Z [Term] id: FYPO:0003243 name: decreased splicing of long introns def: "A cellular process phenotype observed in the vegetative growth the occurrence of splicing of introns longer than about 45 nucleotides is decreased." [PMID:23754748, PomBase:mah] synonym: "decreased splicing of long introns during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased splicing of long introns during vegetative growth" EXACT [PomBase:mah] synonym: "reduced splicing of long introns" EXACT [PomBase:mah] is_a: FYPO:0003040 ! decreased RNA splicing, via splicosome created_by: midori creation_date: 2014-03-28T13:55:19Z [Term] id: FYPO:0003244 name: decreased mRNA splicing, via spliceosome, intron-specific def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome takes place normally for some, but is decreased for other, specific introns." [PMID:23754748] synonym: "differential pre-mRNA splicing defects" EXACT [PMID:20400941] synonym: "intron-specific abnormal mRNA splicing, via spliceosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "intron-specific abnormal mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] synonym: "intron-specific abnormal nuclear mRNA splicing, via spliceosome" EXACT [PomBase:mah] synonym: "intron-specific mRNA splicing defects" EXACT [PomBase:al] is_a: FYPO:0003029 ! decreased mRNA splicing, via spliceosome created_by: midori creation_date: 2014-03-28T14:09:33Z [Term] id: FYPO:0003245 name: telophase nuclear clustering def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the daughter nuclei formed by mitosis cluster in the middle of the cell during telophase. Normally, daughter nuclei move away from the cell division site during mitotic telophase." [PMID:23087209, PomBase:mah] comment: This phenotype may be observed when cytokinesis fails. synonym: "daughter nuclei clustered at cell division site during mitotic telophase" EXACT [PomBase:vw] synonym: "kissing nuclei" EXACT [PMID:23087209] synonym: "nuclear clustering during mitotic telophase" EXACT [PomBase:mah] synonym: "nuclei clustered at cell division site during mitotic telophase" EXACT [PomBase:vw] synonym: "telophase nuclear clustering during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0002071 ! mislocalized nucleus during vegetative growth relationship: output_of FYPO:0000417 ! abolished cytokinesis created_by: midori creation_date: 2014-03-28T14:35:02Z [Term] id: FYPO:0003246 name: normal mitotic S phase progression def: "A cellular process phenotype in which progression through S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitotic cell cycle progression in S" EXACT [PomBase:mah] synonym: "normal mitotic S phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "normal S phase progression during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2014-03-28T15:00:02Z [Term] id: FYPO:0003247 name: abolished histone H3 binding def: "A molecular function phenotype in which occurrence of histone H3 binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished protein-histone H3 interaction" EXACT [PomBase:mah] synonym: "histone H3 binding abolished" EXACT [PomBase:mah] is_a: FYPO:0007157 ! abnormal histone binding created_by: midori creation_date: 2014-03-28T15:03:01Z [Term] id: FYPO:0003248 name: increased level of histone H3 at centromere inner repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured at centromere inner repeat regions is higher than normal." [PMID:22291963, PomBase:mah] synonym: "increased level of histone H3 at centromere imr" EXACT [PomBase:mah, SO:0001798] synonym: "increased level of histone H3 at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of histone H3 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2014-03-28T15:10:35Z [Term] id: FYPO:0003249 name: decreased level of histone H3 at dh repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured at centromeric dh repeat regions is lower than normal." [PMID:22291963, PomBase:mah] synonym: "decreased level of histone H3 at dh repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of histone H3 at dh repeat during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of histone H3 at dh repeat" EXACT [PomBase:mah] is_a: FYPO:0004578 ! decreased level of histone H3 in cell created_by: midori creation_date: 2014-03-28T15:14:44Z [Term] id: FYPO:0003250 name: premature septum assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly begins earlier than normal, e.g. before metaphase is complete." [PMID:23394829, PomBase:mah] synonym: "advanced septum assembly" EXACT [PomBase:mah] synonym: "ectopic metaphase septum assembly" RELATED [PMID:23394829] synonym: "premature division septum assembly" EXACT [GO:0000917, PomBase:mah] synonym: "premature division septum formation involved in mitotic cytokinesis" EXACT [PomBase:mah] synonym: "premature septation" BROAD [GO:0000917, PomBase:mah] synonym: "premature septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature septum assembly during vegetative growth" EXACT [PomBase:mah] synonym: "premature septum formation" RELATED [PomBase:mah] is_a: FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2014-03-28T15:22:36Z [Term] id: FYPO:0003251 name: decreased transcription from SRE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more sterol regulatory elements (SREs) occurs to a lower extent than normal." [PMID:24327658, PomBase:mah] synonym: "decreased transcription from SRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from SRE promoter during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription from SRE-containing promoter" EXACT [PomBase:mah] synonym: "decreased transcription from sterol regulatory element-containing promoter" EXACT [PomBase:mah, SO:1861] synonym: "reduced transcription from SRE promoter" EXACT [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2014-03-28T15:30:32Z [Term] id: FYPO:0003252 name: abolished cell population growth on proline nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-proline as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with proline as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on proline nitrogen source" BROAD [PomBase:mah] synonym: "abolished proline utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on proline nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on proline nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2014-04-01T11:30:43Z [Term] id: FYPO:0003253 name: abolished amino acid import during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of one or more amino acids into the cell is abolished." [PomBase:mah] synonym: "abolished amino acid import across plasma membrane during vegetative growth" EXACT [GO:0089718] synonym: "abolished amino acid import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished amino acid import into cell" EXACT [PomBase:al] synonym: "abolished amino acid uptake" EXACT [PomBase:mah] synonym: "amino acid import abolished" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2014-04-01T11:42:23Z [Term] id: FYPO:0003254 name: abolished arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell is abolished." [PomBase:mah] synonym: "abolished arginine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "abolished arginine import into cell" EXACT [PomBase:al] synonym: "abolished arginine uptake" EXACT [PomBase:mah] synonym: "abolished L-arginine import across plasma membrane" EXACT [GO:0097638] synonym: "abolished L-arginine import into cell" EXACT [PomBase:mah] synonym: "arginine import abolished" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2014-04-01T11:53:36Z [Term] id: FYPO:0003255 name: abolished proline import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell is abolished." [PomBase:mah] synonym: "abolished L-proline import across plasma membrane" EXACT [GO:1904271] synonym: "abolished L-proline import into cell" NARROW [PomBase:mah] synonym: "abolished proline import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished proline import during vegetative growth" EXACT [PomBase:mah] synonym: "abolished proline import into cell" EXACT [PomBase:al] synonym: "abolished proline uptake" EXACT [PomBase:mah] synonym: "proline import abolished" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2014-04-01T11:54:49Z [Term] id: FYPO:0003256 name: abnormal proline import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-proline import" EXACT [PomBase:mah] synonym: "abnormal L-proline import across plasma membrane" EXACT [GO:1904271] synonym: "abnormal proline import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal proline import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal proline import into cell" EXACT [PomBase:al] synonym: "abnormal proline uptake" EXACT [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2014-04-01T11:59:03Z [Term] id: FYPO:0003257 name: decreased proline import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-proline import" EXACT [PomBase:mah] synonym: "decreased L-proline import across plasma membrane" EXACT [GO:1904271] synonym: "decreased proline import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased proline import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased proline import into cell" EXACT [PomBase:al] synonym: "decreased proline uptake" EXACT [PomBase:mah] synonym: "reduced proline import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0003256 ! abnormal proline import created_by: midori creation_date: 2014-04-01T11:59:16Z [Term] id: FYPO:0003258 name: increased proline import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased L-proline import" NARROW [PomBase:mah] synonym: "increased L-proline import across plasma membrane" EXACT [GO:1904271] synonym: "increased proline import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased proline import during vegetative growth" EXACT [PomBase:mah] synonym: "increased proline import into cell" EXACT [PomBase:al] synonym: "increased proline uptake" EXACT [PomBase:mah] is_a: FYPO:0003169 ! increased amino acid import during vegetative growth is_a: FYPO:0003256 ! abnormal proline import created_by: midori creation_date: 2014-04-01T11:59:37Z [Term] id: FYPO:0003259 name: normal proline import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal L-proline import" EXACT [PomBase:mah] synonym: "normal L-proline import across plasma membrane" EXACT [GO:1904271] synonym: "normal proline import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal proline import during vegetative growth" EXACT [PomBase:mah] synonym: "normal proline import into cell" EXACT [PomBase:al] synonym: "normal proline uptake" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2014-04-01T14:27:36Z [Term] id: FYPO:0003260 name: decreased RNA splicing at cryptic splice sites def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of RNA primary transcripts at sites that are not normally frequently used is decreased." [PMID:24210919, PomBase:mah] synonym: "decreased RNA splicing at cryptic splice sites during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA splicing at cryptic splice sites during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA splicing of cryptic introns" EXACT [PMID:24210919] synonym: "reduced RNA splicing at cryptic splice sites" EXACT [PomBase:mah] is_a: FYPO:0003040 ! decreased RNA splicing, via splicosome created_by: midori creation_date: 2014-04-01T14:33:51Z [Term] id: FYPO:0003261 name: obsolete decreased small RNA level def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA measured in a cell is lower than normal. All types of small RNA, a particular RNA type, or a specific small RNA may be affected." [PMID:24095277, PomBase:mah] comment: This term was made obsolete because "small RNA" is not specific enough to indicate what type(s) of RNA is affected. synonym: "decreased accumulation of small RNAs" RELATED [PomBase:vw] synonym: "decreased small RNA accumulation" RELATED [PomBase:mah] synonym: "decreased small RNA level" RELATED [PomBase:mah] synonym: "decreased small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced small RNA level" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2014-04-01T14:36:05Z [Term] id: FYPO:0003262 name: obsolete increased small RNA level def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA measured in a cell is greater than normal. All types of small RNA, a particular RNA type, or a specific small RNA may be affected." [PMID:24095277, PomBase:mah] comment: This term was made obsolete because "small RNA" is not specific enough to indicate what type(s) of RNA is affected. synonym: "increased accumulation of small RNAs" RELATED [PomBase:vw] synonym: "increased small RNA accumulation" RELATED [PomBase:mah] synonym: "increased small RNA level" RELATED [PomBase:mah] synonym: "increased small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced small RNA level" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2014-04-01T14:38:04Z [Term] id: FYPO:0003263 name: abnormal sporulation resulting in formation of ascus with more than four spores def: "A sporulation phenotype in which asci that contain more than four, and up to eight, spores form following conjugation and subsequent sporulation." [PMID:24196444, PomBase:mah, PomBase:vw] synonym: "8-spored asci" RELATED [PomBase:vw] synonym: "abnormal ascospore formation resulting in formation of asci with more than four spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of asci with more than four spores" EXACT [PomBase:mah] synonym: "asci with increased number of spores" EXACT [PomBase:vw] synonym: "eight-spored asci" RELATED [PomBase:vw] is_a: FYPO:0001894 ! abnormal sporulation resulting in formation of ascus with more or fewer than four spores created_by: midori creation_date: 2014-04-01T16:23:32Z [Term] id: FYPO:0003264 name: overlapping meiosis I spindles def: "A spindle phenotype in which the meiotic spindles in adjacent dividing nuclei overlap during meiosis I. The order of nuclei in the resulting ascus differs from normal as a result." [PMID:24196444, PomBase:mah] synonym: "overlapping spindles at meiosis I" EXACT [PomBase:vw] synonym: "overlapping spindles during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2014-04-02T14:41:20Z [Term] id: FYPO:0003265 name: normal alpha,alpha-trehalase activity increase during cellular response to heat stress def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of a heat stress." [PomBase:mah] synonym: "normal increase in trehalase activity in response to heat stress" EXACT [PomBase:al] synonym: "normal neutral trehalase activity increase during cellular response to heat stress" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity increase during cellular response to heat stress" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001480 ! normal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-04-02T14:50:31Z [Term] id: FYPO:0003266 name: normal alpha,alpha-trehalase activity during cellular response to nutrient def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is normal (i.e. indistinguishable from wild type) during a cellular response to nutrient." [PomBase:mah] synonym: "normal alpha,alpha-trehalase activity in response to nutrient" EXACT [PomBase:al] synonym: "normal neutral trehalase activity during cellular response to nutrient" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity during cellular response to nutrient" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001480 ! normal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-04-02T14:51:45Z [Term] id: FYPO:0003267 name: normal acid phosphatase activity def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-04-02T14:57:53Z [Term] id: FYPO:0003268 name: decreased rate of mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased." [PomBase:mah] synonym: "decreased rate of mitotic spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of spindle elongation during mitosis" EXACT [PomBase:mah] synonym: "reduced rate of mitotic spindle elongation" EXACT [PomBase:mah] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation created_by: midori creation_date: 2014-04-02T15:03:47Z [Term] id: FYPO:0003269 name: abolished protein localization to microtubule during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubules does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from microtubule" RELATED [PomBase:mah] synonym: "protein localization to microtubule abolished" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2014-04-02T15:25:45Z [Term] id: FYPO:0003270 name: growth auxotrophic for glutathione def: "Auxotrophy in which a cell is unable to synthesize glutathione, and therefore requires glutathione in the medium for vegetative cell growth." [PomBase:mah] synonym: "glutathione auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for glutathione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for glutathione during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2014-04-02T15:31:53Z [Term] id: FYPO:0003271 name: decreased cell population growth on methionine sulfur source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-methionine as the sole sulfur source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased cell population growth on methionine sulphur source" EXACT [PomBase:mah] synonym: "decreased growth on methionine sulfur source" BROAD [PomBase:mah] synonym: "decreased methionine utilization" RELATED [PomBase:mah] synonym: "decreased vegetative cell population growth on methionine sulfur source" EXACT [PomBase:mah] synonym: "reduced cell population growth on methionine sulfur source" EXACT [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2014-04-02T15:32:50Z [Term] id: FYPO:0003272 name: normal growth on sodium hypochlorite def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium hypochlorite." [PomBase:mah] synonym: "normal cell population growth in presence of sodium hypochlorite" EXACT [PomBase:mah] synonym: "normal cell population growth on NaOCl" EXACT [PomBase:al] synonym: "normal cell population growth on sodium hypochlorite" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to sodium hypochlorite" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on sodium hypochlorite" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-04-02T15:36:59Z [Term] id: FYPO:0003273 name: normal growth on nitrite def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nitrite ions." [PomBase:mah] synonym: "normal cell population growth in presence of nitrite" EXACT [PomBase:mah] synonym: "normal cell population growth on nitrite" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on nitrite ion" EXACT [PomBase:mah] synonym: "normal cellular response to nitrite" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on nitrite ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on nitrite" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-04-02T15:41:59Z [Term] id: FYPO:0003274 name: normal growth on GSNO def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing S-nitrosoglutathione (GSNO)." [PomBase:mah] synonym: "normal cell population growth in presence of GSNO" EXACT [PomBase:mah] synonym: "normal cell population growth on GSNO" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on S-nitrosoglutathione" EXACT [CHEBI:50091] synonym: "normal cellular response to GSNO" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on GSNO" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-04-02T15:42:47Z [Term] id: FYPO:0003275 name: sensitive to nitrite def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nitrite ions. Cells stop growing (and may die) at a concentration of nitrite ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nitrite" EXACT [PomBase:mah] synonym: "sensitive to nitrite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nitrite during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to nitrite ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-04-02T15:59:21Z [Term] id: FYPO:0003276 name: sensitive to sodium hypochlorite def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium hypochlorite. Cells stop growing (and may die) at a concentration of sodium hypochlorite that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium hypochlorite" EXACT [PomBase:mah] synonym: "sensitive to NaOCl" EXACT [PomBase:al] synonym: "sensitive to sodium hypochlorite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium hypochlorite during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-04-02T16:01:18Z [Term] id: FYPO:0003277 name: abolished protein localization to microtubule during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubules does not occur during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to microtubule during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to microtubule during mitotic nuclear division" EXACT [GO:0140014] synonym: "protein absent from microtubule during mitosis" RELATED [PomBase:mah] synonym: "protein localization to microtubule abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0003269 ! abolished protein localization to microtubule during vegetative growth created_by: midori creation_date: 2014-04-02T16:07:17Z [Term] id: FYPO:0003278 name: abnormal plasma membrane during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position, morphology, or physical characteristics of all or part of the plasma membrane is abnormal." [PomBase:mah] comment: Note that an abnormal plasma membrane organization process may, but does not necessarily, result in an abnormal plasma membrane. synonym: "abnormal plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0000813 ! abnormal plasma membrane organization created_by: midori creation_date: 2014-04-02T16:11:20Z [Term] id: FYPO:0003279 name: excess Golgi cisternae present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more Golgi cisternae than normal. Golgi cisternae are the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex." [GO:0031985, PomBase:mah] synonym: "accumulation of Golgi cisternae" EXACT [PomBase:vw] synonym: "excess Golgi cisternae present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "excess Golgi cisternae present during vegetative growth" EXACT [PomBase:mah] synonym: "Golgi cisternae present in greater amount" EXACT [PomBase:mah] is_a: FYPO:0000349 ! abnormal Golgi morphology is_a: FYPO:0000354 ! abnormal endoplasmic reticulum morphology created_by: midori creation_date: 2014-04-03T14:07:34Z [Term] id: FYPO:0003280 name: decreased RNA level during cellular response to copper ion starvation during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to copper ion starvation during vegetative growth" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to copper ion starvation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper ion depletion during vegetative growth" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to copper ion deprivation during vegetative growth" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to copper ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during copper ion starvation" EXACT [PomBase:al] synonym: "decreased transcript level during cellular response to copper ion starvation during vegetative growth" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to copper ion starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0003197 ! altered RNA level during cellular response to copper ion starvation during vegetative growth created_by: midori creation_date: 2014-04-03T14:16:46Z [Term] id: FYPO:0003281 name: abnormal superoxide dismutase activity def: "A molecular function phenotype in which the observed rate of superoxide dismutase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-04-03T14:22:47Z [Term] id: FYPO:0003282 name: decreased superoxide dismutase activity def: "A molecular function phenotype in which the observed rate of superoxide dismutase activity is decreased." [PomBase:mah] synonym: "reduced superoxide dismutase activity" EXACT [PomBase:mah] is_a: FYPO:0003281 ! abnormal superoxide dismutase activity created_by: midori creation_date: 2014-04-03T14:22:55Z [Term] id: FYPO:0003283 name: abnormal copper import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of copper ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular copper import" EXACT [PomBase:al] synonym: "abnormal copper cation import" EXACT [PomBase:mah] synonym: "abnormal copper import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal copper import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal copper import into cell" EXACT [PomBase:mah] synonym: "abnormal copper ion import" EXACT [PomBase:mah] synonym: "abnormal copper ion import across plasma membrane" EXACT [GO:0098705] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2014-04-03T14:28:41Z [Term] id: FYPO:0003284 name: decreased copper import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of copper ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular copper import" EXACT [PomBase:al] synonym: "decreased copper cation import" EXACT [PomBase:mah] synonym: "decreased copper import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased copper import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased copper import into cell" EXACT [PomBase:mah] synonym: "decreased copper ion import" EXACT [PomBase:mah] synonym: "decreased copper ion import across plasma membrane" EXACT [GO:0098705] synonym: "reduced copper import" EXACT [PomBase:mah] is_a: FYPO:0003283 ! abnormal copper import created_by: midori creation_date: 2014-04-03T14:28:49Z [Term] id: FYPO:0003285 name: decreased alpha,alpha-trehalase activity during cellular response to nutrient def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during a cellular response to nutrient." [PomBase:mah] synonym: "decreased neutral trehalase activity during cellular response to nutrient" EXACT [PMID:9729425, PomBase:mah] synonym: "decreased trehalase activity during cellular response to nutrient" BROAD [GO:0004555, GO:0015927] synonym: "reduced alpha,alpha-trehalase activity during cellular response to nutrient" EXACT [PomBase:mah] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-04-03T14:46:28Z [Term] id: FYPO:0003286 name: decreased mitotic chromosome condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased chromosome condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitotic chromosome condensation" EXACT [PomBase:mah] is_a: FYPO:0000214 ! abnormal mitotic chromosome condensation is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2014-04-15T14:27:46Z [Term] id: FYPO:0003287 name: abnormal cell cycle arrest in meiotic interphase before premeiotic DNA replication def: "A cellular process phenotype in which progression through the meiotic cell cycle is arrested during the first meiotic interphase, before premeiotic DNA replication has taken place." [GO:0051328, PomBase:mah] synonym: "abnormal cell cycle arrest in meiotic interphase preceding premeiotic DNA replication" EXACT [PomBase:vw] synonym: "abnormal meiotic cell cycle arrest in interphase before premeiotic DNA replication" EXACT [PomBase:mah] is_a: FYPO:0002224 ! abnormally arrested meiotic cell cycle created_by: midori creation_date: 2014-04-15T15:44:58Z [Term] id: FYPO:0003289 name: abnormal protein localization to medial cortical node def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "abnormal protein localization to cortical medial dot" EXACT [PMID:9105045, PomBase:vw] synonym: "abnormal protein localization to cytokinetic nodes" RELATED [PMID:24127216] synonym: "abnormal protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to medial cortical nodes" EXACT [PomBase:mah] synonym: "abnormal protein recruitment to medial cortical node" RELATED [PomBase:vw] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2014-04-15T16:09:09Z [Term] id: FYPO:0003290 name: abnormal glycoprotein glycan structure def: "A phenotype in which the structure of the glycan moiety of a glycoprotein differs from wild type." [PMID:9125114, PomBase:mah] synonym: "abnormal glycoprotein oligosaccharide structure" RELATED [Pombase:vw] is_a: FYPO:0001985 ! abnormal phenotype relationship: output_of FYPO:0001910 ! abnormal protein glycosylation during vegetative growth created_by: midori creation_date: 2014-04-15T16:39:46Z [Term] id: FYPO:0003291 name: galactose absent from glycoprotein glycan def: "A phenotype in which the glycan moiety of a glycoprotein does not contain galactose residues. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages." [PMID:9125114, PomBase:mah] synonym: "alpha 1,2-linked galactose residues absent from glycoprotein" EXACT [PMID:9125114, PomBase:vw] synonym: "galactose absent from glycoprotein oligosaccharide" RELATED [PomBase:vw] is_a: FYPO:0003290 ! abnormal glycoprotein glycan structure created_by: midori creation_date: 2014-04-15T16:40:45Z [Term] id: FYPO:0003292 name: abnormal UDP-galactose transmembrane transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UDP-galactose transmembrane transport is abnormal." [PomBase:mah] synonym: "abnormal UDP-galactose transmembrane transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal UDP-galactose transmembrane transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2014-04-15T16:47:51Z [Term] id: FYPO:0003293 name: increased UDP-galactose transmembrane transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UDP-galactose transmembrane transport occurs to a greater extent than normal." [PomBase:mah] synonym: "increased UDP-galactose transmembrane transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased UDP-galactose transmembrane transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003292 ! abnormal UDP-galactose transmembrane transport created_by: midori creation_date: 2014-04-15T16:48:09Z [Term] id: FYPO:0003294 name: normal UDP-galactose transmembrane transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UDP-galactose transmembrane transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal UDP-galactose transmembrane transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal UDP-galactose transmembrane transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2014-04-15T16:50:17Z [Term] id: FYPO:0003295 name: normal growth on amitrole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amitrole." [PomBase:mah] synonym: "normal cell population growth in presence of amitrole" EXACT [PomBase:mah] synonym: "normal cell population growth on 3-amino-1,2,4-triazole" EXACT [CHEBI:40036, PomBase:mah] synonym: "normal cell population growth on 3-AT" EXACT [PomBase:mah] synonym: "normal cell population growth on 3AT" EXACT [PMID:23671279] synonym: "normal cell population growth on amitrole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to amitrole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on amitrole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-04-16T16:23:41Z [Term] id: FYPO:0003296 name: normal ribosome binding def: "A molecular function phenotype in which occurrence of ribosome binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-04-16T16:27:17Z [Term] id: FYPO:0003297 name: abolished ribosome binding def: "A molecular function phenotype in which ribosome binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "ribosome binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction created_by: midori creation_date: 2014-04-16T16:27:57Z [Term] id: FYPO:0003298 name: decreased protein autophosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophosphorylation of one or more specific proteins, or of specific protein sites, is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein autophosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein autophosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003019 ! abnormal protein autophosphorylation during vegetative growth created_by: midori creation_date: 2014-04-16T16:28:34Z [Term] id: FYPO:0003299 name: normal protein degradation via N-end rule pathway during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitin-dependent protein degradation via the N-end rule pathway is normal (i.e. indistinguishable from wild type). In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation." [GO:0071596, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein degradation via N-end rule pathway during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal ubiquitin-dependent protein breakdown via the N-end rule pathway during vegetative growth" EXACT [GO:0071596, PomBase:mah] synonym: "normal ubiquitin-dependent protein catabolic process via the N-end rule pathway during vegetative growth" EXACT [GO:0071596] synonym: "normal ubiquitin-dependent protein catabolism via the N-end rule pathway during vegetative growth" EXACT [GO:0071596, PomBase:mah] synonym: "normal ubiquitin-dependent protein degradation via the N-end rule pathway during vegetative growth" EXACT [GO:0071596, PomBase:mah] is_a: FYPO:0002799 ! normal protein degradation created_by: midori creation_date: 2014-04-16T16:37:32Z [Term] id: FYPO:0003300 name: decreased protein degradation via N-end rule pathway during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation via the N-end rule pathway is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein degradation via N-end rule pathway during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ubiquitin-dependent protein breakdown via the N-end rule pathway during vegetative growth" EXACT [GO:0071596] synonym: "decreased ubiquitin-dependent protein catabolic process via the N-end rule pathway during vegetative growth" EXACT [GO:0071596] synonym: "decreased ubiquitin-dependent protein catabolism via the N-end rule pathway during vegetative growth" EXACT [GO:0071596, PomBase:mah] synonym: "decreased ubiquitin-dependent protein degradation via the N-end rule pathway during vegetative growth" EXACT [GO:0071596, PomBase:mah] synonym: "reduced protein degradation via N-end rule pathway during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth is_a: FYPO:0002797 ! decreased protein degradation created_by: midori creation_date: 2014-04-16T16:41:59Z [Term] id: FYPO:0003301 name: delayed onset of protein degradation via N-end rule pathway during meiosis def: "A cellular process phenotype in which ubiquitin-dependent protein degradation via the N-end rule pathway begins later than normal during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein degradation via N-end rule pathway during meiotic nuclear division" EXACT [PomBase:mah] synonym: "delayed onset of ubiquitin-dependent protein breakdown via the N-end rule pathway during meiosis" EXACT [GO:0071596] synonym: "delayed onset of ubiquitin-dependent protein catabolic process via the N-end rule pathway during meiosis" EXACT [GO:0071596] synonym: "delayed onset of ubiquitin-dependent protein catabolism via the N-end rule pathway during meiosis" EXACT [GO:0071596, PomBase:mah] synonym: "delayed onset of ubiquitin-dependent protein degradation via the N-end rule pathway during meiosis" EXACT [GO:0071596, PomBase:mah] synonym: "delayed protein degradation via N-end rule pathway during meiosis" EXACT [PomBase:mah] is_a: FYPO:0006531 ! delayed onset of protein degradation during meiosis created_by: midori creation_date: 2014-04-16T16:44:49Z [Term] id: FYPO:0003302 name: nucleus mislocalized towards cell tip during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is located near one cell tip (instead of at the midpoint of the long axis of the cell) during interphase of the mitotic cell cycle." [PMID:9348288, PomBase:mah] synonym: "displaced interphase nucleus" RELATED [PomBase:vw] synonym: "displaced premitotic nucleus" RELATED [PomBase:vw] synonym: "interphase nucleus mislocalized to cell tip" EXACT [PomBase:vw] synonym: "nuclear displacement towards cell tip during mitotic interphase" EXACT [PomBase:vw] synonym: "nucleus displaced towards cell tip during mitotic interphase" EXACT [PomBase:vw] synonym: "nucleus mislocalised to cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "nucleus mislocalized towards cell end during mitotic interphase" EXACT [PomBase:mah] synonym: "nucleus mislocalized towards cell tip during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "nucleus mislocalized towards cell tip during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "off-centre interphase nucleus" EXACT [PomBase:vw] synonym: "off-centre premitotic nucleus" EXACT [PomBase:vw] is_a: FYPO:0002071 ! mislocalized nucleus during vegetative growth created_by: midori creation_date: 2014-04-23T11:11:11Z [Term] id: FYPO:0003303 name: mislocalized post-anaphase array def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the post-anaphase array of microtubules is present in an abnormal location." [PMID:9348288, PomBase:mah] synonym: "mislocalised post-anaphase array" EXACT [PomBase:mah] synonym: "mislocalized PAA" EXACT [PomBase:mah] synonym: "mislocalized post-anaphase array during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized post-anaphase array during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized post-anaphase microtubule array" EXACT [PomBase:mah] is_a: FYPO:0004316 ! abnormal post-anaphase array created_by: midori creation_date: 2014-04-23T11:29:00Z [Term] id: FYPO:0003304 name: abnormal mitotic spindle midzone assembly def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap, is abnormal." [GO:0051256, PomBase:mah] synonym: "abnormal mitotic spindle midzone assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spindle midzone assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle midzone assembly involved in mitosis" EXACT [GO:0051256] is_a: FYPO:0000177 ! abnormal mitotic spindle assembly created_by: midori creation_date: 2014-04-23T11:37:40Z [Term] id: FYPO:0003305 name: separate mitotic half spindles present def: "A spindle phenotype in which polar microtubules fail to interdigitate properly, and two partially or completely separated microtubule structures, usually V-shaped, each corresponding to one half of the spindle, are present." [PMID:9348288, PomBase:mah] synonym: "broken spindle interzone" RELATED [PMID:11694582] synonym: "broken spindle midzone" RELATED [PomBase:mah] synonym: "loss of interdigitation between mitotic half spindles" EXACT [PomBase:vw] synonym: "separate half spindles present during mitosis" EXACT [PomBase:mah] synonym: "separate half spindles present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "separate mitotic half spindles present during vegetative growth" EXACT [PomBase:mah] synonym: "spindle fraying" RELATED [PMID:9348288] is_a: FYPO:0000338 ! abnormal mitotic spindle relationship: output_of FYPO:0003304 ! abnormal mitotic spindle midzone assembly created_by: midori creation_date: 2014-04-23T11:42:54Z [Term] id: FYPO:0003306 name: decreased mitotic index def: "A cell population phenotype in which the mitotic index is lower than normal. The mitotic index is the proportion of the population undergoing mitosis at any given time." [PMID:11683392, PMID:22684255, PomBase:mah] synonym: "reduced mitotic index" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-04-23T14:26:21Z [Term] id: FYPO:0003307 name: increased mitotic index def: "A cell population phenotype in which the mitotic index is higher than normal. The mitotic index is the proportion of the population undergoing mitosis at any given time." [PMID:11683392, PMID:22684255, PomBase:mah] comment: Mitotic index is typically determined by microscopy, either by using tubulin immunofluorescence to detect spindles, or by using DAPI staining to detect DNA, where the presence of two nuclei but no septum is interpreted as anaphase. is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-04-23T14:26:27Z [Term] id: FYPO:0003308 name: normal protein localization to mitotic spindle pole body during interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during interphase of the cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle pole body during interphase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic SPB during interphase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle pole body during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole body during interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0002967 ! normal protein localization to mitotic spindle pole body created_by: midori creation_date: 2014-04-23T14:46:59Z [Term] id: FYPO:0003309 name: abnormal IMP cyclohydrolase activity def: "A molecular function phenotype in which the observed rate of IMP cyclohydrolase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-04-23T14:50:12Z [Term] id: FYPO:0003310 name: abolished IMP cyclohydrolase activity def: "A molecular function phenotype in which IMP cyclohydrolase activity is absent." [PomBase:mah] synonym: "IMP cyclohydrolase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003309 ! abnormal IMP cyclohydrolase activity created_by: midori creation_date: 2014-04-23T14:50:25Z [Term] id: FYPO:0003311 name: abnormal phosphoribosylaminoimidazolecarboxamide formyltransferase activity def: "A molecular function phenotype in which the observed rate of phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR formyltransferase) activity is abnormal." [PomBase:mah] synonym: "abnormal AICAR formyltransferase activity" EXACT [GO:0004643] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-04-23T14:50:45Z [Term] id: FYPO:0003312 name: abolished phosphoribosylaminoimidazolecarboxamide formyltransferase activity def: "A molecular function phenotype in which phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR formyltransferase) activity is absent." [PomBase:mah] synonym: "abolished AICAR formyltransferase activity" EXACT [GO:0004643] synonym: "phosphoribosylaminoimidazolecarboxamide formyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003311 ! abnormal phosphoribosylaminoimidazolecarboxamide formyltransferase activity created_by: midori creation_date: 2014-04-23T14:50:51Z [Term] id: FYPO:0003313 name: inviable after spore germination, without cell division, mononucleate cell with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and in which the nucleus does not divide. The cell does not divide, and eventually dies." [PomBase:mah] synonym: "inviable after spore germination, without cell division, elongated mononucleate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, mononucleate cell with elongated germ tube" EXACT [PomBase:mah] synonym: "inviable mononucleate germinated spore with elongated germ tube" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, mononucleate cell with elongated germ tube" EXACT [PomBase:mah] synonym: "mononucleate after spore germination with elongated germ tube" EXACT [PomBase:vw] is_a: FYPO:0002379 ! inviable after spore germination, without cell division, with elongated germ tube is_a: FYPO:0004255 ! inviable elongated mononucleate vegetative cell created_by: midori creation_date: 2014-04-23T14:56:10Z [Term] id: FYPO:0003314 name: activation of monopolar cell growth at new end def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth occurs at the new end of the cell, instead of at the old end, following cell division." [PomBase:mah] synonym: "abnormal initiation of growth from new end following cell division" EXACT [PomBase:mah] synonym: "activation of monopolar vegetative cell growth at new end" EXACT [PomBase:mah] is_a: FYPO:0001393 ! abnormal activation of monopolar cell growth created_by: midori creation_date: 2014-04-23T16:13:44Z [Term] id: FYPO:0003315 name: actin cables absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable actin cables." [PomBase:mah] synonym: "absent actin cables" EXACT [PomBase:mah] synonym: "actin cables absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cables absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "formin-nucleated actin cables absent from cell" EXACT [PomBase:mah] is_a: FYPO:0002435 ! abnormal actin cables created_by: midori creation_date: 2014-04-23T16:18:19Z [Term] id: FYPO:0003316 name: normal protein localization to growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the growing cell tip is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to growing cell tip" EXACT [PomBase:mah] synonym: "normal protein localization to growing cell end" EXACT [PomBase:mah] synonym: "normal protein localization to growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-04-23T16:20:28Z [Term] id: FYPO:0003317 name: decreased protein localization to growing cell tip, with protein distributed in plasma membrane or cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a growing cell tip is decreased, and the protein is also detected distributed throughout the plasma membrane and/or cell cortex." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to growing cell tip, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to growing cell end, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to growing cell tip, with protein distributed in cell cortex" NARROW [PomBase:mah] synonym: "decreased protein localization to growing cell tip, with protein distributed in cell membrane or cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to growing cell tip, with protein distributed in plasma membrane" NARROW [PomBase:mah] synonym: "decreased protein localization to growing cell tip, with protein distributed in plasma membrane or cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to growing cell tip, with protein distributed in plasma membrane or cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to growing cell tip, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] is_a: FYPO:0002871 ! decreased protein localization to growing cell tip created_by: midori creation_date: 2014-04-23T16:24:17Z [Term] id: FYPO:0003318 name: abolished galactose-specific flocculation during vegetative growth def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which galactose-specific flocculation does not occur. Galactose-specific flocculation is the non-sexual aggregation of cells, mediated via the binding of cell wall proteins on one cell to galactose residues on the other." [GO:0036349, PomBase:mah] synonym: "abolished cell-cell adhesion involved in galactose-specific flocculation during vegetative growth" EXACT [GO:0036349] synonym: "abolished galactose-specific flocculation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "galactose-specific flocculation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth is_a: FYPO:0005504 ! abolished galactose-specific flocculation created_by: midori creation_date: 2014-04-29T11:01:09Z [Term] id: FYPO:0003319 name: increased mannose-specific flocculation def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which mannose-specific flocculation is increased. Mannose-specific flocculation is the non-sexual aggregation of cells, mediated via the binding of cell wall proteins on one cell to mannose residues on the other, and when it is increased cells adhere to each other more strongly or to a greater extent than normal." [GO:0036350, PomBase:mah] synonym: "increased cell-cell adhesion involved in mannose-specific flocculation" EXACT [GO:0036350] synonym: "increased mannose-specific flocculation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mannose-specific flocculation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth created_by: midori creation_date: 2014-04-29T11:01:15Z [Term] id: FYPO:0003320 name: abnormal NADH dehydrogenase (ubiquinone) activity def: "A molecular function phenotype in which the observed rate of NADH dehydrogenase (ubiquinone) activity is abnormal." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'abnormal cellular respiration' (FYPO:0000078). is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-04-29T11:20:47Z [Term] id: FYPO:0003321 name: decreased NADH dehydrogenase (ubiquinone) activity def: "A molecular function phenotype in which the observed rate of NADH dehydrogenase (ubiquinone) activity is decreased." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'decreased cellular respiration' (FYPO:0000342). synonym: "reduced NADH dehydrogenase (ubiquinone) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003320 ! abnormal NADH dehydrogenase (ubiquinone) activity created_by: midori creation_date: 2014-04-29T11:20:55Z [Term] id: FYPO:0003322 name: abnormal succinate dehydrogenase (ubiquinone) activity def: "A molecular function phenotype in which the observed rate of succinate dehydrogenase (ubiquinone) activity is abnormal." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'abnormal cellular respiration' (FYPO:0000078). is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-04-29T11:21:16Z [Term] id: FYPO:0003323 name: abolished succinate dehydrogenase (ubiquinone) activity def: "A molecular function phenotype in which succinate dehydrogenase (ubiquinone) activity is absent." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'decreased cellular respiration' (FYPO:0000342). synonym: "succinate dehydrogenase (ubiquinone) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003322 ! abnormal succinate dehydrogenase (ubiquinone) activity created_by: midori creation_date: 2014-04-29T11:21:37Z [Term] id: FYPO:0003324 name: altered cytochrome absorption spectrum def: "A phenotype in which the spectrum of light absorption observed in whole cells or isolated mitochondria, and attributed to cytochromes present, differs from wild type." [PMID:22349564, PMID:8668131, PomBase:mah] synonym: "altered mitochondrial absorption spectrum" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-04-29T11:59:47Z [Term] id: FYPO:0003325 name: resistance to methotrexate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methotrexate than normal." [PomBase:mah] synonym: "resistance to methotrexate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to methotrexate during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to methotrexate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-04-29T13:18:48Z [Term] id: FYPO:0003326 name: normal interphase microtubule nucleation def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB)." [PMID:19001497, PomBase:mah] synonym: "normal interphase cytoplasmic microtubule nucleation" EXACT [PomBase:mah] synonym: "normal microtubule nucleation during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal microtubule nucleation during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal microtubule nucleation during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-04-29T13:48:16Z [Term] id: FYPO:0003327 name: curved interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are curved, i.e. follow a smooth bend rather than a straight line, during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "curved cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "curved interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "curved interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "curved interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003625 ! abnormal microtubule cytoskeleton morphology during mitotic interphase is_a: FYPO:0004862 ! curved microtubules is_a: FYPO:0006101 ! abnormal interphase microtubules created_by: midori creation_date: 2014-04-29T13:51:48Z [Term] id: FYPO:0003328 name: misoriented interphase microtubules def: "A microtubule organization phenotype observed in the vegetative growth phase of the life cycle in which the orientation of cytoplasmic microtubules within a cell is abnormal during interphase of the mitotic cell cycle. The normal orientation is parallel to the long axis of the cell." [PomBase:mah] synonym: "misoriented cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "misoriented interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "misoriented interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "misoriented interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006101 ! abnormal interphase microtubules created_by: midori creation_date: 2014-04-29T13:53:11Z [Term] id: FYPO:0003329 name: abolished protein localization to cell tip during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip does not occur during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cell end during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cell tip abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001585 ! abolished protein localization to cell tip during vegetative growth created_by: midori creation_date: 2014-04-29T13:58:27Z [Term] id: FYPO:0003330 name: normal protein localization to new mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the new mitotic spindle pole body is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal asymmetric protein localization to new mitotic spindle pole body" EXACT [GO:0061510] synonym: "normal protein localisation to new mitotic spindle pole body" EXACT [PomBase:mah] synonym: "normal protein localization to new mitotic SPB" EXACT [PomBase:mah] synonym: "normal protein localization to new mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to new spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-04-29T14:04:57Z [Term] id: FYPO:0003331 name: decreased protein kinase activity during mitotic interphase def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "reduced protein kinase activity during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2014-04-29T14:07:34Z [Term] id: FYPO:0003332 name: normal protein kinase activity during mitotic interphase def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] is_a: FYPO:0003075 ! normal protein kinase activity created_by: midori creation_date: 2014-04-29T14:08:34Z [Term] id: FYPO:0003333 name: inviable lemon-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell is inviable, and grows in the form of a lemon prior to cell death. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc." [http://mathworld.wolfram.com/Lemon.html, PomBase:mah] synonym: "inviable lemon-shaped cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable lemon-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable lemon-shaped vegetative cell" EXACT [PomBase:mah] synonym: "lethal; lemon-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0000224 ! lemon-shaped cell is_a: FYPO:0002451 ! inviable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000224 ! lemon-shaped cell created_by: midori creation_date: 2014-04-29T14:10:35Z [Term] id: FYPO:0003334 name: normal protein localization to septin ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to septin ring" EXACT [PomBase:mah] synonym: "normal protein localization to septin ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to septin ring during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-04-29T14:17:37Z [Term] id: FYPO:0003335 name: increased galactose-specific flocculation def: "A cell population phenotype that reflects increased occurrence of galactose-specific flocculation. Galactose-specific flocculation is the non-sexual aggregation of single cells, mediated by the binding of cell wall proteins on one cell to galactose residues on the other." [GO:0036349, PomBase:mah] synonym: "flocculating cells, galactose-specific" EXACT [PomBase:mah] is_a: FYPO:0000155 ! increased flocculation created_by: midori creation_date: 2014-04-29T14:33:45Z [Term] id: FYPO:0003336 name: increased duration of protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the actomyosin contractile ring for a longer time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "increased duration of protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "increased duration of protein localization to contractile ring" EXACT [PomBase:mah] synonym: "increased duration of protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "increased duration of protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "increased duration of protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "prolonged protein localization to actomyosin contractile ring" EXACT [PomBase:vw] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2014-05-07T14:53:08Z [Term] id: FYPO:0003337 name: increased protein localization to septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to septum" EXACT [PomBase:mah] synonym: "increased protein localization to cell septum" EXACT [PomBase:al] synonym: "increased protein localization to division septum" EXACT [GO:0000935, PomBase:mah] synonym: "increased protein localization to septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002718 ! abnormal protein localization to septum created_by: midori creation_date: 2014-05-07T14:55:56Z [Term] id: FYPO:0003338 name: abnormal actomyosin contractile ring morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actomyosin contractile ring is abnormal." [PomBase:mah] synonym: "abnormal actomyosin contractile ring morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring morphology" EXACT [PomBase:mah] synonym: "abnormal cytokinetic contractile ring morphology" EXACT [PomBase:vw] synonym: "abnormal mitotic contractile ring morphology" EXACT [PomBase:vw] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology during vegetative growth is_a: FYPO:0004736 ! abnormal actomyosin contractile ring created_by: midori creation_date: 2014-05-07T14:59:58Z [Term] id: FYPO:0003339 name: decreased rate of actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring assembly is decreased. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins." [PomBase:mah] synonym: "decreased rate of actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of contractile ring assembly" EXACT [PomBase:mah] synonym: "decreased rate of cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "decreased rate of mitotic contractile ring assembly" EXACT [PomBase:mah] synonym: "reduced rate of actomyosin contractile ring assembly" EXACT [PomBase:mah] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly created_by: midori creation_date: 2014-05-07T15:02:59Z [Term] id: FYPO:0003340 name: decreased re-entry into mitotic cell cycle during recovery from stationary phase def: "A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle is decreased when the cell is in a population that has been in stationary phase and is then placed in conditions that allow recovery." [PMID:9199286, PomBase:mah] synonym: "decreased re-entry into mitotic cell cycle following growth to stationary phase" EXACT [PomBase:al] synonym: "reduced re-entry into mitotic cell cycle during recovery from stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype created_by: midori creation_date: 2014-05-07T15:40:33Z [Term] id: FYPO:0003341 name: multinucleate def: "A physical cellular phenotype in which a cell contains more than one nucleus." [PomBase:mah] synonym: "multinucleate cells" EXACT [PomBase:al] synonym: "multiple nuclei" EXACT [PomBase:al] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2014-05-07T15:45:12Z [Term] id: FYPO:0003342 name: elongated multinucleate cell def: "A cell phenotype in which a cell contains more than one nucleus, is longer than normal, and has a greater length:diameter ratio than normal." [PomBase:mah] synonym: "long multinucleate cell" EXACT [PomBase:vw] is_a: FYPO:0003341 ! multinucleate is_a: FYPO:0006633 ! increased cell length created_by: midori creation_date: 2014-05-07T15:47:45Z [Term] id: FYPO:0003343 name: elongated multinucleate multiseptate cell, single septa between nuclei def: "A cell morphology phenotype in which a cell is elongated, has two or more nuclei and more than one septum, and the septa not grouped together, but are located so as to form separate compartments with a single nucleus in each." [PomBase:mah, PomBase:vw] is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell is_a: FYPO:0003342 ! elongated multinucleate cell created_by: midori creation_date: 2014-05-07T15:51:02Z [Term] id: FYPO:0003344 name: elongated multinucleate multiseptate cell, single septa between nuclei, during stationary phase def: "A cell morphology phenotype observed when a cell population is in stationary phase in which a cell is elongated, has two or more nuclei and more than one septum, and the septa not grouped together, but are located so as to form separate compartments with a single nucleus in each." [PomBase:mah, PomBase:vw] synonym: "elongated multinucleate multiseptate cell, single septa between nuclei during stationary phase" EXACT [PomBase:mah] synonym: "elongated multinucleate multiseptate cell, single septa between nuclei, during stationary phase during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003343 ! elongated multinucleate multiseptate cell, single septa between nuclei created_by: midori creation_date: 2014-05-07T15:52:21Z [Term] id: FYPO:0003345 name: abolished cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation does not occur; arrest normally occurs in G1 phase." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abolished cell cycle arrest in mitotic G1 phase during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "abolished cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "abolished mitotic cell cycle arrest in G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] synonym: "cell cycle arrest in mitotic G1 phase in response to nitrogen starvation abolished" EXACT [PomBase:mah] is_a: FYPO:0000710 ! abnormal mitotic cell cycle arrest in response to nitrogen starvation created_by: midori creation_date: 2014-05-07T15:56:55Z [Term] id: FYPO:0003346 name: abnormal meiotic recombination at silent mating-type cassette def: "A cellular process phenotype in which reciprocal meiotic recombination is abnormal at the silent mating-type cassettes. Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes." [GO:0007131, PomBase:mah] synonym: "abnormal meiotic DNA recombination at silent mating-type cassette" EXACT [PomBase:mah] synonym: "abnormal meiotic recombination at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "abnormal reciprocal meiotic recombination at silent mating-type cassette" EXACT [PomBase:mah] synonym: "abnormal recombination at silent mating-type cassette" BROAD [PomBase:mah] synonym: "DNA recombination defects, meiotic, at silent mating-type cassette" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2014-05-07T16:08:59Z [Term] id: FYPO:0003347 name: altered substrate specificity def: "A molecular function phenotype in which the substrate specificity of a catalytic activity differs from wild type." [PMID:23091597, PomBase:mah] synonym: "abnormal catalytic activity, altered substrate specificity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-05-07T16:19:46Z [Term] id: FYPO:0003348 name: altered substrate specificity, glutathione synthetase to homoglutathione synthetase activity def: "A molecular function phenotype in which the substrate specificity of a gene product that executes glutathione synthetase activity in wild type is altered such that the gene product executes homoglutathione synthetase activity." [PMID:23091597, PomBase:mah] synonym: "abnormal catalytic activity, altered substrate specificity, glutathione synthetase to homoglutathione synthetase activity" EXACT [PomBase:mah] is_a: FYPO:0003347 ! altered substrate specificity created_by: midori creation_date: 2014-05-07T16:24:09Z [Term] id: FYPO:0003349 name: normal protein localization to mitotic spindle midzone during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase B is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart." [GO:0000092, GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle midzone during anaphase B" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle midzone during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to spindle midzone during anaphase B during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004692 ! normal protein localization to mitotic spindle midzone created_by: midori creation_date: 2014-05-07T16:41:21Z [Term] id: FYPO:0003350 name: abolished protein localization to mitotic spindle midzone during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase B does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart." [GO:0000092, GO:1902967, GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle midzone during mitotic anaphase B" EXACT [PomBase:mah] synonym: "protein absent from mitotic spindle midzone during anaphase B" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle midzone abolished during anaphase B" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle midzone abolished during anaphase B" EXACT [PomBase:mah] synonym: "protein localization to spindle midzone abolished during anaphase B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003484 ! abolished protein localization to mitotic spindle midzone created_by: midori creation_date: 2014-05-07T16:44:01Z [Term] id: FYPO:0003351 name: increased duration of protein localization to kinetochore during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the kinetochore of a chromosome for a longer time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] synonym: "prolonged protein localization to kinetochore during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001268 ! abnormal protein localization to kinetochore during vegetative growth created_by: midori creation_date: 2014-05-07T16:46:42Z [Term] id: FYPO:0003352 name: decreased DNA double-strand break formation at mating-type locus def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which DNA double-strand break formation occurs to a lower extent than normal during gene conversion at the mating-type locus." [PomBase:mah] synonym: "decreased DNA double-strand break formation at mating-type locus during gene conversion" EXACT [PomBase:mah] synonym: "decreased DNA double-strand break formation at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased DNA double-strand break formation at mating-type locus during vegetative growth" EXACT [PomBase:mah] synonym: "decreased DNA double-strand break formation during gene conversion at mating-type locus" EXACT [PomBase:mah] synonym: "decreased DSB formation at mat1" EXACT [PomBase:al] synonym: "decreased DSB formation at mating-type locus" EXACT [PomBase:mah] synonym: "decreased DSB formation proximal to mat1" EXACT [PomBase:al] synonym: "decreased gene conversion at mating-type locus, DNA double-strand break formation" EXACT [GO:0000728] synonym: "reduced DNA double-strand break formation at mating-type locus" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth relationship: has_output FYPO:0000470 ! decreased mating type switching created_by: midori creation_date: 2014-05-07T17:25:17Z [Term] id: FYPO:0003353 name: normal DNA double-strand break formation at mating-type locus def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which DNA double-strand break formation is normal (i.e. indistinguishable from wild type) during gene conversion at the mating-type locus." [PomBase:mah] synonym: "normal DNA double-strand break formation at mating-type locus during gene conversion" EXACT [PomBase:mah] synonym: "normal DNA double-strand break formation at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA double-strand break formation at mating-type locus during vegetative growth" EXACT [PomBase:mah] synonym: "normal DNA double-strand break formation during gene conversion at mating-type locus" EXACT [PomBase:mah] synonym: "normal DSB formation at mat1" EXACT [PomBase:al] synonym: "normal DSB formation at mating-type locus" EXACT [PomBase:mah] synonym: "normal DSB formation proximal to mat1" EXACT [PomBase:al] synonym: "normal gene conversion at mating-type locus, DNA double-strand break formation" EXACT [GO:0000728] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-05-07T17:29:08Z [Term] id: FYPO:0003354 name: decreased galactose level in glycoprotein glycan def: "A phenotype in which the glycan moiety of a glycoprotein contains a lower amount of galactose residues than normal. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages." [PMID:8782411, PomBase:mah] synonym: "decreased galactose level in glycoprotein oligosaccharide" RELATED [PomBase:vw] synonym: "decreased level of alpha 1,2-linked galactose residues in glycoprotein glycan" EXACT [PomBase:mah] synonym: "decreased protein glycan galactosylation" RELATED [PMID:8782411, PomBase:al] synonym: "reduced galactose level in glycoprotein glycan" EXACT [PomBase:mah] is_a: FYPO:0003290 ! abnormal glycoprotein glycan structure created_by: midori creation_date: 2014-05-12T14:28:42Z [Term] id: FYPO:0003355 name: growth auxotrophic for sulfur-containing amino acid def: "Auxotrophy in which a cell is unable to synthesize sulfur-containing amino acids, and therefore requires one or more sulfur-containing amino acids (e.g. cysteine or methionine) in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for sulfur-containing amino acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for sulfur-containing amino acid during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for sulphur-containing amino acid" EXACT [PomBase:mah] synonym: "sulfur-containing amino acid auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2014-05-12T15:24:39Z [Term] id: FYPO:0003356 name: sensitive to papuamide B during mating def: "A phenotype in which cells show increased sensitivity to papuamide B during mating. Cells stop growing (and may die) at a concentration of papuamide B that allows wild type cells to grow." [PMID:24514900, PomBase:mah] synonym: "sensitive to papuamide B during conjugation with cellular fusion" EXACT [GO:0000747] synonym: "sensitivity to chemicals interfering with lipids during mating" BROAD [PMID:24514900] is_a: FYPO:0002683 ! increased sensitivity to chemical created_by: midori creation_date: 2014-05-12T15:40:53Z [Term] id: FYPO:0003357 name: sensitive to filipin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to filipin. Cells stop growing (and may die) at a concentration of filipin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to filipin" EXACT [PomBase:mah] synonym: "sensitive to filipin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to filipin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitivity to chemicals interfering with lipids" BROAD [PMID:24514900] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-05-12T15:46:17Z [Term] id: FYPO:0003358 name: sensitive to miconazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to miconazole. Cells stop growing (and may die) at a concentration of miconazole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to miconazole" EXACT [PomBase:mah] synonym: "sensitive to miconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to miconazole during vegetative growth" EXACT [PomBase:mah] synonym: "sensitivity to chemicals interfering with lipids" BROAD [PMID:24514900] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-05-12T15:47:17Z [Term] id: FYPO:0003359 name: sensitive to myriocin during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to myriocin. Cells stop growing (and may die) at a concentration of myriocin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to myriocin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to myriocin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitivity to chemicals interfering with lipids during vegetative growth" BROAD [PMID:24514900] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-05-12T15:48:32Z [Term] id: FYPO:0003360 name: abolished superoxide dismutase activity def: "A molecular function phenotype in which superoxide dismutase activity is absent." [PomBase:mah] synonym: "superoxide dismutase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003281 ! abnormal superoxide dismutase activity created_by: midori creation_date: 2014-05-29T15:25:07Z [Term] id: FYPO:0003361 name: normal superoxide dismutase activity def: "A molecular function phenotype in which the observed rate of superoxide dismutase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-05-29T15:31:09Z [Term] id: FYPO:0003362 name: normal protein acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein acetylation is normal (i.e. indistinguishable from wild type). Protein acetylation is the addition of an acetyl group to a protein amino acid." [GO:0006473, PomBase:mah] synonym: "normal protein acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2014-05-29T15:33:47Z [Term] id: FYPO:0003363 name: abolished cytogamy def: "A cellular process phenotype in which cytogamy does not occur. Cytogamy is the process that creates a single cell from two cells of complementary mating types." [GO:0000755, PomBase:mah] synonym: "conjugation without cellular fusion during mating" RELATED [PomBase:al] synonym: "cytogamy abolished" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2014-05-29T15:48:02Z [Term] id: FYPO:0003364 name: mislocalized nucleus during mating def: "A physical cellular phenotype in which a cell has a nucleus in an abnormal location during mating. The normal location of a single nucleus is at the midpoint of the long axis of the cell during vegetative growth, and during mating, the nucleus migrates towards the mating projection." [PMID:7791776, PomBase:al, PomBase:mah] synonym: "abnormal nucleus location during mating" EXACT [PomBase:mah] synonym: "abnormal nucleus position during mating" EXACT [PomBase:mah] synonym: "displaced nucleus during mating" EXACT [PomBase:vw] synonym: "mislocalised nucleus during mating" EXACT [PomBase:mah] synonym: "mislocalized nucleus during conjugation with cellular fusion" EXACT [GO:0000747] synonym: "misplaced nuclei during mating" EXACT [PomBase:vw] synonym: "misplaced nucleus during mating" EXACT [PomBase:vw] synonym: "nuclear displacement during mating" EXACT [PomBase:vw] is_a: FYPO:0002069 ! mislocalized nucleus created_by: midori creation_date: 2014-05-29T15:50:36Z [Term] id: FYPO:0003365 name: abnormal pyridoxine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pyridoxine into the cell is abnormal." [PomBase:mah] synonym: "abnormal pyridoxine import across plasma membrane" EXACT [GO:1903075] synonym: "abnormal pyridoxine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal pyridoxine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal pyridoxine import into cell" EXACT [PomBase:al] synonym: "abnormal pyridoxine uptake" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2014-05-29T16:04:35Z [Term] id: FYPO:0003366 name: decreased pyridoxine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pyridoxine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased pyridoxine import across plasma membrane" EXACT [GO:1903075] synonym: "decreased pyridoxine import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased pyridoxine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pyridoxine import into cell" EXACT [PomBase:al] synonym: "decreased pyridoxine uptake" EXACT [PomBase:mah] synonym: "reduced pyridoxine import" EXACT [PomBase:mah] is_a: FYPO:0003365 ! abnormal pyridoxine import created_by: midori creation_date: 2014-05-29T16:04:54Z [Term] id: FYPO:0003367 name: growth auxotrophic for pyridoxine def: "Auxotrophy in which a cell is unable to synthesize pyridoxine, and therefore requires pyridoxine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for pyridoxine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for pyridoxine during vegetative growth" EXACT [PomBase:mah] synonym: "pyridoxine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2014-05-29T16:07:39Z [Term] id: FYPO:0003368 name: resistance to sodium fluoride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium fluoride than normal." [PomBase:mah] synonym: "resistance to fluoride" BROAD [PomBase:mah] synonym: "resistance to NaF" EXACT [PomBase:mah] synonym: "resistance to sodium fluoride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to sodium fluoride during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to sodium fluoride" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-05-29T16:09:58Z [Term] id: FYPO:0003369 name: sensitive to sodium fluoride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium fluoride. Cells stop growing (and may die) at a concentration of sodium fluoride that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium fluoride" EXACT [PomBase:mah] synonym: "sensitive to fluoride" BROAD [PomBase:mah] synonym: "sensitive to NaF" EXACT [PomBase:mah] synonym: "sensitive to sodium fluoride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium fluoride during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2014-05-29T16:12:14Z [Term] id: FYPO:0003370 name: normal growth on sodium fluoride def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium fluoride." [PomBase:mah] synonym: "normal cell population growth in presence of sodium fluoride" EXACT [PomBase:mah] synonym: "normal cell population growth on sodium fluoride" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to sodium fluoride" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on NaF" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on sodium fluoride" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-05-29T16:14:04Z [Term] id: FYPO:0003371 name: abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is abolished, and the protein is present in the cytoplasm instead." [PMID:18256290, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to actomyosin contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:al] synonym: "abolished protein localization to cytokinetic contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:vw] synonym: "abolished protein localization to mitotic contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:vw] synonym: "abolished protein recruitment to actomyosin contractile ring, with protein mislocalized to cytoplasm" RELATED [PomBase:vw] synonym: "protein localization to actomyosin contractile ring abolished, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0002561 ! abolished protein localization to actomyosin contractile ring created_by: midori creation_date: 2014-05-29T16:16:00Z [Term] id: FYPO:0003372 name: RNA absent from cell during meiosis def: "A cell phenotype in which the amount of RNA measured in a cell is too low to detect during one or both meiotic nuclear divisions. Total RNA or a specific RNA may be affected." [PomBase:mah] synonym: "RNA absent from cell during meiotic nuclear division" EXACT [GO:0140013] synonym: "transcripts absent from cell during meiosis" EXACT [PomBase:vw] synonym: "undetectable cellular RNA level during meiosis" EXACT [PomBase:mah] is_a: FYPO:0006975 ! RNA absent from cell during meiotic cell cycle created_by: midori creation_date: 2014-05-29T16:34:44Z [Term] id: FYPO:0003374 name: normal cellular coenzyme Q10 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular coenzyme Q10 accumulation" RELATED [PomBase:mah] synonym: "normal cellular coenzyme Q10 level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular coenzyme Q10 level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2014-06-02T13:49:46Z [Term] id: FYPO:0003375 name: normal ubiquinone binding def: "A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal coenzyme Q binding" EXACT [GO:0048039] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-06-02T13:51:29Z [Term] id: FYPO:0003376 name: resistance to nitrogen starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to nitrogen starvation. Cells go on to grow and divide to a greater extent than wild type following nitrogen starvation." [PomBase:al, PomBase:mah] comment: Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation, but this term does not refer to such prolonged starvation. Use this term if you have assayed growth of cells exposed to nitrogen starvation in culture. If you have assayed the response to nitrogen starvation at the subcellular or molecular level, consider annotating to 'abnormal cellular response to nitrogen starvation' (FYPO:0000152). synonym: "increased cell population growth during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased growth during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "resistance to nitrogen depletion" EXACT [PomBase:vw] synonym: "resistance to nitrogen deprivation" EXACT [PomBase:vw] synonym: "resistance to nitrogen starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to nitrogen starvation during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2014-06-02T13:56:34Z [Term] id: FYPO:0003377 name: decreased RNA level during cellular response to nitrosative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to nitrosative stress is lower than normal. Total RNA or a specific RNA may be affected. Nitrosative stress often results from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions." [GO:0071500, PMID:20204527, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. NO levels can be increased experimentally by adding sodium nitroprusside to growth media. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to nitrosative stress" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to nitrosative stress" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to nitrosative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to nitrosative stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to nitrosative stress" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to nitrosative stress" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-06-02T14:05:02Z [Term] id: FYPO:0003378 name: abolished meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division, in which homologous chromosomes are normally paired and segregated from each other, does not occur." [GO:0007127, PomBase:mah] synonym: "abolished first meiotic nuclear division" EXACT [PomBase:al] synonym: "absent meiosis I" EXACT [PomBase:mah] synonym: "meiosis I abolished" EXACT [PomBase:mah] synonym: "meiosis I: absent" EXACT [PomBase:mah] is_a: FYPO:0000474 ! abolished meiosis is_a: FYPO:0003603 ! abnormal meiosis I created_by: midori creation_date: 2014-06-02T14:29:46Z [Term] id: FYPO:0003379 name: abolished meiosis II def: "A cellular process phenotype in which the second meiotic nuclear division, in which two chromatids in each chromosome are normally separated, does not occur." [GO:0007135, PomBase:mah] synonym: "abolished second meiotic nuclear division" EXACT [PomBase:al] synonym: "absent meiosis II" EXACT [PomBase:mah] synonym: "meiosis II abolished" EXACT [PomBase:mah] synonym: "meiosis II: absent" EXACT [PomBase:mah] is_a: FYPO:0000474 ! abolished meiosis is_a: FYPO:0006526 ! abnormal meiosis II created_by: midori creation_date: 2014-06-02T14:31:32Z [Term] id: FYPO:0003380 name: decreased frequency of meiosis I def: "A cell population phenotype in which the frequency of occurrence of the first meiotic nuclear division, in which homologous chromosomes are normally paired and segregated from each other, is decreased." [PomBase:mah] synonym: "decreased frequency of first meiotic nuclear division" EXACT [PomBase:al] synonym: "decreased meiosis I" EXACT [PomBase:mah] synonym: "meiosis I: decreased frequency" EXACT [PomBase:mah] synonym: "reduced frequency of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0000476 ! decreased frequency of meiosis created_by: midori creation_date: 2014-06-02T14:32:49Z [Term] id: FYPO:0003381 name: increased cellular glycerol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glycerol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular glycerol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased glycerol accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-06-02T15:27:01Z [Term] id: FYPO:0003382 name: increased cellular acetate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of acetate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased acetate accumulation" RELATED [PomBase:al] synonym: "increased cellular acetate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular acetate level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-06-02T15:28:29Z [Term] id: FYPO:0003383 name: resistance to tert-butyl hydroperoxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tert-butyl hydroperoxide (TBHP or t-BOOH) than normal." [PomBase:mah] synonym: "resistance to 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:64090] synonym: "resistance to t-BOOH" EXACT [PomBase:al, PomBase:mah] synonym: "resistance to TBHP" EXACT [CHEBI:64090, PomBase:al] synonym: "resistance to tert-butyl hydroperoxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tert-butyl hydroperoxide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tert-butyl hydroperoxide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-06-02T15:29:51Z [Term] id: FYPO:0003384 name: sensitive to chromium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chromium ions. Cells stop growing (and may die) at a concentration of chromium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to chromium" EXACT [PomBase:mah] synonym: "sensitive to chromium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to chromium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to chromium ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-06-02T15:36:35Z [Term] id: FYPO:0003385 name: increased cellular cadmium level during cellular response to cadmium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cadmium ions measured in a cell is higher than normal during a cellular response to cadmium ion." [PomBase:mah] synonym: "increased cadmium accumulation during cellular response to cadmium" RELATED [PomBase:al] synonym: "increased cellular cadmium accumulation during cellular response to cadmium" RELATED [PomBase:mah] synonym: "increased cellular cadmium ion level during cellular response to cadmium" EXACT [PomBase:mah] synonym: "increased cellular cadmium level during cellular response to cadmium" EXACT [PomBase:mah] synonym: "increased cellular cadmium level during cellular response to cadmium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular cadmium level during cellular response to cadmium during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-06-02T15:40:07Z [Term] id: FYPO:0003386 name: increased superoxide dismutase activity def: "A molecular function phenotype in which the observed rate of superoxide dismutase activity is increased." [PomBase:mah] is_a: FYPO:0003281 ! abnormal superoxide dismutase activity created_by: midori creation_date: 2014-06-02T15:42:15Z [Term] id: FYPO:0003387 name: decreased catalase activity def: "A molecular function phenotype in which the observed rate of catalase activity is decreased." [PomBase:mah] synonym: "reduced catalase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001104 ! abnormal catalase activity created_by: midori creation_date: 2014-06-02T15:42:47Z [Term] id: FYPO:0003388 name: decreased biotin import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased biotin import across plasma membrane" EXACT [GO:1905135] synonym: "decreased biotin import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased biotin import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased biotin import into cell" EXACT [PomBase:al] synonym: "decreased biotin uptake" EXACT [PomBase:mah] synonym: "reduced biotin import" EXACT [PomBase:mah] is_a: FYPO:0001744 ! abnormal biotin import created_by: midori creation_date: 2014-06-02T15:44:42Z [Term] id: FYPO:0003389 name: viable elongated vegetative cell with swollen medial region def: "A cell morphology phenotype in which a vegetative cell is viable, is elongated, has a larger diameter than normal near the equator (but not at the ends), and has an overall volume greater than normal." [PMID:24554432, PomBase:mah, PomBase:vw] synonym: "medial bulge formation phenotype" EXACT [PMID:24554432] synonym: "viable elongated vegetative cell with swollen medial region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable elongated vegetative cell with swollen medial region during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell is_a: FYPO:0002402 ! viable swollen vegetative cell with abnormal cell shape is_a: FYPO:0002479 ! viable swollen elongated vegetative cell created_by: midori creation_date: 2014-06-02T15:49:47Z [Term] id: FYPO:0003390 name: protein mislocalized to medial cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the medial cortex is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the medial cortex in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to medial cortex during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalised to medial cortex during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to medial cortex during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2014-06-02T16:00:13Z [Term] id: FYPO:0003391 name: abnormal ubiquinone binding def: "A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with ubiquinone that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal coenzyme Q binding" EXACT [GO:0048039] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-06-03T11:43:10Z [Term] id: FYPO:0003392 name: decreased ubiquinone binding def: "A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased coenzyme Q binding" EXACT [GO:0048039] synonym: "reduced ubiquinone binding" EXACT [PomBase:mah] is_a: FYPO:0003391 ! abnormal ubiquinone binding created_by: midori creation_date: 2014-06-03T11:43:17Z [Term] id: FYPO:0003393 name: abnormal respiratory electron transport def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which electron transport involved in cellular respiration is abnormal." [PomBase:mah] synonym: "abnormal respiratory electron transport chain" EXACT [GO:0022904] synonym: "abnormal respiratory electron transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal respiratory electron transport process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2014-06-03T11:54:26Z [Term] id: FYPO:0003394 name: decreased mitochondrial electron transport, NADH to ubiquinone def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from NADH to ubiquinone is decreased." [GO:0006120, PomBase:mah] synonym: "decreased mitochondrial electron transport, NADH to ubiquinone, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial electron transport, NADH to ubiquinone, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased NADH cytochrome c oxidoreductase" RELATED [PMID:8668131] synonym: "decreased NADH dehydrogenase (quinone) activity and ubiquinol-cytochrome-c reductase activity" RELATED [PMID:8668131, PomBase:vw] synonym: "reduced mitochondrial electron transport, NADH to ubiquinone" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-06-03T11:57:25Z [Term] id: FYPO:0003395 name: abolished mitochondrial electron transport, succinate to ubiquinone def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from succinate to ubiquinone, mediated by complex II, does not occur." [GO:0006121, PomBase:mah] synonym: "abolished mitochondrial electron transport, succinate to ubiquinone, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitochondrial electron transport, succinate to ubiquinone, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished succinate cytochrome c oxidoreductase" RELATED [PMID:8668131] synonym: "abolished succinate dehydrogenase (ubiquinone) activity and ubiquinol-cytochrome-c reductase activity" RELATED [PMID:8668131, PomBase:vw] synonym: "mitochondrial electron transport, succinate to ubiquinone, abolished" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-06-03T12:02:05Z [Term] id: FYPO:0003396 name: resistance to ricinoleic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ricinoleic acid than normal." [PomBase:mah] synonym: "resistance to RA" BROAD [PomBase:al] synonym: "resistance to ricinoleic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to ricinoleic acid during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to ricinoleic acid" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-06-03T12:29:08Z [Term] id: FYPO:0003397 name: decreased 35S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the 35S rRNA primary transcript measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 35S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "decreased 35S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased 35S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased 35S rRNA precursor transcript level" EXACT [PomBase:vw] synonym: "decreased 35S rRNA primary transcript level" EXACT [PomBase:mah, SO:0000325] synonym: "reduced 35S rRNA precursor level" EXACT [PomBase:mah] is_a: FYPO:0003601 ! decreased rRNA precursor level created_by: midori creation_date: 2014-06-03T13:28:48Z [Term] id: FYPO:0003398 name: decreased 32S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 32S rRNA precursor measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 32S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "decreased 32S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased 32S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased 32S rRNA precursor transcript level" EXACT [PomBase:vw] synonym: "reduced 32S rRNA precursor level" EXACT [PomBase:mah] is_a: FYPO:0003601 ! decreased rRNA precursor level created_by: midori creation_date: 2014-06-03T13:29:06Z [Term] id: FYPO:0003399 name: normal 27S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 27S ribosomal RNA precursor measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 27S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "normal 27S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal 27S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "normal 27S rRNA precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2014-06-03T13:34:04Z [Term] id: FYPO:0003400 name: normal 20S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 20S ribosomal RNA precursor measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 20S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "normal 20S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal 20S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "normal 20S rRNA precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2014-06-03T13:36:16Z [Term] id: FYPO:0003401 name: obsolete elongated cell during cellular response to osmotic stress def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated during a cellular response to osmotic stress." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated cell during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated cell during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "elongated in response to osmotic stress" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2014-06-03T14:18:47Z [Term] id: FYPO:0003402 name: abnormal mitotic cell cycle regulation during cellular response to osmotic stress def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to osmotic stress is abnormal." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to osmotic stress during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-06-03T14:19:45Z [Term] id: FYPO:0003403 name: abnormal glyoxalase III activity def: "A molecular function phenotype in which the observed rate of glyoxalase III activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-06-03T14:24:07Z [Term] id: FYPO:0003404 name: abolished glyoxalase III activity def: "A molecular function phenotype in which glyoxalase III activity is absent." [PomBase:mah] synonym: "glyoxalase III activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003403 ! abnormal glyoxalase III activity created_by: midori creation_date: 2014-06-03T14:24:17Z [Term] id: FYPO:0003405 name: decreased glyoxalase III activity def: "A molecular function phenotype in which the observed rate of glyoxalase III activity is decreased." [PomBase:mah] synonym: "reduced glyoxalase III activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003403 ! abnormal glyoxalase III activity created_by: midori creation_date: 2014-06-03T14:24:36Z [Term] id: FYPO:0003406 name: resistance to methylglyoxal def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methylglyoxal than normal." [PomBase:mah] synonym: "resistance to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to methylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to MG" BROAD [PomBase:al] synonym: "resistant to methylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-06-03T14:40:47Z [Term] id: FYPO:0003407 name: resistance to glyoxal def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of glyoxal than normal." [PomBase:mah] synonym: "resistance to glyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to glyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to GO" BROAD [PomBase:al] synonym: "resistant to glyoxal" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-06-03T14:41:33Z [Term] id: FYPO:0003408 name: sensitive to methylglyoxal def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methylglyoxal. Cells stop growing (and may die) at a concentration of methylglyoxal that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to methylglyoxal" EXACT [PomBase:mah] synonym: "sensitive to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to methylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to MG" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-06-03T14:42:12Z [Term] id: FYPO:0003409 name: abnormal CENP-A containing chromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) is abnormal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions." [GO:0034080, PMID:24710126, PomBase:mah, PomBase:vw] synonym: "abnormal CenH3-containing nucleosome assembly" RELATED [GO:0034080] synonym: "abnormal CENP-A containing nucleosome assembly" RELATED [] synonym: "abnormal CENP-A containing nucleosome assembly at centromere" EXACT [GO:0034080] synonym: "abnormal CENP-A containing nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal CENP-A containing nucleosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal CENP-A deposition" RELATED [GO:0034080] synonym: "abnormal CENP-A loading" RELATED [GO:0034080] synonym: "abnormal centromere-specific histone exchange" EXACT [GO:0034080] synonym: "abnormal centromere-specific nucleosome assembly" EXACT [GO:0034080] synonym: "abnormal centromeric DNA replication-independent nucleosome assembly" EXACT [GO:0034080] synonym: "abnormal DNA replication-independent nucleosome assembly at centromere" EXACT [GO:0034080] is_a: FYPO:0004308 ! abnormal CENP-A containing chromatin organization created_by: midori creation_date: 2014-06-03T15:37:34Z [Term] id: FYPO:0003410 name: increased spatial extent of CENP-A containing chromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a larger portion of the centromeric region of the chromosome than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions." [GO:0034080, PMID:24710126, PomBase:mah, PomBase:vw] synonym: "CENP-A containing nucleosome spreading" RELATED [PomBase:vw] synonym: "increased extent of CENP-A containing nucleosome" RELATED [PomBase:vw] synonym: "increased spatial extent of CenH3-containing nucleosome assembly at centromere" RELATED [GO:0034080] synonym: "increased spatial extent of CENP-A containing nucleosome assembly" RELATED [] synonym: "increased spatial extent of CENP-A containing nucleosome assembly at centromere" EXACT [GO:0034080] synonym: "increased spatial extent of CENP-A containing nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spatial extent of CENP-A containing nucleosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased spatial extent of CENP-A deposition" RELATED [GO:0034080] synonym: "increased spatial extent of CENP-A loading" RELATED [GO:0034080] synonym: "increased spatial extent of centromere-specific histone exchange" EXACT [GO:0034080] synonym: "increased spatial extent of centromere-specific nucleosome assembly" EXACT [GO:0034080] synonym: "increased spatial extent of centromeric DNA replication-independent nucleosome assembly" EXACT [GO:0034080] synonym: "increased spatial extent of DNA replication-independent nucleosome assembly at centromere" EXACT [GO:0034080] is_a: FYPO:0003409 ! abnormal CENP-A containing chromatin assembly created_by: midori creation_date: 2014-06-03T15:41:14Z [Term] id: FYPO:0003411 name: decreased chromatin silencing at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere inner repeat regions is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased chromatin silencing at centromere imr" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromeric inner repeat region" EXACT [PomBase:mah] synonym: "decreased heterochromatin silencing at centromere inner repeat" EXACT [PomBase:mah] synonym: "reduced chromatin silencing at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0002834 ! decreased chromatin silencing at centromere created_by: midori creation_date: 2014-06-03T15:53:45Z [Term] id: FYPO:0003412 name: decreased chromatin silencing at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "decreased heterochromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "reduced chromatin silencing at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0002346 ! abnormal chromatin silencing at centromere outer repeat is_a: FYPO:0002834 ! decreased chromatin silencing at centromere created_by: midori creation_date: 2014-06-03T15:54:43Z [Term] id: FYPO:0003413 name: inviable branched, elongated, multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, forms one or more branches near a septum, is elongated, and has more than one septum." [PMID:18256290, PomBase:mah] synonym: "inviable branched, elongated, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, elongated, multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable branched, long, multiseptate cell" EXACT [PomBase:vw] synonym: "lethal; branched, elongated, multiseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000134 ! branched, elongated, multiseptate cell is_a: FYPO:0001494 ! inviable elongated multiseptate vegetative cell is_a: FYPO:0002462 ! inviable branched, elongated vegetative cell created_by: midori creation_date: 2014-06-05T16:14:54Z [Term] id: FYPO:0003414 name: normal protein localization to septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to septum" EXACT [PomBase:mah] synonym: "normal protein localization to cell septum" EXACT [PomBase:al] synonym: "normal protein localization to division septum" EXACT [GO:0000935, PomBase:mah] synonym: "normal protein localization to septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-06-05T16:22:12Z [Term] id: FYPO:0003415 name: increased histone H4 acetylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a greater extent than normal at the central core of centromeric regions." [PomBase:mah] synonym: "increased histone H4 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4 acetylation at centromeric central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth created_by: midori creation_date: 2014-06-05T16:37:03Z [Term] id: FYPO:0003416 name: cytoplasmic vesicles present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic membrane-bounded vesicles than normal." [PomBase:mah] comment: This term can be used when the vesicles observed may be endocytic or exocytic vesicles. synonym: "additional cytoplasmic vesicles present during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic vesicles present in greater numbers" EXACT [PomBase:mah] synonym: "cytoplasmic vesicles present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic vesicles present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "extra cytoplasmic vesicles during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2014-06-11T11:58:49Z [Term] id: FYPO:0003417 name: increased microtubule dwell time at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule plus ends remain in contact with the cell cortex at cell tips for a longer time than normal." [PMID:24530531, PomBase:mah] synonym: "increased microtubule dwell time at cell end" EXACT [PomBase:mah] synonym: "increased microtubule dwell time at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased microtubule dwell time at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "increased microtubule plus end dwell time at cell tip" EXACT [PMID:24530531] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2014-06-11T12:05:54Z [Term] id: FYPO:0003418 name: abolished malate dehydrogenase (decarboxylating) (NAD+) activity def: "A molecular function phenotype in which malate dehydrogenase (decarboxylating) (NAD+) activity is absent." [PomBase:mah] synonym: "abolished 'malic' enzyme activity" RELATED [GO:0004471] synonym: "abolished (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "abolished malate dehydrogenase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "abolished NAD-linked malic enzyme activity" RELATED [GO:0004471] synonym: "abolished NAD-malic enzyme activity" BROAD [GO:0004471] synonym: "abolished NAD-specific malic enzyme activity" RELATED [GO:0004471] synonym: "malate dehydrogenase (decarboxylating) (NAD+) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002621 ! abnormal malate dehydrogenase (decarboxylating) (NAD+) activity created_by: midori creation_date: 2014-06-11T12:17:05Z [Term] id: FYPO:0003419 name: increased malate dehydrogenase (decarboxylating) (NAD+) activity def: "A molecular function phenotype in which the observed rate of malate dehydrogenase (decarboxylating) (NAD+) activity is increased." [PomBase:mah] synonym: "increased 'malic' enzyme activity" RELATED [GO:0004471] synonym: "increased (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "increased malate dehydrogenase (oxaloacetate-decarboxylating) activity" EXACT [GO:0004471] synonym: "increased NAD-linked malic enzyme activity" RELATED [GO:0004471] synonym: "increased NAD-malic enzyme activity" BROAD [GO:0004471] synonym: "increased NAD-specific malic enzyme activity" RELATED [GO:0004471] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002621 ! abnormal malate dehydrogenase (decarboxylating) (NAD+) activity created_by: midori creation_date: 2014-06-11T12:18:56Z [Term] id: FYPO:0003420 name: increased cellular glutathione level during cellular response to cadmium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is higher than normal during a cellular response to cadmium." [PomBase:mah] synonym: "increased cellular glutathione level during cellular response to cadmium" EXACT [PomBase:mah] synonym: "increased cellular glutathione level during cellular response to cadmium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular glutathione level during cellular response to cadmium during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular GSH level during cellular response to cadmium" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular L-gamma-glutamyl-L-cysteinylglycine level during cellular response to cadmium" EXACT [CHEBI:16856] synonym: "increased cellular reduced glutathione level during cellular response to cadmium" EXACT [CHEBI:16856, PomBase:al] synonym: "increased glutathione accumulation during cellular response to cadmium" RELATED [PomBase:mah] is_a: FYPO:0001521 ! increased cellular glutathione level during vegetative growth created_by: midori creation_date: 2014-06-11T13:03:52Z [Term] id: FYPO:0003421 name: decreased cellular nitric oxide level during cellular response to cadmium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is lower than normal during a cellular response to cadmium." [PomBase:mah] synonym: "decreased cellular nitric oxide level during cellular response to cadmium" EXACT [PomBase:mah] synonym: "decreased cellular nitric oxide level during cellular response to cadmium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular nitric oxide level during cellular response to cadmium during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular NO level during cellular response to cadmium" EXACT [CHEBI:16480] synonym: "decreased nitric oxide accumulation during cellular response to cadmium" RELATED [PomBase:mah] synonym: "reduced cellular nitric oxide level during cellular response to cadmium" EXACT [PomBase:mah] is_a: FYPO:0003127 ! decreased cellular nitric oxide level during vegetative growth created_by: midori creation_date: 2014-06-11T13:06:05Z [Term] id: FYPO:0003422 name: inviable after spore germination, multiple cell divisions, elongated multiseptate tapered cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and tapered, i.e. tapers at one end to a diameter smaller than the other, contains more than one septum, and undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated multiseptate bottle-shaped cell" EXACT [PomBase:vw] synonym: "inviable after spore germination, multiple cell divisions, elongated multiseptate bottle/skittle cell" EXACT [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated multiseptate skittle-shaped cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, elongated multiseptate tapered cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, elongated multiseptate tapered cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, elongated multiseptate tapered cell" EXACT [PomBase:mah] is_a: FYPO:0001494 ! inviable elongated multiseptate vegetative cell is_a: FYPO:0002450 ! inviable after spore germination, multiple cell divisions, septated cell with abnormal morphology is_a: FYPO:0002733 ! inviable after spore germination, multiple cell divisions, elongated tapered cell created_by: midori creation_date: 2014-06-11T13:17:31Z [Term] id: FYPO:0003423 name: decreased mitochondrial RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial RNA measured in a cell is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mitochondrial RNA accumulation" RELATED [PomBase:mah] synonym: "decreased mitochondrial RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitochondrial transcript level" EXACT [PomBase:vw] synonym: "decreased RNA level in mitochondrion" EXACT [PomBase:mah] synonym: "reduced mitochondrial RNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0004958 ! altered RNA level in mitochondrion created_by: midori creation_date: 2014-06-11T13:44:20Z [Term] id: FYPO:0003424 name: increased mitochondrial RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial RNA measured in a cell is greater than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mitochondrial RNA accumulation" RELATED [PomBase:mah] synonym: "increased mitochondrial RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitochondrial RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitochondrial transcript level" EXACT [PomBase:vw] synonym: "increased RNA level in mitochondrion" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0004958 ! altered RNA level in mitochondrion created_by: midori creation_date: 2014-06-11T13:58:16Z [Term] id: FYPO:0003425 name: abolished protein-protein interaction during cellular response to rapamycin def: "A molecular function phenotype in which the binding of one protein to another does not occur during a cellular response to rapamycin. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished protein binding during cellular response to rapamycin" EXACT [PomBase:mah] synonym: "protein-protein interaction abolished during cellular response to rapamycin" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction created_by: midori creation_date: 2014-06-11T14:14:35Z [Term] id: FYPO:0003426 name: decreased RNA level during cellular response to pheromone def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to a pheromone is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to pheromone" RELATED [PomBase:mah] synonym: "decreased transcript level during cellular response to pheromone" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2014-06-11T14:16:53Z [Term] id: FYPO:0003427 name: decreased queuosine level in tRNA def: "A phenotype in which one or more transfer RNA (tRNA) molecules contains fewer queuosine residues than normal." [PMID:24911101, PomBase:mah] synonym: "reduced queuosine content of tRNA" EXACT [PomBase:vw] synonym: "reduced queuosine level in tRNA" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-06-11T14:25:29Z [Term] id: FYPO:0003428 name: growth auxotrophic for arginine and cysteine def: "Auxotrophy in which a cell is unable to synthesize arginine or cysteine, and therefore requires arginine and cysteine in the medium for vegetative cell growth." [PomBase:mah] synonym: "arginine and cysteine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for arginine and cysteine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for arginine and cysteine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000035 ! growth auxotrophic for arginine is_a: FYPO:0000037 ! growth auxotrophic for cysteine created_by: midori creation_date: 2014-06-11T14:41:35Z [Term] id: FYPO:0003429 name: short interphase microtubules present in decreased numbers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, and shorter, cytoplasmic microtubules than normal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "short cytoplasmic microtubules present in decreased numbers during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "short cytoplasmic microtubules present in decreased numbers during mitotic interphase" EXACT [PomBase:mah] synonym: "short interphase cytoplasmic microtubules present in decreased numbers" EXACT [PomBase:mah] synonym: "short interphase microtubules present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "short interphase microtubules present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0003430 ! microtubules present in decreased numbers is_a: FYPO:0006103 ! short interphase microtubules created_by: midori creation_date: 2014-06-11T14:54:21Z [Term] id: FYPO:0003430 name: microtubules present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer microtubules than normal." [PomBase:mah] synonym: "decreased level of MTs" EXACT [PomBase:mah] synonym: "microtubules present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "microtubules present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "microtubules present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2014-06-11T14:56:12Z [Term] id: FYPO:0003431 name: abolished histone H3K9me binding def: "A molecular function phenotype in which the binding of a protein to histone H3 methylated on the lysine at position 9 does not occur." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished K9-methylated histone H3 binding" EXACT [PomBase:mah] synonym: "abolished protein-histone H3K9me interaction" EXACT [PomBase:mah] synonym: "histone H3K9me binding abolished" EXACT [PomBase:mah] is_a: FYPO:0003247 ! abolished histone H3 binding created_by: midori creation_date: 2014-06-11T14:58:37Z [Term] id: FYPO:0003432 name: normal histone H3K9me binding def: "A molecular function phenotype in which the binding of a protein to histone H3 methylated on the lysine at position 9 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal K9-methylated histone H3 binding" EXACT [PomBase:mah] synonym: "normal methylated histone H3K9me binding" EXACT [PomBase:al] is_a: FYPO:0000703 ! normal protein-protein interaction created_by: midori creation_date: 2014-06-11T15:01:04Z [Term] id: FYPO:0003433 name: abnormal ornithine carbamoyltransferase activity def: "A molecular function phenotype in which the observed rate of ornithine carbamoyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-06-11T15:26:37Z [Term] id: FYPO:0003434 name: decreased ornithine carbamoyltransferase activity def: "A molecular function phenotype in which the observed rate of ornithine carbamoyltransferase activity is decreased." [PomBase:mah] synonym: "reduced ornithine carbamoyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003433 ! abnormal ornithine carbamoyltransferase activity created_by: midori creation_date: 2014-06-11T15:26:44Z [Term] id: FYPO:0003435 name: increased ornithine carbamoyltransferase activity def: "A molecular function phenotype in which the observed rate of ornithine carbamoyltransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003433 ! abnormal ornithine carbamoyltransferase activity created_by: midori creation_date: 2014-06-11T15:27:00Z [Term] id: FYPO:0003436 name: decreased protein kinase activity during mitotic G2 phase def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the G2 phase of the mitotic cell cycle." [PomBase:mah] synonym: "reduced protein kinase activity during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0003331 ! decreased protein kinase activity during mitotic interphase created_by: midori creation_date: 2014-06-16T11:26:31Z [Term] id: FYPO:0003437 name: abolished protein kinase activity during mitotic G1 phase def: "A molecular function phenotype in which a protein kinase activity is absent during G1 phase of the mitotic cell cycle." [PomBase:mah] synonym: "protein kinase activity abolished during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0001384 ! abolished protein kinase activity created_by: midori creation_date: 2014-06-16T11:30:42Z [Term] id: FYPO:0003438 name: mitotic G1/S phase transition delay following nitrogen starvation-induced G1 phase arrest def: "A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle begins later than normal after the cell has been arrested in G1 phase due to nitrogen starvation. The duration of G1 arrest is thus longer than normal." [PMID:8657126, PomBase:mah] comment: A G1/S delay may indicate that a checkpoint, such as the cell size checkpoint or the G1/S DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "delayed cell cycle progression through mitotic G1/S phase transition following cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed mitotic G1 phase progression following nitrogen starvation-induced G1 phase arrest" RELATED [PomBase:mah] synonym: "increased duration of nitrogen starvation-induced mitotic G1 phase arrest" RELATED [PomBase:mah] synonym: "mitotic cell cycle delay at G1/S transition following nitrogen starvation-induced G1 phase arrest" EXACT [PomBase:mah] synonym: "mitotic G1/S phase transition delay after recovery from nitrogen starvation-induced G1 arrest" EXACT [PMID:8657126, PomBase:vw] synonym: "mitotic G1/S transition delay following nitrogen starvation-induced G1 phase arrest" EXACT [PomBase:mah] is_a: FYPO:0000333 ! mitotic G1/S phase transition delay created_by: midori creation_date: 2014-06-16T11:54:10Z [Term] id: FYPO:0003439 name: branched septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that has branches. For example, the septum may be Y-shaped." [PMID:24798735, PomBase:mah] synonym: "branched septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2014-06-16T12:06:23Z [Term] id: FYPO:0003440 name: cell lysis during cytokinesis def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during cytokinesis. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PMID:24798735, PomBase:mah] synonym: "cell lysis during cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell lysis during cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "cytolysis during cytokinesis" EXACT [PomBase:mah] synonym: "inviable, lysed cell during cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000647 ! vegetative cell lysis created_by: midori creation_date: 2014-06-16T12:21:54Z [Term] id: FYPO:0003441 name: normal protein localization to actin cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the actin cytoskeleton is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to actin cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to actin cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-06-16T12:40:07Z [Term] id: FYPO:0003442 name: abolished protein localization to actin cable def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more actin cables does not occur. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to actin cable" EXACT [PomBase:mah] synonym: "abolished protein localization to actin cable during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to formin-nucleated actin cable" EXACT [GO:0070648] synonym: "protein absent from actin cable" RELATED [PomBase:mah] synonym: "protein localization to actin cable abolished" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0006096 ! abnormal protein localization to actin cable created_by: midori creation_date: 2014-06-16T12:46:59Z [Term] id: FYPO:0003443 name: decreased medial cortical node movement during contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which medial cortical nodes move less frequently, and over shorter distances, than normal. During contractile ring assembly, medial cortical nodes normally move towards the cell center, and condense into a ring." [PMID:24798735, PomBase:al, PomBase:mah] synonym: "decreased medial cortical node movement during actomyosin contractile ring assembly" EXACT [PomBase:vw] synonym: "decreased medial cortical node movement during contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased medial cortical node movement during contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced medial cortical node movement during contractile ring assembly" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2014-06-16T12:56:48Z [Term] id: FYPO:0003444 name: abnormal medial cortical node condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which medial cortical nodes move in random directions such that they do not undergo an overall movement towards the cell center. During contractile ring assembly, medial cortical nodes normally move towards the cell center, and condense into a ring." [PMID:24798735, PomBase:al, PomBase:mah] synonym: "abnormal medial cortical node condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal medial cortical node condensation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal medial cortical node migration" EXACT [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2014-06-16T13:01:12Z [Term] id: FYPO:0003445 name: increased duration of mitotic DNA damage checkpoint during cellular response to UV def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ultraviolet light." [PomBase:mah] synonym: "delayed DNA damage checkpoint deactivation during cellular response to UV" EXACT [PomBase:mah] synonym: "prolonged DNA damage checkpoint during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0002341 ! increased duration of mitotic DNA damage checkpoint is_a: FYPO:0002900 ! abnormal mitotic DNA damage checkpoint during cellular response to UV created_by: midori creation_date: 2014-06-16T13:23:07Z [Term] id: FYPO:0003446 name: decreased SRP-dependent cotranslational protein targeting to membrane during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of SRP-dependent cotranslational protein targeting to the ER membrane is decreased." [GO:0006614, PomBase:mah] synonym: "decreased SRP-dependent cotranslational protein targeting to membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced SRP-dependent cotranslational protein targeting to membrane during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport during vegetative growth is_a: FYPO:0000536 ! abnormal protein secretion during vegetative growth created_by: midori creation_date: 2014-06-16T13:37:29Z [Term] id: FYPO:0003447 name: decreased level of glycosylated protein in cell def: "A cell phenotype in which the amount of glycosylated protein measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased accumulation of glycosylated protein in cell" RELATED [PomBase:mah] synonym: "decreased cellular glycoprotein level" EXACT [PR:000037069] synonym: "decreased glycosylated protein level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of glycosylated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of glycosylated protein in cell during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of glycosylated protein in cell" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-06-16T13:49:35Z [Term] id: FYPO:0003448 name: viable swollen vacuolated spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, is shaped in the form of a spheroid, has a larger volume than normal, and in which vacuoles are more visible (usually by microscopy) than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "viable enlarged vacuolated spheroid vegetative cell" RELATED [PomBase:mah] synonym: "viable enlarged volume vacuolated spheroid vegetative cell" EXACT [PomBase:mah] synonym: "viable large vacuolated spheroid vegetative cell" RELATED [PomBase:vw] synonym: "viable swollen rounded vacuolated vegetative cell" EXACT [PomBase:mah] synonym: "viable swollen vacuolated spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable swollen vacuolated spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0004559 ! viable swollen spheroid vegetative cell relationship: has_part FYPO:0001581 ! vacuolated created_by: midori creation_date: 2014-06-16T13:51:06Z [Term] id: FYPO:0003449 name: abnormal cell cycle arrest at mitotic G1/S phase transition alt_id: FYPO:0000395 def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G1/S phase transition, under conditions where arrest is not a normal occurrence." [PomBase:mah] comment: Use this term for terminal arrest. If arrest is transient, consider using 'mitotic G1/S transition delay' (FYPO:0000333). synonym: "abnormal cell cycle arrest at G1/S phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest with unreplicated DNA at mitotic G1/S phase transition" EXACT [PomBase:vw] synonym: "abnormal mitotic cell cycle arrest at G1/S phase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic G1/S phase arrest" EXACT [PomBase:mah] synonym: "abolished mitotic G1/S phase transition" RELATED [PomBase:mah] synonym: "cell cycle arrest at mitotic G1/S phase transition" EXACT [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: arrested" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001430 ! abnormal mitotic cell cycle arrest with unreplicated DNA is_a: FYPO:0005097 ! abnormal cell cycle arrest in mitotic G1 phase created_by: midori creation_date: 2014-06-24T11:44:29Z [Term] id: FYPO:0003450 name: abolished protein localization to nucleus def: "A cell phenotype in which the localization of a protein to the nucleus is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus" EXACT [PomBase:mah] synonym: "nuclear exclusion" RELATED [PomBase:vw] synonym: "nuclear protein exclusion" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished" EXACT [PomBase:mah] is_a: FYPO:0002956 ! abnormal protein localization to nucleus created_by: midori creation_date: 2014-06-24T12:15:23Z [Term] id: FYPO:0003451 name: abolished protein localization to nucleus during meiotic anaphase II def: "A cell phenotype in which the localization of a protein to the nucleus is abolished during anaphase of the second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during meiotic anaphase II" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during anaphase II" EXACT [PomBase:al] synonym: "nuclear exclusion during meiotic anaphase II" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during meiotic anaphase II" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during meiotic anaphase II" EXACT [PomBase:mah] is_a: FYPO:0003450 ! abolished protein localization to nucleus created_by: midori creation_date: 2014-06-24T12:17:48Z [Term] id: FYPO:0003452 name: mislocalized protein def: "A cell phenotype in which a protein is observed in a particular location where it is not normally found." [PomBase:mah] comment: The difference between this term and 'abnormal protein localization' (FYPO:0000443) is that 'mislocalized protein' describes a protein that is observed in a place where it is not normally found, whereas 'abnormal protein localization' additionally encompasses the absence of protein from a place where it is normally found. FYPO:0003452 and its descendants can therefore be used in any case where a protein is in a different location in a mutant compared to wild type, whereas additional information is usually required to support annotation to FYPO:0000443 or its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein" EXACT [PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype relationship: output_of FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2014-06-24T12:20:58Z [Term] id: FYPO:0003453 name: protein mislocalized to nucleus def: "A cell phenotype in which a protein that is not normally found in the nucleus is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleus" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleus" EXACT [PomBase:mah] is_a: FYPO:0003452 ! mislocalized protein created_by: midori creation_date: 2014-06-24T12:22:14Z [Term] id: FYPO:0003454 name: protein mislocalized to nucleus during meiosis I def: "A cell phenotype in which a protein that is not normally found in the nucleus is observed there during the first meiotic nuclear division." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleus during meiosis I" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleus during meiosis I" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003453 ! protein mislocalized to nucleus created_by: midori creation_date: 2014-06-24T12:29:34Z [Term] id: FYPO:0003455 name: decreased arginine catabolic process to proline def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of the breakdown of arginine into other compounds, including proline, is decreased." [GO:0019493, PomBase:mah] synonym: "decreased arginine catabolic process to proline during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased arginine catabolic process to proline during vegetative growth" EXACT [PomBase:mah] synonym: "decreased arginine catabolism to proline" EXACT [PomBase:mah] synonym: "reduced arginine catabolic process to proline" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-06-24T12:50:35Z [Term] id: FYPO:0003456 name: growth auxotrophic for methionine and purine def: "Auxotrophy in which a cell is unable to synthesize methionine or purines, and therefore requires methionine and at least one purine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for methionine and purine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for methionine and purine during vegetative growth" EXACT [PomBase:mah] synonym: "methionine and purine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000040 ! growth auxotrophic for methionine created_by: midori creation_date: 2014-06-24T13:28:57Z [Term] id: FYPO:0003457 name: increased cellular homocysteine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of homocysteine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular homocysteine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular homocysteine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased homocysteine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-06-24T13:36:34Z [Term] id: FYPO:0003458 name: alpha,alpha-trehalase activity increase abolished during cellular response to salt stress def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a salt stress stimulus." [PomBase:mah] synonym: "absent increase in trehalase activity in response to salt stress" EXACT [PomBase:al] synonym: "neutral trehalase activity increase abolished during cellular response to salt stress" EXACT [PomBase:mah] synonym: "trehalase activity increase abolished during cellular response to salt stress" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-06-24T13:40:09Z [Term] id: FYPO:0003459 name: decreased cellular trehalose level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to salt stress." [PomBase:mah] synonym: "decreased cellular trehalose level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular trehalose level during vegetative growth and during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased cellular trehalose level in response to salt stress" EXACT [PomBase:al] synonym: "decreased trehalose accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001447 ! decreased cellular trehalose level created_by: midori creation_date: 2014-06-24T14:03:51Z [Term] id: FYPO:0003460 name: decreased cellular trehalose level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to oxidative stress." [PomBase:mah] synonym: "decreased cellular trehalose level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular trehalose level during oxidative stress response" EXACT [PomBase:vw] synonym: "decreased cellular trehalose level during vegetative growth and during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "decreased cellular trehalose level in response to oxidative stress" EXACT [PomBase:al] synonym: "decreased trehalose accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0001447 ! decreased cellular trehalose level created_by: midori creation_date: 2014-06-24T14:05:22Z [Term] id: FYPO:0003461 name: normal cellular trehalose level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is subject to salt stress." [PomBase:mah] synonym: "normal cellular trehalose accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001449 ! normal cellular trehalose level created_by: midori creation_date: 2014-06-24T14:06:56Z [Term] id: FYPO:0003462 name: normal cellular trehalose level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is subject to oxidative stress." [PomBase:mah] synonym: "normal cellular trehalose accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular trehalose level during oxidative stress response" EXACT [PomBase:vw] is_a: FYPO:0001449 ! normal cellular trehalose level created_by: midori creation_date: 2014-06-24T14:08:13Z [Term] id: FYPO:0003463 name: abolished alpha,alpha-trehalase activity def: "A molecular function phenotype in which alpha,alpha-trehalase activity is absent." [PomBase:mah] synonym: "abolished neutral trehalase activity" EXACT [PomBase:mah] synonym: "abolished trehalase activity" BROAD [GO:0004555] synonym: "alpha,alpha-trehalase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-06-24T14:14:04Z [Term] id: FYPO:0003464 name: decreased alpha,alpha-trehalase activity during cellular response to heat def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during a cellular response to heat." [PomBase:mah] synonym: "decreased neutral trehalase activity during cellular response to heat" EXACT [PomBase:mah] synonym: "decreased trehalase activity during cellular response to heat" BROAD [GO:0004555, GO:0015927] synonym: "reduced alpha,alpha-trehalase activity during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-06-24T14:24:58Z [Term] id: FYPO:0003465 name: decreased alpha,alpha-trehalase activity during cellular response to salt stress def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during a cellular response to salt stress." [PomBase:mah] synonym: "decreased neutral trehalase activity during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased trehalase activity during cellular response to salt stress" BROAD [GO:0004555, GO:0015927] synonym: "reduced alpha,alpha-trehalase activity during cellular response to v" EXACT [PomBase:mah] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2014-06-24T14:27:25Z [Term] id: FYPO:0003466 name: normal cellular trehalose level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is subject to a heat stimulus." [PomBase:mah] synonym: "normal cellular trehalose accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001449 ! normal cellular trehalose level created_by: midori creation_date: 2014-06-24T14:28:19Z [Term] id: FYPO:0003467 name: altered splice site specificity def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA splice site specificity differs from normal. For example, different exons may be included or excluded, or introns in which the normally recognized 3' splice site AG nucleotides are mutated may be spliced." [PMID:1617727, PMID:17130122, PomBase:mah] synonym: "abnormal splice site specificity" EXACT [PomBase:mah] synonym: "altered splice site specificity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered splice site specificity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002915 ! abnormal RNA splicing, via spliceosome created_by: midori creation_date: 2014-06-24T14:40:45Z [Term] id: FYPO:0003468 name: normal RNA splicing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA splicing is normal (i.e. indistinguishable from wild type). All RNA splicing may be normal, or one splicing of or more specific RNA molecules may be specifically assayed." [PomBase:mah] synonym: "normal RNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA splicing during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" EXACT [GO:0000377] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-06-24T14:46:38Z [Term] id: FYPO:0003469 name: normal snRNA splicing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which small nuclear RNA (snRNA) splicing is normal (i.e. indistinguishable from wild type). All snRNA splicing may be normal, or one splicing of or more specific snRNA molecules may be specifically assayed." [PomBase:mah] synonym: "normal snRNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal snRNA splicing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001980 ! normal RNA processing is_a: FYPO:0003468 ! normal RNA splicing created_by: midori creation_date: 2014-06-24T14:47:50Z [Term] id: FYPO:0003470 name: increased mRNA splicing, via spliceosome def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is increased." [PMID:24298023, PomBase:mah] synonym: "increased mRNA splicing, via spliceosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] synonym: "increased nuclear mRNA splicing, via spliceosome" EXACT [PomBase:mah] synonym: "increased splicing" BROAD [PomBase:al] is_a: FYPO:0000189 ! abnormal mRNA splicing, via spliceosome created_by: midori creation_date: 2014-06-24T14:49:33Z [Term] id: FYPO:0003471 name: obsolete multiseptate cell during cellular response to salt stress def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has more than one septum apiece during a cellular response to salt stress." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "multiseptate cell during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiseptate cell during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "multiseptate in response to salt stress" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2014-06-24T15:00:17Z [Term] id: FYPO:0003472 name: obsolete cut during cellular response to salt stress def: "OBSOLETE. A cut phenotype that is observed when a cell is subject to salt stress. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation during cellular response to salt stress" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2014-06-24T15:01:30Z [Term] id: FYPO:0003473 name: septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to salt stress def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, producing inviable daughter cells, and in which the septum forms in a position that partitions both nuclei into one compartment, when the cell is subject to salt stress. Cell separation may or may not be completed." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155) or its descendants, because these phenotypes often co-occur. synonym: "septation following abnormal chromosome segregation, with anucleate cell formation during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septation following abnormal chromosome segregation, with anucleate cell formation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal chromosome segregation, with binucleate cell formation during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0003166 ! monoseptate vegetative cell with binucleate and anucleate compartments created_by: midori creation_date: 2014-06-24T15:05:37Z [Term] id: FYPO:0003474 name: fragmented nucleus during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which nucleus is broken into multiple small fragments that are smaller than a normal nucleus, hen the cell is subject to salt stress." [PomBase:mah] synonym: "fragmented nuclear DNA during cellular response to salt stress" RELATED [PomBase:mah] synonym: "fragmented nucleus during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fragmented nucleus during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "loss of nuclear integrity during cellular response to salt stress" RELATED [PomBase:al] is_a: FYPO:0001919 ! fragmented nucleus during vegetative growth created_by: midori creation_date: 2014-06-24T15:12:19Z [Term] id: FYPO:0003475 name: abnormal arsenate reductase activity def: "A molecular function phenotype in which the observed rate of arsenate reductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-06-24T15:22:07Z [Term] id: FYPO:0003476 name: decreased arsenate reductase activity def: "A molecular function phenotype in which the observed rate of arsenate reductase activity is decreased." [PomBase:mah] synonym: "reduced arsenate reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003475 ! abnormal arsenate reductase activity created_by: midori creation_date: 2014-06-24T15:22:14Z [Term] id: FYPO:0003477 name: abolished protein phosphorylation during cellular response to arsenic-containing substance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to an arsenic-containing substance such as arsenate." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to arsenate" NARROW [PMID:22912829, PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to arsenic-containing substance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to arsenic-containing substance during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to arsenic-containing substance" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-06-24T15:28:25Z [Term] id: FYPO:0003478 name: signal transduction phenotype def: "A cellular process phenotype that affects signal transduction. Signal transduction is the process in which a signal is conveyed to trigger a change in the activity or state of a cell. It begins with reception of a signal and ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. A phenotype may affect one or more steps in one or more signal transduction pathways." [GO:0007165, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast signal transduction phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2014-07-01T12:26:39Z [Term] id: FYPO:0003479 name: constitutively activated MAPK cascade involved in cell wall organization or biogenesis def: "A signal transduction phenotype in which the MAPK cascade involved in cell wall organization or biogenesis is activated continuously." [PMID:23934882, PomBase:mah] synonym: "constitutively activated MAPK cascade involved in cell wall organisation or biogenesis" EXACT [PomBase:mah] synonym: "constitutively activated Pmk1 MAPK cell integrity signaling" NARROW [GO:0000196, PomBase:vw] synonym: "continuous MAPK cascade involved in cell wall organization or biogenesis" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0003478 ! signal transduction phenotype created_by: midori creation_date: 2014-07-01T12:29:40Z [Term] id: FYPO:0003480 name: queuosine absent from tRNA def: "A phenotype in which one or more transfer RNA (tRNA) molecules contains no queuosine residues." [PMID:24911101, PomBase:mah] is_a: FYPO:0003427 ! decreased queuosine level in tRNA created_by: midori creation_date: 2014-07-01T13:04:14Z [Term] id: FYPO:0003481 name: viable elongated vegetative cell, elongated upon mitotic entry def: "A cell morphology phenotype in which a vegetative cell is viable and elongated, and in which mitosis begins when the cell is longer than normal." [PMID:24013504, PomBase:mah] synonym: "viable elongated vegetative cell with entry into mitosis at increased length" EXACT [PomBase:vw] synonym: "viable elongated vegetative cell with mitotic entry at increased length" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell, elongated upon entry into mitosis" EXACT [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell relationship: output_of FYPO:0000012 ! mitotic G2/M phase transition delay created_by: midori creation_date: 2014-07-01T13:27:12Z [Term] id: FYPO:0003482 name: increased punctate cytoplasmic protein localization def: "A cell phenotype in which a protein is localized to discrete regions in the cytoplasm, visible as foci or dots by microscopy, to a greater extent observed than in normal (wild type) cells." [PomBase:mah] comment: This term can be used for proteins that do not normally localize to discrete cytoplasmic regions, or for proteins that do normally show punctate localization but with such localization increased in a mutant. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localization to cytoplasmic puncta" EXACT [PomBase:vw] synonym: "increased punctate cytoplasmic protein localisation" EXACT [PomBase:mah] synonym: "increased punctate cytoplasmic protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased punctate cytoplasmic protein localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2014-07-01T13:51:07Z [Term] id: FYPO:0003483 name: decreased punctate nuclear protein localization during cellular response to ionizing radiation def: "A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that fewer dots are observed than in normal (wild type) cells during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased punctate nuclear protein localisation during cellular response to ionising radiation" EXACT [PomBase:mah] synonym: "decreased punctate nuclear protein localization during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased punctate nuclear protein localization during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased punctate nuclear protein localization during cellular response to IR" EXACT [PomBase:mah] synonym: "reduced punctate nuclear protein localization during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0002624 ! decreased punctate nuclear protein localization created_by: midori creation_date: 2014-07-01T15:39:31Z [Term] id: FYPO:0003484 name: abolished protein localization to mitotic spindle midzone def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1902967, GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to mitotic spindle midzone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from mitotic spindle midzone" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle midzone abolished" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle midzone abolished" EXACT [PomBase:mah] synonym: "protein localization to spindle midzone abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0004883 ! abnormal protein localization to mitotic spindle midzone created_by: midori creation_date: 2014-07-01T15:44:04Z [Term] id: FYPO:0003485 name: abolished DNA synthesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of DNA does not occur." [GO:0071897, PomBase:mah] synonym: "abolished DNA biosynthesis" EXACT [GO:0071897] synonym: "abolished DNA biosynthetic process" EXACT [GO:0071897] synonym: "abolished DNA synthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished DNA synthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-07-01T15:52:26Z [Term] id: FYPO:0003486 name: abolished protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "abolished protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to site of double-strand break" EXACT [PomBase:mah] synonym: "protein localization to double-strand break site abolished" EXACT [PomBase:mah] is_a: FYPO:0002473 ! abnormal protein localization to double-strand break site created_by: midori creation_date: 2014-07-01T16:23:35Z [Term] id: FYPO:0003487 name: obsolete cut during cellular response to ionizing radiation def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to ionizing radiation. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "cut during cellular response to IR" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation during cellular response to ionizing radiation" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2014-07-01T16:26:15Z [Term] id: FYPO:0003488 name: obsolete elongated cell during cellular response to ionizing radiation def: "OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated during a cellular response to ionizing radiation." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated cell during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated cell during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "elongated cell during cellular response to IR" EXACT [PomBase:mah] synonym: "elongated in response to ionizing radiation" EXACT [PomBase:al] is_obsolete: true created_by: midori creation_date: 2014-07-01T16:27:33Z [Term] id: FYPO:0003489 name: abnormal mitotic cell cycle regulation during cellular response to ionizing radiation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation. The most common abnormality is for the cell cycle to progress as in the absence of ionizing radiation." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to ionizing radiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following ionizing radiation" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to IR" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-07-01T16:28:40Z [Term] id: FYPO:0003490 name: increased duration of mitotic DNA damage checkpoint during cellular response to ionizing radiation def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ionizing radiation." [PomBase:mah] synonym: "delayed mitotic DNA damage checkpoint deactivation during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "increased duration of mitotic DNA damage checkpoint during cellular response to IR" EXACT [PomBase:mah] synonym: "prolonged mitotic DNA damage checkpoint during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0002341 ! increased duration of mitotic DNA damage checkpoint is_a: FYPO:0003489 ! abnormal mitotic cell cycle regulation during cellular response to ionizing radiation created_by: midori creation_date: 2014-07-01T16:30:58Z [Term] id: FYPO:0003491 name: sensitive to UV during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light during G1 phase of the mitotic cell cycle." [PomBase:mah] synonym: "decreased growth during cellular response to UV during mitotic G1 phase" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to UV during mitotic G1 phase" EXACT [PomBase:mah] synonym: "hypersensitive to UV during mitotic G1 phase" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation during mitotic G1 phase" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light during mitotic G1 phase" EXACT [PomBase:mah] synonym: "sensitive to UV during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to UV during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000268 ! sensitive to UV during vegetative growth created_by: midori creation_date: 2014-07-01T16:33:46Z [Term] id: FYPO:0003492 name: resistance to beta-glucanase def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of beta-glucanase, any enzyme that degrades cell wall polysaccharides by hydrolyzing beta-glucan linkages, than normal." [PomBase:mah] synonym: "resistance to beta-glucanase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to beta-glucanase during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to beta-glucanase" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-07-01T16:35:58Z [Term] id: FYPO:0003493 name: resistance to hypothemycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hypothemycin than normal." [PomBase:mah] synonym: "resistance to hypothemycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to hypothemycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to hypothemycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-07-01T16:43:41Z [Term] id: FYPO:0003494 name: sensitive to L-azetidine-2-carboxylic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-azetidine-2-carboxylic acid. Cells stop growing (and may die) at a concentration of L-azetidine-2-carboxylic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to L-azetidine-2-carboxylic acid" EXACT [PomBase:mah] synonym: "sensitive to (S)-azetidine-2-carboxylic acid" EXACT [CHEBI:6198, PomBase:mah] synonym: "sensitive to AZC" BROAD [PomBase:mah] synonym: "sensitive to L-azetidine-2-carboxylic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to L-azetidine-2-carboxylic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-07-01T16:48:29Z [Term] id: FYPO:0003495 name: abnormal azetidine-2-carboxylic acid acetyltransferase activity def: "A molecular function phenotype in which the observed rate of azetidine-2-carboxylic acid acetyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-07-01T16:51:16Z [Term] id: FYPO:0003496 name: abolished azetidine-2-carboxylic acid acetyltransferase activity def: "A molecular function phenotype in which azetidine-2-carboxylic acid acetyltransferase activity is absent." [PomBase:mah] synonym: "azetidine-2-carboxylic acid acetyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003495 ! abnormal azetidine-2-carboxylic acid acetyltransferase activity created_by: midori creation_date: 2014-07-01T16:51:26Z [Term] id: FYPO:0003497 name: increased azetidine-2-carboxylic acid acetyltransferase activity def: "A molecular function phenotype in which the observed rate of azetidine-2-carboxylic acid acetyltransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003495 ! abnormal azetidine-2-carboxylic acid acetyltransferase activity created_by: midori creation_date: 2014-07-01T16:51:50Z [Term] id: FYPO:0003498 name: premature mitotic DNA replication initiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins earlier than normal." [PMID:22970243, PomBase:mah] synonym: "advanced mitotic DNA replication initiation" EXACT [PomBase:mah] synonym: "premature DNA replication initiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature DNA replication initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001344 ! abnormal mitotic DNA replication initiation relationship: output_of FYPO:0001248 ! abnormal regulation of mitotic DNA replication initiation created_by: midori creation_date: 2014-07-01T16:56:35Z [Term] id: FYPO:0003499 name: increased rate of pre-replicative complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of pre-replicative complex assembly is increased." [PMID:22970243, PomBase:mah] synonym: "increased rate of MCM complex loading" NARROW [PMID:22970243, PomBase:vw] synonym: "increased rate of pre-RC assembly" EXACT [PomBase:mah] synonym: "increased rate of pre-replicative complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of pre-replicative complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000773 ! abnormal pre-replicative complex assembly created_by: midori creation_date: 2014-07-01T17:00:14Z [Term] id: FYPO:0003500 name: viable branched, elongated, multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, forms one or more branches near a septum, is elongated, and has more than one septum." [PomBase:mah] synonym: "viable branched, elongated, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, elongated, multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable branched, long, multiseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000134 ! branched, elongated, multiseptate cell is_a: FYPO:0001496 ! viable elongated multiseptate vegetative cell is_a: FYPO:0002459 ! viable branched, elongated vegetative cell created_by: midori creation_date: 2014-07-01T17:16:27Z [Term] id: FYPO:0003501 name: inviable aseptate mononucleate vegetative cell, normal cell length def: "A cell phenotype in which a cell is inviable, is normal length, and contains one nucleus and no septum." [PomBase:mah] synonym: "inviable aseptate mononucleate cell, normal cell length, during vegetative growth" EXACT [PomBase:mah] synonym: "inviable aseptate mononucleate vegetative cell, normal cell length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell, normal cell length" EXACT [PomBase:mah] synonym: "inviable unseptated mononucleate vegetative cell with normal cell length" EXACT [PomBase:mah] synonym: "lethal; aseptate mononucleate vegetative cell, normal cell length" EXACT [PomBase:mah] is_a: FYPO:0003503 ! normal vegetative cell length is_a: FYPO:0003763 ! inviable aseptate mononucleate vegetative cell relationship: has_part FYPO:0003503 ! normal vegetative cell length created_by: midori creation_date: 2014-07-01T17:19:22Z [Term] id: FYPO:0003502 name: abolished cell population growth on raffinose carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing raffinose as the carbon source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with raffinose as the carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on raffinose carbon source" BROAD [PomBase:mah] synonym: "abolished raffinose utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on raffinose carbon source" EXACT [PomBase:mah] synonym: "cell population growth on raffinose carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0001162 ! decreased cell population growth on raffinose carbon source is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2014-07-01T17:25:43Z [Term] id: FYPO:0003503 name: normal vegetative cell length def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal length." [PomBase:mah] synonym: "normal cell length during vegetative growth" EXACT [PomBase:mah] synonym: "normal vegetative cell length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2014-07-01T17:33:44Z [Term] id: FYPO:0003504 name: increased protein level in plasma membrane def: "A cell phenotype in which the amount of protein measured in the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: An increased level of a protein in the plasma membrane may result from increased protein transport to the membrane ('increased protein localization to plasma membrane FYPO:0002127), decreased endocytosis from the membrane ('abolished endocytosis' FYPO:0000421 or 'decreased endocytosis' FYPO:0000422), or both. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased plasma membrane protein level during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level in cell membrane during vegetative growth" EXACT [GO:0005886] synonym: "increased protein level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "protein accumulation in plasma membrane" EXACT [PomBase:vw] is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth created_by: midori creation_date: 2014-07-08T13:56:41Z [Term] id: FYPO:0003505 name: abolished glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which glutathione gamma-glutamylcysteinyltransferase activity is absent." [PomBase:mah] synonym: "glutathione gamma-glutamylcysteinyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000754 ! abnormal glutathione gamma-glutamylcysteinyltransferase activity created_by: midori creation_date: 2014-07-08T14:16:15Z [Term] id: FYPO:0003506 name: normal growth on copper def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing copper ions." [PomBase:mah] synonym: "normal cell population growth in presence of copper" EXACT [PomBase:mah] synonym: "normal cell population growth on copper" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on copper ion" EXACT [PomBase:mah] synonym: "normal cellular response to copper" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on copper ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on copper" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-07-08T14:18:40Z [Term] id: FYPO:0003507 name: normal growth on zinc def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing zinc ions." [PomBase:mah] synonym: "normal cell population growth in presence of zinc" EXACT [PomBase:mah] synonym: "normal cell population growth on zinc" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on zinc ion" EXACT [PomBase:mah] synonym: "normal cellular response to zinc" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on zinc ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on zinc" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-07-08T14:25:47Z [Term] id: FYPO:0003508 name: normal growth on mercury def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mercury ions." [PomBase:mah] synonym: "normal cell population growth in presence of mercury" EXACT [PomBase:mah] synonym: "normal cell population growth on mercury" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on mercury ion" EXACT [PomBase:mah] synonym: "normal cellular response to mercury" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on mercury ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on mercury" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-07-08T14:26:47Z [Term] id: FYPO:0003509 name: normal growth on selenite ion def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing selenite ions." [PomBase:mah] synonym: "normal cell population growth in presence of selenite ion" EXACT [PomBase:mah] synonym: "normal cell population growth on selenite ion" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to selenite ion" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on selenite" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on selenite ion" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-07-08T14:27:40Z [Term] id: FYPO:0003510 name: normal growth on silver ions def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing silver ions." [PomBase:mah] synonym: "normal cell population growth in presence of silver ions" EXACT [PomBase:mah] synonym: "normal cell population growth on silver ions" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to silver ions" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on silver" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth on silver ions" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-07-08T14:28:44Z [Term] id: FYPO:0003511 name: L-ergothioneine absent from cell def: "A cell phenotype in which the amount of L-ergothioneine measured in a cell is too low to detect." [PomBase:mah] is_a: FYPO:0001888 ! substance absent from cell is_a: FYPO:0003521 ! decreased cellular L-ergothioneine level created_by: midori creation_date: 2014-07-08T14:33:51Z [Term] id: FYPO:0003512 name: hercynine absent from cell def: "A cell phenotype in which the amount of hercynine (N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine) measured in a cell is too low to detect." [PomBase:mah] synonym: "N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine absent from cell" EXACT [CHEBI:15781] is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2014-07-08T14:39:07Z [Term] id: FYPO:0003513 name: hercynylcysteine sulfoxide absent from cell def: "A cell phenotype in which the amount of hercynylcysteine sulfoxide measured in a cell is too low to detect." [PomBase:mah] synonym: "hercynylcysteine sulphoxide absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2014-07-08T14:40:26Z [Term] id: FYPO:0003514 name: hercynylselenocysteine absent from cell def: "A cell phenotype in which the amount of hercynylselenocysteine measured in a cell is too low to detect." [PomBase:mah] is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2014-07-08T14:41:09Z [Term] id: FYPO:0003515 name: L-selenoneine absent from cell def: "A cell phenotype in which the amount of L-selenoneine measured in a cell is too low to detect." [PomBase:mah] is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2014-07-08T14:41:39Z [Term] id: FYPO:0003516 name: increased cellular L-ergothioneine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ergothioneine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-ergothioneine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased L-ergothioneine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-07-08T14:42:37Z [Term] id: FYPO:0003517 name: increased cellular L-selenoneine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-selenoneine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-selenoneine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased L-selenoneine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-07-08T14:43:51Z [Term] id: FYPO:0003518 name: increased cellular hercynine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynine (N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular hercynine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine level" EXACT [CHEBI:15781] synonym: "increased cellular trimethyl-histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular trimethylhistidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased hercynine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-07-08T14:44:20Z [Term] id: FYPO:0003519 name: increased cellular hercynylcysteine sulfoxide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylcysteine sulfoxide measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular hercynylcysteine sulfoxide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular hercynylcysteine sulphoxide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased hercynylcysteine sulfoxide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-07-08T14:44:54Z [Term] id: FYPO:0003520 name: increased cellular hercynylselenocysteine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylselenocysteine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular hercynylselenocysteine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased hercynylselenocysteine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-07-08T14:45:15Z [Term] id: FYPO:0003521 name: decreased cellular L-ergothioneine level def: "A cell phenotype in which the amount of L-ergothioneine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-ergothioneine accumulation" RELATED [PomBase:mah] synonym: "decreased L-ergothioneine level" EXACT [PomBase:mah] synonym: "reduced cellular L-ergothioneine level" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2014-07-08T14:47:20Z [Term] id: FYPO:0003522 name: increased cellular hercynylcysteine sulfoxide level def: "A cell phenotype in which the amount of hercynylcysteine sulfoxide measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular hercynylcysteine sulphoxide level" EXACT [PomBase:mah] synonym: "increased hercynylcysteine sulfoxide level" EXACT [PomBase:mah] is_a: FYPO:0000990 ! increased level of substance in cell created_by: midori creation_date: 2014-07-08T14:54:15Z [Term] id: FYPO:0003523 name: increased cellular hercynylselenocysteine level def: "A cell phenotype in which the amount of hercynylselenocysteine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased hercynylselenocysteine level" EXACT [PomBase:mah] is_a: FYPO:0000990 ! increased level of substance in cell created_by: midori creation_date: 2014-07-08T14:58:41Z [Term] id: FYPO:0003524 name: abnormal actin cytoskeleton organization at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal at one or both cell tips." [GO:0030036, PMID:24954052, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton' (FYPO:0002398), but note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton organisation at cell tip" EXACT [PomBase:mah] synonym: "abnormal actin cytoskeleton organization at cell end" EXACT [PomBase:mah] synonym: "abnormal actin cytoskeleton organization at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cytoskeleton organization at cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2014-07-08T15:10:06Z [Term] id: FYPO:0003525 name: increased actin filament polymerization at cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the addition of actin monomers to a filament occurs to a greater extent than normal at one or both cell tips." [GO:0030041, PMID:24954052, PomBase:mah] synonym: "increased actin filament polymerisation at cell tip" EXACT [PomBase:mah] synonym: "increased actin filament polymerization at cell end" EXACT [PomBase:mah] synonym: "increased actin filament polymerization at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased actin filament polymerization at cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003524 ! abnormal actin cytoskeleton organization at cell tip created_by: midori creation_date: 2014-07-08T15:12:02Z [Term] id: FYPO:0003526 name: decreased actin filament-based movement def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament-based movement is decreased. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GO:0030048, PMID:24954052, PomBase:mah] synonym: "decreased actin filament-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased actin filament-based movement during vegetative growth" EXACT [PomBase:mah] synonym: "reduced actin filament-based movement" EXACT [PomBase:mah] is_a: FYPO:0005900 ! abnormal actin filament-based movement created_by: midori creation_date: 2014-07-08T15:15:23Z [Term] id: FYPO:0003527 name: protein mislocalized to cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the cell tip is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at the cell tip in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to cell tip" EXACT [PomBase:vw] synonym: "protein mislocalised to cell tip" EXACT [PomBase:mah] synonym: "protein mislocalised to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cell end" EXACT [PomBase:mah] synonym: "protein mislocalized to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2014-07-08T15:17:32Z [Term] id: FYPO:0003528 name: protein mislocalized to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the actomyosin contractile ring is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at the contractile ring in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to actomyosin contractile ring" EXACT [PomBase:vw] synonym: "protein mislocalised to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "protein mislocalised to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "protein mislocalized to mitotic contractile ring" EXACT [PomBase:vw] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2014-07-08T15:24:40Z [Term] id: FYPO:0003529 name: inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells def: "A phenotype in which a spore germinates to produce a cell that enters the cell cycle and undergoes two or more rounds of cell division, but then becomes elongated and undergoes cell cycle arrest in interphase of the mitotic cell cycle, and eventually dies." [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated aseptate cell" EXACT [PMID:15116432, PomBase:al, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated cell arrested at interphase" EXACT [PomBase:vw] synonym: "inviable germinated spore, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells" EXACT [PomBase:mah] is_a: FYPO:0002262 ! inviable after spore germination, multiple cell divisions, elongated cell created_by: midori creation_date: 2014-07-08T16:53:27Z [Term] id: FYPO:0003530 name: normal S-phase DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type). The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [PomBase:mah] synonym: "normal intra-S DNA damage checkpoint" EXACT [PomBase:mah] synonym: "normal mitotic S-phase DNA damage checkpoint" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint activation" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001705 ! normal mitotic DNA damage checkpoint created_by: midori creation_date: 2014-07-09T14:22:09Z [Term] id: FYPO:0003531 name: normal peroxisome size def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which peroxisome size is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal peroxisome size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal peroxisome size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-07-09T14:39:27Z [Term] id: FYPO:0003532 name: increased monopolar index def: "A cell population phenotype in which the monopolar index is higher than normal. The monopolar index is the proportion of the population undergoing monopolar growth at any given time." [PMID:20501954, PomBase:al, PomBase:mah] synonym: "increased frequency of monopolar growth polarity" RELATED [PMID:20501954] synonym: "increased number of cells undergoing monopolar growth" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype relationship: output_of FYPO:0003150 ! decreased NETO created_by: midori creation_date: 2014-07-09T15:01:21Z [Term] id: FYPO:0003533 name: increased bipolar index def: "A cell population phenotype in which the bipolar index is higher than normal. The bipolar index is the proportion of the population undergoing bipolar growth at any given time." [PMID:20501954, PomBase:al, PomBase:mah] synonym: "increased frequency of bipolar growth polarity" RELATED [PMID:20501954] synonym: "increased number of cells undergoing bipolar growth" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-07-09T15:03:49Z [Term] id: FYPO:0003534 name: decreased monopolar index def: "A cell population phenotype in which the monopolar index is lower than normal. The monopolar index is the proportion of the population undergoing monopolar growth at any given time." [PMID:20501954, PomBase:al, PomBase:mah] synonym: "decreased frequency of monopolar growth polarity" RELATED [PMID:20501954] synonym: "decreased number of cells undergoing monopolar growth" EXACT [PomBase:mah] synonym: "reduced monopolar index" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-07-09T15:24:42Z [Term] id: FYPO:0003535 name: decreased bipolar index def: "A cell population phenotype in which the bipolar index is lower than normal. The bipolar index is the proportion of the population undergoing bipolar growth at any given time." [PMID:20501954, PomBase:al, PomBase:mah] synonym: "decreased frequency of bipolar growth polarity" RELATED [PMID:20501954] synonym: "decreased number of cells undergoing bipolar growth" EXACT [PomBase:mah] synonym: "reduced bipolar index" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-07-09T15:25:04Z [Term] id: FYPO:0003536 name: increased septation index in stationary phase def: "A cell population phenotype in which the septation index is higher than normal in a population in stationary phase. The septation index is the proportion of the population undergoing septation at any given time." [PomBase:mah, PomBase:vw] synonym: "increased septation in stationary phase" RELATED [PomBase:mah] synonym: "increased septation index during stationary phase" EXACT [PomBase:mah] synonym: "septated in stationary phase" RELATED [PomBase:vw] is_a: FYPO:0000650 ! increased septation index created_by: midori creation_date: 2014-07-15T10:50:15Z [Term] id: FYPO:0003537 name: decreased rate of premeiotic DNA replication def: "A cellular process phenotype in which the rate, or speed, of premeiotic DNA replication is decreased." [PomBase:mah] synonym: "reduced rate of premeiotic DNA replication" EXACT [PomBase:mah] is_a: FYPO:0001981 ! decreased rate of DNA replication created_by: midori creation_date: 2014-07-15T10:58:05Z [Term] id: FYPO:0003538 name: premature meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division begins earlier than normal." [PomBase:mah] synonym: "advanced meiosis I" EXACT [PomBase:mah] synonym: "premature first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2014-07-15T10:59:35Z [Term] id: FYPO:0003539 name: decreased global homologous chromosome pairing def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) over the entire length of the chromosomes." [PomBase:mah] synonym: "decreased generalised homologous chromosome pairing" EXACT [PATO:0002403] synonym: "decreased global homologous chromosome pairing at meiosis" EXACT [GO:0007129] synonym: "decreased global synapsis" EXACT [GO:0007129] synonym: "globally decreased homologous chromosome pairing" EXACT [PomBase:mah] synonym: "reduced global homologous chromosome pairing" EXACT [PomBase:mah] is_a: FYPO:0003024 ! abnormal homologous chromosome pairing created_by: midori creation_date: 2014-07-15T12:46:12Z [Term] id: FYPO:0003540 name: decreased regional homologous chromosome pairing def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) in one or more specific regions of the chromosomes." [PomBase:mah] synonym: "decreased localised homologous chromosome pairing" EXACT [PATO:0000627] synonym: "decreased regional homologous chromosome pairing at meiosis" EXACT [GO:0007129] synonym: "decreased regional synapsis" EXACT [GO:0007129] synonym: "reduced regional homologous chromosome pairing" EXACT [PomBase:mah] synonym: "regionally decreased homologous chromosome pairing" EXACT [PomBase:mah] is_a: FYPO:0003024 ! abnormal homologous chromosome pairing created_by: midori creation_date: 2014-07-15T12:54:18Z [Term] id: FYPO:0003541 name: normal protein localization to meiotic spindle pole body def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to meiotic spindle pole body" EXACT [PomBase:mah] synonym: "normal protein localization to meiotic SPB" EXACT [PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis created_by: midori creation_date: 2014-07-15T13:05:03Z [Term] id: FYPO:0003542 name: abolished protein localization to meiotic spindle pole body def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Use this term for cells in which in which the re-accumulation of some spindle pole body components does not occur at the onset of meiosis I. synonym: "abolished protein localisation to meiotic spindle pole body" EXACT [PomBase:mah] synonym: "abolished protein localization to meiotic SPB" EXACT [PomBase:mah] synonym: "protein localization to meiotic spindle pole body abolished" EXACT [PomBase:mah] is_a: FYPO:0002771 ! abnormal protein localization to meiotic spindle pole body is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle created_by: midori creation_date: 2014-07-15T13:06:08Z [Term] id: FYPO:0003543 name: increased number of double-strand break sites def: "A cell phenotype in which the number of sites of double-strand breaks in DNA is greater than normal." [PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad52 foci' (FYPO:0004709). synonym: "accumulation of DNA damage foci" RELATED [PomBase:mah] synonym: "accumulation of double-strand break sites" EXACT [PomBase:mah] synonym: "increased number of DNA damage foci" RELATED [PomBase:mah] is_a: FYPO:0003546 ! increased DNA damage created_by: midori creation_date: 2014-07-15T13:31:59Z [Term] id: FYPO:0003544 name: increased number of double-strand break sites during meiotic cell cycle def: "A cell phenotype in which the number of sites of double-strand breaks in DNA is greater than normal during a meiotic cell cycle." [PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad52 foci' (FYPO:0004709). synonym: "accumulation of DNA damage foci during meiotic cell cycle" RELATED [PomBase:mah] synonym: "accumulation of double-strand break sites during meiotic cell cycle" EXACT [PomBase:mah] synonym: "increased number of DNA damage foci during meiotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of double-strand break sites during meiosis" RELATED [PomBase:mah] synonym: "increased number of meiotic double-strand break sites" EXACT [PomBase:vw] synonym: "increased number of meiotic double-strand breaks" EXACT [PomBase:vw] is_a: FYPO:0003543 ! increased number of double-strand break sites created_by: midori creation_date: 2014-07-15T13:33:04Z [Term] id: FYPO:0003545 name: increased duration of mitotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype in which the duration of mitotic cell cycle arrest or delay due to regulation by the DNA replication checkpoint is greater than normal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete." [PomBase:mah] synonym: "increased duration of DNA replication checkpoint" BROAD [PomBase:mah] synonym: "increased duration of mitotic cell cycle DNA replication checkpoint activation" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "mitotic cell cycle DNA replication checkpoint activated" RELATED [PomBase:mah] synonym: "prolonged mitotic cell cycle DNA replication checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000173 ! abnormal mitotic cell cycle DNA replication checkpoint created_by: midori creation_date: 2014-07-15T13:40:17Z [Term] id: FYPO:0003546 name: increased DNA damage def: "A cell phenotype in which the amount of DNA damage measured in a cell is greater than normal. The number, extent, or both of damage sites may be increased." [PomBase:mah] synonym: "increased number of DNA lesions" RELATED [PomBase:al] synonym: "increased spontaneous DNA lesions" RELATED [PomBase:vw] is_a: FYPO:0000136 ! cellular physical quality phenotype created_by: midori creation_date: 2014-07-15T13:46:05Z [Term] id: FYPO:0003547 name: increased DNA damage during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured in a cell is greater than normal. The number, extent, or both of damage sites may be increased." [PomBase:mah] synonym: "increased DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of DNA lesions during vegetative growth" RELATED [PomBase:al] synonym: "increased spontaneous DNA lesions during vegetative growth" RELATED [PomBase:vw] is_a: FYPO:0003546 ! increased DNA damage created_by: midori creation_date: 2014-07-15T13:58:24Z [Term] id: FYPO:0003548 name: abolished mitotic G1/S phase transition following nitrogen starvation-induced G1 phase arrest def: "A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle does not occur after the cell has been arrested in G1 phase due to nitrogen starvation. The cell remains arrested in G1." [PMID:9366254, PomBase:mah] comment: A G1/S delay may indicate that a checkpoint, such as the cell size checkpoint or the G1/S DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "abolished cell cycle progression through mitotic G1/S phase transition following cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished mitotic G1 phase progression following nitrogen starvation-induced G1 phase arrest" RELATED [PomBase:mah] synonym: "abolished mitotic G1/S transition following nitrogen starvation-induced G1 phase arrest" EXACT [PomBase:mah] synonym: "mitotic cell cycle G1/S phase transition abolished following nitrogen starvation-induced G1 phase arrest" EXACT [PomBase:mah] synonym: "mitotic G1/S phase transition abolished after recovery from nitrogen starvation-induced G1 arrest" EXACT [PMID:8657126, PomBase:vw] is_a: FYPO:0000394 ! abnormal mitotic G1/S phase transition created_by: midori creation_date: 2014-07-15T14:10:19Z [Term] id: FYPO:0003549 name: abnormal protein localization during meiosis def: "A cell phenotype that affects the localization of a protein in a cell during one or both meiotic nuclear divisions. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abnormal cellular protein localisation during meiosis" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization during meiosis" EXACT [PomBase:mah] synonym: "abnormal protein localisation during meiosis" EXACT [PomBase:mah] synonym: "abnormal protein localization during meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0004094 ! abnormal protein localization during meiotic cell cycle created_by: midori creation_date: 2014-07-17T09:54:27Z [Term] id: FYPO:0003550 name: decreased protein level during meiosis def: "A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during meiosis" RELATED [PomBase:mah] synonym: "decreased protein level during meiotic nuclear division" EXACT [GO:0140013] synonym: "reduced protein level during meiosis" EXACT [PomBase:mah] is_a: FYPO:0004991 ! decreased protein level during meiotic cell cycle created_by: midori creation_date: 2014-07-17T10:26:58Z [Term] id: FYPO:0003551 name: abnormal RNA catabolic process def: "A cellular process phenotype in which an RNA catabolic process is abnormal." [GO:0006401, PomBase:mah] synonym: "abnormal RNA breakdown" EXACT [PomBase:mah] synonym: "abnormal RNA catabolism" EXACT [GO:0006401] synonym: "abnormal RNA degradation" EXACT [PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2014-07-17T10:43:12Z [Term] id: FYPO:0003552 name: decreased RNA catabolic process def: "A cellular process phenotype in which the occurrence of an RNA catabolic process is decreased." [PomBase:mah] synonym: "decreased RNA breakdown" EXACT [PomBase:mah] synonym: "decreased RNA catabolism" EXACT [GO:0006401] synonym: "decreased RNA degradation" EXACT [PomBase:mah] synonym: "reduced RNA catabolic process" EXACT [PomBase:mah] is_a: FYPO:0003551 ! abnormal RNA catabolic process relationship: has_output FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2014-07-17T10:43:44Z [Term] id: FYPO:0003553 name: increased RNA catabolic process def: "A cellular process phenotype in which the occurrence of an RNA catabolic process is increased." [PomBase:mah] synonym: "increased RNA breakdown" EXACT [PomBase:mah] synonym: "increased RNA catabolism" EXACT [GO:0006401] synonym: "increased RNA degradation" EXACT [PomBase:mah] is_a: FYPO:0003551 ! abnormal RNA catabolic process relationship: has_output FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2014-07-17T10:43:48Z [Term] id: FYPO:0003554 name: increased degradation of middle meiotic gene mRNA during late meiosis def: "A cellular process phenotype in which the occurrence of degradation of RNA transcribed from middle meiotic genes is increased during late meiosis. Middle meiotic genes are normally transcribed during meiotic nuclear division." [PMID:20531409, PomBase:mah] synonym: "increased breakdown of middle meiotic gene mRNA during late meiosis" EXACT [PomBase:mah] synonym: "increased catabolism of middle meiotic gene mRNA during late meiosis" EXACT [PomBase:mah] synonym: "increased degradation of middle meiosis gene mRNA during late meiosis" EXACT [PomBase:mah] synonym: "increased degradation of middle meiotic gene mRNA during late meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased degradation of middle meiotic gene RNA during late meiosis" EXACT [PomBase:mah] is_a: FYPO:0003553 ! increased RNA catabolic process created_by: midori creation_date: 2014-07-17T10:48:30Z [Term] id: FYPO:0003555 name: normal chromatin silencing at subtelomere def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing in subtelomeric regions is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "normal chromatin silencing at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromatin silencing at telomere" RELATED [PomBase:mah] is_a: FYPO:0002335 ! normal chromatin silencing created_by: midori creation_date: 2014-07-17T10:53:27Z [Term] id: FYPO:0003556 name: abnormal transcription termination def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription from a DNA template is abnormal." [GO:0006353, PomBase:mah] synonym: "abnormal DNA-templated transcription, termination" EXACT [GO:0006353] synonym: "abnormal termination of transcription" EXACT [PomBase:al] synonym: "abnormal transcription termination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal transcription termination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth is_a: FYPO:0004851 ! abnormal RNA metabolic process created_by: midori creation_date: 2014-07-17T11:10:03Z [Term] id: FYPO:0003557 name: increased antisense RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell is higher than normal. Antisense RNA is transcribed from the coding, rather than the template, strand of DNA." [PomBase:mah, SO:0000644] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased antisense RNA accumulation" RELATED [PomBase:mah] synonym: "increased antisense RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased antisense RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased antisense RNA transcript level" EXACT [PomBase:vw] synonym: "increased level of antisense transcripts" EXACT [PomBase:al] is_a: FYPO:0005857 ! altered antisense RNA level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2014-07-17T11:14:47Z [Term] id: FYPO:0003558 name: increased repeat element RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from repeat elements, such as LTRs, retrotransposons, or wtf elements, measured in a cell is higher than normal." [PMID:24957674, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. Also consider using a more specific term to annotate each phenotype. synonym: "increased repeat element RNA accumulation" RELATED [PomBase:mah] synonym: "increased repeat element RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased repeat element RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased repeat element transcript level" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2014-07-17T11:26:36Z [Term] id: FYPO:0003559 name: sensitive to doxorubicin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to doxorubicin. Cells stop growing (and may die) at a concentration of doxorubicin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to doxorubicin" EXACT [PomBase:mah] synonym: "sensitive to doxorubicin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to doxorubicin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-07-17T14:35:50Z [Term] id: FYPO:0003560 name: abnormal spindle pole body organization def: "A cell phenotype in which spindle pole body organization is abnormal. Spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB)." [GO:0051300, PomBase:mah] synonym: "abnormal SPB organization" EXACT [PomBase:mah] synonym: "abnormal spindle pole body organisation" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2014-07-17T14:39:15Z [Term] id: FYPO:0003561 name: abnormal prospore-specific spindle pole body remodeling def: "A cell phenotype in which prospore-specific spindle pole body remodeling is abnormal. Prospore-specific spindle pole body remodeling takes place during the second meiotic nuclear division during ascospore formation and results in the structural reorganization of the SPB, including the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP)." [GO:001322, PomBase:mah] synonym: "abnormal ascospore-type prospore-specific spindle pole body remodeling" EXACT [GO:0031322] synonym: "abnormal forespore-specific spindle pole body remodeling" EXACT [PomBase:mah] synonym: "abnormal prospore-specific SPB remodeling" EXACT [PomBase:mah] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2014-07-17T14:41:46Z [Term] id: FYPO:0003562 name: normal horsetail nucleus morphology def: "A physical cellular phenotype in which the size, shape, or structure of the horsetail nucleus is normal (i.e. indistinguishable from wild type). The horsetail nucleus forms during the rapid oscillatory movement at meiotic prophase I." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. Consider also annotating to 'normal horsetail movement' (FYPO:0003835). synonym: "normal horsetail nuclear morphology" EXACT [PomBase:mah] is_a: FYPO:0001673 ! normal nuclear morphology created_by: midori creation_date: 2014-07-17T15:14:25Z [Term] id: FYPO:0003563 name: normal meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal first meiotic nuclear division" EXACT [GO:0007127] synonym: "normal meiosis I progression" EXACT [PomBase:vw] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-07-17T15:15:34Z [Term] id: FYPO:0003564 name: abnormal meiotic DNA double-strand break formation def: "A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is abnormal." [GO:0042138, PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2014-07-17T15:16:48Z [Term] id: FYPO:0003565 name: increased protein phosphorylation during meiosis I def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during first meiotic nuclear division" EXACT [PomBase:vw] is_a: FYPO:0002680 ! increased protein phosphorylation is_a: FYPO:0006765 ! abnormal protein phosphorylation during meiotic cell cycle created_by: midori creation_date: 2014-07-17T15:17:53Z [Term] id: FYPO:0003566 name: delayed onset of mitotic spindle pole body separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body separation begins later than normal." [PomBase:mah] synonym: "delayed mitotic spindle pole body separation" EXACT [PomBase:mah] synonym: "delayed onset of mitotic SPB separation" EXACT [PomBase:mah] synonym: "delayed onset of spindle pole body separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic spindle pole body separation delayed during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001733 ! abnormal mitotic spindle pole body separation created_by: midori creation_date: 2014-07-17T15:49:09Z [Term] id: FYPO:0003567 name: abnormal mitotic spindle pole body insertion into nuclear envelope alt_id: FYPO:0006595 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of the mitotic spindle pole body localization into the nuclear envelope is abnormal." [GO:0140480, PMID:19942852, PMID:24963130, PomBase:mah] synonym: "abnormal establishment of spindle pole body localization to nuclear envelope" EXACT [GO:0140480, PomBase:mah, PomBase:vw] synonym: "abnormal mitotic SPB insertion into nuclear envelope" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body insertion into nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body localization to nuclear envelope" RELATED [PomBase:mah] synonym: "abnormal spindle pole body insertion into nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000534 ! abnormal mitotic spindle pole body localization created_by: midori creation_date: 2014-07-17T16:57:31Z [Term] id: FYPO:0003568 name: abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of a spindle pole body (SPB) into the nuclear envelope is abnormal, and the SPB enters the nucleus. An open fenestra remains present in the nuclear envelope." [PMID:24963130, PomBase:mah] synonym: "abnormal establishment of mitotic spindle pole body localization to nuclear envelope, with spindle pole body in nucleoplasm" EXACT [PomBase:vw] synonym: "abnormal mitotic SPB insertion into nuclear envelope, with spindle pole body in nucleoplasm" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "SPB unanchored to nuclear envelope" RELATED [PomBase:mah] synonym: "spindle pole body in nucleoplasm, unanchored to nuclear envelope" RELATED [PomBase:mah] synonym: "spindle pole body unanchored to nuclear envelope" RELATED [PomBase:mah] synonym: "unanchored spindle pole bodies" RELATED [PomBase:vw] is_a: FYPO:0003567 ! abnormal mitotic spindle pole body insertion into nuclear envelope created_by: midori creation_date: 2014-07-17T17:01:29Z [Term] id: FYPO:0003569 name: abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in cytoplasm def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of a spindle pole body (SPB) into the nuclear envelope is abnormal, and the SPB enters the cytoplasm. An open fenestra remains present in the nuclear envelope." [PMID:24963130, PomBase:mah] synonym: "abnormal establishment of mitotic spindle pole body localization to nuclear envelope, with spindle pole body in cytoplasm" EXACT [PomBase:vw] synonym: "abnormal mitotic SPB insertion into nuclear envelope, with spindle pole body in cytoplasm" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "SPB unanchored to nuclear envelope" RELATED [PomBase:mah] synonym: "spindle pole body in cytoplasm, unanchored to nuclear envelope" RELATED [PomBase:mah] synonym: "spindle pole body unanchored to nuclear envelope" RELATED [PomBase:mah] synonym: "unanchored spindle pole bodies" RELATED [PomBase:vw] is_a: FYPO:0003567 ! abnormal mitotic spindle pole body insertion into nuclear envelope created_by: midori creation_date: 2014-07-17T17:03:47Z [Term] id: FYPO:0003570 name: normal attachment of spindle microtubules to kinetochore def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2014-07-23T16:52:09Z [Term] id: FYPO:0003571 name: decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin at the silenced mating-type cassettes occurs to a lower extent than normal." [PMID:18761674, PomBase:mah] synonym: "decreased histone H3 K9 methylation at silent mating-type cassette during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 methylation at silent mating locus during vegetative growth" EXACT [PomBase:al] synonym: "decreased histone H3-K9 methylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9me at silent mating-type cassette during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation at silent mating-type cassette during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-07-22T11:45:07Z [Term] id: FYPO:0003572 name: decreased histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a lower extent than normal." [PMID:18761674, PomBase:mah] synonym: "decreased histone H3 K9 methylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation at subtelomeres during vegetative growth" EXACT [PomBase:al] synonym: "decreased histone H3-K9 methylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 methylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "decreased histone H3K9me at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-07-22T11:55:29Z [Term] id: FYPO:0003573 name: decreased protein localization to heterochromatin at silent mating-type cassette def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to heterochromatin at silent mating-type cassette" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at mating-type region" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to heterochromatin at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "decreased protein localization to silent mating type heterochromatin" EXACT [PomBase:al] synonym: "reduced protein localization to heterochromatin at silent mating-type cassette" EXACT [PomBase:mah] is_a: FYPO:0002385 ! decreased protein localization to heterochromatin during vegetative growth created_by: midori creation_date: 2014-07-22T12:01:04Z [Term] id: FYPO:0003574 name: normal histone H3-K14 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K14 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K14 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K14 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K14 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3-K14 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3K14 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0003224 ! normal histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2014-07-22T12:05:26Z [Term] id: FYPO:0003575 name: normal histone H3-K9 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere outer repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3-K9 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3K9 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0043970] is_a: FYPO:0003223 ! normal histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2014-07-22T12:07:12Z [Term] id: FYPO:0003576 name: normal protein localization to subtelomeric heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin in subtelomeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to subtelomeric heterochromatin" EXACT [PomBase:mah] synonym: "normal protein localization to subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to telomeric heterochromatin" RELATED [PomBase:mah, PomBase:vw] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-07-22T12:15:47Z [Term] id: FYPO:0003577 name: abolished plasma membrane to vacuole transport after nitrogen starvation def: "A cellular process phenotype in which the transport of a substance from the plasma membrane to the vacuole does not occur when the cell is subject to, or recovering from, nitrogen starvation. Transport normally occurs in two stages, plasma membrane to endosome followed by endosome to vacuole transport." [PMID:22194353, PomBase:mah] comment: This term can be used to annotate phenotypes in which a protein that normally appears at the plasma membrane transiently during nitrogen starvation is not subsequently transported to the vacuole. It can also be used for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "abolished plasma membrane to vacuole protein transport after nitrogen starvation" NARROW [PomBase:mah] is_a: FYPO:0003578 ! abnormal vacuolar transport created_by: midori creation_date: 2014-07-22T12:35:29Z [Term] id: FYPO:0003578 name: abnormal vacuolar transport def: "A cellular process phenotype in which vacuolar transport is abnormal." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) to or from the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "vacuolar transport: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2014-07-22T12:52:21Z [Term] id: FYPO:0003579 name: normal RNA level during meiosis def: "A cell phenotype in which the amount of RNA measured in a cell during one or both meiotic nuclear divisions is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal cellular RNA level during meiosis" EXACT [PomBase:mah] synonym: "normal mRNA level during meiosis" NARROW [PomBase:mah] synonym: "normal RNA accumulation during meiosis" RELATED [PomBase:mah] synonym: "normal RNA level during meiotic nuclear division" EXACT [GO:0140013] synonym: "normal transcript level during meiosis" EXACT [PomBase:mah] is_a: FYPO:0006976 ! normal RNA level during meiotic cell cycle created_by: midori creation_date: 2014-07-22T13:51:14Z [Term] id: FYPO:0003580 name: increased number of Sad1 foci during response to DNA damage def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Sad1 accumulates is greater than normal during a cellular response to DNA damage." [PMID:24943839, PomBase:mah] comment: Sad1 is normally located at the spindle pole body, but during a response to DNA damage, Sad1 foci associated with double-strand breaks appear. synonym: "increased number of Sad1 foci during DNA damage response" EXACT [PomBase:vw] synonym: "increased number of Sad1 foci during response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Sad1 foci during response to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2014-07-22T14:27:55Z [Term] id: FYPO:0003581 name: increased number of Kms1 foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Kms1 accumulates is greater than normal." [PMID:24943839, PomBase:mah] synonym: "increased number of Kms1 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Kms1 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2014-07-22T14:31:04Z [Term] id: FYPO:0003582 name: increased number of Kms1 foci during response to DNA damage def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Kms1 accumulates is greater than normal during a cellular response to DNA damage." [PMID:24943839, PomBase:mah] synonym: "increased number of Kms1 foci during DNA damage response" EXACT [PomBase:vw] synonym: "increased number of Kms1 foci during response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Kms1 foci during response to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003581 ! increased number of Kms1 foci created_by: midori creation_date: 2014-07-22T14:32:13Z [Term] id: FYPO:0003583 name: increased rate of Sad1 focus formation during response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of formation of foci containing the protein Sad1 is increased during a cellular response to DNA damage." [PMID:24943839, PomBase:mah] synonym: "increased rate of accumulation of Sad1 foci during DNA damage response" EXACT [PomBase:vw] synonym: "increased rate of Sad1 focus formation during response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of Sad1 focus formation during response to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2014-07-22T14:36:20Z [Term] id: FYPO:0003584 name: increased double-strand break repair via nonhomologous end joining def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is increased. NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity." [GO:0006303, PomBase:mah] synonym: "increased double-strand break repair via nonhomologous end joining during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased double-strand break repair via nonhomologous end joining during vegetative growth" EXACT [PomBase:mah] synonym: "increased NHEJ" EXACT [GO:0006303] synonym: "increased nonhomologous end joining" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2014-07-22T14:39:47Z [Term] id: FYPO:0003585 name: decreased anaphase-promoting complex-dependent protein catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome, is decreased." [GO:0031145, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process" EXACT [GO:0031145, PomBase:mah] synonym: "decreased anaphase-promoting complex-dependent protein catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased anaphase-promoting complex-dependent protein catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "decreased anaphase-promoting complex-dependent protein degradation" EXACT [GO:0031145, PomBase:mah] synonym: "reduced anaphase-promoting complex-dependent protein catabolic process" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth is_a: FYPO:0002797 ! decreased protein degradation created_by: midori creation_date: 2014-07-22T14:51:20Z [Term] id: FYPO:0003586 name: abnormal replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing is abnormal. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted." [GO:0031297, PomBase:mah] synonym: "abnormal collapsed replication fork processing" EXACT [GO:0031297] synonym: "abnormal HR-mediated fork restart" RELATED [PomBase:vw] synonym: "abnormal recovery from replication fork arrest" EXACT [GO:0031297] synonym: "abnormal recovery from replication fork stalling" EXACT [GO:0031297] synonym: "abnormal replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal replication fork restart" RELATED [GO:0031297] synonym: "abnormal replication restart" RELATED [GO:0031297] is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-07-22T14:54:31Z [Term] id: FYPO:0003587 name: loss of gross chromosomal rearrangement during replication fork processing def: "A cell phenotype in which the increase in gross chromosomal rearrangements that normally results from processing arrested replication forks is diminished or abolished." [PMID:23093942, PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2014-07-22T14:59:24Z [Term] id: FYPO:0003588 name: increased gross chromosomal rearrangement during replication fork processing def: "A cell phenotype in which the increase in gross chromosomal rearrangements that normally results from processing arrested replication forks is enhanced, i.e. the incidence of rearrangement increases more than in wild type when an arrested fork is processed." [PMID:23093942, PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2014-07-22T15:00:00Z [Term] id: FYPO:0003589 name: decreased replication slippage during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications (\"replication slippage\") that normally results from processing arrested replication forks is diminished or abolished." [PMID:23093942, PomBase:mah] synonym: "decreased replication slippage during replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication slippage during replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "reduced replication slippage during replication fork processing" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2014-07-22T15:00:17Z [Term] id: FYPO:0003590 name: small vacuoles during sporulation def: "A cell phenotype in which vacuoles are smaller than normal during sporulation." [PomBase:mah] synonym: "vacuoles present in increased numbers, with decreased vacuole size, during sporulation" EXACT [PomBase:vw] is_a: FYPO:0002787 ! small vacuoles created_by: midori creation_date: 2014-07-22T15:12:40Z [Term] id: FYPO:0003591 name: abnormal protein complex binding def: "A molecular function phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a protein complex that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2014-07-23T16:54:48Z [Term] id: FYPO:0003592 name: increased anaphase-promoting complex binding def: "A molecular function phenotype in which the binding of one protein to the anaphase-promoting complex (APC) occurs to a greater extent than normal. The protein whose binding to the APC may be encoded by the mutated gene, or may be encoded by a different gene." [PomBase:mah] comment: This term can be used for any interaction with the APC that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0001571 ! increased protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2014-07-23T16:56:15Z [Term] id: FYPO:0003593 name: abolished anaphase-promoting complex-dependent protein catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome, is abolished." [GO:0031145, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process" EXACT [GO:0031145, PomBase:mah] synonym: "abolished anaphase-promoting complex-dependent protein catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished anaphase-promoting complex-dependent protein catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "abolished anaphase-promoting complex-dependent protein degradation" EXACT [GO:0031145, PomBase:mah] synonym: "anaphase-promoting complex-dependent protein catabolic process abolished" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0003585 ! decreased anaphase-promoting complex-dependent protein catabolic process created_by: midori creation_date: 2014-07-23T16:58:29Z [Term] id: FYPO:0003594 name: normal anaphase-promoting complex-dependent protein catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process" EXACT [GO:0031145, PomBase:mah] synonym: "normal anaphase-promoting complex-dependent protein catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal anaphase-promoting complex-dependent protein catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "normal anaphase-promoting complex-dependent protein degradation" EXACT [GO:0031145, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-07-23T17:00:08Z [Term] id: FYPO:0003595 name: S-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in a shape that consists of two curves in opposite directions." [PomBase:mah] synonym: "kinked cell" EXACT [PomBase:mah] synonym: "kinky cell" EXACT [PomBase:mah] synonym: "S-shaped vegetative cell" EXACT [PomBase:mah] synonym: "sigmoid cell" EXACT [PomBase:mah] synonym: "Z-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2014-07-29T14:55:16Z [Term] id: FYPO:0003596 name: abnormal snRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is abnormal." [GO:0034472, PomBase:mah] synonym: "abnormal snRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal snRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007918 ! abnormal RNA 3'-end processing created_by: midori creation_date: 2014-07-29T15:15:29Z [Term] id: FYPO:0003597 name: abolished snRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is abolished." [GO:0034472, PomBase:mah] synonym: "abolished snRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished snRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] synonym: "snRNA 3'-end processing abolished" EXACT [PomBase:mah] is_a: FYPO:0003596 ! abnormal snRNA 3'-end processing created_by: midori creation_date: 2014-07-29T15:17:08Z [Term] id: FYPO:0003598 name: decreased snRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is decreased." [GO:0034472, PomBase:mah] synonym: "decreased snRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased snRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] synonym: "reduced snRNA 3'-end processing" EXACT [PomBase:mah] is_a: FYPO:0003596 ! abnormal snRNA 3'-end processing created_by: midori creation_date: 2014-07-29T15:17:54Z [Term] id: FYPO:0003599 name: normal snRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is normal (i.e. indistinguishable from wild type)." [GO:0034472, PomBase:mah] synonym: "normal snRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal snRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-07-29T15:18:15Z [Term] id: FYPO:0003600 name: increased rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any rRNA precursor measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased rRNA precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0005996 ! altered rRNA or precursor level is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2014-07-29T15:21:16Z [Term] id: FYPO:0003601 name: decreased rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any rRNA precursor measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "decreased rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rRNA precursor transcript level" EXACT [PomBase:vw] synonym: "reduced rRNA precursor level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-07-29T15:22:13Z [Term] id: FYPO:0003602 name: abolished mRNA splicing, via spliceosome def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is abolished." [PMID:24298023, PomBase:mah] synonym: "abolished mRNA splicing, via spliceosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] synonym: "abolished nuclear mRNA splicing, via spliceosome" EXACT [PomBase:mah] synonym: "abolished splicing" BROAD [PomBase:al] synonym: "mRNA splicing via spliceosome abolished" EXACT [PomBase:mah] is_a: FYPO:0000189 ! abnormal mRNA splicing, via spliceosome created_by: midori creation_date: 2014-07-29T15:26:02Z [Term] id: FYPO:0003603 name: abnormal meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division is abnormal." [PomBase:mah] synonym: "abnormal first meiotic nuclear division" EXACT [GO:0007127] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2014-07-29T16:05:41Z [Term] id: FYPO:0003604 name: obsolete sister chromatid separation during meiosis I comment: equivalent to equational sister chromatid separation during meiosis I comment: OBSOLETE Sister chromatids may separate in meiosis I due to problems with either cohesion or kinetochore attachment to microtubules. Therefore consider also annotating to 'abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation' (FYPO:0000209), 'decreased meiotic sister chromatid cohesion' (FYPO:0002093), or 'merotelic kinetochore attachment during meiosis I' (FYPO:0005638). property_value: seeAlso FYPO:0005634 is_obsolete: true [Term] id: FYPO:0003606 name: decreased duration of meiotic prophase I def: "A cellular process phenotype in which the duration of prophase of the first meiotic nuclear division is shorter than normal." [PomBase:mah] synonym: "reduced duration of meiotic prophase I" EXACT [PomBase:mah] synonym: "short meiotic prophase I" EXACT [PomBase:al] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2014-07-29T16:21:25Z [Term] id: FYPO:0003607 name: abnormal spindle morphology def: "A physical cellular phenotype in which the size, shape, or structure of the mitotic or meiotic spindle is abnormal." [PomBase:mah] synonym: "spindle morphology: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000120 ! abnormal spindle created_by: midori creation_date: 2014-07-30T15:30:35Z [Term] id: FYPO:0003608 name: abnormal dehydrodolichyl diphosphate synthase activity def: "A molecular function phenotype in which the observed rate of dehydrodolichyl diphosphate synthase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-07-31T17:22:13Z [Term] id: FYPO:0003609 name: decreased dehydrodolichyl diphosphate synthase activity def: "A molecular function phenotype in which the observed rate of dehydrodolichyl diphosphate synthase activity is decreased." [PomBase:mah] synonym: "reduced dehydrodolichyl diphosphate synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003608 ! abnormal dehydrodolichyl diphosphate synthase activity created_by: midori creation_date: 2014-07-31T17:22:21Z [Term] id: FYPO:0003610 name: branched, elongated cell with branch forming adjacent to septum def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and a branch forms adjacent to an existing septum." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "branched, elongated cell with branch forming adjacent to septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched, elongated cell with branch forming adjacent to septum during vegetative growth" EXACT [PomBase:mah] synonym: "branched, elongated vegetative cell with branch forming adjacent to septum" EXACT [PomBase:mah] is_a: FYPO:0002459 ! viable branched, elongated vegetative cell created_by: midori creation_date: 2014-08-06T10:44:06Z [Term] id: FYPO:0003611 name: increased protein level during meiosis def: "A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during meiosis" RELATED [PomBase:mah] synonym: "increased protein level during meiotic nuclear division" EXACT [PomBase:vw] is_a: FYPO:0000836 ! increased protein level created_by: midori creation_date: 2014-08-06T11:36:40Z [Term] id: FYPO:0003612 name: viable spore population def: "A cell population phenotype in which cells in a population of spores are viable." [PomBase:mah] synonym: "viable population of spores" EXACT [PomBase:vw] is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2014-08-06T11:38:17Z [Term] id: FYPO:0003613 name: normal meiotic sister chromatid cohesion during meiotic prophase I def: "A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) during prophase of the first meiotic nuclear division." [PomBase:mah] synonym: "normal sister chromatid cohesion during meiotic prophase I" EXACT [PomBase:mah] is_a: FYPO:0002094 ! normal meiotic sister chromatid cohesion created_by: midori creation_date: 2014-08-06T11:39:43Z [Term] id: FYPO:0003614 name: meiotic spindle absent from cell during meiosis II def: "A cell phenotype in which the cell does not contain a detectable meiotic spindle during the second meiotic nuclear division." [PomBase:mah] synonym: "absent meiotic spindle during meiosis II" EXACT [PomBase:mah] synonym: "meiosis II spindle absent" EXACT [PomBase:al] synonym: "meiotic spindle absent from cell during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0006391 ! meiotic spindle absent from cell during meiosis created_by: midori creation_date: 2014-08-06T11:41:57Z [Term] id: FYPO:0003615 name: decreased meiotic DNA double-strand break formation def: "A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is decreased." [GO:0042138, PomBase:mah] synonym: "reduced meiotic DNA double-strand break formation" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2014-08-06T11:45:30Z [Term] id: FYPO:0003616 name: sensitive to fluphenazine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fluphenazine. Cells stop growing (and may die) at a concentration of fluphenazine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to fluphenazine" EXACT [PomBase:mah] synonym: "sensitive to fluphenazine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to fluphenazine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-06T11:57:20Z [Term] id: FYPO:0003617 name: sensitive to cytochalasin D def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cytochalasin D. Cells stop growing (and may die) at a concentration of cytochalasin D that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cytochalasin D" EXACT [PomBase:mah] synonym: "sensitive to cytochalasin D during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cytochalasin D during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-06T11:58:04Z [Term] id: FYPO:0003618 name: normal growth on aculeacin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing aculeacin A." [PomBase:mah] synonym: "normal cell population growth in presence of aculeacin A" EXACT [PomBase:mah] synonym: "normal cell population growth on aculeacin A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to aculeacin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on aculeacin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-06T11:58:44Z [Term] id: FYPO:0003619 name: normal mRNA splicing, via spliceosome def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mRNA splicing, via spliceosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear mRNA splicing, via spliceosome" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-08-06T12:06:30Z [Term] id: FYPO:0003620 name: normal pre-mRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal pre-mRNA accumulation" RELATED [PomBase:mah] synonym: "normal pre-mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal pre-mRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal pre-mRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2014-08-06T12:22:26Z [Term] id: FYPO:0003621 name: abolished U6 2'-O-snRNA methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule is abolished." [GO:1990438, PomBase:mah] synonym: "abolished U6 2'-O-snRNA methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "U6 2'-O-snRNA methylation abolished" EXACT [GO:0036261, PomBase:mah] synonym: "U6 2'-O-snRNA methylation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000371 ! abolished RNA modification is_a: FYPO:0008111 ! abnormal snRNA modification created_by: midori creation_date: 2014-08-06T12:24:59Z [Term] id: FYPO:0003622 name: abolished U6 2'-O-snRNA methylation at residue A41 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of the adenine residue at position 41 in an U6 snRNA molecule is abolished." [GO:1990438, PomBase:mah] synonym: "abolished U6 2'-O-snRNA methylation at residue A41 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished U6 A41 2'-O-snRNA methylation" EXACT [PomBase:mah] synonym: "U6 2'-O-snRNA methylation abolished at residue A41 during vegetative growth" EXACT [PomBase:mah] synonym: "U6 2'-O-snRNA methylation at residue A41 abolished" EXACT [GO:0036261, PomBase:mah] is_a: FYPO:0003621 ! abolished U6 2'-O-snRNA methylation created_by: midori creation_date: 2014-08-06T12:26:38Z [Term] id: FYPO:0003623 name: obsolete normal protein threonine phosphorylation during cellular response to heat def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to heat." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "normal protein threonine phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein threonine phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004154 created_by: midori creation_date: 2014-08-06T12:48:30Z [Term] id: FYPO:0003624 name: obsolete decreased protein threonine phosphorylation during cellular response to heat def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues of one or more specific proteins is decreased during a cellular response to heat." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased protein threonine phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein threonine phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein threonine phosphorylation during cellular response to heat" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004173 created_by: midori creation_date: 2014-08-06T12:50:27Z [Term] id: FYPO:0003625 name: abnormal microtubule cytoskeleton morphology during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the microtubule cytoskeleton is abnormal during interphase of the mitotic cell cycle." [PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. synonym: "abnormal microtubule cytoskeleton morphology during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal microtubule cytoskeleton morphology during mitotic interphase during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth created_by: midori creation_date: 2014-08-06T14:08:42Z [Term] id: FYPO:0003626 name: normal protein localization to shmoo tip def: "A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to shmoo tip" EXACT [PomBase:mah] synonym: "normal protein localization to mating projection tip" EXACT [PomBase:mah] synonym: "normal protein localization to shmoo projection" EXACT [PomBase:al] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2014-08-06T14:22:08Z [Term] id: FYPO:0003627 name: normal protein localization def: "A cell phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend using a more specific term if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "normal cellular protein localisation" EXACT [PomBase:mah] synonym: "normal cellular protein localization" EXACT [PomBase:mah] synonym: "normal protein localisation" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0002333 ! protein localization phenotype created_by: midori creation_date: 2014-08-06T14:23:40Z [Term] id: FYPO:0003628 name: abnormal ribonucleoprotein complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of ribonucleoprotein complex assembly is abnormal." [PomBase:mah] synonym: "abnormal protein-RNA complex assembly" EXACT [GO:0022618] synonym: "abnormal ribonucleoprotein complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ribonucleoprotein complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNA-protein complex assembly" EXACT [GO:0022618] synonym: "abnormal RNP complex assembly" EXACT [GO:0022618] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2014-08-06T14:31:10Z [Term] id: FYPO:0003629 name: abolished U2/U5/U6 snRNP complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spliceosomal tri-snRNP complex assembly is abolished." [PMID:12374752, PomBase:mah] synonym: "abolished U2/U5/U6 snRNP complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished U2/U5/U6 snRNP complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished U2/U5/U6 tri-snRNP complex assembly abolished" EXACT [PomBase:mah] synonym: "U2/U5/U6 snRNP complex assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0003628 ! abnormal ribonucleoprotein complex assembly created_by: midori creation_date: 2014-08-06T14:37:22Z [Term] id: FYPO:0003630 name: abolished U2-type prespliceosome assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which U2-type prespliceosome assembly is abolished. The U2-type prespliceosome is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP, and also contains other proteins." [GO:0071004, GO:1903241, PomBase:mah] synonym: "abolished U2-type prespliceosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished U2-type prespliceosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "U2-type prespliceosome assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0003628 ! abnormal ribonucleoprotein complex assembly created_by: midori creation_date: 2014-08-06T14:42:01Z [Term] id: FYPO:0003631 name: decreased U2-type prespliceosome assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which U2-type prespliceosome assembly is decreased. The U2-type prespliceosome is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP, and also contains other proteins." [GO:0071004, GO:1903241, PomBase:mah] synonym: "decreased U2-type prespliceosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased U2-type prespliceosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced U2-type prespliceosome assembly" EXACT [PomBase:mah] is_a: FYPO:0003628 ! abnormal ribonucleoprotein complex assembly created_by: midori creation_date: 2014-08-06T14:44:02Z [Term] id: FYPO:0003632 name: abnormal ribonucleoprotein complex binding def: "A molecular function phenotype in which the binding of one gene product (RNA or protein) to a ribonucleoprotein complex is abnormal. The gene product whose binding to the ribonucleoprotein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a ribonucleoprotein complex that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal RNP binding" EXACT [GO:0043021] is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2014-08-06T14:51:18Z [Term] id: FYPO:0003633 name: abolished U1 snRNP binding def: "A molecular function phenotype in which U1 snRNP binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a U1 snRNP that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "U1 snRNP binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003632 ! abnormal ribonucleoprotein complex binding created_by: midori creation_date: 2014-08-06T14:53:27Z [Term] id: FYPO:0003634 name: decreased U1 snRNP binding def: "A molecular function phenotype in which U1 snRNP binding by a gene product is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a U2 snRNP that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "reduced U1 snRNP binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0003632 ! abnormal ribonucleoprotein complex binding created_by: midori creation_date: 2014-08-06T14:55:01Z [Term] id: FYPO:0003635 name: abolished U2 snRNP binding def: "A molecular function phenotype in which U2 snRNP binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a U2 snRNP that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "U2 snRNP binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003632 ! abnormal ribonucleoprotein complex binding created_by: midori creation_date: 2014-08-06T14:55:20Z [Term] id: FYPO:0003636 name: decreased U2 snRNP binding def: "A molecular function phenotype in which U2 snRNP binding by a gene product is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a U2 snRNP that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "reduced U2 snRNP binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0003632 ! abnormal ribonucleoprotein complex binding created_by: midori creation_date: 2014-08-06T14:55:37Z [Term] id: FYPO:0003637 name: abnormal ADP binding def: "A molecular function phenotype in which occurrence of ADP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds ADP differently from wild type, or that a mutation in one gene affects ADP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-08-06T15:04:17Z [Term] id: FYPO:0003638 name: increased ADP binding def: "A molecular function phenotype in which occurrence of ADP binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds ADP more than wild type, or that a mutation in one gene increases ADP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0003637 ! abnormal ADP binding created_by: midori creation_date: 2014-08-06T15:04:22Z [Term] id: FYPO:0003639 name: abolished cell wall biogenesis def: "A cellular process phenotype in which cell wall biogenesis is abolished." [PomBase:mah] synonym: "abolished fungal-type cell wall biogenesis" EXACT [GO:0009272, PomBase:mah] synonym: "fungal-type cell wall biogenesis abolished" EXACT [PomBase:mah] is_a: FYPO:0000174 ! abnormal cell wall biogenesis created_by: midori creation_date: 2014-08-06T15:28:10Z [Term] id: FYPO:0003640 name: abnormal adenylate kinase activity def: "A molecular function phenotype in which the observed rate of adenylate kinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-06T15:31:08Z [Term] id: FYPO:0003641 name: increased adenylate kinase activity def: "A molecular function phenotype in which the observed rate of adenylate kinase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003640 ! abnormal adenylate kinase activity created_by: midori creation_date: 2014-08-06T15:31:12Z [Term] id: FYPO:0003642 name: abnormal urease activity def: "A molecular function phenotype in which the observed rate of urease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-06T15:33:13Z [Term] id: FYPO:0003643 name: decreased urease activity def: "A molecular function phenotype in which the observed rate of urease activity is decreased." [PomBase:mah] synonym: "reduced urease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003642 ! abnormal urease activity created_by: midori creation_date: 2014-08-06T15:33:18Z [Term] id: FYPO:0003644 name: RNA absent from cell during cellular response to thiamine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to thiamine starvation. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "RNA absent from cell during cellular response to thiamine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA absent from cell during cellular response to thiamine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "RNA absent from cell during cellular response to vitamin B1 starvation" EXACT [PomBase:mah] synonym: "transcripts absent from cell during cellular response to thiamine starvation" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to thiamine starvation" EXACT [PomBase:mah] is_a: FYPO:0001244 ! decreased RNA level during cellular response to thiamine starvation is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: midori creation_date: 2014-08-06T15:51:15Z [Term] id: FYPO:0003645 name: obsolete normal protein serine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "normal peptidyl-serine phosphorylation during vegetative growth" EXACT [GO:0018105] synonym: "normal protein serine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_obsolete: true replaced_by: FYPO:0000776 created_by: midori creation_date: 2014-08-06T15:54:02Z [Term] id: FYPO:0003646 name: resistance to pyrithiamine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of pyrithiamine than normal." [PomBase:mah] synonym: "resistance to pyrithiamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to pyrithiamine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to pyrithiamine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-08-06T15:56:28Z [Term] id: FYPO:0003647 name: decreased sorbose import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sorbose into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased sorbose import across plasma membrane" EXACT [GO:1903258] synonym: "decreased sorbose import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased sorbose import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sorbose import into cell" EXACT [PomBase:al] synonym: "decreased sorbose uptake" EXACT [PomBase:mah] synonym: "reduced sorbose import" EXACT [PomBase:mah] is_a: FYPO:0005973 ! abnormal transport during vegetative growth created_by: midori creation_date: 2014-08-06T16:07:43Z [Term] id: FYPO:0003648 name: abolished cell population growth on xanthine nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing xanthine as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with xanthine as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on xanthine nitrogen source" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth on xanthine nitrogen source" EXACT [PomBase:mah] synonym: "abolished xanthine utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "cell population growth on xanthine nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2014-08-06T16:10:31Z [Term] id: FYPO:0003649 name: abolished cell population growth on hypoxanthine nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing hypoxanthine as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with hypoxanthine as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on hypoxanthine nitrogen source" BROAD [PomBase:mah] synonym: "abolished hypoxanthine utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on hypoxanthine nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on hypoxanthine nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2014-08-06T16:11:05Z [Term] id: FYPO:0003650 name: decreased protein level during cellular response to glucose starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to glucose starvation is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased protein accumulation during cellular response to glucose starvation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to glucose depletion" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to glucose deprivation" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to glucose limitation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to glucose starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to glucose starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during glucose starvation" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-08-06T16:13:02Z [Term] id: FYPO:0003651 name: decreased protein level during cellular response to nitrosative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to nitrosative stress is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to nitrosative stress" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to nitrosative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to nitrosative stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to nitrosative stress" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-08-06T16:15:31Z [Term] id: FYPO:0003652 name: abnormal transcription initiation from RNA polymerase III promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription initiation from an RNA polymerase III promoter is abnormal." [GO:0006384, PomBase:mah] synonym: "abnormal transcription initiation from RNA polymerase III promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal transcription initiation from RNA polymerase III promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2014-08-06T16:28:13Z [Term] id: FYPO:0003653 name: normal transcription elongation from RNA polymerase III promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription elongation from an RNA polymerase III promoter occurs to a normal (i.e. indistinguishable from wild type) extent." [GO:0006385, PomBase:mah] synonym: "normal transcription elongation from RNA polymerase III promoter during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2014-08-06T16:29:47Z [Term] id: FYPO:0003654 name: abolished cysteine synthase activity def: "A molecular function phenotype in which cysteine synthase activity is absent." [PomBase:mah] synonym: "cysteine synthase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002754 ! abnormal cysteine synthase activity created_by: midori creation_date: 2014-08-06T16:33:28Z [Term] id: FYPO:0003655 name: abolished tRNA splicing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the splicing tRNA substrates does not occur." [GO:0006388, PomBase:mah] synonym: "abolished tRNA splicing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA splicing during vegetative growth" EXACT [PomBase:mah] synonym: "abolished tRNA splicing, via endonucleolytic cleavage and ligation" EXACT [GO:0006388] synonym: "tRNA splicing abolished" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2014-08-12T11:08:53Z [Term] id: FYPO:0003656 name: sensitive to vanadate alt_id: FYPO:0000718 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to vanadate ions (VO4(3-)). Cells stop growing (and may die) at a concentration of vanadate ions that allows wild type cells to grow." [PomBase:mah] comment: Vanadate is usually used in the form of trisodium vanadate (also known as sodium orthovanadate). synonym: "hypersensitive to trisodium vanadate" NARROW [PomBase:mah] synonym: "hypersensitive to vanadate" EXACT [PomBase:mah] synonym: "sensitive to sodium orthovanadate" NARROW [CHEBI:35607, PomBase:al] synonym: "sensitive to trisodium vanadate" NARROW [PomBase:mah] synonym: "sensitive to trisodium vanadate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to trisodium vanadate during vegetative growth" NARROW [PomBase:mah] synonym: "sensitive to vanadate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to vanadate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to vanadate ions" EXACT [PomBase:mah] synonym: "sensitive to vanadate(3-)" EXACT [CHEBI:46442] synonym: "sensitive to vanadium oxoanion" BROAD [CHEBI:30528] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-12T11:15:42Z [Term] id: FYPO:0003657 name: protein mislocalized to endoplasmic reticulum during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the endoplasmic reticulum is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the ER in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to endoplasmic reticulum during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalised to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to ER during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth is_a: FYPO:0006590 ! protein mislocalized to endoplasmic reticulum created_by: midori creation_date: 2014-08-12T11:45:33Z [Term] id: FYPO:0003658 name: normal protein localization to Golgi membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the membrane of any part of the Golgi apparatus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to Golgi membrane" EXACT [PomBase:mah] synonym: "normal protein localization to Golgi membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to Golgi membrane during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-08-12T11:47:44Z [Term] id: FYPO:0003659 name: abnormal mating type switching resulting in duplication or deletion in mating-type region def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which all or part of the mating-type region is duplicated or deleted upon mating type switching." [PMID:8290356, PomBase:mah] synonym: "abnormal mating type switching resulting in duplication or deletion in mating-type region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mating type switching resulting in duplication or deletion in mating-type region during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2014-08-12T11:57:50Z [Term] id: FYPO:0003660 name: decreased double-strand break repair during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased double-strand break repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2014-08-12T13:16:07Z [Term] id: FYPO:0003661 name: abnormal double-strand break repair via nonhomologous end joining def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is abnormal. NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity." [GO:0006303, PomBase:mah] synonym: "abnormal double-strand break repair via nonhomologous end joining during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal double-strand break repair via nonhomologous end joining during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal NHEJ" EXACT [GO:0006303] synonym: "abnormal nonhomologous end joining" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2014-08-12T13:17:31Z [Term] id: FYPO:0003662 name: increased error-free double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via an error-free mechanism, such as homologous recombination or break-induced replication, is increased." [PMID:10373582, PomBase:mah] comment: In wild-type fission yeast, double-strand breaks are usually repaired by error-prone non-homologous end joining. synonym: "increased error-free double-strand break repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased error-free double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2014-08-12T13:25:53Z [Term] id: FYPO:0003663 name: abnormal RNA pyrophosphohydrolase activity def: "A molecular function phenotype in which the observed rate of RNA pyrophosphohydrolase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-12T13:31:50Z [Term] id: FYPO:0003664 name: abolished mRNA 5'-diphosphatase activity def: "A molecular function phenotype in which mRNA 5'-diphosphatase activity is absent." [PomBase:vw] synonym: "abolished RNA pyrophosphohydrolase activity" RELATED [PomBase:vw] synonym: "RNA pyrophosphohydrolase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003663 ! abnormal RNA pyrophosphohydrolase activity created_by: midori creation_date: 2014-08-12T13:31:55Z [Term] id: FYPO:0003665 name: normal RNA pyrophosphohydrolase activity def: "A molecular function phenotype in which the observed rate of RNA pyrophosphohydrolase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-08-12T13:34:40Z [Term] id: FYPO:0003666 name: abnormal crossover junction endodeoxyribonuclease activity def: "A molecular function phenotype in which the observed rate of crossover junction endodeoxyribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-12T13:35:20Z [Term] id: FYPO:0003667 name: abolished crossover junction endodeoxyribonuclease activity def: "A molecular function phenotype in which crossover junction endodeoxyribonuclease activity is absent." [PomBase:mah] synonym: "crossover junction endodeoxyribonuclease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003666 ! abnormal crossover junction endodeoxyribonuclease activity created_by: midori creation_date: 2014-08-12T13:35:24Z [Term] id: FYPO:0003668 name: resistance to caffeine during cellular response to hydroxyurea def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caffeine than normal during a cellular response to hydroxyurea." [PomBase:mah] synonym: "resistance to caffeine during cellular response to HU" EXACT [PomBase:mah] synonym: "resistance to caffeine during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to caffeine during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to caffeine during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000073 ! resistance to caffeine created_by: midori creation_date: 2014-08-12T13:38:44Z [Term] id: FYPO:0003669 name: exon skipping def: "A cellular process phenotype in which RNA splicing does not take place at a set of splice sites that are normally used, such that an exon is omitted from the mature RNA." [PMID:17130122, PomBase:mah] synonym: "increased exon skipping" EXACT [PomBase:mah] is_a: FYPO:0003467 ! altered splice site specificity created_by: midori creation_date: 2014-08-12T13:47:58Z [Term] id: FYPO:0003670 name: sensitive to mycophenolic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mycophenolic acid. Cells stop growing (and may die) at a concentration of mycophenolic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mycophenolic acid" EXACT [PomBase:mah] synonym: "sensitive to MPA" EXACT [PMID:17130122] synonym: "sensitive to mycophenolic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to mycophenolic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-12T13:48:57Z [Term] id: FYPO:0003671 name: abnormal ATP binding def: "A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds ATP differently from wild type, or that a mutation in one gene affects ATP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-08-12T14:04:37Z [Term] id: FYPO:0003672 name: abolished ATP binding def: "A molecular function phenotype in which ATP binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with ATP that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "ATP binding abolished" EXACT [PomBase:mah] is_a: FYPO:0003671 ! abnormal ATP binding created_by: midori creation_date: 2014-08-12T14:04:46Z [Term] id: FYPO:0003673 name: normal ATP binding def: "A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-08-12T14:05:58Z [Term] id: FYPO:0003674 name: abolished ATPase activity def: "A molecular function phenotype in which ATPase activity is absent." [PomBase:mah] synonym: "ATPase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001167 ! abnormal ATPase activity created_by: midori creation_date: 2014-08-12T14:07:00Z [Term] id: FYPO:0003675 name: increased mature 5.8SL rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the large form of 5.8S rRNA measured in a cell is higher than normal." [PMID:8887563, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased 5.8SL rRNA level" BROAD [PomBase:mah] synonym: "increased mature 5.8S (L) rRNA level" EXACT [PMID:8887563] synonym: "increased mature 5.8SL rRNA accumulation" RELATED [PomBase:mah] synonym: "increased mature 5.8SL rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature 5.8SL rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature 5.8SL rRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0005996 ! altered rRNA or precursor level is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2014-08-12T14:13:07Z [Term] id: FYPO:0003676 name: abnormal 5S RNA maturation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule is abnormal." [GO:0000481, PomBase:mah] synonym: "abnormal 5S RNA maturation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal 5S RNA maturation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal 5S RNA processing" EXACT [PomBase:al] synonym: "abnormal maturation of 5S rRNA" EXACT [GO:0000481] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2014-08-12T14:30:13Z [Term] id: FYPO:0003677 name: branched, curved, elongated, multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell forms one or more branches near a septum, is elongated, has more than one septum, and is curved along the long axis." [PomBase:mah] synonym: "branched, curved, elongated, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, curved, elongated, multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched, curved, long, multiseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000134 ! branched, elongated, multiseptate cell is_a: FYPO:0005103 ! curved elongated vegetative cell created_by: midori creation_date: 2014-08-12T14:33:51Z [Term] id: FYPO:0003678 name: increased cellular doxorubicin level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of doxorubicin measured in a cell is higher than normal." [PomBase:mah] comment: Note that, because doxorubicin is not synthesized by fission yeast cells, the amount measured in a cell reflects uptake from the growth medium. synonym: "increased cellular doxorubicin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular doxorubicin level during vegetative growth" EXACT [PomBase:mah] synonym: "increased doxorubicin accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-08-12T14:48:51Z [Term] id: FYPO:0003679 name: sensitive to epirubicin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to epirubicin. Cells stop growing (and may die) at a concentration of epirubicin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to epirubicin" EXACT [PomBase:mah] synonym: "sensitive to 4'-epidoxorubicin" EXACT [CHEBI:47898] synonym: "sensitive to epirubicin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to epirubicin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-12T14:50:22Z [Term] id: FYPO:0003680 name: normal growth on epirubicin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing epirubicin." [PomBase:mah] synonym: "normal cell population growth in presence of epirubicin" EXACT [PomBase:mah] synonym: "normal cell population growth on 4'-epidoxorubicin" EXACT [CHEBI:47898, PomBase:mah] synonym: "normal cell population growth on epirubicin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to epirubicin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on epirubicin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-12T14:52:07Z [Term] id: FYPO:0003681 name: decreased protein level at centromere outer repeat heterochromatin def: "A cell phenotype in which the amount of a protein found associated with chromatin at the centromere outer repeat heterochromatin is lower than normal when the cell is in the vegetative growth phase of the life cycle." [PMID:20018856, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level at centromere otr" EXACT [PomBase:mah] synonym: "decreased protein level at centromere outer repeat chromatin" EXACT [PomBase:mah] synonym: "decreased protein level at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "decreased protein level at pericentric region" RELATED [PomBase:mah] synonym: "decreased protein level at pericentromeric region" RELATED [PomBase:mah] synonym: "reduced protein level at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-08-12T16:51:31Z [Term] id: FYPO:0003682 name: inviable after spore germination, without cell division, elongated multinucleate aseptate cell def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, is elongated, does not contain a septum, and contains more than one nucleus." [PomBase:mah] synonym: "inviable after spore germination, multinucleate aseptate elongated cell" EXACT [PomBase:mah] synonym: "inviable after spore germination, undivided elongated multinucleate aseptate cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, elongated multinucleate aseptate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, elongated multinucleate aseptate cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, elongated multinucleate aseptate cell" EXACT [PomBase:mah] is_a: FYPO:0002024 ! inviable elongated multinucleate aseptate vegetative cell is_a: FYPO:0002912 ! inviable after spore germination, without cell division, elongated multinucleate cell created_by: midori creation_date: 2014-08-18T10:58:13Z [Term] id: FYPO:0003683 name: abnormal spliceosomal complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of spliceosomal complex assembly is abnormal." [PomBase:mah] synonym: "abnormal spliceosomal complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spliceosomal complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spliceosome assembly" BROAD [GO:0000245] is_a: FYPO:0003628 ! abnormal ribonucleoprotein complex assembly created_by: midori creation_date: 2014-08-18T11:02:56Z [Term] id: FYPO:0003684 name: altered level of macromolecular complex during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of any macromolecular complex present in a cell differs from wild type." [PomBase:mah] synonym: "abnormal level of macromolecular complex during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of macromolecular complex during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0007316 ! altered level of macromolecular complex created_by: midori creation_date: 2014-08-18T11:16:42Z [Term] id: FYPO:0003685 name: decreased U2/U5/U6 snRNP complex level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer U2/U5/U6 snRNP complexes than normal." [PomBase:mah] synonym: "decreased level of U2/U5/U6 snRNP complexes" RELATED [PomBase:al] synonym: "decreased U2-type post-mRNA release spliceosomal complex level" EXACT [GO:0071008, PomBase:mah] synonym: "decreased U2/U5/U6 snRNP complex level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased U2/U5/U6 snRNP complex level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced U2/U5/U6 snRNP complex level" EXACT [PomBase:mah] synonym: "U2/U5/U6 snRNP complex present at decreased level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2014-08-18T11:20:25Z [Term] id: FYPO:0003686 name: abnormal box C/D snoRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of a box C/D snoRNA molecule is abnormal." [GO:0034472, PomBase:mah] synonym: "abnormal box C/D snoRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal box C/D snoRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007918 ! abnormal RNA 3'-end processing created_by: midori creation_date: 2014-08-18T11:41:49Z [Term] id: FYPO:0003687 name: abnormal protein localization to nucleolus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleolus" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleolus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nucleolus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2014-08-18T11:44:50Z [Term] id: FYPO:0003688 name: abolished protein localization to nucleolus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleolus" EXACT [PomBase:mah] synonym: "abolished protein localization in nucleolus" EXACT [GO:1902570] synonym: "abolished protein localization to nucleolus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleolus during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleolus abolished" EXACT [PomBase:mah] is_a: FYPO:0003687 ! abnormal protein localization to nucleolus created_by: midori creation_date: 2014-08-18T11:46:45Z [Term] id: FYPO:0003689 name: abolished protein localization to nucleolus, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleolus, with protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization in nucleolus, with protein mislocalized to cytoplasm" EXACT [GO:1902570] synonym: "abolished protein localization to nucleolus, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleolus, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleolus abolished, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0003688 ! abolished protein localization to nucleolus relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2014-08-18T11:46:48Z [Term] id: FYPO:0003690 name: abolished cell population growth on glycerol/ethanol carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing glycerol and ethanol as the carbon sources." [PomBase:mah] comment: Use this term for a population of cells that does not grow with glycerol and ethanol as the carbon sources, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on glycerol/ethanol carbon source" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth on glycerol/ethanol carbon source" EXACT [PomBase:mah] synonym: "cell population growth on glycerol/ethanol carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0000442 ! decreased cell population growth on glycerol/ethanol carbon source is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2014-08-18T11:51:55Z [Term] id: FYPO:0003691 name: increased cellular 5-demethoxyubiquinone-10 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-demethoxyubiquinone-10 ()2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone, an intermediate in ubiquinone biosynthesis) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased 5-demethoxyubiquinone-10 accumulation" RELATED [PomBase:mah] synonym: "increased cellular 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone level" EXACT [PMID:5166547] synonym: "increased cellular 5-demethoxyubiquinone-10 level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 5-demethoxyubiquinone-10 level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular demethoxyubiquinone-10 level" BROAD [PMID:18808426] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-08-18T11:55:27Z [Term] id: FYPO:0003692 name: increased protein phosphorylation during cellular response to oxidative stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to oxidative stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during oxidative stress response" EXACT [PomBase:vw] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-08-18T12:10:32Z [Term] id: FYPO:0003693 name: sulfide absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (S2-, also called acid labile sulfide) measured in a cell is too low to detect." [PomBase:mah] synonym: "sulfide absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sulfide absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "sulfide ions absent from cell" EXACT [PomBase:mah] synonym: "sulphide absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0001412 ! decreased cellular sulfide level created_by: midori creation_date: 2014-08-18T12:11:58Z [Term] id: FYPO:0003694 name: decreased mature 18S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 18S ribosomal RNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 18S rRNA level" BROAD [PomBase:mah] synonym: "decreased mature 18S rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature 18S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature 18S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature 18S rRNA transcript level" EXACT [PomBase:vw] synonym: "reduced mature 18S rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005996 ! altered rRNA or precursor level created_by: midori creation_date: 2014-08-18T12:19:48Z [Term] id: FYPO:0003695 name: decreased cytosolic small ribosomal subunit level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer free small ribosomal subunits in the cytosol than normal." [PomBase:mah] synonym: "cytosolic small ribosomal subunit present at decreased level" EXACT [PomBase:mah] synonym: "decreased 40S ribosomal subunit level" EXACT [PomBase:mah] synonym: "decreased cytosolic small ribosomal subunit level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytosolic small ribosomal subunit level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of cytosolic small ribosomal subunits" RELATED [PomBase:al] synonym: "decreased small ribosomal subunit level" BROAD [PomBase:mah] synonym: "reduced cytosolic small ribosomal subunit level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2014-08-18T12:24:03Z [Term] id: FYPO:0003696 name: increased cytosolic large ribosomal subunit level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more free large ribosomal subunits in the cytosol than normal." [PomBase:mah] synonym: "cytosolic large ribosomal subunit present at increased level" EXACT [PomBase:mah] synonym: "increased 60S ribosomal subunit level" EXACT [PomBase:mah] synonym: "increased cytosolic large ribosomal subunit level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cytosolic large ribosomal subunit level during vegetative growth" EXACT [PomBase:mah] synonym: "increased large ribosomal subunit level" BROAD [PomBase:mah] synonym: "increased level of cytosolic large ribosomal subunits" RELATED [PomBase:al] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2014-08-18T12:26:02Z [Term] id: FYPO:0003697 name: cell wall invagination into cytoplasm def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or more extensions of the cell wall protrude into the cytoplasm. The cell wall extensions do not form a normal septum." [PMID:9211982, PomBase:mah] synonym: "cell wall invagination into cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell wall invagination into cytoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000351 ! abnormal cell wall morphology during vegetative growth created_by: midori creation_date: 2014-08-18T13:12:11Z [Term] id: FYPO:0003698 name: abnormal dense body present in nucleolus def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleolus contains one or more spherical structures of great electron density that are not found in wild type cells." [PMID:9211982, PomBase:mah] synonym: "abnormal dense body present in nucleolus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal dense body present in nucleolus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000361 ! abnormal nucleolar morphology created_by: midori creation_date: 2014-08-18T13:14:45Z [Term] id: FYPO:0003699 name: snoRNA guided rRNA pseudouridine synthesis abolished at specific site def: "A cellular process phenotype in which the intramolecular conversion of uridine to pseudouridine does not occur at a specific site in an rRNA molecule that is normally modified." [GO:0000454, PMID:15716270, PomBase:mah] is_a: FYPO:0008111 ! abnormal snRNA modification created_by: midori creation_date: 2014-08-18T13:16:39Z [Term] id: FYPO:0003700 name: increased snoRNA primary transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of snoRNA primary transcripts measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased small nucleolar RNA primary transcript level" EXACT [PomBase:mah] synonym: "increased snoRNA primary transcript accumulation" RELATED [PomBase:mah] synonym: "increased snoRNA primary transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased snoRNA primary transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "increased snoRNA transcript level" BROAD [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0005998 ! altered snoRNA or precursor level created_by: midori creation_date: 2014-08-18T13:33:23Z [Term] id: FYPO:0003701 name: poly(A)+ RNA-containing focus present in nucleus def: "A physical cellular phenotype in which the nucleus contains one or more foci that are enriched in polyadenylated RNA and are not found in wild-type cells." [PMID:20129053, PomBase:mah] synonym: "poly(A)+ RNA-containing foci present in nucleus" EXACT [PomBase:mah] is_a: FYPO:0002403 ! abnormal nucleus created_by: midori creation_date: 2014-08-18T13:36:39Z [Term] id: FYPO:0003702 name: normal microtubule cytoskeleton morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the microtubule cytoskeleton is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal microtubule cytoskeleton morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-08-18T14:06:19Z [Term] id: FYPO:0003703 name: abnormal histone deacetylase activity def: "A molecular function phenotype in which the observed rate of histone deacetylase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-18T14:08:46Z [Term] id: FYPO:0003704 name: decreased histone deacetylase activity def: "A molecular function phenotype in which the observed rate of histone deacetylase activity is decreased." [PomBase:mah] synonym: "reduced histone deacetylase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003703 ! abnormal histone deacetylase activity created_by: midori creation_date: 2014-08-18T14:08:54Z [Term] id: FYPO:0003705 name: sensitive to trapoxin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trapoxin A. Cells stop growing (and may die) at a concentration of trapoxin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to trapoxin A" EXACT [PomBase:mah] synonym: "sensitive to trapoxin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to trapoxin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-18T14:12:35Z [Term] id: FYPO:0003706 name: normal growth on K-252a def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing K-252a." [PomBase:mah] synonym: "normal cell population growth in presence of K-252a" EXACT [PomBase:mah] synonym: "normal cell population growth on K-252a" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to K-252a" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on K-252a" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-18T14:14:24Z [Term] id: FYPO:0003707 name: normal growth on valinomycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing valinomycin." [PomBase:mah] synonym: "normal cell population growth in presence of valinomycin" EXACT [PomBase:mah] synonym: "normal cell population growth on valinomycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to valinomycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on valinomycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-18T14:15:15Z [Term] id: FYPO:0003708 name: normal frequency of conjugation with h+ cells def: "A conjugation phenotype in which a normal proportion of cells in the population undergoes conjugation with wild type h+ cells." [PomBase:mah] synonym: "normal conjugation with WT h+ cells" EXACT [PomBase:mah] synonym: "normal frequency of conjugation with h plus cells" EXACT [PomBase:mah] synonym: "normal frequency of mating with h+ cells" EXACT [PomBase:mah] is_a: FYPO:0003797 ! normal conjugation frequency created_by: midori creation_date: 2014-08-18T14:24:51Z [Term] id: FYPO:0003709 name: decreased agglutination def: "A cell adhesion phenotype in which cells adhere to other cells of compatible mating type less strongly or to a lower extent than normal." [PomBase:mah] synonym: "decreased agglutination involved in conjugation with cellular fusion" EXACT [GO:0000752] synonym: "reduced agglutination" EXACT [PomBase:mah] is_a: FYPO:0001872 ! abnormal cell adhesion created_by: midori creation_date: 2014-08-18T14:40:32Z [Term] id: FYPO:0003710 name: swollen pear-shaped vegetative cell def: "A cell morphology phenotype in which a cell is shaped in the form of a pear, and has a larger volume than normal, in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PomBase:mah] synonym: "swollen ice cream cone-shaped cell during vegetative growth" EXACT [PMID:2236039, PomBase:vw] synonym: "swollen pear-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "swollen pear-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001120 ! pear-shaped vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2014-08-18T16:10:38Z [Term] id: FYPO:0003711 name: lateral cortical nodes absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain any detectable Skb1-containing lateral cortical nodes." [PMID:25009287, PomBase:mah] synonym: "absent lateral cortical nodes" EXACT [PomBase:mah] synonym: "lateral cortical nodes absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lateral cortical nodes absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "Skb1-containing cortical nodes absent from cell" EXACT [PMID:25009287] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2014-08-20T11:16:31Z [Term] id: FYPO:0003712 name: lateral cortical nodes present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more Skb1-containing lateral cortical nodes than normal." [PomBase:mah] synonym: "additional lateral cortical nodes present during vegetative growth" EXACT [PomBase:mah] synonym: "extra lateral cortical nodes during vegetative growth" EXACT [PomBase:mah] synonym: "lateral cortical nodes present in greater numbers" EXACT [PomBase:mah] synonym: "lateral cortical nodes present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lateral cortical nodes present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "Skb1-containing cortical nodes present in increased numbers" EXACT [PMID:25009287] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2014-08-20T11:20:38Z [Term] id: FYPO:0003713 name: abolished protein localization to lateral cortical node def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to lateral cortical node" EXACT [PomBase:mah] synonym: "abolished protein localisation to Skb1-containing cortical node" EXACT [GO:1990463, PomBase:mah] synonym: "abolished protein localization to lateral cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to lateral cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "protein absent from lateral cortical node" RELATED [PomBase:mah] synonym: "protein localization to lateral cortical node abolished" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2014-08-20T11:30:44Z [Term] id: FYPO:0003714 name: abolished protein localization to lateral cortical node, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes is abolished, and the protein is present in the cytoplasm instead." [PMID:25009287, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to lateral cortical node, with protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to lateral cortical node abolished, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0003713 ! abolished protein localization to lateral cortical node relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2014-08-20T11:30:55Z [Term] id: FYPO:0003715 name: abolished protein localization to lateral cortical node, with protein distributed in plasma membrane or cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes is abolished, and the protein is instead detected distributed throughout the plasma membrane and/or cell cortex." [PMID:25009287, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to lateral cortical node, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein distributed in cell cortex" NARROW [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein distributed in plasma membrane" NARROW [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein distributed in plasma membrane or cortex, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein distributed in plasma membrane or cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to lateral cortical node abolished, with protein distributed in plasma membrane or cortex" EXACT [PomBase:mah] is_a: FYPO:0003713 ! abolished protein localization to lateral cortical node created_by: midori creation_date: 2014-08-20T11:34:04Z [Term] id: FYPO:0003716 name: abolished protein localization to lateral cortical node, with protein mislocalized to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes is abolished, and the protein is present in the nucleus instead." [PMID:25009287, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to lateral cortical node, with protein mislocalised to nucleus" EXACT [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein mislocalized to nucleus, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to lateral cortical node, with protein mislocalized to nucleus, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to lateral cortical node abolished, with protein mislocalized to nucleus" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth is_a: FYPO:0003713 ! abolished protein localization to lateral cortical node relationship: has_part FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2014-08-20T11:37:47Z [Term] id: FYPO:0003717 name: normal actin cytoskeleton morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actin cytoskeleton is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin cytoskeleton morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004739 ! normal actin cytoskeleton during vegetative growth created_by: midori creation_date: 2014-08-20T11:55:05Z [Term] id: FYPO:0003718 name: sensitive to tributyltin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tributyltin. Cells stop growing (and may die) at a concentration of tributyltin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tributyltin" EXACT [PomBase:mah] synonym: "sensitive to tributylstannane" EXACT [CHEBI:27086, PomBase:mah] synonym: "sensitive to tributyltin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tributyltin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-08-20T12:02:11Z [Term] id: FYPO:0003719 name: normal growth on tributyltin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tributyltin." [PomBase:mah] synonym: "normal cell population growth in presence of tributyltin" EXACT [PomBase:mah] synonym: "normal cell population growth on tributylstannane" EXACT [CHEBI:27086] synonym: "normal cell population growth on tributyltin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to tributyltin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tributyltin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-20T12:03:33Z [Term] id: FYPO:0003720 name: snoRNA guided rRNA 2'-O-methylation abolished at specific site def: "A cellular process phenotype in which the 2'-O-methylation of a nucleotide residue does not occur at a specific site in an rRNA molecule that is normally modified." [GO:0000452, PMID:17222800, PomBase:mah] is_a: FYPO:0008111 ! abnormal snRNA modification created_by: midori creation_date: 2014-08-20T13:59:03Z [Term] id: FYPO:0003721 name: normal growth on G418 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing G418." [PomBase:mah] synonym: "normal cell population growth in presence of G418" EXACT [PomBase:mah] synonym: "normal cell population growth on G418" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on Geneticin" EXACT [CHEBI:42768, PomBase:mah] synonym: "normal cellular response to G418" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on G418" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-20T14:00:57Z [Term] id: FYPO:0003722 name: decreased tRNA 5'-leader removal def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the removal of leader sequences to generate the mature 5'-end of a tRNA occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased tRNA 5'-leader removal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tRNA 5'-leader removal during vegetative growth" EXACT [PomBase:mah] synonym: "reduced tRNA 5'-leader removal" RELATED [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2014-08-20T14:06:00Z [Term] id: FYPO:0003723 name: abnormal bis(5'-adenosyl)-hexaphosphatase activity def: "A molecular function phenotype in which the observed rate of bis(5'-adenosyl)-hexaphosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-20T15:52:14Z [Term] id: FYPO:0003724 name: decreased bis(5'-adenosyl)-hexaphosphatase activity def: "A molecular function phenotype in which the observed rate of bis(5'-adenosyl)-hexaphosphatase activity is decreased." [PomBase:mah] synonym: "reduced bis(5'-adenosyl)-hexaphosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003723 ! abnormal bis(5'-adenosyl)-hexaphosphatase activity created_by: midori creation_date: 2014-08-20T15:52:20Z [Term] id: FYPO:0003725 name: increased bis(5'-adenosyl)-hexaphosphatase activity def: "A molecular function phenotype in which the observed rate of bis(5'-adenosyl)-hexaphosphatase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003723 ! abnormal bis(5'-adenosyl)-hexaphosphatase activity created_by: midori creation_date: 2014-08-20T15:52:32Z [Term] id: FYPO:0003726 name: increased cellular inositol pentakisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any myo-inositol pentakisphosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular inositol pentakisphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular inositol pentakisphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular myo-inositol pentakisphosphate level" EXACT [CHEBI:25447, PomBase:al] synonym: "increased inositol pentakisphosphate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-08-20T15:55:52Z [Term] id: FYPO:0003727 name: galactose absent from cell wall glycoprotein glycan def: "A phenotype in which the glycan moiety of a glycoprotein in the cell wall does not contain galactose residues. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages." [PMID:11378902, PMID:9125114, PomBase:mah] comment: Note that this term is not a child of 'galactose absent from cell wall' (FYPO:0002629) because the cell wall may contain galactose residues in glycans that are not part of glycosylated proteins. synonym: "abolished galactosylation of cell surface proteins" RELATED [PomBase:vw] synonym: "alpha 1,2-linked galactose residues absent from cell wall glycoprotein" EXACT [PMID:9125114, PomBase:vw] synonym: "galactose absent from cell wall glycoprotein oligosaccharide" RELATED [PomBase:vw] synonym: "galactose absent from glycoprotein glycan in cell wall" EXACT [PomBase:mah] is_a: FYPO:0002628 ! decreased level of substance in cell wall during vegetative growth is_a: FYPO:0003291 ! galactose absent from glycoprotein glycan created_by: midori creation_date: 2014-08-27T10:38:02Z [Term] id: FYPO:0003728 name: abolished protein galactosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the galactosylation of one or more specific proteins, or of specific protein sites, does not occur. Protein galactosylation is the addition of a galactose residue to a protein amino acid." [GO:0042125, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein galactosylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein galactosylation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001910 ! abnormal protein glycosylation during vegetative growth relationship: has_output FYPO:0003291 ! galactose absent from glycoprotein glycan created_by: midori creation_date: 2014-08-27T10:46:38Z [Term] id: FYPO:0003729 name: protein mislocalized to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nuclear periphery is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nuclear periphery in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nuclear periphery" EXACT [PomBase:vw] synonym: "protein mislocalised to nuclear periphery" EXACT [PomBase:mah] synonym: "protein mislocalised to nuclear periphery during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2014-08-27T14:08:07Z [Term] id: FYPO:0003730 name: abolished cell population growth on galactose carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing galactose as the carbon source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with galactose as the carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished galactose utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished growth on galactose carbon source" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth on galactose carbon source" EXACT [PomBase:mah] synonym: "cell population growth on galactose carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0000251 ! decreased cell population growth on galactose carbon source is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2014-08-27T14:23:02Z [Term] id: FYPO:0003731 name: normal growth on galactose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing galactose as the carbon source." [PomBase:mah] synonym: "normal cell population growth on galactose carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on galactose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-08-27T14:24:18Z [Term] id: FYPO:0003732 name: mitochondrial respiratory chain complex IV absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain any detectable respiratory chain complex IV in the mitochondria." [PMID:16911509, PomBase:mah] synonym: "absent mitochondrial respiratory chain complex IV" EXACT [PomBase:mah] synonym: "mitochondrial respiratory chain complex IV absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial respiratory chain complex IV absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2014-08-27T14:27:19Z [Term] id: FYPO:0003733 name: abnormal alcohol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of alcohol dehydrogenase activity is abnormal." [PomBase:mah] synonym: "alcohol dehydrogenase (NAD) activity" EXACT [GO:0004022] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-08-27T14:45:07Z [Term] id: FYPO:0003734 name: decreased alcohol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of alcohol dehydrogenase activity is decreased." [PomBase:mah] synonym: "decreased alcohol dehydrogenase (NAD) activity" EXACT [GO:0004022] synonym: "reduced alcohol dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003733 ! abnormal alcohol dehydrogenase activity created_by: midori creation_date: 2014-08-27T14:45:18Z [Term] id: FYPO:0003735 name: altered DNA binding specificity def: "A molecular function phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:7651412, PomBase:mah] synonym: "abnormal DNA binding specificity" EXACT [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2014-08-27T15:09:29Z [Term] id: FYPO:0003736 name: normal mitotic index def: "A cell population phenotype in which the mitotic index is normal (i.e. indistinguishable from wild type). The mitotic index is the proportion of the population undergoing mitosis at any given time." [PomBase:mah, PomBase:vw] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2014-08-27T15:16:49Z [Term] id: FYPO:0003737 name: delayed onset of protein phosphorylation during mitotic G2 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during G2 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein phosphorylation during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein phosphorylation during mitotic G2-phase" EXACT [PomBase:vw] synonym: "delayed onset of protein/peptide phosphorylation during mitotic G2 phase" EXACT [PomBase:mah] synonym: "delayed protein phosphorylation during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0002830 ! delayed onset of protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-08-27T15:30:55Z [Term] id: FYPO:0003738 name: abnormal mitotic cell cycle arrest with condensed chromosomes def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have condensed chromosomes, but show no other signs of having entered mitosis or M phase, under conditions where arrest does not normally occur." [PomBase:mah] comment: Note that in wild-type cells, chromosomes are condensed only in M phase. This term can be used for mutants in which chromosomes are condensed but other normal features of M phase cells are not observed. synonym: "abnormal cell cycle arrest with condensed chromosomes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with condensed chromosomes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression created_by: midori creation_date: 2014-08-27T15:31:53Z [Term] id: FYPO:0003739 name: decreased DNA replication origin binding def: "A molecular function phenotype in which occurrence of DNA binding at a replication origin by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased origin binding" EXACT [PomBase:mah] synonym: "reduced DNA replication origin binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2014-08-27T16:12:31Z [Term] id: FYPO:0003740 name: decreased CENP-A containing chromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) occurs to a lower extent than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions." [GO:0034080, PomBase:mah] synonym: "decreased CenH3-containing nucleosome assembly at centromere" RELATED [GO:0034080] synonym: "decreased CENP-A containing nucleosome assembly" RELATED [] synonym: "decreased CENP-A containing nucleosome assembly at centromere" EXACT [PomBase:mah] synonym: "decreased CENP-A containing nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased CENP-A containing nucleosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased CENP-A deposition" RELATED [GO:0034080] synonym: "decreased CENP-A loading" RELATED [GO:0034080] synonym: "decreased centromere-specific histone exchange" EXACT [GO:0034080] synonym: "decreased centromere-specific nucleosome assembly" EXACT [GO:0034080] synonym: "decreased centromeric DNA replication-independent nucleosome assembly" EXACT [GO:0034080] synonym: "decreased DNA replication-independent nucleosome assembly at centromere" EXACT [GO:0034080] synonym: "reduced CENP-A containing nucleosome assembly" EXACT [PomBase:mah] is_a: FYPO:0003409 ! abnormal CENP-A containing chromatin assembly is_a: FYPO:0006356 ! abnormal chromatin remodeling created_by: midori creation_date: 2014-08-27T16:19:51Z [Term] id: FYPO:0003741 name: abolished cytochrome-c oxidase activity def: "A molecular function phenotype in which cytochrome-c oxidase activity is absent." [PomBase:mah] synonym: "cytochrome-c oxidase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001937 ! abnormal cytochrome-c oxidase activity created_by: midori creation_date: 2014-09-01T13:45:17Z [Term] id: FYPO:0003742 name: inviable after spore germination, multiple cell divisions, unequal chromosome segregation def: "A phenotype in which a spore germinates to produce a cell that undergoes two or more rounds of cell division during which chromosomes segregate unequally, and then dies." [PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, unequal chromosome segregation" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, unequal chromosome segregation" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, unequal chromosome segregation" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2014-09-01T13:52:53Z [Term] id: FYPO:0003743 name: decreased cell population growth during glucose starvation def: "A cell growth phenotype in which cell population growth is decreased relative to normal under conditions of glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased cell population growth during glucose depletion" EXACT [PomBase:mah] synonym: "decreased cell population growth during glucose deprivation" EXACT [PomBase:mah] synonym: "decreased cell population growth during glucose limitation" RELATED [PomBase:mah] synonym: "decreased cell population growth in response to glucose starvation" EXACT [PomBase:mah] synonym: "hypersensitive to glucose starvation" RELATED [PomBase:mah] synonym: "reduced cell population growth during glucose starvation" RELATED [PomBase:mah] synonym: "sensitive to glucose starvation" RELATED [PomBase:vw] synonym: "slow cell population growth during glucose starvation" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2014-09-08T11:52:09Z [Term] id: FYPO:0003744 name: abolished protein localization to centromeric chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to centromeric chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to centromeric chromatin during vegetative growth abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000634 ! abolished protein localization to centromere during vegetative growth is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth is_a: FYPO:0005306 ! abnormal protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2014-09-01T14:23:24Z [Term] id: FYPO:0003745 name: increased histone H3 acetylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal in the central core of the centromeric regions." [PomBase:mah] synonym: "increased histone H3 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002363 ! increased histone H3 acetylation during vegetative growth created_by: midori creation_date: 2014-09-01T14:32:10Z [Term] id: FYPO:0003746 name: increased histone H3-K9 methylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin islands occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9me at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at heterochromatin island during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2014-09-01T14:49:33Z [Term] id: FYPO:0003747 name: normal level of DSR-containing meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during meiosis, and that contain determinant of selective removal (DSR) sequences, measured in a cell is normal (i.e. indistinguishable from wild type)." [PMID:24713849, PomBase:mah] synonym: "normal DSR-containing meiotic gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "normal level of DSR-containing meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of DSR-containing meiotic gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of DSR-containing meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of DSR-containing meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "normal level of DSR-containing meiotic nuclear division gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007281 ! normal level of meiotic gene mRNA during vegetative growth created_by: midori creation_date: 2014-09-01T14:54:07Z [Term] id: FYPO:0003748 name: abnormal protein localization to nuclear body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear bodies is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nuclear body" EXACT [PomBase:mah] synonym: "abnormal protein localization to nuclear body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to nuclear body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2014-09-01T15:15:14Z [Term] id: FYPO:0003749 name: abolished positive regulation of m7G(5')pppN diphosphatase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of m7G(5')pppN diphosphatase activity does not occur." [PMID:22323607, PomBase:mah] synonym: "abolished positive regulation of m7G(5')pppN diphosphatase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished positive regulation of m7G(5')pppN diphosphatase activity during vegetative growth" EXACT [PomBase:mah] synonym: "positive regulation of m7G(5')pppN diphosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2014-09-01T15:29:36Z [Term] id: FYPO:0003750 name: normal nuclear pore density def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a normal number of nuclear pore complexes." [PMID:9372936, PomBase:mah] synonym: "normal NPC density" EXACT [PomBase:mah] synonym: "normal nuclear pore complex density" EXACT [PomBase:mah] synonym: "normal nuclear pore density during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal nuclear pore density during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear pore complexes present in normal number" EXACT [GO:0005643] synonym: "nuclear pores present in normal number" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-09-01T16:03:26Z [Term] id: FYPO:0003751 name: normal nuclear envelope morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "normal nuclear envelope morphology during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal nuclear envelope morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear membrane morphology" NARROW [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-09-01T16:07:55Z [Term] id: FYPO:0003752 name: increased total nuclear polyadenylated mRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of polyadenylated messenger RNA (mRNA) measured in the nucleus is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of bulk nuclear polyadenylated mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of total nuclear polyadenylated mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased nuclear bulk poly(A)+ mRNA level during vegetative growth" EXACT [PomBase:vw] synonym: "increased total nuclear polyadenylated messenger RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased total nuclear polyadenylated mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased total nuclear polyadenylated mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased total nuclear polyadenylated mRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "total nuclear poly(A)+ mRNA accumulation" RELATED [PomBase:vw] synonym: "total nuclear poly-A mRNA accumulation" RELATED [PomBase:vw] is_a: FYPO:0003119 ! increased nuclear polyadenylated mRNA level during vegetative growth created_by: midori creation_date: 2014-09-01T16:26:37Z [Term] id: FYPO:0003753 name: increased specific nuclear polyadenylated mRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more specific polyadenylated messenger RNAs (mRNAs) measured in the nucleus is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased level of specific nuclear polyadenylated mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased nuclear specific poly(A)+ mRNA level during vegetative growth" EXACT [PomBase:vw] synonym: "increased specific nuclear polyadenylated messenger RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased specific nuclear polyadenylated mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased specific nuclear polyadenylated mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased specific nuclear polyadenylated mRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "specific nuclear poly(A)+ mRNA accumulation" RELATED [PomBase:vw] synonym: "specific nuclear poly-A mRNA accumulation" RELATED [PomBase:vw] is_a: FYPO:0003119 ! increased nuclear polyadenylated mRNA level during vegetative growth created_by: midori creation_date: 2014-09-01T16:28:38Z [Term] id: FYPO:0003754 name: multiple mitotic spindles def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one mitotic spindle." [PomBase:mah] synonym: "additional mitotic spindles present during vegetative growth" EXACT [PomBase:mah] synonym: "extra mitotic spindles during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of mitotic spindles" EXACT [PomBase:vw] synonym: "mitotic spindles present in greater numbers during vegetative growth" EXACT [PomBase:mah] synonym: "multiple spindles during mitosis" EXACT [PomBase:mah] synonym: "multiple spindles during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2014-09-01T16:36:05Z [Term] id: FYPO:0003755 name: abnormal vegetative cell phenotype def: "A phenotype that shows detectable differences from normal at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal cell phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vegetative cell phenotype during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal vegetative fission yeast cell phenotype" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype is_a: FYPO:0003037 ! abnormal cell phenotype relationship: inheres_in FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2014-09-01T17:20:24Z [Term] id: FYPO:0003756 name: multiple mitotic spindles with abolished sister chromatid separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has more than one mitotic spindle, and mitotic sister chromatid separation does not occur." [PMID:8978688, PomBase:mah] synonym: "multiple mitotic spindles with abolished chromosome separation" EXACT [PomBase:mah] synonym: "multiple mitotic spindles with abolished sister chromatid segregation" RELATED [PomBase:vw] synonym: "multiple mitotic spindles with abolished sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiple mitotic spindles with abolished sister chromatid separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001946 ! abolished mitotic sister chromatid separation is_a: FYPO:0003754 ! multiple mitotic spindles is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2014-09-01T17:24:07Z [Term] id: FYPO:0003757 name: incomplete mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes; some, but not all, DNA may be moved towards the ends of an elongated mitotic spindle." [PMID:8978688, PomBase:mah, PomBase:vw] synonym: "arrested mitotic sister chromatid segregation" RELATED [PATO:0000297] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2014-09-01T17:30:48Z [Term] id: FYPO:0003758 name: mitotic spindle elongation without chromosome separation def: "A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes." [PMID:8978688, PomBase:mah, PomBase:vw] comment: Note that cells with this phenotype often (but not always) proceed to a cut (FYPO:0003165) phenotype. synonym: "archery-bow phenotype" EXACT [PMID:8978688] synonym: "incomplete mitotic sister chromatid segregation, with elongated mitotic spindle and unseparated DNA" EXACT [PomBase:mah] synonym: "incomplete mitotic sister chromatid segregation, with unseparated DNA" EXACT [PomBase:mah] synonym: "incomplete mitotic sister chromatid separation, with unseparated DNA" RELATED [PomBase:mah] synonym: "spindle elongation in absence of chromosome separation" EXACT [PomBase:mah] synonym: "spindle elongation without chromosome separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle elongation without chromosome separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001946 ! abolished mitotic sister chromatid separation is_a: FYPO:0003757 ! incomplete mitotic sister chromatid segregation relationship: has_part FYPO:0001946 ! abolished mitotic sister chromatid separation relationship: output_of FYPO:0000444 ! abnormal mitotic cell cycle arrest with replicated DNA created_by: midori creation_date: 2014-09-01T17:31:22Z [Term] id: FYPO:0003759 name: inviable after spore germination, single or double cell division, arrest with single nucleus def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a single nucleus and then die." [PomBase:mah, PomBase:vw] synonym: "inviable following spore germination, single or double cell division, arrest with single nucleus" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, arrest with single nucleus" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, arrest with single nucleus" EXACT [PomBase:mah] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0001042 ! inviable after spore germination, single or double cell division is_a: FYPO:0001924 ! inviable after spore germination, without cell division, cell cycle arrest relationship: has_part FYPO:0000060 ! mononucleate vegetative cell created_by: midori creation_date: 2014-09-01T19:20:58Z [Term] id: FYPO:0003760 name: inviable after spore germination, single or double cell division, arrest with cut def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a cut phenotype, and then die." [PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, single or double cell division, arrest with septation following abnormal mitotic chromosome segregation" EXACT [PomBase:vw] synonym: "inviable following spore germination, single or double cell division, arrest with cut" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, arrest with cut" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, arrest with cut" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0003250 ! premature septum assembly is_a: FYPO:0003759 ! inviable after spore germination, single or double cell division, arrest with single nucleus is_a: FYPO:0006430 ! inviable mononucleate vegetative cell relationship: has_part FYPO:0000229 ! cut created_by: midori creation_date: 2014-09-01T19:22:23Z [Term] id: FYPO:0003761 name: obsolete inviable after spore germination, single or double cell division, arrest with anucleate cell def: "OBSOLETE. A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a septum separating a compartment with one nucleus and a second compartment with no nucleus, and then die." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it was requested in error and does not make sense. synonym: "inviable following spore germination, single or double cell division, arrest with anucleate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, arrest with anucleate cell" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2014-09-01T19:23:46Z [Term] id: FYPO:0003762 name: normal mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the mitotic cell cycle spindle assembly checkpoint is normal (i.e. indistinguishable from wild type). The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PomBase:mah] synonym: "normal mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "normal mitotic spindle assembly checkpoint activation" RELATED [PomBase:mah] synonym: "normal spindle assembly checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal spindle assembly checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001703 ! normal mitotic cell cycle checkpoint created_by: midori creation_date: 2014-09-01T19:26:20Z [Term] id: FYPO:0003763 name: inviable aseptate mononucleate vegetative cell def: "A cell phenotype in which a cell is inviable and contains one nucleus and no septum." [PomBase:mah] synonym: "inviable aseptate mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable aseptate mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "inviable unseptated mononucleate vegetative cell" EXACT [PomBase:mah] synonym: "lethal; aseptate mononucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0003785 ! aseptate mononucleate vegetative cell is_a: FYPO:0003931 ! inviable aseptate vegetative cell is_a: FYPO:0006430 ! inviable mononucleate vegetative cell created_by: midori creation_date: 2014-09-08T12:24:07Z [Term] id: FYPO:0003764 name: inviable after spore germination, single or double cell division, arrest with aseptate mononucleate cell def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with one nucleus and no septum, and then die." [PomBase:mah, PomBase:vw] synonym: "inviable following spore germination, single or double cell division, arrest with aseptate mononucleate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, arrest with aseptate mononucleate cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, arrest with aseptate mononucleate cell" EXACT [PomBase:mah] is_a: FYPO:0003759 ! inviable after spore germination, single or double cell division, arrest with single nucleus is_a: FYPO:0003763 ! inviable aseptate mononucleate vegetative cell created_by: midori creation_date: 2014-09-08T12:30:32Z [Term] id: FYPO:0003766 name: aggregated mtDNA def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial DNA molecules are interlinked by unresolved recombination junctions." [PMID:10954073, PomBase:mah] synonym: "aggregated mitochondrial chromosomes" EXACT [PomBase:mah] synonym: "aggregated mitochondrial DNA" EXACT [PomBase:mah] synonym: "aggregated mtDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "aggregated mtDNA during vegetative growth" EXACT [PomBase:mah] synonym: "fused mitochondrial chromosomes" RELATED [PomBase:mah] synonym: "fused mtDNA" RELATED [PomBase:mah] synonym: "interlinked mtDNA" EXACT [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2014-09-08T15:12:12Z [Term] id: FYPO:0003767 name: decreased crossover junction endodeoxyribonuclease activity def: "A molecular function phenotype in which the observed rate of crossover junction endodeoxyribonuclease activity is decreased." [PomBase:mah] synonym: "reduced crossover junction endodeoxyribonuclease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003666 ! abnormal crossover junction endodeoxyribonuclease activity created_by: midori creation_date: 2014-09-08T15:23:36Z [Term] id: FYPO:0003768 name: normal protein localization to mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitochondrion" EXACT [PomBase:mah] synonym: "normal protein localization to mitochondria" EXACT [PomBase:mah] synonym: "normal protein localization to mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to mitochondrion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2014-09-08T15:25:25Z [Term] id: FYPO:0003769 name: decreased cellular mtDNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial DNA present in the cell is lower than normal." [PomBase:mah] synonym: "decreased mitochondrial DNA content" EXACT [PomBase:mah] synonym: "decreased mitochondrial DNA copy number" RELATED [PMID:28334955, PomBase:vw] synonym: "decreased mitochondrial DNA level" EXACT [PomBase:mah] synonym: "decreased mitochondrial genome copy number" RELATED [PMID:28334955, PomBase:vw] synonym: "decreased mtDNA level" EXACT [PomBase:mah] synonym: "decreased mtDNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mtDNA level during vegetative growth" EXACT [PomBase:mah] synonym: "loss of mitochondrial DNA" EXACT [PomBase:vw] synonym: "reduced mitochondrial DNA content" EXACT [PomBase:mah] synonym: "reduced mtDNA level" EXACT [PomBase:mah] is_a: FYPO:0000453 ! DNA content decreased during vegetative growth created_by: midori creation_date: 2014-09-08T15:29:40Z [Term] id: FYPO:0003770 name: decreased transcriptional response to pheromone def: "A transcription regulation phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter is decreased." [GO:0007329, PomBase:mah] synonym: "decreased positive regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0007329] synonym: "reduced positive regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0007329] is_a: FYPO:0000623 ! abnormal positive regulation of transcription is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2014-09-08T15:44:26Z [Term] id: FYPO:0003771 name: decreased protein localization to plasma membrane of cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell tip is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to plasma membrane of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization in plasma membrane of cell tip during vegetative growth" EXACT [GO:1903418] synonym: "decreased protein localization to plasma membrane of cell end during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to plasma membrane of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to plasma membrane of cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008198 ! decreased protein localization to plasma membrane during vegetative growth created_by: midori creation_date: 2014-09-08T16:10:02Z [Term] id: FYPO:0003772 name: normal transposon gene mRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of messenger RNA derived from transposon-encoded genes measured in a cell is normal (i.e. indistinguishable from wild type)." [PMID:10022921, PomBase:mah] synonym: "normal level of transposon gene mRNA" EXACT [PomBase:mah] synonym: "normal transposon gene mRNA accumulation" RELATED [PomBase:mah] synonym: "normal transposon gene mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transposon gene mRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal transposon gene RNA level" EXACT [PomBase:mah] synonym: "normal transposon gene transcript level" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2014-09-08T16:39:44Z [Term] id: FYPO:0003773 name: normal level of transposon-encoded protein in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transposon-encoded proteins measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of transposon-encoded protein during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of transposon-encoded protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transposon-encoded protein accumulation" RELATED [PomBase:mah] synonym: "normal transposon-encoded protein level" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2014-09-08T16:42:46Z [Term] id: FYPO:0003774 name: normal level of transposon-derived cDNA in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cDNA derived from transposon-encoded genes measured in a cell is normal (i.e. indistinguishable from wild type)." [PMID:10022921, PomBase:mah] synonym: "normal cellular level of transposon-derived cDNA" EXACT [PomBase:mah] synonym: "normal level of transposon-derived cDNA in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of transposon-derived cDNA in cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2014-09-08T16:47:22Z [Term] id: FYPO:0003775 name: decreased transposon-derived cDNA recombination def: "A cellular process phenotype in which the occurrence of DNA recombination between cDNAs derived from transposon-encoded genes is decreased." [PMID:10022921, PomBase:mah] synonym: "decreased recombination of transposon-derived cDNAs" EXACT [PomBase:mah] synonym: "decreased transposon-derived cDNA recombination frequency" EXACT [PomBase:mah] synonym: "decreased transposon-derived cDNA recombination rate" RELATED [PomBase:mah] synonym: "reduced transposon-derived cDNA recombination" EXACT [PomBase:mah] is_a: FYPO:0002712 ! decreased DNA recombination created_by: midori creation_date: 2014-09-08T16:49:50Z [Term] id: FYPO:0003776 name: increased pseudohyphal growth def: "A cellular process phenotype in which the occurrence of pseudohyphal growth is increased." [PomBase:mah] synonym: "increased filamentous growth" BROAD [PomBase:mah] is_a: FYPO:0000550 ! abnormal pseudohyphal growth created_by: midori creation_date: 2014-09-08T16:51:59Z [Term] id: FYPO:0003777 name: abnormal protein localization to endoplasmic reticulum during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the ER and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to ER during vegetative growth" EXACT [GO:0005783, PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0006377 ! abnormal protein localization to endoplasmic reticulum created_by: midori creation_date: 2014-09-08T17:10:58Z [Term] id: FYPO:0003778 name: decreased protein localization to endoplasmic reticulum tubular network def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum tubular network is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to endoplasmic reticulum tubular network" EXACT [PomBase:mah] synonym: "decreased protein localization to endoplasmic reticulum tubular network during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to endoplasmic reticulum tubular network during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to ER tubular network" EXACT [GO:0071782, PomBase:mah] synonym: "decreased protein localization to tubular ER" EXACT [PomBase:al] synonym: "reduced protein localization to endoplasmic reticulum tubular network" EXACT [PomBase:mah] is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth created_by: midori creation_date: 2014-09-08T17:13:21Z [Term] id: FYPO:0003779 name: abnormal nuclear envelope morphology during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is abnormal during mitosis." [PomBase:mah] comment: Note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "abnormal nuclear envelope morphology during mitotic M phase" RELATED [PomBase:mah] synonym: "abnormal nuclear envelope morphology during mitotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal nuclear membrane morphology during mitosis" NARROW [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2014-09-08T17:20:22Z [Term] id: FYPO:0003780 name: normal nuclear envelope morphology during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] synonym: "normal nuclear envelope morphology during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear envelope morphology during mitotic M phase" RELATED [PomBase:mah] synonym: "normal nuclear envelope morphology during mitotic nuclear division" EXACT [PomBase:mah] synonym: "normal nuclear membrane morphology during mitosis" NARROW [PomBase:mah] is_a: FYPO:0003751 ! normal nuclear envelope morphology created_by: midori creation_date: 2014-09-08T17:21:52Z [Term] id: FYPO:0003781 name: normal nuclear envelope morphology during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal nuclear envelope morphology during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear envelope morphology during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal nuclear membrane morphology during mitotic interphase" NARROW [PomBase:mah] is_a: FYPO:0003751 ! normal nuclear envelope morphology created_by: midori creation_date: 2014-09-08T17:23:16Z [Term] id: FYPO:0003782 name: normal nuclear pore localization during mitotic interphase def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is normal (i.e. indistinguishable from wild type), resulting in a normal spatial arrangement of nuclear pores within the nuclear envelope, during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal NPC localization during mitotic interphase" EXACT [PomBase:mah] synonym: "normal nuclear pore complex localization during mitotic interphase" EXACT [PomBase:mah] synonym: "normal nuclear pore distribution during mitotic interphase" EXACT [GO:0051664] synonym: "normal nuclear pore localisation during mitotic interphase" EXACT [PomBase:mah] synonym: "normal nuclear pore localization during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear pore localization during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear pore localization during interphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000771 ! normal nuclear pore localization created_by: midori creation_date: 2014-09-08T17:24:43Z [Term] id: FYPO:0003783 name: abnormal nuclear pore localization during mitosis def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is abnormal, resulting in an abnormal spatial arrangement of nuclear pores within the nuclear envelope, during mitosis." [PomBase:mah] synonym: "abnormal NPC localization during mitosis" EXACT [PomBase:mah] synonym: "abnormal nuclear pore complex localization during mitosis" EXACT [PomBase:mah] synonym: "abnormal nuclear pore distribution during mitosis" EXACT [PomBase:mah] synonym: "abnormal nuclear pore localisation during mitosis" EXACT [GO:0051664] synonym: "abnormal nuclear pore localization during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nuclear pore localization during mitotic M phase" RELATED [PomBase:mah] synonym: "abnormal nuclear pore localization during mitotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0003973 ! abnormal nuclear pore localization created_by: midori creation_date: 2014-09-08T17:25:07Z [Term] id: FYPO:0003784 name: inviable after spore germination, single or double cell division, arrest with septated mononucleate cell def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a septum and a nucleus in one compartment, and then die." [PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, single or double cell division, arrest with septated cell and single nucleus" EXACT [PomBase:vw] synonym: "inviable following spore germination, single or double cell division, arrest with septated mononucleate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, arrest with septated mononucleate cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, arrest with septated mononucleate cell" EXACT [PomBase:mah] is_a: FYPO:0002000 ! inviable septated mononucleate vegetative cell is_a: FYPO:0003759 ! inviable after spore germination, single or double cell division, arrest with single nucleus created_by: midori creation_date: 2014-09-09T11:07:33Z [Term] id: FYPO:0003785 name: aseptate mononucleate vegetative cell def: "A cell phenotype in which a cell contains one nucleus and no septum." [PomBase:mah] synonym: "aseptate mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "aseptate mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mononucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "unseptated mononucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0000949 ! aseptate relationship: has_part FYPO:0000060 ! mononucleate vegetative cell relationship: has_part FYPO:0000949 ! aseptate created_by: midori creation_date: 2014-09-09T11:19:49Z [Term] id: FYPO:0003786 name: abolished protein localization to centromere central core during vegetative growth alt_id: FYPO:0003765 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to centromere central core abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to chromatin at centromere central core abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003744 ! abolished protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2014-09-09T13:24:06Z [Term] id: FYPO:0003787 name: long mitotic spindle microtubules protruding beyond spindle pole body def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form mitotic spindle microtubules that are longer than normal, and extend beyond the spindle pole body. The protruding spindle microtubules are surrounded by an extension of the nuclear envelope." [PMID:17486116, PomBase:mah] synonym: "elongated mitotic spindle microtubules protruding from spindle pole body" EXACT [PomBase:mah] synonym: "elongated mitotic spindle microtubules protruding from spindle pole body during M-phase" EXACT [PomBase:vw] synonym: "long mitotic spindle microtubules protruding beyond spindle pole body, with nuclear envelope deformation" RELATED [PomBase:vw] synonym: "long mitotic spindle microtubules protruding beyond spindle pole body, with nuclear envelope protrusion" EXACT [PomBase:vw] synonym: "long mitotic spindle microtubules protruding from SPB" EXACT [PomBase:mah] synonym: "long mitotic spindle microtubules protruding from spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long mitotic spindle microtubules protruding from spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "long nuclear microtubules protruding through nuclear envelope" RELATED [] synonym: "mitotic spindle microtubules protruding beyond spindle pole body" BROAD [PomBase:mlr] synonym: "nuclear envelope protrusion with long mitotic spindle microtubules protruding beyond spindle pole body" EXACT [PomBase:vw] is_a: FYPO:0000055 ! long microtubules is_a: FYPO:0000733 ! long mitotic spindle is_a: FYPO:0003788 ! nuclear envelope protrusion present during mitosis relationship: has_part FYPO:0003788 ! nuclear envelope protrusion present during mitosis created_by: midori creation_date: 2014-09-09T13:26:10Z [Term] id: FYPO:0003788 name: nuclear envelope protrusion present during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has one or more extensions that protrude into the cytoplasm during mitosis." [PMID:17486116, PMID:25103238, PomBase:mah] comment: This term differs from 'lobate nuclear envelope' (FYPO:0002005) in that a lobate envelope has a few deep fissures extending inward from the cytoplasm that appear to partially divide the nucleus into portions, whereas protrusions are smaller and extend outward from the bulk of the nucleus. synonym: "nuclear envelope deformation during mitosis" RELATED [PomBase:vw] synonym: "nuclear envelope protrusion present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear envelope protrusion present during mitotic M phase" RELATED [PomBase:mah] synonym: "nuclear envelope protrusion present during mitotic nuclear division" EXACT [GO:0140014] synonym: "nuclear envelope protrusion present during vegetative growth" EXACT [PomBase:mah] synonym: "protruding nuclear envelope during mitosis" EXACT [PomBase:mah] is_a: FYPO:0003779 ! abnormal nuclear envelope morphology during mitosis created_by: midori creation_date: 2014-09-09T13:34:47Z [Term] id: FYPO:0003789 name: decreased frequency of meiosis II def: "A cell population phenotype in which the frequency of occurrence of the second meiotic nuclear division, in which two chromatids in each chromosome are normally separated, is decreased." [PomBase:mah] synonym: "decreased frequency of second meiotic nuclear division" EXACT [PomBase:al] synonym: "decreased meiosis II" EXACT [PomBase:mah] synonym: "meiosis II: decreased frequency" EXACT [PomBase:mah] synonym: "reduced frequency of meiosis II" EXACT [PomBase:mah] is_a: FYPO:0000476 ! decreased frequency of meiosis created_by: midori creation_date: 2014-09-09T14:01:31Z [Term] id: FYPO:0003790 name: normal protein localization during meiosis def: "A cell phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type) during the first or second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation during meiosis" EXACT [PomBase:mah] synonym: "normal protein localization during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004095 ! normal protein localization during meiotic cell cycle created_by: midori creation_date: 2014-09-09T14:03:28Z [Term] id: FYPO:0003791 name: increased meiotic recombination at silent mating-type cassette def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is increased at the silent mating-type cassettes." [PomBase:mah] synonym: "increased meiotic recombination at mating-type region heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0000487 ! increased meiotic recombination is_a: FYPO:0003346 ! abnormal meiotic recombination at silent mating-type cassette created_by: midori creation_date: 2014-09-09T14:37:37Z [Term] id: FYPO:0003792 name: increased meiotic DNA double-strand break formation at silent mating-type cassette def: "A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is increased at the silent mating-type cassettes." [PomBase:mah] synonym: "increased meiotic DNA double-strand break formation at mating-type region heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0003346 ! abnormal meiotic recombination at silent mating-type cassette created_by: midori creation_date: 2014-09-09T14:41:21Z [Term] id: FYPO:0003793 name: normal RNA level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to osmotic stress is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to osmotic stress" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2014-09-09T14:57:46Z [Term] id: FYPO:0003794 name: normal cellular glycerol level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell is normal (i.e. indistinguishable from wild type) during a cellular response to osmotic stress." [PomBase:mah] synonym: "normal cellular glycerol accumulation during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "normal cellular glycerol level during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular glycerol level during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2014-09-09T15:00:03Z [Term] id: FYPO:0003795 name: normal cell wall alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell wall alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "normal cell wall alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "normal cell wall alpha-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell wall alpha-glucan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001196 ! normal alpha-glucan level created_by: midori creation_date: 2014-09-09T15:07:56Z [Term] id: FYPO:0003796 name: abolished transcription from RNA polymerase II promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from an RNA polymerase II promoter does not occur. All genes, or a specific subset of genes, may be affected." [PMID:16874521, PomBase:mah] synonym: "abolished transcription from RNA polymerase II promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished transcription from RNA polymerase II promoter during vegetative growth" EXACT [PomBase:mah] synonym: "transcription from RNA polymerase II promoter abolished" EXACT [PomBase:mah] is_a: FYPO:0001443 ! abolished transcription during vegetative growth is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2014-09-09T15:27:35Z [Term] id: FYPO:0003797 name: normal conjugation frequency def: "A cell population phenotype in which a normal (i.e. indistinguishable from wild type) proportion of cells in the population undergoes conjugation." [PomBase:mah] comment: Note that this term refers specifically to conjugation, whereas experiments that measure mating efficiency often do so by counting zygotes plus asci, sometimes also including spores. For such experiments, we recommend using 'normal mating efficiency' (FYPO:0001147). synonym: "normal conjugation efficiency" RELATED [PomBase:mah] synonym: "normal mating frequency" EXACT [PomBase:mah] synonym: "normal occurrence of conjugation" EXACT [PomBase:mah] synonym: "normal zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype relationship: part_of FYPO:0000760 ! normal mating created_by: midori creation_date: 2014-09-09T15:33:50Z [Term] id: FYPO:0003798 name: normal meiosis II def: "A cellular process phenotype in which the second meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-09-09T15:36:52Z [Term] id: FYPO:0003799 name: normal chromatin binding during recovery from nitrogen starvation def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) in cells that are returned to nitrogen-rich medium following nitrogen starvation." [PomBase:mah] synonym: "normal chromatin binding during recovery from nitrogen depletion" EXACT [PomBase:mah] synonym: "normal chromatin binding during recovery from nitrogen deprivation" RELATED [PomBase:mah] is_a: FYPO:0003086 ! normal chromatin binding created_by: midori creation_date: 2014-09-12T13:19:06Z [Term] id: FYPO:0003800 name: normal chromatin binding at replication origin def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at an origin of replication." [PomBase:mah] synonym: "normal chromatin binding at origin of replication" EXACT [PomBase:mah] is_a: FYPO:0003086 ! normal chromatin binding created_by: midori creation_date: 2014-09-12T13:30:03Z [Term] id: FYPO:0003801 name: decreased chromatin binding at replication origin def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at an origin of replication is decreased." [PomBase:mah] synonym: "decreased chromatin binding at origin of replication" EXACT [PomBase:mah] synonym: "reduced chromatin binding at replication origin" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2014-09-12T13:32:07Z [Term] id: FYPO:0003802 name: increased histone H3-K14 acetylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in telomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2014-09-12T13:39:30Z [Term] id: FYPO:0003803 name: decreased protein localization to telomere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to telomere" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome, telomeric region" EXACT [GO:0070198, PomBase:mah] synonym: "decreased protein localization to telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to telomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to telomeric region" EXACT [PomBase:vw] synonym: "reduced protein localization to telomere" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2014-09-12T13:45:25Z [Term] id: FYPO:0003804 name: normal growth on non-fermentable carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing one or more non-fermentable substance(s) as the only carbon source(s)." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Also consider annotating to one or more terms that describe growth on a specific carbon source. synonym: "normal cell population growth on non-fermentable carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on non-fermentable carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-09-12T13:59:04Z [Term] id: FYPO:0003805 name: decreased cell population growth on non-fermentable carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing one or more non-fermentable substance(s) as the only carbon source(s)." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Also consider annotating to one or more terms that describe growth on a specific carbon source. synonym: "decreased growth on non-fermentable carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on non-fermentable carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on non-fermentable carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on gluconate carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2014-09-12T14:05:29Z [Term] id: FYPO:0003806 name: abolished cell population growth on non-fermentable carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing one or more non-fermentable substance(s) as the only carbon source(s)." [PomBase:mah] comment: Use this term for a population of cells that does not grow with a non-fermentable carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Also consider annotating to one or more terms that describe growth on a specific carbon source. synonym: "abolished growth on non-fermentable carbon source" BROAD [PomBase:mah] synonym: "abolished non-fermentable carbon source utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on non-fermentable carbon source" EXACT [PomBase:mah] synonym: "cell population growth on non-fermentable carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth is_a: FYPO:0003805 ! decreased cell population growth on non-fermentable carbon source created_by: midori creation_date: 2014-09-12T14:06:27Z [Term] id: FYPO:0003807 name: net-like mitochondrial morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitochondria form branched structures." [PMID:19373772] {comment="PMID:37540145"} synonym: "branched mitochondria" EXACT [] synonym: "branched mitochondria during vegetative growth" EXACT [PomBase:mah] synonym: "branched mitochondrion" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology created_by: midori creation_date: 2014-09-12T14:36:24Z [Term] id: FYPO:0003808 name: normal mitochondrial motility def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the movement of mitochondria is normal (i.e. indistinguishable from wild type). Mitochondria normally form tips that grow and shrink stochastically." [PMID:19373772, PomBase:mah] synonym: "normal mitochondrial dynamics" EXACT [PMID:19373772, PomBase:mah] synonym: "normal mitochondrial mobility" EXACT [PATO:0000004, PomBase:mah] synonym: "normal mitochondrial motility during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitochondrial motility during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear membrane morphology" NARROW [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-09-12T14:47:56Z [Term] id: FYPO:0003809 name: normal growth on latrunculin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing latrunculin A." [PomBase:mah] synonym: "normal cell population growth in presence of latrunculin A" EXACT [PomBase:mah] synonym: "normal cell population growth on latrunculin A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to latrunculin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on LAT-A" EXACT [PomBase:vw] synonym: "normal growth on LatA" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on latrunculin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-09-12T14:52:10Z [Term] id: FYPO:0003810 name: small fragmented mitochondria present in increased numbers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are smaller and more numerous than normal. Total mitochondrial volume is usually similar to normal." [PomBase:mah] synonym: "fragmented mitochondria" RELATED [PomBase:mah] synonym: "small mitochondria present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small mitochondria present in increased numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007193 ! small fragmented mitochondria is_a: FYPO:0007210 ! normal mitochondrial volume relationship: has_part FYPO:0007193 ! small fragmented mitochondria relationship: has_part FYPO:0007194 ! mitochondria present in increased numbers relationship: has_part FYPO:0007210 ! normal mitochondrial volume created_by: midori creation_date: 2014-09-12T14:56:05Z [Term] id: FYPO:0003811 name: asymmetric mitochondrial aggregation def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal with a cluster distal to only one side of the nucleus." [PomBase:mah] synonym: "asymmetric mitochondrial aggregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric mitochondrial aggregation during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondria localized to one cell end" RELATED [PomBase:vw] synonym: "monopolar intracellular mitochondrion distribution" RELATED [PomBase:mah] synonym: "monopolar intracellular mitochondrion localisation" RELATED [PomBase:mah] synonym: "monopolar intracellular mitochondrion localization" RELATED [PomBase:mah] synonym: "monopolar mitochondrial aggregation" RELATED [PomBase:mah] synonym: "monopolar mitochondrion distribution" RELATED [PomBase:mah] is_a: FYPO:0000895 ! mitochondrial aggregation created_by: midori creation_date: 2014-09-12T14:59:40Z [Term] id: FYPO:0003812 name: abnormal nucleosome positioning at stress response genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal near the promoter regions of genes that are expressed in response to stress. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome occupancy at stress response genes" RELATED [PomBase:mah, PomBase:vw] synonym: "abnormal nucleosome positioning at stress response genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleosome positioning at stress response genes during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing at stress response genes" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0007833 ! abnormal nucleosome positioning at protein-coding gene created_by: midori creation_date: 2014-09-12T15:35:00Z [Term] id: FYPO:0003813 name: normal nucleosome positioning at stress response genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is normal (i.e. indistinguishable from wild type) near the promoter regions of genes that are expressed in response to stress. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome occupancy at stress response genes" RELATED [PomBase:mah, PomBase:vw] synonym: "normal nucleosome positioning at stress response genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleosome positioning at stress response genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing at stress response genes" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000857 ! normal nucleosome positioning in euchromatin created_by: midori creation_date: 2014-09-12T15:36:34Z [Term] id: FYPO:0003814 name: abolished response to S-phase DNA damage checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) does not occur. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0072429, PomBase:mah] synonym: "abolished response to intra-S DNA damage checkpoint signaling" EXACT [GO:0072429, PomBase:mah] synonym: "abolished response to mitotic S-phase DNA damage checkpoint signaling" EXACT [PomBase:mah] synonym: "abolished response to S-phase DNA damage checkpoint signaling abolished" EXACT [PomBase:mah] synonym: "abolished response to S-phase DNA damage checkpoint signaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished response to S-phase DNA damage checkpoint signaling during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000007 ! abnormal S-phase DNA damage checkpoint relationship: has_output FYPO:0004241 ! decreased rate of DNA replication during cellular response to DNA damage created_by: midori creation_date: 2014-09-12T15:40:24Z [Term] id: FYPO:0003815 name: decreased response to S-phase DNA damage checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is decreased. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0072429, PomBase:mah] synonym: "decreased response to intra-S DNA damage checkpoint signaling" EXACT [PomBase:mah] synonym: "decreased response to mitotic S-phase DNA damage checkpoint signaling" EXACT [PomBase:mah] synonym: "decreased S-phase DNA damage checkpoint during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased S-phase DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "reduced response to intra-S DNA damage checkpoint signaling" EXACT [GO:0072429, PomBase:mah] is_a: FYPO:0000007 ! abnormal S-phase DNA damage checkpoint created_by: midori creation_date: 2014-09-12T15:49:47Z [Term] id: FYPO:0003816 name: growth auxotrophic for histidine or lysine def: "Auxotrophy in which a cell requires histidine or lysine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for histidine or lysine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for histidine or lysine during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for lysine or histidine" EXACT [PomBase:mah] synonym: "histidine or lysine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2014-09-12T15:55:36Z [Term] id: FYPO:0003817 name: abnormal 5'-3' DNA helicase activity def: "A molecular function phenotype in which the observed rate of 5'-3' DNA helicase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-09-12T16:00:55Z [Term] id: FYPO:0003818 name: abolished 5'-3' DNA helicase activity def: "A molecular function phenotype in which 5'-3' DNA helicase activity is absent." [PomBase:mah] synonym: "5'-3' DNA helicase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003817 ! abnormal 5'-3' DNA helicase activity created_by: midori creation_date: 2014-09-12T16:01:01Z [Term] id: FYPO:0003819 name: decreased 5'-3' DNA helicase activity def: "A molecular function phenotype in which the observed rate of 5'-3' DNA helicase activity is decreased." [PomBase:mah] synonym: "reduced 5'-3' DNA helicase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003817 ! abnormal 5'-3' DNA helicase activity created_by: midori creation_date: 2014-09-12T16:01:15Z [Term] id: FYPO:0003820 name: mitochondria present in decreased numbers during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer mitochondria than normal." [PomBase:mah] synonym: "decreased number of mitochondria during vegetative growth" EXACT [PomBase:mah] synonym: "fewer mitochondria during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondria present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondria present in reduced numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2014-09-12T16:10:08Z [Term] id: FYPO:0003821 name: abnormal ribonuclease activity def: "A molecular function phenotype in which the observed rate of a ribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-09-12T16:15:37Z [Term] id: FYPO:0003822 name: decreased ribonuclease activity def: "A molecular function phenotype in which the observed rate of a ribonuclease activity is decreased." [PomBase:mah] synonym: "reduced ribonuclease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003821 ! abnormal ribonuclease activity created_by: midori creation_date: 2014-09-12T16:15:49Z [Term] id: FYPO:0003823 name: septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to hydroxyurea def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, producing inviable daughter cells, and in which the septum forms in a position that partitions both nuclei into one compartment, when a cell is exposed to hydroxyurea. Cell separation may or may not be completed." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155) or its descendants, because these phenotypes often co-occur. synonym: "septation following abnormal chromosome segregation, with anucleate cell formation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septation following abnormal chromosome segregation, with anucleate cell formation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal chromosome segregation, with binucleate cell formation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0003166 ! monoseptate vegetative cell with binucleate and anucleate compartments created_by: midori creation_date: 2014-09-15T17:42:18Z [Term] id: FYPO:0003824 name: resistance to caffeine and rapamycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of caffeine and rapamycin than normal." [PomBase:mah] synonym: "resistance to caffeine and rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to caffeine and rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to caffeine and rapamycin in combination" EXACT [PomBase:vw] synonym: "resistant to caffeine and rapamycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-09-18T16:15:41Z [Term] id: FYPO:0003825 name: inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition." [PomBase:mah] comment: This phenotype may indicate that the cytokinesis after mitosis checkpoint is activated. Use this term when a cell goes through a cell cycle without cytokinesis taking place. In the subsequent cell cycle, the two nuclei can go through G1 and S phases but cannot undergo mitosis, so the nuclei remain in G2 phase. The cell does not contain a post-anaphase microtubule array. synonym: "inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation during vegetative growth" EXACT [PomBase:mah] synonym: "inviable binucleate aseptate cell with cell cycle arrest in mitotic G2 phase before cell separation" RELATED [PomBase:mah] synonym: "inviable binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cytokinesis" EXACT [PomBase:mah] synonym: "inviable binucleate aseptate cell with mitotic cell cycle arrest at G2/M phase transition before cell separation" EXACT [PomBase:mah] synonym: "inviable binucleate aseptate cell with mitotic G2/M phase transition arrest before cell separation" EXACT [] synonym: "inviable binucleate cell with mitotic cell cycle arrest at G2/M before division septum assembly" EXACT [GO:0000917] synonym: "inviable cell with mitotic G2/M arrest after failed cytokinesis" RELATED [PomBase:vw] synonym: "inviable cell with nuclear division arrest at G2/M without septation (normal cell length)" EXACT [PomBase:vw] synonym: "lethal; binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cell separation" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest at G2/M before cell separation with inviable binucleate aseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition is_a: FYPO:0005689 ! inviable binucleate aseptate cell with mitotic cell cycle arrest before cell separation created_by: midori creation_date: 2014-10-14T15:42:02Z [Term] id: FYPO:0003826 name: inviable elongated binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is elongated, has two nuclei but no septum, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition." [PomBase:mah] comment: This phenotype may indicate that the cytokinesis after mitosis checkpoint is activated. synonym: "inviable cell with nuclear division arrest at G2/M without septation (elongated cell)" EXACT [PomBase:vw] synonym: "inviable elongated binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cell separation" RELATED [PomBase:mah] synonym: "inviable elongated binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cell separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cytokinesis" EXACT [PomBase:mah] synonym: "inviable elongated binucleate aseptate cell with mitotic cell cycle arrest at mitotic G2/M phase transition before cell separation during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated binucleate aseptate cell with mitotic G2/M phase transition arrest before cell separation" EXACT [PomBase:vw] synonym: "inviable elongated binucleate cell with mitotic cell cycle arrest at G2/M before division septum assembly" EXACT [GO:0000917] synonym: "inviable elongated binucleate cell with mitotic cell cycle arrest before septation" EXACT [PomBase:mah] synonym: "lethal; elongated binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cell separation" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest at G2/M before cell separation with inviable elongated binucleate aseptate cell" EXACT [PomBase:vw] synonym: "mitotic G2/M arrest after failed cytokinesis, with inviable elongated cell" RELATED [PomBase:vw] is_a: FYPO:0003825 ! inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation is_a: FYPO:0004684 ! inviable elongated binucleate aseptate cell is_a: FYPO:0007702 ! inviable elongated cell with cell cycle arrest at mitotic G2/M phase transition created_by: midori creation_date: 2014-10-14T15:54:06Z [Term] id: FYPO:0003827 name: decreased ribosomal S6 protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the ribosomal small subunit protein S6 is decreased." [PMID:24463365, PomBase:mah] synonym: "decreased ribosomal S6 protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ribosome S6 phosphorylation during vegetative growth" EXACT [PomBase:al] synonym: "reduced ribosomal S6 protein phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-10-14T16:07:34Z [Term] id: FYPO:0003828 name: normal ribosomal S6 protein phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the ribosomal small subunit protein S6 is normal (i.e. indistinguishable from wild type)." [PMID:24463365, PomBase:mah] synonym: "normal ribosomal S6 protein phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal ribosome S6 phosphorylation during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-10-14T16:09:42Z [Term] id: FYPO:0003829 name: abolished mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation does not occur." [PomBase:mah] synonym: "abolished spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic spindle elongation abolished" EXACT [PomBase:mah] synonym: "mitotic spindle elongation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation relationship: has_output FYPO:0000732 ! short bipolar mitotic spindle created_by: midori creation_date: 2014-10-14T16:26:09Z [Term] id: FYPO:0003830 name: abnormal cytokinesis checkpoint def: "A cell cycle checkpoint phenotype in which the cytokinesis checkpoint of a mitotic cell cycle is abnormal. The cytokinesis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0044878, PomBase:mah] synonym: "abnormal cytokinesis after mitosis checkpoint" EXACT [GO:0044878] synonym: "abnormal cytokinesis checkpoint activation" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle cytokinesis checkpoint" EXACT [PomBase:mah] is_a: FYPO:0001704 ! abnormal mitotic cell cycle checkpoint created_by: midori creation_date: 2014-10-15T10:05:28Z [Term] id: FYPO:0003831 name: abolished response to cytokinesis checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the cytokinesis after mitosis checkpoint does not occur. The cytokinesis after mitosis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal." [GO:0044878, PomBase:mah] comment: May indicate that a cell cycle checkpoint is not activated under conditions that normally trigger checkpoint signaling and subsequent cell cycle arrest. synonym: "abolished cytokinesis after mitosis checkpoint" RELATED [PomBase:mah] synonym: "abolished cytokinesis checkpoint activation" RELATED [PomBase:mah] synonym: "abolished cytokinesis checkpoint arrest" RELATED [PomBase:mah] synonym: "abolished response to cytokinesis after mitosis checkpoint signaling" EXACT [PomBase:mah] synonym: "abolished response to mitotic cell cycle cytokinesis checkpoint signaling" EXACT [PomBase:mah] synonym: "cell cycle arrest resulting from cytokinesis checkpoint activation abolished" EXACT [PomBase:mah] is_a: FYPO:0003830 ! abnormal cytokinesis checkpoint created_by: midori creation_date: 2014-10-15T10:24:37Z [Term] id: FYPO:0003832 name: normal cell cycle def: "A cellular process phenotype in which cell cycle progression is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell cycle progression: normal" RELATED [SGD:phenotype_annotation] synonym: "normal cell cycle progression" EXACT [PomBase:mah] synonym: "normal cell-division cycle" EXACT [GO:0007049, PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2014-10-15T11:01:20Z [Term] id: FYPO:0003833 name: normal cell cycle phase def: "A cellular process phenotype in which a cell proceeds normally through a specific cell cycle phase. A cell cycle phase is any of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GO:0022403, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0003832 ! normal cell cycle created_by: midori creation_date: 2014-10-15T11:04:03Z [Term] id: FYPO:0003834 name: normal duration of meiotic interphase def: "A cell cycle phenotype in the duration of meiotic interphase, which begins after cytokinesis and ends when meiotic prophase begins, is normal (i.e. indistinguishable from wild type)." [GO:0051328, PomBase:mah] is_a: FYPO:0003833 ! normal cell cycle phase created_by: midori creation_date: 2014-10-15T11:05:28Z [Term] id: FYPO:0003835 name: normal horsetail movement def: "A cellular process phenotype in which horsetail movement is normal (i.e. indistinguishable from wild type). Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] comment: Consider also annotating to 'normal horsetail nucleus morphology' (FYPO:0003562). synonym: "normal dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989] synonym: "normal horsetail nuclear movement" EXACT [GO:0030989] is_a: FYPO:0001071 ! normal transport is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-10-15T11:08:48Z [Term] id: FYPO:0003836 name: decreased RNA polymerase II carboxy-terminal domain kinase activity def: "A molecular function phenotype in which the observed rate of RNA polymerase II carboxy-terminal domain kinase activity is decreased." [PomBase:mah] synonym: "reduced RNA polymerase II carboxy-terminal domain kinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2014-10-15T11:28:58Z [Term] id: FYPO:0003837 name: increased RNA polymerase II carboxy-terminal domain kinase activity def: "A molecular function phenotype in which the observed rate of RNA polymerase II carboxy-terminal domain kinase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2014-10-15T11:29:13Z [Term] id: FYPO:0003838 name: abolished actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction does not occur. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "abolished actomyosin contractile ring constriction" EXACT [PomBase:mah] synonym: "abolished actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "abolished cytokinesis with stable actinomyosin ring" RELATED [PomBase:vw] synonym: "abolished cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "abolished mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "abolished mitotic contractile ring contraction" EXACT [PomBase:mah] synonym: "actomyosin contractile ring contraction abolished" EXACT [PomBase:mah] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2014-10-15T13:54:53Z [Term] id: FYPO:0003839 name: abnormal protein localization to nucleolus during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abnormal during mitotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleolus during mitosis" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleolus during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to nucleolus during mitotic M phase" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2014-10-15T14:03:34Z [Term] id: FYPO:0003840 name: sensitive to carbendazim def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to carbendazim (mecarzole; MBC). Cells stop growing (and may die) at a concentration of carbendazim that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to carbendazim" EXACT [PomBase:mah] synonym: "sensitive to carbendazim during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to carbendazim during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to MBC" EXACT [CHEBI:3392, PomBase:mah] synonym: "sensitive to mecarzole" EXACT [CHEBI:3392] synonym: "sensitive to methyl benzimidazole-2-yl-carbamate" EXACT [CHEBI:3392] synonym: "sensitive to methylbenzylcarbamylate" EXACT [PMID:8247131] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-15T14:20:59Z [Term] id: FYPO:0003841 name: decreased protein localization to mitotic spindle midzone def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1902967, GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle midzone" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle midzone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to spindle midzone during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle midzone" EXACT [PomBase:mah] is_a: FYPO:0004883 ! abnormal protein localization to mitotic spindle midzone created_by: midori creation_date: 2014-10-16T11:19:29Z [Term] id: FYPO:0003842 name: inviable following spore germination, single cell division, abolished mitotic sister chromatid separation def: "A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division in which mitotic sister chromatid separation does not occur, and then dies." [PomBase:mah] synonym: "inviable germinated spore, single cell division, abolished mitotic sister chromatid separation" EXACT [PomBase:mah] synonym: "lethal; following spore germination, single cell division, abolished mitotic sister chromatid separation" EXACT [PomBase:mah] is_a: FYPO:0001946 ! abolished mitotic sister chromatid separation is_a: FYPO:0002280 ! inviable after spore germination, single cell division relationship: has_part FYPO:0001946 ! abolished mitotic sister chromatid separation created_by: midori creation_date: 2014-10-16T11:30:08Z [Term] id: FYPO:0003843 name: inviable following spore germination, single cell division, unequal chromosome segregation def: "A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division during which chromosomes segregate unequally, and then dies." [PomBase:mah] synonym: "inviable germinated spore, single cell division, unequal chromosome segregation" EXACT [PomBase:mah] synonym: "lethal; following spore germination, single cell division, unequal chromosome segregation" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0002280 ! inviable after spore germination, single cell division relationship: has_part FYPO:0003241 ! unequal mitotic sister chromatid segregation created_by: midori creation_date: 2014-10-16T11:37:02Z [Term] id: FYPO:0003844 name: abolished mitotic chromosome condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation does not occur over all or part of the chromosomes." [PomBase:mah] synonym: "abolished chromosome condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic chromosome condensation abolished" EXACT [PomBase:mah] is_a: FYPO:0000214 ! abnormal mitotic chromosome condensation is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2014-10-16T11:42:21Z [Term] id: FYPO:0003845 name: normal protein localization to prospore membrane def: "A transport phenotype in which protein localization to the prospore membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Encompasses both targeting of proteins to the prospore membrane where they are not normally found and decreased or no targeting of proteins normally found in the prospore membrane. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to prospore membrane" EXACT [PomBase:mah] synonym: "normal protein localization to forespore membrane" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2014-10-16T11:58:00Z [Term] id: FYPO:0003846 name: spores sensitive to acetone def: "A cell phenotype in which spores germinate to a lower extent than wild type following exposure to acetone." [PMID:24727291, PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2014-10-16T12:02:04Z [Term] id: FYPO:0003847 name: h- specific sterility def: "A cellular process phenotype in which conjugation does not occur in cells of the h- mating type." [PMID:24727291, PomBase:mah] synonym: "h--specific sterility" EXACT [PomBase:mah] synonym: "h-minus-specific mating defect" RELATED [PMID:24727291] synonym: "h-minus-specific sterility" EXACT [PomBase:mah] is_a: FYPO:0000280 ! sterile created_by: midori creation_date: 2014-10-16T12:03:33Z [Term] id: FYPO:0003848 name: sensitive to hydrazinocurcumin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrazinocurcumin. Cells stop growing (and may die) at a concentration of hydrazinocurcumin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hydrazinocurcumin" EXACT [PomBase:mah] synonym: "sensitive to hydrazinocurcumin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to hydrazinocurcumin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T13:30:30Z [Term] id: FYPO:0003849 name: normal growth on fluconazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing fluconazole." [PomBase:mah] synonym: "normal cell population growth in presence of fluconazole" EXACT [PomBase:mah] synonym: "normal cell population growth on fluconazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to fluconazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on fluconazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-10-16T14:32:42Z [Term] id: FYPO:0003850 name: normal growth on oligomycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing an oligomycin antibiotic." [PomBase:mah] synonym: "normal cell population growth in presence of oligomycin" EXACT [PomBase:mah] synonym: "normal cell population growth on oligomycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to oligomycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on oligomycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-10-16T14:33:29Z [Term] id: FYPO:0003851 name: normal growth on MTT def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)." [PomBase:mah] synonym: "normal cell population growth in presence of MTT" EXACT [PomBase:mah] synonym: "normal cell population growth on MTT" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to MTT" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide" EXACT [CHEBI:53233] synonym: "normal vegetative cell population growth on MTT" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-10-16T14:34:37Z [Term] id: FYPO:0003852 name: normal growth on FR901464 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing FR901464." [PomBase:mah] synonym: "normal cell population growth in presence of FR901464" EXACT [PomBase:mah] synonym: "normal cell population growth on FR901464" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to FR901464" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on FR901464" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-10-16T14:44:20Z [Term] id: FYPO:0003853 name: sensitive to fluconazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fluconazole. Cells stop growing (and may die) at a concentration of fluconazole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to fluconazole" EXACT [PomBase:mah] synonym: "sensitive to fluconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to fluconazole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:45:19Z [Term] id: FYPO:0003854 name: sensitive to oligomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to an oligomycin antibiotic. Cells stop growing (and may die) at a concentration of oligomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to oligomycin" EXACT [PomBase:mah] synonym: "sensitive to oligomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to oligomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:45:52Z [Term] id: FYPO:0003855 name: sensitive to MTT def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide). Cells stop growing (and may die) at a concentration of MTT that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to MTT" EXACT [PomBase:mah] synonym: "sensitive to 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide" EXACT [CHEBI:53233] synonym: "sensitive to MTT during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to MTT during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:46:36Z [Term] id: FYPO:0003856 name: sensitive to FR901464 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to FR901464. Cells stop growing (and may die) at a concentration of FR901464 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to FR901464" EXACT [PomBase:mah] synonym: "sensitive to FR901464 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to FR901464 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:48:53Z [Term] id: FYPO:0003857 name: sensitive to mevastatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mevastatin. Cells stop growing (and may die) at a concentration of mevastatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mevastatin" EXACT [PomBase:mah] synonym: "sensitive to compactin" EXACT [CHEBI:34848] synonym: "sensitive to mevastatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to mevastatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:49:41Z [Term] id: FYPO:0003858 name: sensitive to etoposide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to etoposide. Cells stop growing (and may die) at a concentration of etoposide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to etoposide" EXACT [PomBase:mah] synonym: "sensitive to etoposide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to etoposide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:51:08Z [Term] id: FYPO:0003859 name: sensitive to wortmannin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to wortmannin. Cells stop growing (and may die) at a concentration of wortmannin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to wortmannin" EXACT [PomBase:mah] synonym: "sensitive to wortmannin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to wortmannin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:51:47Z [Term] id: FYPO:0003860 name: resistance to miconazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of miconazole than normal." [PomBase:mah] synonym: "resistance to miconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to miconazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to miconazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-10-16T14:53:07Z [Term] id: FYPO:0003861 name: normal acidification of growth medium in stationary phase def: "A cell population phenotype in which the pH of a growth medium in which a cell population grows to stationary phase decreases to a normal (i.e. indistinguishable from wild type) extent." [PMID:23874875, PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2014-10-16T15:08:21Z [Term] id: FYPO:0003862 name: increased protein oxidation in stationary phase def: "A cellular process phenotype in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins, in cells in a population in stationary phase." [PMID:17986764, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "accumulation of carbonylated proteins in stationary phase" RELATED [PomBase:mah] synonym: "increased level of disulfides in stationary phase" RELATED [PomBase:al] synonym: "increased level of oxidised thiols in proteins in stationary phase" RELATED [PomBase:al] synonym: "increased level of oxidized protein thiols in stationary phase" RELATED [PomBase:mah] is_a: FYPO:0003863 ! increased protein oxidation created_by: midori creation_date: 2014-10-16T15:12:03Z [Term] id: FYPO:0003863 name: increased protein oxidation def: "A cellular process phenotype in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "accumulation of carbonylated proteins" RELATED [PomBase:mah] synonym: "increased level of disulfides" RELATED [PomBase:al] synonym: "increased level of oxidised thiols in proteins" RELATED [PomBase:al] synonym: "increased level of oxidized protein thiols" RELATED [PomBase:mah] is_a: FYPO:0002499 ! increased protein modification created_by: midori creation_date: 2014-10-16T15:14:29Z [Term] id: FYPO:0003864 name: decreased level of substance in cell during G0 def: "A cell phenotype in which the amount a specific substance measured in a cell is lower than normal when the cell is in G0 phase." [PomBase:mah] synonym: "decreased accumulation of substance in cell during G0" RELATED [PomBase:mah] synonym: "decreased level of substance in cell during cell quiescence" EXACT [PomBase:mah] synonym: "decreased level of substance in cell during quiescence" EXACT [PomBase:mah] synonym: "decreased substance level during G0" EXACT [PomBase:vw] synonym: "reduced level of substance in cell during G0" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2014-10-16T15:57:29Z [Term] id: FYPO:0003865 name: decreased protein level during G0 def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal when the cell is in G0 phase. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability as well as changes in translation. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during G0" RELATED [PomBase:mah] synonym: "decreased protein level during cell quiescence" EXACT [PomBase:mah] synonym: "decreased protein level during quiescence" EXACT [PomBase:mah] synonym: "reduced protein level during G0" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level is_a: FYPO:0003864 ! decreased level of substance in cell during G0 created_by: midori creation_date: 2014-10-16T16:00:08Z [Term] id: FYPO:0003866 name: increased protein level during G0 def: "A cell phenotype in which the amount of protein measured in a cell when the cell is in G0 phase is higher than normal. Total protein or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability as well as changes in translation. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during G0" RELATED [PomBase:mah] synonym: "increased protein level during cell quiescence" EXACT [PomBase:mah] synonym: "increased protein level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0000836 ! increased protein level is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2014-10-16T16:00:59Z [Term] id: FYPO:0003867 name: increased level of ubiquitinated protein in cell during G0 def: "A cell phenotype in which the amount of ubiquitinated protein measured in the cell is higher than normal when the cell is in G0 phase. Total protein or a specific protein may be affected." [PMID:20133687, PomBase:mah] comment: Consider also annotating to 'increased protein ubiquitination' (FYPO:0002082) if the experiment directly assays the ubiquitination reaction(s). synonym: "increased accumulation of ubiquitinated protein in cell during G0" RELATED [PomBase:al] synonym: "increased level of ubiquitinated protein in cell during cell quiescence" EXACT [PomBase:mah] synonym: "increased level of ubiquitinated protein in cell during quiescence" EXACT [PomBase:mah] synonym: "increased ubiquitinated protein level during G0" EXACT [PomBase:mah] is_a: FYPO:0003866 ! increased protein level during G0 created_by: midori creation_date: 2014-10-16T16:02:23Z [Term] id: FYPO:0003868 name: mitochondria present in decreased numbers during G0 def: "A physical cellular phenotype in which a cell contains fewer mitochondria than normal during G0 phase." [PMID:20133687, PomBase:mah] synonym: "decreased number of mitochondria during G0" EXACT [PomBase:mah] synonym: "fewer mitochondria during G0" EXACT [PomBase:mah] synonym: "mitochondria present in decreased numbers during cell quiescence" EXACT [PomBase:mah] synonym: "mitochondria present in decreased numbers during quiescence" EXACT [PomBase:mah] synonym: "mitochondria present in reduced numbers during G0" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2014-10-16T16:08:56Z [Term] id: FYPO:0003869 name: increased level of hydrogen peroxide-induced proteins during G0 def: "A cell phenotype observed in which the amount of protein encoded by genes normally induced by exposure to hydrogen peroxide measured in a cell is higher than normal when the cell is in G0 phase." [PMID:20133687, PomBase:mah] synonym: "increased level of H2O2-induced proteins during G0" EXACT [PomBase:mah] synonym: "increased level of hydrogen peroxide-induced proteins during cell quiescence" EXACT [PomBase:mah] synonym: "increased level of hydrogen peroxide-induced proteins during quiescence" EXACT [PomBase:mah] synonym: "increased level of proteins expressed during cellular response to hydrogen peroxide during G0" EXACT [PomBase:mah] synonym: "increased level of proteins induced by hydrogen peroxide during G0" EXACT [PomBase:mah] synonym: "increased protein level of genes (normally) induced during H2O2 stress during G0" EXACT [PomBase:al] is_a: FYPO:0003866 ! increased protein level during G0 created_by: midori creation_date: 2014-10-16T16:17:59Z [Term] id: FYPO:0003870 name: increased level of cadmium-induced proteins during G0 def: "A cell phenotype observed in which the amount of protein encoded by genes normally induced by exposure to cadmium ions measured in a cell is higher than normal when the cell is in G0 phase." [PMID:20133687, PomBase:mah] synonym: "increased level of cadmium-induced proteins during cell quiescence" EXACT [PomBase:mah] synonym: "increased level of cadmium-induced proteins during quiescence" EXACT [PomBase:mah] synonym: "increased level of proteins expressed during cellular response to cadmium during G0" EXACT [PomBase:mah] synonym: "increased level of proteins induced by cadmium during G0" EXACT [PomBase:mah] synonym: "increased protein level of genes (normally) induced during cadmium stress during G0" EXACT [PomBase:al] is_a: FYPO:0003866 ! increased protein level during G0 created_by: midori creation_date: 2014-10-16T16:21:36Z [Term] id: FYPO:0003871 name: abnormal chromatin organization during G0 def: "A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is in G0 phase. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PMID:20133687, PomBase:mah] synonym: "abnormal chromatin organisation during G0" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during quiescence" EXACT [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2014-10-16T16:23:04Z [Term] id: FYPO:0003872 name: increased glutathione level during G0 def: "A cell phenotype in which the amount of glutathione measured in a cell is higher than normal when the cell is in G0 phase." [PMID:20133687, PomBase:mah] synonym: "increased glutathione accumulation during G0" RELATED [PomBase:mah] synonym: "increased glutathione level during cell quiescence" EXACT [PomBase:mah] synonym: "increased glutathione level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2014-10-16T16:24:07Z [Term] id: FYPO:0003873 name: increased reactive oxygen species level during G0 def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the cell is in G0 phase." [PMID:20133687, PomBase:mah] synonym: "increased cellular ROS level during G0" EXACT [PomBase:mah] synonym: "increased reactive oxygen species accumulation during G0" RELATED [PomBase:mah] synonym: "increased reactive oxygen species level during cell quiescence" EXACT [PomBase:mah] synonym: "increased reactive oxygen species level during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002142 ! altered cellular reactive oxygen species level is_a: FYPO:0002949 ! increased level of substance in cell during G0 created_by: midori creation_date: 2014-10-16T16:31:04Z [Term] id: FYPO:0003874 name: abnormal dense body present in nucleus during G0 def: "A physical cellular phenotype observed in G0 phase in which the nucleus contains one or more structures of great electron density that are not found in wild type cells." [PMID:20133687, PomBase:mah] synonym: "abnormal dense body present in nucleus during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal dense body present in nucleus during quiescence" EXACT [PomBase:mah] is_a: FYPO:0002403 ! abnormal nucleus created_by: midori creation_date: 2014-10-16T16:35:52Z [Term] id: FYPO:0003875 name: inviable elongated cell with mitotic G2/M transition delay and cell cycle arrest in M phase def: "A cell phenotype in which a cell is elongated and inviable, and prior to death the cell undergoes a mitotic G2/M transition that begins later than normal, followed by cell cycle arrest in M phase." [PMID:114458769, PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell with mitotic G2/M transition delay and cell cycle arrest in M phase" EXACT [PomBase:mah] synonym: "elongated inviable cell with mitotic G2/M transition delay and cell cycle arrest in M phase during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable cell with mitotic G2/M transition delay and M phase arrest" EXACT [PomBase:vw] synonym: "inviable elongated cell with G2/M transition delay and cell cycle arrest in M phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated cell with mitotic G2/M transition delay and M phase arrest" EXACT [PomBase:vw] synonym: "lethal; elongated cell with mitotic G2/M transition delay and cell cycle arrest in M phase" EXACT [PomBase:mah] synonym: "long inviable cell with mitotic G2/M transition delay and cell cycle arrest in M phase" EXACT [PomBase:vw] is_a: FYPO:0000012 ! mitotic G2/M phase transition delay is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase is_a: FYPO:0001490 ! inviable elongated vegetative cell relationship: has_part FYPO:0000012 ! mitotic G2/M phase transition delay relationship: has_part FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2014-10-21T12:04:07Z [Term] id: FYPO:0003876 name: normal cytokinesis checkpoint def: "A cell cycle checkpoint phenotype in which the cytokinesis after mitosis checkpoint of a mitotic cell cycle is normal (i.e. indistinguishable from wild type). The cytokinesis after mitosis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle." [GO:0044878, PomBase:mah] synonym: "normal cytokinesis after mitosis checkpoint" EXACT [GO:0044878] synonym: "normal cytokinesis checkpoint activation" RELATED [PomBase:mah] synonym: "normal mitotic cell cycle cytokinesis checkpoint" EXACT [PomBase:mah] synonym: "normally activated cytokinesis checkpoint" RELATED [PomBase:vw] is_a: FYPO:0001703 ! normal mitotic cell cycle checkpoint created_by: midori creation_date: 2014-10-21T12:15:43Z [Term] id: FYPO:0003877 name: single cell division prior to G0 entry def: "A cellular process phenotype in which a cell undergoes one round of cell division, instead of the normal two rounds, prior to entering quiescence (G0)." [PMID:20133687, PomBase:al, PomBase:mah] synonym: "G0 to G1 transition after single cell division" EXACT [PomBase:mah] synonym: "one cell division prior to G0 entry" EXACT [PomBase:al] synonym: "single cell division prior to cell quiescence entry" EXACT [PomBase:mah] synonym: "single cell division prior to quiescence entry" EXACT [PomBase:mah] is_a: FYPO:0000427 ! abnormal G1 to G0 transition created_by: midori creation_date: 2014-10-21T12:22:15Z [Term] id: FYPO:0003878 name: sensitive to monensin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to monensin. Cells stop growing (and may die) at a concentration of monensin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to monensin" EXACT [PomBase:mah] synonym: "sensitive to monensin A" NARROW [CHEBI:27617] synonym: "sensitive to monensin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to monensin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-21T12:25:35Z [Term] id: FYPO:0003879 name: delayed onset of age-related vacuolar changes def: "A cell phenotype in which changes in vacuolar morphology or function associated with cell aging begin later than normal. As cells age, vacuoles become fragmented and vacuolar acidity decreases. In a mutant, these changes may occur to a lesser extent as well as later than in wild type." [PMID:23521895, PomBase:mah] synonym: "delayed age-related vacuolar changes" EXACT [PomBase:mah] synonym: "delayed onset of age-related vacuole changes" EXACT [PomBase:mah] synonym: "delayed onset of vacuolar changes during cell aging" EXACT [PomBase:mah] synonym: "increased vacuolar maintenance in aged cells" RELATED [PomBase:al] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2014-10-21T13:21:51Z [Term] id: FYPO:0003881 name: mtDNA absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial DNA measured in a cell is too low to detect." [PomBase:mah] synonym: "absent mtDNA" EXACT [PomBase:vw] synonym: "mitochondrial DNA absent from cell" EXACT [PMID:2894829] synonym: "mtDNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mtDNA absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0003769 ! decreased cellular mtDNA level created_by: midori creation_date: 2014-10-21T13:43:19Z [Term] id: FYPO:0003882 name: increased cyclosporin A binding def: "A molecular function phenotype in which occurrence of cyclosporin A binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds cyclosporin A more than wild type, or that a mutation in one gene increases cyclosporin A binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-10-21T13:58:50Z [Term] id: FYPO:0003883 name: increased sanglifehrin A binding def: "A molecular function phenotype in which occurrence of sanglifehrin A binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds sanglifehrin A more than wild type, or that a mutation in one gene increases sanglifehrin A binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-10-21T13:59:37Z [Term] id: FYPO:0003884 name: abnormal NAD(P)H oxidase activity def: "A molecular function phenotype in which the observed rate of NAD(P)H oxidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-10-21T14:05:49Z [Term] id: FYPO:0003885 name: decreased NAD(P)H oxidase activity def: "A molecular function phenotype in which the observed rate of NAD(P)H oxidase activity is decreased." [PomBase:mah] synonym: "reduced NAD(P)H oxidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003884 ! abnormal NAD(P)H oxidase activity created_by: midori creation_date: 2014-10-21T14:05:54Z [Term] id: FYPO:0003886 name: abnormal endocytosis def: "A cellular process phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [GO:0006897, PomBase:mah] synonym: "abnormal actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "abnormal protein internalization" NARROW [PomBase:mah] synonym: "endocytosis defects" EXACT [PomBase:mah] synonym: "endocytosis: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2014-10-21T14:16:25Z [Term] id: FYPO:0003887 name: abolished endocytosis during meiotic cell cycle def: "A cellular process phenotype in which endocytosis does not occur during a meiotic cell cycle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "abolished actin-mediated endocytosis during meiotic cell cycle" EXACT [PomBase:vw] synonym: "abolished protein internalization during meiotic cell cycle" NARROW [PomBase:vw] synonym: "absent endocytosis during meiotic cell cycle" EXACT [PomBase:mah] synonym: "endocytosis abolished during meiotic cell cycle" EXACT [PomBase:mah] synonym: "endocytosis: absent during meiotic cell cycle" RELATED [SGD:phenotype_annotation] is_a: FYPO:0003886 ! abnormal endocytosis is_a: FYPO:0006393 ! localization phenotype during meiotic cell cycle created_by: midori creation_date: 2014-10-21T14:17:02Z [Term] id: FYPO:0003888 name: increased cell wall thickness at new end during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thicker than normal at the new end of the cell." [PMID:10547441, PomBase:mah] synonym: "increased cell wall thickness at new end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "thickened cell wall at new end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001035 ! increased cell wall thickness during vegetative growth created_by: midori creation_date: 2014-10-21T14:27:56Z [Term] id: FYPO:0003889 name: decreased cell wall thickness at old end during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thinner than normal at the old end of the cell." [PMID:10547441, PomBase:mah] synonym: "decreased cell wall thickness at growing end during vegetative growth" RELATED [PomBase:vw] synonym: "decreased cell wall thickness at old end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced cell wall thickness at old end during vegetative growth" EXACT [PomBase:mah] synonym: "thin cell wall at old end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006746 ! decreased cell wall thickness at cell tip during vegetative growth created_by: midori creation_date: 2014-10-21T14:29:12Z [Term] id: FYPO:0003890 name: abnormal primary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis is abnormal. Primary cell septum biogenesis results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of the primary cell septum during cytokinesis." [PomBase:mah] synonym: "abnormal primary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal primary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal primary cell septum formation" RELATED [PomBase:mah] synonym: "abnormal primary cell septum synthesis" RELATED [PomBase:mah] synonym: "abnormal primary septum biogenesis" EXACT [PomBase:mah] is_a: FYPO:0000117 ! abnormal septum assembly created_by: midori creation_date: 2014-10-21T14:30:09Z [Term] id: FYPO:0003891 name: normal intragenic meiotic recombination def: "A cellular process phenotype in which the occurrence of intragenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intragenic meiotic recombination can result in gene conversion events." [PMID:11104907, PomBase:mah] synonym: "normal meiotic intragenic recombination" EXACT [PomBase:al] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-10-21T14:35:38Z [Term] id: FYPO:0003892 name: abnormal error-prone translesion synthesis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which error-prone translesion synthesis is abnormal. Error-prone translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication." [GO:0042276, PomBase:mah] synonym: "abnormal error-prone translesion synthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal error-prone translesion synthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-10-21T15:13:48Z [Term] id: FYPO:0003893 name: abolished incorporation of ATP opposite 8-oxo-dG def: "A cellular process phenotype in which the insertion of ATP opposite an 8-oxo-7,8-dihydroguanosine (8oxodG) residue in DNA does not occur. Normally, if a guanosine residue is damaged to form 8oxodG, ATP can be misincorporated into the opposite strand to form an 8oxodG:AMP mispair that is subsequently removed." [PMID:25106870, PomBase:mah] synonym: "abolished incorporation of ATP opposite 8-oxo-7,8-dihydroguanosine" EXACT [PomBase:mah] synonym: "abolished insertion of ATP opposite 8-oxo-dG" EXACT [PomBase:mah] synonym: "incorporation of ATP opposite 8-oxo-dG abolished" EXACT [PomBase:mah] is_a: FYPO:0003892 ! abnormal error-prone translesion synthesis created_by: midori creation_date: 2014-10-21T15:15:32Z [Term] id: FYPO:0003894 name: sensitive to rotenone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rotenone. Cells stop growing (and may die) at a concentration of rotenone that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to rotenone" EXACT [PomBase:mah] synonym: "sensitive to rotenone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to rotenone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-21T15:24:06Z [Term] id: FYPO:0003895 name: resistance to rotenone def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of rotenone than normal." [PomBase:mah] synonym: "resistance to rotenone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to rotenone during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to rotenone" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-10-21T15:25:09Z [Term] id: FYPO:0003896 name: normal mitochondrial morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitochondrion is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that an abnormal mitochondrion organization process may, but does not necessarily, result in abnormal mitochondrial morphology. synonym: "normal mitochondrial morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitochondrial tubular network morphology" EXACT [PMID:20655879, PomBase:al] is_a: FYPO:0006034 ! normal mitochondrion created_by: midori creation_date: 2014-10-21T15:37:07Z [Term] id: FYPO:0003897 name: mitochondrial aggregation during cellular response to reactive oxygen species def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal during a cellular response to reactive oxygen species." [PomBase:mah] synonym: "aggregated mitochondria during cellular response to reactive oxygen species" NARROW [PomBase:vw] synonym: "mitochondrial aggregation at cell end during cellular response to reactive oxygen species" RELATED [PomBase:mah] synonym: "mitochondrial aggregation at cell tip during cellular response to reactive oxygen species" RELATED [PomBase:mah] synonym: "mitochondrial aggregation during cellular response to reactive oxygen species during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial aggregation during cellular response to reactive oxygen species during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial aggregation during cellular response to ROS" EXACT [GO:0034614] is_a: FYPO:0000895 ! mitochondrial aggregation created_by: midori creation_date: 2014-10-21T15:51:32Z [Term] id: FYPO:0003898 name: normal growth on glycerol/ethanol carbon source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glycerol and ethanol as the carbon sources." [PomBase:mah] synonym: "normal cell population growth on glycerol/ethanol carbon source" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on glycerol/ethanol carbon source" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-10-21T15:56:28Z [Term] id: FYPO:0003899 name: abnormal triphosphatase activity def: "A molecular function phenotype in which the observed rate of a triphosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-10-21T15:58:12Z [Term] id: FYPO:0003900 name: decreased triphosphatase activity def: "A molecular function phenotype in which the observed rate of a triphosphatase activity is decreased." [PomBase:mah] synonym: "reduced triphosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003899 ! abnormal triphosphatase activity created_by: midori creation_date: 2014-10-21T15:58:17Z [Term] id: FYPO:0003901 name: normal triphosphatase activity def: "A molecular function phenotype in which the observed rate of a triphosphatase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-10-21T15:58:37Z [Term] id: FYPO:0003902 name: resistance to etoposide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of etoposide than normal." [PomBase:mah] synonym: "resistance to etoposide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to etoposide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to etoposide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-10-21T16:02:09Z [Term] id: FYPO:0003903 name: loss of viability at low temperature def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are grown at a temperature lower than standard." [PomBase:mah] comment: For S. pombe, low temperature usually means below 25 degrees C. Use this term to annotate experiments in which a culture is grown at low temperature, and then the number of cells viable enough to form a colony upon return to standard or high temperature is measured and compared to wild type. synonym: "decreased viability at low temperature" EXACT [PomBase:mah] synonym: "loss of cell population viability at low temperature" EXACT [PomBase:mah] synonym: "loss of viability at restrictive temperature" RELATED [PomBase:mah] synonym: "reduced viability at low temperature" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2014-10-22T10:30:48Z [Term] id: FYPO:0003904 name: normal plasma membrane morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the plasma membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal plasma membrane morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal plasma membrane morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-10-22T10:34:28Z [Term] id: FYPO:0003905 name: normal meiotic spindle pole body morphology during meiosis II def: "A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is normal (i.e. indistinguishable from wild type) during the second meiotic nuclear division." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "normal meiotic SPB morphology during meiosis II" EXACT [PomBase:mah] synonym: "normal meiotic spindle pole body structure during meiosis II" NARROW [PomBase:mah] synonym: "normal spindle pole body morphology during meiosis II" EXACT [PomBase:mah] synonym: "normal spindle pole body morphology during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2014-10-22T10:37:14Z [Term] id: FYPO:0003906 name: normal growth on bleomycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing bleomycin." [PomBase:mah] synonym: "normal cell population growth in presence of bleomycin" EXACT [PomBase:mah] synonym: "normal cell population growth on bleomycin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to bleomycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on bleomycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-10-22T10:57:17Z [Term] id: FYPO:0003907 name: sensitive to okadaic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to okadaic acid. Cells stop growing (and may die) at a concentration of okadaic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to okadaic acid" EXACT [PomBase:mah] synonym: "sensitive to okadaic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to okadaic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-10-22T11:00:34Z [Term] id: FYPO:0003908 name: increased stress response gene antisense RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of genes that are expressed in response to stress measured in a cell is greater than normal. All stress-responsive genes, or a specific subset of such genes, may be affected." [PomBase:mah] synonym: "increased antisense RNA level at stress response genes" RELATED [PomBase:mah] synonym: "increased level of stress response gene antisense transcripts" EXACT [PomBase:al] synonym: "increased stress response gene antisense RNA accumulation" RELATED [PomBase:mah] synonym: "increased stress response gene antisense RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased stress response gene antisense RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased stress response gene antisense transcript level" EXACT [PomBase:vw] is_a: FYPO:0003557 ! increased antisense RNA level created_by: midori creation_date: 2014-10-22T11:40:02Z [Term] id: FYPO:0003909 name: increased nucleosome occupancy at CRE site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing CRE sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:25122751, PomBase:mah] synonym: "increased nucleosome occupancy at CRE site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy at CRE site during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003812 ! abnormal nucleosome positioning at stress response genes created_by: midori creation_date: 2014-10-22T11:48:22Z [Term] id: FYPO:0003910 name: abolished VLP localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of retrotransposon nucleocapsid complexes (also called virus-like particles, VLPs) to the nucleus is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished retrotransposon nucleocapsid localization to nucleus during vegetative growth" EXACT [GO:0000943] synonym: "abolished virus-like particle localization to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "abolished VLP localisation to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "abolished VLP localization in nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "abolished VLP localization to nucleus during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] synonym: "VLP localization to nucleus abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: midori creation_date: 2014-10-22T13:59:34Z [Term] id: FYPO:0003911 name: UGA suppression def: "A translation phenotype in which a tRNA pairs with mRNA at the stop codon UGA, and incorporates an amino acid residue into the nascent polypeptide." [PomBase:mah] synonym: "opal suppression" EXACT [PomBase:mah] synonym: "opal suppressor" EXACT [PomBase:mah] synonym: "UGA suppressor" EXACT [PomBase:mah] is_a: FYPO:0001797 ! abnormal translation created_by: midori creation_date: 2014-10-22T14:37:43Z [Term] id: FYPO:0003912 name: decreased double-strand break repair via homologous recombination def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair via homologous recombination occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased double-strand break repair via homologous recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased double-strand break repair via homologous recombination during vegetative growth" EXACT [PomBase:mah] synonym: "reduced double-strand break repair via homologous recombination" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2014-10-22T14:54:20Z [Term] id: FYPO:0003913 name: decreased minichromosome loss during vegetative growth def: "A cell phenotype in which minichromosomes are lost at a lower frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PomBase:mah] comment: Note that in budding yeast, a plasmid loss phenotype is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. In fission yeast, a minichromosome is a large portion of a chromosome, usually about half of chromosome 3, that replicates and segregates autonomously. For smaller autonomously replicating and segregating constructs, consider 'decreased plasmid loss' (FYPO:0001311). synonym: "decreased minichromosome loss during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced minichromosome loss during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2014-10-22T14:55:34Z [Term] id: FYPO:0003914 name: increased protein level in stationary phase def: "A cell phenotype in which the amount of protein measured in a cell is higher than normal when the population in which the cell is found is in stationary phase. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation in stationary phase" RELATED [PomBase:mah] is_a: FYPO:0000836 ! increased protein level created_by: midori creation_date: 2014-10-22T15:05:22Z [Term] id: FYPO:0003915 name: decreased mitochondrial protein level def: "A cell phenotype in which the amount of protein measured in the mitochondrion is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased level of mitochondrial proteins" EXACT [PomBase:al] synonym: "decreased mitochondrial protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial protein level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in mitochondrion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitochondrial protein level" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0004957 ! altered level of substance in mitochondrion created_by: midori creation_date: 2014-10-22T17:27:17Z [Term] id: FYPO:0003916 name: abnormal nonsense-mediated decay def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is abnormal." [PomBase:mah] synonym: "abnormal NMD" EXACT [PomBase:mah] synonym: "abnormal nonsense-mediated decay during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nonsense-mediated decay during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" EXACT [GO:0000184] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2014-10-22T17:30:05Z [Term] id: FYPO:0003917 name: decreased nonsense-mediated decay def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is decreased." [PomBase:mah] synonym: "decreased NMD" EXACT [PomBase:mah] synonym: "decreased nonsense-mediated decay during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nonsense-mediated decay during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" EXACT [GO:0000184] synonym: "reduced nonsense-mediated decay" EXACT [PomBase:mah] is_a: FYPO:0003916 ! abnormal nonsense-mediated decay created_by: midori creation_date: 2014-10-22T17:30:30Z [Term] id: FYPO:0003918 name: abolished nonsense-mediated decay def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations does not occur." [PomBase:mah] synonym: "abolished NMD" EXACT [PomBase:mah] synonym: "abolished nonsense-mediated decay during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished nonsense-mediated decay during vegetative growth" EXACT [PomBase:mah] synonym: "abolished nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" EXACT [GO:0000184] synonym: "nonsense-mediated decay abolished" EXACT [PomBase:mah] is_a: FYPO:0003916 ! abnormal nonsense-mediated decay created_by: midori creation_date: 2014-10-22T17:31:00Z [Term] id: FYPO:0003919 name: abolished protein localization to medial cortical node def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "abolished protein localization to cortical medial dot" EXACT [PomBase:mah] synonym: "abolished protein localization to cytokinetic nodes" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortical nodes" EXACT [PomBase:mah] synonym: "abolished protein recruitment to medial cortical node" RELATED [PomBase:vw] synonym: "protein localization to medial cortical node abolished" EXACT [PomBase:mah] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node created_by: midori creation_date: 2014-10-23T15:16:21Z [Term] id: FYPO:0003920 name: increased replication fork arrest at mating-type locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus occurs to a greater extent than normal." [PomBase:mah] synonym: "increased replication fork arrest at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork arrest at mating-type locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003083 ! abnormal replication fork arrest at mating-type locus created_by: midori creation_date: 2014-10-23T15:35:55Z [Term] id: FYPO:0003921 name: increased replication fork arrest at rDNA repeats def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic rDNA repeat spacer occurs to a greater extent than normal." [PomBase:mah] synonym: "increased replication fork arrest at rDNA repeats during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork arrest at rDNA repeats during vegetative growth" EXACT [PomBase:mah] synonym: "increased replication fork arrest at ribosomal DNA repeats" EXACT [PomBase:mah] is_a: FYPO:0003089 ! abnormal replication fork arrest at rDNA repeats created_by: midori creation_date: 2014-10-23T15:36:58Z [Term] id: FYPO:0003922 name: increased replication fork arrest at tRNA locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic tRNA transcription unit occurs to a greater extent than normal." [PomBase:mah] synonym: "increased replication fork arrest at tRNA genes" EXACT [PomBase:mah] synonym: "increased replication fork arrest at tRNA locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork arrest at tRNA locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003088 ! abnormal replication fork arrest created_by: midori creation_date: 2014-10-23T15:37:50Z [Term] id: FYPO:0003923 name: decreased rate of mitotic DNA replication elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is decreased." [PomBase:mah] synonym: "decreased rate of DNA replication elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of DNA strand elongation involved in mitotic DNA replication" EXACT [PomBase:mah] synonym: "decreased rate of DNA strand elongation involved in nuclear cell cycle DNA replication" EXACT [GO:1902319] synonym: "decreased rate of mitotic DNA replication elongation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of mitotic DNA replication elongation" EXACT [PomBase:mah] is_a: FYPO:0001981 ! decreased rate of DNA replication is_a: FYPO:0006730 ! abnormal mitotic DNA replication elongation created_by: midori creation_date: 2014-10-23T15:45:04Z [Term] id: FYPO:0003924 name: increased DNA damage at stalled replication fork def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured at arrested replication forks in a cell is greater than normal. The number, extent, or both of damage sites may be increased." [PomBase:mah] synonym: "increased DNA damage at arrested replication fork" EXACT [PomBase:mah] synonym: "increased DNA damage at stalled replication fork during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA damage at stalled replication fork during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of DNA lesions at stalled replication forks during vegetative growth" RELATED [PomBase:al] is_a: FYPO:0003547 ! increased DNA damage during vegetative growth created_by: midori creation_date: 2014-10-23T15:47:13Z [Term] id: FYPO:0003925 name: decreased rate of mitotic DNA replication elongation at highly transcribed RNA polymerase II genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is decreased in regions where RNA polymerase II actively transcribes genes." [PMID:22426534, PomBase:mah] synonym: "decreased rate of DNA replication elongation at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of DNA strand elongation at highly transcribed RNA polymerase II genes involved in mitotic DNA replication" EXACT [PomBase:mah] synonym: "decreased rate of DNA strand elongation at highly transcribed RNA polymerase II genes involved in nuclear cell cycle DNA replication" EXACT [GO:1902319] synonym: "decreased rate of mitotic DNA replication elongation at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of mitotic DNA replication elongation at highly transcribed RNA polymerase II genes" EXACT [PomBase:mah] is_a: FYPO:0003923 ! decreased rate of mitotic DNA replication elongation created_by: midori creation_date: 2014-10-23T15:49:45Z [Term] id: FYPO:0003926 name: increased number of converged replication forks def: "A cell phenotype in which a cell contains a larger number of sites where replication forks have converged than normal. Additional converged forks are usually detected at sites that are normally replicated unidirectionally." [PMID:22426534, PomBase:mah] synonym: "increased converged forks" EXACT [PMID:22426534] synonym: "increased number of converged replication forks during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of converged replication forks during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2014-10-28T16:14:25Z [Term] id: FYPO:0003927 name: decreased population viability in presence of persistent double-strand breaks def: "A cell population phenotype in which a smaller than normal proportion of cells in the population is viable when double-strand breaks in DNA are continually made (for example, by constitutive expression of a nuclease)." [PMID:22093869, PomBase:mah] comment: This phenotype is commonly assayed by continuous expression of the HO endonuclease. synonym: "decreased frequency of HO survivors" NARROW [PMID:22093869] synonym: "decreased population viability in presence of nuclease" RELATED [PomBase:mah] synonym: "reduced population viability in presence of persistent double-strand breaks" EXACT [PomBase:mah] is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2014-10-28T16:27:07Z [Term] id: FYPO:0003928 name: altered double-strand break repair junction in presence of persistent double-strand breaks def: "A cell phenotype in which the repair of double-strand breaks in DNA that are continually made (for example, by constitutive expression of a nuclease) results in repair junctions that differ from wild type." [PMID:22093869, PomBase:mah] comment: This phenotype is commonly assayed using continuous expression of the HO endonuclease, and in mutant cells that survive constitutive DNA cleavage by HO, break repair patterns differ from those in wild type HO survivors. synonym: "abnormal double-strand break repair resulting in formation of altered repair junction" EXACT [PomBase:mah] synonym: "altered pattern of repair junctions in HO survivors" NARROW [PMID:22093869] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2014-10-28T16:28:47Z [Term] id: FYPO:0003929 name: spores sensitive to ionizing radiation def: "A cell phenotype in which spores germinate to a lower extent than wild type following exposure to ionizing radiation." [PMID:24847916, PomBase:mah] synonym: "sensitive to ionizing radiation in the spore phase" EXACT [PMID:24847916] synonym: "spores sensitive to IR" EXACT [PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2014-10-28T16:33:39Z [Term] id: FYPO:0003930 name: decreased protein level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-10-28T16:36:52Z [Term] id: FYPO:0003931 name: inviable aseptate vegetative cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has no septum and is inviable." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "lethal; aseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000949 ! aseptate is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000949 ! aseptate relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2014-10-28T16:42:24Z [Term] id: FYPO:0003932 name: normal nuclear 5'-3' exonucleolytic mRNA catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an exonucleolytic RNA catabolic process that proceeds in the 5' to 3' direction to degrade mRNA encoded in the nucleus is normal (i.e. indistinguishable from wild type)." [GO:0034428, PomBase:mah] synonym: "normal 5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process" EXACT [GO:0034428] synonym: "normal nuclear 5'-3' exonucleolytic mRNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear 5'-3' exonucleolytic mRNA catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'" EXACT [GO:0034428] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T10:34:30Z [Term] id: FYPO:0003933 name: decreased nuclear 5'-3' exonucleolytic mRNA catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an exonucleolytic RNA catabolic process that proceeds in the 5' to 3' direction to degrade mRNA encoded in the nucleus is decreased." [GO:0034428, PomBase:mah] synonym: "decreased 5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process" EXACT [GO:0034428] synonym: "decreased nuclear 5'-3' exonucleolytic mRNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nuclear 5'-3' exonucleolytic mRNA catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'" EXACT [GO:0034428] synonym: "reduced nuclear 5'-3' exonucleolytic mRNA catabolic process" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T10:39:37Z [Term] id: FYPO:0003934 name: abolished nuclear mRNA catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process that degrades mRNA encoded in the nucleus does not occur. Total mRNA or a specific mRNA, such as the mRNA transcribed from a gene of interest, may be affected." [GO:0000956, PomBase:mah] synonym: "abolished nuclear mRNA breakdown" EXACT [GO:0000956] synonym: "abolished nuclear mRNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished nuclear mRNA catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "abolished nuclear mRNA catabolism" EXACT [GO:0000956] synonym: "abolished nuclear mRNA degradation" EXACT [GO:0000956] synonym: "abolished nuclear-transcribed mRNA catabolic process" EXACT [GO:0000956] synonym: "nuclear mRNA catabolic process abolished" EXACT [PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T10:42:42Z [Term] id: FYPO:0003935 name: decreased protein localization to Golgi apparatus, with protein mislocalized to endoplasmic reticulum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the endoplasmic reticulum instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to Golgi apparatus, with protein mislocalised to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to ER" EXACT [PomBase:mah] synonym: "reduced protein localization to Golgi apparatus, with protein mislocalized to endoplasmic reticulum" EXACT [PomBase:mah] is_a: FYPO:0004786 ! decreased protein localization to Golgi apparatus relationship: has_part FYPO:0003657 ! protein mislocalized to endoplasmic reticulum during vegetative growth created_by: midori creation_date: 2014-10-29T11:25:19Z [Term] id: FYPO:0003936 name: abnormal protein localization to Golgi apparatus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to Golgi apparatus" EXACT [PomBase:mah] synonym: "abnormal protein localization to Golgi apparatus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to Golgi apparatus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2014-10-29T11:26:09Z [Term] id: FYPO:0003937 name: increased cell population growth def: "A cell population phenotype in which cell population growth is increased relative to normal. Increased growth may reflect an increased growth rate (i.e. faster growth), growth that occurs to a greater extent than normal, or both. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide." [PomBase:mah] synonym: "fast aerobic cell population growth" NARROW [PomBase:mah] synonym: "increased aerobic cell population growth" NARROW [PomBase:mah] synonym: "increased growth" BROAD [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2014-10-29T11:58:04Z [Term] id: FYPO:0003938 name: increased cell population growth during glucose starvation def: "A cell growth phenotype in which cell population growth is increased relative to normal under conditions of glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "fast cell population growth during glucose starvation" NARROW [PomBase:mah] synonym: "increased cell population growth during glucose depletion" EXACT [PomBase:mah] synonym: "increased cell population growth during glucose deprivation" EXACT [PomBase:mah] synonym: "increased cell population growth during glucose limitation" RELATED [PomBase:mah] synonym: "increased cell population growth in response to glucose starvation" EXACT [PomBase:mah] synonym: "resistant to glucose starvation" RELATED [PomBase:mah] is_a: FYPO:0003937 ! increased cell population growth created_by: midori creation_date: 2014-10-29T11:58:39Z [Term] id: FYPO:0003939 name: abnormal m7G(5')pppN diphosphatase activity def: "A molecular function phenotype in which the observed rate of m7G(5')pppN diphosphatase activity is abnormal." [PomBase:mah] synonym: "abnormal mRNA decapping activity" RELATED [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-10-29T12:02:57Z [Term] id: FYPO:0003940 name: abolished m7G(5')pppN diphosphatase activity def: "A molecular function phenotype in which m7G(5')pppN diphosphatase activity is absent." [PomBase:mah] synonym: "abolished mRNA decapping activity" RELATED [PomBase:mah] synonym: "m7G(5')pppN diphosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003939 ! abnormal m7G(5')pppN diphosphatase activity created_by: midori creation_date: 2014-10-29T12:03:01Z [Term] id: FYPO:0003941 name: decreased m7G(5')pppN diphosphatase activity def: "A molecular function phenotype in which the observed rate of m7G(5')pppN diphosphatase activity is decreased." [PomBase:mah] synonym: "decreased mRNA decapping activity" RELATED [PomBase:mah] synonym: "reduced m7G(5')pppN diphosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003939 ! abnormal m7G(5')pppN diphosphatase activity created_by: midori creation_date: 2014-10-29T12:03:06Z [Term] id: FYPO:0003942 name: normal m7G(5')pppN diphosphatase activity def: "A molecular function phenotype in which the observed rate of m7G(5')pppN diphosphatase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mRNA decapping activity" RELATED [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-10-29T12:04:05Z [Term] id: FYPO:0003943 name: abnormal thioredoxin peroxidase activity def: "A molecular function phenotype in which the observed rate of thioredoxin peroxidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-10-29T12:12:01Z [Term] id: FYPO:0003944 name: increased thioredoxin peroxidase activity def: "A molecular function phenotype in which the observed rate of thioredoxin peroxidase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003943 ! abnormal thioredoxin peroxidase activity created_by: midori creation_date: 2014-10-29T12:12:07Z [Term] id: FYPO:0003945 name: increased RNA catabolic process during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process is increased during a cellular response to hydrogen peroxide." [PomBase:mah] synonym: "increased RNA breakdown during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA catabolic process during cellular response to H2O2" RELATED [PomBase:mah] synonym: "increased RNA catabolic process during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA catabolism during cellular response to hydrogen peroxide" EXACT [GO:0006401] synonym: "increased RNA degradation during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0002138 ! increased RNA catabolic process during vegetative growth created_by: midori creation_date: 2014-10-29T12:15:22Z [Term] id: FYPO:0003946 name: delayed onset of protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division begins later than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to cell division site" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein recruitment to cell division site" RELATED [PomBase:vw] synonym: "delayed protein localization to cell division site" EXACT [PomBase:mah] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2014-10-29T12:23:19Z [Term] id: FYPO:0003947 name: normal nonsense-mediated decay def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal NMD" EXACT [PomBase:mah] synonym: "normal nonsense-mediated decay during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nonsense-mediated decay during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" EXACT [GO:0000184] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T13:19:05Z [Term] id: FYPO:0003948 name: abnormal sulfite reductase activity def: "A molecular function phenotype in which the observed rate of sulfite reductase activity is abnormal." [PomBase:mah] synonym: "abnormal sulphite reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-10-29T13:29:08Z [Term] id: FYPO:0003949 name: decreased sulfite reductase activity def: "A molecular function phenotype in which the observed rate of sulfite reductase activity is decreased." [PomBase:mah] synonym: "decreased sulphite reductase activity" EXACT [PomBase:mah] synonym: "reduced sulfite reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003948 ! abnormal sulfite reductase activity created_by: midori creation_date: 2014-10-29T13:29:13Z [Term] id: FYPO:0003950 name: decreased protein localization to chromatin at replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is decreased." [PMID:12925774, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at replication origin" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at replication origins during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at replication origin" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-10-29T13:34:10Z [Term] id: FYPO:0003951 name: obsolete increased protein tyrosine phosphorylation during cellular response to heat def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to heat." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-tyrosine phosphorylation during cellular response to heat" EXACT [GO:0018108, PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "increased tyrosine phosphorylation during cellular response to heat" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0002129 created_by: midori creation_date: 2014-10-29T13:36:45Z [Term] id: FYPO:0003952 name: delayed onset of protein phosphorylation during cellular response to oxidative stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during a cellular response to oxidative stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein phosphorylation during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein phosphorylation during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein phosphorylation during oxidative stress response" EXACT [PomBase:vw] synonym: "delayed onset of protein/peptide phosphorylation during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "delayed protein phosphorylation during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0002830 ! delayed onset of protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-10-29T13:38:00Z [Term] id: FYPO:0003953 name: abnormal triglyceride biosynthetic process def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which triglyceride biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal TAG biosynthetic process" EXACT [PomBase:mah] synonym: "abnormal triacylglycerol biosynthesis" EXACT [GO:0019432] synonym: "abnormal triacylglycerol biosynthetic process" EXACT [PomBase:mah] synonym: "abnormal triglyceride biosynthesis" EXACT [PomBase:mah] synonym: "abnormal triglyceride biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal triglyceride biosynthetic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T13:51:09Z [Term] id: FYPO:0003954 name: decreased triglyceride biosynthetic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which triglyceride biosynthesis is decreased." [GO:0019493, PomBase:mah] synonym: "decreased TAG biosynthetic process" EXACT [PomBase:mah] synonym: "decreased triacylglycerol biosynthesis" EXACT [GO:0019432] synonym: "decreased triacylglycerol biosynthetic process" EXACT [PomBase:mah] synonym: "decreased triglyceride biosynthesis" EXACT [PomBase:mah] synonym: "decreased triglyceride biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased triglyceride biosynthetic process during vegetative growth" EXACT [PomBase:mah] synonym: "reduced triglyceride biosynthetic process" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T13:52:23Z [Term] id: FYPO:0003955 name: increased triglyceride biosynthetic process def: "A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which triglyceride biosynthesis is increased." [PomBase:mah] synonym: "increased TAG biosynthetic process" EXACT [PomBase:mah] synonym: "increased triacylglycerol biosynthesis" EXACT [GO:0019432] synonym: "increased triacylglycerol biosynthetic process" EXACT [PomBase:mah] synonym: "increased triglyceride biosynthesis" EXACT [GO:0019432] synonym: "increased triglyceride biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased triglyceride biosynthetic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-10-29T13:54:00Z [Term] id: FYPO:0003956 name: UAA suppression def: "A translation phenotype in which a tRNA pairs with mRNA at the stop codon UAA, and incorporates an amino acid residue into the nascent polypeptide." [PomBase:mah] synonym: "ochre suppression" EXACT [PomBase:mah] synonym: "ochre suppressor" EXACT [PomBase:mah] synonym: "UAA suppressor" EXACT [PomBase:mah] is_a: FYPO:0001797 ! abnormal translation created_by: midori creation_date: 2014-10-29T14:18:36Z [Term] id: FYPO:0003957 name: abolished tRNA guanosine N2,N2-dimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of two methyl groups to the N2 position of a guanine residue in a tRNA molecule is abolished. Normally, two methyl groups are transferred to the G26 residue." [PMID:10611485, PomBase:mah] synonym: "abolished tRNA dimethylation at N2 on G26" NARROW [PomBase:mah] synonym: "abolished tRNA guanosine N2,N2-dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA guanosine N2,N2-dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished tRNA m2,2G formation" EXACT [http://modomics.genesilico.pl/modifications/m2%2C2G/] synonym: "abolished tRNA N2,N2-dimethylguanosine formation" EXACT [PomBase:mah] synonym: "abolished tRNA N2-guanine dimethylation" EXACT [PMID:10611485, PomBase:mah] synonym: "abolished tRNA N2-guanine methylation" RELATED [PomBase:mah] synonym: "tRNA guanosine N2,N2-dimethylation abolished" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation is_a: FYPO:0008344 ! abolished tRNA modification created_by: midori creation_date: 2014-10-29T14:49:53Z [Term] id: FYPO:0003958 name: abnormal diacylglycerol O-acyltransferase activity def: "A molecular function phenotype in which the observed rate of diacylglycerol O-acyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal DGAT activity" EXACT [PMID:12963726] synonym: "abnormal diacylglycerol acyltransferase activity" BROAD [PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-04T11:16:20Z [Term] id: FYPO:0003959 name: decreased diacylglycerol O-acyltransferase activity def: "A molecular function phenotype in which the observed rate of diacylglycerol O-acyltransferase activity is decreased." [PomBase:mah] synonym: "decreased DGAT activity" EXACT [PMID:12963726] synonym: "decreased diacylglycerol acyltransferase activity" BROAD [PomBase:al] synonym: "reduced diacylglycerol O-acyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003958 ! abnormal diacylglycerol O-acyltransferase activity created_by: midori creation_date: 2014-11-04T11:16:25Z [Term] id: FYPO:0003960 name: increased diacylglycerol O-acyltransferase activity def: "A molecular function phenotype in which the observed rate of diacylglycerol O-acyltransferase activity is increased." [PomBase:mah] synonym: "increased DGAT activity" EXACT [PMID:12963726] synonym: "increased diacylglycerol acyltransferase activity" BROAD [PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003958 ! abnormal diacylglycerol O-acyltransferase activity created_by: midori creation_date: 2014-11-04T11:16:39Z [Term] id: FYPO:0003961 name: abnormal phospholipid:diacylglycerol acyltransferase activity def: "A molecular function phenotype in which the observed rate of phospholipid:diacylglycerol acyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal PDAT activity" EXACT [PMID:12963726] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-04T11:25:15Z [Term] id: FYPO:0003962 name: decreased phospholipid:diacylglycerol acyltransferase activity def: "A molecular function phenotype in which the observed rate of phospholipid:diacylglycerol acyltransferase activity is decreased." [PomBase:mah] synonym: "decreased PDAT activity" EXACT [PMID:12963726] synonym: "reduced phospholipid:diacylglycerol acyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003961 ! abnormal phospholipid:diacylglycerol acyltransferase activity created_by: midori creation_date: 2014-11-04T11:25:26Z [Term] id: FYPO:0003963 name: abnormal glutathione disulfide oxidoreductase activity def: "A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-04T11:33:14Z [Term] id: FYPO:0003964 name: decreased glutathione disulfide oxidoreductase activity def: "A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is decreased." [PomBase:mah] synonym: "reduced glutathione disulfide oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003963 ! abnormal glutathione disulfide oxidoreductase activity created_by: midori creation_date: 2014-11-04T11:33:20Z [Term] id: FYPO:0003965 name: increased glutathione disulfide oxidoreductase activity def: "A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003963 ! abnormal glutathione disulfide oxidoreductase activity created_by: midori creation_date: 2014-11-04T11:33:24Z [Term] id: FYPO:0003966 name: increased protein level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2014-11-04T11:35:36Z [Term] id: FYPO:0003967 name: decreased protein level in stationary phase def: "A cell phenotype in which the amount of protein measured in a cell is lover than normal when the population in which the cell is found is in stationary phase. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation in stationary phase" RELATED [PomBase:mah] synonym: "reduced protein level in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2014-11-04T11:37:03Z [Term] id: FYPO:0003968 name: inviable after spore germination, without cell division, with swollen elongated germ tube and bidirectional cell growth from spore body def: "A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal, then initiates growth from the opposite end of the spore body, and does not go on to form a viable dividing cell. The cell may undergo one or two rounds of nuclear division, but does not undergo cytokinesis." [PMID:9105045, PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, without cell division, with swollen elongated cell and bidirectional cell growth from spore body" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with swollen elongated germ tube and bidirectional cell growth from spore body" EXACT [PomBase:mah] is_a: FYPO:0002911 ! inviable after spore germination, without cell division, with swollen elongated germ tube created_by: midori creation_date: 2014-11-04T11:48:40Z [Term] id: FYPO:0003969 name: mislocalized mitotic spindle def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a mitotic spindle in an abnormal location. The normal location is centered at the midpoint of, and parallel to, the long axis of the cell." [PomBase:mah] synonym: "mislocalised mitotic spindle" EXACT [PomBase:mah] synonym: "mislocalized mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized spindle during mitosis" EXACT [PomBase:mah] synonym: "mislocalized spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2014-11-04T11:54:49Z [Term] id: FYPO:0003970 name: incomplete mitotic sister chromatid segregation, with chromatin bridge def: "A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and partially separated DNA masses are connected by one or more bridges formed of chromatin." [PMID:12455694, PomBase:mah] synonym: "incomplete mitotic sister chromatid segregation, with chromatin bridge, during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete mitotic sister chromatid separation, with chromatin bridge" RELATED [PomBase:mah] synonym: "incomplete sister chromatid segregation, with chromatin bridge during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003757 ! incomplete mitotic sister chromatid segregation created_by: midori creation_date: 2014-11-04T11:57:19Z [Term] id: FYPO:0003971 name: inviable after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness def: "A phenotype in which a spore germinates to produce a cell of that undergoes two or more rounds of cell division in which cells do not completely separate upon cytokinesis, form septa that are thicker than normal, and then die." [PMID:9046095, PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and thick septa" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness" EXACT [PomBase:mah] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis is_a: FYPO:0001406 ! increased septum thickness is_a: FYPO:0006878 ! inviable after spore germination, multiple cell divisions, with abnormal septation relationship: has_part FYPO:0001406 ! increased septum thickness relationship: has_part FYPO:0001972 ! abnormal cell separation after cytokinesis resulting in septated cell created_by: midori creation_date: 2014-11-04T12:16:20Z [Term] id: FYPO:0003972 name: abnormal exit from mitosis def: "A cellular process phenotype in which exit from mitosis is abnormal." [PomBase:mah] synonym: "abnormal exit from mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal exit from mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic exit" EXACT [GO:0010458] is_a: FYPO:0000186 ! abnormal cell division during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2014-11-04T15:32:11Z [Term] id: FYPO:0003973 name: abnormal nuclear pore localization def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is abnormal, resulting in an abnormal spatial arrangement of nuclear pores within the nuclear envelope." [PomBase:mah] synonym: "abnormal NPC localization" EXACT [PomBase:mah] synonym: "abnormal nuclear pore complex localization" EXACT [PomBase:mah] synonym: "abnormal nuclear pore distribution" EXACT [GO:0051664] synonym: "abnormal nuclear pore localisation" EXACT [PomBase:mah] synonym: "abnormal nuclear pore localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear pore localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-11-04T15:34:07Z [Term] id: FYPO:0003974 name: nuclear pore aggregation in cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more clusters of nuclear pores, associated with membrane fragments derived from the nuclear envelope, are present in the cytoplasm." [PMID:7877997, PomBase:mah] synonym: "aggregated nuclear pores present in cytoplasm" EXACT [PomBase:mah] synonym: "NPC aggregation in cytoplasm" EXACT [PomBase:mah] synonym: "nuclear pore aggregation in cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear pore aggregation in cytoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear pore complex aggregation in cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0003973 ! abnormal nuclear pore localization created_by: midori creation_date: 2014-11-04T15:39:11Z [Term] id: FYPO:0003975 name: fragmented nuclear envelope def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope is broken into multiple small fragments, none of which completely surrounds the contents of the nucleus." [PMID:7877997, PomBase:mah] synonym: "disrupted nuclear envelope" RELATED [PomBase:mah] synonym: "disrupted nuclear membrane" RELATED [PomBase:mah] synonym: "fragmented nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fragmented nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "fragmented nuclear membrane" RELATED [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth is_a: FYPO:0001919 ! fragmented nucleus during vegetative growth created_by: midori creation_date: 2014-11-04T15:44:30Z [Term] id: FYPO:0003976 name: inviable vegetative cell with fragmented nuclear envelope during mitotic telophase def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and has a nuclear envelope that is broken into multiple small fragments during mitotic telophase." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "inviable cell with fragmented nuclear envelope during mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with fragmented nuclear envelope during telophase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; vegetative cell with fragmented nuclear envelope during mitotic telophase" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell is_a: FYPO:0003975 ! fragmented nuclear envelope relationship: has_part FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0003975 ! fragmented nuclear envelope created_by: midori creation_date: 2014-11-04T15:54:07Z [Term] id: FYPO:0003977 name: inviable vegetative cell with nuclear pore aggregation in cytoplasm during mitotic telophase def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and one or more clusters of nuclear pores are present in the cytoplasm during mitotic telophase." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "inviable cell with nuclear pore aggregation in cytoplasm during mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with aggregated nuclear pores in cytoplasm during mitotic telophase" RELATED [PomBase:mah] synonym: "inviable vegetative cell with NPC aggregation in cytoplasm during mitotic telophase" EXACT [PomBase:mah] synonym: "inviable vegetative cell with nuclear pore aggregation in cytoplasm during telophase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable vegetative cell with nuclear pore complex aggregation in cytoplasm during mitotic telophase" EXACT [PomBase:mah] synonym: "lethal; vegetative cell with nuclear pore aggregation in cytoplasm during mitotic telophase" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell is_a: FYPO:0003973 ! abnormal nuclear pore localization relationship: has_part FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0003974 ! nuclear pore aggregation in cytoplasm created_by: midori creation_date: 2014-11-04T15:56:47Z [Term] id: FYPO:0003978 name: inviable vegetative cell with fragmented nuclear envelope and nuclear pore aggregation in cytoplasm during mitotic telophase def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and has a nuclear envelope that is broken into multiple small fragments and one or more clusters of nuclear pores present in the cytoplasm during mitotic telophase." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "inviable cell with fragmented nuclear envelope and nuclear pore aggregation in cytoplasm during mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with fragmented nuclear envelope and NPC aggregation in cytoplasm during mitotic telophase" EXACT [PomBase:mah] synonym: "inviable vegetative cell with fragmented nuclear envelope and nuclear pore aggregation in cytoplasm during telophase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable vegetative cell with fragmented nuclear envelope and nuclear pore complex aggregation in cytoplasm during mitotic telophase" EXACT [PomBase:mah] synonym: "lethal; vegetative cell with fragmented nuclear envelope and nuclear pore aggregation in cytoplasm during mitotic telophase" EXACT [PomBase:mah] is_a: FYPO:0003973 ! abnormal nuclear pore localization is_a: FYPO:0003976 ! inviable vegetative cell with fragmented nuclear envelope during mitotic telophase relationship: has_part FYPO:0003974 ! nuclear pore aggregation in cytoplasm created_by: midori creation_date: 2014-11-04T15:58:32Z [Term] id: FYPO:0003979 name: abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell with 1C DNA content per nucleus def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have condensed chromosomes, a single, normally located septum, and 1C DNA content in each nucleus, under conditions where arrest does not normally occur." [PMID:8313905, PomBase:mah, PomBase:vw] comment: This phenotype arises when a cell fails to exit mitosis correctly, such that chromosomes remain condensed and cytokinesis is not completed. In wild-type cells, chromosomes are condensed only in M phase. This term can be used for mutants in which chromosomes are condensed but other normal features of M phase cells are not observed. synonym: "abnormal cell cycle arrest with condensed chromosomes, septated cell with 1C DNA content per nucleus during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell with 1C DNA content per nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell with 1C nuclei" EXACT [PomBase:mah] is_a: FYPO:0004719 ! abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell relationship: output_of FYPO:0003972 ! abnormal exit from mitosis created_by: midori creation_date: 2014-11-04T16:04:34Z [Term] id: FYPO:0003980 name: abnormal glutathione transferase activity def: "A molecular function phenotype in which the observed rate of glutathione transferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-04T16:13:56Z [Term] id: FYPO:0003981 name: increased glutathione transferase activity def: "A molecular function phenotype in which the observed rate of glutathione transferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003980 ! abnormal glutathione transferase activity created_by: midori creation_date: 2014-11-04T16:14:03Z [Term] id: FYPO:0003982 name: abnormal disulfide oxidoreductase activity def: "A molecular function phenotype in which the observed rate of disulfide oxidoreductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-04T16:15:59Z [Term] id: FYPO:0003983 name: increased disulfide oxidoreductase activity def: "A molecular function phenotype in which the observed rate of disulfide oxidoreductase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003982 ! abnormal disulfide oxidoreductase activity created_by: midori creation_date: 2014-11-04T16:16:04Z [Term] id: FYPO:0003984 name: altered cellular amino acid level during vegetative growth def: "A cell phenotype in which the amount of an amino acid measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "abnormal cellular amino acid level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular amino acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered level of amino acid in cell" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2014-11-04T16:21:46Z [Term] id: FYPO:0003985 name: decreased cellular amino acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of an amino acid measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular amino acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular amino acid level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of amino acid in cell" EXACT [PomBase:mah] synonym: "reduced cellular amino acid level" EXACT [PomBase:mah] synonym: "reduced level of amino acid in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0003984 ! altered cellular amino acid level during vegetative growth created_by: midori creation_date: 2014-11-04T16:23:35Z [Term] id: FYPO:0003986 name: increased cellular amino acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of an amino acid measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular amino acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular amino acid level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0003984 ! altered cellular amino acid level during vegetative growth created_by: midori creation_date: 2014-11-04T16:24:49Z [Term] id: FYPO:0003987 name: abnormal actin cortical patch def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of actin cortical patches is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cortical patches" EXACT [PomBase:mah] synonym: "abnormal actin patch" EXACT [PomBase:mah] synonym: "abnormal F-actin patch" EXACT [PomBase:mah] is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth relationship: output_of FYPO:0000790 ! abnormal actin cortical patch organization created_by: midori creation_date: 2014-11-05T10:41:05Z [Term] id: FYPO:0003988 name: mislocalized actin cortical patches during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has actin cortical patches in one or more abnormal locations." [PomBase:mah] synonym: "abnormal actin cortical patch location during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch position during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalised actin cortical patches during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized actin cortical patches during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized actin patches during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized F-actin patches during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0006771 ! mislocalized actin cortical patches relationship: output_of FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth created_by: midori creation_date: 2014-11-05T10:53:55Z [Term] id: FYPO:0003989 name: inviable stubby mononucleate vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable and has one nucleus, and the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable stubby mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable stubby mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable watermelon-shaped mononucleate vegetative cell" EXACT [PomBase:mah] synonym: "lethal; stubby mononucleate vegetative cell" EXACT [PomBase:mah] synonym: "stubby mononucleate inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002107 ! inviable stubby vegetative cell is_a: FYPO:0002731 ! mononucleate relationship: has_part FYPO:0002731 ! mononucleate created_by: midori creation_date: 2014-11-05T11:44:54Z [Term] id: FYPO:0003990 name: sensitive to DNA damage during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to DNA damage during S phase of the mitotic cell cycle." [PMID:15643072, PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to DNA damage in culture. If you have assayed the response to DNA damage at the subcellular or molecular level, consider annotating to 'abnormal cellular response to DNA damage stimulus' (FYPO:0000157). Also consider specific phenotype terms for sensitivity to substances or other stimuli that can damage DNA, e.g. 'sensitive to DNA damaging agents' (FYPO:0000266), 'sensitive to methyl methanesulfonate' (FYPO:0000089), 'sensitive to UV' (FYPO:0000268), etc. synonym: "decreased growth during cellular response to DNA damage during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to DNA damage during mitotic S phase" EXACT [PomBase:mah] synonym: "hypersensitive to DNA damage during mitotic S phase" EXACT [PomBase:mah] synonym: "sensitive to DNA damage during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DNA damage during S phase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000265 ! sensitive to DNA damage created_by: midori creation_date: 2014-11-05T14:33:34Z [Term] id: FYPO:0003991 name: increased RNA level in stationary phase def: "A cell phenotype in which the amount of RNA measured in a cell is higher than normal when the population in which the cell is found is in stationary phase. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation in stationary phase" RELATED [PomBase:mah] synonym: "increased transcript level in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2014-11-05T15:01:20Z [Term] id: FYPO:0003992 name: normal RNA level during cellular response to menadione def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to menadione is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to menadione" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to menadione" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to menadione" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2014-11-05T15:02:45Z [Term] id: FYPO:0003993 name: decreased RNA level during cellular response to menadione def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to menadione is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to menadione" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to menadione" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to menadione" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-11-05T15:33:14Z [Term] id: FYPO:0003994 name: normal succinate dehydrogenase activity def: "A molecular function phenotype in which the observed rate of succinate dehydrogenase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-11-05T15:36:33Z [Term] id: FYPO:0003995 name: abnormal DNA primase activity def: "A molecular function phenotype in which the observed rate of DNA primase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-12T13:06:54Z [Term] id: FYPO:0003996 name: abolished DNA primase activity def: "A molecular function phenotype in which DNA primase activity is absent." [PomBase:mah] synonym: "DNA primase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003995 ! abnormal DNA primase activity created_by: midori creation_date: 2014-11-12T13:07:02Z [Term] id: FYPO:0003997 name: decreased DNA primase activity def: "A molecular function phenotype in which the observed rate of DNA primase activity is decreased." [PomBase:mah] synonym: "reduced DNA primase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003995 ! abnormal DNA primase activity created_by: midori creation_date: 2014-11-12T13:07:12Z [Term] id: FYPO:0003998 name: increased DNA primase activity def: "A molecular function phenotype in which the observed rate of DNA primase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0003995 ! abnormal DNA primase activity created_by: midori creation_date: 2014-11-12T13:07:16Z [Term] id: FYPO:0003999 name: increased glutathione synthase activity def: "A molecular function phenotype in which the observed rate of glutathione synthase activity is increased." [PomBase:mah] synonym: "increased glutathione synthetase activity" EXACT [GO:0004363] synonym: "increased GSH synthase activity" EXACT [GO:0004363] synonym: "increased phosphoribosylformylglycinamidine cyclo-ligase activity" EXACT [GO:0004363] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002856 ! abnormal glutathione synthase activity created_by: midori creation_date: 2014-11-12T13:19:40Z [Term] id: FYPO:0004000 name: increased glutamate-cysteine ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-cysteine ligase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0002853 ! abnormal glutamate-cysteine ligase activity created_by: midori creation_date: 2014-11-12T13:22:27Z [Term] id: FYPO:0004001 name: normal cellular glutathione level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular glutathione level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular glutathione level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular GSH level" EXACT [CHEBI:16856, PomBase:al] synonym: "normal cellular L-gamma-glutamyl-L-cysteinylglycine level" EXACT [CHEBI:16856] synonym: "normal cellular reduced glutathione level" EXACT [CHEBI:16856, PomBase:al] synonym: "normal glutathione accumulation" RELATED [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2014-11-12T13:23:46Z [Term] id: FYPO:0004002 name: increased duration of protein phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to hydroxyurea. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "increased duration of protein phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein phosphorylation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000548 ! increased duration of protein modification during vegetative growth created_by: midori creation_date: 2014-11-12T13:32:38Z [Term] id: FYPO:0004003 name: delayed onset of replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing begins later than normal. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted." [GO:0031297, PomBase:mah] synonym: "delayed onset of collapsed replication fork processing" EXACT [GO:0031297] synonym: "delayed onset of recovery from replication fork arrest" EXACT [GO:0031297] synonym: "delayed onset of recovery from replication fork stalling" EXACT [GO:0031297] synonym: "delayed onset of replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of replication fork restart" RELATED [GO:0031297] synonym: "delayed onset of replication restart" RELATED [GO:0031297] synonym: "delayed replication fork processing" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2014-11-12T13:37:22Z [Term] id: FYPO:0004004 name: normal pre-replicative complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pre-replicative complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal pre-RC assembly" EXACT [PomBase:mah] synonym: "normal pre-replicative complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal pre-replicative complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal pre-replicative complex formation" EXACT [GO:0006267, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-11-12T13:39:24Z [Term] id: FYPO:0004005 name: increased spatial extent of chromatin binding def: "A molecular function phenotype in which a gene product binds chromatin over a larger portion of the chromosome than normal." [PMID:18753627, PomBase:mah] is_a: FYPO:0002576 ! abnormal chromatin binding created_by: midori creation_date: 2014-11-12T13:40:59Z [Term] id: FYPO:0004006 name: normal protein level during cellular response to menadione def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to menadione is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to menadione" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to menadione during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2014-11-12T13:49:44Z [Term] id: FYPO:0004007 name: decreased protein level during cellular response to menadione def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to menadione is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to menadione" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to menadione" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-11-12T13:53:46Z [Term] id: FYPO:0004008 name: normal rRNA transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of ribosomal DNA into ribosomal RNA occurs to a normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal rDNA transcription" EXACT [PomBase:mah] synonym: "normal ribosomal RNA transcription" EXACT [PomBase:mah] synonym: "normal rRNA transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rRNA transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2014-11-12T14:04:59Z [Term] id: FYPO:0004009 name: decreased rRNA transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of ribosomal DNA into ribosomal RNA occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased rDNA transcription" EXACT [PomBase:mah] synonym: "decreased ribosomal RNA transcription" EXACT [PomBase:mah] synonym: "decreased rRNA transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rRNA transcription during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rRNA transcription" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2014-11-12T14:08:28Z [Term] id: FYPO:0004010 name: decreased translation of ribosomal proteins during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more ribosomal proteins is decreased." [PMID:2839305, PomBase:mah] comment: Consider annotating to 'decreased ribosomal protein level' (FYPO:0006944). synonym: "decreased translation of ribosomal proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced translation of ribosomal proteins during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001798 ! decreased translation created_by: midori creation_date: 2014-11-12T14:10:21Z [Term] id: FYPO:0004011 name: increased degradation of ribosomal proteins during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of degradation of one or more ribosomal proteins is increased." [PMID:2839305, PomBase:mah] comment: Consider annotating to 'decreased ribosomal protein level' (FYPO:0006944). synonym: "increased degradation of ribosomal proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased ribosomal protein breakdown during vegetative growth" EXACT [GO:0030163] synonym: "increased ribosomal protein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "increased ribosomal protein catabolism during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "increased ribosomal protein degradation cycle during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000847 ! increased protein degradation during vegetative growth created_by: midori creation_date: 2014-11-12T14:11:25Z [Term] id: FYPO:0004012 name: normal cell surface pyruvylated galactose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4,6-pyruvylated D-galactose (4,6-O-[(1R)-1-carboxyethylidene]-D-galactose) measured at the cell surface is normal (i.e. indistinguishable from wild type). The cell surface refers to the external part of the cell wall and/or plasma membrane." [PMID:25195688, PomBase:mah] synonym: "normal cell surface 4,6-4,6-O-[(1R)-1-carboxyethylidene]-D-galactose level" EXACT [CHEBI:61747] synonym: "normal cell surface 4,6-pyruvylated D-galactose level" EXACT [CHEBI:61747, PomBase:mah] synonym: "normal cell surface PvGal level" EXACT [PMID:25195688] synonym: "normal cell surface pyruvylated galactose level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell surface pyruvylated galactose level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of pyruvylated galactose at cell surface" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2014-11-13T15:00:50Z [Term] id: FYPO:0004013 name: decreased cell surface pyruvylated galactose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4,6-pyruvylated D-galactose (4,6-O-[(1R)-1-carboxyethylidene]-D-galactose) measured at the cell surface is lower than normal. The cell surface refers to the external part of the cell wall and/or plasma membrane." [PMID:25195688, PomBase:mah] synonym: "decreased cell surface 4,6-4,6-O-[(1R)-1-carboxyethylidene]-D-galactose level" EXACT [CHEBI:61747] synonym: "decreased cell surface 4,6-pyruvylated D-galactose level" EXACT [CHEBI:61747, PomBase:mah] synonym: "decreased cell surface PvGal level" EXACT [PMID:25195688] synonym: "decreased cell surface pyruvylated galactose level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell surface pyruvylated galactose level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of pyruvylated galactose at cell surface" EXACT [PomBase:mah] synonym: "reduced cell surface pyruvylated galactose level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-11-13T15:06:16Z [Term] id: FYPO:0004014 name: normal mitotic cell cycle regulation during cellular response to UV def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to UV." [PMID:7957098, PomBase:mah] synonym: "normal cell cycle regulation during cellular response to UV" EXACT [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to UV during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle delay following UV exposure" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation in response to UV" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2014-11-19T11:29:45Z [Term] id: FYPO:0004015 name: mitochondria present in normal numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a normal number of mitochondria." [PMID:2065367, PomBase:mah] synonym: "mitochondria present in normal numbers during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitochondria present in normal numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006034 ! normal mitochondrion created_by: midori creation_date: 2014-11-19T14:35:46Z [Term] id: FYPO:0004016 name: normal cellular mtDNA level def: "A cell phenotype in which the amount of mitochondrial DNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PMID:2065367, PomBase:mah] synonym: "normal mitochondrial DNA content" EXACT [PomBase:mah] synonym: "normal mitochondrial DNA level" EXACT [PomBase:mah] synonym: "normal mtDNA level" EXACT [PomBase:mah] synonym: "normal mtDNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mtDNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001383 ! normal DNA content created_by: midori creation_date: 2014-11-19T14:38:42Z [Term] id: FYPO:0004017 name: normal cytochrome-c oxidase activity def: "A molecular function phenotype in which the observed rate of cytochrome-c oxidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'normal cellular respiration' (FYPO:0000566). is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-11-19T14:41:26Z [Term] id: FYPO:0004018 name: normal mitochondrial electron transport, NADH to ubiquinone def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from NADH to ubiquinone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitochondrial electron transport, NADH to ubiquinone, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial electron transport, NADH to ubiquinone, during vegetative growth" EXACT [PomBase:mah] synonym: "normal NADH cytochrome c oxidoreductase" RELATED [PMID:2065367] synonym: "normal NADH dehydrogenase (quinone) activity and ubiquinol-cytochrome-c reductase activity" RELATED [PMID:2065367, PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-11-19T14:42:56Z [Term] id: FYPO:0004019 name: normal mitochondrial electron transport, succinate to ubiquinone def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from succinate to ubiquinone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitochondrial electron transport, succinate to ubiquinone, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial electron transport, succinate to ubiquinone, during vegetative growth" EXACT [PomBase:mah] synonym: "normal succinate cytochrome c oxidoreductase" RELATED [PMID:2065367] synonym: "normal succinate dehydrogenase (ubiquinone) activity and ubiquinol-cytochrome-c reductase activity" RELATED [PMID:2065367, PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2014-11-19T14:44:36Z [Term] id: FYPO:0004020 name: decreased mitochondrial electron transport, succinate to ubiquinone def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from succinate to ubiquinone is decreased." [GO:0006121, PomBase:mah] synonym: "decreased mitochondrial electron transport, succinate to ubiquinone, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial electron transport, succinate to ubiquinone, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased succinate cytochrome c oxidoreductase" RELATED [PMID:2065367] synonym: "decreased succinate dehydrogenase (ubiquinone) activity and ubiquinol-cytochrome-c reductase activity" RELATED [PMID:2065367, PomBase:vw] synonym: "reduced mitochondrial electron transport, succinate to ubiquinone" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-11-19T14:45:44Z [Term] id: FYPO:0004021 name: long polar microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form polar microtubules that are longer than normal. Polar microtubules are the spindle microtubules that come from each pole and overlap at the spindle midzone." [GO:0005827, PomBase:mah] synonym: "elongated polar microtubules" EXACT [PomBase:mah] synonym: "long polar microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long polar microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000055 ! long microtubules created_by: midori creation_date: 2014-11-19T15:05:50Z [Term] id: FYPO:0004022 name: abnormal cell cycle arrest in mitotic metaphase with long polar microtubules def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase under conditions where arrest does not normally occur, with polar microtubules that are longer than normal." [PMID:16079915, PomBase:mah] synonym: "abnormal cell cycle arrest in metaphase with long polar microtubules during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic metaphase with condensed chromosomes and long polar microtubules" EXACT [Pombase:vw] synonym: "abnormal cell cycle arrest in mitotic metaphase with elongated polar microtubules" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic metaphase with long polar microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in metaphase with long polar microtubules" EXACT [GO:0000089] synonym: "abolished mitotic metaphase/anaphase transition with long polar microtubules" RELATED [PomBase:mah] is_a: FYPO:0000620 ! abnormal cell cycle arrest in mitotic metaphase is_a: FYPO:0004021 ! long polar microtubules relationship: has_part FYPO:0004021 ! long polar microtubules created_by: midori creation_date: 2014-11-19T15:08:19Z [Term] id: FYPO:0004023 name: increased duration of protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle for a longer time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "increased duration of protein localization to mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to spindle during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein localization to mitotic spindle" EXACT [PomBase:vw] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2014-11-19T15:12:15Z [Term] id: FYPO:0004024 name: normal protein localization to cytoplasmic stress granule def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to cytoplasmic stress granules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoplasmic stress granule" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic stress granule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cytoplasmic stress granule during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to stress granule" EXACT [GO:0010494] is_a: FYPO:0001788 ! normal protein localization to cytoplasm created_by: midori creation_date: 2014-11-19T15:13:47Z [Term] id: FYPO:0004025 name: resistance to carbendazim def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of the tubulin poison carbendazim (mecarzole; MBC) than normal." [PomBase:mah] synonym: "resistance to carbendazim during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to carbendazim during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to MBC" EXACT [CHEBI:3392] synonym: "resistance to methyl benzimidazole-2-yl-carbamate" EXACT [CHEBI:3392] synonym: "resistance to methylbenzylcarbamylate" EXACT [PMID:8247131] synonym: "resistant to carbendazim" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-11-19T15:41:42Z [Term] id: FYPO:0004026 name: loss of template switch-mediated chromosomal rearrangement during replication fork processing def: "A cell phenotype in which the increase in gross chromosomal rearrangements that normally results from synthesis template switching during processing of arrested replication forks is diminished or abolished." [PMID:25313826, PomBase:mah] is_a: FYPO:0003587 ! loss of gross chromosomal rearrangement during replication fork processing created_by: midori creation_date: 2014-11-19T15:43:04Z [Term] id: FYPO:0004027 name: normal 5' deoxyribonuclease (pyrimidine dimer) activity def: "A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-11-19T17:24:06Z [Term] id: FYPO:0004028 name: abnormal 5' deoxyribonuclease (pyrimidine dimer) activity def: "A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-19T17:25:49Z [Term] id: FYPO:0004029 name: abolished 5' deoxyribonuclease (pyrimidine dimer) activity def: "A molecular function phenotype in which 5' deoxyribonuclease (pyrimidine dimer) activity is absent." [PomBase:mah] synonym: "5' deoxyribonuclease (pyrimidine dimer) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004028 ! abnormal 5' deoxyribonuclease (pyrimidine dimer) activity created_by: midori creation_date: 2014-11-19T17:25:54Z [Term] id: FYPO:0004030 name: decreased 5' deoxyribonuclease (pyrimidine dimer) activity def: "A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is decreased." [PomBase:mah] synonym: "reduced 5' deoxyribonuclease (pyrimidine dimer) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004028 ! abnormal 5' deoxyribonuclease (pyrimidine dimer) activity created_by: midori creation_date: 2014-11-19T17:26:08Z [Term] id: FYPO:0004031 name: decreased UV-damage excision repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair occurs to a lower extent than normal. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [GO:0070914, PomBase:mah] synonym: "decreased cyclobutane pyrimidine dimer repair" NARROW [GO:0070914] synonym: "decreased pyrimidine-pyrimidone 6-4 photoproduct repair" NARROW [GO:0070914] synonym: "decreased UV-damage excision repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased UV-damage excision repair during vegetative growth" EXACT [PomBase:mah] synonym: "reduced removal of 6-4 photoproducts" NARROW [GO:0070914, PomBase:vw] synonym: "reduced removal of cyclobutane pyrimidine dimers" NARROW [GO:0070914, PomBase:vw] synonym: "reduced UV-damage excision repair" EXACT [PomBase:mah] is_a: FYPO:0000188 ! abnormal DNA repair during vegetative growth created_by: midori creation_date: 2014-11-19T17:29:31Z [Term] id: FYPO:0004032 name: increased protein localization to chromatin at rDNA def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal DNA repeat regions is increased." [PMID:25392932, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at rDNA" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at ribosomal DNA" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at rRNA genes" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-11-25T10:59:45Z [Term] id: FYPO:0004033 name: increased protein localization to chromatin at tRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at tRNA genes is increased." [PMID:25392932, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at tRNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at transfer RNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at tRNA genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-11-25T11:03:58Z [Term] id: FYPO:0004034 name: decreased glutathione transferase activity def: "A molecular function phenotype in which the observed rate of glutathione transferase activity is decreased." [PomBase:mah] synonym: "reduced glutathione transferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003980 ! abnormal glutathione transferase activity created_by: midori creation_date: 2014-11-25T11:13:07Z [Term] id: FYPO:0004035 name: abnormal thioredoxin-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of thioredoxin-disulfide reductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-25T11:14:45Z [Term] id: FYPO:0004036 name: increased thioredoxin-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of thioredoxin-disulfide reductase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004035 ! abnormal thioredoxin-disulfide reductase activity created_by: midori creation_date: 2014-11-25T11:14:50Z [Term] id: FYPO:0004037 name: decreased protein level during cellular response to mercury ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to mercury ions is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to mercury ion" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to mercury" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to mercury ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to mercury ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to mercury ion" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-11-25T11:17:44Z [Term] id: FYPO:0004038 name: delayed onset of increase in RNA level during cellular response to hydrogen peroxide def: "A cell phenotype in which an increase in RNA level that occurs as part of a cellular response to hydrogen peroxide begins later than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:9450957, PomBase:mah] synonym: "delayed increase in RNA level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "delayed onset of increase in RNA level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "delayed onset of increase in RNA level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of increase in RNA level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of increase in transcript level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0000194 ! abnormal cellular response to hydrogen peroxide is_a: FYPO:0007793 ! delayed onset of increase in RNA level during cellular response to oxidative stress created_by: midori creation_date: 2014-12-16T14:47:06Z [Term] id: FYPO:0004039 name: abolished primary amine oxidase activity def: "A molecular function phenotype in which primary amine oxidase activity is absent." [PomBase:mah] synonym: "primary amine oxidase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003072 ! abnormal primary amine oxidase activity created_by: midori creation_date: 2014-11-25T11:22:59Z [Term] id: FYPO:0004040 name: mitotic cell cycle arrest phenotype def: "A cell cycle phenotype that affects or involves the normal or abnormal occurrence of mitotic cell cycle arrest. In mitotic cell cycle arrest, progression through the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, or M)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell cycle arrest phenotype during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle arrest phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast mitotic cell cycle arrest phenotype" EXACT [PomBase:mah] is_a: FYPO:0001024 ! cell cycle arrest phenotype created_by: midori creation_date: 2014-11-27T12:18:23Z [Term] id: FYPO:0004041 name: normal primary amine oxidase activity def: "A molecular function phenotype in which the observed rate of a primary amine oxidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-11-25T11:23:49Z [Term] id: FYPO:0004042 name: fragmented septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms pieces of a septum rather than a septum that completely bisects the cell." [PMID:21931816, PomBase:mah] synonym: "fragmented septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fragmented septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005870 ! incomplete septum created_by: midori creation_date: 2014-11-25T11:51:06Z [Term] id: FYPO:0004043 name: tetranucleate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains four nuclei." [PomBase:mah] synonym: "tetranucleate cells during vegetative growth" EXACT [PomBase:al] synonym: "tetranucleate during vegetative growth" EXACT [PomBase:mah] synonym: "tetranucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell created_by: midori creation_date: 2014-11-25T11:58:10Z [Term] id: FYPO:0004044 name: elongated tetranucleate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains four nuclei and is elongated." [PomBase:mah] synonym: "elongated tetranucleate cells during vegetative growth" EXACT [PomBase:al] synonym: "elongated tetranucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long tetranucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0003342 ! elongated multinucleate cell created_by: midori creation_date: 2014-11-25T11:59:21Z [Term] id: FYPO:0004045 name: elongated tetranucleate vegetative cell with fragmented septum def: "A cell morphology phenotype in which vegetative a cell is elongated, and contains four nuclei and pieces of a septum that does not completely bisect the cell." [PMID:21931816, PomBase:mah] synonym: "elongated tetranucleate cells with fragmented septum during vegetative growth" EXACT [PomBase:al] synonym: "elongated tetranucleate vegetative cell with fragmented septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long tetranucleate vegetative cell with fragmented septum" EXACT [PomBase:mah] is_a: FYPO:0004044 ! elongated tetranucleate vegetative cell is_a: FYPO:0004046 ! tetranucleate vegetative cell with fragmented septum created_by: midori creation_date: 2014-11-25T12:00:56Z [Term] id: FYPO:0004046 name: tetranucleate vegetative cell with fragmented septum def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains four nuclei and pieces of a septum that does not completely bisect the cell." [PMID:21931816, PomBase:mah] synonym: "tetranucleate cells with fragmented septum during vegetative growth" EXACT [PomBase:mah] synonym: "tetranucleate vegetative cell with fragmented septum during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0004042 ! fragmented septum created_by: midori creation_date: 2014-11-25T12:02:21Z [Term] id: FYPO:0004047 name: binucleate vegetative cell with fragmented septum def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains two nuclei and pieces of a septum that does not completely bisect the cell." [PMID:21931816, PomBase:mah] synonym: "binucleate cells with fragmented septum during vegetative growth" EXACT [PomBase:mah] synonym: "binucleate vegetative cell with fragmented septum during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001222 ! binucleate vegetative cell is_a: FYPO:0004042 ! fragmented septum created_by: midori creation_date: 2014-11-25T12:04:23Z [Term] id: FYPO:0004048 name: abnormal glutathione peroxidase activity def: "A molecular function phenotype in which the observed rate of glutathione peroxidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-11-25T12:11:36Z [Term] id: FYPO:0004049 name: increased glutathione peroxidase activity def: "A molecular function phenotype in which the observed rate of glutathione peroxidase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004048 ! abnormal glutathione peroxidase activity created_by: midori creation_date: 2014-11-25T12:11:42Z [Term] id: FYPO:0004050 name: decreased glutathione transferase activity during stationary phase def: "A molecular function phenotype in which the observed rate of glutathione transferase activity is decreased in a cell culture in stationary phase." [PomBase:mah] synonym: "decreased glutathione transferase activity in stationary phase" EXACT [PomBase:mah] synonym: "reduced glutathione transferase activity during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0004034 ! decreased glutathione transferase activity created_by: midori creation_date: 2014-11-25T12:49:00Z [Term] id: FYPO:0004051 name: increased glutathione transferase activity during stationary phase def: "A molecular function phenotype in which the observed rate of glutathione transferase activity is increased in a cell culture in stationary phase." [PomBase:mah] synonym: "increased glutathione transferase activity in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0003981 ! increased glutathione transferase activity created_by: midori creation_date: 2014-11-25T12:52:09Z [Term] id: FYPO:0004052 name: RNA absent from cell during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to hydrogen peroxide. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "RNA absent from cell during cellular response to H2O2" EXACT [PomBase:mah] synonym: "RNA absent from cell during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA absent from cell during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "transcripts absent from cell during cellular response to hydrogen peroxide" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001116 ! decreased RNA level during cellular response to hydrogen peroxide is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: midori creation_date: 2014-11-25T12:53:07Z [Term] id: FYPO:0004053 name: obsolete cut during cellular response to UV def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to ultraviolet light. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "cut during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation during cellular response to UV" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2014-11-25T14:23:33Z [Term] id: FYPO:0004054 name: abolished protein localization to nucleus during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during cellular response to salt stress" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during salt stress" EXACT [PomBase:al] synonym: "nuclear exclusion during cellular response to salt stress" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during cellular response to salt stress" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: midori creation_date: 2014-11-25T14:26:16Z [Term] id: FYPO:0004055 name: decreased protein localization to nucleus during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during salt stress" EXACT [PomBase:al] synonym: "reduced protein localization to nucleus during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth is_a: FYPO:0004455 ! decreased protein localization to nucleus created_by: midori creation_date: 2014-11-25T14:28:03Z [Term] id: FYPO:0004056 name: decreased protein localization to nucleus, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased, and some of the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus, with protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "decreased protein localization in nucleus, with protein mislocalized to cytoplasm" EXACT [GO:0034504] synonym: "decreased protein localization to nucleus, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2014-11-25T14:28:46Z [Term] id: FYPO:0004057 name: increased intragenic meiotic recombination def: "A cellular process phenotype in which the occurrence of intragenic meiotic recombination is increased. Intragenic meiotic recombination can result in gene conversion events." [PMID:19436749, PomBase:mah] synonym: "increased meiotic intragenic recombination" EXACT [PomBase:al] is_a: FYPO:0000487 ! increased meiotic recombination created_by: midori creation_date: 2014-11-25T14:36:39Z [Term] id: FYPO:0004058 name: decreased meiotic recombination at CRE promoter def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination at a CRE promoter in a chromosome is decreased." [PMID:19436749, PomBase:mah] synonym: "decreased meiotic recombination at M26 site" EXACT [PomBase:mah, SO:0001843] synonym: "reduced meiotic recombination at CRE promoter" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2014-11-25T14:39:56Z [Term] id: FYPO:0004059 name: normal meiotic recombination at CRE promoter def: "A cellular process phenotype in which reciprocal meiotic recombination is normal (i.e. indistinguishable from wild type) at an CRE promoter in a chromosome." [PomBase:mah] synonym: "normal meiotic recombination at M26 binding site" EXACT [SO:0001843] is_a: FYPO:0000488 ! normal meiotic recombination created_by: midori creation_date: 2014-11-25T14:41:47Z [Term] id: FYPO:0004060 name: abolished endocytosis during meiotic interphase II def: "A cellular process phenotype in which endocytosis does not occur during meiotic interphase II, i.e. the phase between the end of meiosis I cytokinesis the beginning of meiosis II prophase. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [GO:0044844, PomBase:mah] synonym: "abolished actin-mediated endocytosis during meiotic interphase II" EXACT [PomBase:vw] synonym: "abolished protein internalization during meiotic interphase II" NARROW [PomBase:vw] synonym: "absent endocytosis during meiotic interphase II" EXACT [PomBase:mah] synonym: "endocytosis abolished during meiotic interphase II" EXACT [PomBase:mah] is_a: FYPO:0003886 ! abnormal endocytosis created_by: midori creation_date: 2014-11-25T15:47:31Z [Term] id: FYPO:0004061 name: decreased UV-damage excision repair during mitotic G1 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair occurs to a lower extent than normal during G1 phase of the mitotic cell cycle. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [GO:0070914, PomBase:mah] synonym: "decreased UV-damage excision repair during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased UV-damage excision repair during mitotic G1 during vegetative growth" EXACT [PomBase:mah] synonym: "reduced UV-damage excision repair during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0004031 ! decreased UV-damage excision repair created_by: midori creation_date: 2014-11-25T16:13:13Z [Term] id: FYPO:0004062 name: increased duration of protein phosphorylation during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to salt stress. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein phosphorylation during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein phosphorylation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein phosphorylation during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2014-11-25T16:16:58Z [Term] id: FYPO:0004063 name: normal protein localization to cytoplasm during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the cytoplasm is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoplasm during cellular response to salt stress" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasm during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cytoplasm during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasm during salt stress" EXACT [PomBase:al] is_a: FYPO:0001788 ! normal protein localization to cytoplasm created_by: midori creation_date: 2014-11-25T16:18:38Z [Term] id: FYPO:0004064 name: abnormal transcription during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of RNA from one or more DNA templates is abnormal." [GO:0006351, PomBase:mah] synonym: "abnormal DNA-dependent transcription during vegetative growth" EXACT [GO:0006351] synonym: "abnormal transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal transcription, DNA-templated, during vegetative growth" EXACT [GO:0006351] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth is_a: FYPO:0005502 ! abnormal transcription created_by: midori creation_date: 2014-11-25T16:38:51Z [Term] id: FYPO:0004065 name: abnormal transcription elongation from RNA polymerase II promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the elongation of a transcript initiated from an RNA polymerase II promoter is abnormal." [GO:0006368, PomBase:mah] synonym: "abnormal RNA elongation from RNA polymerase II promoter" EXACT [GO:0006368] synonym: "abnormal transcription elongation from RNA polymerase II promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal transcription elongation from RNA polymerase II promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2014-11-25T16:41:18Z [Term] id: FYPO:0004066 name: increased protein localization to chromatin at protein coding gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more protein-coding genes is increased." [PMID:19328067, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at protein coding gene" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at protein-coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-11-25T16:43:55Z [Term] id: FYPO:0004067 name: decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal." [GO:0071619, PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II CTD serine 2 residues during vegetative growth" EXACT [PomBase:mah] synonym: "reduced phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2014-11-25T16:49:49Z [Term] id: FYPO:0004068 name: decreased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal." [GO:0071620, PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II CTD serine 5 residues during vegetative growth" EXACT [PomBase:mah] synonym: "reduced phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2014-11-25T16:51:53Z [Term] id: FYPO:0004069 name: abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II does not occur." [GO:0071619, PomBase:mah] synonym: "abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth" EXACT [PomBase:mah] synonym: "abolished phosphorylation of RNA polymerase II CTD serine 2 residues" EXACT [PomBase:mah] synonym: "phosphorylation of RNA polymerase II C-terminal domain serine 2 residues abolished" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2014-11-25T16:53:04Z [Term] id: FYPO:0004070 name: RNA absent from cell during cellular response to copper ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to copper ion starvation. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "RNA absent from cell during cellular response to copper ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA absent from cell during cellular response to copper ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "RNA absent from cell during cellular response to copper starvation" EXACT [PomBase:mah] synonym: "transcripts absent from cell during cellular response to copper ion starvation" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to copper ion starvation" EXACT [PomBase:mah] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth is_a: FYPO:0003280 ! decreased RNA level during cellular response to copper ion starvation during vegetative growth created_by: midori creation_date: 2014-11-27T14:03:28Z [Term] id: FYPO:0004071 name: decreased RNA level during cellular response to copper ion during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ions is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to copper ion during vegetative growth" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to copper ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcript level during cellular response to copper ion during vegetative growth" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to copper ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-11-27T14:06:20Z [Term] id: FYPO:0004072 name: RNA absent from cell during cellular response to pheromone def: "A cell phenotype in which the amount of RNA measured in a cell is too low to detect during a cellular response to a pheromone. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "transcripts absent from cell during cellular response to pheromone" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0001889 ! RNA absent from cell is_a: FYPO:0003426 ! decreased RNA level during cellular response to pheromone created_by: midori creation_date: 2014-11-27T14:20:16Z [Term] id: FYPO:0004073 name: two cell divisions prior to cell cycle arrest in mitotic G1 phase in response to pheromone def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to a pheromone occurs in G1 phase, but begins only after the cells have undergone two rounds of cell division in the presence of the pheromone." [PMID:9034336, PomBase:mah] synonym: "two cell divisions prior to cell cycle arrest in mitotic G1 phase during cellular response to pheromone" EXACT [PomBase:mah] synonym: "two cell divisions prior to mitotic cell cycle arrest in G1 phase in response to pheromone" EXACT [PomBase:mah] synonym: "two cell divisions prior to mitotic G1 arrest in response to pheromone" EXACT [PomBase:mah] synonym: "two cell divisions prior to pheromone-induced G1 arrest" EXACT [PomBase:mah] is_a: FYPO:0004074 ! delayed onset of cell cycle arrest in mitotic G1 phase in response to pheromone created_by: midori creation_date: 2014-11-27T14:27:50Z [Term] id: FYPO:0004074 name: delayed onset of cell cycle arrest in mitotic G1 phase in response to pheromone def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to a pheromone occurs in G1 phase, but begins later than normal." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "delayed cell cycle arrest in mitotic G1 phase in response to pheromone" EXACT [PomBase:mah] synonym: "delayed onset of cell cycle arrest in mitotic G1 phase during cellular response to pheromone" EXACT [PomBase:mah] synonym: "delayed onset of mitotic cell cycle arrest in G1 phase in response to pheromone" EXACT [PomBase:mah] synonym: "delayed onset of mitotic G1 arrest in response to pheromone" EXACT [PomBase:mah] synonym: "delayed onset of pheromone-induced G1 arrest" EXACT [PomBase:mah] is_a: FYPO:0000532 ! decreased mitotic cell cycle arrest in response to pheromone is_a: FYPO:0005097 ! abnormal cell cycle arrest in mitotic G1 phase created_by: midori creation_date: 2014-11-27T14:28:30Z [Term] id: FYPO:0004075 name: decreased cell growth def: "A cellular process phenotype in which cell growth is decreased. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present." [PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the 'cell population growth' terms. synonym: "reduced cell growth" EXACT [PomBase:mah] is_a: FYPO:0002862 ! abnormal cell growth created_by: midori creation_date: 2014-11-27T14:34:56Z [Term] id: FYPO:0004076 name: inviable after spore germination, single or double cell division, elongated multiseptate cell def: "A phenotype in which a spore germinates to produce a cell that is elongated, has more than one septum, and undergoes one or two rounds of cell division." [PomBase:mah] synonym: "inviable following spore germination, single or double cell division, elongated multiseptate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, elongated multiseptate cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, elongated multiseptate cell" EXACT [PomBase:mah] is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0002724 ! inviable after spore germination, single or double cell division, elongated cell created_by: midori creation_date: 2014-11-27T14:47:33Z [Term] id: FYPO:0004077 name: abnormal sporulation resulting in formation of ascus with single large spore def: "A sporulation phenotype that results in the formation of an ascus that contains a single spore that is larger than normal." [PMID:15331764, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation of ascus with single large spore" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of single-spored asci" EXACT [PomBase:mah] is_a: FYPO:0003066 ! abnormal sporulation resulting in formation of ascus with fewer than four spores relationship: output_of FYPO:0003378 ! abolished meiosis I created_by: midori creation_date: 2014-11-27T14:57:32Z [Term] id: FYPO:0004078 name: normal growth on cyclosporin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cyclosporin A." [PomBase:mah] synonym: "normal cell population growth in presence of cyclosporin A" EXACT [PomBase:mah] synonym: "normal cell population growth on cyclosporin A" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to cyclosporin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on cyclosporin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-11-27T15:00:41Z [Term] id: FYPO:0004079 name: normal histone H3-S10 phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 phosphorylation at S10 during vegetative growth" EXACT [GO:0043987] synonym: "normal histone H3-S10 phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3S10 phosphorylation during vegetative growth" EXACT [GO:0043987] is_a: FYPO:0002595 ! normal histone phosphorylation during vegetative growth created_by: midori creation_date: 2014-11-27T15:02:21Z [Term] id: FYPO:0004080 name: increased histone H3-S10 phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 is increased." [PomBase:mah] synonym: "increased histone H3 phosphorylation at S10 during vegetative growth" EXACT [GO:0043987] synonym: "increased histone H3-S10 phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3S10 phosphorylation during vegetative growth" EXACT [GO:0043987] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2014-11-27T15:05:52Z [Term] id: FYPO:0004081 name: decreased protein localization to chromatin at tRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at tRNA genes is decreased." [PMID:24945319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at tRNA genes" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at transfer RNA genes" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at tRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at tRNA genes" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0006631 ! decreased protein localization to chromatin created_by: midori creation_date: 2014-11-27T15:06:59Z [Term] id: FYPO:0004082 name: normal protein phosphorylation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-11-27T15:08:39Z [Term] id: FYPO:0004083 name: normal protein level def: "A cell phenotype in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein/peptide accumulation: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2014-11-27T15:14:06Z [Term] id: FYPO:0004084 name: normal protein level during nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein level during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "normal protein level during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal protein level during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0004083 ! normal protein level created_by: midori creation_date: 2014-11-27T15:15:19Z [Term] id: FYPO:0004085 name: decreased vegetative cell growth def: "A cellular process phenotype in which cell growth is decreased during the vegetative growth phase of the life cycle. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present." [PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the 'cell population growth' terms. synonym: "reduced vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0003154 ! abnormal vegetative cell growth is_a: FYPO:0004075 ! decreased cell growth created_by: midori creation_date: 2014-12-02T11:05:31Z [Term] id: FYPO:0004086 name: abnormal meiotic centromere clustering def: "A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions. Centromeres are normally located in one or two clusters away from the spindle pole body during meiosis." [PomBase:mah] synonym: "abnormal centromere clustering during meiosis" EXACT [GO:1990571] synonym: "abnormal chromosome retrieval during meiosis" RELATED [PomBase:vw] synonym: "abnormal kinetochore retrieval during meiosis" RELATED [Pombase:vw] synonym: "increased unclustered centromeres during meiosis" RELATED [PomBase:vw] is_a: FYPO:0004094 ! abnormal protein localization during meiotic cell cycle created_by: midori creation_date: 2014-12-02T12:59:48Z [Term] id: FYPO:0004087 name: increased number of cells with astral spindle microtubules def: "A cell population phenotype in which astral microtubules are present in a greater than normal proportion of the cells that have mitotic spindles." [PMID:11694582, PomBase:mah] synonym: "increased fraction of cells with spindles with astral microtubules" EXACT [PomBase:mah] synonym: "increased fraction of spindles with astral microtubules" EXACT [PomBase:vw] synonym: "increased number of cells with spindles with astral microtubules" EXACT [PomBase:mah] synonym: "increased number of spindles with astral microtubules" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2014-12-02T13:21:54Z [Term] id: FYPO:0004088 name: abnormal cytoplasmic microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the morphology of cytoplasmic microtubules is abnormal." [PomBase:mah] synonym: "abnormal cytoplasmic microtubule morphology" EXACT [PomBase:al] synonym: "abnormal cytoplasmic microtubule structure" NARROW [PomBase:mah] synonym: "abnormal cytoplasmic microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cytoplasmic microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2014-12-02T13:36:42Z [Term] id: FYPO:0004089 name: decreased meiotic recombination during zygotic meiosis def: "A cellular process phenotype in which the occurrence of meiotic recombination is decreased during a zygotic meiotic nuclear division. Zygotic meiosis takes place immediately after conjugation and karyogamy, without intervening vegetative growth and division of diploid cells." [PMID:11907273, PomBase:mah] synonym: "decreased meiotic recombination in zygotic nucleus" EXACT [PomBase:vw] synonym: "reduced meiotic recombination during zygotic meiosis" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2014-12-02T13:46:23Z [Term] id: FYPO:0004090 name: abnormal protein localization to microtubule cytoskeleton def: "A cell phenotype in which the localization of a protein to the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the microtubule cytoskeleton and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to microtubule cytoskeleton" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0004091 name: abolished protein localization to microtubule cytoskeleton def: "A cell phenotype in which the localization of a protein to the microtubule cytoskeleton is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "protein localization to microtubule cytoskeleton abolished" EXACT [PomBase:mah] is_a: FYPO:0004090 ! abnormal protein localization to microtubule cytoskeleton created_by: midori creation_date: 2014-12-02T14:06:34Z [Term] id: FYPO:0004092 name: abolished protein localization to horsetail-astral microtubule array def: "A cell phenotype in which the localization of a protein to the horsetail-astral microtubule array is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to horsetail-astral microtubule array" EXACT [PomBase:mah] synonym: "protein localization to horsetail-astral microtubule array abolished" EXACT [PomBase:mah] is_a: FYPO:0006130 ! abolished protein localization to microtubule during meiosis created_by: midori creation_date: 2014-12-02T14:25:33Z [Term] id: FYPO:0004093 name: normal meiotic telomere clustering def: "A meiosis phenotype in which meiotic telomere clustering is normal (i.e. indistinguishable from wild type). Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body." [GO:0045141, PomBase:mah] synonym: "normal bouquet formation" EXACT [PomBase:vw] is_a: FYPO:0006393 ! localization phenotype during meiotic cell cycle is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2014-12-02T14:35:49Z [Term] id: FYPO:0004094 name: abnormal protein localization during meiotic cell cycle def: "A cell phenotype that affects the localization of a protein in a cell during the meiotic cell cycle. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abnormal cellular protein localisation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal protein localisation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle created_by: midori creation_date: 2014-12-02T14:37:50Z [Term] id: FYPO:0004095 name: normal protein localization during meiotic cell cycle def: "A cell phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type) during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2014-12-02T14:39:40Z [Term] id: FYPO:0004096 name: normal protein localization to cytoskeleton def: "A cell phenotype in which the localization of a protein to the cytoskeleton is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoskeleton" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2014-12-02T14:43:36Z [Term] id: FYPO:0004097 name: normal actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "normal actomyosin contractile ring constriction" EXACT [PomBase:vw] synonym: "normal actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "normal contractile ring contraction" EXACT [PomBase:vw] synonym: "normal cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "normal mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "normal mitotic contractile ring contraction" EXACT [PomBase:vw] is_a: FYPO:0007827 ! normal actomyosin contractile ring organization created_by: midori creation_date: 2014-12-02T15:24:02Z [Term] id: FYPO:0004098 name: incomplete mitotic sister chromatid segregation, with phi-shaped DNA mass def: "A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and most of the DNA remains in a single mass at or near the midpoint of the mitotic spindle, but portions of the chromosomes can separate along the spindle, resulting in the formation of a DNA mass shaped like the Greek letter phi." [PMID:7957061, PomBase:mah] synonym: "incomplete mitotic sister chromatid segregation, with phi-shaped DNA mass, during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete mitotic sister chromatid separation, with phi-shaped DNA mass" RELATED [PomBase:mah] synonym: "incomplete sister chromatid segregation, with phi-shaped DNA mass during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003757 ! incomplete mitotic sister chromatid segregation created_by: midori creation_date: 2014-12-02T15:25:35Z [Term] id: FYPO:0004099 name: normal mitotic chromosome condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal chromosome condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-12-02T15:27:37Z [Term] id: FYPO:0004100 name: inviable after spore germination, without cell division, elongated cell with abnormal nuclear morphology def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, is elongated, and contains a nucleus with abnormal morphology." [PMID:7957061, PomBase:mah] comment: Abnormal chromosome morphology is usually inferred from the abnormal nuclear morphology observed in this phenotype. synonym: "inviable following spore germination, without cell division, elongated cell with abnormal chromosome morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, elongated cell with abnormal chromosome morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, elongated cell with abnormal nuclear morphology" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth is_a: FYPO:0004603 ! inviable after spore germination, without cell division, elongated cell relationship: has_part FYPO:0000062 ! abnormal nuclear morphology during vegetative growth created_by: midori creation_date: 2014-12-02T15:32:33Z [Term] id: FYPO:0004101 name: lagging mitotic chromosomes, with complete sister chromatid separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation. Although one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated, mitotic sister chromatid segregation does eventually go on to complete separation of chromosomes." [PMID:17561805, PomBase:mah] comment: Chromosome lagging may reflect a delay in detachment of sister chromatids from each other ('chromatid separation' as defined by GO:0051306), polewards movement (GO:0007079), or both. In this phenotype, both processes are eventually completed, and the overall segregation process likely completes. Consider also annotating to 'unequal mitotic sister chromatid segregation' (FYPO:0003241) or one of its descendants, because chromosomes that lag at anaphase are often missegregated at telophase. synonym: "chromosome segregation defects, lagging mitotic chromosomes, with complete sister chromatid separation" EXACT [PomBase:mah] synonym: "lagging chromosomes, with complete sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lagging chromosomes, with complete sister chromatid separation, during vegetative growth" EXACT [PomBase:mah] synonym: "lagging mitotic chromosomes, with complete chromosome separation" EXACT [PomBase:mah] synonym: "lagging mitotic sister chromatids, with complete sister chromatid separation" EXACT [PomBase:mah] is_a: FYPO:0000228 ! lagging mitotic chromosomes created_by: midori creation_date: 2014-12-02T15:38:56Z [Term] id: FYPO:0004102 name: decreased protein polyubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of polyubiquitination of one or more specific proteins, or of specific protein sites, is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein multiubiquitination during vegetative growth" EXACT [PomBase:vw] synonym: "decreased protein polyubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein polyubiquitinylation during vegetative growth" EXACT [GO:0000209, PomBase:mah] synonym: "decreased protein polyubiquitylation during vegetative growth" EXACT [GO:0000209, PomBase:mah] synonym: "reduced protein polyubiquitination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000905 ! abnormal protein ubiquitination during vegetative growth created_by: midori creation_date: 2014-12-02T15:45:22Z [Term] id: FYPO:0004103 name: viable spherical vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, and shaped in the form of a sphere." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "spherical viable cell" EXACT [PomBase:mah] synonym: "viable spherical cell" EXACT [PomBase:mah] synonym: "viable spherical cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable spherical vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000129 ! spherical vegetative cell is_a: FYPO:0002380 ! viable spheroid vegetative cell relationship: has_part FYPO:0000129 ! spherical vegetative cell created_by: midori creation_date: 2014-12-02T15:47:54Z [Term] id: FYPO:0004104 name: inviable spherical vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, and shaped in the form of a sphere." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "inviable spherical cell" EXACT [PomBase:mah] synonym: "inviable spherical cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable spherical vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; spherical vegetative cell" EXACT [PomBase:mah] synonym: "spherical inviable cell" EXACT [PomBase:mah] is_a: FYPO:0000129 ! spherical vegetative cell is_a: FYPO:0002482 ! inviable spheroid vegetative cell relationship: has_part FYPO:0000129 ! spherical vegetative cell created_by: midori creation_date: 2014-12-02T15:48:31Z [Term] id: FYPO:0004105 name: abolished polar cell growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which polar cell growth does not occur. Cells grow without polarization, instead of growing only at the ends." [PMID:8187760, PomBase:mah] synonym: "abolished polar vegetative cell growth" EXACT [PomBase:mah] synonym: "abolished polarized cell growth" EXACT [PomBase:mah] synonym: "abolished unidimensional cell growth" EXACT [PomBase:mah] synonym: "depolarized cell growth" EXACT [PomBase:mah] is_a: FYPO:0003154 ! abnormal vegetative cell growth is_a: FYPO:0005449 ! abolished cellular process created_by: midori creation_date: 2014-12-02T15:50:35Z [Term] id: FYPO:0004106 name: inviable multinucleate aseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, has no septum, and contains more than one nucleus." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable multinucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable multinucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; multinucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "multinucleate aseptate inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0003931 ! inviable aseptate vegetative cell relationship: has_part FYPO:0000061 ! multinucleate vegetative cell created_by: midori creation_date: 2014-12-02T16:29:48Z [Term] id: FYPO:0004107 name: normal protein level during mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during mitotic G2 phase" RELATED [PomBase:mah] synonym: "normal protein level during G2 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2014-12-02T16:32:23Z [Term] id: FYPO:0004108 name: increased protein level during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G1 phase of the mitotic cell cycle is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during mitotic G1 phase" RELATED [PomBase:mah] synonym: "increased protein level during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2014-12-02T16:35:52Z [Term] id: FYPO:0004109 name: delayed activation of monopolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, begins later than normal." [PomBase:mah] synonym: "delayed activation of monopolar vegetative cell growth" EXACT [PomBase:mah] synonym: "delayed onset of activation of monopolar vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0001393 ! abnormal activation of monopolar cell growth created_by: midori creation_date: 2014-12-02T16:37:34Z [Term] id: FYPO:0004110 name: normal protein level during exit from mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during exit from mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during exit from mitosis" RELATED [PomBase:mah] synonym: "normal protein level during exit from mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during mitosis to G1 transition" EXACT [PomBase:vw] synonym: "normal protein level during mitotic exit" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2014-12-02T16:49:01Z [Term] id: FYPO:0004111 name: decreased protein phosphorylation during mitotic G2 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during G2 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic G2-phase" EXACT [PomBase:vw] synonym: "decreased protein/peptide phosphorylation during mitotic G2 phase" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-12-03T11:21:10Z [Term] id: FYPO:0004112 name: increased protein phosphorylation during mitotic G2 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during G2 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during mitotic G2-phase" EXACT [PomBase:vw] synonym: "increased protein/peptide phosphorylation during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-12-03T11:22:02Z [Term] id: FYPO:0004113 name: inviable after spore germination, without cell division, small cell def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that is smaller than normal." [PomBase:mah] synonym: "inviable after spore germination, undivided small cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, small cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, small cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, small cell" EXACT [PomBase:mah] is_a: FYPO:0000951 ! inviable small vegetative cell is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology created_by: midori creation_date: 2014-12-03T11:24:29Z [Term] id: FYPO:0004114 name: inviable after spore germination, without cell division, abnormal septum morphology def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a septum with abnormal size, shape, or structure." [PMID:15116432, PomBase:mah] synonym: "inviable after spore germination, undivided cell, abnormal septum morphology" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, abnormal septum formation" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, abnormal septum morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, abnormal septum morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, abnormal septum morphology" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth relationship: has_part FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2014-12-03T11:49:43Z [Term] id: FYPO:0004115 name: inviable after spore germination, without cell division, abnormal septum morphology, enlarged nucleus def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a septum with abnormal size, shape, or structure and a nucleus that is larger than normal." [PMID:15116432, PomBase:mah] synonym: "inviable after spore germination, undivided cell, abnormal septum morphology, enlarged nucleus" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, abnormal septum formation, enlarged nucleus" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, abnormal septum morphology, enlarged nucleus" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, abnormal septum morphology, enlarged nucleus" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, abnormal septum morphology, enlarged nucleus" EXACT [PomBase:mah] is_a: FYPO:0000344 ! enlarged nucleus during vegetative growth is_a: FYPO:0004114 ! inviable after spore germination, without cell division, abnormal septum morphology relationship: has_part FYPO:0000344 ! enlarged nucleus during vegetative growth created_by: midori creation_date: 2014-12-03T11:52:09Z [Term] id: FYPO:0004116 name: inviable after spore germination, without cell division, cell enlarged around nucleus def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a diameter larger than normal only near the middle of the cell, around the nucleus." [PMID:15116432, PomBase:mah] synonym: "inviable after spore germination, undivided cell, cell enlarged around nucleus" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, cell enlarged around nucleus" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, cell enlarged around nucleus" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, cell enlarged around nucleus" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2014-12-03T11:53:10Z [Term] id: FYPO:0004117 name: inviable after spore germination, without cell division, normal septum morphology def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a septum with normal size, shape, or structure." [PMID:15116432, PomBase:mah] synonym: "inviable after spore germination, undivided cell, normal septum morphology" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, normal septum formation" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, normal septum morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, normal septum morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, normal septum morphology" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0006213 ! normal septum morphology relationship: has_part FYPO:0006213 ! normal septum morphology created_by: midori creation_date: 2014-12-03T11:55:19Z [Term] id: FYPO:0004118 name: inviable after spore germination, multiple cell divisions, normal septum morphology def: "A phenotype in which a spore germinates to produce an inviable cell that has one or more septa with normal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies." [PMID:15116432, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, normal septum morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, normal septum morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, normal septum morphology" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions is_a: FYPO:0006213 ! normal septum morphology relationship: has_part FYPO:0006213 ! normal septum morphology created_by: midori creation_date: 2014-12-03T11:56:13Z [Term] id: FYPO:0004119 name: inviable after spore germination, multiple cell divisions, elongated multinucleate cell with abnormal septum morphology def: "A phenotype in which a spore germinates to produce an inviable cell that is elongated, has more than one nucleus, has one or more septa with abnormal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies." [PMID:15116432, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, elongated multinucleate cell with abnormal septum morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, elongated multinucleate cell with abnormal septum formation" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, elongated multinucleate cell with abnormal septum morphology" EXACT [PomBase:mah] is_a: FYPO:0002262 ! inviable after spore germination, multiple cell divisions, elongated cell created_by: midori creation_date: 2014-12-03T11:57:40Z [Term] id: FYPO:0004120 name: inviable after spore germination, multiple cell divisions, small cell with abnormal septum morphology def: "A phenotype in which a spore germinates to produce an inviable cell that is smaller than normal, has a septum with abnormal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies." [PMID:15116432, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, small cell with abnormal septum formation" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, small cell with abnormal septum morphology" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, small cell with abnormal septum morphology" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, small cell with abnormal septum morphology" EXACT [PomBase:mah] is_a: FYPO:0002262 ! inviable after spore germination, multiple cell divisions, elongated cell created_by: midori creation_date: 2014-12-03T12:01:11Z [Term] id: FYPO:0004121 name: normal protein import into nucleus during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the import of protein into the nucleus is normal (i.e. indistinguishable from wild type). Import of all proteins or a specific protein may be assayed." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal nucleocytoplasmic protein import during vegetative growth" RELATED [PomBase:vw] synonym: "normal protein import into nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005397 ! normal intracellular protein transport during vegetative growth created_by: midori creation_date: 2014-12-03T12:12:16Z [Term] id: FYPO:0004122 name: obsolete cut during cellular response to thiabendazole def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to thiabendazole. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to TBZ" EXACT [CHEBI:45979, PomBase:mah] synonym: "cut during cellular response to thiabendazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to thiabendazole during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation during cellular response to thiabendazole" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2014-12-03T12:13:31Z [Term] id: FYPO:0004123 name: normal glutathione disulfide oxidoreductase activity def: "A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-12-03T12:26:59Z [Term] id: FYPO:0004124 name: decreased protein level during cellular response to cadmium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to cadmium ions is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to cadmium ion" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to cadmium" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to cadmium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to cadmium ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to cadmium ion" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-12-03T12:30:14Z [Term] id: FYPO:0004125 name: abolished histone H3-K4 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 4 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K4 dimethylation during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "abolished histone H3-K4 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K4me2 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K4 dimethylation during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "histone H3-K4 dimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K4 dimethylation absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002917 ! abolished histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2014-12-03T12:35:34Z [Term] id: FYPO:0004126 name: abolished histone H3-K4 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K4 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K4 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K4me3 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K4 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K4 trimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K4 trimethylation absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002917 ! abolished histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2014-12-03T12:37:05Z [Term] id: FYPO:0004127 name: decreased histone H3-K4 dimethylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 4 of histone H3 at protein-coding genes occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K4 dimethylation at protein coding gene during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "decreased histone H3-K4 dimethylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K4 dimethylation at protein coding gene during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K4me2 at protein coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K4 dimethylation at protein coding gene during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "reduced histone H3-K4 dimethylation at protein coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth is_a: FYPO:0002367 ! decreased histone H3-K4 dimethylation during vegetative growth created_by: midori creation_date: 2014-12-03T12:38:48Z [Term] id: FYPO:0004128 name: abnormal cysteine-type peptidase activity def: "A molecular function phenotype in which the observed rate of a cysteine-type peptidase activity is abnormal." [PomBase:mah] synonym: "abnormal caspase activity" NARROW [PomBase:mah] synonym: "abnormal cysteine protease activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-12-03T12:46:21Z [Term] id: FYPO:0004129 name: increased cysteine-type peptidase activity def: "A molecular function phenotype in which the observed rate of a cysteine-type peptidase activity is increased." [PomBase:mah] synonym: "increased caspase activity" NARROW [PomBase:mah] synonym: "increased cysteine protease activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004128 ! abnormal cysteine-type peptidase activity created_by: midori creation_date: 2014-12-03T12:46:36Z [Term] id: FYPO:0004130 name: decreased succinate dehydrogenase (ubiquinone) activity def: "A molecular function phenotype in which the observed rate of succinate dehydrogenase (ubiquinone) activity is decreased." [PomBase:mah] synonym: "reduced succinate dehydrogenase (ubiquinone) activity" EXACT [PomBase:mah] is_a: FYPO:0003322 ! abnormal succinate dehydrogenase (ubiquinone) activity created_by: midori creation_date: 2014-12-09T11:35:33Z [Term] id: FYPO:0004131 name: increased succinate dehydrogenase (ubiquinone) activity def: "A molecular function phenotype in which the observed rate of succinate dehydrogenase (ubiquinone) activity is increased." [PomBase:mah] is_a: FYPO:0003322 ! abnormal succinate dehydrogenase (ubiquinone) activity created_by: midori creation_date: 2014-12-09T11:35:44Z [Term] id: FYPO:0004132 name: normal sulfite reductase activity def: "A molecular function phenotype in which the observed rate of sulfite reductase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal sulphite reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-12-09T11:43:30Z [Term] id: FYPO:0004133 name: normal reactive oxygen species level during nitrogen starvation def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular reactive oxygen species level during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal reactive oxygen species level during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal reactive oxygen species level during nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal ROS accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "normal ROS level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2014-12-09T11:47:25Z [Term] id: FYPO:0004134 name: decreased RNA level during cellular response to diethyl maleate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to diethyl maleate is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to diethyl maleate" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to diethyl maleate" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to DEM" EXACT [PomBase:al] synonym: "decreased RNA level during cellular response to diethyl maleate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to diethyl maleate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to diethyl maleate" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to diethyl maleate" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-12-09T11:52:45Z [Term] id: FYPO:0004135 name: resistance to copper def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of copper ions than normal." [PomBase:mah] synonym: "resistance to copper during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to copper during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to copper ion" EXACT [PomBase:mah] synonym: "resistance to copper ions" EXACT [PomBase:mah] synonym: "resistant to copper" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2014-12-09T11:56:58Z [Term] id: FYPO:0004136 name: abolished histone H3-K9 dimethylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in telomeric regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at telomere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at telomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me2 at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation at telomere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished telomeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent at telomere during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0002820 ! abolished histone H3-K9 methylation at telomere during vegetative growth is_a: FYPO:0007886 ! abolished histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2014-12-09T11:58:04Z [Term] id: FYPO:0004137 name: decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a lower extent than normal." [PMID:25245948, PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at subtelomeres during vegetative growth" EXACT [PomBase:al] synonym: "decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "decreased histone H3K9me2 at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2014-12-09T12:06:04Z [Term] id: FYPO:0004138 name: increased histone H3-K9 dimethylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in telomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at telomere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at telomere during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at telomere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased telomeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2014-12-09T12:08:36Z [Term] id: FYPO:0004139 name: altered level of substance in cell during nitrogen starvation def: "A cell phenotype in which the amount of a specific substance measured in a cell that is subject to nitrogen starvation differs from normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal level of substance in cell during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2014-12-09T12:14:06Z [Term] id: FYPO:0004140 name: increased cellular glutathione level during nitrogen starvation def: "A cell phenotype in which the amount of glutathione (GSH) measured in a cell that is subject to nitrogen starvation is higher than normal." [PomBase:mah] synonym: "increased cellular glutathione level during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased cellular glutathione level during nitrogen deprivation" EXACT [PomBase:mah] synonym: "increased cellular GSH level during nitrogen starvation" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular L-gamma-glutamyl-L-cysteinylglycine level during nitrogen starvation" EXACT [CHEBI:16856] synonym: "increased cellular reduced glutathione level during nitrogen starvation" EXACT [CHEBI:16856, PomBase:al] synonym: "increased glutathione accumulation during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000990 ! increased level of substance in cell is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation created_by: midori creation_date: 2014-12-09T12:21:47Z [Term] id: FYPO:0004141 name: decreased cellular glutathione level during nitrogen starvation def: "A cell phenotype in which the amount of glutathione (GSH) measured in a cell that is subject to nitrogen starvation is lower than normal." [PomBase:mah] synonym: "decreased cellular glutathione level during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased cellular glutathione level during nitrogen deprivation" EXACT [PomBase:mah] synonym: "decreased cellular GSH level during nitrogen starvation" EXACT [CHEBI:16856, PomBase:al] synonym: "decreased cellular L-gamma-glutamyl-L-cysteinylglycine level during nitrogen starvation" EXACT [CHEBI:16856] synonym: "decreased cellular reduced glutathione level during nitrogen starvation" EXACT [CHEBI:16856, PomBase:al] synonym: "decreased glutathione accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "reduced cellular glutathione level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation created_by: midori creation_date: 2014-12-09T12:24:06Z [Term] id: FYPO:0004142 name: decreased RNA polymerase II proximal promoter sequence-specific DNA binding def: "A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. An RNA polymerase II proximal promoter is a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II." [GO:0000978, PomBase:mah] synonym: "decreased transcription factor binding to promoter region" RELATED [PomBase:al] synonym: "reduced RNA polymerase II proximal promoter sequence-specific DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2014-12-09T12:29:29Z [Term] id: FYPO:0004143 name: increased cellular nitrite level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitrite (NO2-) ions measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular nitrite accumulation" RELATED [PomBase:mah] synonym: "increased cellular nitrite ion level" EXACT [PomBase:mah] synonym: "increased cellular nitrite ion level" EXACT [PomBase:al] synonym: "increased cellular nitrite level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular nitrite level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-12-09T12:46:07Z [Term] id: FYPO:0004144 name: decreased catalase activity during cellular response to nitrosative stress def: "A molecular function phenotype in which the observed rate of catalase activity is decreased during a cellular response to nitrosative stress." [PomBase:mah] synonym: "decreased catalase activity during nitrosative stress" EXACT [PomBase:al] synonym: "reduced catalase activity during cellular response to nitrosative stress" EXACT [PomBase:mah] is_a: FYPO:0003387 ! decreased catalase activity created_by: midori creation_date: 2014-12-09T12:48:20Z [Term] id: FYPO:0004145 name: abnormal pyridoxine:NADP 4-dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyridoxine:NADP 4-dehydrogenase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-12-09T13:01:24Z [Term] id: FYPO:0004146 name: decreased pyridoxine:NADP 4-dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyridoxine:NADP 4-dehydrogenase activity is decreased." [PomBase:mah] synonym: "reduced pyridoxine:NADP 4-dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004145 ! abnormal pyridoxine:NADP 4-dehydrogenase activity created_by: midori creation_date: 2014-12-09T13:01:30Z [Term] id: FYPO:0004147 name: increased pyridoxine:NADP 4-dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyridoxine:NADP 4-dehydrogenase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004145 ! abnormal pyridoxine:NADP 4-dehydrogenase activity created_by: midori creation_date: 2014-12-09T13:01:35Z [Term] id: FYPO:0004148 name: normal pyridoxamine-phosphate oxidase activity def: "A molecular function phenotype in which the observed rate of pyridoxamine-phosphate oxidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-12-09T13:03:25Z [Term] id: FYPO:0004149 name: normal pyridoxal kinase activity def: "A molecular function phenotype in which the observed rate of pyridoxal kinase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2014-12-09T13:04:09Z [Term] id: FYPO:0004150 name: decreased cellular pyridoxamine 5'-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pyridoxamine 5'-phosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular pyridoxamine 5'-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular pyridoxamine 5'-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pyridoxamine 5'-phosphate accumulation" RELATED [PomBase:al] synonym: "reduced cellular pyridoxamine 5'-phosphate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-12-09T13:16:47Z [Term] id: FYPO:0004151 name: decreased cellular pyridoxine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pyridoxine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular pyridoxine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular pyridoxine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pyridoxine accumulation" RELATED [PomBase:al] synonym: "reduced cellular pyridoxine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-12-09T13:19:20Z [Term] id: FYPO:0004152 name: increased cellular pyridoxal level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pyridoxal measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular pyridoxal level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular pyridoxal level during vegetative growth" EXACT [PomBase:mah] synonym: "increased pyridoxal accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2014-12-09T13:20:26Z [Term] id: FYPO:0004153 name: increased flocculation in stationary phase def: "A cell population phenotype that reflects increased occurrence of flocculation when the population is in stationary phase. Flocculation is the non-sexual aggregation of single cells." [PMID:15047724, PomBase:mah] is_a: FYPO:0000155 ! increased flocculation created_by: midori creation_date: 2014-12-09T13:21:34Z [Term] id: FYPO:0004154 name: normal protein phosphorylation during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to heat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-12-09T13:37:08Z [Term] id: FYPO:0004155 name: obsolete increased protein tyrosine phosphorylation during mitotic G1 phase def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-tyrosine phosphorylation during mitotic G1 phase" EXACT [GO:0018108, PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to heat during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to heat during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased tyrosine phosphorylation during mitotic G1 phase" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0004354 created_by: midori creation_date: 2014-12-09T13:38:08Z [Term] id: FYPO:0004156 name: decreased protein level during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during mitosis" RELATED [PomBase:mah] synonym: "decreased protein level during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein level during mitotic nuclear division" EXACT [GO:0140014] synonym: "reduced protein level during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-12-09T13:42:41Z [Term] id: FYPO:0004157 name: increased protein level during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during mitosis" RELATED [PomBase:mah] synonym: "increased protein level during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein level during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2014-12-09T13:44:15Z [Term] id: FYPO:0004158 name: elongated vegetative cell with fragmented septum and more than four nuclei def: "A cell morphology phenotype in which vegetative a cell is elongated, and contains more than four nuclei and pieces of a septum that does not completely bisect the cell." [PMID:21931816, PomBase:mah] synonym: "elongated cell with fragmented septum and more than four nuclei during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated cell with fragmented septum and more than four nuclei during vegetative growth" EXACT [PomBase:mah] synonym: "long vegetative cell with fragmented septum and more than four nuclei" EXACT [PomBase:mah] is_a: FYPO:0008045 ! elongated vegetative cell with more than four nuclei created_by: midori creation_date: 2014-12-09T14:09:30Z [Term] id: FYPO:0004159 name: abnormal homologous chromosome segregation def: "A cellular process phenotype in which homologous chromosome segregation is abnormal. Homologous chromosome segregation is the process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle." [GO:0045143, PomBase:mah] synonym: "abnormal chromosome disjunction at meiosis I" EXACT [PomBase:vw] synonym: "abnormal chromosome segregation during meiosis I" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome disjunction" EXACT [PomBase:vw] synonym: "chromosome missegregation during meiosis I" RELATED [PomBase:vw] synonym: "homologous chromosome missegregation" RELATED [Pombase:vw] synonym: "meiotic chromosome missegregation" RELATED [PomBase:vw] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2014-12-09T14:12:55Z [Term] id: FYPO:0004160 name: normal meiotic spindle def: "A physical cellular phenotype in which the meiotic spindle is normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation." [PomBase:mah] synonym: "normal spindle during meiosis" EXACT [PomBase:mah] synonym: "normal spindle during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004568 ! normal spindle created_by: midori creation_date: 2014-12-09T14:23:08Z [Term] id: FYPO:0004161 name: decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at RNA polymerase II-transcribed genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at polymerase II transcribed genes during vegetative growth" EXACT [PomBase:vw] synonym: "decreased protein localization to chromatin at RNA polymerase II-regulated genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at RNA polymerase II-transcribed genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2014-12-09T14:30:07Z [Term] id: FYPO:0004162 name: loss of viability upon glucose starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to glucose starvation." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under glucose-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased viability upon glucose starvation" EXACT [PomBase:mah] synonym: "loss of cell population viability upon glucose starvation" EXACT [PomBase:mah] synonym: "loss of viability upon glucose depletion" EXACT [PomBase:al] synonym: "loss of viability upon glucose deprivation" EXACT [PomBase:mah] synonym: "loss of viability upon glucose limitation" RELATED [PomBase:mah] synonym: "reduced viability upon glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000244 ! loss of viability upon nutrient depletion created_by: midori creation_date: 2014-12-09T14:38:44Z [Term] id: FYPO:0004163 name: increased viability upon glucose starvation def: "A cell population phenotype in which a larger than normal proportion of cells in the population remains viable when cells the population are subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "increased cell population viability upon glucose starvation" EXACT [PomBase:mah] synonym: "increased viability during glucose starvation" EXACT [PomBase:mah] synonym: "increased viability upon glucose depletion" EXACT [PomBase:al] synonym: "increased viability upon glucose deprivation" EXACT [PomBase:mah] synonym: "increased viability upon glucose limitation" RELATED [PomBase:mah] is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2014-12-09T14:42:38Z [Term] id: FYPO:0004164 name: increased cellular reactive oxygen species level in stationary phase def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "increased cellular reactive oxygen species accumulation in stationary phase" RELATED [PomBase:mah] synonym: "increased cellular ROS accumulation in stationary phase" RELATED [PomBase:mah] synonym: "increased cellular ROS level in stationary phase" EXACT [PomBase:mah] synonym: "increased ROS accumulation in stationary phase" RELATED [PomBase:al] is_a: FYPO:0002142 ! altered cellular reactive oxygen species level created_by: midori creation_date: 2014-12-09T14:49:31Z [Term] id: FYPO:0004165 name: normal glucose consumption def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of glucose consumed by cells in a given time is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glucose consumption during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal glucose consumption during vegetative growth" EXACT [PomBase:mah] synonym: "normal glucose uptake" RELATED [PomBase:vw] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-12-09T14:50:40Z [Term] id: FYPO:0004166 name: increased oxygen consumption during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is higher than in wild type." [PomBase:mah] comment: Also see 'increased cellular respiration' (FYPO:0000565). synonym: "increased oxygen consumption during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased oxygen uptake during vegetative growth" RELATED [PomBase:vw] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2014-12-09T14:54:31Z [Term] id: FYPO:0004167 name: increased cell population growth on glycerol carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing glycerol as the carbon source." [PomBase:al, PomBase:mah] comment: Note that trace amounts of another carbon source are usually required for S. pombe growth on glycerol; yeast extract-based rich medium supplies the trace substance, but minimal medium must be supplemented. It is therefore important to annotate the growth medium as an experimental condition when using this term. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on glycerol carbon source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on glycerol carbon source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2014-12-09T15:00:22Z [Term] id: FYPO:0004168 name: normal viability in stationary phase during glucose starvation def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase, under conditions of glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal cell population viability in stationary phase during glucose starvation" EXACT [PomBase:mah] synonym: "normal viability in stationary phase during glucose depletion" EXACT [PomBase:mah] synonym: "normal viability in stationary phase during glucose deprivation" EXACT [PomBase:mah] synonym: "normal viability in stationary phase during glucose limitation" RELATED [PomBase:mah] is_a: FYPO:0001310 ! normal viability in stationary phase created_by: midori creation_date: 2014-12-09T15:02:19Z [Term] id: FYPO:0004169 name: decreased RNA level in stationary phase def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal when the population in which the cell is found is in stationary phase. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation in stationary phase" RELATED [PomBase:mah] synonym: "decreased transcript level in stationary phase" EXACT [PomBase:mah] synonym: "reduced RNA level in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2014-12-09T15:05:27Z [Term] id: FYPO:0004170 name: abolished histone H3-K9 dimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in centromeric regions does not occur." [PomBase:mah] synonym: "abolished centromeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromeric region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me2 at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent at centromere during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0007374 ! abnormal histone methylation at centromere during vegetative growth is_a: FYPO:0007886 ! abolished histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2014-12-09T15:23:37Z [Term] id: FYPO:0004171 name: normal RNA level during glucose starvation def: "A cell phenotype in which the amount of RNA measured in a cell that is subject to glucose starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal cellular RNA level during glucose starvation" EXACT [PomBase:mah] synonym: "normal mRNA level during glucose starvation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during glucose starvation" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "normal RNA level during glucose depletion" EXACT [PomBase:vw] synonym: "normal RNA level during glucose deprivation" EXACT [PomBase:vw] synonym: "normal RNA level during glucose limitation" RELATED [PomBase:mah] synonym: "normal transcript level during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2014-12-09T15:27:27Z [Term] id: FYPO:0004172 name: decreased protein kinase activity during cellular response to heat def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to heat." [PomBase:mah] synonym: "decreased protein kinase activity during cellular response to heat stress" EXACT [GO:0034605] synonym: "reduced protein kinase activity during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2014-12-16T14:49:39Z [Term] id: FYPO:0004173 name: decreased protein phosphorylation during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to heat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to heat stress" EXACT [GO:0034605] synonym: "reduced protein phosphorylation during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-12-16T15:05:28Z [Term] id: FYPO:0004174 name: h+ specific sterility def: "A cellular process phenotype in which conjugation does not occur in cells of the h+ mating type." [PMID:9003326, PomBase:mah] synonym: "h+-specific sterility" EXACT [PomBase:mah] synonym: "h-plus-specific mating defect" RELATED [PMID:24727291] synonym: "h-plus-specific sterility" EXACT [PomBase:mah] is_a: FYPO:0000280 ! sterile created_by: midori creation_date: 2014-12-16T15:14:55Z [Term] id: FYPO:0004175 name: decreased mating efficiency in h- cells def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal in cells of the h- mating type." [PMID:8668157, PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). synonym: "reduced mating efficiency in h- cells" EXACT [PomBase:mah] is_a: FYPO:0000708 ! decreased mating efficiency created_by: midori creation_date: 2014-12-16T15:16:01Z [Term] id: FYPO:0004176 name: decreased RNA level during cellular response to pheromone and nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to a pheromone that occurs when the cell is subject to nitrogen starvation is lower than normal. Total RNA or a specific RNA may be affected." [PMID:8668157, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to pheromone and nitrogen starvation" RELATED [PomBase:mah] synonym: "decreased transcript level during cellular response to pheromone and nitrogen starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to pheromone and nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001152 ! decreased RNA level during nitrogen starvation is_a: FYPO:0003426 ! decreased RNA level during cellular response to pheromone created_by: midori creation_date: 2014-12-16T15:26:56Z [Term] id: FYPO:0004177 name: increased RNA level during nitrogen starvation in h- cells def: "A cell phenotype in which the amount of RNA measured in a cell of the h- mating type when the cell is subject to nitrogen starvation is higher than normal. Total RNA or a specific RNA may be affected." [PMID:8668157, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation during nitrogen starvation in h- cells" RELATED [PomBase:mah] synonym: "increased RNA level during nitrogen depletion in h- cells" EXACT [PomBase:vw] synonym: "increased RNA level during nitrogen deprivation in h- cells" EXACT [PomBase:vw] synonym: "increased transcript level during nitrogen starvation in h- cells" EXACT [PomBase:vw] is_a: FYPO:0002020 ! increased RNA level during nitrogen starvation created_by: midori creation_date: 2014-12-16T15:28:56Z [Term] id: FYPO:0004178 name: increased RNA level during nitrogen starvation in h+ cells def: "A cell phenotype in which the amount of RNA measured in a cell of the h+ mating type when the cell is subject to nitrogen starvation is higher than normal. Total RNA or a specific RNA may be affected." [PMID:8668157, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation during nitrogen starvation in h+ cells" RELATED [PomBase:mah] synonym: "increased RNA level during nitrogen depletion in h+ cells" EXACT [PomBase:vw] synonym: "increased RNA level during nitrogen deprivation in h+ cells" EXACT [PomBase:vw] synonym: "increased transcript level during nitrogen starvation in h+ cells" EXACT [PomBase:vw] is_a: FYPO:0002020 ! increased RNA level during nitrogen starvation created_by: midori creation_date: 2014-12-16T15:34:31Z [Term] id: FYPO:0004179 name: decreased protein aggregate fusion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which small aggregates of misfolded protein fuse into larger aggregates to a lower extent than normal." [PMID:24936793, PomBase:mah] synonym: "decreased protein aggregate fusion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein aggregate fusion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein aggregate fusion" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2014-12-16T15:49:33Z [Term] id: FYPO:0004180 name: increased cellular protein aggregate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein present as aggregates of misfolded protein is greater than normal." [PMID:24936793, PomBase:mah] synonym: "increased cellular protein aggregate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular protein aggregate level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0008358 ! increased protein aggregate level created_by: midori creation_date: 2014-12-16T15:52:38Z [Term] id: FYPO:0004181 name: normal protein localization to cell-cell contact point during mating def: "A cell phenotype in which the localization of a protein to the region of contact between two cells undergoing conjugation is normal (i.e. indistinguishable from wild type)." [PMID:24514900, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell-cell contact point during mating" EXACT [PomBase:mah] synonym: "normal protein localization to cell-cell contact point during conjugation" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2014-12-16T15:57:02Z [Term] id: FYPO:0004182 name: normal vegetative growth on papuamide B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papuamide B." [PomBase:mah] synonym: "normal cellular response to papuamide B during vegetative growth" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth in presence of papuamide B" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on papuamide B" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative growth on papuamide B during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-12-16T16:00:05Z [Term] id: FYPO:0004183 name: normal growth on papuamide B during mating def: "A phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papuamide B when cells in the population are undergoing conjugation." [PomBase:mah] synonym: "normal cell population growth in presence of papuamide B during mating" EXACT [PomBase:mah] synonym: "normal cell population growth on papuamide B during mating" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to papuamide B during mating" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on papuamide B during conjugation with cellular fusion" EXACT [GO:0000747] is_a: FYPO:0000047 ! normal cell population growth created_by: midori creation_date: 2014-12-16T16:02:45Z [Term] id: FYPO:0004184 name: sensitive to papuamide B during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to papuamide B. Cells stop growing (and may die) at a concentration of papuamide B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to papuamide B during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to papuamide B during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2014-12-16T16:08:57Z [Term] id: FYPO:0004185 name: sensitive to myriocin during mating def: "A phenotype in which cells show increased sensitivity to myriocin during mating. Cells stop growing (and may die) at a concentration of myriocin that allows wild type cells to grow." [PMID:24514900, PomBase:mah] synonym: "sensitive to myriocin during conjugation with cellular fusion" EXACT [GO:0000747] synonym: "sensitivity to chemicals interfering with lipids during mating" BROAD [PMID:24514900] is_a: FYPO:0002683 ! increased sensitivity to chemical created_by: midori creation_date: 2014-12-16T16:10:07Z [Term] id: FYPO:0004186 name: normal vegetative growth on myriocin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing myriocin." [PomBase:mah] synonym: "normal cellular response to myriocin during vegetative growth" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth in presence of myriocin" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on myriocin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative growth on myriocin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-12-16T16:16:39Z [Term] id: FYPO:0004187 name: abolished protein export from nucleus during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein export from the nucleus does not occur during a cellular response to hydroxyurea. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein export from nucleus during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "absent protein export from nucleus during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "protein export from nucleus abolished during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "protein export from nucleus abolished during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001921 ! abolished protein export from nucleus created_by: midori creation_date: 2014-12-16T16:19:00Z [Term] id: FYPO:0004188 name: abolished protein localization to nucleus during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to HU" EXACT [PomBase:al] synonym: "abolished protein localization to nucleus during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear exclusion during cellular response to hydroxyurea" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during cellular response to hydroxyurea" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: midori creation_date: 2014-12-16T16:21:30Z [Term] id: FYPO:0004189 name: increased protein level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydroxyurea is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to HU" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2014-12-16T16:23:00Z [Term] id: FYPO:0004190 name: decreased protein level during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to ionizing radiation is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-12-16T16:25:07Z [Term] id: FYPO:0004191 name: increased RNA level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydroxyurea is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to hydroxyurea" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to HU" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to hydroxyurea" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2014-12-16T16:26:11Z [Term] id: FYPO:0004192 name: decreased RNA level during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to ionizing radiation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to ionizing radiation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-12-17T11:46:42Z [Term] id: FYPO:0004193 name: decreased protein level during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during S phase of the mitotic cell cycle is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during mitotic S phase" RELATED [PomBase:mah] synonym: "decreased protein level during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein level during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-12-17T12:02:18Z [Term] id: FYPO:0004194 name: decreased protein level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydroxyurea is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2014-12-17T12:03:24Z [Term] id: FYPO:0004195 name: normal protein localization to telomere during meiosis def: "A cell phenotype in which the localization of a protein to the telomere of a chromosome is normal (i.e. indistinguishable from wild type) during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromosome, telomeric region, during meiosis" EXACT [GO:0070198, PomBase:mah] synonym: "normal protein localisation to telomere during meiosis" EXACT [PomBase:mah] synonym: "normal protein localization to chromosome, telomeric region, during meiosis" EXACT [GO:0070198, PomBase:mah] synonym: "normal protein localization to telomere during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004095 ! normal protein localization during meiotic cell cycle created_by: midori creation_date: 2014-12-17T12:34:00Z [Term] id: FYPO:0004196 name: inviable after spore germination, single or double cell division, elongated multiseptate cell with fragmented nucleus def: "A phenotype in which a spore germinates to produce a cell that is elongated, has more than one septum and a nucleus that is broken into multiple small fragments, and undergoes one or two rounds of cell division." [PomBase:mah] synonym: "inviable after spore germination, single or double cell division, elongated multiseptate cell with fragmented nuclear DNA" RELATED [PomBase:mah] synonym: "inviable following spore germination, single or double cell division, elongated multiseptate cell with fragmented nucleus" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, elongated multiseptate cell with fragmented nucleus" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, elongated multiseptate cell with fragmented nucleus" EXACT [PomBase:mah] is_a: FYPO:0001919 ! fragmented nucleus during vegetative growth is_a: FYPO:0004076 ! inviable after spore germination, single or double cell division, elongated multiseptate cell relationship: has_part FYPO:0001919 ! fragmented nucleus during vegetative growth created_by: midori creation_date: 2014-12-17T13:22:48Z [Term] id: FYPO:0004197 name: inviable elongated cell with fragmented nucleus and mitotic cell cycle arrest in interphase def: "A cell morphology phenotype in which a vegetative cell is inviable and elongated, has a nucleus that is broken into multiple small fragments, and progression through the mitotic cell cycle is arrested in interphase. The cell contains no septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell with fragmented nucleus and mitotic cell cycle arrest in interphase during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with fragmented nucleus and cell cycle arrest in mitotic interphase" EXACT [PomBase:vw] synonym: "inviable elongated vegetative cell with fragmented nuclear DNA and mitotic cell cycle arrest in interphase" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus and mitotic interphase arrest" EXACT [PomBase:vw] synonym: "lethal; elongated vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in interphase and elongated inviable cell with fragmented nucleus" EXACT [PomBase:vw] synonym: "mitotic interphase arrested elongated inviable vegetative cell with fragmented nucleus" EXACT [PomBase:mah] is_a: FYPO:0001497 ! inviable elongated cell with mitotic cell cycle arrest in interphase is_a: FYPO:0004672 ! inviable elongated vegetative cell with fragmented nucleus relationship: has_part FYPO:0001919 ! fragmented nucleus during vegetative growth created_by: midori creation_date: 2014-12-17T13:28:37Z [Term] id: FYPO:0004198 name: decreased protein degradation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein degradation during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein degradation during mitotic nuclear division" EXACT [GO:0140014] synonym: "reduced protein degradation during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000846 ! decreased protein degradation during vegetative growth created_by: midori creation_date: 2014-12-17T13:44:14Z [Term] id: FYPO:0004199 name: increased protein degradation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein breakdown during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolic process during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolism during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein degradation during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein degradation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein degradation during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein degradation during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0000847 ! increased protein degradation during vegetative growth created_by: midori creation_date: 2014-12-17T13:46:11Z [Term] id: FYPO:0004200 name: increased protein degradation during mitotic G1 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein breakdown during mitotic G1 phase" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolic process during mitotic G1 phase" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolism during mitotic G1 phase during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein degradation during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000847 ! increased protein degradation during vegetative growth created_by: midori creation_date: 2014-12-17T13:47:17Z [Term] id: FYPO:0004201 name: decreased centromeric outer repeat transcript-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are present at lower levels than normal." [PMID:20211136, PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of RNA from the centromere outer repeat region. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. synonym: "decreased accumulation of centromeric outer repeat transcript-derived siRNA" EXACT [PomBase:mah] synonym: "decreased accumulation of siRNAs homologous to outer repeats" RELATED [PomBase:vw] synonym: "decreased centromere outer repeat transcript-derived siRNA level" EXACT [PomBase:mah] synonym: "decreased centromeric outer repeat transcript-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased centromeric outer repeat transcript-derived siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of centromeric outer repeat transcript-derived siRNA" EXACT [PomBase:mah] synonym: "decreased level of siRNAs homologous to outer repeats" EXACT [PomBase:vw] synonym: "reduced centromeric outer repeat transcript-derived siRNA level" EXACT [PomBase:mah] is_a: FYPO:0003094 ! decreased centromeric outer repeat transcript level is_a: FYPO:0004205 ! decreased siRNA level created_by: midori creation_date: 2014-12-17T14:54:21Z [Term] id: FYPO:0004202 name: decreased spliced cen-dg RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which spliced forms of RNAs transcribed from dg repeats in the centromere outer repeat region are present at lower levels than normal." [PMID:25274039, PomBase:mah] synonym: "decreased level of spliced cen-dg RNA" EXACT [PomBase:mah] synonym: "decreased level of spliced cen-dg transcripts" EXACT [PomBase:mah] synonym: "decreased level of spliced centromeric dg repeat RNA" EXACT [PomBase:mah] synonym: "decreased level of spliced centromeric dg repeat transcripts" EXACT [PomBase:mah] synonym: "decreased spliced cen-dg RNA accumulation" RELATED [PomBase:mah] synonym: "decreased spliced cen-dg RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spliced cen-dg RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spliced cen-dg transcript level" EXACT [PomBase:mah] synonym: "reduced spliced cen-dg RNA level" EXACT [PomBase:mah] is_a: FYPO:0003094 ! decreased centromeric outer repeat transcript level created_by: midori creation_date: 2014-12-17T14:57:59Z [Term] id: FYPO:0004203 name: increased calcium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased calcium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased calcium import during vegetative growth" EXACT [PomBase:mah] synonym: "increased calcium import into cell" EXACT [PomBase:mah] synonym: "increased calcium ion import" EXACT [PomBase:mah] synonym: "increased calcium ion import across plasma membrane" EXACT [GO:0098703] synonym: "increased calcium uptake" EXACT [PomBase:mah] synonym: "increased calcium uptake into intracellular compartments" RELATED [PomBase:vw] synonym: "increased cellular calcium import" EXACT [PomBase:al] is_a: FYPO:0001953 ! abnormal calcium import created_by: midori creation_date: 2014-12-17T15:05:32Z [Term] id: FYPO:0004204 name: decreased mature snRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature small nuclear RNA level" EXACT [PomBase:mah] synonym: "decreased mature snRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature snRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature snRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature snRNA transcript level" BROAD [PomBase:vw] synonym: "decreased snRNA level" BROAD [PomBase:mah] synonym: "reduced mature snRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005997 ! altered snRNA or precursor level created_by: midori creation_date: 2014-12-19T10:48:11Z [Term] id: FYPO:0004205 name: decreased siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature siRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature siRNA level" EXACT [PomBase:mah] synonym: "decreased siRNA accumulation" RELATED [PomBase:mah] synonym: "decreased siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased siRNA transcript level" EXACT [PomBase:mah] synonym: "decreased small interfering RNA level" EXACT [PomBase:mah] synonym: "reduced siRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2014-12-19T10:49:16Z [Term] id: FYPO:0004206 name: increased mature snRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snRNA measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mature small nuclear RNA level" EXACT [PomBase:mah] synonym: "increased mature snRNA accumulation" RELATED [PomBase:mah] synonym: "increased mature snRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature snRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature snRNA transcript level" BROAD [PomBase:vw] synonym: "increased snRNA level" BROAD [PomBase:mah] is_a: FYPO:0005997 ! altered snRNA or precursor level is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2014-12-19T10:50:02Z [Term] id: FYPO:0004207 name: increased siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature siRNA measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mature siRNA level" EXACT [PomBase:mah] synonym: "increased siRNA accumulation" RELATED [PomBase:mah] synonym: "increased siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased siRNA transcript level" EXACT [PomBase:mah] synonym: "increased small interfering RNA level" EXACT [PomBase:mah] is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2014-12-19T10:50:41Z [Term] id: FYPO:0004208 name: abnormal histone methyltransferase activity (H3-K4 specific) def: "A molecular function phenotype in which the observed rate of H3-K4 specific histone methyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal H3-K4 specific histone methyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2014-12-19T11:30:25Z [Term] id: FYPO:0004209 name: abolished histone methyltransferase activity (H3-K4 specific) def: "A molecular function phenotype in which H3-K4 specific histone methyltransferase activity is absent." [PomBase:mah] synonym: "histone methyltransferase activity (H3-K4 specific) abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004208 ! abnormal histone methyltransferase activity (H3-K4 specific) created_by: midori creation_date: 2014-12-19T11:30:30Z [Term] id: FYPO:0004210 name: mitotic spindle elongation without chromosome separation with centromeric DNA dissociated from spindle def: "A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes, DNA remains in a single mass at or near the midpoint of the mitotic spindle, and centromeric DNA is not closely associated with the mitotic spindle." [PMID:16855021, PomBase:mah, PomBase:vw] synonym: "incomplete mitotic sister chromatid segregation, with unseparated DNA and centromeric DNA dissociated from spindle" EXACT [PomBase:mah] synonym: "mitotic spindle elongation without chromosome separation with centromeric DNA dissociated from spindle during vegetative growth" EXACT [PomBase:mah] synonym: "spindle elongation without chromosome separation with centromeric DNA dissociated from spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003758 ! mitotic spindle elongation without chromosome separation created_by: midori creation_date: 2014-12-19T12:42:19Z [Term] id: FYPO:0004211 name: mitotic spindle elongation without chromosome separation with centromeric DNA associated with spindle def: "A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes, DNA remains in a single mass at or near the midpoint of the mitotic spindle, and centromeric DNA is closely associated with the mitotic spindle." [PomBase:mah, PomBase:vw] synonym: "incomplete mitotic sister chromatid segregation, with unseparated DNA and centromeric DNA associated with spindle" EXACT [PomBase:mah] synonym: "mitotic spindle elongation without chromosome separation with centromeric DNA associated with spindle during vegetative growth" EXACT [PomBase:mah] synonym: "spindle elongation without chromosome separation with centromeric DNA associated with spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003758 ! mitotic spindle elongation without chromosome separation created_by: midori creation_date: 2014-12-19T12:51:21Z [Term] id: FYPO:0004212 name: decreased protein localization to kinetochore during meiosis I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is decreased during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to kinetochore during meiosis I" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic kinetochore during meiosis I" EXACT [PomBase:vw] synonym: "reduced protein localization to kinetochore during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0004762 ! abnormal protein localization to kinetochore during meiosis created_by: midori creation_date: 2014-12-19T13:00:18Z [Term] id: FYPO:0004213 name: abnormal attachment of mitotic spindle microtubules to kinetochore def: "A cellular process phenotype in which the physical attachment of sister chromatids to mitotic spindle microtubules is abnormal." [PomBase:mah] comment: This term is less specific than 'abnormal mitotic sister chromatid biorientation' (FYPO:0000326) because sister chromatid biorientation normally occurs only as part of metaphase plate congression, not during other stages of mitosis. FYPO:0004213 can be used for abnormal attachment observed at any time during mitosis. synonym: "abnormal attachment of mitotic spindle microtubules to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2014-12-19T13:09:48Z [Term] id: FYPO:0004214 name: normal protein localization to kinetochore during meiosis I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis is_a: FYPO:0005042 ! normal protein localization to kinetochore created_by: midori creation_date: 2014-12-19T13:43:10Z [Term] id: FYPO:0004215 name: abnormal histone H4-K20 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 20 of histone H4 is abnormal." [PomBase:mah] synonym: "abnormal histone H4 K20 methylation during vegetative growth" EXACT [GO:0034770, PomBase:mah] synonym: "abnormal histone H4-K20 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H4K20me during vegetative growth" EXACT [GO:0034770, PomBase:mah] synonym: "abnormal histone lysine H4 K20 methylation during vegetative growth" EXACT [GO:0034770, PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2014-12-19T14:50:23Z [Term] id: FYPO:0004216 name: abolished histone H4-K20 monomethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 does not occur." [PomBase:mah] synonym: "abolished histone H4 K20 monomethylation during vegetative growth" EXACT [GO:0034771, PomBase:mah] synonym: "abolished histone H4-K20 monomethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H4K20me1 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H4 K20 monomethylation during vegetative growth" EXACT [GO:0034771, PomBase:mah] synonym: "histone H4-K20 monomethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H4-K20 monomethylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0008179 ! decreased histone H4-K20 monomethylation during vegetative growth created_by: midori creation_date: 2014-12-19T14:52:43Z [Term] id: FYPO:0004217 name: abolished histone H4-K20 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 does not occur." [PomBase:mah] synonym: "abolished histone H4 K20 dimethylation during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "abolished histone H4-K20 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H4K20me2 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H4 K20 dimethylation during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "histone H4-K20 dimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H4-K20 dimethylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0002565 ! abolished histone methylation during vegetative growth is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:00:01Z [Term] id: FYPO:0004218 name: abolished histone H4-K20 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 does not occur." [PomBase:mah] synonym: "abolished histone H4 K20 trimethylation during vegetative growth" EXACT [GO:0034773, PomBase:mah] synonym: "abolished histone H4-K20 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H4K20me3 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H4 K20 trimethylation during vegetative growth" EXACT [GO:0034773, PomBase:mah] synonym: "histone H4-K20 trimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H4-K20 trimethylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0002565 ! abolished histone methylation during vegetative growth is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:04:26Z [Term] id: FYPO:0004219 name: normal histone H4-K20 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H4 K20 methylation during vegetative growth" EXACT [GO:0034470, PomBase:mah] synonym: "normal histone H4-K20 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H4K20me during vegetative growth" EXACT [GO:0034770, PomBase:mah] synonym: "normal histone lysine H4 K20 methylation during vegetative growth" EXACT [GO:0034770, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:15:59Z [Term] id: FYPO:0004220 name: normal histone H4-K20 monomethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H4 K20 monomethylation during vegetative growth" EXACT [GO:0034471, PomBase:mah] synonym: "normal histone H4-K20 monomethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H4K20me1 during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H4 K20 monomethylation during vegetative growth" EXACT [GO:0034771, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:17:45Z [Term] id: FYPO:0004221 name: normal histone H4-K20 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H4 K20 dimethylation during vegetative growth" EXACT [GO:0034472, PomBase:mah] synonym: "normal histone H4-K20 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H4K20me2 during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H4 K20 dimethylation during vegetative growth" EXACT [GO:0034772, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:19:09Z [Term] id: FYPO:0004222 name: normal histone H4-K20 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H4 K20 trimethylation during vegetative growth" EXACT [GO:0034473, PomBase:mah] synonym: "normal histone H4-K20 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H4K20me3 during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H4 K20 trimethylation during vegetative growth" EXACT [GO:0034773, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:20:23Z [Term] id: FYPO:0004223 name: increased histone H4-K20 monomethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K20 monomethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K20 monomethylation during vegetative growth" EXACT [GO:0034771, PomBase:mah] synonym: "increased histone H4K20me1 during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H4-K20 monomethylation during vegetative growth" EXACT [GO:0034771, PomBase:mah] is_a: FYPO:0000869 ! increased histone methylation during vegetative growth is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:21:57Z [Term] id: FYPO:0004224 name: decreased histone H4-K20 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased H4K20me3 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H4-K20 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4K20 trimethylation during vegetative growth" EXACT [GO:0034773, PomBase:mah] synonym: "decreased histone lysine H4-K20 trimethylation during vegetative growth" EXACT [GO:0034773, PomBase:mah] synonym: "reduced histone H4-K20 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:22:07Z [Term] id: FYPO:0004225 name: abnormal nucleosome binding def: "A molecular function phenotype in which occurrence of nucleosome binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a nucleosome that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2014-12-19T15:30:06Z [Term] id: FYPO:0004226 name: abolished nucleosome binding def: "A molecular function phenotype in which nucleosome binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "nucleosome binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0004225 ! abnormal nucleosome binding created_by: midori creation_date: 2014-12-19T15:30:10Z [Term] id: FYPO:0004227 name: decreased nucleosome binding def: "A molecular function phenotype in which occurrence of nucleosome binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced nucleosome binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0004225 ! abnormal nucleosome binding created_by: midori creation_date: 2014-12-19T15:30:29Z [Term] id: FYPO:0004228 name: decreased protein phosphorylation during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:34:43Z [Term] id: FYPO:0004229 name: normal growth during cellular response to ionizing radiation def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to ionizing radiation." [PomBase:mah] synonym: "normal cell population growth during cellular response to ionizing radiation" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth during cellular response to IR" EXACT [PomBase:mah] synonym: "normal cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "normal sensitivity to ionizing radiation" RELATED [PomBase:vw] synonym: "normal vegetative cell population growth during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2014-12-19T15:38:05Z [Term] id: FYPO:0004230 name: normal protein phosphorylation during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to ultraviolet light" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2014-12-19T15:40:25Z [Term] id: FYPO:0004231 name: abnormal methylated histone binding def: "A molecular function phenotype in which occurrence of methylated histone binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds one or more methylated histone(s) differently from wild type, or that a mutation in one gene affects methylated histone binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0007157 ! abnormal histone binding created_by: midori creation_date: 2014-12-19T15:44:56Z [Term] id: FYPO:0004232 name: abolished methylated histone binding def: "A molecular function phenotype in which methylated histone binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "methylated histone binding abolished" EXACT [PomBase:mah] is_a: FYPO:0004231 ! abnormal methylated histone binding created_by: midori creation_date: 2014-12-19T15:45:21Z [Term] id: FYPO:0004233 name: decreased and delayed cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but its occurrence is decreased and begins later than normal." [PMID:21118960, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "decreased and delayed cell cycle arrest in mitotic G1 phase during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased and delayed cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased and delayed cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased and delayed mitotic cell cycle arrest in G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased and delayed mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased and delayed nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] synonym: "reduced and delayed cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000712 ! delayed onset of cell cycle arrest in mitotic G1 phase in response to nitrogen starvation created_by: midori creation_date: 2014-12-19T15:53:01Z [Term] id: FYPO:0004235 name: normal RNA level oscillation during mitotic cell cycle def: "A gene expression phenotype in which RNA levels vary over the course of the mitotic cell cycle normally (i.e. levels are indistinguishable from wild type at any assayed point). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:21118960, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal periodic expression of RNA during mitotic cell cycle" EXACT [PomBase:al] synonym: "normal RNA level fluctuation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal transcript level oscillation during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth created_by: midori creation_date: 2014-12-19T16:08:33Z [Term] id: FYPO:0004236 name: thin mitotic spindle midzone def: "A spindle phenotype in which the mitotic spindle is not of uniform thickness, but instead the spindle midzone is thinner than normal." [PMID:17442892, PomBase:mah] synonym: "decreased mitotic spindle midzone thickness" EXACT [PomBase:mah] synonym: "thin mitotic spindle midzone during vegetative growth" EXACT [PomBase:mah] synonym: "thin spindle midzone during mitosis" EXACT [PomBase:mah] synonym: "thin spindle midzone during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2014-12-19T16:21:43Z [Term] id: FYPO:0004237 name: increased protein localization to heterochromatin at centromere outer repeat region def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions of a chromosome is decreased." [PMID:20299449, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to heterochromatin at centromere otr" EXACT [PomBase:mah] synonym: "increased protein localisation to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "increased protein localisation to heterochromatin at pericentric region" RELATED [PomBase:mah] synonym: "increased protein localisation to heterochromatin at pericentromeric region" RELATED [PomBase:mah] synonym: "increased protein localiszation to heterochromatin at centromeric outer repeat" EXACT [PomBase:mah] synonym: "increased protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to heterochromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001131 ! abnormal protein localization to heterochromatin during vegetative growth is_a: FYPO:0003009 ! increased protein localization to centromere outer repeat is_a: FYPO:0004380 ! increased protein localization to pericentric heterochromatin during vegetative growth created_by: midori creation_date: 2015-01-07T10:46:02Z [Term] id: FYPO:0004238 name: increased histone H3-K4 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K4 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K4 acetylation during vegetative growth" EXACT [GO:0043973] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth created_by: midori creation_date: 2015-01-07T11:15:51Z [Term] id: FYPO:0004239 name: decreased histone H3-K4 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3-K4 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K4 acetylation during vegetative growth" EXACT [GO:0043973] synonym: "reduced histone H3-K4 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2015-01-07T11:17:08Z [Term] id: FYPO:0004240 name: decreased histone H3-K56 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3-K56 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K56 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K56 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2015-01-07T11:18:00Z [Term] id: FYPO:0004241 name: decreased rate of DNA replication during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA replication is decreased during a cellular response to DNA damage." [PomBase:mah] synonym: "decreased rate of DNA replication during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of DNA replication during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of DNA replication in response to DNA damage" RELATED [PomBase:vw] synonym: "reduced rate of DNA replication during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0001982 ! decreased rate of DNA replication during vegetative growth created_by: midori creation_date: 2015-01-07T11:21:55Z [Term] id: FYPO:0004242 name: decreased protein kinase activity during mitotic S phase def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the S phase of the mitotic cell cycle." [PomBase:mah] synonym: "reduced protein kinase activity during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0003331 ! decreased protein kinase activity during mitotic interphase created_by: midori creation_date: 2015-01-07T11:52:30Z [Term] id: FYPO:0004243 name: decreased protein kinase activity during cellular response to DNA damage def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to DNA damage." [PomBase:mah] synonym: "decreased protein kinase activity in response to DNA damage" RELATED [PomBase:vw] synonym: "reduced protein kinase activity during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2015-01-07T12:02:39Z [Term] id: FYPO:0004244 name: decreased protein kinase activity during mitotic S phase during cellular response to DNA damage def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during S phase of the mitotic cell cycle during a cellular response to DNA damage." [PomBase:mah] synonym: "decreased protein kinase activity during mitotic S phase in response to DNA damage" RELATED [PomBase:vw] synonym: "reduced protein kinase activity during mitotic S phase during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0004242 ! decreased protein kinase activity during mitotic S phase is_a: FYPO:0004243 ! decreased protein kinase activity during cellular response to DNA damage created_by: midori creation_date: 2015-01-07T12:03:45Z [Term] id: FYPO:0004245 name: normal protein kinase activity during mitotic S phase during cellular response to DNA damage def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle during a cellular response to DNA damage." [PomBase:mah] synonym: "normal protein kinase activity during mitotic S phase in response to DNA damage" RELATED [PomBase:vw] is_a: FYPO:0003075 ! normal protein kinase activity created_by: midori creation_date: 2015-01-07T12:10:54Z [Term] id: FYPO:0004246 name: abnormal microtubule cytoskeleton morphology during meiotic prophase I def: "A physical cellular phenotype in which the size, shape, or structure of the microtubule cytoskeleton is abnormal during prophase of the first meiotic nuclear division." [PMID:11907273, PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. synonym: "abnormal microtubule cytoskeleton morphology during prophase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003064 ! abnormal microtubule cytoskeleton morphology created_by: midori creation_date: 2015-01-07T12:18:35Z [Term] id: FYPO:0004247 name: normal vacuolar morphology during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type vacuole is normal (i.e. indistinguishable from wild type).." [PomBase:mah] synonym: "normal vacuolar morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vacuole morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2015-01-07T13:07:33Z [Term] id: FYPO:0004248 name: normal protein localization to vacuolar membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to vacuolar membrane" EXACT [PomBase:mah] synonym: "normal protein localization in vacuolar membrane" EXACT [GO:1903778] synonym: "normal protein localization to vacuolar membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to vacuolar membrane during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to vacuole membrane" EXACT [PomBase:mah] is_a: FYPO:0007058 ! normal protein localization to vacuole created_by: midori creation_date: 2015-01-07T13:16:32Z [Term] id: FYPO:0004249 name: abnormal protein localization to vacuolar membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to vacuolar membrane" EXACT [PomBase:mah] synonym: "abnormal protein localization in vacuolar membrane" EXACT [GO:1903778] synonym: "abnormal protein localization to vacuolar membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to vacuolar membrane during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to vacuole membrane" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2015-01-07T13:18:23Z [Term] id: FYPO:0004250 name: abolished protein localization to vacuolar membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to vacuolar membrane" EXACT [PomBase:mah] synonym: "abolished protein localization in vacuolar membrane" EXACT [GO:1903778] synonym: "abolished protein localization to vacuolar membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to vacuolar membrane during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to vacuole membrane" EXACT [PomBase:mah] synonym: "protein localization to vacuolar membrane abolished" EXACT [PomBase:mah] is_a: FYPO:0004249 ! abnormal protein localization to vacuolar membrane created_by: midori creation_date: 2015-01-07T13:18:29Z [Term] id: FYPO:0004251 name: increased DNA resection during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the extent of DNA resection upstream of a stalled replication fork is greater than normal. DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA." [PMID:20051983, PMID:24806966, PomBase:mah] synonym: "increased DNA resection during replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA resection during replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "increased DNA resectioning during replication fork processing" EXACT [PomBase:amc] synonym: "increased extent of DNA resection during replication fork processing" EXACT [PomBase:mah] synonym: "increased extent of exonucleolytic DNA cleavage during replication fork processing" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2015-01-07T14:13:46Z [Term] id: FYPO:0004252 name: normal regulation of DNA replication during replication fork arrest def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of DNA replication is normal (i.e. indistinguishable from wild type) when one or more replication forks arrest." [PMID:24806966, PomBase:mah] synonym: "normal regulation of DNA replication during replication fork arrest during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal regulation of DNA replication during replication fork arrest during vegetative growth" EXACT [PomBase:mah] synonym: "normal regulation of nuclear cell cycle DNA replication during replication fork arrest" EXACT [GO:0033262] is_a: FYPO:0002995 ! normal regulation of DNA replication created_by: midori creation_date: 2015-01-07T14:53:56Z [Term] id: FYPO:0004253 name: decreased nuclease activity def: "A molecular function phenotype in which the observed rate of a nuclease activity is decreased." [PomBase:mah] synonym: "reduced nuclease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0003163 ! abnormal nuclease activity created_by: midori creation_date: 2015-01-07T15:00:06Z [Term] id: FYPO:0004254 name: abnormal mitotic cell cycle regulation during cellular response to UV def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to UV. The most common abnormality is for the cell cycle to progress as in the absence of UV exposure." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to UV" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to UV during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following UV exposure" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to UV" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2015-01-07T15:01:50Z [Term] id: FYPO:0004255 name: inviable elongated mononucleate vegetative cell def: "A cell phenotype in which a cell contains one nucleus, is elongated, and is inviable." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable elongated mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable long mononucleate vegetative cell" EXACT [PomBase:vw] synonym: "inviable vegetative elongated mononucleate cell" EXACT [PomBase:mah] synonym: "lethal; elongated mononucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0001916 ! elongated mononucleate vegetative cell is_a: FYPO:0006430 ! inviable mononucleate vegetative cell created_by: midori creation_date: 2015-01-07T15:09:10Z [Term] id: FYPO:0004256 name: viable lemon-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell is viable, and grows in the form of a lemon. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc." [http://mathworld.wolfram.com/Lemon.html, PomBase:mah] synonym: "viable lemon-shaped cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable lemon-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable lemon-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000224 ! lemon-shaped cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape relationship: has_part FYPO:0000224 ! lemon-shaped cell created_by: midori creation_date: 2015-01-07T15:34:48Z [Term] id: FYPO:0004257 name: swollen multinucleate vegetative cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus and has a larger volume than normal." [PMID:10503548, PomBase:mah] synonym: "enlarged multinucleate cell" RELATED [PomBase:mah] synonym: "large multinucleate cell" RELATED [PomBase:vw] synonym: "multinucleate cell with increased cell size" RELATED [PomBase:vw] synonym: "multinucleate cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "swollen multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0000646 ! swollen vegetative cell relationship: has_part FYPO:0000061 ! multinucleate vegetative cell relationship: has_part FYPO:0000646 ! swollen vegetative cell created_by: midori creation_date: 2015-01-07T15:46:08Z [Term] id: FYPO:0004258 name: obsolete decreased protein tyrosine phosphorylation during cellular response to hydroxyurea def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydroxyurea." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased peptidyl-tyrosine phosphorylation during cellular response to hydroxyurea" EXACT [GO:0018108, PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein tyrosine phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tyrosine phosphorylation during cellular response to hydroxyurea" EXACT [PomBase:al] synonym: "reduced protein tyrosine phosphorylation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002098 created_by: midori creation_date: 2015-01-07T15:58:13Z [Term] id: FYPO:0004259 name: abolished mitotic G2 DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic G2 DNA damage checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage." [GO:0007095, PMID:21098122, PomBase:mah] synonym: "abolished G2 DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished mitotic cell cycle G2/M transition DNA damage checkpoint" EXACT [GO:0007095] synonym: "abolished mitotic G2 DNA damage checkpoint activation" RELATED [PomBase:mah] synonym: "abolished mitotic G2 DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic G2 DNA damage checkpoint abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004373 ! abnormal mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2015-01-07T16:18:15Z [Term] id: FYPO:0004260 name: increased duration of protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the region of a chromosome at which a DNA double-strand break has occurred for longer than normal." [PMID:21098122, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "increased duration of protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to DSB site" EXACT [PomBase:al] synonym: "increased duration of protein localization to site of double-strand break" EXACT [GO:0035861, PomBase:mah] synonym: "prolonged protein localization to double-strand break site" EXACT [PomBase:mah] is_a: FYPO:0002473 ! abnormal protein localization to double-strand break site created_by: midori creation_date: 2015-01-07T16:34:48Z [Term] id: FYPO:0004261 name: decreased protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during G2 phase of the mitotic cell cycle and during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to ionizing radiation during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to ionizing radiation during mitotic G2 phase" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic G2 phase during cellular response to IR" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitotic G2 phase during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0002470 ! decreased protein phosphorylation during cellular response to ionizing radiation is_a: FYPO:0004111 ! decreased protein phosphorylation during mitotic G2 phase created_by: midori creation_date: 2015-01-07T16:38:24Z [Term] id: FYPO:0004262 name: abolished protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during G2 phase of the mitotic cell cycle and during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to ionizing radiation during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to ionizing radiation during mitotic G2 phase" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during mitotic G2 phase during cellular response to IR" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during mitotic G2 phase during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0002471 ! abolished protein phosphorylation during cellular response to ionizing radiation created_by: midori creation_date: 2015-01-07T16:41:21Z [Term] id: FYPO:0004263 name: normal viability in stationary phase during nitrogen limitation def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase, under conditions of nitrogen limitation, such as in a medium that contains a low level of NH4Cl and no other nitrogen source." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to nitrogen limitation in culture. Note that nitrogen limitation differs from nitrogen starvation in that starvation results from complete absence of nitrogen, whereas limitation results from a shift from high to low nitrogen levels. synonym: "normal cell population viability in stationary phase during nitrogen limitation" EXACT [PomBase:mah] is_a: FYPO:0001310 ! normal viability in stationary phase created_by: midori creation_date: 2015-01-07T16:52:15Z [Term] id: FYPO:0004264 name: decreased cAMP-dependent protein kinase activity def: "A molecular function phenotype in which the observed rate of cAMP-dependent protein kinase activity is decreased." [PomBase:mah] synonym: "reduced cAMP-dependent protein kinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2015-01-07T16:56:02Z [Term] id: FYPO:0004265 name: abnormal protein localization to cortical microtubule cytoskeleton def: "A cell phenotype in which the localization of a protein to the cortical microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the cortical microtubule cytoskeleton and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cortical microtubule cytoskeleton" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2015-01-14T12:28:35Z [Term] id: FYPO:0004266 name: abolished protein localization to cortical microtubule cytoskeleton def: "A cell phenotype in which the localization of a protein to the cortical microtubule cytoskeleton does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cortical microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "protein absent from cortical microtubule cytoskeleton" RELATED [PomBase:mah] synonym: "protein localization to cortical microtubule cytoskeleton abolished" EXACT [PomBase:mah] is_a: FYPO:0004265 ! abnormal protein localization to cortical microtubule cytoskeleton created_by: midori creation_date: 2015-01-14T12:34:09Z [Term] id: FYPO:0004267 name: normal septum disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum disassembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal septum disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septum disassembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-01-14T12:55:16Z [Term] id: FYPO:0004268 name: decreased septum disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of septum disassembly is decreased." [PomBase:mah] synonym: "decreased septum disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased septum disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced septum disassembly" EXACT [PomBase:mah] is_a: FYPO:0000132 ! abnormal septum disassembly created_by: midori creation_date: 2015-01-14T13:09:37Z [Term] id: FYPO:0004269 name: abnormal cell septum edging catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dissolution of the cell septum edging material is abnormal; may result in the formation of chains of attached cells." [PomBase:mah] synonym: "abnormal cell septum edging catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cell septum edging catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell septum edging catabolism" EXACT [PomBase:mah] synonym: "abnormal cell septum edging hydrolysis" EXACT [GO:0030995] synonym: "chained cells" RELATED [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2015-01-14T13:18:47Z [Term] id: FYPO:0004270 name: decreased cell septum edging catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dissolution of the cell septum edging material is decreased." [PomBase:mah] synonym: "decreased cell septum edging catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell septum edging catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cell septum edging hydrolysis" EXACT [GO:030995] synonym: "reduced cell septum edging catabolic process" EXACT [PomBase:mah] is_a: FYPO:0004269 ! abnormal cell septum edging catabolic process created_by: midori creation_date: 2015-01-14T13:18:53Z [Term] id: FYPO:0004271 name: normal cell septum edging catabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dissolution of the cell septum edging material is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell septum edging catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell septum edging catabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell septum edging catabolism" EXACT [PomBase:mah] synonym: "normal cell septum edging hydrolysis" EXACT [GO:0030995] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-01-14T13:22:29Z [Term] id: FYPO:0004272 name: abnormal ascospore release from ascus def: "A cellular process phenotype in which ascospore release from an ascus is abnormal." [GO:0071998, PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2015-01-14T13:27:27Z [Term] id: FYPO:0004273 name: decreased ascospore release from ascus def: "A cellular process phenotype in which the occurrence of ascospore release from an ascus is decreased." [GO:0071998, PomBase:mah] synonym: "reduced ascospore release from ascus" EXACT [PomBase:mah] is_a: FYPO:0004272 ! abnormal ascospore release from ascus created_by: midori creation_date: 2015-01-14T13:27:37Z [Term] id: FYPO:0004274 name: abolished ascospore release from ascus def: "A cellular process phenotype in which ascospore release from an ascus does not occur." [GO:0071998, PomBase:mah] synonym: "absent ascospore release from ascus" EXACT [PomBase:mah] synonym: "ascospore release from ascus abolished" EXACT [PomBase:mah] is_a: FYPO:0004272 ! abnormal ascospore release from ascus created_by: midori creation_date: 2015-01-14T13:27:37Z [Term] id: FYPO:0004275 name: abnormal positive regulation of transcription during G0 def: "A transcription regulation phenotype in which any process of positive regulation of transcription is abnormal during G0 phase." [PomBase:mah] synonym: "abnormal activation of gene-specific transcription during G0" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal activation of transcription, DNA-dependent, during G0" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of cellular transcription, DNA-dependent, during G0" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of gene-specific transcription during G0" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of transcription during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal positive regulation of transcription during quiescence" EXACT [PomBase:mah] synonym: "abnormal positive regulation of transcription, DNA-dependent, during G0" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal stimulation of gene-specific transcription during G0" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal stimulation of transcription, DNA-dependent, during G0" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal up regulation of gene-specific transcription during G0" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal up regulation of transcription, DNA-dependent, during G0" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal up-regulation of gene-specific transcription during G0" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal up-regulation of transcription, DNA-dependent during G0" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal upregulation of gene-specific transcription during G0" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal upregulation of transcription, DNA-dependent, during G0" EXACT [GO:0045893, PomBase:mah] is_a: FYPO:0000623 ! abnormal positive regulation of transcription created_by: midori creation_date: 2015-01-14T13:32:28Z [Term] id: FYPO:0004276 name: abnormal negative regulation of transcription during G0 def: "A transcription regulation phenotype in which any process of negative regulation of transcription is abnormal during G0 phase." [PomBase:mah] synonym: "abnormal down regulation of gene-specific transcription during G0" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal down regulation of transcription, DNA-dependent, during G0" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal down-regulation of gene-specific transcription during G0" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal down-regulation of transcription, DNA-dependent, during G0" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal downregulation of gene-specific transcription during G0" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal downregulation of transcription, DNA-dependent, during G0" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal inhibition of gene-specific transcription during G0" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal inhibition of transcription, DNA-dependent, during G0" NARROW [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of cellular transcription, DNA-dependent, during G0" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of gene-specific transcription during G0" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of transcription during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal negative regulation of transcription during quiescence" EXACT [PomBase:mah] synonym: "abnormal negative regulation of transcription, DNA-dependent, during G0" EXACT [GO:0045892, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype created_by: midori creation_date: 2015-01-14T13:34:50Z [Term] id: FYPO:0004277 name: abnormal uracil DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of uracil DNA N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:44:14Z [Term] id: FYPO:0004278 name: decreased uracil DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of uracil DNA N-glycosylase activity is decreased." [PomBase:mah] synonym: "reduced uracil DNA N-glycosylase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004277 ! abnormal uracil DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:44:21Z [Term] id: FYPO:0004279 name: abnormal hypoxanthine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of hypoxanthine DNA N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:46:33Z [Term] id: FYPO:0004280 name: decreased hypoxanthine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of hypoxanthine DNA N-glycosylase activity is decreased." [PomBase:mah] synonym: "reduced hypoxanthine DNA N-glycosylase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004279 ! abnormal hypoxanthine DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:46:42Z [Term] id: FYPO:0004281 name: abnormal xanthine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of xanthine DNA N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:47:41Z [Term] id: FYPO:0004282 name: decreased xanthine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of xanthine DNA N-glycosylase activity is decreased." [PomBase:mah] synonym: "reduced xanthine DNA N-glycosylase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004281 ! abnormal xanthine DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:47:45Z [Term] id: FYPO:0004283 name: abnormal oxanine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of oxanine DNA N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:48:23Z [Term] id: FYPO:0004284 name: decreased oxanine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of oxanine DNA N-glycosylase activity is decreased." [PomBase:mah] synonym: "reduced oxanine DNA N-glycosylase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004283 ! abnormal oxanine DNA N-glycosylase activity created_by: midori creation_date: 2015-01-14T13:48:26Z [Term] id: FYPO:0004285 name: normal growth on mitomycin C def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mitomycin C." [PomBase:mah] synonym: "normal cell population growth in presence of mitomycin C" EXACT [PomBase:mah] synonym: "normal cell population growth on mitomycin C" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on mitomycin C" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-01-14T14:04:16Z [Term] id: FYPO:0004286 name: normal double-strand break repair via nonhomologous end joining def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is normal (i.e. indistinguishable from wild type). NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity." [GO:0006303, PomBase:mah] synonym: "normal double-strand break repair via nonhomologous end joining during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal double-strand break repair via nonhomologous end joining during vegetative growth" EXACT [PomBase:mah] synonym: "normal NHEJ" EXACT [GO:0006303] synonym: "normal nonhomologous end joining" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-01-14T14:06:23Z [Term] id: FYPO:0004287 name: decreased double-strand break repair via nonhomologous end joining def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is decreased. NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity." [GO:0006303, PomBase:mah] synonym: "decreased double-strand break repair via nonhomologous end joining during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased double-strand break repair via nonhomologous end joining during vegetative growth" EXACT [PomBase:mah] synonym: "decreased NHEJ" EXACT [GO:0006303] synonym: "decreased nonhomologous end joining" EXACT [PomBase:mah] synonym: "reduced double-strand break repair via nonhomologous end joining" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2015-01-14T14:07:13Z [Term] id: FYPO:0004288 name: decreased GT repeat stability def: "A cell phenotype in which the number of GT dinucleotide microsatellite repeats present in a sequence varies more than normal." [PMID:18062930, PomBase:al, PomBase:mah] synonym: "decreased GT dinucleotide repeat stability" EXACT [SO:0001862] synonym: "decreased GT microsatellite repeat stability" EXACT [PMID:18062930] synonym: "reduced GT repeat stability" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2015-01-14T14:09:12Z [Term] id: FYPO:0004289 name: decreased GU repeat RNA binding def: "A molecular function phenotype in which an interaction between a protein and GU repeat regions in an RNA is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "decreased protein-GU repeat RNA interaction" EXACT [PomBase:mah] synonym: "reduced GU repeat RNA binding" EXACT [PomBase:mah] is_a: FYPO:0002134 ! decreased protein-RNA interaction created_by: midori creation_date: 2015-01-14T14:25:05Z [Term] id: FYPO:0004290 name: decreased microsatellite DNA binding def: "A molecular function phenotype in which occurrence of DNA binding at microsatellite repeat regions by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased microsatellite repeat binding" EXACT [PomBase:mah] synonym: "reduced microsatellite DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2015-01-14T14:30:06Z [Term] id: FYPO:0004291 name: decreased GT microsatellite DNA binding def: "A molecular function phenotype in which occurrence of DNA binding at GT dinucleotide microsatellite repeat regions by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased GT dinucleotide microsatellite repeat binding" EXACT [PomBase:mah, SO:0001862] synonym: "decreased microsatellite (GT) DNA binding" EXACT [PomBase:al] synonym: "reduced GT microsatellite DNA binding" EXACT [PomBase:mah] is_a: FYPO:0004290 ! decreased microsatellite DNA binding created_by: midori creation_date: 2015-01-14T14:31:59Z [Term] id: FYPO:0004292 name: abnormal septum def: "A physical cellular phenotype in which the position or morphology of all or part of the septum is abnormal." [PomBase:mah] comment: Note that an abnormal septum organization process may, but does not necessarily, result in a physically abnormal septum. synonym: "abnormal septum physical object quality" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2015-01-14T14:54:41Z [Term] id: FYPO:0004293 name: mislocalized septum def: "A physical cellular phenotype in which a cell or hypha has a septum in an abnormal location. The normal location during yeast-form growth is at the midpoint of the long axis of the cell." [PomBase:mah] comment: Note that the location of the septum is determined by the location of the contractile ring, which in turn is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. synonym: "abnormal septum localization" RELATED [PomBase:mah] synonym: "abnormal septum location" EXACT [PomBase:mah] synonym: "abnormal septum position" EXACT [PomBase:mah] synonym: "abnormal septum positioning" RELATED [PomBase:mah] synonym: "asymmetric septum" RELATED [PomBase:mah] synonym: "asymmetrically located septum" RELATED [PomBase:mah] synonym: "mislocalised septum" EXACT [PomBase:mah] synonym: "misplaced septum" EXACT [PomBase:vw] is_a: FYPO:0004292 ! abnormal septum created_by: midori creation_date: 2015-01-14T14:55:00Z [Term] id: FYPO:0004294 name: mislocalized septum in stationary phase def: "A cell phenotype in which a cell has a septum in an abnormal location when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "abnormal septum localization in stationary phase" RELATED [PomBase:mah] synonym: "abnormal septum location in stationary phase" EXACT [PomBase:mah] synonym: "abnormal septum position in stationary phase" EXACT [PomBase:mah] synonym: "abnormal septum positioning in stationary phase" RELATED [PomBase:mah] synonym: "asymmetric septum in stationary phase" EXACT [PomBase:mah] synonym: "asymmetrically located septum in stationary phase" EXACT [PomBase:mah] synonym: "mislocalised septum in stationary phase" EXACT [PomBase:mah] synonym: "misplaced septum in stationary phase" EXACT [PomBase:vw] is_a: FYPO:0004293 ! mislocalized septum created_by: midori creation_date: 2015-01-14T15:03:00Z [Term] id: FYPO:0004295 name: multiseptate cell def: "A physical cellular phenotype characterized by the presence of more than one septum in a cell." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component is_a: FYPO:0004296 ! septated cell is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-01-14T15:06:08Z [Term] id: FYPO:0004296 name: septated cell def: "A physical cellular phenotype in which the cell contains one or more septa." [PomBase:mah] synonym: "septum present" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-01-14T15:10:27Z [Term] id: FYPO:0004297 name: multiseptate cell in stationary phase def: "A cell phenotype in which a cell contains more than one septum when the population in which the cell is found is in stationary phase." [PomBase:mah] is_a: FYPO:0004295 ! multiseptate cell created_by: midori creation_date: 2015-01-14T15:15:18Z [Term] id: FYPO:0004298 name: abnormal polynucleotide 5'-phosphatase activity def: "A molecular function phenotype in which the observed rate of polynucleotide 5'-phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-01-14T15:27:37Z [Term] id: FYPO:0004299 name: abolished polynucleotide 5'-phosphatase activity def: "A molecular function phenotype in which polynucleotide 5'-phosphatase activity is absent." [PomBase:mah] synonym: "polynucleotide 5'-phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004298 ! abnormal polynucleotide 5'-phosphatase activity created_by: midori creation_date: 2015-01-14T15:27:43Z [Term] id: FYPO:0004300 name: normal ATPase activity def: "A molecular function phenotype in which the observed rate of an ATPase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-01-14T15:34:37Z [Term] id: FYPO:0004301 name: normal mitotic sister chromatid separation def: "A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [GO:0051306, PomBase:mah] synonym: "normal mitotic chromosome separation" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid disjunction" RELATED [PomBase:mah] synonym: "normal mitotic sister chromatid separation during vegetative growth" EXACT [PomBase:mah] synonym: "normal sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-01-14T15:40:03Z [Term] id: FYPO:0004302 name: abnormal phosphatase activity def: "A molecular function phenotype in which the observed rate of a phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-01-14T15:47:31Z [Term] id: FYPO:0004303 name: abolished phosphatase activity def: "A molecular function phenotype in which a phosphatase activity is absent." [PomBase:mah] synonym: "phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004302 ! abnormal phosphatase activity created_by: midori creation_date: 2015-01-14T15:47:36Z [Term] id: FYPO:0004304 name: decreased phosphatase activity def: "A molecular function phenotype in which the observed rate of a phosphatase activity is decreased." [PomBase:mah] synonym: "reduced phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004302 ! abnormal phosphatase activity created_by: midori creation_date: 2015-01-14T15:47:44Z [Term] id: FYPO:0004305 name: abnormal CTD phosphatase activity def: "A molecular function phenotype in which the observed rate of CTD phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-01-14T15:49:49Z [Term] id: FYPO:0004306 name: decreased CTD phosphatase activity def: "A molecular function phenotype in which the observed rate of CTD phosphatase activity is decreased." [PomBase:mah] synonym: "reduced CTD phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004305 ! abnormal CTD phosphatase activity created_by: midori creation_date: 2015-01-14T15:50:09Z [Term] id: FYPO:0004307 name: long mitotic spindle during metaphase def: "A spindle phenotype in which the mitotic spindle is longer than normal during metaphase." [PMID:10398680, PomBase:mah] synonym: "elongated mitotic spindle during metaphase" EXACT [PomBase:mah] synonym: "increased mitotic spindle length during metaphase" EXACT [PomBase:vw] synonym: "long bipolar mitotic spindle during metaphase" EXACT [PomBase:vw] synonym: "long mitotic spindle during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "long mitotic spindles during metaphase" EXACT [PomBase:mah] synonym: "long spindle during metaphase of mitosis" EXACT [PomBase:mah] synonym: "long spindle during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0000733 ! long mitotic spindle created_by: midori creation_date: 2015-01-14T16:46:02Z [Term] id: FYPO:0004308 name: abnormal CENP-A containing chromatin organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which CENP-A-containing chromatin organization is abnormal." [GO:0061641, PMID:9230309, PomBase:mah, PomBase:vw] synonym: "abnormal CENP-A containing chromatin organisation" EXACT [PomBase:mah] synonym: "abnormal CENP-A containing chromatin organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal CENP-A containing chromatin organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin organization at centromere central core" RELATED [PomBase:vw] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2015-01-14T17:08:06Z [Term] id: FYPO:0004310 name: normal duration of mitotic M phase alt_id: FYPO:0005632 def: "A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of M phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal duration of mitosis" RELATED [PomBase:mah] synonym: "normal duration of mitosis during vegetative growth" RELATED [PomBase:mah] synonym: "normal duration of mitotic division" RELATED [PomBase:mah] synonym: "normal duration of mitotic nuclear division" RELATED [GO:0140014] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2015-01-19T11:37:06Z [Term] id: FYPO:0004311 name: abnormal protein localization to CENP-A containing chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to CENP-A containing chromatin" EXACT [PomBase:mah] synonym: "abnormal protein localization to CENP-A containing chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to CENP-A containing chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to centromeric core region chromatin" EXACT [GO:0061638] is_a: FYPO:0005306 ! abnormal protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2015-01-19T11:48:30Z [Term] id: FYPO:0004312 name: abolished protein localization to CENP-A containing chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to CENP-A containing chromatin" EXACT [PomBase:mah] synonym: "abolished protein localization to CENP-A containing chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to CENP-A containing chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to centromeric core region chromatin" EXACT [GO:0061638] synonym: "protein localization to CENP-A containing chromatin abolished" EXACT [PomBase:mah] is_a: FYPO:0003744 ! abolished protein localization to centromeric chromatin during vegetative growth is_a: FYPO:0004311 ! abnormal protein localization to CENP-A containing chromatin created_by: midori creation_date: 2015-01-19T11:49:05Z [Term] id: FYPO:0004313 name: decreased protein localization to CENP-A containing chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to CENP-A containing chromatin" EXACT [PomBase:mah] synonym: "decreased protein localization to CENP-A containing chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to CENP-A containing chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric core region chromatin" EXACT [GO:0061638] synonym: "reduced protein localization to CENP-A containing chromatin" EXACT [PomBase:mah] is_a: FYPO:0004311 ! abnormal protein localization to CENP-A containing chromatin is_a: FYPO:0006599 ! decreased protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2015-01-19T11:49:39Z [Term] id: FYPO:0004314 name: normal protein localization to CENP-A containing chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the CENP-A containing chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to CENP-A containing chromatin" EXACT [PomBase:mah] synonym: "normal protein localization to CENP-A containing chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to CENP-A containing chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to centromeric core region chromatin" EXACT [GO:0061638] is_a: FYPO:0005072 ! normal protein localization to centromeric chromatin created_by: midori creation_date: 2015-01-19T11:51:16Z [Term] id: FYPO:0004315 name: abnormal microtubule cytoskeleton during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of all or part of the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in a physically abnormal microtubule cytoskeleton. synonym: "abnormal microtubule cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal microtubule cytoskeleton physical object quality during vegetative growth" EXACT [PomBase:mah] synonym: "disorganized microtubule cytoskeleton during vegetative growth" RELATED [Pombase:vw] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002399 ! abnormal microtubule cytoskeleton relationship: output_of FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2015-01-19T12:11:31Z [Term] id: FYPO:0004316 name: abnormal post-anaphase array def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of all or part of the post-anaphase array of microtubules is abnormal." [PomBase:mah] comment: Note that an abnormal post-anaphase microtubule array organization process may, but does not necessarily, result in abnormal post-anaphase microtubule array structure. synonym: "abnormal post-anaphase array during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal post-anaphase array physical object quality during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal post-anaphase microtubule array during vegetative growth" EXACT [GO:1990295] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2015-01-19T12:17:46Z [Term] id: FYPO:0004317 name: abnormal post-anaphase array morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the post-anaphase array of microtubules is abnormal." [PomBase:mah] comment: Note that an abnormal post-anaphase microtubule array organization process may, but does not necessarily, result in abnormal post-anaphase microtubule array structure. synonym: "abnormal microtubule cytoskeleton morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal post-anaphase array morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal post-anaphase microtubule array morphology" EXACT [GO:1990295] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0004316 ! abnormal post-anaphase array created_by: midori creation_date: 2015-01-19T12:18:25Z [Term] id: FYPO:0004318 name: abolished mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic cell cycle spindle assembly checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic spindle assembly checkpoint delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [GO:0007094, PMID:11432827, PomBase:mah] synonym: "abolished mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "mitotic spindle assembly checkpoint abolished" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint created_by: midori creation_date: 2015-01-19T12:30:47Z [Term] id: FYPO:0004319 name: increased cyclin-dependent protein kinase activity def: "A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2015-01-21T11:46:31Z [Term] id: FYPO:0004320 name: altered DNA level def: "A cell phenotype in which the amount of DNA measured in a cell differs from normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal DNA content" EXACT [PomBase:mah] synonym: "abnormal DNA level" EXACT [PomBase:mah] synonym: "altered cellular DNA level" EXACT [PomBase:mah] synonym: "altered DNA content" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2015-01-21T13:48:16Z [Term] id: FYPO:0004321 name: altered DNA level during vegetative growth def: "A cell phenotype in which the amount of DNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal DNA content during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal DNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular DNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered DNA content during vegetative growth" EXACT [PomBase:mah] synonym: "altered DNA level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth is_a: FYPO:0004320 ! altered DNA level created_by: midori creation_date: 2015-01-21T13:48:25Z [Term] id: FYPO:0004322 name: decreased spatial extent of CENP-A containing chromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a smaller portion of the centromeric region of the chromosome than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions." [GO:0034080, PMID:18493607, PomBase:mah, PomBase:vw] synonym: "decreased extent of CENP-A containing nucleosome" RELATED [PomBase:vw] synonym: "decreased spatial extent of CenH3-containing nucleosome assembly at centromere" RELATED [GO:0034080] synonym: "decreased spatial extent of CENP-A containing nucleosome assembly" RELATED [] synonym: "decreased spatial extent of CENP-A containing nucleosome assembly at centromere" EXACT [GO:0034080] synonym: "decreased spatial extent of CENP-A containing nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spatial extent of CENP-A containing nucleosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spatial extent of CENP-A deposition" RELATED [GO:0034080] synonym: "decreased spatial extent of CENP-A loading" RELATED [GO:0034080] synonym: "decreased spatial extent of centromere-specific histone exchange" EXACT [GO:0034080] synonym: "decreased spatial extent of centromere-specific nucleosome assembly" EXACT [GO:0034080] synonym: "decreased spatial extent of centromeric DNA replication-independent nucleosome assembly" EXACT [GO:0034080] synonym: "decreased spatial extent of DNA replication-independent nucleosome assembly at centromere" EXACT [GO:0034080] synonym: "reduced spatial extent of CENP-A containing nucleosome assembly" EXACT [PomBase:mah] is_a: FYPO:0003409 ! abnormal CENP-A containing chromatin assembly created_by: midori creation_date: 2015-01-21T14:17:27Z [Term] id: FYPO:0004323 name: obsolete increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at centromere central core during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 5, 8, 12 and 16 of histone H4 at the centromere central core occurs to a greater extent than normal." [PMID:18493607, PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "increased histone H4 acetylation (K5, K8, K12 and K16) at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K5, H4-K8, H4-K12 and H4-K16 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K5/8/12/16 acetylation at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K5, H4K8, H4K12 and H4K16 acetylation at centromere central core during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0004324 consider: FYPO:0007312 consider: FYPO:0007313 consider: FYPO:0007314 created_by: midori creation_date: 2015-01-21T14:19:15Z [Term] id: FYPO:0004324 name: increased histone H4-K16 acetylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in at the centromere central core occurs to a greater extent than normal." [PMID:18493607, PomBase:mah] synonym: "increased histone H4-K16 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K16 acetylation at centromere central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007632 ! increased histone H4-K16 acetylation during vegetative growth created_by: midori creation_date: 2015-01-21T14:22:48Z [Term] id: FYPO:0004325 name: sensitive to 5-fluorouracil def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 5-fluorouracil. Cells stop growing (and may die) at a concentration of 5-fluorouracil that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 5-fluorouracil" EXACT [PomBase:mah] synonym: "sensitive to 5-fluorouracil during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 5-fluorouracil during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to 5-FU" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-01-21T14:40:59Z [Term] id: FYPO:0004326 name: increased duration of protein phosphorylation during cellular response to methylglyoxal def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to methylglyoxal. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein phosphorylation during cellular response to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein phosphorylation during cellular response to methylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein phosphorylation during cellular response to methylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0000548 ! increased duration of protein modification during vegetative growth created_by: midori creation_date: 2015-01-21T14:43:13Z [Term] id: FYPO:0004327 name: normal protein phosphorylation during cellular response to sorbitol def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to sorbitol." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to sorbitol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to sorbitol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-01-21T14:44:18Z [Term] id: FYPO:0004328 name: normal protein localization during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular protein localization is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein localization during mitosis" EXACT [PomBase:mah] synonym: "normal protein localisation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein localization during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2015-01-29T11:18:47Z [Term] id: FYPO:0004329 name: normal mitotic rDNA separation def: "A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type) in regions containing ribosomal DNA (rDNA). Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [GO:0051306, PMID:17032733, PomBase:mah] synonym: "normal mitotic chromosome separation at rDNA" EXACT [PomBase:mah] synonym: "normal mitotic rDNA separation during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic ribosomal DNA separation" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid separation at rDNA" EXACT [GO:0051306] synonym: "normal rDNA separation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004301 ! normal mitotic sister chromatid separation created_by: midori creation_date: 2015-01-29T11:23:10Z [Term] id: FYPO:0004330 name: normal mitotic telomeric DNA separation def: "A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type) at telomeres. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [GO:0051306, PMID:17032733, PomBase:mah] synonym: "normal mitotic chromosome separation at telomere" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid separation at telomere" EXACT [GO:0051306] synonym: "normal mitotic telomere disjunction" EXACT [PomBase:vw] synonym: "normal mitotic telomeric DNA separation during vegetative growth" EXACT [PomBase:mah] synonym: "normal telomere separation" EXACT [PomBase:mah] synonym: "normal telomeric DNA separation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004301 ! normal mitotic sister chromatid separation created_by: midori creation_date: 2015-01-29T11:25:47Z [Term] id: FYPO:0004331 name: normal chromatin silencing at centromere central core def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is normal (i.e. indistinguishable from wild type) at the centromere central core. Chromatin silencing is the observed effect of processes that repress transcription at the centromere central core, which is normally assembled into CENP-A-containing chromatin." [PomBase:mah, PomBase:vw] comment: Note that the centromere central core corresponds to SO:0001796. Chromatin silencing phenotypes at the centromere central core may reflect the assembly or maintenance of CENP-A-containing chromatin. See the GO cellular component term 'CENP-A containing chromatin' (GO:0061638), and the biological process term 'CENP-A containing chromatin organization' (GO:0061641). synonym: "normal centromere central core chromatin silencing" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromeric central core" EXACT [PomBase:mah] synonym: "normal negative regulation of transcription at centromere central core" RELATED [PomBase:mah] synonym: "normal transcriptional repression at centromere central core" RELATED [PomBase:mah] is_a: FYPO:0002335 ! normal chromatin silencing created_by: midori creation_date: 2015-01-29T11:31:51Z [Term] id: FYPO:0004332 name: delayed onset of protein degradation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation begins later than normal during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein breakdown during mitosis" EXACT [GO:0030163] synonym: "delayed onset of protein catabolic process during mitosis" EXACT [GO:0030163] synonym: "delayed onset of protein catabolism during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "delayed onset of protein degradation during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein degradation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein degradation during mitotic M phase" RELATED [PomBase:mah] synonym: "delayed onset of protein degradation during mitotic nuclear division" EXACT [GO:0140014] synonym: "delayed protein degradation during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth created_by: midori creation_date: 2015-01-29T12:03:37Z [Term] id: FYPO:0004333 name: increased protein phosphorylation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to hydrogen peroxide." [PMID:22139357, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-01-29T13:34:48Z [Term] id: FYPO:0004334 name: increased protein localization to nucleus during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to hydrogen peroxide." [PMID:22139357, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus during cellular response to hydrogen peroxide" EXACT [GO:0034504, PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to H2O2" EXACT [PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001130 ! increased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-01-29T13:39:28Z [Term] id: FYPO:0004335 name: abolished protein-protein interaction during cellular response to hydrogen peroxide def: "A molecular function phenotype in which the binding of one protein to another does not occur during a cellular response to hydrogen peroxide. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PMID:22139357, PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished protein binding cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein-protein interaction during cellular response to H2O2" EXACT [PomBase:mah] synonym: "protein-protein interaction abolished during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0003425 ! abolished protein-protein interaction during cellular response to rapamycin created_by: midori creation_date: 2015-01-29T13:42:03Z [Term] id: FYPO:0004336 name: abnormal protein localization to mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to mitochondrion" EXACT [PomBase:mah] synonym: "abnormal protein localization to mitochondria" EXACT [PomBase:mah] synonym: "abnormal protein localization to mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to mitochondrion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2015-01-29T13:59:03Z [Term] id: FYPO:0004337 name: abolished protein localization to mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to mitochondrion" EXACT [PomBase:mah] synonym: "abolished protein localization to mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from mitochondrion" RELATED [PomBase:mah] synonym: "protein localization to mitochondrion abolished" EXACT [PomBase:mah] synonym: "protein localization to mitochondrion abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0004336 ! abnormal protein localization to mitochondrion created_by: midori creation_date: 2015-01-29T14:05:52Z [Term] id: FYPO:0004338 name: abolished cell population growth on ethanol carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing ethanol as the carbon source." [PMID:22139357, PomBase:mah] comment: Use this term for a population of cells that does not grow with ethanol as the carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished ethanol utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished growth on ethanol carbon source" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth on ethanol carbon source" EXACT [PomBase:mah] synonym: "cell population growth on ethanol carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2015-01-29T14:07:32Z [Term] id: FYPO:0004339 name: decreased protein localization to nucleus during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to hydrogen peroxide" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to H2O2" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-01-29T14:09:16Z [Term] id: FYPO:0004340 name: abnormal mitochondrial fission def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, is abnormal." [GO:0000266, PomBase:mah] synonym: "abnormal mitochondrial division" EXACT [GO:0000266, PomBase:mah] synonym: "abnormal mitochondrial fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial fission during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitochondrial proliferation" RELATED [GO:0000266, PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2015-01-29T14:11:28Z [Term] id: FYPO:0004341 name: delayed onset of mitochondrial fission during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, begins later than normal during a cellular response to hydrogen peroxide." [PMID:22139357, PomBase:mah] synonym: "delayed mitochondrial fission during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "delayed onset of mitochondrial division" EXACT [GO:0000266, PomBase:mah] synonym: "delayed onset of mitochondrial fission during cellular response to H2O2" EXACT [PomBase:mah] synonym: "delayed onset of mitochondrial fission during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of mitochondrial fission during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitochondrial fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of mitochondrial fission during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitochondrial proliferation" RELATED [GO:0000266, PomBase:mah] is_a: FYPO:0004340 ! abnormal mitochondrial fission created_by: midori creation_date: 2015-01-29T14:13:00Z [Term] id: FYPO:0004342 name: increased LTR-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from long terminal repeat elements (LTRs) measured in a cell is higher than normal." [PMID:24095277, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased accumulation of LTR-derived RNAs" RELATED [PomBase:vw] synonym: "increased long terminal repeat-derived RNA level" EXACT [PomBase:mah] synonym: "increased LTR-derived RNA accumulation" RELATED [PomBase:mah] synonym: "increased LTR-derived RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased LTR-derived RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased LTR-derived transcript level" EXACT [PomBase:mah] is_a: FYPO:0003558 ! increased repeat element RNA level created_by: midori creation_date: 2015-01-29T14:47:36Z [Term] id: FYPO:0004343 name: increased wtf-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from wtf elements measured in a cell is higher than normal." [PMID:24095277, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased accumulation of wtf-derived RNAs" RELATED [PomBase:vw] synonym: "increased wtf element-derived RNA level" EXACT [PomBase:mah] synonym: "increased wtf-derived RNA accumulation" RELATED [PomBase:mah] synonym: "increased wtf-derived RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased wtf-derived RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased wtf-derived transcript level" EXACT [PomBase:mah] is_a: FYPO:0003558 ! increased repeat element RNA level created_by: midori creation_date: 2015-01-29T14:50:29Z [Term] id: FYPO:0004344 name: increased viability upon nitrogen starvation def: "A cell population phenotype in which a larger than normal proportion of cells in the population remains viable when cells the population are subject to nitrogen starvation." [PomBase:mah] synonym: "increased cell population viability upon nitrogen starvation" EXACT [PomBase:mah] synonym: "increased viability during nitrogen starvation" EXACT [PomBase:al] synonym: "increased viability upon nitrogen depletion" EXACT [PomBase:al] synonym: "increased viability upon nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2015-01-29T14:54:06Z [Term] id: FYPO:0004345 name: decreased protein localization to chromatin at long terminal repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at long terminal repeats is decreased." [PMID:25002536, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at long terminal repeat" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at long terminal repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at long terminal repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at LTR" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at long terminal repeat" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-01-29T14:58:45Z [Term] id: FYPO:0004346 name: decreased protein localization to chromatin at ncRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA genes is decreased." [PMID:25002536, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at ncRNA genes" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at ncRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at ncRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at non-coding RNA genes" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at ncRNA genes" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-01-29T15:00:04Z [Term] id: FYPO:0004347 name: increased histone H3-K9 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a greater extent than normal in regions containing protein-coding genes." [PomBase:mah] synonym: "increased histone H3-K9 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 acetylation at protein coding gene during vegetative growth" EXACT [GO:0043970, PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2015-01-29T15:02:24Z [Term] id: FYPO:0004348 name: normal growth on methylglyoxal def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methylglyoxal." [PomBase:mah] synonym: "normal cell population growth in presence of methylglyoxal" EXACT [PomBase:mah] synonym: "normal cell population growth on methylglyoxal" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to methylglyoxal" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on methylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-01-29T15:17:53Z [Term] id: FYPO:0004349 name: decreased RNA level during cellular response to methylglyoxal def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methylglyoxal is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to methylglyoxal" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to methylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to methylglyoxal" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to methylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-01-29T15:20:59Z [Term] id: FYPO:0004350 name: normal RNA level during cellular response to methylglyoxal def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methylglyoxal is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to methylglyoxal" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to methylglyoxal" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to methylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to methylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2015-01-29T15:23:34Z [Term] id: FYPO:0004351 name: increased protein localization to nucleus during cellular response to methylglyoxal def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to methylglyoxal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus during cellular response to methylglyoxal" EXACT [GO:0034504, PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to methylglyoxal during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001130 ! increased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-01-29T15:24:30Z [Term] id: FYPO:0004352 name: decreased protein localization to nucleus during cellular response to methylglyoxal def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to methylglyoxal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to methylglyoxal" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to methylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to methylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during cellular response to methylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-01-29T15:25:11Z [Term] id: FYPO:0004353 name: increased protein phosphorylation during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during S phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during mitotic S-phase" EXACT [PomBase:vw] synonym: "increased protein/peptide phosphorylation during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-01-29T15:32:00Z [Term] id: FYPO:0004354 name: increased protein phosphorylation during mitotic G1 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during mitotic G1-phase" EXACT [PomBase:vw] synonym: "increased protein/peptide phosphorylation during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-01-29T15:32:39Z [Term] id: FYPO:0004355 name: increased protein phosphorylation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during mitotic nuclear division" EXACT [GO:0140014] synonym: "increased protein/peptide phosphorylation during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-01-29T15:33:18Z [Term] id: FYPO:0004356 name: increased protein localization to nucleolus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleolus" EXACT [PomBase:mah] synonym: "increased protein localization to nucleolus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleolus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003687 ! abnormal protein localization to nucleolus created_by: midori creation_date: 2015-01-29T15:36:57Z [Term] id: FYPO:0004357 name: decreased protein phosphorylation during mitosis alt_id: FYPO:0002832 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic M-phase" RELATED [PomBase:vw] synonym: "decreased protein phosphorylation during mitotic nuclear division" EXACT [GO:0140014] synonym: "decreased protein/peptide phosphorylation during mitosis" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-01-29T15:40:46Z [Term] id: FYPO:0004358 name: increased protein phosphatase activity during mitosis def: "A molecular function phenotype in which the observed rate of a protein phosphatase activity is increased during mitosis." [PomBase:mah] synonym: "increased phosphoprotein phosphatase activity during mitosis" EXACT [GO:0004721, PomBase:mah] synonym: "increased protein phosphatase activity during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein phosphatase activity during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0001758 ! increased protein phosphatase activity created_by: midori creation_date: 2015-01-29T15:43:00Z [Term] id: FYPO:0004359 name: abolished mitotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic cell cycle DNA replication checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete." [GO:0033314, PMID:11988741, PomBase:mah] is_a: FYPO:0000173 ! abnormal mitotic cell cycle DNA replication checkpoint created_by: midori creation_date: 2015-01-29T15:48:14Z [Term] id: FYPO:0004360 name: decreased duration of mitotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype in which the duration of mitotic cell cycle arrest or delay due to regulation by the DNA replication checkpoint is shorter than normal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete." [PomBase:mah] synonym: "decreased duration of DNA replication checkpoint" BROAD [PomBase:mah] synonym: "decreased duration of mitotic cell cycle DNA replication checkpoint activation" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "reduced duration of mitotic cell cycle DNA replication checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000173 ! abnormal mitotic cell cycle DNA replication checkpoint created_by: midori creation_date: 2015-01-29T15:49:40Z [Term] id: FYPO:0004361 name: meiotic cell cycle entry and sporulation in haploid during nitrogen starvation def: "A cellular process phenotype in which haploid cells undergo meiotic nuclear division and attempt to sporulate when the cells are subject to nitrogen starvation. Haploid meiosis often results in the formation of a structure that resembles an azygotic ascus. Spores produced from a haploid cell have poor viability and appear to contain only 1/2C DNA on average." [DOI:10.1007/BF00332932, PomBase:mah] synonym: "haploid meiosis during nitrogen starvation" RELATED [PomBase:al] synonym: "haploid sporulation during nitrogen starvation" RELATED [PomBase:al] synonym: "meiosis in haploid during nitrogen starvation" RELATED [PomBase:mah] synonym: "meiotic nuclear division and sporulation in haploid during nitrogen starvation" NARROW [PomBase:mah] synonym: "sporulation in haploid during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0001886 ! meiotic cell cycle entry and sporulation in haploid created_by: midori creation_date: 2015-01-29T15:56:24Z [Term] id: FYPO:0004362 name: increased protein localization to old growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to an old growing cell tip is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to old growing cell tip" EXACT [GO:0035840, PomBase:mah] synonym: "increased protein localization to old growing cell end" EXACT [PomBase:mah] synonym: "increased protein localization to old growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to old growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2015-02-02T16:15:35Z [Term] id: FYPO:0004363 name: altered level of stress responsive gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "abnormal level of stress responsive gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of cellular response to stress responsive gene mRNA" EXACT [PomBase:al] synonym: "altered level of stress responsive gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered level of stress responsive gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of stress responsive gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "altered mRNA level of stress responsive genes during vegetative growth" EXACT [PomBase:al] synonym: "altered stress responsive gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2015-02-10T12:15:37Z [Term] id: FYPO:0004364 name: abnormal dioxygenase activity def: "A molecular function phenotype in which the observed rate of a dioxygenase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-02-10T12:26:02Z [Term] id: FYPO:0004365 name: abolished dioxygenase activity def: "A molecular function phenotype in which a dioxygenase activity is absent." [PomBase:mah] synonym: "dioxygenase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004364 ! abnormal dioxygenase activity created_by: midori creation_date: 2015-02-10T12:26:07Z [Term] id: FYPO:0004366 name: syntelic kinetochore attachment during mitosis def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic nuclear division results in the connection of both sister kinetochores to microtubules from the same spindle pole." [PMID:17426725] comment: Syntelic attachment activates the spindle assembly checkpoint, presumably due to lack of tension between the sister chromatids. If uncorrected, syntelic attachment will result in segregation of both sister chromatids to the same daughter cell, generating aneuploidy. synonym: "syntelic attachment of spindle microtubules to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "syntelic kinetochore attachment during mitotic M phase" RELATED [PomBase:mah] synonym: "syntelic kinetochore attachment during mitotic nuclear division" EXACT [GO:0140014] synonym: "syntelic kinetochore attachment during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004213 ! abnormal attachment of mitotic spindle microtubules to kinetochore created_by: midori creation_date: 2015-02-10T12:37:25Z [Term] id: FYPO:0004367 name: normal mitotic spindle assembly def: "A cellular process phenotype in which assembly of the mitotic spindle is normal (i.e. indistinguishable from wild type). Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle." [PomBase:mah] synonym: "normal mitotic spindle assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic spindle formation" EXACT [PomBase:mah] synonym: "normal spindle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spindle assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth relationship: has_output FYPO:0001399 ! normal mitotic spindle created_by: midori creation_date: 2015-02-10T13:22:16Z [Term] id: FYPO:0004368 name: normal growth on arsenic def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing an arsenic-containing substance." [PomBase:mah] synonym: "normal cell population growth in presence of arsenic" EXACT [PomBase:mah] synonym: "normal cell population growth on arsenic" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to arsenic" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on arsenic molecular entity" EXACT [CHEBI:22632] synonym: "normal growth on arsenic-containing substance" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on arsenic" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-10T13:48:12Z [Term] id: FYPO:0004369 name: decreased vacuolar phytochelatin level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of phytochelatin in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar phytochelatin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased vacuolar phytochelatin level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of phytochelatin in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar phytochelatin level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0002829 ! decreased cellular phytochelatin level created_by: midori creation_date: 2015-02-10T13:57:23Z [Term] id: FYPO:0004370 name: decreased cadmium ion import into vacuole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of cadmium ions into the vacuole occurs to a lower extent than normal." [GO:0036249, PomBase:mah] synonym: "decreased cadmium import into vacuole" EXACT [PomBase:al] synonym: "decreased cadmium ion import into vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cadmium ion import into vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cadmium ion import into vacuole" EXACT [PomBase:mah] is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2015-02-10T14:05:17Z [Term] id: FYPO:0004371 name: decreased duration of S-phase DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the S-phase DNA damage checkpoint is lower than in wild type." [PomBase:mah] synonym: "decreased duration of intra-S DNA damage checkpoint" EXACT [PomBase:mah] synonym: "decreased duration of mitotic S-phase DNA damage checkpoint" EXACT [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint activation" EXACT [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "premature S-phase DNA damage checkpoint deactivation" RELATED [PomBase:mah] synonym: "reduced duration of S-phase DNA damage checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal mitotic DNA damage checkpoint created_by: midori creation_date: 2015-02-10T14:07:50Z [Term] id: FYPO:0004372 name: decreased response to mitotic G2 DNA damage checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the mitotic G2 DNA damage checkpoint is decreased. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0072435, PomBase:mah] synonym: "decreased G2 DNA damage checkpoint during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic G2 DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "reduced response to mitotic G2 DNA damage checkpoint signaling" EXACT [PomBase:mah] is_a: FYPO:0004373 ! abnormal mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2015-02-10T14:20:52Z [Term] id: FYPO:0004373 name: abnormal mitotic G2 DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is abnormal. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0007095, PomBase:mah] synonym: "abnormal G2 DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle G2/M transition DNA damage checkpoint" EXACT [GO:0007095] synonym: "abnormal mitotic G2 DNA damage checkpoint activation" RELATED [PomBase:mah] synonym: "abnormal mitotic G2 DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal mitotic DNA damage checkpoint created_by: midori creation_date: 2015-02-10T14:21:16Z [Term] id: FYPO:0004374 name: abolished protein localization to cytoplasm during glucose starvation def: "A cell phenotype in which the localization of a protein to the cytoplasm is abolished when the cell is subject to glucose starvation." [PomBase:al, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cytoplasm during glucose starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasm during glucose depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasm during glucose deprivation" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasm during glucose limitation" RELATED [PomBase:mah] synonym: "protein localization to cytoplasm abolished during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0001375 ! abolished protein localization created_by: midori creation_date: 2015-02-12T11:09:56Z [Term] id: FYPO:0004375 name: sensitive to Ku-0063794 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Ku-0063794. Cells stop growing (and may die) at a concentration of Ku-0063794 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Ku-0063794" EXACT [PomBase:mah] synonym: "sensitive to KU 0063794" EXACT [PomBase:al] synonym: "sensitive to Ku-0063794 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to Ku-0063794 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-12T11:28:29Z [Term] id: FYPO:0004376 name: increased chromatin silencing at silent mating-type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is increased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "increased chromatin silencing at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "increased chromatin silencing at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000156 ! abnormal chromatin silencing at silent mating-type cassette created_by: midori creation_date: 2015-02-12T11:31:31Z [Term] id: FYPO:0004377 name: increased protein localization to heterochromatin at silent mating-type cassette def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to heterochromatin at silent mating-type cassette" EXACT [PomBase:mah] synonym: "increased protein localization to heterochromatin at mating-type region" EXACT [PomBase:mah] synonym: "increased protein localization to heterochromatin at mating-type region during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to heterochromatin at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to heterochromatin at silent mating-type cassette during vegetative growth" EXACT [PomBase:al] synonym: "increased protein localization to mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "increased protein localization to silent mating type heterochromatin" EXACT [PomBase:al] is_a: FYPO:0001131 ! abnormal protein localization to heterochromatin during vegetative growth created_by: midori creation_date: 2015-02-12T11:56:51Z [Term] id: FYPO:0004378 name: normal protein localization to heterochromatin at silent mating-type cassette def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to heterochromatin at silent mating-type cassette" EXACT [PomBase:mah] synonym: "normal protein localization to heterochromatin at mating-type region" EXACT [PomBase:mah] synonym: "normal protein localization to heterochromatin at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to heterochromatin at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "normal protein localization to silent mating type heterochromatin" EXACT [PomBase:al] synonym: "normal protein localization to silent mating-type cassette during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-02-12T11:59:22Z [Term] id: FYPO:0004380 name: increased protein localization to pericentric heterochromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin in pericentric regions is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to centric heterochromatin during vegetative growth" EXACT [GO:0005721] synonym: "increased protein localization to nuclear pericentric heterochromatin during vegetative growth" EXACT [GO:0005721] synonym: "increased protein localization to pericentric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002838 ! abnormal protein localization to chromosome during vegetative growth is_a: FYPO:0007648 ! abnormal protein localization to pericentric heterochromatin created_by: midori creation_date: 2015-02-12T12:09:55Z [Term] id: FYPO:0004381 name: merotelic kinetochore attachment during mitosis def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic nuclear division results in the connection of a single kinetochore to both spindle poles." [PMID:17426725, PMID:21306900, PomBase:mah] synonym: "merotelic attachment of spindle microtubules to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "merotelic kinetochore attachment during mitotic M phase" RELATED [PomBase:mah] synonym: "merotelic kinetochore attachment during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0002651 ! merotelic kinetochore attachment is_a: FYPO:0004213 ! abnormal attachment of mitotic spindle microtubules to kinetochore created_by: midori creation_date: 2015-02-12T13:14:50Z [Term] id: FYPO:0004382 name: meroterically attached lagging mitotic chromosomes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a single kinetochore becomes attached to both spindle poles, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation." [PMID:20935472, PomBase:mah] synonym: "abnormal mitotic sister chromatid segregation, with merotelic kinetochore attachment and lagging mitotic chromosomes" EXACT [PomBase:mah] synonym: "lagging mitotic chromosomes with merotelic kinetochore attachment" EXACT [PomBase:mah] synonym: "lagging mitotic sister chromatids, with merotelic kinetochore attachment" EXACT [PomBase:mah] synonym: "merotelic kinetochore attachment with lagging mitotic chromosomes" EXACT [PomBase:mah] synonym: "meroterically attached lagging mitotic chromosomes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "meroterically attached lagging mitotic chromosomes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0004213 ! abnormal attachment of mitotic spindle microtubules to kinetochore relationship: has_part FYPO:0000228 ! lagging mitotic chromosomes relationship: has_part FYPO:0004381 ! merotelic kinetochore attachment during mitosis created_by: midori creation_date: 2015-02-12T13:17:18Z [Term] id: FYPO:0004383 name: premature protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle begins earlier than normal." [PMID:20935472, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to mitotic spindle" EXACT [PomBase:mah] synonym: "precocious protein localization to mitotic spindle" RELATED [PATO:0000694, PMID:20935472] synonym: "premature protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "premature protein localization to mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature protein localization to spindle during mitosis" EXACT [PomBase:mah] synonym: "premature protein localization to spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2015-02-12T13:24:05Z [Term] id: FYPO:0004384 name: normal single-stranded DNA binding def: "A molecular function phenotype in which occurrence of single-stranded DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal ssDNA binding" EXACT [GO:0003697] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2015-02-12T16:23:46Z [Term] id: FYPO:0004385 name: decreased single-stranded DNA binding def: "A molecular function phenotype in which occurrence of single-stranded DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased ssDNA binding" EXACT [GO:0003697] synonym: "reduced single-stranded DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2015-02-12T16:25:06Z [Term] id: FYPO:0004386 name: abolished single-stranded DNA binding def: "A molecular function phenotype in which single-stranded DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished ssDNA binding" EXACT [GO:0003697] synonym: "single-stranded DNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2015-02-12T16:25:42Z [Term] id: FYPO:0004387 name: decreased positive regulation of DNA-directed DNA polymerase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity occurs to a lower extent than normal." [PMID:14766746, PomBase:mah] synonym: "decreased activation of DNA-directed DNA polymerase activity" NARROW [GO:1900264] synonym: "decreased positive regulation of DNA polymerase activity" BROAD [PomBase:mah] synonym: "decreased positive regulation of DNA-directed DNA polymerase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased positive regulation of DNA-directed DNA polymerase activity during vegetative growth" EXACT [PomBase:mah] synonym: "reduced positive regulation of DNA-directed DNA polymerase activity" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2015-02-12T16:28:05Z [Term] id: FYPO:0004388 name: increased level of pyrimidine salvage gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pyrimidine salvage RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Pyrimidine salvage RNAs are transcribed from genes whose products are involved in pyrimidine salvage." [PMID:23695302, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of pyrimidine salvage gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of pyrimidine salvage gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of pyrimidine salvage gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased pyrimidine salvage gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-02-12T16:35:02Z [Term] id: FYPO:0004389 name: increased level of amino acid catabolism gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid catabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid catabolism RNAs are transcribed from genes whose products are involved in amino acid catabolism." [PMID:23695302, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased amino acid catabolism gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of amino acid catabolism gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of amino acid catabolism gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of amino acid catabolism gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0002743 ! increased level of amino acid metabolism gene mRNA during vegetative growth created_by: midori creation_date: 2015-02-12T16:37:09Z [Term] id: FYPO:0004390 name: increased level of arginine catabolism gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more arginine catabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Arginine catabolism RNAs are transcribed from genes whose products are involved in arginine catabolism." [PMID:23695302, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased arginine catabolism gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of arginine catabolism gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of arginine catabolism gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of arginine catabolism gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0004389 ! increased level of amino acid catabolism gene mRNA during vegetative growth created_by: midori creation_date: 2015-02-12T16:38:01Z [Term] id: FYPO:0004391 name: abolished cell population growth on uracil nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing uracil as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with uracil as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on uracil nitrogen source" BROAD [PomBase:mah] synonym: "abolished uracil utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on uracil nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on uracil nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2015-02-12T16:39:43Z [Term] id: FYPO:0004392 name: abolished positive regulation of DNA-directed DNA polymerase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity does not occur." [PMID:14766746, PomBase:mah] synonym: "abolished activation of DNA-directed DNA polymerase activity" NARROW [GO:1900264] synonym: "abolished positive regulation of DNA-directed DNA polymerase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished positive regulation of DNA-directed DNA polymerase activity during vegetative growth" EXACT [PomBase:mah] synonym: "positive regulation of DNA-directed DNA polymerase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2015-02-12T16:49:04Z [Term] id: FYPO:0004393 name: lagging chromosomes during meiosis I def: "A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during meiosis I, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed." [PomBase:mah] synonym: "lagging chromosomes during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002091 ! lagging meiotic chromosomes is_a: FYPO:0004159 ! abnormal homologous chromosome segregation created_by: midori creation_date: 2015-02-17T12:22:32Z [Term] id: FYPO:0004394 name: lagging chromosomes during meiosis II def: "A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during meiosis II, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed." [PomBase:mah] synonym: "lagging chromosomes during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002091 ! lagging meiotic chromosomes is_a: FYPO:0005509 ! abnormal meiotic sister chromatid segregation created_by: midori creation_date: 2015-02-17T12:23:19Z [Term] id: FYPO:0004395 name: short bipolar mitotic spindle during metaphase def: "A spindle phenotype in which the mitotic spindle is shorter than normal during metaphase." [PomBase:mah] synonym: "decreased mitotic spindle length during metaphase" EXACT [PomBase:mah] synonym: "short mitotic spindle during metaphase" EXACT [PomBase:vw] synonym: "short mitotic spindle during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "short mitotic spindles during metaphase" EXACT [PomBase:mah] synonym: "short spindle during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0000732 ! short bipolar mitotic spindle created_by: midori creation_date: 2015-02-17T14:17:40Z [Term] id: FYPO:0004396 name: normal mitotic spindle elongation def: "A spindle phenotype in which mitotic spindle elongation, i.e. the process of lengthening the distance between poles of the mitotic spindle, is normal (i.e. indistinguishable from wild type)." [GO:0000022, PomBase:mah] synonym: "normal mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "normal spindle elongation during mitosis" EXACT [PomBase:mah] synonym: "normal spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-02-17T14:40:51Z [Term] id: FYPO:0004397 name: normal protein export from nucleus during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus is normal (i.e. indistinguishable from wild type). Export of all proteins or a specific protein may be assayed." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal nucleocytoplasmic protein export during vegetative growth" RELATED [PomBase:vw] synonym: "normal protein export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005397 ! normal intracellular protein transport during vegetative growth created_by: midori creation_date: 2015-02-17T14:47:14Z [Term] id: FYPO:0004398 name: resistance to phenylarsine oxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phenylarsine oxide than normal." [PomBase:mah] synonym: "resistance to phenylarsine oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to phenylarsine oxide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to phenylarsine oxide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-02-17T14:50:01Z [Term] id: FYPO:0004399 name: normal growth on KT5720 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the protein kinase inhibitor KT5720." [PomBase:mah] synonym: "normal cell population growth in presence of KT5720" EXACT [PomBase:mah] synonym: "normal cell population growth on KT5720" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to KT5720" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on KT5720" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:03:10Z [Term] id: FYPO:0004400 name: normal growth on KT5823 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the protein kinase inhibitor KT5823." [PomBase:mah] synonym: "normal cell population growth in presence of KT5823" EXACT [PomBase:mah] synonym: "normal cell population growth on KT5823" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to KT5823" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on KT5823" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:04:00Z [Term] id: FYPO:0004401 name: normal growth on KT5926 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the protein kinase inhibitor KT5926." [PomBase:mah] synonym: "normal cell population growth in presence of KT5926" EXACT [PomBase:mah] synonym: "normal cell population growth on KT5926" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to KT5926" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on KT5926" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:04:37Z [Term] id: FYPO:0004402 name: sensitive to JM216 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to JM216 (also called satraplatin). Cells stop growing (and may die) at a concentration of JM216 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to JM216" EXACT [PomBase:mah] synonym: "sensitive to JM216 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to JM216 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to satraplatin" EXACT [CHEBI:85609, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-17T15:19:23Z [Term] id: FYPO:0004403 name: resistance to JM216 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of JM216 (also called satraplatin) than normal." [PomBase:mah] synonym: "resistance to JM216 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to JM216 during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to satraplatin" EXACT [PomBase:mah] synonym: "resistant to JM216" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-02-17T15:31:56Z [Term] id: FYPO:0004404 name: normal growth on JM216 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing JM216 (also called satraplatin)." [PomBase:mah] synonym: "normal cell population growth in presence of JM216" EXACT [PomBase:mah] synonym: "normal cell population growth on JM216" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on satraplatin" EXACT [PomBase:mah] synonym: "normal cellular response to JM216" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on JM216" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:32:53Z [Term] id: FYPO:0004405 name: sensitive to JM335 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to JM335. Cells stop growing (and may die) at a concentration of JM335 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to JM335" EXACT [PomBase:mah] synonym: "sensitive to JM335 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to JM335 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-17T15:40:47Z [Term] id: FYPO:0004406 name: normal growth on JM335 def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing JM335." [PomBase:mah] synonym: "normal cell population growth in presence of JM335" EXACT [PomBase:mah] synonym: "normal cell population growth on JM335" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to JM335" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on JM335" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:42:00Z [Term] id: FYPO:0004407 name: sensitive to triplatin tetranitrate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to triplatin tetranitrate (also called BBR 3464). Cells stop growing (and may die) at a concentration of triplatin tetranitrate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to triplatin tetranitrate" EXACT [PomBase:mah] synonym: "sensitive to BBR 3464" EXACT [PomBase:mah] synonym: "sensitive to triplatin tetranitrate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to triplatin tetranitrate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-17T15:43:49Z [Term] id: FYPO:0004408 name: normal growth on triplatin tetranitrate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing triplatin tetranitrate (also called BBR 3464)." [PomBase:mah] synonym: "normal cell population growth in presence of triplatin tetranitrate" EXACT [PomBase:mah] synonym: "normal cell population growth on BBR 3464" EXACT [PomBase:mah] synonym: "normal cell population growth on triplatin tetranitrate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to triplatin tetranitrate" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on triplatin tetranitrate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:47:54Z [Term] id: FYPO:0004409 name: sensitive to tetraplatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tetraplatin. Cells stop growing (and may die) at a concentration of tetraplatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tetraplatin" EXACT [PomBase:mah] synonym: "sensitive to tetraplatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tetraplatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-17T15:51:03Z [Term] id: FYPO:0004410 name: normal growth on tetraplatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tetraplatin." [PomBase:mah] synonym: "normal cell population growth in presence of tetraplatin" EXACT [PomBase:mah] synonym: "normal cell population growth on tetraplatin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to tetraplatin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tetraplatin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:52:00Z [Term] id: FYPO:0004411 name: normal growth on oxaliplatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing oxaliplatin." [PomBase:mah] synonym: "normal cell population growth in presence of oxaliplatin" EXACT [PomBase:mah] synonym: "normal cell population growth on oxaliplatin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to oxaliplatin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on oxaliplatin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-02-17T15:52:29Z [Term] id: FYPO:0004412 name: abolished protein localization to mitotic spindle midzone during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase is the stage of mitosis in which chromosomes separate and migrate towards the poles of the spindle." [GO:0000090, GO:1902967, GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle midzone during anaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein absent from mitotic spindle midzone during anaphase" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle midzone abolished during anaphase" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle midzone abolished during anaphase" EXACT [PomBase:mah] synonym: "protein localization to spindle midzone abolished during anaphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003484 ! abolished protein localization to mitotic spindle midzone is_a: FYPO:0004754 ! abolished protein localization to mitotic spindle during mitosis created_by: midori creation_date: 2015-02-17T16:00:11Z [Term] id: FYPO:0004413 name: decreased phosphatase activity during cellular response to phosphate starvation def: "A molecular function phenotype in which the observed rate of a phosphatase activity is decreased during a cellular response to phosphate starvation." [PomBase:mah] synonym: "decreased phosphatase activity during phosphate starvation" EXACT [PomBase:al] synonym: "reduced phosphatase activity during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0004304 ! decreased phosphatase activity created_by: midori creation_date: 2015-02-17T16:15:43Z [Term] id: FYPO:0004414 name: increased phosphatase activity during cellular response to phosphate starvation def: "A molecular function phenotype in which the observed rate of a phosphatase activity is increased during a cellular response to phosphate starvation." [PomBase:mah] synonym: "increased phosphatase activity during phosphate starvation" EXACT [PomBase:al] is_a: FYPO:0004415 ! increased phosphatase activity created_by: midori creation_date: 2015-02-17T16:16:42Z [Term] id: FYPO:0004415 name: increased phosphatase activity def: "A molecular function phenotype in which the observed rate of a phosphatase activity is increased." [PomBase:mah] is_a: FYPO:0004302 ! abnormal phosphatase activity created_by: midori creation_date: 2015-02-17T16:17:01Z [Term] id: FYPO:0004416 name: decreased RNA level during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to phosphate starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to phosphate starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to phosphate depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to phosphate deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during phosphate starvation" EXACT [PomBase:al] synonym: "decreased transcript level during cellular response to phosphate starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0003195 ! altered RNA level during cellular response to phosphate starvation created_by: midori creation_date: 2015-02-17T16:29:12Z [Term] id: FYPO:0004417 name: normal RNA level during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to phosphate starvation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to phosphate starvation" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during phosphate starvation" EXACT [PomBase:al] synonym: "normal transcript level during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2015-02-17T16:31:11Z [Term] id: FYPO:0004418 name: cut cell with decreased poly(A)+ mRNA export from nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, and in which the export of polyadenylated mRNA from the nucleus is decreased. The daughter cells produced by septation are both inviable. Export of all polyadenylated mRNAs or a specific mRNA may be affected." [PMID:14511667, PomBase:mah, PomBase:vw] synonym: "cut cell with decreased poly(A)+ mRNA export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut cell with decreased poly(A)+ mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "cut cell with reduced poly(A)+ mRNA export from nucleus" EXACT [PomBase:mah] synonym: "cut with decreased poly(A)+ mRNA export from nucleus" EXACT [PomBase:mah] synonym: "decreased poly(A) mRNA export in cut" EXACT [PomBase:vw] synonym: "septation following abnormal mitotic chromosome segregation with decreased poly(A)+ mRNA export from nucleus" EXACT [PomBase:vw] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype relationship: has_part FYPO:0000229 ! cut relationship: has_part FYPO:0002522 ! decreased poly(A)+ mRNA export from nucleus created_by: midori creation_date: 2015-02-19T11:10:36Z [Term] id: FYPO:0004419 name: abolished protein localization to cytoplasm with increased protein localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is abolished, and the protein is instead present in the nucleus at a greater level than normal." [PMID:17362205, PomBase:al, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cytoplasm with increased protein localisation to nucleus" RELATED [PomBase:mah] synonym: "abolished protein localization to cytoplasm with increased protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cytoplasm with increased protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cytoplasm abolished with increased protein localization to nucleus" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2015-02-19T11:29:22Z [Term] id: FYPO:0004420 name: obsolete increased protein serine phosphorylation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-serine phosphorylation" EXACT [GO:0018105, PomBase:mah] synonym: "increased serine phosphorylation" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0002680 created_by: midori creation_date: 2015-02-19T11:38:00Z [Term] id: FYPO:0004421 name: obsolete increased protein serine phosphorylation during nitrogen starvation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-serine phosphorylation during nitrogen starvation" EXACT [GO:0018105, PomBase:mah] synonym: "increased protein serine phosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation during nitrogen deprivation" EXACT [PomBase:mah] synonym: "increased serine phosphorylation during nitrogen starvation" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0002681 created_by: midori creation_date: 2015-02-19T11:46:24Z [Term] id: FYPO:0004422 name: normal protein phosphorylation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002495 ! normal protein modification created_by: midori creation_date: 2015-02-19T11:48:19Z [Term] id: FYPO:0004423 name: normal protein threonine phosphorylation def: "A cellular process phenotype in which the phosphorylation of threonine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal peptidyl-threonine phosphorylation" EXACT [GO:0018107] is_a: FYPO:0004422 ! normal protein phosphorylation created_by: midori creation_date: 2015-02-19T11:49:56Z [Term] id: FYPO:0004424 name: obsolete increased protein threonine phosphorylation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of threonine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-threonine phosphorylation" EXACT [GO:0018107, PomBase:mah] synonym: "increased threonine phosphorylation" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0002680 created_by: midori creation_date: 2015-02-19T11:53:50Z [Term] id: FYPO:0004425 name: obsolete abolished protein threonine phosphorylation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of threonine residues in one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished peptidyl-threonine phosphorylation" EXACT [GO:0018107] synonym: "protein threonine phosphorylation abolished" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002678 created_by: midori creation_date: 2015-02-19T11:54:57Z [Term] id: FYPO:0004426 name: abnormal protein dephosphorylation def: "A cellular process phenotype in which the dephosphorylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2015-02-19T14:17:17Z [Term] id: FYPO:0004427 name: delayed onset of ribosomal S6 protein dephosphorylation during cellular response to nitrogen starvation def: "A cellular process phenotype in which the dephosphorylation of the ribosomal small subunit protein S6 begins later than normal when the cell is subject to nitrogen starvation." [PMID:24247430, PomBase:mah] synonym: "delayed onset of dephosphorylation of ribosomal S6 during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed onset of ribosomal S6 dephosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:al] synonym: "delayed ribosomal S6 protein dephosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0004426 ! abnormal protein dephosphorylation created_by: midori creation_date: 2015-02-19T14:21:45Z [Term] id: FYPO:0004428 name: increased rate of cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic cytokinesis is increased." [PomBase:mah] synonym: "increased rate of cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of mitotic cytokinesis" EXACT [GO:0000281, PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2015-02-19T14:29:27Z [Term] id: FYPO:0004429 name: normal rate of mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is normal (i.e. indistinguishable from wild type)." [PMID:19029336, PomBase:mah] synonym: "normal mitotic spindle elongation rate" EXACT [PomBase:mah] synonym: "normal rate of mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of spindle elongation during mitosis" EXACT [PomBase:mah] synonym: "normal rate of spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004396 ! normal mitotic spindle elongation created_by: midori creation_date: 2015-02-19T14:31:51Z [Term] id: FYPO:0004430 name: premature actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins earlier than normal, e.g. before the mitotic spindle has completely disassembled. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PMID:19029336, PomBase:mah] synonym: "advanced actomyosin contractile ring contraction" EXACT [PomBase:mah] synonym: "decreased dwell time before actomyosin contractile ring contraction" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring constriction" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "premature contractile ring contraction" EXACT [PomBase:vw] synonym: "premature cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "premature mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "premature mitotic contractile ring contraction" EXACT [PomBase:vw] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2015-02-19T14:35:04Z [Term] id: FYPO:0004431 name: sensitive to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone. Cells stop growing (and may die) at a concentration of 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone that allows wild type cells to grow." [PMID:18204818, PomBase:mah] synonym: "hypersensitive to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone" EXACT [PomBase:mah] synonym: "sensitive to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-19T14:41:03Z [Term] id: FYPO:0004432 name: sensitive to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone. Cells stop growing (and may die) at a concentration of 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone that allows wild type cells to grow." [PMID:18204818, PomBase:mah] synonym: "hypersensitive to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone" EXACT [PomBase:mah] synonym: "sensitive to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-19T14:42:56Z [Term] id: FYPO:0004433 name: sensitive to viridicatumtoxin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to viridicatumtoxin. Cells stop growing (and may die) at a concentration of viridicatumtoxin that allows wild type cells to grow." [PMID:18204818, PomBase:mah] synonym: "hypersensitive to viridicatumtoxin" EXACT [PomBase:mah] synonym: "sensitive to viridicatumtoxin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to viridicatumtoxin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-19T14:43:41Z [Term] id: FYPO:0004434 name: sensitive to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide. Cells stop growing (and may die) at a concentration of 4-amino-1-methyl-1H-imidazole-5-carboselenoamide that allows wild type cells to grow." [PMID:18204818, PomBase:mah] synonym: "hypersensitive to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide" EXACT [PomBase:mah] synonym: "sensitive to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-19T14:44:21Z [Term] id: FYPO:0004435 name: sensitive to tingenone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tingenone. Cells stop growing (and may die) at a concentration of tingenone that allows wild type cells to grow." [PMID:18204818, PomBase:mah] synonym: "hypersensitive to tingenone" EXACT [PomBase:mah] synonym: "sensitive to tingenone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tingenone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-02-19T14:44:58Z [Term] id: FYPO:0004436 name: increased error-prone translesion synthesis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which error-prone translesion synthesis occurs to a greater extent than normal. Error-prone translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication." [PMID:17515930, PomBase:mah] synonym: "increased DNA repair via error-prone translesion synthesis" EXACT [PomBase:al] synonym: "increased error-prone translesion synthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased error-prone translesion synthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003892 ! abnormal error-prone translesion synthesis created_by: midori creation_date: 2015-02-19T15:18:27Z [Term] id: FYPO:0004437 name: normal mitotic recombination frequency def: "A cellular process phenotype in which the frequency of occurrence of mitotic recombination is normal (i.e. indistinguishable from wild type)." [PMID:17515930, PomBase:mah] synonym: "normal mitotic recombination frequency during vegetative growth" EXACT [PomBase:mah] synonym: "normal occurrence of mitotic recombination" EXACT [PomBase:mah] synonym: "normal recombination frequency during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-02-19T15:24:04Z [Term] id: FYPO:0004438 name: long mitotic spindle during anaphase def: "A spindle phenotype in which the mitotic spindle is longer than normal during anaphase." [PMID:17352737, PomBase:mah] synonym: "elongated mitotic spindle during anaphase" EXACT [PomBase:mah] synonym: "increased mitotic spindle length during anaphase" EXACT [PomBase:vw] synonym: "long bipolar mitotic spindle during anaphase" EXACT [PomBase:vw] synonym: "long mitotic spindle during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "long mitotic spindles during anaphase" EXACT [PomBase:mah] synonym: "long spindle during anaphase of mitosis" EXACT [PomBase:mah] synonym: "long spindle during mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0000733 ! long mitotic spindle created_by: midori creation_date: 2015-02-19T15:28:58Z [Term] id: FYPO:0004439 name: long curved mitotic spindle during anaphase def: "A spindle phenotype in which the mitotic spindle is curved (i.e. follows a smooth bend rather than a straight line) and longer than normal during anaphase." [PMID:17352737, PomBase:mah] comment: In this phenotype, the spindle curves when it becomes longer than the long axis of the cell. synonym: "curved mitotic spindle with increased mitotic spindle length during anaphase" EXACT [PomBase:vw] synonym: "elongated curved mitotic spindle during anaphase" EXACT [PomBase:mah] synonym: "long curved bipolar mitotic spindle during anaphase" EXACT [PomBase:vw] synonym: "long curved mitotic spindle during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "long curved mitotic spindles during anaphase" EXACT [PomBase:mah] synonym: "long curved spindle during anaphase of mitosis" EXACT [PomBase:mah] synonym: "long curved spindle during mitotic anaphase" EXACT [PomBase:mah] synonym: "long mitotic spindle during anaphase, elongating beyond cell end resulting in long curved spindle" EXACT [PomBase:vw] is_a: FYPO:0000733 ! long mitotic spindle created_by: midori creation_date: 2015-02-19T15:34:08Z [Term] id: FYPO:0004440 name: normal cytosolic calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in the cytosol is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cytosolic calcium accumulation" RELATED [PomBase:mah] synonym: "normal cytosolic calcium ion level" EXACT [PomBase:mah] synonym: "normal cytosolic calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cytosolic calcium level during vegetative growth" EXACT [PomBase:mah] synonym: "normal levels of free cytosolic calcium" EXACT [PomBase:vw] is_a: FYPO:0001199 ! normal cellular calcium level is_a: FYPO:0001606 ! normal level of substance in cytosol created_by: midori creation_date: 2015-02-19T15:54:52Z [Term] id: FYPO:0004441 name: decreased cytosolic calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in the cytosol is lower than normal." [PomBase:mah] synonym: "decreased cytosolic calcium ion level" EXACT [PomBase:mah] synonym: "decreased cytosolic calcium ion level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cytosolic calcium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of calcium ions in cytosol" EXACT [PomBase:mah] synonym: "decreased levels of free cytosolic calcium" EXACT [PomBase:vw] synonym: "reduced cytosolic calcium level" EXACT [PomBase:mah] is_a: FYPO:0001197 ! decreased cellular calcium level is_a: FYPO:0001605 ! decreased level of substance in cytosol created_by: midori creation_date: 2015-02-19T15:56:25Z [Term] id: FYPO:0004442 name: decreased protein localization to prospore membrane def: "A cell phenotype in which the localization of a protein to the prospore membrane is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to prospore membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to forespore membrane" EXACT [PomBase:mah] synonym: "reduced protein localization to prospore membrane" EXACT [PomBase:mah] is_a: FYPO:0000677 ! abnormal protein localization to prospore membrane created_by: midori creation_date: 2015-02-19T16:00:51Z [Term] id: FYPO:0004443 name: decreased protein localization to prospore membrane during meiosis II def: "A cell phenotype in which the localization of a protein to the prospore membrane is decreased during the second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to prospore membrane during meiosis II" EXACT [PomBase:mah] synonym: "decreased protein localization to forespore membrane during meiosis II" EXACT [PomBase:mah] synonym: "decreased protein localization to prospore membrane during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein localization to prospore membrane during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0004442 ! decreased protein localization to prospore membrane created_by: midori creation_date: 2015-02-19T16:03:02Z [Term] id: FYPO:0004444 name: decreased protein localization to prospore membrane during meiosis II with protein mislocalized to plasma membrane def: "A cell phenotype in which the localization of a protein to the prospore membrane is decreased, and the protein is instead present in the plasma membrane, during the second meiotic nuclear division." [PMID:21832151, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to prospore membrane during meiosis II with protein mislocalized to plasma membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to forespore membrane during meiosis II with protein mislocalized to plasma membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to prospore membrane during second meiotic nuclear division with protein mislocalized to plasma membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to prospore membrane with protein mislocalized to plasma membrane during meiosis II" RELATED [PomBase:mah] synonym: "reduced protein localization to prospore membrane during meiosis II with protein mislocalized to plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0004442 ! decreased protein localization to prospore membrane created_by: midori creation_date: 2015-02-19T16:04:24Z [Term] id: FYPO:0004445 name: abolished protein localization to prospore membrane during meiosis II with protein mislocalized to plasma membrane def: "A cell phenotype in which the localization of a protein to the prospore membrane does not occur, and the protein is instead present in the plasma membrane, during the second meiotic nuclear division." [PMID:21832151, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to prospore membrane during meiosis II with protein mislocalised to plasma membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to forespore membrane during meiosis II with protein mislocalized to plasma membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to prospore membrane during second meiotic nuclear division with protein mislocalized to plasma membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to prospore membrane with protein mislocalized to plasma membrane during meiosis II" RELATED [PomBase:mah] synonym: "protein localization to prospore membrane abolished during meiosis II with protein mislocalized to plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0000677 ! abnormal protein localization to prospore membrane is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle created_by: midori creation_date: 2015-02-19T16:06:06Z [Term] id: FYPO:0004446 name: decreased endocytosis during meiotic cell cycle def: "A cellular process phenotype in which the occurrence of endocytosis is decreased during the meiotic cell cycle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "reduced actin-mediated endocytosis during meiotic cell cycle" EXACT [PomBase:vw] synonym: "reduced endocytosis during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003886 ! abnormal endocytosis is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle created_by: midori creation_date: 2015-02-19T16:08:40Z [Term] id: FYPO:0004447 name: protein mislocalized to prospore membrane def: "A cell phenotype in which a protein that is not normally found in the prospore membrane is observed there." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein mislocalised to prospore membrane" EXACT [PomBase:mah] synonym: "protein mislocalized to forespore membrane" EXACT [PomBase:mah] is_a: FYPO:0003452 ! mislocalized protein created_by: midori creation_date: 2015-02-19T16:13:35Z [Term] id: FYPO:0004448 name: mislocalized protein during meiotic cell cycle def: "A cell phenotype in which a protein is observed in a particular location where it is not normally found during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003452 ! mislocalized protein relationship: output_of FYPO:0005208 ! abolished protein localization during meiotic cell cycle created_by: midori creation_date: 2015-02-19T16:16:17Z [Term] id: FYPO:0004449 name: decreased protein phosphorylation during mitotic metaphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during metaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during metaphase of mitosis" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein/peptide phosphorylation during mitotic metaphase" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0004357 ! decreased protein phosphorylation during mitosis created_by: midori creation_date: 2015-02-24T10:42:13Z [Term] id: FYPO:0004450 name: normal protein phosphorylation during cellular response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to calcium ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to calcium" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-02-24T10:49:31Z [Term] id: FYPO:0004451 name: decreased protein level during cellular response to calcium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to calcium ions is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to calcium ion" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to calcium" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to calcium ion" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2015-02-24T10:50:52Z [Term] id: FYPO:0004452 name: decreased transcription from CDRE promoter in response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is decreased following a calcium ion stimulus." [PMID:25081204, PomBase:mah] synonym: "decreased transcription from CDRE promoter in response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from CDRE promoter in response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription from CDRE promoter in response to calcium ion" EXACT [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2015-02-24T10:53:45Z [Term] id: FYPO:0004453 name: decreased protein localization to nucleus during cellular response to calcium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to calcium ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to calcium ion" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during cellular response to calcium ion" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-02-24T11:46:02Z [Term] id: FYPO:0004454 name: resistance to calcium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of calcium ions than normal." [PomBase:mah] synonym: "resistance to calcium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to calcium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to calcium ion" EXACT [PomBase:mah] synonym: "resistance to calcium ions" EXACT [PomBase:mah] synonym: "resistant to calcium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-02-24T11:47:45Z [Term] id: FYPO:0004455 name: decreased protein localization to nucleus def: "A cell phenotype in which the localization of a protein to the nucleus is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus" EXACT [PomBase:mah] is_a: FYPO:0002956 ! abnormal protein localization to nucleus created_by: midori creation_date: 2015-02-24T12:07:32Z [Term] id: FYPO:0004456 name: increased protein localization to nucleus def: "A cell phenotype in which the localization of a protein to the nucleus is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus" EXACT [PomBase:mah] is_a: FYPO:0002956 ! abnormal protein localization to nucleus created_by: midori creation_date: 2015-02-24T12:07:58Z [Term] id: FYPO:0004457 name: decreased protein localization to nucleus during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the nucleus is decreased when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0004455 ! decreased protein localization to nucleus created_by: midori creation_date: 2015-02-24T12:10:47Z [Term] id: FYPO:0004458 name: increased level of DNA replication gene mRNA during nitrogen starvation def: "A cell phenotype in which the amount of one or more DNA replication RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) when the cell is subject to nitrogen starvation. DNA replication RNAs are transcribed from genes whose products are involved in DNA replication." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased DNA replication gene mRNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "increased level of DNA replication gene mRNA during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased level of DNA replication gene mRNA during nitrogen deprivation" EXACT [PomBase:mah] synonym: "increased level of DNA replication gene RNA during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased level of DNA replication gene transcripts nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0002020 ! increased RNA level during nitrogen starvation created_by: midori creation_date: 2015-02-24T13:19:36Z [Term] id: FYPO:0004459 name: increased level of translation gene mRNA during nitrogen starvation def: "A cell phenotype in which the amount of one or more translation RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) when the cell is subject to nitrogen starvation. Translation RNAs are transcribed from genes whose products are involved in translation." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of translation gene mRNA during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased level of translation gene mRNA during nitrogen deprivation" EXACT [PomBase:mah] synonym: "increased level of translation gene RNA during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased level of translation gene transcripts nitrogen starvation" EXACT [PomBase:vw] synonym: "increased translation gene mRNA accumulation during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0002020 ! increased RNA level during nitrogen starvation created_by: midori creation_date: 2015-02-24T13:34:12Z [Term] id: FYPO:0004460 name: decreased level of regulation of mitotic cell cycle gene mRNA during nitrogen starvation def: "A cell phenotype in which the amount of one or more regulation of mitotic cell cycle RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) when the cell is subject to nitrogen starvation. Regulation of mitotic cell cycle RNAs are transcribed from genes whose products are involved in regulation of the mitotic cell cycle." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of mitotic cell cycle regulation gene mRNA during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased level of regulation of mitotic cell cycle gene mRNA during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased level of regulation of mitotic cell cycle gene mRNA during nitrogen deprivation" EXACT [PomBase:mah] synonym: "decreased level of regulation of mitotic cell cycle gene RNA during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased level of regulation of mitotic cell cycle gene transcripts nitrogen starvation" EXACT [PomBase:vw] synonym: "decreased regulation of mitotic cell cycle gene mRNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "reduced level of regulation of mitotic cell cycle gene mRNA during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001152 ! decreased RNA level during nitrogen starvation created_by: midori creation_date: 2015-02-24T13:52:28Z [Term] id: FYPO:0004461 name: decreased level of regulation of sexual differentiation gene mRNA during nitrogen starvation def: "A cell phenotype in which the amount of one or more regulation of sexual differentiation RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) when the cell is subject to nitrogen starvation. Sexual differentiation RNAs are transcribed from genes whose products are involved in sexual differentiation, i.e. mating and sporulation." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of regulation of sexual differentiation gene mRNA during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased level of regulation of sexual differentiation gene mRNA during nitrogen deprivation" EXACT [PomBase:mah] synonym: "decreased level of regulation of sexual differentiation gene RNA during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased level of regulation of sexual differentiation gene transcripts nitrogen starvation" EXACT [PomBase:vw] synonym: "decreased level of sexual differentiation regulation gene mRNA during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased regulation of sexual differentiation gene mRNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "reduced level of regulation of sexual differentiation gene mRNA during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001152 ! decreased RNA level during nitrogen starvation created_by: midori creation_date: 2015-02-24T14:08:59Z [Term] id: FYPO:0004462 name: abolished protein localization to nucleus during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the nucleus is abolished when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during nitrogen deprivation" EXACT [PomBase:al] synonym: "nuclear exclusion during nitrogen starvation" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during nitrogen starvation" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0003450 ! abolished protein localization to nucleus created_by: midori creation_date: 2015-02-24T14:17:14Z [Term] id: FYPO:0004463 name: abolished protein localization to nucleus during glucose starvation def: "A cell phenotype in which the localization of a protein to the nucleus is abolished when the cell is subject to glucose starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abolished protein localisation to nucleus during glucose starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during glucose depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during glucose deprivation" EXACT [PomBase:al] synonym: "abolished protein localization to nucleus during glucose limitation" RELATED [PomBase:mah] synonym: "nuclear exclusion during glucose starvation" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during glucose starvation" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0003450 ! abolished protein localization to nucleus created_by: midori creation_date: 2015-02-24T14:19:19Z [Term] id: FYPO:0004464 name: decreased protein phosphorylation during cellular response to camptothecin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to camptothecin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to camptothecin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to CPT" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to camptothecin" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-02-24T14:31:35Z [Term] id: FYPO:0004465 name: normal protein phosphorylation during cellular response to camptothecin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to camptothecin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to camptothecin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to CPT" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-02-24T14:32:51Z [Term] id: FYPO:0004466 name: increased number of Rad52 foci during cellular response to camptothecin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to camptothecin." [PMID:22064477, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during cellular response to camptothecin" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to camptothecin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to CPT" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2015-02-24T14:33:53Z [Term] id: FYPO:0004467 name: normal protein localization to cell tip during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell tip during cellular response to salt stress" EXACT [PomBase:mah] synonym: "normal protein localization to cell end during cellular response to salt stress" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cell tip during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001587 ! normal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2015-02-24T15:38:17Z [Term] id: FYPO:0004468 name: decreased protein localization to cell tip during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell tip during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased protein localization to cell end during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased protein localization to cell tip during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell tip during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cell tip during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001586 ! decreased protein localization to cell tip during vegetative growth created_by: midori creation_date: 2015-02-24T15:41:04Z [Term] id: FYPO:0004469 name: normal phosphatase activity def: "A molecular function phenotype in which the observed rate of a phosphatase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-02-26T11:21:01Z [Term] id: FYPO:0004470 name: decreased protein localization to actomyosin contractile ring during mitotic anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased during anaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actomyosin contractile ring during mitotic anaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring during anaphase of mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring involved in mitotic cytokinesis during mitotic anaphase" EXACT [GO:1904498] synonym: "decreased protein localization to cytokinetic contractile ring during mitotic anaphase" EXACT [PomBase:vw] synonym: "decreased protein localization to mitotic contractile ring during mitotic anaphase" EXACT [PomBase:vw] synonym: "decreased protein recruitment to actomyosin contractile ring during mitotic anaphase" RELATED [PomBase:vw] synonym: "reduced protein localization to actomyosin contractile ring during mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0005467 ! decreased protein localization to actomyosin contractile ring during mitosis created_by: midori creation_date: 2015-02-26T11:22:18Z [Term] id: FYPO:0004471 name: protein mislocalized to nucleolus during mitotic telophase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleolus is observed there during telophase of mitosis." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleolus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleolus during mitotic telophase" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleolus during mitotic telophase" EXACT [PomBase:mah] synonym: "protein mislocalised to nucleolus during telophase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleolus during mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleolus during telophase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2015-02-26T11:25:05Z [Term] id: FYPO:0004472 name: abolished protein localization to cytoplasm with protein mislocalized to nucleolus during cellular response to latrunculin B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is abolished, and the protein is instead present in the nucleolus, during a cellular response to latrunculin B." [PMID:18951025, PomBase:al, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cytoplasm with protein mislocalised to nucleolus during cellular response to latrunculin B" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasm with protein mislocalized to nucleolus during cellular response to LatB" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasm with protein mislocalized to nucleolus during cellular response to latrunculin B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cytoplasm with protein mislocalized to nucleolus during cellular response to latrunculin B during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cytoplasm abolished with protein mislocalized to nucleolus during cellular response to latrunculin B" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2015-02-26T11:28:29Z [Term] id: FYPO:0004473 name: inviable after spore germination, without cell division, cell cycle arrest with unreplicated DNA def: "A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest with unreplicated DNA, and eventually dies." [PMID:9356477, PomBase:mah] synonym: "inviable following spore germination, without cell division, cell cycle arrest with unreplicated DNA" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, cell cycle arrest with unreplicated DNA" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, cell cycle arrest with unreplicated DNA" EXACT [PomBase:mah] is_a: FYPO:0001430 ! abnormal mitotic cell cycle arrest with unreplicated DNA is_a: FYPO:0001924 ! inviable after spore germination, without cell division, cell cycle arrest created_by: midori creation_date: 2015-02-26T11:41:02Z [Term] id: FYPO:0004474 name: normal mitotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype in which the mitotic cell cycle DNA replication checkpoint is normal (i.e. indistinguishable from wild type). The mitotic DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete." [PomBase:mah] synonym: "normal DNA replication checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal DNA replication checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic DNA replication checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0001703 ! normal mitotic cell cycle checkpoint created_by: midori creation_date: 2015-02-26T11:44:01Z [Term] id: FYPO:0004475 name: decreased mitotic DNA replication initiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication is decreased. Initiation may be affected at one or more origins." [PMID:22970243, PomBase:mah] synonym: "decreased DNA replication initiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitotic DNA replication initiation" EXACT [PomBase:mah] is_a: FYPO:0001344 ! abnormal mitotic DNA replication initiation created_by: midori creation_date: 2015-02-26T14:29:51Z [Term] id: FYPO:0004476 name: decreased protein phosphorylation during cellular response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to calcium ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to calcium" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to calcium ion" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-02-26T14:48:35Z [Term] id: FYPO:0004477 name: decreased RNA level during cellular response to calcium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to calcium ions is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to calcium ion" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to calcium" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to calcium ion" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to calcium ion" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-02-26T14:50:10Z [Term] id: FYPO:0004478 name: protein mislocalized to mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the mitochondrion is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the mitochondrion in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to mitochondrion" EXACT [PomBase:vw] synonym: "protein mislocalised to mitochondrion" EXACT [PomBase:mah] synonym: "protein mislocalised to mitochondrion during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to mitochondrion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2015-02-26T15:24:49Z [Term] id: FYPO:0004479 name: decreased transcription from CDRE promoter in response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is decreased during a cellular response to salt stress." [PMID:16928959, PomBase:mah] synonym: "decreased transcription from CDRE promoter during cellular response to salt stress" EXACT [PomBase:mah] synonym: "decreased transcription from CDRE promoter in response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from CDRE promoter in response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription from CDRE promoter in response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2015-03-09T16:00:10Z [Term] id: FYPO:0004480 name: decreased transcription from CDRE promoter in response to micafungin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is decreased during a cellular response to micafungin." [PMID:16928959, PomBase:mah] synonym: "decreased transcription from CDRE promoter during cellular response to micafungin" EXACT [PomBase:mah] synonym: "decreased transcription from CDRE promoter in response to micafungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from CDRE promoter in response to micafungin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription from CDRE promoter in response to micafungin" EXACT [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2015-03-09T16:01:31Z [Term] id: FYPO:0004481 name: abolished cell population growth at high temperature def: "A vegetative cell population growth phenotype in which a cell population does not grow at high temperatures." [PomBase:mah] comment: For fission yeast, high temperature usually corresponds to above 32 degrees Celsius. Use this term for a population of cells that does not grow at high temperature, but does grow at a lower temperature (a cell population that does not grow at any temperature would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished cell population growth at high temperature during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished growth at high temperature" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth at high temperature" EXACT [PomBase:mah] synonym: "cell population growth at high temperature abolished" EXACT [PomBase:mah] synonym: "heat sensitive" RELATED [PomBase:mah] synonym: "hypersensitive to high temperature" RELATED [PomBase:mah] synonym: "sensitive to heat" RELATED [PomBase:mah] synonym: "sensitive to high temperature" RELATED [PomBase:mah] synonym: "sensitive to high temperature during vegetative growth" RELATED [PomBase:mah] synonym: "temperature sensitive" RELATED [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2015-03-09T16:35:54Z [Term] id: FYPO:0004482 name: abnormal vacuole fusion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is abnormal." [GO:0042144, PomBase:mah] synonym: "abnormal homotypic vacuole fusion during vegetative growth" EXACT [GO:0042144] synonym: "abnormal vacuole fusion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal vacuole fusion, non-autophagic, during vegetative growth" EXACT [GO:0042144] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0006057 ! abnormal vacuole fusion created_by: midori creation_date: 2015-03-10T09:33:48Z [Term] id: FYPO:0004483 name: abnormal vacuole fusion during cellular hypotonic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion is abnormal during a cellular response to a hypotonic environment." [PomBase:mah] synonym: "abnormal homotypic vacuole fusion during cellular hypotonic response" EXACT [GO:0042144] synonym: "abnormal vacuole fusion during cellular hypotonic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal vacuole fusion during cellular hypotonic response during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vacuole fusion during hypotonic stress" EXACT [PomBase:al] synonym: "abnormal vacuole fusion, non-autophagic, during cellular hypotonic response" EXACT [GO:0042144] is_a: FYPO:0004482 ! abnormal vacuole fusion during vegetative growth created_by: midori creation_date: 2015-03-10T09:33:54Z [Term] id: FYPO:0004484 name: abolished protein localization to prospore membrane def: "A cell phenotype in which the localization of a protein to the prospore membrane is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to prospore membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to forespore membrane" EXACT [PomBase:mah] synonym: "protein localization to prospore membrane abolished" EXACT [PomBase:mah] is_a: FYPO:0000677 ! abnormal protein localization to prospore membrane created_by: midori creation_date: 2015-03-10T09:36:38Z [Term] id: FYPO:0004485 name: abnormal protein deacetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deacetylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein deacetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2015-03-10T09:55:57Z [Term] id: FYPO:0004486 name: abolished protein deacetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deacetylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein deacetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein deacetylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein deacetylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0004485 ! abnormal protein deacetylation during vegetative growth created_by: midori creation_date: 2015-03-10T09:56:05Z [Term] id: FYPO:0004487 name: increased protein acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002392 ! abnormal protein acetylation during vegetative growth created_by: midori creation_date: 2015-03-10T09:56:30Z [Term] id: FYPO:0004488 name: abolished protein lysine methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of one or more lysine residues in specific proteins, or at specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished peptidyl-lysine methylation during vegetative growth" EXACT [GO:0018022] synonym: "abolished protein acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein lysine methylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein lysine methylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002392 ! abnormal protein acetylation during vegetative growth created_by: midori creation_date: 2015-03-10T09:59:28Z [Term] id: FYPO:0004489 name: increased level of amino acid biosynthesis gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid biosynthesis RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid biosynthesis RNAs are transcribed from genes whose products are involved in amino acid biosynthetic processes." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased amino acid biosynthesis gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of amino acid biosynthesis gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of amino acid biosynthesis gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of amino acid biosynthesis gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0002743 ! increased level of amino acid metabolism gene mRNA during vegetative growth created_by: midori creation_date: 2015-03-10T10:33:21Z [Term] id: FYPO:0004490 name: increased level of transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Transport RNAs are transcribed from genes whose products are involved in one or more transport processes." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of transport gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-03-10T10:35:08Z [Term] id: FYPO:0004491 name: decreased nucleosome occupancy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at one or more specific sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:17446861, PomBase:mah] synonym: "decreased nucleosome occupancy during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy during vegetative growth" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy" EXACT [PomBase:mah] is_a: FYPO:0000853 ! abnormal nucleosome positioning created_by: midori creation_date: 2015-03-10T10:36:57Z [Term] id: FYPO:0004492 name: abnormal RNA 5'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 5' end of an RNA molecule is abnormal." [GO:0000967, PomBase:mah] synonym: "abnormal RNA 5'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RNA 5'-end processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2015-03-10T10:56:33Z [Term] id: FYPO:0004493 name: inviable after spore germination, single cell division, small cell def: "A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division to produce daughter cells that are smaller than normal, which then die." [PMID:8367300, PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, single cell division, decreased cell size" EXACT [PomBase:mah] synonym: "inviable after spore germination, single cell division, reduced cell size" EXACT [PomBase:mah] synonym: "inviable following spore germination, single cell division, small cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division, small cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division, small cell" EXACT [PomBase:mah] is_a: FYPO:0000645 ! small vegetative cell is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002280 ! inviable after spore germination, single cell division relationship: has_part FYPO:0000645 ! small vegetative cell created_by: midori creation_date: 2015-03-10T11:24:28Z [Term] id: FYPO:0004494 name: inviable branched, swollen, elongated vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, septated, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:jh, PomBase:mah] synonym: "inviable branched, elongated, swollen vegetative cell" EXACT [PomBase:vw] synonym: "inviable branched, swollen, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, swollen, elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; branched, swollen, elongated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0001512 ! branched, elongated cell is_a: FYPO:0002251 ! inviable swollen elongated vegetative cell is_a: FYPO:0006794 ! inviable branched, swollen vegetative cell created_by: midori creation_date: 2015-03-11T16:01:12Z [Term] id: FYPO:0004495 name: inviable branched, swollen, elongated, multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, has more than one septum, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:jh, PomBase:mah] synonym: "inviable branched, elongated, swollen, multiseptate vegetative cell" EXACT [PomBase:vw] synonym: "inviable branched, swollen, elongated, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, swollen, elongated, multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; branched, swollen, elongated, multiseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0003413 ! inviable branched, elongated, multiseptate vegetative cell is_a: FYPO:0004494 ! inviable branched, swollen, elongated vegetative cell is_a: FYPO:0006946 ! inviable swollen elongated multiseptate vegetative cell created_by: midori creation_date: 2015-03-11T16:04:12Z [Term] id: FYPO:0004496 name: small multiseptate cell during stationary phase def: "A cell morphology phenotype in which a cell is smaller than normal and contains more than one septum, when the cell is in a culture in stationary phase." [PMID:8292390, PomBase:mah] is_a: FYPO:0000023 ! small cell is_a: FYPO:0004295 ! multiseptate cell created_by: midori creation_date: 2015-03-11T16:31:01Z [Term] id: FYPO:0004497 name: small binucleate cell during stationary phase def: "A cell morphology phenotype in which a cell is smaller than normal and contains two nuclei, when the cell is in a culture in stationary phase." [PMID:8292390, PomBase:mah] synonym: "binucleate cell with decreased cell size during stationary phase" EXACT [PomBase:mah] synonym: "binucleate cell with reduced cell size during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000023 ! small cell is_a: FYPO:0003341 ! multinucleate created_by: midori creation_date: 2015-03-11T16:33:41Z [Term] id: FYPO:0004498 name: normal positive regulation of DNA-directed DNA polymerase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal positive regulation of DNA-directed DNA polymerase activity during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal positive regulation of DNA-directed DNA polymerase activity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0004920 ! normal regulation of catalytic activity created_by: midori creation_date: 2015-03-12T16:03:38Z [Term] id: FYPO:0004499 name: abnormal DNA polymerase processivity factor activity def: "A molecular function phenotype in which the rate or occurrence of DNA polymerase processivity factor activity is abnormal." [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2015-03-12T16:06:53Z [Term] id: FYPO:0004500 name: decreased DNA polymerase processivity factor activity def: "A molecular function phenotype in which the rate or occurrence of DNA polymerase processivity factor activity is decreased." [PomBase:mah] synonym: "reduced DNA polymerase processivity factor activity" EXACT [PomBase:mah] is_a: FYPO:0004499 ! abnormal DNA polymerase processivity factor activity created_by: midori creation_date: 2015-03-12T16:06:58Z [Term] id: FYPO:0004501 name: normal DNA polymerase processivity factor activity def: "A molecular function phenotype in which the rate and occurrence of DNA polymerase processivity factor activity are normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2015-03-12T16:11:26Z [Term] id: FYPO:0004502 name: normal positive regulation of ATPase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of an ATPase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal positive regulation of ATPase activity during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal positive regulation of ATPase activity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0004920 ! normal regulation of catalytic activity created_by: midori creation_date: 2015-03-12T16:12:30Z [Term] id: FYPO:0004503 name: increased cellular HMW ubiquitin conjugate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polyubiquitin conjugation is greater than normal." [PMID:16149916, PMID:8247131, PomBase:mah] synonym: "accumulation of high molecular mass ubiquitin conjugates" EXACT [PomBase:vw] synonym: "accumulation of high molecular weight ubiquitin conjugates" EXACT [PomBase:vw] synonym: "accumulation of HMW ubiquitin conjugates" EXACT [PomBase:vw] synonym: "increased cellular high molecular mass ubiquitin conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular high molecular weight ubiquitin conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular HMW ubiquitin conjugate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular HMW ubiquitin conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased HMW ubiquitin conjugate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2015-03-12T16:26:44Z [Term] id: FYPO:0004504 name: normal proteasome localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which proteasome localization is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal proteasome localisation" EXACT [PomBase:mah] synonym: "normal proteasome localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal proteasome localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal proteasome location" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-03-16T11:53:35Z [Term] id: FYPO:0004505 name: abnormal nucleolar chromatin organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar chromatin organization is abnormal." [GO:1990700, PMID:18362178, PomBase:mah] synonym: "abnormal chromatin organization at nucleolus" RELATED [PomBase:mah] synonym: "abnormal nucleolar chromatin organisation" EXACT [PomBase:mah] synonym: "abnormal nucleolar chromatin organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleolar chromatin organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2015-03-16T13:48:33Z [Term] id: FYPO:0004506 name: abnormal nucleolar chromatin organization resulting in peripheral chromatin distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar chromatin organization is abnormal, such that nucleolar chromatin is distributed in a ring-shaped structure around the nuclear periphery rather than in a crescent-shaped structure on one side of the nucleus." [GO:1990700, PMID:18362178, PomBase:mah] synonym: "abnormal chromatin organization at nucleolus resulting in peripheral chromatin distribution" RELATED [PomBase:mah] synonym: "abnormal chromosome morphology, hollow bowl phenotype" RELATED [PMID:2537310] synonym: "abnormal chromosome morphology, ring phenotype" RELATED [PMID:2537310] synonym: "abnormal nucleolar chromatin organisation resulting in peripheral chromatin distribution" EXACT [PomBase:mah] synonym: "abnormal nucleolar chromatin organization resulting in peripheral chromatin distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleolar chromatin organization resulting in peripheral chromatin distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleolar chromatin organization resulting in ring-shaped chromatin distribution" EXACT [PomBase:vw] synonym: "nucleolar chromatin abnormally dispersed around nuclear periphery" RELATED [PomBase:vw] synonym: "ring-shaped nuclear chromatin distribution" EXACT [PomBase:mah] synonym: "ring-shaped nuclear DNA" RELATED [PMID:17538026] is_a: FYPO:0004505 ! abnormal nucleolar chromatin organization is_a: FYPO:0005350 ! abnormal chromatin organization resulting in peripheral chromatin distribution created_by: midori creation_date: 2016-04-11T13:43:49Z [Term] id: FYPO:0004507 name: abolished centromeric DNA separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation does not occur at the centromeric regions. The remainder of the sister chromatids may or may not separate." [PMID:18362178, PomBase:mah] synonym: "abolished centromeric DNA separation during mitosis" EXACT [PomBase:mah] synonym: "abolished centromeric DNA separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished centromeric DNA separation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished DNA separation at centromere" EXACT [PomBase:mah] synonym: "abolished mitotic centromeric DNA separation" EXACT [PomBase:vw] synonym: "abolished mitotic sister chromatid separation at centromere" EXACT [PomBase:mah] synonym: "abolished segregation of centromeric DNA" RELATED [PomBase:mah] synonym: "abolished sister kinetochore separation" RELATED [PomBase:vw] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2015-03-16T14:15:54Z [Term] id: FYPO:0004508 name: abolished rDNA separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation does not occur at the rDNA repeat regions. The remainder of the sister chromatids may or may not separate." [PomBase:mah] synonym: "abolished mitotic sister chromatid separation at rDNA" EXACT [PomBase:mah] synonym: "abolished rDNA separation during mitosis" EXACT [PomBase:mah] synonym: "abolished rDNA separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished rDNA separation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished ribosomal DNA separation" EXACT [PomBase:mah] synonym: "abolished segregation of nucleolar rDNA" RELATED [PomBase:mah] is_a: FYPO:0000671 ! abnormal rDNA separation created_by: midori creation_date: 2015-03-16T14:23:50Z [Term] id: FYPO:0004510 name: abnormal spindle assembly during meiosis II def: "A cellular process phenotype in which assembly of the meiotic spindle is abnormal during the second meiotic nuclear division." [PomBase:mah] synonym: "abnormal meiosis II spindle assembly" EXACT [PomBase:mah] synonym: "abnormal meiosis II spindle formation" EXACT [PomBase:vw] synonym: "abnormal meiotic spindle assembly during meiosis II" EXACT [PomBase:mah] synonym: "abnormal spindle assembly at meiosis II" EXACT [PomBase:vw] synonym: "abnormal spindle assembly during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal spindle assembly involved in meiosis II" EXACT [PomBase:mah] is_a: FYPO:0000737 ! abnormal meiotic spindle assembly created_by: midori creation_date: 2015-03-16T14:52:17Z [Term] id: FYPO:0004511 name: long curved interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal and are curved, i.e. follow a smooth bend rather than a straight line, during interphase of the mitotic cell cycle." [PomBase:mah] comment: In severe instances of this phenotype, microtubules grow long enough to curve around the cell tip. synonym: "elongated curved interphase microtubules" EXACT [PomBase:mah] synonym: "long curved cytoplasmic microtubules during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "long curved cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "long curved interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "long curved interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000233 ! long cytoplasmic microtubules is_a: FYPO:0003327 ! curved interphase microtubules created_by: midori creation_date: 2015-03-24T11:57:56Z [Term] id: FYPO:0004512 name: sensitive to EGTA def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to EGTA. Cells stop growing (and may die) at a concentration of EGTA that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to EGTA" EXACT [PomBase:mah] synonym: "sensitive to EGTA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to EGTA during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ethylene glycol bis(2-aminoethyl)tetraacetic acid" EXACT [CHEBI:30740] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-03-24T12:13:26Z [Term] id: FYPO:0004513 name: resistance to latrunculin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of latrunculin A than normal." [PomBase:mah] synonym: "resistance to LatA" EXACT [PomBase:mah] synonym: "resistance to latrunculin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to latrunculin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to latrunculin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-03-24T12:15:08Z [Term] id: FYPO:0004514 name: obsolete viable elongated aseptate vegetative cell def: "OBSOLETE. A cell phenotype in which a cell has no septum, is elongated, and is viable." [PomBase:mah] comment: This term was made obsolete because an elongated aseptate cell can never go on to divide, and therefore cannot be considered viable. synonym: "viable elongated aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable elongated aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable long aseptate cell" EXACT [PomBase:vw] is_obsolete: true created_by: midori creation_date: 2015-03-24T12:16:09Z [Term] id: FYPO:0004515 name: abnormal chromosome morphology, indistinct DNA def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which DNA is not visible in a distinct structure corresponding to the nucleus, but is instead diffuse or not visible at all." [PMID:25552606, PomBase:mah] synonym: "abnormal chromosome morphology, indistinct DNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromosome morphology, indistinct DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2015-03-24T12:26:57Z [Term] id: FYPO:0004516 name: decreased number of Rad52 foci during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is lower than normal." [PMID:22064477, PomBase:mah] synonym: "decreased number of Rad22 foci during vegetative growth" EXACT [PomBase:mah] synonym: "decreased number of Rad52 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced number of Rad52 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-03-24T12:28:30Z [Term] id: FYPO:0004517 name: viable vegetative cell enlarged around nucleus def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a diameter larger than normal only near the middle of the cell, around the nucleus." [PMID:25552606, PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable cell enlarged around nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "viable vegetative cell enlarged around nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape created_by: midori creation_date: 2015-03-24T12:30:06Z [Term] id: FYPO:0004518 name: inviable after spore germination, multiple cell divisions, branched, curved, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated) and is curved along the long axis, and undergoes two or more rounds of cell division and then dies." [PomBase:al, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, elongated, curved and branched cell" EXACT [PomBase:al] synonym: "inviable following spore germination, multiple cell divisions, branched, curved, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, branched, curved, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, branched, curved, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0002170 ! inviable after spore germination, multiple cell divisions, branched, elongated cell created_by: midori creation_date: 2015-03-31T12:12:54Z [Term] id: FYPO:0004519 name: abnormal DNA-directed DNA polymerase activity def: "A molecular function phenotype in which the observed rate or other catalytic property of a DNA-directed DNA polymerase activity is abnormal." [PomBase:mah] synonym: "abnormal DNA polymerase activity" BROAD [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-03-31T12:23:55Z [Term] id: FYPO:0004520 name: decreased DNA-directed DNA polymerase processivity def: "A molecular function phenotype in which the observed processivity of a DNA-directed DNA polymerase activity is lower than normal. Processivity refers to the number of nucleotides incorporated into a nascent DNA strand per polymerase-DNA binding event." [DOI:10.1038/npg.els.0001052, PomBase:mah] synonym: "decreased DNA polymerase processivity" BROAD [PomBase:mah] synonym: "reduced DNA-directed DNA polymerase processivity" EXACT [PomBase:mah] is_a: FYPO:0004519 ! abnormal DNA-directed DNA polymerase activity created_by: midori creation_date: 2015-03-31T12:26:08Z [Term] id: FYPO:0004521 name: inviable after spore germination, single or double cell division, branched, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated), and undergoes one or two rounds of cell division and then dies." [PomBase:mah] synonym: "inviable after spore germination, single or double cell division, elongated and branched cell" EXACT [PomBase:al] synonym: "inviable following spore germination, single or double cell division, branched, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, branched, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, branched, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0001512 ! branched, elongated cell is_a: FYPO:0002724 ! inviable after spore germination, single or double cell division, elongated cell created_by: midori creation_date: 2015-03-31T13:05:06Z [Term] id: FYPO:0004522 name: inviable after spore germination, single or double cell division, branched, curved, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated) and is curved along the long axis, and undergoes one or two rounds of cell division and then dies." [PomBase:mah] synonym: "inviable after spore germination, single or double cell division, elongated, curved and branched cell" EXACT [PomBase:al] synonym: "inviable following spore germination, single or double cell division, branched, curved, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, branched, curved, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, branched, curved, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0004521 ! inviable after spore germination, single or double cell division, branched, elongated cell is_a: FYPO:0004523 ! inviable after spore germination, single or double cell division, curved, elongated cell created_by: midori creation_date: 2015-03-31T13:05:36Z [Term] id: FYPO:0004523 name: inviable after spore germination, single or double cell division, curved, elongated cell def: "A phenotype in which a spore germinates to produce a cell that is elongated and is curved along the long axis, and undergoes one or two rounds of cell division and then dies." [PomBase:mah] synonym: "inviable after spore germination, single or double cell division, elongated and curved cell" EXACT [PomBase:al] synonym: "inviable following spore germination, single or double cell division, curved, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, curved, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, curved, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0002724 ! inviable after spore germination, single or double cell division, elongated cell is_a: FYPO:0005103 ! curved elongated vegetative cell created_by: midori creation_date: 2015-03-31T13:06:12Z [Term] id: FYPO:0004524 name: decreased number of Rad54 foci during cellular response to doxorubicin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad54 (also called Rhp54) accumulates is lower than normal during a cellular response to doxorubicin." [PMID:25701403, PomBase:mah] synonym: "decreased number of Rad54 foci during cellular response to doxorubicin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Rad54 foci during cellular response to doxorubicin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased number of Rhp54 foci during cellular response to doxorubicin" EXACT [PomBase:mah] synonym: "reduced number of Rad54 foci during cellular response to doxorubicin" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-03-31T13:20:50Z [Term] id: FYPO:0004525 name: abnormal membrane organization during mating def: "A cellular process phenotype in which cellular membrane organization is abnormal during mating." [PomBase:mah] synonym: "abnormal cellular membrane organization during mating" EXACT [GO:0061024, PomBase:mah] synonym: "abnormal membrane organisation during mating" EXACT [PomBase:mah] synonym: "abnormal membrane organization during conjugation" EXACT [PomBase:mah] synonym: "abnormal membrane organization during conjugation with cellular fusion" EXACT [GO:0000747] is_a: FYPO:0001013 ! abnormal membrane organization created_by: midori creation_date: 2015-03-31T13:30:32Z [Term] id: FYPO:0004526 name: abnormal regulation of transcription def: "A transcription regulation phenotype in which any process of regulation of transcription is abnormal." [PomBase:mah] synonym: "abnormal regulation of cellular transcription, DNA-dependent" EXACT [GO:0006355, PomBase:mah] synonym: "abnormal regulation of gene-specific transcription" RELATED [GO:006355, PomBase:mah] synonym: "abnormal regulation of transcription, DNA-dependent" EXACT [GO:0006355, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2015-03-31T13:35:07Z [Term] id: FYPO:0004527 name: abnormal regulation of transcription during vegetative growth alt_id: FYPO:0006471 def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which any process of regulation of transcription is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. There may be enough evidence to support annotation to a more specific term such as 'abnormal chromatin silencing' (FYPO:0000144); if not, it is safer to annotate to 'increased transcription during vegetative growth' (FYPO:0000780) or 'decreased transcription during vegetative growth' (FYPO:0000781) rather than explicitly claiming that an effect on regulation was observed. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal regulation of cellular transcription, DNA-dependent, during vegetative growth" EXACT [GO:0006355, PomBase:mah] synonym: "abnormal regulation of gene-specific transcription during vegetative growth" RELATED [GO:0006355, GO:006355, PomBase:mah] synonym: "abnormal regulation of transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of transcription, DNA-dependent, during vegetative growth" EXACT [GO:0006355, PomBase:mah] synonym: "abnormal transcriptional control during vegetative growth" BROAD [GO:0006355, PomBase:mah] is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0004526 ! abnormal regulation of transcription created_by: midori creation_date: 2015-03-31T13:37:24Z [Term] id: FYPO:0004528 name: abnormal mitochondrial translation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial translation is abnormal." [PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'altered protein level' (FYPO:0000834) or one of its descendants. synonym: "abnormal mitochondrial protein biosynthesis" EXACT [GO:0032543] synonym: "abnormal mitochondrial protein synthesis" EXACT [GO:0032543] synonym: "abnormal mitochondrial translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial translation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000632 ! mitochondrial translation phenotype created_by: midori creation_date: 2015-03-31T13:41:31Z [Term] id: FYPO:0004529 name: normal mitochondrial translation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial translation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. synonym: "normal mitochondrial protein biosynthesis" EXACT [GO:0032543] synonym: "normal mitochondrial protein synthesis" EXACT [GO:0032543] synonym: "normal mitochondrial translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial translation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-03-31T13:46:55Z [Term] id: FYPO:0004530 name: abolished mitochondrial translation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial translation does not occur." [PomBase:mah] comment: Note that this term should be used only when an experiment measures mitochondrial protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "abolished mitochondrial protein biosynthesis" EXACT [GO:0032543] synonym: "abolished mitochondrial protein synthesis" EXACT [GO:0032543] synonym: "abolished mitochondrial translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitochondrial translation during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial translation abolished" EXACT [PomBase:mah] is_a: FYPO:0004528 ! abnormal mitochondrial translation created_by: midori creation_date: 2015-03-31T13:47:36Z [Term] id: FYPO:0004531 name: inviable after spore germination, single or double cell division, small cell def: "A phenotype in which a spore germinates to produce a cell that is smaller than normal and undergoes one or two rounds of cell division." [PomBase:mah] synonym: "inviable after spore germination, single or double cell division, decreased cell size" EXACT [PomBase:mah] synonym: "inviable after spore germination, single or double cell division, reduced cell size" EXACT [PomBase:mah] synonym: "inviable following spore germination, single or double cell division, small cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell or double division, small cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, small cell" EXACT [PomBase:mah] is_a: FYPO:0000645 ! small vegetative cell is_a: FYPO:0001042 ! inviable after spore germination, single or double cell division is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology relationship: has_part FYPO:0000645 ! small vegetative cell created_by: midori creation_date: 2015-03-31T13:52:55Z [Term] id: FYPO:0004532 name: abnormal cell cycle arrest in mitotic M phase with abnormal spindle def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase under conditions where arrest does not normally occur, and the position or morphology of the mitotic spindle is abnormal." [PomBase:mah] comment: Metaphase is defined as the part of mitosis when chromosomes are aligned in the middle of the spindle. If no spindle is present, do not use this term, but consider 'abnormal cell cycle arrest in mitotic prophase' (FYPO:0003145). If you cannot tell whether a spindle is present, or if metaphase cannot be clearly detected, annotate to the more general term 'abnormal cell cycle arrest in mitotic M phase' (FYPO:0000608). synonym: "abnormal cell cycle arrest in mitotic M phase with abnormal mitotic spindle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic M phase with abnormal spindle during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic M phase with condensed chromosomes and abnormal spindle" RELATED [Pombase:vw] synonym: "abnormal mitotic cell cycle arrest in M phase with abnormal spindle" EXACT [GO:0000089] is_a: FYPO:0000338 ! abnormal mitotic spindle is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase created_by: midori creation_date: 2015-03-31T14:23:17Z [Term] id: FYPO:0004533 name: normal cell wall beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell wall beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "normal cell wall beta-glucan accumulation" RELATED [PomBase:mah] synonym: "normal cell wall beta-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell wall beta-glucan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001078 ! normal beta-glucan level created_by: midori creation_date: 2015-03-31T14:37:09Z [Term] id: FYPO:0004534 name: premature ascospore release from ascus def: "A cellular process phenotype in which the occurrence of ascospore release from an ascus begins earlier than normal." [GO:0071998, PMID:16751704, PomBase:mah] synonym: "accelerated ascospore release from ascus" RELATED [PomBase:al] synonym: "advanced ascospore release from ascus" EXACT [PomBase:mah] is_a: FYPO:0004272 ! abnormal ascospore release from ascus created_by: midori creation_date: 2015-03-31T14:39:36Z [Term] id: FYPO:0004535 name: inviable small spore with abnormal shape def: "A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a smaller volume than normal and an abnormal shape. An inviable spore does not germinate." [PomBase:mah] synonym: "inviable small abnormally shaped spore" EXACT [PomBase:mah] synonym: "inviable small spore with abnormal morphology" EXACT [PomBase:mah] synonym: "inviable spore with decreased size and abnormal shape" RELATED [PomBase:vw] synonym: "inviable spore with decreased spore size and abnormal shape" RELATED [PomBase:vw] synonym: "inviable spore with decreased spore volume and abnormal shape" EXACT [PomBase:mah] synonym: "inviable spore with decreased volume and abnormal shape" EXACT [PomBase:mah] synonym: "lethal; small spore with abnormal shape" EXACT [PomBase:mah] synonym: "spore germination abolished, small misshapen spores" RELATED [PomBase:mah] synonym: "spore germination abolished, small spore with abnormal shape" RELATED [PomBase:mah] synonym: "spore germination abolished, spore with abnormal shape and decreased cell size" RELATED [PomBase:vw] synonym: "spore germination abolished, spore with abnormal shape and decreased cell volume" EXACT [PomBase:mah] is_a: FYPO:0000307 ! inviable small spore is_a: FYPO:0002427 ! inviable spore with abnormal shape created_by: midori creation_date: 2015-04-02T13:48:30Z [Term] id: FYPO:0004536 name: abnormal response to mitotic cell cycle spindle assembly checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle spindle assembly checkpoint signaling is abnormal (does not occur, or occurs abnormally). Abnormal arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal." [PomBase:mah] synonym: "abnormal mitotic cell cycle spindle assembly checkpoint arrest" RELATED [PomBase:mah] synonym: "abnormal occurrence of mitotic cell cycle arrest resulting from spindle assembly checkpoint activation" RELATED [PomBase:mah] synonym: "abnormal occurrence of mitotic cell cycle arrest resulting from spindle assembly defective checkpoint activation" RELATED [PomBase:vw] synonym: "abnormal response to mitotic spindle assembly checkpoint signaling" EXACT [PomBase:mah] is_a: FYPO:0002517 ! abnormal response to mitotic cell cycle checkpoint signaling created_by: midori creation_date: 2015-04-02T14:00:45Z [Term] id: FYPO:0004537 name: mitotic spindle assembly checkpoint override def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle spindle assembly checkpoint signaling does not occur. As a result, the septation initiation network (SIN) signaling pathway is activated despite activation of the mitotic spindle assembly checkpoint (SAC). Normally, under conditions that activate the SAC, SIN activation is inhibited and the cell cycle arrests in anaphase. In this phenotype, premature SIN activation leads to premature cytokinesis and the formation of cut cells." [PMID:11952833, PomBase:mah, PomBase:vw] synonym: "abolished response to mitotic cell cycle spindle assembly checkpoint signaling" EXACT [PomBase:mah] synonym: "mitotic cell cycle spindle assembly checkpoint override" EXACT [PomBase:mah] synonym: "mitotic SAC override" EXACT [PomBase:mah] synonym: "septation initiation signaling activation in presence of active mitotic spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "SIN activation in presence of active mitotic SAC" EXACT [PomBase:mah] is_a: FYPO:0004536 ! abnormal response to mitotic cell cycle spindle assembly checkpoint signaling relationship: has_output FYPO:0000229 ! cut created_by: midori creation_date: 2015-04-02T14:10:40Z [Term] id: FYPO:0004538 name: microtubules present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more microtubules than normal." [PomBase:mah] synonym: "increased level of MTs" EXACT [PomBase:mah] synonym: "microtubules present in greater numbers" EXACT [PomBase:mah] synonym: "microtubules present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "microtubules present in increased numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2015-04-02T14:31:19Z [Term] id: FYPO:0004539 name: short interphase microtubules present in increased numbers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more, and shorter, cytoplasmic microtubules than normal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "broken interphase microtubules" RELATED [PomBase:vw] synonym: "short cytoplasmic microtubules present in increased numbers during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "short cytoplasmic microtubules present in increased numbers during mitotic interphase" EXACT [PomBase:mah] synonym: "short fragmented interphase microtubules" RELATED [PomBase:vw] synonym: "short interphase cytoplasmic microtubules present in increased numbers" EXACT [PomBase:mah] synonym: "short interphase microtubules present in greater numbers" EXACT [PomBase:mah] synonym: "short interphase microtubules present in increased numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004538 ! microtubules present in increased numbers is_a: FYPO:0006103 ! short interphase microtubules created_by: midori creation_date: 2015-04-02T14:32:10Z [Term] id: FYPO:0004540 name: increased chromatin silencing def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is increased. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah, PomBase:vw] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "increased chromatin silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2015-04-02T15:08:22Z [Term] id: FYPO:0004541 name: increased chromatin silencing at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere inner repeat regions is increased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "increased chromatin silencing at centromere imr" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromeric inner repeat region" EXACT [PomBase:mah] synonym: "increased heterochromatin silencing at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0005071 ! increased chromatin silencing at centromere created_by: midori creation_date: 2015-04-02T15:08:31Z [Term] id: FYPO:0004542 name: increased chromatin silencing at subtelomere alt_id: FYPO:0006367 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at subtelomeric regions is increased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "increased chromatin silencing at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased chromatin silencing at telomere" RELATED [PomBase:mah] is_a: FYPO:0000169 ! abnormal chromatin silencing at subtelomere is_a: FYPO:0000577 ! increased gene silencing is_a: FYPO:0004540 ! increased chromatin silencing created_by: midori creation_date: 2015-04-02T15:08:36Z [Term] id: FYPO:0004543 name: abnormal heterochromatin organization during vegetative growth def: "A cellular process phenotype in which any process of heterochromatin organization is abnormal in the vegetative growth phase of the life cycle. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin." [GO:0070828, PomBase:mah] synonym: "abnormal heterochromatin organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal heterochromatin organization during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2015-04-02T15:13:19Z [Term] id: FYPO:0004544 name: increased duration of heterochromatin maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of heterochromatin maintenance is longer than normal. Heterochromatin maintenance is the process that preserves heterochromatin in a stable functional or structural state." [GO:0070829, PomBase:mah] synonym: "increased duration of heterochromatin maintenance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of heterochromatin maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged heterochromatin maintenance" EXACT [PomBase:mah] is_a: FYPO:0004543 ! abnormal heterochromatin organization during vegetative growth created_by: midori creation_date: 2015-04-02T15:14:36Z [Term] id: FYPO:0004545 name: decreased proteasomal ubiquitin-dependent protein degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of proteasome-mediated, ubiquitin-dependent protein degradation is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased proteasomal ubiquitin-dependent protein breakdown" EXACT [GO:0043161] synonym: "decreased proteasomal ubiquitin-dependent protein catabolic process" EXACT [GO:0043161, PomBase:mah] synonym: "decreased proteasomal ubiquitin-dependent protein catabolism" EXACT [GO:0043161, PomBase:mah] synonym: "decreased proteasomal ubiquitin-dependent protein degradation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased proteasomal ubiquitin-dependent protein degradation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased proteasome-mediated ubiquitin-dependent protein catabolic process" EXACT [GO:0043161] synonym: "reduced proteasomal ubiquitin-dependent protein degradation" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth is_a: FYPO:0002797 ! decreased protein degradation created_by: midori creation_date: 2015-04-02T15:25:01Z [Term] id: FYPO:0004546 name: obsolete cut during cellular response to methyl methanesulfonate def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to methyl methanesulfonate. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "cut during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "cut during cellular response to MMS" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2015-04-08T16:04:01Z [Term] id: FYPO:0004547 name: increased protein localization to mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to mitochondrion" EXACT [PomBase:mah] synonym: "increased protein localization to mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to mitochondrion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004336 ! abnormal protein localization to mitochondrion created_by: midori creation_date: 2015-04-14T15:39:58Z [Term] id: FYPO:0004548 name: normal protein kinase activity during cellular response to hydroxyurea def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea." [PomBase:mah] synonym: "normal protein kinase activity during cellular response to HU" EXACT [PomBase:mah] synonym: "normal protein kinase activity in response to hydroxyurea" RELATED [PomBase:vw] is_a: FYPO:0003075 ! normal protein kinase activity created_by: midori creation_date: 2015-04-14T15:48:01Z [Term] id: FYPO:0004549 name: normal S-phase DNA damage checkpoint during cellular response to UV def: "A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage." [PomBase:mah] synonym: "normal intra-S phase DNA damage checkpoint during cellular response to UV" EXACT [GO:0031573] synonym: "normal mitotic S-phase DNA damage checkpoint during cellular response to UV" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint activation during cellular response to UV" EXACT [PomBase:al] synonym: "normal S-phase DNA damage checkpoint during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during cellular response to UV during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002102 ! normal mitotic DNA damage checkpoint during cellular response to UV is_a: FYPO:0003530 ! normal S-phase DNA damage checkpoint created_by: midori creation_date: 2015-04-14T15:50:36Z [Term] id: FYPO:0004550 name: abolished protein phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-04-14T15:54:04Z [Term] id: FYPO:0004551 name: abnormal mitotic cell cycle regulation during cellular response to ionizing radiation during mitotic S phase def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation exposure during mitotic S phase is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation. The most common abnormality is for the cell cycle to progress as in the absence of ionizing radiation." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to ionizing radiation during mitotic S phase" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following ionizing radiation during mitotic S phase" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to ionizing radiation during mitotic S phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to ionizing radiation during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to IR during mitotic S phase" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to ionizing radiation during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0003489 ! abnormal mitotic cell cycle regulation during cellular response to ionizing radiation created_by: midori creation_date: 2015-04-14T15:54:49Z [Term] id: FYPO:0004552 name: normal cell cycle regulation during cellular response to ionizing radiation during mitotic G2 phase def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation exposure during mitotic G2 phase is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation." [PomBase:mah] synonym: "normal cell cycle delay following ionizing radiation during mitotic G2 phase" EXACT [PomBase:al] synonym: "normal cell cycle regulation during cellular response to ionizing radiation during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell cycle regulation in response to ionizing radiation during mitotic G2 phase" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to ionizing radiation during G2 phase" EXACT [PomBase:mah] is_a: FYPO:0001927 ! normal cell cycle regulation during cellular response to ionizing radiation created_by: midori creation_date: 2015-04-14T16:05:18Z [Term] id: FYPO:0004553 name: obsolete cut during cellular response to ionizing radiation during mitotic S phase def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to ionizing radiation during mitotic S phase. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to ionizing radiation during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "cut during cellular response to ionizing radiation during S phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to IR during mitotic S phase" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation during cellular response to ionizing radiation during mitotic S phase" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2015-04-14T16:22:56Z [Term] id: FYPO:0004554 name: decreased protein phosphorylation during mitotic S phase during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during S phase of the mitotic cell cycle and during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to ionizing radiation during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to ionizing radiation during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic S phase during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic S phase during cellular response to IR" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to IR during mitotic S phase" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitotic S phase during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0004261 ! decreased protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation created_by: midori creation_date: 2015-04-14T16:24:55Z [Term] id: FYPO:0004555 name: growth auxotrophic for choline def: "Auxotrophy in which a cell is unable to synthesize choline, and therefore requires choline in the medium for vegetative cell growth." [PomBase:mah] synonym: "choline auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for choline during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for choline during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2015-04-14T16:35:19Z [Term] id: FYPO:0004556 name: decreased cellular phosphatidylcholine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylcholine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular PC level" EXACT [PomBase:mah] synonym: "decreased cellular phosphatidylcholine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphatidylcholine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased phosphatidylcholine accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphatidylcholine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2015-04-14T16:41:55Z [Term] id: FYPO:0004557 name: increased vegetative cell population growth def: "A cell growth phenotype in which vegetative cell population growth is increased relative to normal. Increased growth may reflect an increased growth rate (i.e. faster growth), growth that occurs to a greater extent than normal, or both." [PomBase:mah] synonym: "fast aerobic vegetative cell population growth" NARROW [PomBase:mah] synonym: "fast vegetative cell population growth" NARROW [PomBase:mah] synonym: "increased aerobic vegetative cell population growth" NARROW [PomBase:mah] is_a: FYPO:0003937 ! increased cell population growth created_by: midori creation_date: 2015-04-14T16:42:49Z [Term] id: FYPO:0004558 name: inviable after spore germination, without cell division, with abnormal cell morphology and abnormal actin cortical patch localization def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, has an abnormal morphology, and in which actin cortical patch localization is abnormal." [PMID:9765059, PomBase:mah] synonym: "inviable after spore germination, undivided cell, with abnormal cell morphology and abnormal actin cortical patch localization" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, with abnormal cell morphology and abnormal actin cortical patch localisation" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, with abnormal cell morphology and abnormal actin patch localization" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, with abnormal cell morphology and abnormal F-actin patch localization" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, with abnormal cell morphology and abnormal actin cortical patch localization" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with abnormal cell morphology and abnormal actin cortical patch localization" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with abnormal cell morphology and abnormal actin cortical patch localization" EXACT [PomBase:mah] is_a: FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth is_a: FYPO:0001991 ! inviable after spore germination, without cell division is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology relationship: has_part FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth created_by: midori creation_date: 2015-04-14T16:49:44Z [Term] id: FYPO:0004559 name: viable swollen spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "viable enlarged spheroid vegetative cell" RELATED [PomBase:mah] synonym: "viable enlarged volume spheroid vegetative cell" EXACT [PomBase:mah] synonym: "viable large spheroid vegetative cell" RELATED [PomBase:vw] synonym: "viable swollen rounded vegetative cell" EXACT [PomBase:mah] synonym: "viable swollen spheroid cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable swollen spheroid vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000945 ! swollen spheroid vegetative cell is_a: FYPO:0002380 ! viable spheroid vegetative cell is_a: FYPO:0002402 ! viable swollen vegetative cell with abnormal cell shape created_by: midori creation_date: 2015-04-21T11:02:12Z [Term] id: FYPO:0004560 name: sensitive to BE49385A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to BE49385A (a GPI synthesis inhibitor, also called YW3548). Cells stop growing (and may die) at a concentration of BE49385A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to BE49385A" EXACT [PomBase:mah] synonym: "sensitive to BE49385A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to BE49385A during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to YW3548" EXACT [CHEBI:79385, PMID:11297516] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-04-21T11:17:51Z [Term] id: FYPO:0004561 name: resistance to BE49385A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of BE49385A (a GPI synthesis inhibitor, also called YW3548) than normal." [PomBase:mah] synonym: "resistance to BE49385A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to BE49385A during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to YW3548" EXACT [CHEBI:79385, PMID:11297516] synonym: "resistant to BE49385A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-04-21T11:23:28Z [Term] id: FYPO:0004562 name: binucleate aseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and no septum." [PomBase:mah] synonym: "binucleate aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "binucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "dikaryosis" RELATED [PomBase:mah] is_a: FYPO:0000949 ! aseptate is_a: FYPO:0001222 ! binucleate vegetative cell relationship: has_part FYPO:0000949 ! aseptate relationship: has_part FYPO:0001222 ! binucleate vegetative cell created_by: midori creation_date: 2015-04-21T11:29:09Z [Term] id: FYPO:0004563 name: abnormal alpha-galactosidase activity def: "A molecular function phenotype in which the observed rate of alpha-galactosidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-04-21T11:42:08Z [Term] id: FYPO:0004564 name: increased alpha-galactosidase activity def: "A molecular function phenotype in which the observed rate of alpha-galactosidase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004563 ! abnormal alpha-galactosidase activity created_by: midori creation_date: 2015-04-21T11:42:13Z [Term] id: FYPO:0004565 name: increased transcription of pheromone response gene mRNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of pheromone response genes is increased. Pheromone response genes are normally transcribed in response to a pheromone stimulus." [PMID:15580593, PomBase:al, PomBase:mah] synonym: "increased transcription of pheromone response gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription of pheromone response gene RNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2015-04-21T11:54:28Z [Term] id: FYPO:0004566 name: sensitive to caffeine during meiosis II def: "A phenotype in which cells show increased sensitivity to caffeine during the second meiotic nuclear division. Cells stop growing (and may die) at a concentration of caffeine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to caffeine during meiosis II" EXACT [PomBase:mah] synonym: "sensitive to caffeine during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002683 ! increased sensitivity to chemical created_by: midori creation_date: 2015-04-21T12:19:16Z [Term] id: FYPO:0004567 name: fragmented spindle during meiosis II def: "A cell phenotype which the spindle is broken into fragments during the second meiotic nuclear division." [PomBase:mah] synonym: "fragmented meiotic spindle during meiosis II" EXACT [PomBase:mah] synonym: "fragmented spindle during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "fragmented spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle fragmentation during meiosis II" EXACT [PomBase:vw] is_a: FYPO:0000734 ! abnormal meiotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2015-04-21T12:45:06Z [Term] id: FYPO:0004568 name: normal spindle def: "A physical cellular phenotype in which the presence, distribution, or morphology of the mitotic or meiotic spindle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2015-04-21T12:59:45Z [Term] id: FYPO:0004569 name: normal spindle during meiosis I def: "A physical cellular phenotype in which the presence, distribution, or morphology of the meiotic spindle is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division." [PomBase:mah] synonym: "normal meiosis I spindle" EXACT [PomBase:al] synonym: "normal meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "normal spindle during first meiotic nuclear division" RELATED [PomBase:mah] is_a: FYPO:0004568 ! normal spindle created_by: midori creation_date: 2015-04-21T13:01:43Z [Term] id: FYPO:0004570 name: decreased meiotic sister chromatid separation def: "A cellular process phenotype in which the occurrence of meiotic sister chromatid separation is decreased." [PomBase:mah] synonym: "decreased chromosome separation during meiosis II" EXACT [PomBase:al] synonym: "reduced meiotic sister chromatid separation" EXACT [PomBase:mah] is_a: FYPO:0005509 ! abnormal meiotic sister chromatid segregation created_by: midori creation_date: 2015-04-21T13:22:43Z [Term] id: FYPO:0004571 name: increased RNA level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to hydrogen peroxide" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to H2O2" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to hydrogen peroxide" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-04-21T13:36:54Z [Term] id: FYPO:0004572 name: decreased exocytosis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which exocytosis occurs to a lower extent than normal. Exocytosis is the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. A phenotype may affect exocytosis of all cargoes, or of specific cargo such as a particular protein." [GO:0006887, PomBase:mah] synonym: "decreased exocytosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced exocytosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002089 ! abnormal exocytosis during vegetative growth created_by: midori creation_date: 2015-04-21T13:38:15Z [Term] id: FYPO:0004573 name: increased telomeric transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of non-coding RNA transcribed from telomeric regions measured in a cell is higher than normal." [PMID:25398909, PomBase:mah, SO:0001927] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased telomeric lncRNA level" EXACT [PomBase:al] synonym: "increased telomeric transcript accumulation" RELATED [PomBase:mah] synonym: "increased telomeric transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased telomeric transcript level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2015-04-21T13:59:10Z [Term] id: FYPO:0004574 name: DEPRECATED increased subtelomere-derived RNA level comment: Duplicate meaning property_value: seeAlso FYPO:0005917 is_obsolete: true [Term] id: FYPO:0004575 name: increased histone H3-K9 acetylation at subtelomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in subtelomeric regions occurs to a greater extent than normal." [PMID:25398909, PomBase:mah] synonym: "increased histone H3-K9 acetylation at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 acetylation at subtelomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9 acetylation at subtelomere during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "increased subtelomeric histone H3K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2015-04-21T14:13:15Z [Term] id: FYPO:0004576 name: decreased histone H3-K9 acetylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in subtelomeric regions occurs to a lower extent than normal." [PMID:25398909, PomBase:mah] synonym: "decreased histone H3-K9 acetylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 acetylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 acetylation at subtelomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9 acetylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "decreased subtelomeric histone H3K9 acetylation during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "reduced histone H3-K9 acetylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001442 ! decreased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2015-04-21T14:14:18Z [Term] id: FYPO:0004577 name: decreased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in subtelomeric regions occurs to a lower extent than normal." [PMID:25398909, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at subtelomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased subtelomeric histone H3K9 trimethylation during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000882 ! decreased histone H3-K9 trimethylation during vegetative growth created_by: midori creation_date: 2015-04-21T14:15:38Z [Term] id: FYPO:0004578 name: decreased level of histone H3 in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased accumulation of histone H3 in cell" RELATED [PomBase:mah] synonym: "decreased cellular histone H3 level" EXACT [PomBase:mah] synonym: "decreased histone H3 level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of histone H3 in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of histone H3 in cell during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of histone H3 in cell" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2015-04-21T14:20:31Z [Term] id: FYPO:0004579 name: normal transposable element-derived small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal transposable element-derived small RNA accumulation" RELATED [PomBase:mah] synonym: "normal transposable element-derived small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transposable element-derived small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal transposable element-derived small RNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2015-04-21T14:23:38Z [Term] id: FYPO:0004580 name: increased number of plasmid catenanes def: "A cell phenotype in which a cell contains a larger number plasmid catenanes than normal. Plasmid catenanes are structures formed by two or more copies of a circular plasmid DNA molecule catenated together." [PMID:15957215, PomBase:mah] synonym: "increased number of catenated plasmids" EXACT [PomBase:mah] synonym: "increased number of plasmid catenanes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of plasmid catenanes during vegetative growth" EXACT [PomBase:mah] synonym: "increased plasmid catenane level" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2015-04-21T15:00:53Z [Term] id: FYPO:0004581 name: increased transcriptional response to pheromone def: "A transcription regulation phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter is increased." [GO:0007329, PomBase:mah] synonym: "increased positive regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0007329] is_a: FYPO:0000623 ! abnormal positive regulation of transcription is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2015-04-21T15:25:40Z [Term] id: FYPO:0004582 name: increased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but its occurrence is increased." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "increased cell cycle arrest in mitotic G1 phase during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "increased cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "increased mitotic cell cycle arrest in G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] is_a: FYPO:0000711 ! decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation created_by: midori creation_date: 2015-04-21T15:28:40Z [Term] id: FYPO:0004583 name: abnormal meiotic chromosome condensation def: "A cellular process phenotype in which meiotic chromosome condensation is abnormal." [PMID:23263988, PomBase:mah] synonym: "abnormal chromosome condensation during meiosis I" EXACT [PMID:23263988, PomBase:mah] synonym: "abnormal chromosome condensation during meiotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000159 ! abnormal chromosome condensation created_by: midori creation_date: 2015-04-29T11:04:41Z [Term] id: FYPO:0004584 name: abnormally arrested meiosis I with four spindle pole bodies def: "A cellular process phenotype in which the first meiotic nuclear division is arrested under conditions where arrest does not normally occur, and in which arrested cells contain four spindle pole bodies. Cells may contain one or two spindles, but the nucleus does not divide." [PMID:9763441, PomBase:mah] synonym: "abnormally arrested first meiotic nuclear division with four spindle pole bodies" EXACT [PomBase:mah] synonym: "abnormally arrested meiosis I with duplicated spindle pole bodies" EXACT [PomBase:al] synonym: "abnormally arrested meiosis I with four SPBs" EXACT [PomBase:mah] synonym: "cell cycle arrest in meiosis I with four spindle pole bodies" EXACT [PomBase:mah] is_a: FYPO:0002817 ! abnormally arrested meiosis I is_a: FYPO:0004609 ! spindle pole bodies present in increased numbers during meiosis relationship: has_part FYPO:0004609 ! spindle pole bodies present in increased numbers during meiosis created_by: midori creation_date: 2015-04-29T11:15:56Z [Term] id: FYPO:0004585 name: abnormal linear element morphology def: "A physical cellular phenotype in which the size, shape, or structure of linear elements is abnormal." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2015-04-29T11:21:08Z [Term] id: FYPO:0004586 name: sensitive to caffeine and hydroxyurea def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of caffeine and hydroxyurea. Cells stop growing (and may die) at concentrations of caffeine and hydroxyurea that allow wild type cells to grow." [PMID:10757807, PomBase:mah] synonym: "hypersensitive to caffeine and hydroxyurea" EXACT [PomBase:mah] synonym: "sensitive to caffeine and HU" EXACT [PomBase:mah] synonym: "sensitive to caffeine and hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to caffeine and hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to caffeine and hydroxyurea in combination" EXACT [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-04-29T11:46:35Z [Term] id: FYPO:0004587 name: abolished cell population growth on urea nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing urea as the nitrogen source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with urea as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished urea utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on urea nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on urea nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2015-04-29T11:59:27Z [Term] id: FYPO:0004588 name: abnormal mitosis following normal mitosis def: "A cellular process phenotype in which mitosis takes place abnormally after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase." [PomBase:mah] comment: This phenotype affects the second round of mitosis to take place after a mutation exerts its effect. For example, if a conditional mutant is shifted to restrictive conditions in G1 or S phase and the first mitosis thereafter is normal, but the second is not (even if cells are returned to permissive conditions), this term is applicable. synonym: "abnormal mitosis following normal mitosis and interphase" EXACT [PomBase:mah] synonym: "abnormal mitosis following normal mitosis and passage through mitotic G1 phase" EXACT [PomBase:vw] synonym: "abnormal mitosis following normal mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic nuclear division following normal mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal nuclear division following normal nuclear division during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000337 ! abnormal mitosis is_a: FYPO:0004593 ! abnormal vegetative cell phenotype following normal mitosis created_by: midori creation_date: 2015-04-29T12:16:40Z [Term] id: FYPO:0004589 name: abnormal gamma-tubulin complex localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which localization of the gamma-tubulin complex to the spindle pole body is abnormal." [PomBase:mah] synonym: "abnormal gamma-tubulin complex localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to mitotic SPB" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001440 ! abnormal protein complex localization created_by: midori creation_date: 2015-04-29T15:36:44Z [Term] id: FYPO:0004590 name: abnormal gamma-tubulin complex localization to mitotic spindle pole body following normal mitosis def: "A cellular process phenotype in which localization of the gamma-tubulin complex to the spindle pole body takes place abnormally after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase." [PomBase:mah] comment: This phenotype affects the second round of mitosis to take place after a mutation exerts its effect. For example, if a conditional mutant is shifted to restrictive conditions in G1 or S phase and gamma-tubulin complex localization thereafter is normal during the first, but not the second mitotic division (even if cells are returned to permissive conditions), this term is applicable. synonym: "abnormal gamma-tubulin complex localisation to mitotic spindle pole body following normal mitosis" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to mitotic SPB following normal mitosis" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to mitotic spindle pole body following normal mitosis and interphase" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to mitotic spindle pole body following normal mitosis and passage through mitotic G1 phase" EXACT [PomBase:vw] synonym: "abnormal gamma-tubulin complex localization to mitotic spindle pole body following normal mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal gamma-tubulin complex localization to mitotic spindle pole body nuclear division following normal mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal gamma-tubulin complex localization to spindle pole body following normal nuclear division during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004589 ! abnormal gamma-tubulin complex localization to mitotic spindle pole body is_a: FYPO:0004593 ! abnormal vegetative cell phenotype following normal mitosis created_by: midori creation_date: 2015-04-29T15:40:33Z [Term] id: FYPO:0004591 name: monopolar mitotic spindle following normal mitosis def: "A physical cellular phenotype in which the mitotic spindle forms with microtubules emanating from only one pole after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase." [PomBase:mah] comment: This phenotype affects the second round of mitosis to take place after a mutation exerts its effect. For example, if a conditional mutant is shifted to restrictive conditions in G1 or S phase and the first mitosis thereafter is normal, but the spindle becomes monopolar in the second (even if cells are returned to permissive conditions), this term is applicable. synonym: "monopolar mitotic spindle following normal mitosis and interphase" EXACT [PomBase:mah] synonym: "monopolar mitotic spindle following normal mitosis and passage through mitotic G1 phase" EXACT [PomBase:vw] synonym: "monopolar mitotic spindle following normal mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "monopolar mitotic spindle following normal mitotic nuclear division" EXACT [GO:0140014] synonym: "monopolar mitotic spindle following normal nuclear division during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000276 ! monopolar mitotic spindle is_a: FYPO:0004593 ! abnormal vegetative cell phenotype following normal mitosis created_by: midori creation_date: 2015-04-29T15:54:05Z [Term] id: FYPO:0004592 name: cut following normal mitosis def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell becomes cut after it has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This phenotype affects the second round of mitosis to take place after a mutation exerts its effect. For example, if a conditional mutant is shifted to restrictive conditions in G1 or S phase and the first mitosis thereafter is normal, but the second results in a cut cell (even if cells are returned to permissive conditions), this term is applicable. synonym: "cut following normal mitosis and interphase" EXACT [PomBase:mah] synonym: "cut following normal mitosis and passage through mitotic G1 phase" EXACT [PomBase:vw] synonym: "cut following normal mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "cut following normal mitotic nuclear division" EXACT [GO:0140014] synonym: "cut following normal nuclear division during mitotic cell cycle" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation with normal mitosis" EXACT [PomBase:vw] is_a: FYPO:0000229 ! cut is_a: FYPO:0000337 ! abnormal mitosis is_a: FYPO:0004593 ! abnormal vegetative cell phenotype following normal mitosis is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth relationship: has_part FYPO:0004588 ! abnormal mitosis following normal mitosis created_by: midori creation_date: 2015-04-29T15:56:48Z [Term] id: FYPO:0004593 name: abnormal vegetative cell phenotype following normal mitosis def: "A phenotype that shows detectable differences from normal at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle, and after it has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase." [PomBase:mah] comment: This term groups phenotypes that affect the second round of mitosis to take place after a mutation exerts its effect. For example, if a conditional mutant is shifted to restrictive conditions in G1 or S phase and the first mitosis thereafter is normal, but an abnormality arises in the second (even if cells are returned to permissive conditions), a descendant of this term is applicable. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cell phenotype following normal mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vegetative cell phenotype following normal mitosis and interphase" EXACT [PomBase:mah] synonym: "abnormal vegetative cell phenotype following normal mitosis and passage through mitotic G1 phase" EXACT [PomBase:vw] synonym: "abnormal vegetative cell phenotype following normal mitotic nuclear division" EXACT [GO:0140014] synonym: "abnormal vegetative cell phenotype following normal nuclear division during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2015-04-29T15:59:40Z [Term] id: FYPO:0004594 name: branched, elongated, septated cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched, septated and elongated." [PomBase:jh, PomBase:mah, PomBase:vw] comment: These cells often form a branch at a non-right angle to the long axis of the mother cell, near the septum. synonym: "branched, elongated, septated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "branched, elongated, septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, elongated, septated vegetative cell" EXACT [PomBase:mah] synonym: "branched, long, septated cell" EXACT [PomBase:vw] is_a: FYPO:0001512 ! branched, elongated cell is_a: FYPO:0004750 ! elongated septated vegetative cell created_by: midori creation_date: 2015-04-29T16:37:35Z [Term] id: FYPO:0004595 name: abnormal gamma-tubulin complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gamma-tubulin complex assembly is abnormal." [PomBase:mah] synonym: "abnormal gamma-tubulin complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal gamma-tubulin complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2015-04-29T16:57:11Z [Term] id: FYPO:0004596 name: abnormal negative regulation of DNA replication initiation during mitotic G2 phase resulting in complete rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, with replication reinitiating during G2 phase of the mitotic cell cycle and resulting in one or more rounds of rereplication of the entire genome." [PMID:11532929, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during G2 phase resulting in complete rereplication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during mitotic G2 phase during vegetative growth, resulting in complete rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during mitotic G2 phase resulting in complete re-replication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation during mitotic G2 phase resulting in complete rereplication" EXACT [PomBase:mah] is_a: FYPO:0001425 ! abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication created_by: midori creation_date: 2015-04-29T16:58:57Z [Term] id: FYPO:0004597 name: replication origin firing during mitotic G2 phase def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which DNA replication is initiated at one or more origins during G2 phase of the mitotic cell cycle." [PMID:11532929, PomBase:mah] synonym: "replication origin firing during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "replication origin firing during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of mitotic DNA replication initiation created_by: midori creation_date: 2015-04-29T17:01:38Z [Term] id: FYPO:0004598 name: increased protein localization to chromatin during mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during G2 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin during mitotic G2 phase" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-04-29T17:03:36Z [Term] id: FYPO:0004599 name: increased rate of DNA replication during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA replication is increased." [PomBase:mah] synonym: "increased rate of DNA replication during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2015-04-29T17:06:18Z [Term] id: FYPO:0004600 name: normal transcriptional response to pheromone def: "A conjugation phenotype in which regulation of transcription in response to mating pheromone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0046019, PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2015-04-29T17:08:24Z [Term] id: FYPO:0004601 name: normal S-phase DNA damage checkpoint during cellular response to hydroxyurea def: "A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type) when the cell is exposed to hydroxyurea. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage." [PomBase:mah] synonym: "normal intra-S phase DNA damage checkpoint during cellular response to hydroxyurea" EXACT [GO:0031573] synonym: "normal mitotic S-phase DNA damage checkpoint during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint activation during cellular response to hydroxyurea" EXACT [PomBase:al] synonym: "normal S-phase DNA damage checkpoint during cellular response to HU" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during cellular response to hydroxyurea during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001929 ! normal cell cycle regulation during cellular response to hydroxyurea is_a: FYPO:0003530 ! normal S-phase DNA damage checkpoint created_by: midori creation_date: 2015-04-30T15:20:21Z [Term] id: FYPO:0004602 name: normal linear element morphology def: "A physical cellular phenotype in which the size, shape, or structure of all or part of the linear element is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2015-04-30T15:25:23Z [Term] id: FYPO:0004603 name: inviable after spore germination, without cell division, elongated cell def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide and is elongated." [PMID:7957061, PomBase:mah] synonym: "inviable following spore germination, without cell division, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2015-05-01T14:49:23Z [Term] id: FYPO:0004604 name: decreased chromatin silencing at subtelomere alt_id: FYPO:0003880 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at subtelomeric regions is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased chromatin silencing at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at telomere" RELATED [PomBase:mah] synonym: "reduced chromatin silencing at subtelomere" EXACT [PomBase:mah] is_a: FYPO:0000169 ! abnormal chromatin silencing at subtelomere is_a: FYPO:0002353 ! decreased chromatin silencing created_by: midori creation_date: 2015-05-01T14:58:39Z [Term] id: FYPO:0004605 name: decreased distance travelled by the spindle pole body during horsetail movement def: "A cellular process phenotype in which the total distance travelled by the SPB during horsetail movement is decreased. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. PMID:24954111" [GO:0030989, PomBase:mlr] synonym: "decreased dynein-driven meiotic oscillatory nuclear movement" RELATED [GO:0030989] synonym: "decreased horsetail nuclear movement" RELATED [GO:0030989] synonym: "reduced horsetail movement" RELATED [PomBase:mah] is_a: FYPO:0000197 ! abnormal horsetail movement created_by: midori creation_date: 2015-05-01T15:08:53Z [Term] id: FYPO:0004606 name: normal protein level during meiotic cell cycle def: "A cell phenotype in which the amount of protein measured in a cell during the meiotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein level during meiotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein accumulation during meiotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004083 ! normal protein level created_by: midori creation_date: 2015-05-01T15:22:58Z [Term] id: FYPO:0004607 name: abnormal spindle pole body morphology def: "A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "abnormal SPB morphology" EXACT [PomBase:mah] synonym: "abnormal spindle pole body structure" NARROW [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2015-05-01T15:25:17Z [Term] id: FYPO:0004608 name: abnormal spindle pole body morphology during meiosis II def: "A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal during the second meiotic nuclear division." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "abnormal SPB morphology during meiosis II" EXACT [PomBase:mah] synonym: "abnormal spindle pole body morphology during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal spindle pole body structure during meiosis II" NARROW [PomBase:mah] is_a: FYPO:0006406 ! abnormal spindle pole body morphology during meiotic cell cycle relationship: output_of FYPO:0003561 ! abnormal prospore-specific spindle pole body remodeling created_by: midori creation_date: 2015-05-01T15:25:51Z [Term] id: FYPO:0004609 name: spindle pole bodies present in increased numbers during meiosis def: "A physical cellular phenotype in which cells contain more spindle pole bodies (SPBs) than normal during one or both meiotic nuclear divisions. In this phenotype, extra SPBs typically contain normal components but seldom attach to spindle microtubules." [PMID:15569158, PomBase:mah] synonym: "excess meiotic spindle pole bodies present" EXACT [PomBase:mah] synonym: "excess spindle pole bodies present during meiosis" EXACT [PomBase:mah] synonym: "extra spindle pole bodies present during meiosis" EXACT [PomBase:mah] synonym: "pseudo-SPBs present during meiosis" EXACT [PMID:15569158] synonym: "SPBs present in increased numbers during meiosis" EXACT [PomBase:mah] synonym: "spindle pole bodies present in greater numbers during meiosis" EXACT [PomBase:mah] synonym: "spindle pole bodies present in increased numbers during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component relationship: output_of FYPO:0007259 ! increased meiotic spindle pole body duplication created_by: midori creation_date: 2015-05-01T15:50:12Z [Term] id: FYPO:0004610 name: increased duration of meiotic prophase I def: "A cellular process phenotype in which the duration of prophase of the first meiotic nuclear division is longer than normal." [PomBase:mah] synonym: "long meiotic prophase I" EXACT [PomBase:mah] synonym: "prolonged meiotic prophase I" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2015-05-01T16:10:09Z [Term] id: FYPO:0004611 name: long interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "elongated interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "long cytoplasmic microtubules during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "long cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "long interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "long interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000233 ! long cytoplasmic microtubules is_a: FYPO:0003625 ! abnormal microtubule cytoskeleton morphology during mitotic interphase is_a: FYPO:0006101 ! abnormal interphase microtubules created_by: midori creation_date: 2015-05-01T16:15:17Z [Term] id: FYPO:0004612 name: long astral microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form astral microtubules that are longer than normal." [PomBase:mah] synonym: "elongated astral microtubules" EXACT [PomBase:mah] synonym: "long astral microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long astral microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "long cytoplasmic astral microtubules" EXACT [PomBase:vw] is_a: FYPO:0000233 ! long cytoplasmic microtubules created_by: midori creation_date: 2015-05-01T16:23:12Z [Term] id: FYPO:0004613 name: abolished microtubule attachment to spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the spindle pole body is not attached to any interphase cytoplasmic microtubules; as a result, the microtubules are not connected to the nucleus. Normally, the spindle pole body is attached to at least one cytoplasmic microtubule bundle." [PMID:15772152, PomBase:mah, PomBase:vw] comment: This phenotype may result from either absence of the microtubule bundle that would normally attach to the SPB, or from a problem with the SPB-microtubule attachment process. synonym: "abolished microtubule attachment to nucleus" BROAD [PomBase:vw] synonym: "abolished microtubule attachment to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished microtubule attachment to spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules absent from mitotic spindle pole body" EXACT [PomBase:vw] synonym: "cytoplasmic microtubules detached from spindle pole body" EXACT [PomBase:vw] synonym: "interphase microtubules detached from nucleus" EXACT [PomBase:vw] synonym: "interphase microtubules detached from spindle pole body" EXACT [Pombase:vw] synonym: "SPB detached from cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "spindle pole body detached from cytoplasmic microtubules" EXACT [PomBase:mah] is_a: FYPO:0001474 ! abnormal mitotic spindle pole body morphology created_by: midori creation_date: 2015-05-05T13:11:24Z [Term] id: FYPO:0004614 name: abnormal microtubule polymerization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, is abnormal." [GO:0046785, PomBase:mah] synonym: "abnormal microtubule growth" EXACT [PomBase:vw] synonym: "abnormal microtubule polymerisation" EXACT [PomBase:mah] synonym: "abnormal microtubule polymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal microtubule rescue" RELATED [PomBase:mah] is_a: FYPO:0000901 ! abnormal microtubule dynamics during vegetative growth created_by: midori creation_date: 2015-05-05T13:33:03Z [Term] id: FYPO:0004615 name: increased rate of mitotic interphase microtubule polymerization def: "A microtubule cytoskeleton organization phenotype observed during interphase of the mitotic cell cycle in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a cytoplasmic microtubule, occurs at a higher rate, or speed, than normal." [GO:0046785, PomBase:mah] synonym: "increased interphase microtubule plus end growth rate" EXACT [PomBase:vw] synonym: "increased interphase microtubule polymerization rate" EXACT [PomBase:mah] synonym: "increased rate of cytoplasmic microtubule polymerization during mitotic interphase" EXACT [PomBase:mah] synonym: "increased rate of interphase cytoplasmic microtubule polymerization" EXACT [PomBase:mah] synonym: "increased rate of interphase microtubule growth" EXACT [PomBase:vw] synonym: "increased rate of interphase microtubule polymerisation" EXACT [PomBase:mah] synonym: "increased rate of interphase microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of interphase microtubule polymerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007970 ! increased rate of microtuble polymerization during vegetative growth created_by: midori creation_date: 2015-05-05T13:39:51Z [Term] id: FYPO:0004616 name: abolished cytoplasmic microtubule depolymerization at plus end at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule, does not occur at the plus end of the microtubule at the cell tip. Normally, rapid depolymerization takes place when the growing plus end of the microtubule reaches the cell tip." [GO:0070462, PMID:15772152, PomBase:mah] synonym: "abolished cytoplasmic microtubule depolymerisation at plus end at cell tip" EXACT [PomBase:mah] synonym: "abolished cytoplasmic microtubule depolymerization at plus end at cell end" EXACT [PomBase:mah] synonym: "abolished cytoplasmic microtubule depolymerization at plus end at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished cytoplasmic microtubule depolymerization at plus end at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abolished microtubule catastrophe at cell tip" RELATED [PomBase:vw] synonym: "abolished microtubule plus end shrinkage at cell tip" RELATED [PomBase:vw] synonym: "abolished plus-end specific microtubule depolymerization at cell tip" EXACT [GO:0070462] synonym: "cytoplasmic microtubule depolymerization at plus end at cell tip abolished" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth created_by: midori creation_date: 2015-05-05T13:59:40Z [Term] id: FYPO:0004617 name: obsolete increased rate of microtubule depolymerization at minus end def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which minus-end specific microtubule depolymerization, i.e. the removal of tubulin dimers from the minus end of a microtubule, occurs at a greater rate, or speed, than normal." [GO:0036078, PomBase:mah] comment: In wild-type cells, microtubule minus ends are capped by the gamma-tubulin complex (they are not dynamic, they don't grow or shrink), so the minus end depolymerisation speed of the wild type in normal conditions cannot be measured and compared. It is possible to measure shrinkage speeds of minus ends in wild-type cells, specifically using laser ablation (cutting microtubules). This leads to minus end depolymerisation. It could be that in a certain study this minus end depolymerisation is compared in two genetic backgrounds. In that case, however, the phenotype could specify "after laser ablation". synonym: "decreased microtubule stability" RELATED [PomBase:vw] synonym: "increased microtubule depolymerization rate at minus end" EXACT [PomBase:mah] synonym: "increased microtubule minus end shrinkage" RELATED [PomBase:vw] synonym: "increased rate of microtubule catastrophe at minus end" RELATED [PomBase:mah] synonym: "increased rate of microtubule depolymerisation at minus end" EXACT [PomBase:mah] synonym: "increased rate of microtubule depolymerization at minus end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of microtubule depolymerization at minus end during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of minus-end specific microtubule depolymerization" EXACT [GO:0036078] is_obsolete: true consider: FYPO:0008006 created_by: midori creation_date: 2015-05-05T14:03:39Z [Term] id: FYPO:0004618 name: astral microtubules absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable astral microtubules." [PomBase:mah] synonym: "absent astral microtubules" EXACT [PomBase:mah] synonym: "astral microtubules absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "astral microtubules absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic astral microtubules absent from cell" EXACT [PomBase:vw] is_a: FYPO:0004702 ! cytoplasmic microtubules absent from cell created_by: midori creation_date: 2015-05-05T14:20:14Z [Term] id: FYPO:0004619 name: cytoplasmic microtubules nucleated from eMTOC absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable cytoplasmic microtubules nucleated from the equatorial microtubule organizing center (eMTOC)." [PMID:15772152, PomBase:mah] synonym: "cytoplasmic microtubules nucleated from eMTOC absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubules nucleated from eMTOC absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules nucleated from equatorial microtubule organizing center absent from cell" EXACT [PomBase:mah] is_a: FYPO:0004702 ! cytoplasmic microtubules absent from cell created_by: midori creation_date: 2015-05-05T15:03:04Z [Term] id: FYPO:0004620 name: abnormal spindle disassembly def: "A cellular process phenotype in which spindle disassembly is abnormal. Spindle disassembly is the controlled breakdown of the spindle." [GO:0051230, PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization created_by: midori creation_date: 2015-05-05T15:09:51Z [Term] id: FYPO:0004621 name: abnormal mitotic spindle disassembly def: "A cellular process phenotype in which disassembly of the mitotic spindle is abnormal." [PomBase:mah] synonym: "abnormal spindle disassembly during mitosis" EXACT [PomBase:mah] synonym: "abnormal spindle disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle disassembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth is_a: FYPO:0004620 ! abnormal spindle disassembly relationship: part_of FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2015-05-05T15:10:09Z [Term] id: FYPO:0004622 name: abolished mitotic spindle disassembly def: "A cell phenotype in which mitotic spindle disassembly does not occur." [PomBase:mah] comment: When the mitotic spindle is not disassembled, it can become bent or S-shaped, and remains present in the cell after anaphase. synonym: "abolished mitotic spindle disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished spindle disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle disassembly involved in mitosis abolished" EXACT [PomBase:mah] is_a: FYPO:0004621 ! abnormal mitotic spindle disassembly created_by: midori creation_date: 2015-05-05T15:11:01Z [Term] id: FYPO:0004623 name: abolished astral microtubule anchoring at mitotic spindle pole body def: "A cell phenotype in which astral microtubule anchoring at the mitotic spindle pole body does not occur." [PMID:15004232, PomBase:mah] synonym: "abolished astral microtubule anchoring at mitotic SPB" EXACT [PomBase:mah] synonym: "abolished astral microtubule anchoring at mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished astral microtubule anchoring at mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "astral microtubule anchoring at mitotic spindle pole body abolished" EXACT [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization created_by: midori creation_date: 2015-05-05T15:20:37Z [Term] id: FYPO:0004624 name: abolished eMTOC assembly def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which equatorial microtubule organizing center (eMTOC) assembly does not occur. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center." [GO:1904185, PMID:15004232, PomBase:mah] synonym: "abolished eMTOC assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished eMTOC assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished eMTOC formation" EXACT [PomBase:mah] synonym: "abolished equatorial microtubule organizing center assembly" EXACT [GO:1904185] synonym: "abolished equatorial microtubule organizing center formation" EXACT [GO:1904185] synonym: "eMTOC abolished" EXACT [PomBase:mah] is_a: FYPO:0005690 ! abnormal eMTOC assembly relationship: has_output FYPO:0005687 ! eMTOC absent from cell created_by: midori creation_date: 2015-05-05T15:24:59Z [Term] id: FYPO:0004625 name: abnormal post-anaphase microtubule array organization def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which post-anaphase microtubule array organization is abnormal. Post-anaphase microtubule array organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of the post-anaphase microtubule array." [PMID:1904186, PomBase:mah] comment: Note that an abnormal post-anaphase microtubule array organization process may, but does not necessarily, result in abnormal post-anaphase microtubule array structure. synonym: "abnormal PAA organization" EXACT [GO:1904186] synonym: "abnormal post-anaphase array organization" EXACT [GO:1904186] synonym: "abnormal post-anaphase microtubule array organisation" EXACT [PomBase:mah] synonym: "abnormal post-anaphase microtubule array organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal post-anaphase microtubule array organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2015-05-05T15:38:26Z [Term] id: FYPO:0004626 name: inviable curved elongated mononucleate vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, is curved along the long axis, and contains one nucleus. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] synonym: "inviable curved elongated mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable curved elongated mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; curved elongated mononucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002411 ! inviable curved elongated vegetative cell is_a: FYPO:0004255 ! inviable elongated mononucleate vegetative cell created_by: midori creation_date: 2015-05-05T17:43:34Z [Term] id: FYPO:0004627 name: inviable after spore germination, multiple cell divisions, chromosome fragmentation upon segregation def: "A phenotype in which a spore germinates to produce a cell that undergoes two or more rounds of cell division during which chromosomes are broken during mitotic chromosome segregation, and then dies." [PMID:10572171, PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, chromosome fragmentation upon segregation" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, chromosome fragmentation upon segregation" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, chromosome fragmentation upon segregation" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2015-05-06T14:14:53Z [Term] id: FYPO:0004628 name: delayed onset of premeiotic DNA replication def: "A cellular process phenotype in which premeiotic DNA replication begins later than normal." [PomBase:mah] synonym: "delayed premeiotic DNA replication" EXACT [PomBase:mah] is_a: FYPO:0000625 ! abnormal premeiotic DNA replication created_by: midori creation_date: 2015-05-06T14:17:00Z [Term] id: FYPO:0004629 name: normal mitotic DNA replication def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic DNA replication is normal." [PomBase:mah] synonym: "normal DNA replication during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal DNA replication during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001133 ! normal DNA replication created_by: midori creation_date: 2015-05-06T14:18:54Z [Term] id: FYPO:0004630 name: decreased RNA level during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcript level during meiotic cell cycle" EXACT [PomBase:vw] synonym: "reduced RNA level during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2015-05-06T14:26:55Z [Term] id: FYPO:0004631 name: decreased protein level during meiotic anaphase I def: "A cell phenotype in which the amount of protein measured in a cell during anaphase of the first meiotic nuclear division is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during meiotic anaphase I" RELATED [PomBase:mah] synonym: "decreased protein level during anaphase of first meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein level during meiotic anaphase I" EXACT [PomBase:mah] is_a: FYPO:0004938 ! decreased protein level during meiosis I created_by: midori creation_date: 2015-05-06T16:23:38Z [Term] id: FYPO:0004632 name: decreased protein level during meiosis II def: "A cell phenotype in which the amount of protein measured in a cell during the second meiotic nuclear division is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during meiosis II" RELATED [PomBase:mah] synonym: "decreased protein level during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein level during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2015-05-06T16:25:03Z [Term] id: FYPO:0004633 name: decreased protein kinase activity during meiosis II def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the second meiotic nuclear division." [PomBase:mah] synonym: "decreased protein kinase activity during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein kinase activity during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2015-05-06T16:26:26Z [Term] id: FYPO:0004634 name: normal protein level during meiosis def: "A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein level during meiosis" EXACT [PomBase:mah] synonym: "normal protein accumulation during meiosis" RELATED [PomBase:mah] synonym: "normal protein level during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004083 ! normal protein level created_by: midori creation_date: 2015-05-06T16:28:14Z [Term] id: FYPO:0004635 name: increased protein localization to mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to mitotic spindle" EXACT [PomBase:mah] synonym: "increased protein localization to mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to spindle during mitosis" EXACT [PomBase:mah] synonym: "increased protein localization to spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2015-05-06T16:38:04Z [Term] id: FYPO:0004637 name: normal DNA-directed DNA polymerase activity def: "A molecular function phenotype in which the observed rate and other catalytic properties of a DNA-directed DNA polymerase activity are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal DNA polymerase activity" BROAD [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-05-08T12:04:03Z [Term] id: FYPO:0004638 name: abnormal cellular physical quality phenotype def: "A phenotype in which any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal cellular physical object quality" EXACT [PATO:0001241] is_a: FYPO:0000136 ! cellular physical quality phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2015-05-08T14:33:25Z [Term] id: FYPO:0004639 name: abnormal cellular physical quality phenotype during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal cellular physical object quality during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular physical quality phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2015-05-08T15:13:46Z [Term] id: FYPO:0004640 name: abnormal CAAX-protein geranylgeranyltransferase activity def: "A molecular function phenotype in which the observed rate of CAAX-protein geranylgeranyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-05-11T15:55:06Z [Term] id: FYPO:0004641 name: decreased CAAX-protein geranylgeranyltransferase activity def: "A molecular function phenotype in which the observed rate of CAAX-protein geranylgeranyltransferase activity is decreased." [PomBase:mah] synonym: "reduced CAAX-protein geranylgeranyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004640 ! abnormal CAAX-protein geranylgeranyltransferase activity created_by: midori creation_date: 2015-05-11T15:55:13Z [Term] id: FYPO:0004642 name: normal protein farnesyltransferase activity def: "A molecular function phenotype in which the observed rate of a protein farnesyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-05-11T15:56:44Z [Term] id: FYPO:0004643 name: normal Rab geranylgeranyltransferase activity def: "A molecular function phenotype in which the observed rate of Rab geranylgeranyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-05-11T15:57:27Z [Term] id: FYPO:0004644 name: abnormal bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity def: "A molecular function phenotype in which the observed rate of bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-05-11T15:59:47Z [Term] id: FYPO:0004645 name: increased bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity def: "A molecular function phenotype in which the observed rate of bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004644 ! abnormal bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity created_by: midori creation_date: 2015-05-11T15:59:52Z [Term] id: FYPO:0004646 name: normal duration of mitotic anaphase def: "A cell cycle phenotype in which the duration of anaphase of mitosis normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of anaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal duration of anaphase of mitosis" RELATED [PomBase:mah] synonym: "normal duration of mitotic anaphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2015-05-11T16:17:31Z [Term] id: FYPO:0004647 name: increased RNA level during cellular response to copper ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ions is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation during cellular response to copper ion" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to copper" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to copper ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to copper ion during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to copper ion" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-05-12T16:26:01Z [Term] id: FYPO:0004648 name: delayed onset of mitotic spindle assembly def: "A cellular process phenotype in which assembly of the mitotic spindle begins later than normal." [GO:0090307, PomBase:mah] synonym: "delayed mitotic spindle assembly" EXACT [PomBase:mah] synonym: "delayed onset of abnormal mitotic spindle assembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of bipolar mitotic spindle formation" EXACT [PomBase:al] synonym: "delayed onset of spindle assembly during mitotic cell cycle" EXACT [PomBase:mah] synonym: "delayed onset of spindle assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000177 ! abnormal mitotic spindle assembly created_by: midori creation_date: 2015-05-27T14:25:46Z [Term] id: FYPO:0004649 name: abolished protein localization to mitotic spindle pole body during metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body during metaphase does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle pole body during metaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein absent from mitotic spindle pole body during metaphase" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle pole body abolished during metaphase" EXACT [PomBase:mah] synonym: "protein localization to mitotic SPB abolished during metaphase" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle pole body abolished during metaphase" EXACT [PomBase:mah] synonym: "protein localization to spindle pole body abolished during metaphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006825 ! abolished protein localization to mitotic spindle pole body during mitosis created_by: midori creation_date: 2015-05-27T14:40:16Z [Term] id: FYPO:0004650 name: decreased mitotic spindle microtubule depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule in the mitotic spindle, occurs to a lesser extent than normal." [PomBase:mah] synonym: "decreased mitotic spindle microtubule catastrophe" RELATED [PomBase:mah] synonym: "decreased mitotic spindle microtubule depolymerisation" EXACT [PomBase:mah] synonym: "decreased mitotic spindle microtubule depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic spindle microtubule shrinkage" RELATED [Pombase:vw] synonym: "decreased spindle microtubule depolymerization during mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced mitotic spindle microtubule depolymerization" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth created_by: midori creation_date: 2015-05-27T14:42:39Z [Term] id: FYPO:0004651 name: decreased secondary cell septum thickness def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thinner than normal." [PomBase:mah] synonym: "decreased secondary cell septum thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased secondary cell septum thickness during vegetative growth" EXACT [PomBase:mah] synonym: "decreased secondary septum thickness" EXACT [PomBase:mah] synonym: "reduced secondary cell septum thickness" EXACT [PomBase:mah] synonym: "thin secondary septum" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth relationship: output_of FYPO:0003211 ! abnormal secondary cell septum biogenesis created_by: midori creation_date: 2015-05-27T15:47:50Z [Term] id: FYPO:0004652 name: normal actomyosin contractile ring morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the actomyosin contractile ring is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actomyosin contractile ring morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic contractile ring morphology" EXACT [PomBase:vw] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2015-05-27T15:52:51Z [Term] id: FYPO:0004653 name: delayed onset of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins later than normal." [PomBase:mah] synonym: "delayed actomyosin contractile ring contraction" EXACT [PomBase:mah] synonym: "delayed onset of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "delayed onset of mitotic contractile ring contraction" EXACT [PomBase:vw] synonym: "increased dwell time before actomyosin contractile ring contraction" EXACT [PomBase:mah] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2015-05-27T15:54:37Z [Term] id: FYPO:0004654 name: thin, incomplete secondary cell septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thinner than normal and does not extend over the entire cell division site." [PMID:25473118, PomBase:mah] synonym: "incomplete secondary cell septum with decreased thickness" EXACT [PomBase:mah] synonym: "incomplete secondary cell septum with reduced thickness" EXACT [PomBase:mah] synonym: "thin, discontinuous secondary septum" EXACT [PMID:25473118] synonym: "thin, incomplete secondary cell septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "thin, incomplete secondary cell septum during vegetative growth" EXACT [PomBase:mah] synonym: "thin, incomplete secondary septum" EXACT [PomBase:mah] is_a: FYPO:0004651 ! decreased secondary cell septum thickness is_a: FYPO:0005870 ! incomplete septum relationship: has_part FYPO:0004651 ! decreased secondary cell septum thickness created_by: midori creation_date: 2015-05-27T16:07:02Z [Term] id: FYPO:0004655 name: increased protein localization to cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell division site" EXACT [PomBase:mah] synonym: "increased protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein recruitment to cell division site" RELATED [PomBase:vw] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2015-05-27T16:15:46Z [Term] id: FYPO:0004656 name: increased protein localization to telomere during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "increased protein localisation to telomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromosome, telomeric region, during vegetative growth" EXACT [GO:0070198, PomBase:mah] synonym: "increased protein localization to telomere during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002840 ! increased protein localization to chromosome during vegetative growth is_a: FYPO:0003108 ! abnormal protein localization to telomere during vegetative growth created_by: midori creation_date: 2015-05-27T16:16:34Z [Term] id: FYPO:0004657 name: inviable mononucleate multiseptate vegetative cell alt_id: FYPO:0002001 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has one nucleus and more than one septum." [PomBase:mah] synonym: "cytokinesis in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "cytokinesis without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable mononucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable mononucleate multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; mononucleate multiseptate vegetative cell" EXACT [PomBase:mah] synonym: "mononucleate multiseptate vegetative cell" EXACT [PomBase:mah] synonym: "mononucleate multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "septation without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "vegetative cell with premature septation" RELATED [PomBase:al, PomBase:vw] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0006430 ! inviable mononucleate vegetative cell relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2015-05-27T16:23:27Z [Term] id: FYPO:0004658 name: inviable binucleate multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has two nuclei and more than one septum." [PomBase:mah] synonym: "inviable binucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable binucleate multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; binucleate multiseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001223 ! binucleate multiseptate vegetative cell is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2015-05-27T16:24:42Z [Term] id: FYPO:0004659 name: abolished protein phosphorylation during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-05-27T16:25:40Z [Term] id: FYPO:0004660 name: abolished protein phosphorylation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to methyl methanesulfonate." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to MMS" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-05-27T16:40:39Z [Term] id: FYPO:0004661 name: obsolete normal protein tyrosine phosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "normal protein tyrosine phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_obsolete: true replaced_by: FYPO:0000776 created_by: midori creation_date: 2015-05-27T16:42:15Z [Term] id: FYPO:0004662 name: normal viability following cellular response to UV def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to ultraviolet light." [PomBase:mah] synonym: "normal cell population viability following cellular response to UV" EXACT [PomBase:mah] synonym: "normal viability following cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal viability following UV exposure" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2015-05-27T16:44:03Z [Term] id: FYPO:0004663 name: normal viability following cellular response to methyl methanesulfonate def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to methyl methanesulfonate." [PomBase:mah] synonym: "normal cell population viability following cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal viability following cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal viability following cellular response to MMS" EXACT [PomBase:mah] synonym: "normal viability following MMS exposure" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2015-05-27T16:45:37Z [Term] id: FYPO:0004664 name: obsolete increased duration of protein tyrosine phosphorylation during cellular response to salt stress def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation on tyrosine residues is longer than normal during a cellular response to salt stress. All protein tyrosine phosphorylation may be affected, or tyrosine residues in one or more specific proteins, or at specific protein sites, or even specific sites within specific proteins." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased duration of protein tyrosine phosphorylation during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein tyrosine phosphorylation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein tyrosine phosphorylation during cellular response to salt stress" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004062 created_by: midori creation_date: 2015-05-27T17:11:02Z [Term] id: FYPO:0004665 name: linear elements absent from cell def: "A physical cellular phenotype in which linear elements are absent from the cell." [PomBase:mah] comment: In the absence of filamentous actin, a ring structure may form, but is not considered a contractile ring. synonym: "absent linear elements" EXACT [PomBase:al] synonym: "linear elements absent" EXACT [PomBase:mah] is_a: FYPO:0005986 ! linear elements present in decreased numbers created_by: midori creation_date: 2015-05-28T11:33:11Z [Term] id: FYPO:0004666 name: decreased meiotic sister chromatid cohesion along chromosome arms def: "A cellular process phenotype in which cohesion between sister chromatids is decreased along the length of the chromosome arms during meiosis." [PomBase:mah] synonym: "abnormal sister chromatid cohesion along chromosome arms during meiosis" EXACT [PomBase:mah] synonym: "decreased meiotic sister chromatid cohesion, arms" EXACT [GO:0051760] synonym: "reduced meiotic sister chromatid cohesion along chromosome arms" EXACT [PomBase:mah] is_a: FYPO:0002092 ! abnormal meiotic sister chromatid cohesion created_by: midori creation_date: 2015-05-28T11:36:49Z [Term] id: FYPO:0004667 name: normal meiotic sister chromatid cohesion at centromere def: "A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) at the centromeric regions during meiosis." [PomBase:mah] synonym: "normal meiotic sister chromatid cohesion, centromeric" EXACT [GO:0051754] synonym: "normal sister chromatid cohesion at centromere during meiosis" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2015-05-28T11:39:16Z [Term] id: FYPO:0004668 name: premature homologous chromosome segregation def: "A cellular process phenotype in which homologous chromosome segregation begins earlier than normal." [PomBase:mah] synonym: "advanced homologous chromosome segregation" EXACT [PomBase:mah] synonym: "premature chromosome segregation during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0004159 ! abnormal homologous chromosome segregation created_by: midori creation_date: 2015-05-28T11:47:12Z [Term] id: FYPO:0004669 name: sensitive to ferrozine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ferrozine. Cells stop growing (and may die) at a concentration of ferrozine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to ferrozine" EXACT [PomBase:mah] synonym: "sensitive to ferrozine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ferrozine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ferrozine(2-)" EXACT [CHEBI:63945] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-05-28T12:17:33Z [Term] id: FYPO:0004670 name: abnormal macroautophagy during nitrogen starvation def: "A cellular process phenotype in which macroautophagy is abnormal when the cell is subject to nitrogen starvation. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm." [GO:0016236, PomBase:mah] synonym: "abnormal macroautophagy during cellular response to nitrogen starvation" EXACT [] synonym: "abnormal macroautophagy during nitrogen depletion" EXACT [PomBase:mah] synonym: "abnormal macroautophagy during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal macroautophagy created_by: midori creation_date: 2015-05-28T12:26:18Z [Term] id: FYPO:0004671 name: abolished protein localization to vacuole during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the vacuole is abolished when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to vacuole during nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to vacuole during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to vacuole during nitrogen deprivation" EXACT [PomBase:mah] synonym: "protein localization to vacuole abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001375 ! abolished protein localization created_by: midori creation_date: 2015-05-28T12:29:17Z [Term] id: FYPO:0004672 name: inviable elongated vegetative cell with fragmented nucleus def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains a nucleus that is broken into small fragments." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002061) or one of its descendants. synonym: "elongated inviable cell with fragmented nucleus" EXACT [PomBase:mah] synonym: "inviable elongated cell with fragmented nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented DNA" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell with fragmented nucleus" EXACT [PomBase:mah] is_a: FYPO:0001490 ! inviable elongated vegetative cell is_a: FYPO:0001919 ! fragmented nucleus during vegetative growth created_by: midori creation_date: 2015-05-28T13:10:33Z [Term] id: FYPO:0004673 name: inviable elongated multiseptate vegetative cell with fragmented nucleus def: "A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, contains more than one septum, and contains a nucleus that is broken into small fragments." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002061) or one of its descendants. synonym: "elongated inviable multiseptate cell with fragmented nucleus" EXACT [PomBase:mah] synonym: "inviable elongated multiseptate cell with fragmented nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated multiseptate vegetative cell with fragmented DNA" RELATED [PomBase:mah] synonym: "inviable elongated multiseptate vegetative cell with fragmented nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated multiseptate vegetative cell with fragmented nucleus" EXACT [PomBase:mah] is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0006661 ! fragmented nucleus created_by: midori creation_date: 2015-05-28T13:16:02Z [Term] id: FYPO:0004674 name: sensitive to dimethyl sulfoxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to dimethyl sulfoxide. Cells stop growing (and may die) at a concentration of dimethyl sulfoxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to dimethyl sulfoxide" EXACT [PomBase:mah] synonym: "sensitive to dimethyl sulfoxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to dimethyl sulfoxide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to dimethyl sulphoxide" EXACT [PomBase:mah] synonym: "sensitive to DMSO" EXACT [CHEBI:28262, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-05-28T13:23:24Z [Term] id: FYPO:0004675 name: normal growth on dimethyl sulfoxide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing dimethyl sulfoxide." [PomBase:mah] synonym: "normal cell population growth in presence of dimethyl sulfoxide" EXACT [PomBase:mah] synonym: "normal cell population growth on dimethyl sulfoxide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on DMSO" EXACT [CHEBI:28262] synonym: "normal cellular response to dimethyl sulfoxide" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on dimethyl sulphoxide" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on dimethyl sulfoxide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-05-28T13:25:59Z [Term] id: FYPO:0004676 name: abnormal purine-specific mismatch base pair DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of purine-specific mismatch base pair DNA N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: midori creation_date: 2015-05-28T13:33:44Z [Term] id: FYPO:0004677 name: abolished purine-specific mismatch base pair DNA N-glycosylase activity def: "A molecular function phenotype in which purine-specific mismatch base pair DNA N-glycosylase activity is absent." [PomBase:mah] synonym: "purine-specific mismatch base pair DNA N-glycosylase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004676 ! abnormal purine-specific mismatch base pair DNA N-glycosylase activity created_by: midori creation_date: 2015-05-28T13:33:58Z [Term] id: FYPO:0004678 name: increased polyadenylated 25S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature, polyadenylated 25S rRNA measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mature polyadenylated 25S rRNA transcript level" EXACT [PomBase:vw] synonym: "increased polyadenylated 25S rRNA accumulation" RELATED [PomBase:mah] synonym: "increased polyadenylated 25S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased polyadenylated 25S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased polyadenylated 25S rRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0008091 ! increased polyadenylated rRNA level created_by: midori creation_date: 2015-05-28T13:51:41Z [Term] id: FYPO:0004679 name: polyadenylated 25S rRNA absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated 25S rRNA measured in a cell is too low to detect." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "polyadenylated 25S rRNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "polyadenylated 25S rRNA absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "polyadenylated 25S rRNA transcripts absent from cell during vegetative growth" EXACT [PomBase:vw] synonym: "undetectable polyadenylated 25S rRNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: midori creation_date: 2015-05-28T13:55:12Z [Term] id: FYPO:0004680 name: normal polyadenylated 5.8S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated 5.8S rRNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal polyadenylated 5.8S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal polyadenylated 5.8S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal polyadenylated 5.8S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal polyadenylated 5.8S rRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2015-05-28T14:19:07Z [Term] id: FYPO:0004681 name: decreased polyadenylated 5.8S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature polyadenylated 5.8S rRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 5.8S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature polyadenylated 5.8S rRNA transcript level" EXACT [PomBase:vw] synonym: "decreased polyadenylated 5.8S rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased polyadenylated 5.8S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased polyadenylated 5.8S rRNA transcript level" EXACT [PomBase:vw] synonym: "reduced polyadenylated 5.8S rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001138 ! decreased mature 5.8S rRNA level created_by: midori creation_date: 2015-05-28T14:20:04Z [Term] id: FYPO:0004682 name: normal polyadenylated 5S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated 5S rRNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal polyadenylated 5S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal polyadenylated 5S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal polyadenylated 5S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal polyadenylated 5S rRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2015-05-28T14:21:38Z [Term] id: FYPO:0004683 name: unequal nucleolus inheritance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the nucleolus is partitioned to daughter cells unequally during cell division." [PMID:16478992, PMID:1661641, PomBase:mah] synonym: "unequal mitotic nucleolar partitioning" EXACT [PomBase:al] synonym: "unequal mitotic nucleolar segregation" EXACT [PomBase:al] synonym: "unequal nucleolar inheritance" EXACT [PomBase:mah] synonym: "unequal nucleolus distribution" EXACT [PomBase:mah] synonym: "unequal nucleolus inheritance during mitotic cell cycle" RELATED [PomBase:mah] synonym: "unequal nucleolus inheritance during vegetative growth" EXACT [PomBase:mah] synonym: "unequal nucleolus partitioning" EXACT [PomBase:mah] synonym: "unequal nucleolus segregation" EXACT [PomBase:mah] synonym: "unequal rDNA segregation" RELATED [PomBase:vw] is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2015-05-28T14:22:40Z [Term] id: FYPO:0004684 name: inviable elongated binucleate aseptate cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is elongated, and has two nuclei but no septum." [PomBase:mah] comment: This phenotype may indicate that the cytokinesis after mitosis checkpoint is activated. synonym: "inviable elongated binucleate aseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated binucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated binucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "lethal; elongated binucleate aseptate cell" EXACT [PomBase:mah] is_a: FYPO:0002024 ! inviable elongated multinucleate aseptate vegetative cell is_a: FYPO:0004562 ! binucleate aseptate vegetative cell created_by: midori creation_date: 2015-06-02T13:22:25Z [Term] id: FYPO:0004685 name: sensitive to radicicol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to radicicol. Cells stop growing (and may die) at a concentration of radicicol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to radicicol" EXACT [PomBase:mah] synonym: "sensitive to radicicol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to radicicol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-06-08T13:48:45Z [Term] id: FYPO:0004686 name: sensitive to streptothricin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to streptothricin. Cells stop growing (and may die) at a concentration of streptothricin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to streptothricin" EXACT [PomBase:mah] synonym: "sensitive to streptothricin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to streptothricin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-06-08T13:50:14Z [Term] id: FYPO:0004687 name: sensitive to lovastatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lovastatin. Cells stop growing (and may die) at a concentration of lovastatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to lovastatin" EXACT [PomBase:mah] synonym: "sensitive to lovastatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to lovastatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-06-08T13:50:58Z [Term] id: FYPO:0004688 name: decreased cytosolic large ribosomal subunit level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer free large ribosomal subunits in the cytosol than normal." [PomBase:mah] synonym: "cytosolic large ribosomal subunit present at decreased level" EXACT [PomBase:mah] synonym: "decreased 60S ribosomal subunit level" EXACT [PomBase:mah] synonym: "decreased cytosolic large ribosomal subunit level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytosolic large ribosomal subunit level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased large ribosomal subunit level" BROAD [PomBase:mah] synonym: "decreased level of cytosolic large ribosomal subunits" RELATED [PomBase:al] synonym: "reduced cytosolic large ribosomal subunit level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-06-08T13:59:13Z [Term] id: FYPO:0004689 name: increased cenH-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from cenH measured in a cell is higher than normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs." [PMID:21253571, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "accumulation of cenH-derived RNA transcripts" RELATED [PomBase:vw] synonym: "increased cenH RNA level" EXACT [PomBase:al] synonym: "increased cenH-derived RNA accumulation" RELATED [PomBase:mah] synonym: "increased cenH-derived RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cenH-derived RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cenH-derived RNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0004982 ! increased centromeric transcript level created_by: midori creation_date: 2015-06-09T10:59:17Z [Term] id: FYPO:0004690 name: increased histone H3-K9 acetylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 at the silent mating-type cassettes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K9 acetylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 acetylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 acetylation at silent mating-type cassette during vegetative growth" EXACT [GO:0043970, PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2015-06-09T11:01:24Z [Term] id: FYPO:0004691 name: inviable swollen spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a sphere, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "inviable enlarged spherical vegetative cell" RELATED [PomBase:mah] synonym: "inviable enlarged volume spherical vegetative cell" EXACT [PomBase:mah] synonym: "inviable large spherical vegetative cell" RELATED [PomBase:vw] synonym: "inviable swollen spherical cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen spherical vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable, increased spherical vegetative cell size" RELATED [PomBase:vw] synonym: "inviable, increased spherical vegetative cell volume" EXACT [PomBase:mah] synonym: "lethal; swollen spherical vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000947 ! swollen spherical vegetative cell is_a: FYPO:0002190 ! inviable swollen spheroid vegetative cell is_a: FYPO:0004104 ! inviable spherical vegetative cell created_by: midori creation_date: 2015-06-09T11:16:29Z [Term] id: FYPO:0004692 name: normal protein localization to mitotic spindle midzone def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle midzone" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle midzone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to mitotic spindle midzone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0007865 ! normal protein localization to spindle created_by: midori creation_date: 2015-06-09T11:32:39Z [Term] id: FYPO:0004693 name: normal viability following cellular response to hydroxyurea def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to hydroxyurea." [PomBase:mah] synonym: "normal cell population viability following cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal viability following cellular response to HU" EXACT [PomBase:mah] synonym: "normal viability following HU exposure" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2015-06-09T15:08:04Z [Term] id: FYPO:0004694 name: fragmented DNA during stationary phase def: "A cell phenotype in which DNA is broken into small fragments when the population in which the cell is found is in stationary phase." [PMID:12963726, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. Use 'fragmented DNA' (FYPO:0000160) or one of its descendants if DNA was detected using a method that can resolve molecule sizes (e.g. gel electrophoresis) or detect DNA ends (e.g. TUNEL assay). Otherwise, consider using 'fragmented nucleus' (FYPO:0001919) or one of its descendants. synonym: "DNA fragmentation during stationary phase" EXACT [PomBase:mah] synonym: "fragmented nucleus during stationary phase" RELATED [PomBase:mah] is_a: FYPO:0000160 ! fragmented DNA created_by: midori creation_date: 2015-06-12T13:45:52Z [Term] id: FYPO:0004695 name: increased cellular diglyceride level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more diglycerides measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular DAG level" EXACT [PomBase:mah] synonym: "increased cellular diacylglycerol level" EXACT [CHEBI:18035] synonym: "increased cellular diglyceride level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular diglyceride level during vegetative growth" EXACT [PomBase:mah] synonym: "increased diglyceride accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2015-06-12T13:52:54Z [Term] id: FYPO:0004696 name: sensitive to fatty acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more fatty acids (usually supplied as the corresponding anions). Cells stop growing (and may die) at a concentration of fatty acid that allows wild type cells to grow." [PMID:12963726, PomBase:mah] synonym: "hypersensitive to fatty acid" EXACT [PomBase:mah] synonym: "sensitive to fatty acid anion" EXACT [CHEBI:28868, CHEBI:35366] synonym: "sensitive to fatty acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to fatty acid during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to free fatty acids" EXACT [PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-06-12T14:33:27Z [Term] id: FYPO:0004697 name: sensitive to 1,2-dioctanoyl-sn-glycerol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,2-dioctanoyl-sn-glycerol (DiC8 DAG). Cells stop growing (and may die) at a concentration of 1,2-dioctanoyl-sn-glycerol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 1,2-dioctanoyl-sn-glycerol" EXACT [PomBase:mah] synonym: "sensitive to 1,2-dioctanoyl-sn-glycerol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 1,2-dioctanoyl-sn-glycerol during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DiC8 DAG" EXACT [PMID:12963726] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-06-12T14:54:29Z [Term] id: FYPO:0004698 name: decreased heme binding def: "A molecular function phenotype in which occurrence of heme binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds heme less than wild type, or that a mutation in one gene decreases heme binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "decreased haem binding" EXACT [PomBase:mah] synonym: "reduced heme binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2015-06-12T15:05:16Z [Term] id: FYPO:0004700 name: bent vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is bent along the long axis. In a bent cell, the long axis has one or more angles, rather than following a straight line." [PomBase:mah] synonym: "bent cell during vegetative growth" EXACT [PomBase:mah] synonym: "bent vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell morphology, bent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape is_a: FYPO:0005793 ! bent cell created_by: midori creation_date: 2015-07-08T16:24:25Z [Term] id: FYPO:0004701 name: abolished cell division timing change upon nitrogen source shift def: "A phenotype in which a cell does not alter the timing or rate of cell division when shifted from one nitrogen source to another. Normally, cell division is delayed upon shifting from a poor to a rich nitrogen source, and accelerated upon shifting from a rich to a poor nitrogen source." [PMID:689088, PMID:872891, PomBase:mah] comment: This phenotype is typically observed at the population level. Good (or rich) nitrogen sources are distinguished from poor sources based on how readily nitrogen is assimilated into cellular metabolism. In microorganisms, good nitrogen sources generally support higher cell population growth rates than poor sources. In fission yeast, cells divide at a smaller size when grown on a poor nitrogen source than in nitrogen-rich media; proline is commonly used as a poor nitrogen source. synonym: "abolished cell division rate change upon nitrogen source shift" RELATED [PomBase:mah] synonym: "abolished change in cell division rate upon nitrogen source shift" RELATED [PomBase:mah] synonym: "abolished change in cell division timing upon nitrogen source shift" EXACT [PomBase:mah] synonym: "abolished nutritional modulation of cell division" RELATED [PomBase:mah] synonym: "unchanged cell division timing upon nitrogen source shift" RELATED [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2015-07-10T14:37:09Z [Term] id: FYPO:0004702 name: cytoplasmic microtubules absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable cytoplasmic microtubules." [PomBase:mah] synonym: "absent cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubules absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002004 ! microtubules absent from cell created_by: midori creation_date: 2015-07-10T14:49:27Z [Term] id: FYPO:0004703 name: viable curved, elongated, swollen vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable, is longer and has a larger volume than normal, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved elongated swollen viable cell" EXACT [PomBase:mah] synonym: "viable curved swollen elongated cell" EXACT [PomBase:mah] synonym: "viable curved, elongated, swollen cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved, elongated, swollen vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002215 ! viable curved elongated vegetative cell is_a: FYPO:0002402 ! viable swollen vegetative cell with abnormal cell shape is_a: FYPO:0002479 ! viable swollen elongated vegetative cell created_by: midori creation_date: 2015-07-10T15:04:39Z [Term] id: FYPO:0004704 name: interphase microtubules present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic microtubules than normal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "cytoplasmic microtubules present in greater numbers" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules present in increased numbers during mitotic interphase" EXACT [PomBase:mah] synonym: "increased level of interphase MTs" EXACT [PomBase:mah] synonym: "interphase cytoplasmic microtubules present in increased numbers" EXACT [PomBase:mah] synonym: "interphase microtubules present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "interphase microtubules present in increased numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002399 ! abnormal microtubule cytoskeleton created_by: midori creation_date: 2015-07-10T15:07:06Z [Term] id: FYPO:0004705 name: delayed onset of mitotic sister chromatid separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation begins later than normal." [PomBase:mah] synonym: "delayed mitotic sister chromatid separation" EXACT [PomBase:mah] synonym: "delayed onset of mitotic sister chromatid separation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of sister chromatid separation during mitosis" EXACT [PomBase:mah] synonym: "delayed onset of sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2015-07-10T15:10:03Z [Term] id: FYPO:0004706 name: decreased cytosolic monomeric ribosome level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer monomeric ribosomes (80S monosomes) in the cytosol than normal." [PMID:26122634, PomBase:mah] synonym: "cytosolic monomeric ribosomes present at decreased level" EXACT [PomBase:mah] synonym: "decreased cytosolic 80S monosome level" EXACT [PomBase:mah] synonym: "decreased cytosolic monomeric 80S ribosome level" EXACT [PomBase:mah] synonym: "decreased cytosolic monomeric ribosome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytosolic monomeric ribosome level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cytosolic ribosome level" BROAD [PomBase:mah] synonym: "decreased level of cytosolic monomeric ribosomes" EXACT [PomBase:al] synonym: "reduced cytosolic monomeric ribosome level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2015-07-10T15:17:13Z [Term] id: FYPO:0004707 name: increased cytosolic half-mer polysome level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more half-mer polysomes in the cytosol than normal. A half-mer polysome is a complex consisting of an mRNA bound to a single small ribosomal subunit, followed by one or more complete bound ribosomes." [PMID:18611858, PMID:19806183, PMID:26122634, PomBase:mah] synonym: "cytosolic half-mer polysomes present at increased level" EXACT [PomBase:mah] synonym: "increased cytosolic half-mer polysome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cytosolic half-mer polysome level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cytosolic halfmer polysome level" EXACT [PomBase:mah] synonym: "increased level of cytosolic half-mer polysomes" RELATED [PomBase:al] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2015-07-10T15:20:10Z [Term] id: FYPO:0004708 name: decreased cytosolic large:small ribosomal subunit ratio def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the ratio of large to small ribosomal subunits present in the cytosol is lower than normal.." [PMID:26122634, PomBase:mah] synonym: "decreased 60S:40S cytosolic ribosomal subunit ratio" EXACT [PomBase:mah] synonym: "decreased cytosolic 60S:40S ribosomal subunit ratio" EXACT [PomBase:mah] synonym: "decreased cytosolic large:small ribosomal subunit ratio during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytosolic large:small ribosomal subunit ratio during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cytosolic ribosomal large:small subunit ratio" EXACT [PomBase:mah] synonym: "reduced cytosolic large:small ribosomal subunit ratio" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2015-07-10T15:23:17Z [Term] id: FYPO:0004709 name: increased number of Rad52 foci def: "A cell phenotype in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal." [PMID:22064477, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2015-07-14T11:51:29Z [Term] id: FYPO:0004710 name: increased number of Rad52 foci during G0 to G1 transition def: "A cell phenotype observed when the cell undergoes transition from G0 phase to G1 in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal." [PMID:19197239, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during G0 to G1 transition" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cell cycle re-entry" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during exit from cell quiescence" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during recovery from quiescence" EXACT [PomBase:vw] is_a: FYPO:0004709 ! increased number of Rad52 foci created_by: midori creation_date: 2015-07-14T12:03:46Z [Term] id: FYPO:0004711 name: decreased level of translation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more translation RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Translation RNAs are transcribed from genes whose products are involved in translation." [PMID:18203864, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of translation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of translation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of translation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased translation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of translation gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005858 ! altered level of translation gene mRNA during vegetative growth created_by: midori creation_date: 2015-07-15T15:27:26Z [Term] id: FYPO:0004712 name: decreased level of nucleotide metabolism gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more nucleotide metabolism RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Nucleotide metabolism RNAs are transcribed from genes whose products are involved in any nucleotide metabolic process." [PMID:18203864, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of nucleotide metabolism gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of nucleotide metabolism gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of nucleotide metabolism gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased nucleotide metabolism gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of nucleotide metabolism gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-07-15T15:29:26Z [Term] id: FYPO:0004713 name: decreased level of amino acid biosynthesis gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid biosynthesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Amino acid biosynthesis RNAs are transcribed from genes whose products are involved in amino acid biosynthetic processes." [PMID:18203864, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased amino acid biosynthesis gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of amino acid biosynthesis gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of amino acid biosynthesis gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of amino acid biosynthesis gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of amino acid biosynthesis gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-07-15T15:45:30Z [Term] id: FYPO:0004714 name: decreased level of amino acid import gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid import RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Amino acid import RNAs are transcribed from genes whose products are involved in amino acid import into the cell or an organelle." [PMID:18203864, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased amino acid import gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of amino acid import gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of amino acid import gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of amino acid import gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of amino acid import gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-07-15T15:46:19Z [Term] id: FYPO:0004715 name: large vacuoles present in decreased numbers during salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, vacuoles than normal when the cell is subject to salt stress." [PomBase:mah] synonym: "enlarged vacuoles present in decreased numbers during salt stress" EXACT [PomBase:mah] synonym: "large vacuoles present in decreased numbers during salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large vacuoles present in decreased numbers during salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "large vacuoles present in reduced numbers during salt stress" EXACT [PomBase:mah] is_a: FYPO:0002795 ! large vacuoles present in decreased numbers during vegetative growth created_by: midori creation_date: 2015-07-15T15:49:58Z [Term] id: FYPO:0004716 name: decreased protein localization to subtelomeric heterochromatin during horsetail movement def: "A cell phenotype in which the localization of a protein to heterochromatin at subtelomeres is decreased during the part of meiotic prophase I in which horsetail nuclear movement takes place." [PMID:11676925, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to heterochromatin at subtelomere during horsetail movement" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at subtelomere during horsetail movement" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at subtelomere during horsetail nuclear movement" EXACT [GO:0030989] synonym: "decreased protein localization to subtelomeric heterochromatin during dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989] synonym: "decreased protein localization to subtelomeric heterochromatin during meiotic horsetail phase" RELATED [PomBase:al] synonym: "decreased protein localization to telomeric heterochromatin during horsetail movement" RELATED [PomBase:mah, PomBase:vw] synonym: "reduced protein localization to heterochromatin at subtelomere during horsetail movement" EXACT [PomBase:mah] is_a: FYPO:0002957 ! abnormal protein localization to nucleus during meiosis is_a: FYPO:0004717 ! abnormal protein localization to heterochromatin during meiosis is_a: FYPO:0005576 ! decreased protein localization to chromatin during meiotic cell cycle is_a: FYPO:0005918 ! decreased protein localization to subtelomeric heterochromatin created_by: midori creation_date: 2015-07-20T15:28:12Z [Term] id: FYPO:0004717 name: abnormal protein localization to heterochromatin during meiosis def: "A cell phenotype in which the localization of a protein to heterochromatin is abnormal during the meiotic cell cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to heterochromatin during meiosis" EXACT [PomBase:mah] synonym: "abnormal protein localization to heterochromatin during meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0004718 ! abnormal protein localization to heterochromatin created_by: midori creation_date: 2015-07-20T15:30:34Z [Term] id: FYPO:0004718 name: abnormal protein localization to heterochromatin def: "A cell phenotype in which the localization of a protein to heterochromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2015-07-20T15:32:11Z [Term] id: FYPO:0004719 name: abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have condensed chromosomes and a single, normally located septum, under conditions where arrest does not normally occur." [PMID:8387358, PomBase:al, PomBase:mah] comment: In wild-type cells, chromosomes are condensed only in M phase. This term can be used for mutants in which chromosomes are condensed but other normal features of M phase cells are not observed. synonym: "abnormal cell cycle arrest with condensed chromosomes, septated cell during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest with condensed chromosomes, septated vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0003738 ! abnormal mitotic cell cycle arrest with condensed chromosomes created_by: midori creation_date: 2015-07-20T16:00:02Z [Term] id: FYPO:0004720 name: normal viability following cellular response to heat shock def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PMID:11711540, PomBase:mah] synonym: "normal cell population viability following heat shock" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2015-07-20T16:10:01Z [Term] id: FYPO:0004721 name: obsolete decreased rate of microtubule depolymerization at minus end def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which minus-end specific microtubule depolymerization, i.e. the removal of tubulin dimers from the minus end of a microtubule, occurs at a lower rate, or speed, than normal." [GO:0036078, PomBase:mah] comment: In wild-type cells, microtubule minus ends are capped by the gamma-tubulin complex (they are not dynamic, they don't grow or shrink), so the minus end depolymerisation speed of the wild type in normal conditions cannot be measured and compared. It is possible to measure shrinkage speeds of minus ends in wild-type cells, specifically using laser ablation (cutting microtubules). This leads to minus end depolymerisation. It could be that in a certain study this minus end depolymerisation is compared in two genetic backgrounds. In that case, however, the phenotype could specify "after laser ablation". synonym: "decreased microtubule depolymerization rate at minus end" EXACT [PomBase:mah] synonym: "decreased microtubule minus end shrinkage" RELATED [PomBase:vw] synonym: "decreased rate of microtubule catastrophe at minus end" RELATED [PomBase:mah] synonym: "decreased rate of microtubule depolymerisation at minus end" EXACT [PomBase:mah] synonym: "decreased rate of microtubule depolymerization at minus end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of microtubule depolymerization at minus end during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of minus-end specific microtubule depolymerization" EXACT [GO:0036078] synonym: "increased microtubule stability" RELATED [PomBase:vw] synonym: "reduced rate of microtubule depolymerization at minus end" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0008006 created_by: midori creation_date: 2015-07-27T11:56:31Z [Term] id: FYPO:0004722 name: normal nuclear microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the morphology of nuclear microtubules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal nuclear microtubule morphology" EXACT [PomBase:al] synonym: "normal nuclear microtubule structure" NARROW [PomBase:mah] synonym: "normal nuclear microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2015-07-27T12:06:15Z [Term] id: FYPO:0004723 name: transiently misoriented mitotic spindle def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle is assembled in an incorrect orientation. Spindle orientation is later corrected so that the spindle is parallel to the long axis of the cell." [PMID:15772152, PomBase:mah] comment: In wild-type cells, the spindle is initially misoriented in a small number of cells (typically around 8% of a cell population). Use this term if the frequency of spindle misorientation is increased above the wild-type occurrence. synonym: "transient abnormal mitotic spindle orientation" EXACT [PomBase:mah] synonym: "transient mitotic spindle misorientation" EXACT [PomBase:mah] synonym: "transiently misoriented mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "transiently misoriented spindle during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0007388 ! misoriented mitotic spindle created_by: midori creation_date: 2015-07-27T12:29:27Z [Term] id: FYPO:0004724 name: long nuclear microtubules protruding through nuclear envelope during interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form nuclear microtubules during interphase of the mitotic cell cycle that are longer than normal, and are partially or completely surrounded by an extension of the nuclear envelope. These microtubules usually have one end in close proximity to a spindle pole body, and may puncture the nuclear envelope to extent into the cytoplasm." [PMID:15772152, PomBase:mah] synonym: "long nuclear microtubules during interphase, with nuclear envelope deformation" RELATED [PomBase:vw] synonym: "long nuclear microtubules during interphase, with nuclear envelope protrusion" EXACT [PomBase:vw] synonym: "long nuclear microtubules protruding through nuclear envelope at interphase" EXACT [PomBase:vw] synonym: "long nuclear microtubules protruding through nuclear envelope during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long nuclear microtubules protruding through nuclear envelope during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "long nuclear microtubules protruding through nuclear envelope during mitotic interphase" EXACT [PomBase:vw] synonym: "nuclear envelope protrusion with long mitotic spindle microtubules protruding beyond SPB during interphase" EXACT [PomBase:mah] synonym: "nuclear envelope protrusion with long mitotic spindle microtubules protruding beyond SPB during interphase" EXACT [PomBase:vw] synonym: "nuclear envelope protrusion with long mitotic spindle microtubules protruding beyond spindle pole body during interphase" EXACT [PomBase:vw] is_a: FYPO:0000055 ! long microtubules is_a: FYPO:0004725 ! nuclear envelope protrusion present during mitotic interphase relationship: has_part FYPO:0004725 ! nuclear envelope protrusion present during mitotic interphase created_by: midori creation_date: 2015-07-27T12:51:58Z [Term] id: FYPO:0004725 name: nuclear envelope protrusion present during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has one or more extensions that protrude into the cytoplasm during interphase of the mitotic cell cycle." [PMID:15772152, PomBase:mah] comment: This term differs from 'lobate nuclear envelope' (FYPO:0002005) in that a lobate envelope has a few deep fissures extending inward from the cytoplasm that appear to partially divide the nucleus into portions, whereas protrusions are smaller and extend outward from the bulk of the nucleus. synonym: "nuclear envelope deformation during mitotic interphase" RELATED [Pombase:vw] synonym: "nuclear envelope protrusion present during interphase" EXACT [PomBase:mah] synonym: "nuclear envelope protrusion present during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear envelope protrusion present during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protruding nuclear envelope during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2015-07-27T12:52:58Z [Term] id: FYPO:0004726 name: normal mitotic spindle orientation correction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle orientation correction is normal (i.e. indistinguishable from wild type). Spindle orientation correction is the process by which a spindle that has formed in, or moved into, an incorrect orientation is restored to the correct orientation (parallel to the long axis of the cell)." [PMID:15772152, PomBase:mah] comment: The mitotic spindle may form in an incorrect orientation infrequently in wild-type cells, or at a higher frequency in some mutants. Use this term for mutants in which the process of correcting the orientation of a misoriented spindle is the same as wild type, even if the initial misorientation occurs more frequently than in wild type. synonym: "normal correction of mitotic spindle orientation" EXACT [PomBase:mah] synonym: "normal mitotic spindle orientation correction during vegetative growth" EXACT [PomBase:mah] synonym: "normal repair of mitotic mono-orientation defect" EXACT [GO:1990598] synonym: "normal spindle orientation correction during mitosis" EXACT [PomBase:mah] synonym: "normal spindle orientation correction during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-07-27T13:11:51Z [Term] id: FYPO:0004727 name: cytoplasmic microtubule formation from nuclear microtubules def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules are formed from existing nuclear microtubules. Normally, cytoplasmic microtubules are nucleated from microtubule organizing centers in the cytoplasm." [PMID:15772152, PomBase:mah] synonym: "cytoplasmic microtubule formation from nuclear microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubule formation from nuclear microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2015-07-27T13:32:05Z [Term] id: FYPO:0004728 name: cytoplasmic microtubule formation from nuclear microtubules following nuclear envelope breakthrough def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules are formed by the extension of existing nuclear microtubules through a puncture in the nuclear envelope. Normally, cytoplasmic microtubules are nucleated from microtubule organizing centers in the cytoplasm." [PMID:15772152, PomBase:mah] comment: Also see 'long nuclear microtubules protruding through nuclear envelope during interphase' (FYPO:0004724). synonym: "cytoplasmic microtubule formation from nuclear microtubules following nuclear envelope breakthrough during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubule formation from nuclear microtubules following nuclear envelope breakthrough during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004727 ! cytoplasmic microtubule formation from nuclear microtubules created_by: midori creation_date: 2015-07-27T13:38:44Z [Term] id: FYPO:0004729 name: cytoplasmic microtubule formation from nuclear microtubules following spindle microtubule fragmentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules are formed by the extension of existing nuclear microtubules arising from fragmentation of the mitotic spindle. Normally, cytoplasmic microtubules are nucleated from microtubule organizing centers in the cytoplasm." [PMID:15772152, PomBase:mah] synonym: "cytoplasmic microtubule formation from nuclear microtubules following mitotic spindle microtubule fragmentation" EXACT [PomBase:mah] synonym: "cytoplasmic microtubule formation from nuclear microtubules following spindle microtubule fragmentation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubule formation from nuclear microtubules following spindle microtubule fragmentation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004727 ! cytoplasmic microtubule formation from nuclear microtubules created_by: midori creation_date: 2015-07-27T13:40:38Z [Term] id: FYPO:0004730 name: protein mislocalized to lateral cell cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the lateral cell cortex is observed there. The lateral cell cortex is the region directly beneath the plasma membrane of the lateral portion of the cell." [GO:0097575, PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the lateral cell cortex in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to lateral cell cortex" EXACT [PomBase:vw] synonym: "protein mislocalised to lateral cell cortex" EXACT [PomBase:mah] synonym: "protein mislocalised to lateral cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cell side during vegetative growth" RELATED [PomBase:vw] synonym: "protein mislocalized to lateral cell cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to lateral cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to lateral cortex" EXACT [PomBase:vw] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth relationship: output_of FYPO:0007869 ! abnormal protein localization to lateral cell cortex created_by: midori creation_date: 2015-07-27T13:55:26Z [Term] id: FYPO:0004731 name: normal protein localization to interphase microtubule plus-end alt_id: FYPO:0005812 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus-end of a cytoplasmic microtubule is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoplasmic microtubule plus-end during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localisation to interphase microtubule plus-end" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule plus end during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule plus-end during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule plus-end during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule plus-end during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to interphase cytoplasmic microtubule plus-end" EXACT [PomBase:mah] synonym: "normal protein localization to interphase microtubule plus end" EXACT [PomBase:mah] synonym: "normal protein localization to interphase microtubule plus-end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to interphase microtubule plus-end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0005813 ! normal protein localization to microtubule end during mitotic interphase is_a: FYPO:0005842 ! normal protein localization to interphase microtubule created_by: midori creation_date: 2015-07-27T14:07:56Z [Term] id: FYPO:0004732 name: astral microtubules present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer astral microtubules than normal." [PomBase:mah] synonym: "astral microtubules present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "astral microtubules present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "astral microtubules present in reduced numbers" EXACT [PomBase:mah] synonym: "decreased level of astral microtubules" EXACT [PomBase:mah] synonym: "reduced number of astral microtubules" EXACT [PomBase:vw] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2015-07-27T14:26:14Z [Term] id: FYPO:0004733 name: cytoplasmic microtubules nucleated from eMTOC present in decreased numbers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains fewer cytoplasmic microtubules nucleated from the equatorial microtubule organizing center than normal." [PMID:15772152, PomBase:mah] synonym: "cytoplasmic microtubules nucleated from eMTOC present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubules nucleated from eMTOC present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules nucleated from eMTOC present in reduced numbers" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules nucleated from equatorial microtubule organizing center present in decreased numbers" EXACT [PomBase:mah] synonym: "decreased number of cytoplasmic microtubules nucleated from eMTOC" EXACT [PomBase:vw] synonym: "reduced number of cytoplasmic microtubules nucleated from eMTOC" EXACT [PomBase:vw] is_a: FYPO:0003430 ! microtubules present in decreased numbers created_by: midori creation_date: 2015-07-27T14:39:08Z [Term] id: FYPO:0004734 name: decreased misfolded protein degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of degradation of misfolded or incompletely synthesized protein is decreased." [GO:0006515, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased misfolded or incompletely synthesized protein catabolic process" EXACT [GO:0006515, PomBase:mah] synonym: "decreased misfolded or incompletely synthesized protein degradation" EXACT [GO:0006515] synonym: "decreased misfolded protein degradation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased misfolded protein degradation during vegetative growth" EXACT [PomBase:mah] synonym: "misfolded or incompletely synthesized protein catabolism" EXACT [GO:0006515, PomBase:mah] synonym: "reduced misfolded protein degradation" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth created_by: midori creation_date: 2015-07-27T14:43:44Z [Term] id: FYPO:0004735 name: abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortical node, with protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to cortical medial dot, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein localization to cytokinetic nodes, with protein mislocalized to cytoplasm" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortical nodes, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "abolished protein recruitment to medial cortical node, with protein mislocalized to cytoplasm" RELATED [PomBase:vw] synonym: "protein localization to medial cortical node abolished, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0003919 ! abolished protein localization to medial cortical node relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2015-07-27T16:10:36Z [Term] id: FYPO:0004736 name: abnormal actomyosin contractile ring def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position, composition or morphology of the actomyosin contractile ring is abnormal." [PomBase:mah] synonym: "abnormal actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring" EXACT [PomBase:mah] synonym: "abnormal cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "abnormal mitotic contractile ring" EXACT [PomBase:vw] is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth relationship: output_of FYPO:0004738 ! abnormal actomyosin contractile ring organization created_by: midori creation_date: 2015-07-27T16:17:26Z [Term] id: FYPO:0004737 name: decreased F-actin level in actomyosin contractile ring during early mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is lower than normal during early mitosis (before anaphase)." [PMID:25688133, PomBase:mah] synonym: "decreased abundance of F-actin in the actomyosin contractile ring in early mitosis" EXACT [PomBase:vw] synonym: "decreased actomyosin contractile ring F-actin level during early mitosis" EXACT [PomBase:mah] synonym: "decreased F-actin level in actomyosin contractile ring during early mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased F-actin level in actomyosin contractile ring during early mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased F-actin level in mitotic contractile ring during early mitosis" EXACT [PomBase:vw] synonym: "decreased filamentous actin level in actomyosin contractile ring during early mitosis" EXACT [PomBase:mah] is_a: FYPO:0004736 ! abnormal actomyosin contractile ring created_by: midori creation_date: 2015-07-27T16:19:11Z [Term] id: FYPO:0004738 name: abnormal actomyosin contractile ring organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of the actomyosin contractile ring." [GO:0044837, PomBase:mah] synonym: "abnormal actomyosin contractile ring organisation" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring organization" EXACT [PomBase:mah] synonym: "abnormal mitotic contractile ring organization" EXACT [PomBase:vw] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2015-07-27T16:38:21Z [Term] id: FYPO:0004739 name: normal actin cytoskeleton during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of the actin cytoskeleton is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2015-07-27T16:44:24Z [Term] id: FYPO:0004740 name: normal actomyosin contractile ring def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position, composition or morphology of the of the actomyosin contractile ring is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2015-07-27T16:46:48Z [Term] id: FYPO:0004741 name: normal F-actin level in actomyosin contractile ring during anaphase B def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type) during mitotic anaphase B." [PMID:25688133, PomBase:mah] synonym: "normal abundance of actin in actomyosin contractile ring in anaphase B" EXACT [PomBase:vw] synonym: "normal actomyosin contractile ring F-actin level during anaphase B" EXACT [PomBase:mah] synonym: "normal F-actin level in actomyosin contractile ring during anaphase B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal F-actin level in actomyosin contractile ring during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "normal F-actin level in contractile ring during anaphase B" EXACT [PomBase:al] synonym: "normal F-actin level in cytokinetic contractile ring during anaphase B" EXACT [PomBase:vw] synonym: "normal filamentous actin level in actomyosin contractile ring during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0004740 ! normal actomyosin contractile ring created_by: midori creation_date: 2015-07-27T16:48:34Z [Term] id: FYPO:0004742 name: normal chromatin silencing at centromere outer repeat def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the outer repeat region of the centromere is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that the centromere outer repeat region corresponds to SO:0001799. Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "normal centromere outer repeat region chromatin silencing" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere outer repeat region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at centromere outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "normal chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "normal chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "normal heterochromatic silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "normal heterochromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] is_a: FYPO:0002360 ! normal chromatin silencing at centromere created_by: midori creation_date: 2015-07-28T11:03:58Z [Term] id: FYPO:0004743 name: normal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere outer repeat region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "normal histone H3K9me2 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth created_by: midori creation_date: 2015-07-28T11:13:39Z [Term] id: FYPO:0004744 name: normal heterochromatin maintenance involved in chromatin silencing at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin maintenance is normal (i.e. indistinguishable from wild type) in the context of chromatin silencing at centromere outer repeat regions." [GO:0070829, PMID:24240238, PomBase:mah] synonym: "normal heterochromatin maintenance involved in chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "normal heterochromatin maintenance involved in chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal heterochromatin maintenance involved in chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region" EXACT [GO:1902368, PomBase:mah] synonym: "normal heterochromatin maintenance involved in chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "normal heterochromatin maintenance involved in chromatin silencing at pericentromeric region" RELATED [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2015-07-28T11:25:15Z [Term] id: FYPO:0004745 name: abolished histone H3-K9 dimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere outer repeat region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3-K9 dimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone H3K9me2 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent at centromere outer repeat during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0004170 ! abolished histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2015-07-28T11:28:54Z [Term] id: FYPO:0004746 name: abolished heterochromatin assembly involved in chromatin silencing at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly involved in chromatin silencing at the centromere outer repeat region does not occur." [GO:0031507, PMID:24240238, PomBase:mah] synonym: "abolished heterochromatin assembly involved in chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "abolished heterochromatin assembly involved in chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished heterochromatin assembly involved in chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished heterochromatin assembly involved in chromatin silencing at centromere outer repeat region" EXACT [GO:1904497] synonym: "abolished heterochromatin assembly involved in chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "abolished heterochromatin assembly involved in chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "heterochromatin assembly involved in chromatin silencing at centromere outer repeat abolished" EXACT [PomBase:mah] is_a: FYPO:0003098 ! abnormal heterochromatin assembly at centromere outer repeat during vegetative growth created_by: midori creation_date: 2015-07-28T11:34:43Z [Term] id: FYPO:0004747 name: actin cortical patches present in increased numbers at cell tip during early mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cortical patches at one or both cell tips than normal during early mitosis (before anaphase)." [PMID:25688133, PomBase:mah] synonym: "accumulation of actin cortical patches at cell tip during early mitosis" RELATED [PomBase:vw] synonym: "actin cortical patches in increased numbers at cell tip during early mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "actin cortical patches present in greater numbers at cell tip during early mitosis" EXACT [PomBase:mah] synonym: "actin cortical patches present in increased numbers at cell end during early mitosis" EXACT [PomBase:mah] synonym: "actin cortical patches present in increased numbers at cell tip during cell growth during early mitotic nuclear division" EXACT [GO:0140014] synonym: "actin cortical patches present in increased numbers at cell tip during early mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin patches present in increased numbers at cell tip during early mitosis" EXACT [PomBase:mah] synonym: "actin patches present in increased numbers at cell tip during early mitosis" EXACT [PomBase:vw] synonym: "additional actin cortical patches present at cell tip during early mitosis" EXACT [PomBase:mah] synonym: "extra actin cortical patches at cell tip during early mitosis" EXACT [PomBase:mah] synonym: "F-actin patches present in increased numbers at cell tip during early mitosis" EXACT [PomBase:mah] synonym: "increased number of actin patches at cell tip in early mitosis" EXACT [PomBase:vw] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2015-07-28T11:49:16Z [Term] id: FYPO:0004748 name: decreased histone exchange at pericentric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:24095277, PomBase:mah] synonym: "decreased histone exchange at centromeric heterochromatin" EXACT [GO:0005721] synonym: "decreased histone exchange at dh repeat" NARROW [PomBase:al] synonym: "decreased histone exchange at pericentric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone exchange at pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone exchange at pericentric heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0006356 ! abnormal chromatin remodeling is_a: FYPO:0006359 ! decreased protein exchange at pericentric heterochromatin created_by: midori creation_date: 2015-07-28T12:20:18Z [Term] id: FYPO:0004749 name: increased spatial extent of subtelomeric heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the subtelomeric region of the chromosome than normal." [GO:0031509, PMID:25774602, PomBase:mah] synonym: "increased spatial extent of heterochromatin assembly at subtelomere" EXACT [PomBase:mah] synonym: "increased spatial extent of subtelomeric heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spatial extent of subtelomeric heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased spatial extent of subtelomeric heterochromatin formation" EXACT [GO:0031509] synonym: "increased spatial extent of telomeric heterochromatin assembly" RELATED [PomBase:mah, Pombase:vw] synonym: "subtelomeric heterochromatin spreading" RELATED [PMID:25774602] is_a: FYPO:0007953 ! increased spatial extent of heterochromatin assembly created_by: midori creation_date: 2015-07-28T12:26:06Z [Term] id: FYPO:0004750 name: elongated septated vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and has one or more septa." [PomBase:mah] synonym: "elongated septated cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated septated cells during vegetative growth" EXACT [PomBase:mah] synonym: "long septated cells" EXACT [PomBase:vw] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0002342 ! septated vegetative cell relationship: has_part FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2015-07-28T12:45:02Z [Term] id: FYPO:0004751 name: resistance to G418 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of G418 than normal." [PomBase:mah] synonym: "resistance to G418 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to G418 during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to Geneticin" EXACT [CHEBI:42768, PomBase:mah] synonym: "resistant to G418" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-07-28T13:01:45Z [Term] id: FYPO:0004752 name: resistance to phleomycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phleomycin than normal." [PomBase:mah] synonym: "resistance to phleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to phleomycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to phleomycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-07-28T13:02:43Z [Term] id: FYPO:0004753 name: abolished protein localization to nucleus during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleus during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear exclusion during mitotic interphase" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during mitotic interphase" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-07-28T13:33:52Z [Term] id: FYPO:0004754 name: abolished protein localization to mitotic spindle during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle does not occur during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to mitotic spindle during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to mitotic spindle during mitotic M-phase" RELATED [PomBase:vw] synonym: "abolished protein localization to mitotic spindle during mitotic nuclear division" EXACT [GO:0140014] synonym: "abolished protein localization to spindle during mitosis" EXACT [PomBase:mah] synonym: "protein absent from mitotic spindle during mitosis" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle abolished during mitosis" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle abolished during mitosis" EXACT [PomBase:mah] synonym: "protein localization to spindle abolished during mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003186 ! abolished protein localization to mitotic spindle created_by: midori creation_date: 2015-07-28T13:43:04Z [Term] id: FYPO:0004755 name: abnormal protein localization to microtubule minus-end def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the minus ends of microtubules is abnormal." [PMID:25987607, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to microtubule minus-end" EXACT [PomBase:mah] synonym: "abnormal protein localization to microtubule minus end" EXACT [PomBase:mah] synonym: "abnormal protein localization to microtubule minus-end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to microtubule minus-end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-07-28T13:54:16Z [Term] id: FYPO:0004756 name: abnormal regulation of DNA replication initiation def: "A regulation phenotype in which regulation of the initiation of DNA-dependent DNA replication is abnormal." [PomBase:mah] synonym: "abnormal regulation of DNA replication initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of DNA-dependent DNA replication initiation" EXACT [GO:0006270, PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2015-07-28T14:00:03Z [Term] id: FYPO:0004757 name: abnormal negative regulation of DNA replication initiation def: "A regulation phenotype in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal. May result in re-replication of all or part of the genome." [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation" EXACT [PomBase:mah] synonym: "DNA re-replication" RELATED [PomBase:mah] synonym: "DNA replication defects, endoreduplication" RELATED [PomBase:mah] synonym: "DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0004756 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2015-07-28T14:00:54Z [Term] id: FYPO:0004758 name: abnormal negative regulation of premeiotic DNA replication initiation def: "A regulation phenotype in which negative regulation of the initiation of premeiotic DNA replication is abnormal. May result in re-replication of all or part of the genome." [PomBase:mah] synonym: "abnormal negative regulation of initiation of premeiotic DNA replication" EXACT [GO:1904513] synonym: "premeiotic DNA re-replication" RELATED [PomBase:mah] synonym: "premeiotic DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0004756 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2015-07-28T14:15:28Z [Term] id: FYPO:0004759 name: abnormal negative regulation of premeiotic DNA replication initiation resulting in complete rereplication def: "A regulation phenotype in which negative regulation of the initiation of premeiotic DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome." [PMID:10388806, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication during meiotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of initiation of premeiotic DNA replication, resulting in complete rereplication" EXACT [GO:1904513] synonym: "abnormal negative regulation of premeiotic DNA replication initiation resulting in complete re-replication" EXACT [PomBase:mah] synonym: "complete premeiotic DNA re-replication" RELATED [PomBase:mah] synonym: "complete premeiotic DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0004758 ! abnormal negative regulation of premeiotic DNA replication initiation created_by: midori creation_date: 2015-07-28T14:16:58Z [Term] id: FYPO:0004760 name: abnormal sporulation resulting in formation of azygotic ascus with more than four spores def: "A sporulation phenotype in which azygotic asci that contain more than four, and up to eight, spores form following conjugation, diploid growth, and subsequent azygotic sporulation. Azygotic ascus formation occurs when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PomBase:mah, PomBase:vw] synonym: "8-spored azygotic asci" RELATED [PomBase:vw] synonym: "abnormal azygotic ascospore formation resulting in formation of asci with more than four spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of azygotic asci with more than four spores" EXACT [PomBase:mah] synonym: "azygotic asci with increased number of spores" EXACT [PomBase:vw] synonym: "eight-spored azygotic asci" RELATED [PomBase:vw] is_a: FYPO:0001893 ! abnormal sporulation resulting in formation of azygotic ascus with more or fewer than four spores is_a: FYPO:0003263 ! abnormal sporulation resulting in formation of ascus with more than four spores created_by: midori creation_date: 2015-07-28T14:26:07Z [Term] id: FYPO:0004761 name: increased histone exchange at pericentric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a greater extent than normal in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:24095277, PomBase:mah] synonym: "increased histone exchange at dh repeat" NARROW [PomBase:al] synonym: "increased histone exchange at pericentric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone exchange at pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006356 ! abnormal chromatin remodeling is_a: FYPO:0006360 ! increased protein exchange at pericentric heterochromatin is_a: FYPO:0007472 ! abnormal histone exchange created_by: midori creation_date: 2015-07-29T15:54:04Z [Term] id: FYPO:0004762 name: abnormal protein localization to kinetochore during meiosis def: "A cell phenotype in which the localization of a protein to the kinetochore is abnormal during one or both meiotic nuclear divisions." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the kinetochore and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to kinetochore during meiosis" EXACT [PomBase:mah] synonym: "abnormal protein localization to kinetochore during meiotic nuclear division" EXACT [GO:0140013] synonym: "abnormal protein localization to meiotic kinetochore" EXACT [PomBase:vw] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0005209 ! abnormal protein localization to kinetochore is_a: FYPO:0006529 ! abnormal protein localization to centromere during meiotic cell cycle created_by: midori creation_date: 2015-07-29T16:05:37Z [Term] id: FYPO:0004763 name: abolished protein localization to kinetochore during meiosis I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished protein localization to meiotic kinetochore during meiosis I" EXACT [PomBase:vw] synonym: "protein localization to kinetochore during meiosis I abolished" EXACT [PomBase:mah] is_a: FYPO:0004762 ! abnormal protein localization to kinetochore during meiosis created_by: midori creation_date: 2015-07-29T16:07:30Z [Term] id: FYPO:0004764 name: normal protein localization to meiotic spindle pole body during meiosis I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to meiotic spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to meiotic SPB during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to meiotic spindle pole body during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003541 ! normal protein localization to meiotic spindle pole body created_by: midori creation_date: 2015-07-29T16:10:12Z [Term] id: FYPO:0004765 name: normal cell population growth during glucose starvation def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal cell population growth during glucose depletion" EXACT [PomBase:mah] synonym: "normal cell population growth during glucose deprivation" EXACT [PomBase:mah] synonym: "normal cell population growth during glucose limitation" RELATED [PomBase:mah] synonym: "normal growth during glucose starvation" BROAD [PomBase:mah] is_a: FYPO:0000047 ! normal cell population growth created_by: midori creation_date: 2015-07-29T16:20:55Z [Term] id: FYPO:0004766 name: abolished cytoplasmic interphase microtubule nucleation def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from one or both of the normal nucleation sites does not occur during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB)." [GO:0051415, PMID:15772152, PomBase:mah] comment: This term can be used if microtubule nucleation is abolished from either the iMTOC or SPB, or from both sites. synonym: "abolished cytoplasmic interphase microtubule nucleation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished cytoplasmic interphase microtubule nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished interphase cytoplasmic microtubule nucleation" EXACT [PomBase:mah] synonym: "abolished interphase microtubule nucleation" EXACT [PomBase:vw] synonym: "cytoplasmic microtubule nucleation during mitotic interphase abolished" EXACT [PomBase:mah] is_a: FYPO:0000234 ! abnormal cytoplasmic interphase microtubule nucleation is_a: FYPO:0005693 ! abolished cytoplasmic microtubule nucleation created_by: midori creation_date: 2015-08-03T13:36:32Z [Term] id: FYPO:0004767 name: increased vacuolar alanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of alanine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar alanine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar alanine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar L-alanine level" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0003986 ! increased cellular amino acid level created_by: midori creation_date: 2015-08-03T14:03:37Z [Term] id: FYPO:0004768 name: increased vacuolar arginine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of arginine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar arginine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar arginine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar L-arginine level" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0005263 ! increased cellular arginine level created_by: midori creation_date: 2015-08-03T14:03:43Z [Term] id: FYPO:0004769 name: increased vacuolar asparagine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of asparagine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar asparagine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar asparagine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar L-asparagine level" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0006953 ! increased cellular asparagine level created_by: midori creation_date: 2015-08-03T14:03:46Z [Term] id: FYPO:0004770 name: increased vacuolar glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of glutamine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar glutamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar L-glutamine level" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0006955 ! increased cellular glutamine level created_by: midori creation_date: 2015-08-03T14:03:50Z [Term] id: FYPO:0004771 name: increased vacuolar glycine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of glycine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar glycine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar glycine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0003986 ! increased cellular amino acid level created_by: midori creation_date: 2015-08-03T14:04:01Z [Term] id: FYPO:0004772 name: increased vacuolar histidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of histidine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar histidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased vacuolar L-histidine level" EXACT [PomBase:mah] is_a: FYPO:0001567 ! increased cellular histidine level is_a: FYPO:0001730 ! increased level of substance in vacuole created_by: midori creation_date: 2015-08-03T14:04:08Z [Term] id: FYPO:0004773 name: increased vacuolar lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of lysine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar L-lysine level" EXACT [PomBase:mah] synonym: "increased vacuolar lysine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar lysine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0003986 ! increased cellular amino acid level created_by: midori creation_date: 2015-08-03T14:04:12Z [Term] id: FYPO:0004774 name: increased vacuolar proline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of proline in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar L-proline level" EXACT [PomBase:mah] synonym: "increased vacuolar proline level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar proline level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001730 ! increased level of substance in vacuole is_a: FYPO:0005237 ! increased cellular proline level created_by: midori creation_date: 2015-08-03T14:04:16Z [Term] id: FYPO:0004775 name: increased vacuolar serine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of serine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar L-serine level" EXACT [PomBase:mah] synonym: "increased vacuolar serine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar serine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001728 ! increased cellular serine level is_a: FYPO:0001730 ! increased level of substance in vacuole created_by: midori creation_date: 2015-08-03T14:04:20Z [Term] id: FYPO:0004776 name: increased vacuolar threonine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in the vacuole is higher than normal." [PomBase:mah] synonym: "increased level of threonine in vacuole" EXACT [PomBase:mah] synonym: "increased vacuolar L-threonine level" EXACT [PomBase:mah] synonym: "increased vacuolar threonine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased vacuolar threonine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001565 ! increased cellular threonine level is_a: FYPO:0001730 ! increased level of substance in vacuole created_by: midori creation_date: 2015-08-03T14:04:23Z [Term] id: FYPO:0004777 name: abnormal farnesyltranstransferase activity def: "A molecular function phenotype in which the observed rate of farnesyltranstransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-08-03T14:32:39Z [Term] id: FYPO:0004778 name: decreased farnesyltranstransferase activity def: "A molecular function phenotype in which the observed rate of farnesyltranstransferase activity is decreased." [PomBase:mah] synonym: "reduced farnesyltranstransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004777 ! abnormal farnesyltranstransferase activity created_by: midori creation_date: 2015-08-03T14:32:45Z [Term] id: FYPO:0004779 name: normal farnesyltranstransferase activity def: "A molecular function phenotype in which the observed rate of farnesyltranstransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-08-03T14:34:21Z [Term] id: FYPO:0004780 name: decreased protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is decreased, and some of the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to plasma membrane, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization in plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [GO:0072659] synonym: "decreased protein localization to plasma membrane, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0008198 ! decreased protein localization to plasma membrane during vegetative growth relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2015-08-03T14:35:38Z [Term] id: FYPO:0004781 name: delayed onset of mitotic G2 DNA damage checkpoint def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the mitotic G2 DNA damage checkpoint begins later than normal under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage." [PomBase:mah] synonym: "delayed mitotic G2 DNA damage checkpoint" EXACT [PomBase:mah] synonym: "delayed onset of G2 DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "delayed onset of mitotic G2 DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004373 ! abnormal mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2015-08-03T14:43:09Z [Term] id: FYPO:0004782 name: spores resistant to ionizing radiation def: "A cell phenotype in which spores germinate to a greater extent than wild type following exposure to ionizing radiation." [PMID:25533340, PomBase:mah] synonym: "resistant to ionizing radiation in spore phase" EXACT [PomBase:mah] synonym: "spores resistant to IR" EXACT [PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2015-08-03T14:54:34Z [Term] id: FYPO:0004783 name: abnormal histone methyltransferase activity def: "A molecular function phenotype in which the observed rate of a histone methyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-08-03T15:05:05Z [Term] id: FYPO:0004784 name: decreased histone methyltransferase activity def: "A molecular function phenotype in which the observed rate of a histone methyltransferase activity is decreased." [PomBase:mah] synonym: "reduced histone methyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004783 ! abnormal histone methyltransferase activity created_by: midori creation_date: 2015-08-03T15:05:12Z [Term] id: FYPO:0004785 name: increased RNA level during cellular response to menadione def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to menadione is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to menadione" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to menadione" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to menadione during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to menadione" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-08-03T15:14:58Z [Term] id: FYPO:0004786 name: decreased protein localization to Golgi apparatus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to Golgi apparatus" EXACT [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to Golgi apparatus" EXACT [PomBase:mah] is_a: FYPO:0003936 ! abnormal protein localization to Golgi apparatus created_by: midori creation_date: 2015-08-05T11:59:24Z [Term] id: FYPO:0004787 name: normal DNA/DNA annealing activity def: "A molecular function phenotype in which the observed rate of a DNA/DNA annealing activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2015-08-05T12:12:51Z [Term] id: FYPO:0004788 name: obsolete increased protein serine phosphorylation during glucose starvation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-serine phosphorylation during glucose starvation" EXACT [GO:0018105, PomBase:mah] synonym: "increased protein serine phosphorylation during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation during glucose depletion" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation during glucose deprivation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation during glucose limitation" RELATED [PomBase:mah] synonym: "increased serine phosphorylation during glucose starvation" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0005197 created_by: midori creation_date: 2015-08-05T12:13:36Z [Term] id: FYPO:0004789 name: circularized chromosome during mitotic G2 phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomeres have fused, forming circular chromosomes, during G2 phase of the mitotic cell cycle." [PMID:25533340, PomBase:mah] synonym: "circular chromosomes during mitotic G2 phase" EXACT [PomBase:mah] synonym: "circularised chromosome during mitotic G2 phase" EXACT [PomBase:mah] synonym: "circularized chromosome during G2 during vegetative growth" EXACT [PomBase:mah] synonym: "fused telomeres during mitotic G2 phase" RELATED [PomBase:mah] synonym: "telomere end fusion during mitotic G2 phase" RELATED [PomBase:mah] synonym: "telomere fusion during mitotic G2 phase" RELATED [PomBase:mah] synonym: "telomeres fused during mitotic G2 phase" RELATED [PomBase:mah] is_a: FYPO:0002702 ! circularized chromosome created_by: midori creation_date: 2015-08-05T12:16:51Z [Term] id: FYPO:0004790 name: abnormal telomere-nuclear envelope distance during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is abnormal (i.e. greater or less than the distance in wild type cells)." [PMID:22959349, PomBase:mah] synonym: "abnormal distance between telomeres and nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal telomere-nuclear envelope distance during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0001515 ! abnormal telomere tethering at nuclear periphery during vegetative growth created_by: midori creation_date: 2015-08-05T12:22:07Z [Term] id: FYPO:0004791 name: increased telomere-nuclear envelope distance during mitotic G2 phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is greater than normal during G2 phase of the mitotic cell cycle." [PMID:22959349, PomBase:mah] synonym: "increased distance between telomeres and nuclear envelope during mitotic G2 phase" EXACT [PomBase:mah] synonym: "increased telomere-nuclear envelope distance during G2 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased telomere-nuclear envelope distance during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004790 ! abnormal telomere-nuclear envelope distance during vegetative growth created_by: midori creation_date: 2015-08-05T12:29:09Z [Term] id: FYPO:0004792 name: decreased telomere-nuclear envelope distance during mitotic G2 phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is smaller than normal during G2 phase of the mitotic cell cycle." [PMID:22959349, PomBase:mah] synonym: "decreased distance between telomeres and nuclear envelope during mitotic G2 phase" EXACT [PomBase:mah] synonym: "decreased telomere-nuclear envelope distance during G2 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased telomere-nuclear envelope distance during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced telomere-nuclear envelope distance during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0004790 ! abnormal telomere-nuclear envelope distance during vegetative growth created_by: midori creation_date: 2015-08-05T12:31:42Z [Term] id: FYPO:0004793 name: decreased telomere-nuclear envelope distance during mitotic M phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is smaller than normal during mitosis." [PMID:22959349, PomBase:mah] synonym: "decreased distance between telomeres and nuclear envelope during mitosis" EXACT [PomBase:mah] synonym: "decreased telomere-nuclear envelope distance during M phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased telomere-nuclear envelope distance during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased telomere-nuclear envelope distance during mitotic M phase" RELATED [PomBase:mah] synonym: "reduced telomere-nuclear envelope distance during mitosis" EXACT [PomBase:mah] is_a: FYPO:0004790 ! abnormal telomere-nuclear envelope distance during vegetative growth created_by: midori creation_date: 2015-08-05T12:32:21Z [Term] id: FYPO:0004794 name: obsolete decreased protein phosphorylation at Ser/Thr-Pro site during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine or threonine residues N-terminal to proline residues (i.e. in Ser/Thr-Pro sequences) occurs to a lower extent than normal." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased protein phosphorylation at S/TP site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation at Ser/Thr-Pro site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation at serine/threonine-proline site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein serine or threonine phosphorylation at Ser/Thr-Pro site during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation at Ser/Thr-Pro site during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001838 created_by: midori creation_date: 2015-08-05T12:56:27Z [Term] id: FYPO:0004795 name: normal zygotic meiosis def: "A cellular process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type) during a cycle of zygotic meiosis and sporulation. Zygotic meiosis and sporulation take place under conditions of continuous nitrogen starvation, in which haploid cells of the opposite mating types conjugate to form diploid zygotes that proceed immediately to undergo meiosis and sporulation." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "normal meiosis during zygotic meiosis" EXACT [PomBase:vw] synonym: "normal zygotic meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0000478 ! normal meiosis created_by: midori creation_date: 2015-08-07T11:44:07Z [Term] id: FYPO:0004796 name: normal azygotic meiosis def: "A cellular process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type) during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "normal azygotic meiotic nuclear division" EXACT [GO:0140013] synonym: "normal meiosis during azygotic meiosis" EXACT [PomBase:vw] is_a: FYPO:0000478 ! normal meiosis created_by: midori creation_date: 2015-08-07T11:55:56Z [Term] id: FYPO:0004797 name: normal azygotic meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division is normal (i.e. indistinguishable from wild type) during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "normal azygotic first meiotic nuclear division" EXACT [GO:0140013] synonym: "normal meiosis I during azygotic meiosis" EXACT [PomBase:vw] is_a: FYPO:0003563 ! normal meiosis I created_by: midori creation_date: 2015-08-07T11:57:35Z [Term] id: FYPO:0004798 name: abolished azygotic meiosis II def: "A cellular process phenotype in which the second meiotic nuclear division does not occur during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "abolished azygotic second meiotic nuclear division" EXACT [GO:0140013] synonym: "abolished meiosis II during azygotic meiosis" EXACT [PomBase:vw] is_a: FYPO:0003379 ! abolished meiosis II created_by: midori creation_date: 2015-08-07T11:59:50Z [Term] id: FYPO:0004799 name: abolished zygotic meiosis II def: "A cellular process phenotype in which the second meiotic nuclear division does not occur during a cycle of zygotic meiosis and sporulation. Zygotic meiosis and sporulation take place under conditions of continuous nitrogen starvation, in which haploid cells of the opposite mating types conjugate to form diploid zygotes that proceed immediately to undergo meiosis and sporulation." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "abolished meiosis II during zygotic meiosis" EXACT [PomBase:vw] synonym: "abolished zygotic second meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0003379 ! abolished meiosis II created_by: midori creation_date: 2015-08-07T12:01:35Z [Term] id: FYPO:0004800 name: abolished premeiotic DNA replication during azygotic meiotic cell cycle def: "A cellular process phenotype in which premeiotic DNA replication does not occur during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "abolished DNA replication before azygotic meiotic cell cycle" EXACT [PomBase:mah] synonym: "abolished premeiotic DNA replication during azygotic meiosis" RELATED [PomBase:mah] synonym: "abolished premeiotic DNA replication during azygotic meiosis and sporulation" EXACT [PomBase:mah] synonym: "absent premeiotic DNA replication during azygotic meiotic cell cycle" EXACT [PomBase:mah] synonym: "premeiotic DNA replication abolished during azygotic meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0002044 ! abolished premeiotic DNA replication created_by: midori creation_date: 2015-08-07T12:03:30Z [Term] id: FYPO:0004801 name: delayed onset of premeiotic DNA replication during azygotic meiosis def: "A cellular process phenotype in which premeiotic DNA replication begins later than normal during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:22558440, PMID:25891897, PomBase:mah] synonym: "delayed onset of DNA replication before azygotic meiotic cell cycle" EXACT [PomBase:mah] synonym: "delayed onset of premeiotic DNA replication during azygotic meiosis" RELATED [PomBase:mah] synonym: "delayed onset of premeiotic DNA replication during azygotic meiosis and sporulation" EXACT [PomBase:mah] synonym: "delayed premeiotic DNA replication during azygotic meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004628 ! delayed onset of premeiotic DNA replication created_by: midori creation_date: 2015-08-07T12:06:12Z [Term] id: FYPO:0004802 name: abnormal protein localization to shmoo tip def: "A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to shmoo tip" EXACT [PomBase:mah] synonym: "abnormal protein localization to mating projection tip" EXACT [PomBase:mah] synonym: "abnormal protein localization to shmoo projection" RELATED [PomBase:al] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2015-08-11T14:49:17Z [Term] id: FYPO:0004803 name: abnormal actin cytoskeleton organization def: "A cellular process phenotype in which actin cytoskeleton organization is abnormal." [GO:0030036, PMID:19713940, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton' (FYPO:0002398), but note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton organisation" EXACT [PomBase:mah] is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype is_a: FYPO:0000802 ! abnormal cytoskeleton organization created_by: midori creation_date: 2015-08-11T14:55:28Z [Term] id: FYPO:0004804 name: abolished actin fusion focus assembly def: "A cellular process phenotype in which actin fusion focus assembly does not occur. An actin fusion focus normally forms during mating at the site where the two cells will fuse." [PMID:25825517, PomBase:mah] synonym: "abolished actin fusion focus formation" EXACT [PomBase:mah] synonym: "actin fusion focus assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0006108 ! abnormal actin fusion focus assembly created_by: midori creation_date: 2015-08-11T14:59:56Z [Term] id: FYPO:0004805 name: abnormal cell wall organization def: "A cellular process phenotype in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GO:0031505, PomBase:mah] synonym: "abnormal cell wall organisation" RELATED [PomBase:mah] synonym: "abnormal fungal-type cell wall organization" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2015-08-11T15:06:43Z [Term] id: FYPO:0004806 name: incomplete cell wall disassembly at cell fusion site def: "A cellular process phenotype in which the cell wall is broken down to a lesser extent than in wild type at the site of cell-cell fusion during mating." [PMID:25825517, PomBase:mah] synonym: "incomplete cell wall disassembly at cell fusion site during conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "incomplete cell wall disassembly at cell fusion site during mating" EXACT [PomBase:mah] synonym: "incomplete cell wall disassembly at cell-cell fusion focus" EXACT [PomBase:al] synonym: "incomplete cell wall disassembly at cell-cell fusion site" EXACT [PomBase:mah] synonym: "incomplete fungal-type cell wall disassembly at cell fusion site" EXACT [GO:0071853] synonym: "incomplete fungal-type cell wall disassembly involved in conjugation with cellular fusion" EXACT [GO:1904541] is_a: FYPO:0004805 ! abnormal cell wall organization is_a: FYPO:0006499 ! abnormal cell wall disassembly at cell fusion site created_by: midori creation_date: 2015-08-11T15:08:11Z [Term] id: FYPO:0004807 name: narrow cell fusion site following mating def: "A cell morphology phenotype in which the cell is narrower than normal at the point where cell fusion occurred during mating. Normally, the cell expands at the fusion site after fusion takes place." [PMID:25825517, PomBase:mah] synonym: "narrow cell fusion site following conjugation" EXACT [PomBase:mah] synonym: "narrow cell fusion site following conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "narrow cell-cell fusion site following conjugation with cellular fusion" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2015-08-11T15:13:53Z [Term] id: FYPO:0004808 name: increased cellular protein aggregate level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein present as aggregates of misfolded protein is greater than normal during a cellular response to heat." [PMID:25543137, PomBase:mah] synonym: "increased cellular protein aggregate level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular protein aggregate level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003152 ! increased protein level during cellular response to heat is_a: FYPO:0004180 ! increased cellular protein aggregate level created_by: midori creation_date: 2015-08-11T15:18:43Z [Term] id: FYPO:0004809 name: decreased duration of heterochromatin maintenance involved in chromatin silencing at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of heterochromatin maintenance is shorter than normal in the context of chromatin silencing at centromere outer repeat regions." [GO:0070829, PMID:25543137, PomBase:mah] synonym: "decreased duration of heterochromatin maintenance involved in chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "decreased duration of heterochromatin maintenance involved in chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of heterochromatin maintenance involved in chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region" EXACT [GO:1902368, PomBase:mah] synonym: "decreased duration of heterochromatin maintenance involved in chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "decreased duration of heterochromatin maintenance involved in chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "reduced duration of heterochromatin maintenance involved in chromatin silencing at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0008366 ! decreased duration of heterochromatin maintenance created_by: midori creation_date: 2015-08-11T15:20:50Z [Term] id: FYPO:0004810 name: decreased protein localization to nucleus, with protein mislocalized to cytoplasmic foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased, and the protein is instead visible in one or a few foci or dots in the cytoplasm." [PMID:25543137, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus, with protein mislocalised to cytoplasmic foci" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus, with protein mislocalized to cytoplasmic foci, during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus, with protein mislocalized to cytoplasmic foci, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004056 ! decreased protein localization to nucleus, with protein mislocalized to cytoplasm created_by: midori creation_date: 2015-08-11T15:23:29Z [Term] id: FYPO:0004811 name: abnormal termination of RNA polymerase II transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II is abnormal. Termination of all transcripts, or a subset of transcripts, may be affected." [GO:0006369, PomBase:mah] synonym: "abnormal RNA polymerase II transcription termination" EXACT [GO:0006369] synonym: "abnormal termination of RNA polymerase II transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal termination of RNA polymerase II transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004064 ! abnormal transcription during vegetative growth created_by: midori creation_date: 2015-08-17T12:21:31Z [Term] id: FYPO:0004812 name: abnormal termination of RNA polymerase II transcription at rDNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at sites in ribosomal DNA (rDNA) is abnormal." [PMID:25417108, PomBase:mah] comment: Although rDNA is normally transcribed by RNA polymerase I, RNA polymerase II mediates antisense transcription in subtelomeric rDNA repeats on chromosome III. synonym: "abnormal RNA polymerase II release at rDNA" RELATED [PMID:25417108] synonym: "abnormal RNA polymerase II transcription termination at rDNA" EXACT [GO:0006369] synonym: "abnormal termination of RNA polymerase II transcription at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal termination of RNA polymerase II transcription at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal termination of RNA polymerase II transcription at ribosomal DNA" RELATED [PomBase:mah] is_a: FYPO:0004811 ! abnormal termination of RNA polymerase II transcription created_by: midori creation_date: 2015-08-17T12:29:00Z [Term] id: FYPO:0004813 name: abnormal termination of RNA polymerase II transcription at tDNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at tRNA genes (tDNA) is abnormal." [PMID:25417108, PomBase:mah] comment: Although tDNA is normally transcribed by RNA polymerase III, RNA polymerase II mediates antisense transcription at some tRNA genes. synonym: "abnormal RNA polymerase II release at tDNA" RELATED [PMID:25417108] synonym: "abnormal RNA polymerase II transcription termination at tDNA" EXACT [GO:0006369] synonym: "abnormal termination of RNA polymerase II transcription at tDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal termination of RNA polymerase II transcription at tDNA during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal termination of RNA polymerase II transcription at transfer RNA genes" RELATED [PomBase:mah] is_a: FYPO:0004811 ! abnormal termination of RNA polymerase II transcription created_by: midori creation_date: 2015-08-17T12:48:13Z [Term] id: FYPO:0004814 name: abnormal termination of RNA polymerase II transcription at highly transcribed protein-coding genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at highly transcribed protein-coding genes is abnormal." [PMID:25417108, PomBase:mah] synonym: "abnormal RNA polymerase II release at highly transcribed protein-coding genes" RELATED [PMID:25417108] synonym: "abnormal RNA polymerase II transcription termination at highly transcribed protein-coding genes" EXACT [GO:0006369] synonym: "abnormal termination of RNA polymerase II transcription at highly transcribed protein-coding genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal termination of RNA polymerase II transcription at highly transcribed protein-coding genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004811 ! abnormal termination of RNA polymerase II transcription created_by: midori creation_date: 2015-08-17T13:03:10Z [Term] id: FYPO:0004815 name: increased rDNA antisense siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of siRNA derived from antisense transcription of ribosomal DNA measured in a cell is greater than normal." [PMID:25417108, PomBase:mah] synonym: "increased accumulation of rDNA antisense small RNAs" RELATED [PomBase:mah] synonym: "increased antisense small RNA at rDNA" EXACT [PomBase:al] synonym: "increased antisense transcription-derived small RNA level at rDNA" EXACT [PomBase:al] synonym: "increased rDNA antisense small RNA accumulation" RELATED [PomBase:mah] synonym: "increased rDNA antisense small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rDNA antisense small RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003557 ! increased antisense RNA level created_by: midori creation_date: 2015-08-17T13:12:23Z [Term] id: FYPO:0004816 name: decreased antisense RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell is lower than normal. Antisense RNA is transcribed from the coding, rather than the template, strand of DNA." [PomBase:mah, SO:0000644] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased antisense RNA accumulation" RELATED [PomBase:mah] synonym: "decreased antisense RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased antisense RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased antisense RNA transcript level" EXACT [PomBase:vw] synonym: "decreased level of antisense transcripts" EXACT [PomBase:al] synonym: "reduced antisense RNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0005857 ! altered antisense RNA level during vegetative growth created_by: midori creation_date: 2015-08-17T13:23:10Z [Term] id: FYPO:0004817 name: decreased rDNA antisense small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of ribosomal DNA measured in a cell is lower than normal." [PMID:25417108, PomBase:mah] synonym: "decreased accumulation of rDNA antisense small RNAs" RELATED [PomBase:mah] synonym: "decreased antisense small RNA at rDNA" EXACT [PomBase:al] synonym: "decreased antisense transcription-derived small RNA level at rDNA" EXACT [PomBase:al] synonym: "decreased rDNA antisense small RNA accumulation" RELATED [PomBase:mah] synonym: "decreased rDNA antisense small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rDNA antisense small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rDNA antisense small RNA level" EXACT [PomBase:mah] is_a: FYPO:0004816 ! decreased antisense RNA level created_by: midori creation_date: 2015-08-17T13:24:20Z [Term] id: FYPO:0004818 name: decreased tDNA antisense small RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of transfer RNA genes measured in a cell is lower than normal." [PMID:25417108, PomBase:mah] synonym: "decreased accumulation of tDNA antisense small RNAs" RELATED [PomBase:mah] synonym: "decreased antisense small RNA at tDNA" EXACT [PomBase:al] synonym: "decreased antisense transcription-derived small RNA level at tDNA" EXACT [PomBase:al] synonym: "decreased tDNA antisense small RNA accumulation" RELATED [PomBase:mah] synonym: "decreased tDNA antisense small RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tDNA antisense small RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced tDNA antisense small RNA level" EXACT [PomBase:mah] is_a: FYPO:0004816 ! decreased antisense RNA level created_by: midori creation_date: 2015-08-17T13:26:30Z [Term] id: FYPO:0004819 name: increased number of Rad52 foci at rDNA replication origins def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of DNA replication origins in ribosomal DNA at which the protein Rad52 (also called Rad22) accumulates is greater than normal." [PMID:25417108, PomBase:mah] synonym: "increased number of Rad22 foci at rDNA replication origins" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci at rDNA replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci at rDNA replication origins during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci at ribosomal DNA replication origins" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2015-08-17T13:34:59Z [Term] id: FYPO:0004820 name: increased number of Rad52 foci at rDNA replication pause sites def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of DNA replication pause sites in ribosomal DNA at which the protein Rad52 (also called Rad22) accumulates is greater than normal." [PMID:25417108, PomBase:mah] synonym: "increased number of Rad22 foci at rDNA replication fork barrier" EXACT [SO:0001914] synonym: "increased number of Rad22 foci at rDNA replication pause sites" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci at rDNA replication pause sites during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci at rDNA replication pause sites during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2015-08-17T13:37:05Z [Term] id: FYPO:0004821 name: decreased number of Rad52 foci at highly transcribed protein-coding genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates at or near highly transcribed protein-coding genes is lower than normal." [PMID:25417108, PomBase:mah] synonym: "decreased number of Rad22 foci at highly transcribed protein-coding genes" EXACT [PomBase:mah] synonym: "decreased number of Rad52 foci at highly transcribed protein-coding genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Rad52 foci at highly transcribed protein-coding genes during vegetative growth" RELATED [PomBase:mah] synonym: "reduced number of Rad52 foci at highly transcribed protein-coding genes" EXACT [PomBase:mah] is_a: FYPO:0004516 ! decreased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2015-08-17T13:38:59Z [Term] id: FYPO:0004822 name: increased number of R-loops at rDNA def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal in ribosomal DNA regions." [PMID:25417108, PomBase:mah] synonym: "increased level of DNA:RNA hybrids at rDNA" EXACT [PomBase:al] synonym: "increased level of RNA-DNA hybrids at rDNA" EXACT [] synonym: "increased level of RNA-DNA hybrids at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of RNA-DNA hybrids at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA-DNA hybrid level at rDNA" EXACT [PomBase:mah] is_a: FYPO:0007901 ! increased number of R-loops created_by: midori creation_date: 2015-08-17T13:42:59Z [Term] id: FYPO:0004823 name: abnormal rDNA copy number def: "A physical cellular phenotype in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is abnormal (significantly greater or less than the range in wild type cells)." [PMID:25417108, PomBase:mah] synonym: "abnormal ribosomal DNA copy number" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2015-08-17T13:51:19Z [Term] id: FYPO:0004824 name: normal rDNA copy number def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is normal (within the range in wild type cells)." [PMID:25417108, PomBase:mah] synonym: "normal rDNA copy number during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rDNA copy number during vegetative growth" EXACT [PomBase:mah] synonym: "normal ribosomal DNA copy number" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2015-08-17T13:56:52Z [Term] id: FYPO:0004825 name: stably decreased rDNA copy number during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells, but remains at the same level over successive generations." [PMID:25417108, PomBase:mah] synonym: "stable shortened rDNA during vegetative growth" RELATED [PomBase:al] synonym: "stably decreased rDNA copy number during mitotic cell cycle" RELATED [PomBase:mah] synonym: "stably decreased ribosomal DNA copy number during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006494 ! decreased rDNA copy number during vegetative growth created_by: midori creation_date: 2015-08-17T13:57:35Z [Term] id: FYPO:0004826 name: progressively decreasing rDNA copy number during successive meiotic generations def: "A physical cellular phenotype in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells, and continues to decrease over successive meiotic generations (i.e. cycles of mating, meiosis, sporulation, spore germination and vegetative growth)." [PMID:25417108, PomBase:mah] synonym: "progressively decreasing rDNA copy number over successive meiotic generations" EXACT [PomBase:mah] synonym: "progressively decreasing ribosomal DNA copy number during successive meiotic generations" EXACT [PomBase:mah] synonym: "progressively shortening rDNA through meiotic generations" RELATED [PomBase:al] is_a: FYPO:0004823 ! abnormal rDNA copy number created_by: midori creation_date: 2015-08-17T14:04:34Z [Term] id: FYPO:0004827 name: inviable vegetative cell with cell death during mitosis def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell dies as it goes through mitosis, usually as a result of abnormal chromosome and spindle dynamics." [PMID:16824200, PomBase:mah] synonym: "inviable cell with cell death during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "inviable vegetative cell with cell death during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; vegetative cell with cell death during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2015-08-17T14:20:20Z [Term] id: FYPO:0004828 name: normal protein localization to nucleus during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during mitosis" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-08-17T14:23:30Z [Term] id: FYPO:0004829 name: decreased phosphatase activity during cellular response to adenine starvation def: "A molecular function phenotype in which the observed rate of a phosphatase activity is decreased during a cellular response to adenine starvation." [PomBase:mah] synonym: "decreased phosphatase activity during adenine starvation" EXACT [PomBase:al] synonym: "reduced phosphatase activity during cellular response to adenine starvation" EXACT [PomBase:mah] is_a: FYPO:0004304 ! decreased phosphatase activity created_by: midori creation_date: 2015-08-18T11:26:50Z [Term] id: FYPO:0004830 name: arrested mitotic spindle elongation during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation ends earlier than normal during anaphase B. Elongation stops before the spindle reaches its normal maximum length." [PMID:16824200, PomBase:mah] synonym: "arrested mitotic spindle elongation during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "arrested mitotic spindle extension during anaphase B" EXACT [PomBase:vw] synonym: "arrested spindle elongation during anaphase B during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic spindle elongation arrested during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2015-08-17T14:28:09Z [Term] id: FYPO:0004831 name: decreased protein localization to mitotic spindle midzone during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased during anaphase. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1902967, GO:1990023, PMID:16824200, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle midzone during anaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone during mitotic anaphase" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle midzone during anaphase" EXACT [PomBase:mah] is_a: FYPO:0003841 ! decreased protein localization to mitotic spindle midzone created_by: midori creation_date: 2015-08-17T14:30:01Z [Term] id: FYPO:0004832 name: abolished protein localization to mitotic spindle midzone during anaphase A def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase A does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase A is the stage of mitosis in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [GO:0000091, GO:1902967, GO:1990023, PMID:16824200, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to spindle midzone during mitotic anaphase A" EXACT [PomBase:mah] synonym: "protein absent from mitotic spindle midzone during anaphase A" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle midzone abolished during anaphase A" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle midzone abolished during anaphase A" EXACT [PomBase:mah] synonym: "protein localization to spindle midzone abolished during anaphase A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003484 ! abolished protein localization to mitotic spindle midzone created_by: midori creation_date: 2015-08-17T14:31:55Z [Term] id: FYPO:0004833 name: decreased protein localization to mitotic spindle midzone during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased during anaphase B. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart." [GO:0000092, GO:1902967, GO:1990023, PMID:16824200, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle midzone during anaphase B" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone during mitotic anaphase B" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle midzone during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2015-08-17T14:35:30Z [Term] id: FYPO:0004834 name: increased phosphatase activity during cellular response to adenine starvation def: "A molecular function phenotype in which the observed rate of a phosphatase activity is increased during a cellular response to adenine starvation." [PomBase:mah] synonym: "increased phosphatase activity during adenine starvation" EXACT [PomBase:al] is_a: FYPO:0004415 ! increased phosphatase activity created_by: midori creation_date: 2015-08-18T11:27:53Z [Term] id: FYPO:0004835 name: abolished protein localization to nucleus during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleus during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear exclusion during cellular response to hydrogen peroxide" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during cellular response to hydrogen peroxide" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-08-18T11:32:08Z [Term] id: FYPO:0004836 name: decreased protein oxidation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is decreased during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein oxidation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:al] synonym: "decreased protein oxidation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein oxidation during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0000545 ! decreased protein modification during vegetative growth created_by: midori creation_date: 2015-08-18T11:33:42Z [Term] id: FYPO:0004837 name: abolished cell population growth during glucose starvation def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing little or no glucose." [PMID:25411338, PomBase:mah] comment: Use this term for a population of cells that does not grow under conditions where glucose is absent or limiting (below about 4.4 mM (0.08%)), but does grow using a different carbon source or when more glucose is available (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abolished cell population growth during glucose depletion" EXACT [PomBase:mah] synonym: "abolished cell population growth during glucose deprivation" EXACT [PomBase:mah] synonym: "abolished cell population growth during glucose limitation" RELATED [PomBase:mah] synonym: "abolished growth during glucose starvation" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth during glucose starvation" EXACT [PomBase:mah] synonym: "cell population growth during glucose starvation abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2015-08-18T14:03:57Z [Term] id: FYPO:0004838 name: abnormal protein localization to plasma membrane def: "A cell phenotype observed in which the localization of a protein to the plasma membrane is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the plasma membrane and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to plasma membrane" EXACT [PomBase:mah] synonym: "abnormal protein localization in plasma membrane" EXACT [GO:0072659] synonym: "abnormal protein localization to cell membrane" EXACT [GO:0005886, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2015-08-18T14:09:59Z [Term] id: FYPO:0004839 name: abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during glucose starvation def: "A cell phenotype observed in which the localization of a protein to the plasma membrane is abolished when the cell is subject to glucose starvation, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abolished protein localisation to plasma membrane, with protein mislocalised to cytoplasm, during glucose starvation" EXACT [PomBase:mah] synonym: "abolished protein localization in plasma membrane, with protein mislocalized to cytoplasm, during glucose starvation" EXACT [GO:0072659] synonym: "abolished protein localization to cell membrane, with protein mislocalized to cytoplasm, during glucose starvation" EXACT [GO:0005886] synonym: "abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during glucose depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during glucose deprivation" EXACT [PomBase:mah] synonym: "abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during glucose limitation" RELATED [PomBase:mah] synonym: "protein localization to plasma membrane abolished, with protein mislocalized to cytoplasm, during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0004838 ! abnormal protein localization to plasma membrane is_a: FYPO:0004842 ! protein mislocalized to cytoplasm relationship: has_part FYPO:0004842 ! protein mislocalized to cytoplasm created_by: midori creation_date: 2015-08-18T14:13:40Z [Term] id: FYPO:0004840 name: abnormal high-affinity glucose import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which high-affinity import of glucose into the cell is abnormal." [PomBase:mah] synonym: "abnormal high-affinity glucose import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal high-affinity glucose import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal high-affinity glucose import into cell" EXACT [PomBase:al] synonym: "abnormal high-affinity glucose uptake" EXACT [PomBase:mah] is_a: FYPO:0001827 ! abnormal glucose import created_by: midori creation_date: 2015-08-18T14:17:46Z [Term] id: FYPO:0004841 name: protein mislocalized to nucleus during glucose starvation def: "A cell phenotype in which a protein that is not normally found in the nucleus is observed there when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "ectopic protein localization to nucleus during glucose starvation" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleus during glucose starvation" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during glucose depletion" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during glucose deprivation" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during glucose limitation" RELATED [PomBase:mah] is_a: FYPO:0003453 ! protein mislocalized to nucleus created_by: midori creation_date: 2015-08-18T14:27:11Z [Term] id: FYPO:0004842 name: protein mislocalized to cytoplasm def: "A cell phenotype observed in which a protein that is not normally found in the cytoplasm is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the cytoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to cytoplasm" EXACT [PomBase:vw] synonym: "protein mislocalised to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0003452 ! mislocalized protein created_by: midori creation_date: 2015-08-18T14:34:05Z [Term] id: FYPO:0004843 name: multiseptate vegetative cell with binucleate and anucleate compartments def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and more than one septum, and the septa are grouped together between two compartments, one contains both nuclei." [PMID:25203555, PomBase:mah] synonym: "multiseptate cell with binucleate and anucleate compartments during vegetative growth" EXACT [PomBase:mah] synonym: "multiseptate vegetative cell with binucleate and anucleate compartments during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2015-08-26T12:56:53Z [Term] id: FYPO:0004844 name: abnormal mitotic DNA replication lagging strand elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lagging strand elongation during nuclear DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA replication lagging strand elongation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal DNA replication lagging strand elongation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic DNA replication lagging strand synthesis" EXACT [PomBase:al] is_a: FYPO:0006730 ! abnormal mitotic DNA replication elongation created_by: midori creation_date: 2015-08-26T14:30:48Z [Term] id: FYPO:0004845 name: abnormal mitotic DNA replication lagging strand elongation at telomere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lagging strand elongation during nuclear DNA replication is abnormal at telomeric regions." [PMID:26041456, PomBase:mah] synonym: "abnormal DNA replication lagging strand elongation at telomere during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal DNA replication lagging strand elongation at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic DNA replication lagging strand synthesis at telomere" EXACT [PomBase:al] is_a: FYPO:0004844 ! abnormal mitotic DNA replication lagging strand elongation created_by: midori creation_date: 2015-08-26T14:40:13Z [Term] id: FYPO:0004846 name: increased number of Rad52 foci at telomeres def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of DNA replication pause sites in telomeric regions at which the protein Rad52 (also called Rad22) accumulates is greater than normal." [PMID:26041456, PomBase:mah] synonym: "increased number of Rad22 foci at telomeres" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci at telomeres during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci at telomeres during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2015-08-26T14:42:20Z [Term] id: FYPO:0004847 name: transcription phenotype def: "A cellular process phenotype that affects DNA-dependent transcription." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast transcription phenotype" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000294 ! RNA metabolism phenotype created_by: midori creation_date: 2015-08-26T14:59:27Z [Term] id: FYPO:0004848 name: normal protein transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0005747 ! normal protein transport created_by: midori creation_date: 2015-08-26T15:15:29Z [Term] id: FYPO:0004849 name: normal protein metabolic process def: "A cellular process phenotype in which a protein metabolic process is normal (i.e. indistinguishable from wild type). A protein metabolic process is a series of chemical reactions and pathways involving a specific protein." [GO:0019538, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal cellular protein metabolic process" EXACT [PomBase:mah] synonym: "normal protein metabolism" EXACT [GO:0019538] is_a: FYPO:0002496 ! normal metabolic process created_by: midori creation_date: 2015-08-26T15:36:24Z [Term] id: FYPO:0004850 name: normal RNA metabolic process def: "A cellular process phenotype in which a protein metabolic process is normal (i.e. indistinguishable from wild type). An RNA metabolic process is a series of chemical reactions and pathways involving any type of RNA." [GO:0016070, PomBase:mah] synonym: "normal RNA metabolism" EXACT [GO:0016070] is_a: FYPO:0002496 ! normal metabolic process created_by: midori creation_date: 2015-08-26T15:49:11Z [Term] id: FYPO:0004851 name: abnormal RNA metabolic process def: "A cellular process phenotype in which a protein metabolic process is abnormal. An RNA metabolic process is a series of chemical reactions and pathways involving any type of RNA." [GO:0016070, PomBase:mah] synonym: "abnormal RNA metabolism" EXACT [GO:0016070] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2015-08-26T15:50:46Z [Term] id: FYPO:0004852 name: RNA transport phenotype def: "A cell process phenotype that affects an RNA transport process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000149 ! transport phenotype is_a: FYPO:0004853 ! RNA localization phenotype created_by: midori creation_date: 2015-08-26T15:52:33Z [Term] id: FYPO:0004853 name: RNA localization phenotype def: "A cell phenotype that affects the localization of an RNA in a cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast RNA localization phenotype" EXACT [PomBase:mah] synonym: "RNA localisation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype created_by: midori creation_date: 2015-08-26T15:54:27Z [Term] id: FYPO:0004854 name: increased protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "increased protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "increased protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "increased protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "increased protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2015-08-26T16:01:02Z [Term] id: FYPO:0004855 name: abnormal negative regulation of premeiotic DNA replication initiation resulting in partial rereplication def: "A regulation phenotype in which negative regulation of the initiation of premeiotic DNA replication is abnormal, resulting in rereplication of part of the genome." [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in partial rereplication during meiotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of initiation of premeiotic DNA replication, resulting in partial rereplication" EXACT [GO:1904513] synonym: "abnormal negative regulation of premeiotic DNA replication initiation resulting in partial re-replication" EXACT [PomBase:mah] synonym: "partial premeiotic DNA re-replication" RELATED [PomBase:mah] synonym: "partial premeiotic DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0004758 ! abnormal negative regulation of premeiotic DNA replication initiation created_by: midori creation_date: 2015-08-26T16:13:31Z [Term] id: FYPO:0004856 name: abnormal endo-1,6-beta-glucosidase activity def: "A molecular function phenotype in which the observed rate of glucan endo-1,6-beta-glucosidase activity is abnormal." [PomBase:mah] synonym: "abnormal glucan endo-1,6-beta-glucosidase activity" EXACT [GO:0046557] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-09-01T13:32:54Z [Term] id: FYPO:0004857 name: increased endo-1,6-beta-glucosidase activity def: "A molecular function phenotype in which the observed rate of glucan endo-1,6-beta-glucosidase activity is increased." [PomBase:mah] synonym: "increased glucan endo-1,6-beta-glucosidase activity" EXACT [GO:0046557] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004856 ! abnormal endo-1,6-beta-glucosidase activity created_by: midori creation_date: 2015-09-01T13:33:00Z [Term] id: FYPO:0004858 name: normal growth on Congo Red def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Congo Red." [PomBase:mah] synonym: "normal cell population growth in presence of Congo Red" EXACT [PomBase:mah] synonym: "normal cell population growth on Congo Red" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to Congo Red" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on Congo Red" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-09-01T13:39:45Z [Term] id: FYPO:0004859 name: increased cell wall polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more polysaccharides measured in the cell wall is greater than normal." [PomBase:mah] synonym: "increased cell wall polysaccharide accumulation" RELATED [PomBase:mah] synonym: "increased cell wall polysaccharide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell wall polysaccharide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth is_a: FYPO:0002627 ! altered level of substance in cell wall during vegetative growth relationship: output_of FYPO:0000174 ! abnormal cell wall biogenesis created_by: midori creation_date: 2015-09-01T13:41:44Z [Term] id: FYPO:0004860 name: increased cell wall beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is greater than normal." [PomBase:mah] synonym: "increased cell wall beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "increased cell wall beta-glucan accumulation" RELATED [PomBase:mah] synonym: "increased cell wall beta-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell wall beta-glucan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001194 ! increased beta-glucan level is_a: FYPO:0004859 ! increased cell wall polysaccharide level created_by: midori creation_date: 2015-09-01T13:41:52Z [Term] id: FYPO:0004861 name: normal cell wall galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell wall galactomannan accumulation" RELATED [PomBase:mah] synonym: "normal cell wall galactomannan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell wall galactomannan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001079 ! normal galactomannan level created_by: midori creation_date: 2015-09-01T13:45:36Z [Term] id: FYPO:0004862 name: curved microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are curved, i.e. follow a smooth bend rather than a straight line." [PomBase:mah] synonym: "curved microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "curved microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth created_by: midori creation_date: 2015-09-23T11:56:09Z [Term] id: FYPO:0004863 name: long curved microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal and are curved, i.e. follow a smooth bend rather than a straight line." [PomBase:mah] synonym: "elongated curved microtubules" EXACT [PomBase:mah] synonym: "long curved microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long curved microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defects, long curved microtubules" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth relationship: has_part FYPO:0000055 ! long microtubules relationship: has_part FYPO:0004862 ! curved microtubules created_by: midori creation_date: 2015-09-23T11:58:15Z [Term] id: FYPO:0004864 name: viable curved vegetative cell with long curved interphase microtubules def: "A cell morphology phenotype in which a vegetatively growing cell is viable, is curved along the long axis, and contains interphase cytoplasmic microtubules that are longer than normal and curved. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "curved viable cell with elongated curved interphase microtubules" EXACT [PomBase:mah] synonym: "viable curved cell with long curved interphase microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "viable curved vegetative cell with long curved cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "viable curved vegetative cell with long curved interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "viable curved vegetative cell with long curved interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002112 ! viable curved vegetative cell is_a: FYPO:0004511 ! long curved interphase microtubules relationship: has_part FYPO:0004511 ! long curved interphase microtubules created_by: midori creation_date: 2015-09-23T12:12:52Z [Term] id: FYPO:0004865 name: long astral microtubules during mitotic anaphase A def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form astral microtubules that are longer than normal during anaphase A. Anaphase A is the stage of mitosis in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [GO:0000091, PomBase:mah] synonym: "elongated astral microtubules during mitotic anaphase A" EXACT [PomBase:mah] synonym: "long astral microtubules during anaphase A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long astral microtubules during mitotic anaphase A during vegetative growth" EXACT [PomBase:mah] synonym: "long cytoplasmic astral microtubules during mitotic anaphase A" EXACT [PomBase:vw] is_a: FYPO:0004612 ! long astral microtubules created_by: midori creation_date: 2015-09-23T12:52:22Z [Term] id: FYPO:0004866 name: enlarged post-anaphase array with increased number of microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the post-anaphase array is larger, and contains more microtubules, than normal." [PMID:18418055, PomBase:mah] synonym: "enlarged PAA with increased number of microtubules" EXACT [PomBase:mah] synonym: "enlarged post-anaphase array with increased number of microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "enlarged post-anaphase array with increased number of microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "microtubules present in increased numbers in enlarged post-anaphase array" EXACT [PomBase:mah] is_a: FYPO:0004317 ! abnormal post-anaphase array morphology created_by: midori creation_date: 2015-09-23T13:07:51Z [Term] id: FYPO:0004867 name: decreased histone H2A phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:mah] synonym: "decreased histone H2A phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H2A phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H2A phosphorylation during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2015-09-23T13:28:58Z [Term] id: FYPO:0004868 name: sensitive to ionizing radiation during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ionizing radiation during G1 phase of the mitotic cell cycle." [PomBase:mah] synonym: "decreased growth during cellular response to ionizing radiation during mitotic G1 phase" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to ionizing radiation during mitotic G1 phase" EXACT [PomBase:mah] synonym: "hypersensitive to ionizing radiation during mitotic G1 phase" EXACT [PomBase:mah] synonym: "sensitive to gamma irradiation during mitotic G1 phase" NARROW [PomBase:al] synonym: "sensitive to gamma radiation during mitotic G1 phase" NARROW [PomBase:al] synonym: "sensitive to ionizing radiation during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "sensitive to ionizing radiation during mitotic G1 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ionizing radiation during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to IR during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000267 ! sensitive to ionizing radiation during vegetative growth created_by: midori creation_date: 2015-09-23T13:31:19Z [Term] id: FYPO:0004869 name: decreased number of Crb2 foci during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Crb2 accumulates is lower than normal during a cellular response to ionizing radiation." [PMID:15226425, PomBase:mah] synonym: "decreased number of Crb2 foci during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Crb2 foci during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased number of Crb2 foci during cellular response to IR" EXACT [PomBase:mah] synonym: "reduced number of Crb2 foci during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-09-23T13:34:33Z [Term] id: FYPO:0004870 name: decreased duration of mitotic G2 DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the duration of mitotic cell cycle arrest or delay due to regulation by the mitotic G2 DNA damage checkpoint is shorter than normal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete." [PomBase:mah] synonym: "decreased duration of G2 DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased duration of mitotic cell cycle G2/M transition DNA damage checkpoint" EXACT [GO:0007095] synonym: "decreased duration of mitotic G2 DNA damage checkpoint activation" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "decreased duration of mitotic G2 DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "reduced duration of mitotic G2 DNA damage checkpoint" EXACT [PomBase:mah] is_a: FYPO:0004373 ! abnormal mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2015-09-23T13:40:23Z [Term] id: FYPO:0004871 name: abnormal 2-oxoglutarate dioxygenase activity def: "A molecular function phenotype in which the observed rate of a 2-oxoglutarate-dependent dioxygenase activity is abnormal." [PomBase:mah] synonym: "abnormal 2-oxoglutarate-dependent dioxygenase activity" EXACT [GO:0016706] synonym: "abnormal oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" EXACT [GO:0016706] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-09-23T13:47:56Z [Term] id: FYPO:0004872 name: abolished 2-oxoglutarate dioxygenase activity def: "A molecular function phenotype in which a 2-oxoglutarate-dependent dioxygenase activity is absent." [PomBase:mah] synonym: "2-oxoglutarate dioxygenase activity abolished" EXACT [PomBase:mah] synonym: "abolished 2-oxoglutarate-dependent dioxygenase activity" EXACT [GO:0016706] synonym: "abolished oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" EXACT [GO:0016706] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004871 ! abnormal 2-oxoglutarate dioxygenase activity created_by: midori creation_date: 2015-09-23T13:48:03Z [Term] id: FYPO:0004873 name: decreased 2-oxoglutarate dioxygenase activity def: "A molecular function phenotype in which a 2-oxoglutarate-dependent dioxygenase activity is decreased." [PomBase:mah] synonym: "decreased 2-oxoglutarate-dependent dioxygenase activity" EXACT [GO:0016706] synonym: "decreased oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" EXACT [GO:0016706] synonym: "reduced 2-oxoglutarate dioxygenase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004871 ! abnormal 2-oxoglutarate dioxygenase activity created_by: midori creation_date: 2015-09-23T13:51:46Z [Term] id: FYPO:0004874 name: decreased glucose consumption def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of glucose consumed by cells in a given time is lower than normal." [PomBase:mah] synonym: "decreased glucose consumption during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased glucose consumption during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glucose uptake" RELATED [PomBase:vw] synonym: "reduced glucose consumption" EXACT [PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2015-09-23T14:08:21Z [Term] id: FYPO:0004875 name: resistance to allyl alcohol def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of allyl alcohol than normal." [PomBase:mah] synonym: "resistance to 3-propenol" EXACT [CHEBI:16605] synonym: "resistance to allyl alcohol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to allyl alcohol during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to allylalcohol" EXACT [PMID:15040954] synonym: "resistant to allyl alcohol" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-09-23T14:14:58Z [Term] id: FYPO:0004876 name: decreased chromatin binding at heat-shock-inducible genes during cellular response to heat shock def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased when the cell is subject to heat shock, at specific genes that are transcriptionally up-regulated during the heat shock." [PomBase:mah] synonym: "decreased chromatin binding at heat shock inducible genes during cellular response to heat shock" EXACT [PomBase:al] synonym: "reduced chromatin binding at heat-shock-inducible genes during cellular response to heat shock" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2015-09-23T15:12:19Z [Term] id: FYPO:0004877 name: decreased chromatin binding at mitotically up-regulated genes def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased at specific genes that are transcriptionally up-regulated during mitosis." [PomBase:mah] synonym: "decreased chromatin binding at mitotically upregulated gene" EXACT [PomBase:al] synonym: "reduced chromatin binding at mitotically up-regulated genes" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2015-09-23T15:17:27Z [Term] id: FYPO:0004878 name: decreased level of mitotically up-regulated gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more mitotically up-regulated RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells)." [PMID:18203864, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of mitotically up-regulated gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of mitotically up-regulated gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of mitotically up-regulated gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased level of mitotically upregulated gene mRNA during vegetative growth" EXACT [PomBase:al] synonym: "decreased mitotically up-regulated gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of mitotically up-regulated gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-09-23T15:19:17Z [Term] id: FYPO:0004879 name: normal chromatin binding at centromere central core def: "A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at the centromere central core." [PomBase:mah] is_a: FYPO:0003086 ! normal chromatin binding created_by: midori creation_date: 2015-09-23T15:21:31Z [Term] id: FYPO:0004880 name: decreased level of lipid metabolism gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more lipid metabolism RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Lipid metabolism RNAs are transcribed from genes whose products are involved in any lipid metabolic process." [PMID:26366556, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of lipid metabolism gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of lipid metabolism gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of lipid metabolism gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased lipid metabolism gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of lipid metabolism gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-10-07T11:07:57Z [Term] id: FYPO:0004881 name: increased duration of mitotic spindle disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle disassembly lasts for a longer time than normal." [GO:0051228, PomBase:mah] synonym: "increased duration of mitotic spindle disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of spindle disassembly during mitotic cell cycle" EXACT [PomBase:mah] synonym: "prolonged mitotic spindle disassembly" EXACT [PomBase:mah] is_a: FYPO:0004621 ! abnormal mitotic spindle disassembly created_by: midori creation_date: 2015-10-07T11:14:44Z [Term] id: FYPO:0004882 name: cytokinesis in presence of assembled mitotic spindle def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis takes place before the mitotic spindle has disassembled. As a result, the contractile ring cuts through the spindle." [PMID:25963819, PomBase:al, PomBase:mah] synonym: "cytokinesis in presence of assembled mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinesis in presence of assembled spindle during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic spindle cut by actomyosin contractile ring" EXACT [PMID:25963819, PomBase:al] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2015-10-07T11:29:36Z [Term] id: FYPO:0004883 name: abnormal protein localization to mitotic spindle midzone def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is abnormal. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1902967, GO:1990023, PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to mitotic spindle midzone" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle midzone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to spindle midzone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002824 ! abnormal protein localization to mitotic spindle created_by: midori creation_date: 2015-10-07T11:33:52Z [Term] id: FYPO:0004884 name: increased duration of protein localization to mitotic spindle midzone def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle midzone for a longer time than normal. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1902967, GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to mitotic spindle midzone" EXACT [PomBase:mah] synonym: "increased duration of protein localization to spindle midzone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to spindle midzone during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein localization to mitotic spindle midzone" EXACT [PomBase:vw] is_a: FYPO:0004883 ! abnormal protein localization to mitotic spindle midzone created_by: midori creation_date: 2015-10-07T11:38:38Z [Term] id: FYPO:0004885 name: abnormal protein localization to nuclear envelope during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the nuclear periphery and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-10-07T11:45:07Z [Term] id: FYPO:0004886 name: abolished protein localization to nuclear envelope during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to nuclear envelope abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth is_a: FYPO:0004885 ! abnormal protein localization to nuclear envelope during vegetative growth created_by: midori creation_date: 2015-10-07T11:45:16Z [Term] id: FYPO:0004887 name: normal protein localization to nuclear envelope during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth is_a: FYPO:0005612 ! normal protein localization to nuclear envelope created_by: midori creation_date: 2015-10-07T11:48:26Z [Term] id: FYPO:0004888 name: abnormal protein localization to telomere def: "A cell phenotype in which the localization of a protein to the telomere of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the telomere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromosome, telomeric region" EXACT [GO:0070198, PomBase:mah] synonym: "abnormal protein localisation to telomere" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromosome, telomeric region" EXACT [GO:0070198, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2015-10-07T11:52:48Z [Term] id: FYPO:0004889 name: abolished protein localization to telomere during meiotic cell cycle def: "A cell phenotype in which the localization of a protein to the telomere of a chromosome does not occur during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromosome, telomeric region, during meiotic cell cycle" EXACT [GO:0070198, PomBase:mah] synonym: "abolished protein localisation to telomere during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein localization to chromosome, telomeric region, during meiotic cell cycle" EXACT [GO:0070198, PomBase:mah] synonym: "protein absent from telomere during meiotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to telomere abolished during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004888 ! abnormal protein localization to telomere created_by: midori creation_date: 2015-10-07T11:53:02Z [Term] id: FYPO:0004890 name: increased telomere-nuclear envelope distance during mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is greater than normal during mitosis." [PMID:19948484, PomBase:mah] synonym: "increased distance between telomeres and nuclear envelope during mitosis" EXACT [PomBase:mah] synonym: "increased telomere-nuclear envelope distance during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased telomere-nuclear envelope distance during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0004790 ! abnormal telomere-nuclear envelope distance during vegetative growth created_by: midori creation_date: 2015-10-07T11:58:23Z [Term] id: FYPO:0004891 name: increased duration of histone H2A phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation lasts for a longer time than normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may persist longer than normal." [PomBase:mah] synonym: "increased duration of histone H2A phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of histone H2A phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged histone H2A phosphorylation during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0000548 ! increased duration of protein modification during vegetative growth is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2015-10-07T12:14:12Z [Term] id: FYPO:0004892 name: normal growth on echinocandin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing an echinocandin." [PomBase:mah] synonym: "normal cell population growth in presence of echinocandin" EXACT [PomBase:mah] synonym: "normal cell population growth on echinocandin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to echinocandin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on echinocandin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-10-07T12:21:40Z [Term] id: FYPO:0004893 name: normal 1,3-beta-D-glucan synthase activity during vegetative growth def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is normal (i.e. indistinguishable from wild type) during the vegetative growth phase of the life cycle." [PMID:11069657, PomBase:mah] synonym: "normal 1,3-beta-D-glucan synthase activity during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002157 ! normal 1,3-beta-D-glucan synthase activity created_by: midori creation_date: 2015-10-07T12:24:38Z [Term] id: FYPO:0004894 name: decreased 1,3-beta-D-glucan synthase activity during sporulation def: "A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is decreased during sporulation." [PMID:11069657, PomBase:mah] synonym: "reduced 1,3-beta-D-glucan synthase activity during sporulation" EXACT [PomBase:mah] is_a: FYPO:0002159 ! decreased 1,3-beta-D-glucan synthase activity created_by: midori creation_date: 2015-10-07T12:28:06Z [Term] id: FYPO:0004895 name: normal rate of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "normal rate of actomyosin contractile ring constriction" EXACT [PomBase:mah] synonym: "normal rate of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of contractile ring contraction" EXACT [PomBase:vw] synonym: "normal rate of cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "normal rate of mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "normal rate of mitotic contractile ring contraction" EXACT [PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-10-07T13:07:01Z [Term] id: FYPO:0004896 name: increased level of generation of precursor metabolites and energy gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more generation of precursor metabolites and energy RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Generation of precursor metabolites and energy RNAs are transcribed from genes whose products are involved in the formation of precursor metabolites and the liberation of energy from these substances." [GO:0006091, PMID:25102102, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased generation of precursor metabolites and energy RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of generation of precursor metabolites and energy gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of generation of precursor metabolites and energy RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of generation of precursor metabolites and energy transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-10-07T13:09:45Z [Term] id: FYPO:0004897 name: decreased level of nitrogen starvation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during nitrogen starvation measured in a cell is lower than normal (i.e. lower than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of cellular response to nitrogen starvation gene mRNA" EXACT [PomBase:al] synonym: "decreased level of nitrogen depletion gene mRNA during vegetative growth" EXACT [PomBase:vw] synonym: "decreased level of nitrogen deprivation gene mRNA during vegetative growth" EXACT [PomBase:vw] synonym: "decreased level of nitrogen starvation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of nitrogen starvation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of nitrogen starvation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased nitrogen starvation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of nitrogen starvation gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-10-07T13:11:57Z [Term] id: FYPO:0004898 name: abnormal pyruvate decarboxylase activity def: "A molecular function phenotype in which the observed rate of pyruvate decarboxylase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-10-07T13:13:39Z [Term] id: FYPO:0004899 name: decreased pyruvate decarboxylase activity during stationary phase def: "A molecular function phenotype in which the observed rate of pyruvate decarboxylase activity is decreased when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "decreased pyruvate decarboxylase activity in stationary phase" EXACT [PomBase:mah] synonym: "reduced pyruvate decarboxylase activity during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004898 ! abnormal pyruvate decarboxylase activity created_by: midori creation_date: 2015-10-07T13:13:52Z [Term] id: FYPO:0004900 name: decreased cellular thiamine level during stationary phase def: "A cell phenotype in which the amount of thiamine measured in a cell is lower than normal when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "decreased cellular thiamine level in stationary phase" EXACT [PomBase:mah] synonym: "decreased cellular vitamin B1 level during stationary phase" EXACT [PomBase:mah] synonym: "decreased thiamine accumulation during stationary phase" RELATED [PomBase:mah] synonym: "reduced cellular thiamine level during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2015-10-07T13:18:02Z [Term] id: FYPO:0004901 name: increased oxygen consumption during stationary phase def: "A cellular process phenotype in which the amount of oxygen consumed by cells in a given time is higher than in wild type when the population in which the cells are found is in stationary phase." [PomBase:mah] comment: Also see 'decreased cellular respiration' (FYPO:0000342). synonym: "increased oxygen consumption in stationary phase" EXACT [PomBase:mah] synonym: "increased oxygen uptake in stationary phase" RELATED [PomBase:vw] is_a: FYPO:0000140 ! cellular metabolism phenotype created_by: midori creation_date: 2015-10-07T13:24:26Z [Term] id: FYPO:0004902 name: curved, elongated, multinucleate multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, has more than one septum and more than one nucleus, and is curved along the long axis." [PMID:25530312, PomBase:mah] synonym: "curved, elongated, multinucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "curved, elongated, multinucleate multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "curved, long, multinucleate multiseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell is_a: FYPO:0005103 ! curved elongated vegetative cell created_by: midori creation_date: 2015-10-07T13:32:10Z [Term] id: FYPO:0004903 name: decreased level of cell separation after cytokinesis gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell separation after cytokinesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cell separation after cytokinesis RNAs are transcribed from genes whose products are involved in cell separation after cytokinesis." [PMID:25530312, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased cell separation after cytokinesis gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of cell separation after cytokinesis gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of cell separation after cytokinesis gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of cell separation after cytokinesis gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased level of cytokinetic cell separation gene mRNA during vegetative growth" RELATED [GO:0000920] synonym: "reduced level of cell separation after cytokinesis gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-10-07T13:37:17Z [Term] id: FYPO:0004904 name: decreased protein localization to centromere central core during vegetative growth alt_id: FYPO:0005224 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome, centric central core" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centromeric central core during vegetative growth" EXACT [GO:0071459, PomBase:mah] synonym: "reduced protein localization to centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at centromere central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-10-07T13:43:10Z [Term] id: FYPO:0004905 name: decreased level of iron homeostasis gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron homeostasis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Iron homeostasis RNAs are transcribed from genes whose products are involved in iron homeostasis." [PMID:23314747, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased iron homeostasis gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of iron homeostasis gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of iron homeostasis gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of iron homeostasis gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of iron homeostasis gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-10-07T13:46:43Z [Term] id: FYPO:0004906 name: decreased level of histone gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Histone RNAs are transcribed from genes encoding histones." [PMID:23314747, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased histone gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of histone gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of histone gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of histone gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of histone gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-10-07T13:47:49Z [Term] id: FYPO:0004907 name: decreased chromatin binding at histone promoter def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased at the promoter regions of genes encoding histones." [PMID:23314747, PomBase:mah] synonym: "decreased chromatin binding at histone gene promoter" EXACT [PomBase:mah] synonym: "reduced chromatin binding at histone promoter" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2015-10-07T13:49:44Z [Term] id: FYPO:0004908 name: abolished L-aminoadipate-semialdehyde dehydrogenase activity def: "A molecular function phenotype in which L-aminoadipate-semialdehyde dehydrogenase activity is absent." [PomBase:mah] synonym: "abolished alpha-aminoadipate reductase activity" EXACT [GO:0004043] synonym: "L-aminoadipate-semialdehyde dehydrogenase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001674 ! abnormal L-aminoadipate-semialdehyde dehydrogenase activity created_by: midori creation_date: 2015-10-07T13:56:20Z [Term] id: FYPO:0004909 name: loss of punctate nuclear protein localization, with protein distributed in nucleus def: "A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed, and the protein is instead distributed throughout the nucleus." [PMID:8937982, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished punctate nuclear protein localization, with protein distributed in nucleus" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localisation, with protein distributed in nucleus" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localization, with protein dispersed through nucleus" EXACT [PomBase:al] synonym: "loss of punctate nuclear protein localization, with protein distributed in nucleus, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "loss of punctate nuclear protein localization, with protein distributed in nucleus, during vegetative growth" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localization, with protein distributed throughout nucleus" EXACT [PomBase:mah] is_a: FYPO:0005863 ! loss of punctate nuclear protein localization created_by: midori creation_date: 2015-10-07T13:58:59Z [Term] id: FYPO:0004910 name: normal punctate nuclear protein localization def: "A cell phenotype in which a protein that is localized normally (i.e. indistinguishably from wild type) to discrete regions in the nucleus, visible as foci or dots by microscopy." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal punctate nuclear protein localisation" EXACT [PomBase:mah] synonym: "normal punctate nuclear protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal punctate nuclear protein localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2015-10-07T14:03:10Z [Term] id: FYPO:0004911 name: abolished glutathione import into vacuole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutathione into the vacuole does not occur." [GO:0071996, PomBase:mah] synonym: "abolished glutathione import into vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished glutathione import into vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "abolished glutathione transmembrane import into vacuole" EXACT [GO:0071996] synonym: "glutathione import into vacuole abolished" EXACT [PomBase:mah] is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2015-10-07T14:13:14Z [Term] id: FYPO:0004912 name: phytochelatin absent from vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in the vacuole is too low to detect." [PomBase:mah] synonym: "cadystin absent from vacuole" EXACT [PMID:2894829] synonym: "phytochelatin absent from vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "phytochelatin absent from vacuole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002722 ! phytochelatin absent from cell is_a: FYPO:0004369 ! decreased vacuolar phytochelatin level created_by: midori creation_date: 2015-10-07T14:15:54Z [Term] id: FYPO:0004913 name: sensitive to nalidixic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nalidixic acid. Cells stop growing (and may die) at a concentration of nalidixic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nalidixic acid" EXACT [PomBase:mah] synonym: "sensitive to nalidixic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nalidixic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-10-07T14:21:34Z [Term] id: FYPO:0004914 name: abnormal telomeric repeat sequence def: "A phenotype in which the sequence of the telomeric repeating unit differs from normal." [PMID:18157152, PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2015-10-07T14:40:51Z [Term] id: FYPO:0004915 name: normal telomeric repeat sequence def: "A phenotype in which the sequence of the telomeric repeating unit is normal (i.e. identical to that found in wild type)." [PMID:18157152, PomBase:mah] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2015-10-07T14:41:39Z [Term] id: FYPO:0004916 name: abnormal regulation of catalytic activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a catalytic activity is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "abnormal regulation of catalytic activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of catalytic activity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000682 ! abnormal regulation of molecular function created_by: midori creation_date: 2015-10-07T14:45:40Z [Term] id: FYPO:0004917 name: decreased positive regulation of protein kinase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of a protein kinase activity occurs to a lower extent than normal." [PMID:11402029, PomBase:mah] synonym: "decreased activation of protein kinase activity" NARROW [PomBase:mah] synonym: "decreased positive regulation of protein kinase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased positive regulation of protein kinase activity during vegetative growth" EXACT [PomBase:mah] synonym: "reduced positive regulation of protein kinase activity" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2015-10-07T14:47:31Z [Term] id: FYPO:0004918 name: abolished positive regulation of protein kinase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of a protein kinase activity does not occur." [PMID:11402029, PomBase:mah] synonym: "abolished activation of protein kinase activity" NARROW [PomBase:mah] synonym: "abolished positive regulation of protein kinase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished positive regulation of protein kinase activity during vegetative growth" EXACT [PomBase:mah] synonym: "positive regulation of protein kinase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2015-10-07T14:48:57Z [Term] id: FYPO:0004919 name: normal regulation of molecular function def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a molecular function is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "normal regulation of molecular function during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal regulation of molecular function during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2015-10-07T14:50:58Z [Term] id: FYPO:0004920 name: normal regulation of catalytic activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a catalytic activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "normal regulation of catalytic activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal regulation of catalytic activity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004919 ! normal regulation of molecular function created_by: midori creation_date: 2015-10-07T14:51:58Z [Term] id: FYPO:0004921 name: normal positive regulation of protein kinase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of a protein kinase activity is normal (i.e. indistinguishable from wild type)." [PMID:11402029, PomBase:mah] synonym: "normal activation of protein kinase activity" NARROW [PomBase:mah] synonym: "normal positive regulation of protein kinase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal positive regulation of protein kinase activity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004920 ! normal regulation of catalytic activity created_by: midori creation_date: 2015-10-07T14:52:11Z [Term] id: FYPO:0004922 name: inviable elongated mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition def: "A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell arrested at G2/M" EXACT [PomBase:jh] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic G2 phase" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic G2/M phase transition arrest" EXACT [PomBase:vw] synonym: "lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in G2-phase with elongated inviable mononucleate aseptate cell" RELATED [PomBase:vw] synonym: "mitotic G2-phase arrested elongated inviable mononucleate aseptate vegetative cell" RELATED [PomBase:mah] is_a: FYPO:0000839 ! inviable elongated mononucleate aseptate cell is_a: FYPO:0005367 ! inviable mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition is_a: FYPO:0007701 ! inviable elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition created_by: midori creation_date: 2015-10-14T10:38:17Z [Term] id: FYPO:0004924 name: normal telomere tethering at nuclear periphery during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitotic telomere tethering at nuclear periphery during vegetative growth" EXACT [GO:0044820] synonym: "normal telomere anchoring at nuclear periphery" EXACT [PomBase:vw] synonym: "normal telomere tethering at nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal telomere tethering to NE during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0008381 ! chromosome region localization phenotype during vegetative growth created_by: midori creation_date: 2015-10-14T11:02:52Z [Term] id: FYPO:0004925 name: irregular ascospore wall def: "A physical cellular phenotype in which the outer surface of the ascospore wall is rougher and less regular than normal." [PMID:20410137, PomBase:mah] synonym: "irregular ascospore wall surface texture" EXACT [PATO:0000700, PomBase:mah] synonym: "irregular spore wall" EXACT [PomBase:mah] synonym: "rough ascospore wall" EXACT [PomBase:mah] is_a: FYPO:0003138 ! abnormal ascospore wall morphology created_by: midori creation_date: 2015-10-14T11:13:34Z [Term] id: FYPO:0004926 name: increased ascospore wall thickness def: "A physical cellular phenotype in which the outer surface of the ascospore wall is thicker than normal." [PMID:20410137, PomBase:mah] synonym: "increased spore wall thickness" EXACT [PomBase:mah] synonym: "thick ascospore wall" EXACT [PomBase:mah] synonym: "thickened spore wall" EXACT [PomBase:mah] is_a: FYPO:0003138 ! abnormal ascospore wall morphology created_by: midori creation_date: 2015-10-14T11:20:44Z [Term] id: FYPO:0004927 name: normal prospore membrane formation def: "A cellular process phenotype in which prospore formation assembly is normal (i.e. indistinguishable from wild type). In prospore formation, the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed." [GO:0032120, PomBase:mah] synonym: "normal ascospore-type prospore membrane assembly" EXACT [GO:0032120] synonym: "normal forespore membrane formation" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2015-10-14T11:32:13Z [Term] id: FYPO:0004928 name: fragmented DNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA is broken into small fragments." [PomBase:mah] comment: Use 'fragmented DNA' (FYPO:0000160) or one of its descendants if DNA was detected using a method that can resolve molecule sizes (e.g. gel electrophoresis) or detect DNA ends (e.g. TUNEL assay). Otherwise, consider using 'fragmented nucleus' (FYPO:0001919) or one of its descendants. synonym: "DNA fragmentation during vegetative growth" EXACT [PomBase:mah] synonym: "fragmented DNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "fragmented nucleus during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000160 ! fragmented DNA is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-10-14T11:34:53Z [Term] id: FYPO:0004929 name: fragmented nucleus during meiotic cell cycle def: "A cell phenotype in which the nucleus is broken into multiple small fragments, smaller than a normal nucleus, during the meiotic cell cycle." [PMID:20410137, PomBase:mah] synonym: "fragmented DNA during meiotic cell cycle" RELATED [PomBase:vw] synonym: "loss of nuclear integrity during meiotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear fragmentation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0006661 ! fragmented nucleus created_by: midori creation_date: 2015-10-14T11:36:50Z [Term] id: FYPO:0004930 name: decreased protein degradation during sporulation def: "A cellular process phenotype in which the occurrence of protein degradation is decreased during sporulation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein catabolic process during sporulation" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during sporulation" EXACT [GO:0030163, PomBase:mah] synonym: "reduced protein degradation during sporulation" EXACT [PomBase:mah] is_a: FYPO:0002797 ! decreased protein degradation relationship: has_output FYPO:0001219 ! increased protein level during cellular response to nitrogen starvation created_by: midori creation_date: 2015-10-14T11:38:12Z [Term] id: FYPO:0004931 name: normal RNA level during sporulation def: "A cell phenotype in which the amount of RNA measured in a cell during sporulation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal cellular RNA level during sporulation" EXACT [PomBase:mah] synonym: "normal mRNA level during sporulation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during sporulation" RELATED [PomBase:mah] synonym: "normal transcript level during sporulation" EXACT [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2015-10-14T11:39:25Z [Term] id: FYPO:0004932 name: increased duration of protein localization to prospore membrane def: "A cell phenotype in which one or more proteins is localized to the prospore membrane for a longer time than normal." [PMID:20410137, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to prospore membrane" EXACT [PomBase:mah] synonym: "increased duration of protein localization to forespore membrane" EXACT [PomBase:mah] synonym: "prolonged protein localization to prospore membrane" EXACT [PomBase:mah] is_a: FYPO:0000677 ! abnormal protein localization to prospore membrane created_by: midori creation_date: 2015-10-14T11:42:16Z [Term] id: FYPO:0004933 name: increased prospore membrane formation def: "A cellular process phenotype in which prospore membrane formation is increased." [PMID:20410137, PomBase:mah] synonym: "increased ascospore-type prospore membrane assembly" EXACT [GO:0032120, PomBase:mah] synonym: "increased forespore membrane formation" EXACT [GO:0032120, PomBase:mah] is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2015-10-14T11:44:45Z [Term] id: FYPO:0004934 name: increased RNA level during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during G1 phase of the mitotic cell cycle is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during mitotic G1 phase" NARROW [PomBase:mah] synonym: "increased RNA accumulation during mitotic G1 phase" RELATED [PomBase:mah] synonym: "increased RNA level during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased RNA level during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during mitotic G1 phase" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-10-14T11:55:22Z [Term] id: FYPO:0004935 name: decreased RNA level during exit from mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during exit from mitosis is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during exit from mitosis" RELATED [PomBase:mah] synonym: "decreased RNA level during exit from mitosis during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased RNA level during exit from mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during mitotic exit" EXACT [GO:0010458] synonym: "decreased RNA level during mitotic M/G1 transition" RELATED [PomBase:mah] synonym: "decreased transcript level during exit from mitosis" EXACT [PomBase:vw] synonym: "reduced RNA level during exit from mitosis" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-10-14T11:58:05Z [Term] id: FYPO:0004936 name: abolished DNA binding at PCB def: "A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter that contains a pombe cell cycle box (PCB) by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [GO:0000978, PMID:12411492, PomBase:mah, SO:0001871] synonym: "abolished DNA binding at pombe cell cycle box" EXACT [PMID:12411492] synonym: "abolished RNA polymerase II proximal promoter sequence-specific DNA binding at PCB" EXACT [GO:0000978] synonym: "abolished RNA polymerase II proximal promoter sequence-specific DNA binding at pombe cell cycle box" EXACT [GO:0000978, PMID:12411492] synonym: "abolished transcription factor binding to PCB-containing promoter region" RELATED [PomBase:al] synonym: "RNA polymerase II proximal promoter sequence-specific DNA binding abolished at PCB" EXACT [PomBase:mah] is_a: FYPO:0002003 ! abolished RNA polymerase II proximal promoter sequence-specific DNA binding created_by: midori creation_date: 2015-10-14T12:11:33Z [Term] id: FYPO:0004937 name: decreased RNA level during meiosis I def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal during the first meiotic nuclear division. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during meiosis I" RELATED [PomBase:mah] synonym: "decreased RNA level during first meiotic nuclear division" EXACT [GO:0007127] synonym: "decreased transcript level during meiosis I" EXACT [PomBase:vw] synonym: "reduced RNA level during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0002959 ! decreased RNA level during meiosis created_by: midori creation_date: 2015-10-14T13:19:59Z [Term] id: FYPO:0004938 name: decreased protein level during meiosis I def: "A cell phenotype in which the amount of protein measured in a cell during the first meiotic nuclear division is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during meiosis I" RELATED [PomBase:mah] synonym: "decreased protein level during first meiotic nuclear division" EXACT [GO:0007127] synonym: "reduced protein level during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2015-10-14T13:23:03Z [Term] id: FYPO:0004939 name: abolished protein phosphorylation during meiotic cell cycle def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein phosphorylation abolished during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0002678 ! abolished protein phosphorylation is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle is_a: FYPO:0006765 ! abnormal protein phosphorylation during meiotic cell cycle created_by: midori creation_date: 2015-10-14T13:28:36Z [Term] id: FYPO:0004940 name: normal growth on chloroacetaldehyde def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chloroacetaldehyde." [PomBase:mah] synonym: "normal cell population growth in presence of chloroacetaldehyde" EXACT [PomBase:mah] synonym: "normal cell population growth on CAA" EXACT [PomBase:vw] synonym: "normal cell population growth on chloroacetaldehyde" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to chloroacetaldehyde" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on chloroacetaldehyde" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-10-14T13:34:10Z [Term] id: FYPO:0004941 name: decreased mannose level in glycoprotein glycan def: "A phenotype in which the glycan moiety of a glycoprotein contains a lower amount of mannose residues than normal. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio." [PMID:11015724, PMID:8782411, PomBase:mah] synonym: "decreased mannose level in glycoprotein oligosaccharide" RELATED [PomBase:vw] synonym: "reduced mannose level in glycoprotein glycan" EXACT [PomBase:mah] is_a: FYPO:0003290 ! abnormal glycoprotein glycan structure created_by: midori creation_date: 2015-10-14T14:05:55Z [Term] id: FYPO:0004942 name: normal galactose:mannose ratio in glycoprotein glycan def: "A phenotype in which the glycan moiety of a glycoprotein contains galactose and mannose residues in a normal (i.e. indistinguishable from wild type) ratio. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages." [PMID:11015724, PMID:8782411, PomBase:mah] synonym: "normal galactose:mannose ratio in glycoprotein oligosaccharide" RELATED [PomBase:vw] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2015-10-14T14:12:30Z [Term] id: FYPO:0004943 name: abnormal mitochondrion def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, morphology, or other physical characteristic of the mitochondrion is abnormal." [PomBase:mah] synonym: "abnormal mitochondria" EXACT [PomBase:mah] synonym: "abnormal mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2015-10-14T14:43:00Z [Term] id: FYPO:0004944 name: decreased mitochondrial membrane potential def: "A physical cellular phenotype in which the mitochondrial membrane potential, i.e. the electric potential existing across the mitochondrial membrane, is smaller than normal." [GO:0051881, PMID:25483891, PomBase:mah] synonym: "decreased mitochondrial membrane polarization" EXACT [PomBase:mah] synonym: "decreased mitochondrial membrane potential during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial membrane potential during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial membrane depolarization" RELATED [PomBase:mah] synonym: "reduced mitochondrial membrane potential" EXACT [PomBase:mah] is_a: FYPO:0004943 ! abnormal mitochondrion created_by: midori creation_date: 2015-10-14T14:48:30Z [Term] id: FYPO:0004945 name: resistance to nigericin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nigericin than normal." [PomBase:mah] synonym: "resistance to nigericin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to nigericin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to nigericin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-10-14T14:57:40Z [Term] id: FYPO:0004946 name: sensitive to potassium ionophore def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more potassium ionophores. A potassium ionophore is any compound that can carry potassium ions through membranes of cells or organelles." [CHEBI:24869, PMID:25483891, PomBase:mah] synonym: "hypersensitive to potassium ionophore" EXACT [PomBase:mah] synonym: "sensitive to potassium ionophore during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to potassium ionophore during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-10-14T14:59:43Z [Term] id: FYPO:0004947 name: normal mitochondrial membrane cardiolipin level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cardiolipin measured in membranes that form the mitochondrial envelope is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of cardiolipin in mitochondrial membrane" EXACT [PomBase:mah] synonym: "normal mitochondrial cardiolipin level" EXACT [PomBase:mah] synonym: "normal mitochondrial envelope cardiolipin level" RELATED [PomBase:mah] synonym: "normal mitochondrial membrane cardiolipin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial membrane cardiolipin level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005590 ! normal cellular cardiolipin level created_by: midori creation_date: 2015-10-14T15:04:50Z [Term] id: FYPO:0004948 name: increased spatial extent of centromeric heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the centromeric region of the chromosome than normal." [PMID:17948055, PomBase:mah] synonym: "increased spatial extent of centromeric heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spatial extent of centromeric heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased spatial extent of centromeric heterochromatin formation" EXACT [PomBase:mah] is_a: FYPO:0007953 ! increased spatial extent of heterochromatin assembly created_by: midori creation_date: 2015-10-14T15:24:09Z [Term] id: FYPO:0004949 name: increased protein phosphorylation during cellular response to rapamycin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to rapamycin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to rapamycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-10-14T15:29:23Z [Term] id: FYPO:0004950 name: elongated vegetative cell with elongated oscillating nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, and the nucleus is longer than normal and undergoes oscillatory movement." [PMID:16611238, PomBase:mah, PomBase:vw] synonym: "elongated cell with elongated oscillating nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "elongated vegetative cell with elongated oscillating nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000832 ! elongated nucleus during vegetative growth is_a: FYPO:0005002 ! elongated vegetative cell with oscillating nucleus relationship: has_part FYPO:0000832 ! elongated nucleus during vegetative growth created_by: midori creation_date: 2015-10-14T15:31:47Z [Term] id: FYPO:0004951 name: increased number of Brc1 foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Brc1 accumulates is greater than normal." [PMID:26368543, PomBase:mah] synonym: "increased number of Brc1 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Brc1 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2015-10-20T13:42:18Z [Term] id: FYPO:0004952 name: incomplete prospore membrane closure def: "A cellular process phenotype in which the prospore membrane begins to form and enclose the nucleus, but the leading edge does not close completely, leaving a gap in the membrane." [PMID:17951524, PomBase:mah] synonym: "incomplete enclosure of nucleus by forespore membrane" RELATED [PomBase:vw] synonym: "incomplete engulfment of nucleus by forespore membrane" RELATED [PomBase:vw] synonym: "incomplete forespore membrane closure" EXACT [PomBase:mah] is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2015-10-20T14:39:12Z [Term] id: FYPO:0004953 name: abnormal prospore membrane def: "A physical cellular phenotype in which the presence, distribution, or morphology of the prospore membrane is abnormal." [PomBase:mah] synonym: "abnormal forespore membrane" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component relationship: output_of FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2015-10-20T14:45:46Z [Term] id: FYPO:0004954 name: excess prospore membrane present def: "A physical cellular phenotype in which cells contain more prospore membrane than normal. Excess prospore membrane may take the form of bubble-like structures continuous with the rest of the membrane." [PMID:17951524, PomBase:mah] synonym: "excess forespore membrane present" EXACT [PomBase:mah] synonym: "forespore membrane bubble formation" RELATED [PMID:17951524] synonym: "prospore membrane present in greater amount" EXACT [PomBase:mah] is_a: FYPO:0004953 ! abnormal prospore membrane created_by: midori creation_date: 2015-10-20T14:48:59Z [Term] id: FYPO:0004955 name: decreased phosphatidylinositol-3-phosphate binding def: "A molecular function phenotype in which occurrence of phosphatidylinositol-3-phosphate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds phosphatidylinositol-3-phosphate less than wild type, or that a mutation in one gene decreases phosphatidylinositol-3-phosphate binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "decreased phosphatidylinositol 3-phosphate binding" EXACT [GO:0032266] synonym: "decreased PtdIns-3-P binding" EXACT [GO:0032266] synonym: "reduced phosphatidylinositol-3-phosphate binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2015-10-20T14:55:26Z [Term] id: FYPO:0004956 name: abnormal mitochondrial RNA 3'-end processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial RNA 3'-end processing is abnormal." [PMID:18304578, PomBase:mah] synonym: "abnormal mitochondrial RNA 3' end processing" EXACT [GO:0000965] synonym: "abnormal mitochondrial RNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial RNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2015-10-20T15:07:40Z [Term] id: FYPO:0004957 name: altered level of substance in mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the mitochondrion differs from normal." [PomBase:mah] synonym: "abnormal level of substance in mitochondrion" EXACT [PomBase:mah] synonym: "abnormal level of substance in mitochondrion during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitochondrial level of substance" EXACT [PomBase:mah] synonym: "altered level of substance in mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered mitochondrial level of substance" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2015-10-20T15:11:13Z [Term] id: FYPO:0004958 name: altered RNA level in mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the mitochondrion differs from normal." [PomBase:mah] synonym: "abnormal mitochondrial RNA level" EXACT [PomBase:mah] synonym: "abnormal mitochondrial RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNA level in mitochondrion" EXACT [PomBase:mah] synonym: "abnormal RNA level in mitochondrion during vegetative growth" EXACT [PomBase:mah] synonym: "altered mitochondrial RNA level" EXACT [PomBase:mah] synonym: "altered RNA level in mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered transcript level in mitochondrion" EXACT [PomBase:mah] is_a: FYPO:0001326 ! altered RNA level during vegetative growth is_a: FYPO:0004957 ! altered level of substance in mitochondrion created_by: midori creation_date: 2015-10-20T15:13:21Z [Term] id: FYPO:0004959 name: normal level of substance in mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the mitochondrion is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of substance in mitochondria" EXACT [PomBase:mah] synonym: "normal level of substance in mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of substance in mitochondrion during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitochondrial level of substance" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2015-10-20T15:15:43Z [Term] id: FYPO:0004960 name: normal mitochondrial RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the mitochondria is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be measured." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mitochondrial RNA accumulation" RELATED [PomBase:mah] synonym: "normal mitochondrial RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitochondrial transcript level" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth is_a: FYPO:0004959 ! normal level of substance in mitochondrion created_by: midori creation_date: 2015-10-20T15:18:08Z [Term] id: FYPO:0004961 name: increased protein localization to chromatin at replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is increased." [PMID:12419251, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at replication origin" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at replication origins during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-10-20T15:23:29Z [Term] id: FYPO:0004962 name: normal protein localization to chromatin at replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is normal (i.e. indistinguishable from wild type)." [PMID:12419251, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at replication origin" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at replication origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at replication origin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-10-20T15:25:58Z [Term] id: FYPO:0004963 name: normal plasma membrane sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the plasma membrane is normal (i.e. indistinguishable from wild type)." [GO:0097036, PMID:18346214, PomBase:mah] synonym: "normal plasma membrane sterol distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal plasma membrane sterol distribution during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007678 ! normal sterol distribution created_by: midori creation_date: 2015-10-20T15:48:38Z [Term] id: FYPO:0004964 name: actin cortical patches present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cortical patches than normal." [PomBase:mah] synonym: "actin cortical patches present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cortical patches present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "actin cortical patches present in reduced numbers" EXACT [PomBase:mah] synonym: "actin patches present in decreased numbers" EXACT [PomBase:mah] synonym: "decreased actin cortical patch formation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased number of actin cortical patches during vegetative growth" EXACT [PomBase:vw] synonym: "F-actin patches present in decreased numbers" EXACT [PomBase:mah] synonym: "fewer actin cortical patches present during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003987 ! abnormal actin cortical patch created_by: midori creation_date: 2015-10-20T15:50:52Z [Term] id: FYPO:0004965 name: inviable swollen pear-shaped vegetative cell def: "A cell morphology phenotype in which a cell is inviable, is shaped in the form of a pear, and has a larger volume than normal, in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell." [PomBase:mah] synonym: "inviable enlarged pear-shaped vegetative cell" RELATED [PomBase:mah] synonym: "inviable enlarged volume pear-shaped vegetative cell" EXACT [PomBase:mah] synonym: "inviable large pear-shaped vegetative cell" RELATED [PomBase:vw] synonym: "inviable swollen ice cream cone-shaped vegetative cell" EXACT [PomBase:mah] synonym: "inviable swollen pear-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable swollen pear-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable, increased pear-shaped vegetative cell size" RELATED [PomBase:vw] synonym: "inviable, increased pear-shaped vegetative cell volume" EXACT [PomBase:mah] synonym: "lethal; swollen pear-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape is_a: FYPO:0002904 ! inviable pear-shaped vegetative cell created_by: midori creation_date: 2015-10-20T15:56:32Z [Term] id: FYPO:0004966 name: increased duration of horsetail movement def: "A cellular process phenotype in which the duration of horsetail movement is longer than normal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] synonym: "increased duration of dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989, PomBase:mah] synonym: "increased duration of horsetail nuclear movement" EXACT [GO:0030989, PomBase:mah] synonym: "prolonged horsetail movement" EXACT [PomBase:mah] is_a: FYPO:0000197 ! abnormal horsetail movement created_by: midori creation_date: 2015-10-20T16:07:06Z [Term] id: FYPO:0004967 name: increased vegetative cell population growth during phosphate starvation def: "A cell growth phenotype in which vegetative cell population growth is increased relative to normal under conditions of phosphate starvation." [PomBase:mah] synonym: "fast vegetative cell population growth during phosphate starvation" NARROW [PomBase:mah] synonym: "increased vegetative cell population growth during phosphate depletion" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during phosphate deprivation" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during phosphate limitation" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth in response to phosphate starvation" EXACT [PomBase:mah] synonym: "resistant to phosphate starvation" RELATED [PomBase:mah] is_a: FYPO:0007685 ! increased vegetative cell population growth during nutrient starvation created_by: midori creation_date: 2015-10-20T16:19:04Z [Term] id: FYPO:0004968 name: decreased vegetative cell population growth during phosphate starvation def: "A cell growth phenotype in which vegetative cell population growth is decreased relative to normal under conditions of phosphate starvation." [PomBase:mah] synonym: "decreased vegetative cell population growth during phosphate depletion" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during phosphate deprivation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during phosphate limitation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth in response to phosphate starvation" EXACT [PomBase:mah] synonym: "reduced vegetative cell population growth during phosphate starvation" EXACT [PomBase:mah] synonym: "sensitive to phosphate starvation" RELATED [PomBase:mah] synonym: "slow vegetative cell population growth during phosphate starvation" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2015-10-20T16:20:51Z [Term] id: FYPO:0004969 name: normal vegetative cell population growth during phosphate starvation def: "A cell growth phenotype in which vegetative cell population growth is cell population growth is normal (i.e. indistinguishable from wild type) under conditions of phosphate starvation." [PomBase:mah] synonym: "normal vegetative cell population growth during phosphate depletion" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth during phosphate deprivation" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth during phosphate limitation" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth in response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2015-10-20T16:22:39Z [Term] id: FYPO:0004970 name: viable elongated vegetative cell during phosphate starvation def: "A cell morphology phenotype in which a vegetative cell is viable and elongated when the cell is subject to phosphate starvation." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated viable vegetative cell during phosphate starvation" EXACT [PomBase:mah] synonym: "viable elongated cell during phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell during phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell created_by: midori creation_date: 2015-10-20T16:24:48Z [Term] id: FYPO:0004971 name: decreased level of stress responsive gene mRNA during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell is lower than normal (i.e. lower than observed in wild-type cells during vegetative growth) during a cellular response to phosphate starvation." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of cellular response to stress gene mRNA during cellular response to phosphate starvation" EXACT [PomBase:al] synonym: "decreased level of stress responsive gene mRNA during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of stress responsive gene mRNA during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of stress responsive gene RNA during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "decreased level of stress responsive gene transcripts during cellular response to phosphate starvation" EXACT [PomBase:vw] synonym: "decreased mRNA level of stress responsive genes during cellular response to phosphate starvation" EXACT [PomBase:al] synonym: "decreased stress responsive gene mRNA accumulation during cellular response to phosphate starvation" RELATED [PomBase:mah] synonym: "reduced level of stress responsive gene mRNA during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0005908 ! decreased level of stress responsive gene mRNA during vegetative growth created_by: midori creation_date: 2015-10-20T16:28:20Z [Term] id: FYPO:0004972 name: actin cortical patches present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cortical patches than normal." [PomBase:mah] synonym: "actin cortical patches present in greater numbers" EXACT [PomBase:mah] synonym: "actin cortical patches present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cortical patches present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "actin patches present in increased numbers" EXACT [PomBase:mah] synonym: "F-actin patches present in increased numbers" EXACT [PomBase:mah] synonym: "increased actin cortical patch formation during vegetative growth" RELATED [PomBase:mah] synonym: "more actin cortical patches present during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003987 ! abnormal actin cortical patch created_by: midori creation_date: 2015-10-20T16:32:05Z [Term] id: FYPO:0004973 name: normal telomere localization def: "A cellular process phenotype in which telomere localization, a process in which a telomere is transported to, and/or maintained in, a specific location, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal telomere localisation" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2015-10-21T11:57:04Z [Term] id: FYPO:0004974 name: normal telomere localization during mitotic interphase def: "A cellular process phenotype in which telomere localization, a process in which a telomere is transported to, and/or maintained in, a specific location, is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal telomere localisation during mitotic interphase" EXACT [PomBase:mah] synonym: "normal telomere localization during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal telomere localization during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal telomere tethering to nuclear periphery during mitotic interphase" EXACT [] is_a: FYPO:0004973 ! normal telomere localization created_by: midori creation_date: 2015-10-21T12:01:08Z [Term] id: FYPO:0004975 name: decreased rate of microtubule depolymerization behind moving spindle pole body def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which depolymerization (i.e. removal of tubulin dimers) of microtubules extending behind a moving spindle pole body occurs at a lower rate, or speed, than normal." [GO:0036078, PMID:16611238, PomBase:mah] synonym: "decreased microtubule shrinkage behind moving spindle pole body" RELATED [PomBase:vw] synonym: "decreased rate of backward-extending microtubule depolymerization" EXACT [PMID:16611238] synonym: "decreased rate of microtubule catastrophe behind moving spindle pole body" RELATED [PomBase:mah] synonym: "decreased rate of microtubule depolymerisation behind moving spindle pole body" EXACT [PomBase:mah] synonym: "decreased rate of microtubule depolymerization behind moving SPB" EXACT [PomBase:mah] synonym: "decreased rate of microtubule depolymerization behind moving spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of microtubule depolymerization behind moving spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "increased microtubule stability behind moving spindle pole body" RELATED [PomBase:vw] synonym: "increased stability of backwards-extending microtubules" RELATED [PMID:16611238, PomBase:vw] synonym: "reduced rate of microtubule depolymerization behind moving spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0000903 ! decreased rate of microtubule depolymerization during vegetative growth created_by: midori creation_date: 2015-10-21T12:20:53Z [Term] id: FYPO:0004976 name: increased rate of microtubule depolymerization ahead of moving spindle pole body def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which depolymerization (i.e. removal of tubulin dimers) of microtubules extending in front of a moving spindle pole body occurs at a greater rate, or speed, than normal." [GO:0036078, PMID:16611238, PomBase:mah] synonym: "decreased microtubule stability ahead of moving spindle pole body" RELATED [PomBase:vw] synonym: "decreased stability of forwards-extending microtubules" RELATED [PMID:16611238, PomBase:vw] synonym: "increased microtubule shrinkage ahead of moving spindle pole body" RELATED [PomBase:vw] synonym: "increased rate of forward-extending microtubule depolymerization" EXACT [PMID:16611238] synonym: "increased rate of microtubule catastrophe ahead of moving spindle pole body" RELATED [PomBase:mah] synonym: "increased rate of microtubule depolymerisation ahead of moving spindle pole body" EXACT [PomBase:mah] synonym: "increased rate of microtubule depolymerization ahead of moving SPB" EXACT [PomBase:mah] synonym: "increased rate of microtubule depolymerization ahead of moving spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of microtubule depolymerization ahead of moving spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003194 ! increased rate of microtubule depolymerization during vegetative growth created_by: midori creation_date: 2015-10-21T12:28:12Z [Term] id: FYPO:0004977 name: increased protein localization to new cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a new cell tip is increased." [PMID:24146635, PomBase:mah] comment: This term can apply to growing or non-growing new cell tips (i.e. before or after NETO), or both. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to new cell tip" EXACT [PomBase:mah] synonym: "increased protein localization to new cell end" EXACT [PomBase:mah] synonym: "increased protein localization to new cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to new cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002852 ! increased protein localization to cell tip during vegetative growth created_by: midori creation_date: 2015-10-21T13:10:25Z [Term] id: FYPO:0004978 name: increased protein localization to new growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a new growing cell tip is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to new growing cell tip" EXACT [GO:0035840, PomBase:mah] synonym: "increased protein localization to new growing cell end" EXACT [PomBase:mah] synonym: "increased protein localization to new growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to new growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004977 ! increased protein localization to new cell tip created_by: midori creation_date: 2015-10-21T13:13:50Z [Term] id: FYPO:0004979 name: elongated monoseptate vegetative cell def: "A cell phenotype in which a cell contains one septum, is longer than normal, and has a greater length:diameter ratio than normal." [PomBase:mah] synonym: "elongated monoseptate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated monoseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "long monoseptate cell" EXACT [PomBase:vw] is_a: FYPO:0004750 ! elongated septated vegetative cell relationship: has_part FYPO:0001225 ! monoseptate created_by: midori creation_date: 2015-10-21T13:30:13Z [Term] id: FYPO:0004980 name: decreased protein localization to eMTOC during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the equatorial microtubule organizing center is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to eMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to eMTOC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to equatorial microtubule organizing center during vegetative growth" EXACT [GO:0000923] synonym: "decreased protein localization to mitotic eMTOC" RELATED [PomBase:vw] synonym: "reduced protein localization to eMTOC during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000933 ! decreased protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0000935 ! abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2015-10-21T13:44:21Z [Term] id: FYPO:0004981 name: normal cellular histone level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histones measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular histone level accumulation" RELATED [PomBase:mah] synonym: "normal cellular histone level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular histone level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of histones in cell" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2015-10-21T13:59:21Z [Term] id: FYPO:0004982 name: increased centromeric transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromeric region are present at greater levels than normal." [PMID:26369364, PomBase:mah] synonym: "increased accumulation of centromeric transcripts" RELATED [PomBase:mah] synonym: "increased accumulation of centromeric transcripts during vegetative growth" RELATED [PomBase:mah] synonym: "increased centromere transcript level" EXACT [PomBase:mah] synonym: "increased centromere-derived transcript level" EXACT [PomBase:mah] synonym: "increased centromeric transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased centromeric transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of centromeric transcripts" EXACT [PomBase:mah] is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2015-10-21T14:03:14Z [Term] id: FYPO:0004983 name: sensitive to vorinostat def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to vorinostat. Cells stop growing (and may die) at a concentration of vorinostat that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to vorinostat" EXACT [PomBase:mah] synonym: "sensitive to N-hydroxy-N'-phenyloctanediamide" EXACT [CHEBI:45716] synonym: "sensitive to SAHA" EXACT [CHEBI:45716] synonym: "sensitive to suberoylanilide hydroxamic acid" EXACT [CHEBI:45716] synonym: "sensitive to vorinostat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to vorinostat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-10-21T14:16:27Z [Term] id: FYPO:0004984 name: decreased chromatin binding at centromere central core def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at the central core of the centromeric regions is decreased." [PomBase:mah] synonym: "reduced chromatin binding at centromere central core" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2015-10-21T14:18:51Z [Term] id: FYPO:0004985 name: entangled telomeres during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that become entwined and resistant to separation." [PMID:21098121, PomBase:mah] synonym: "entangled telomeres during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002254 ! abnormal telomere morphology during vegetative growth is_a: FYPO:0006510 ! abnormal telomere structure created_by: midori creation_date: 2015-10-21T14:31:23Z [Term] id: FYPO:0004986 name: abolished transcription during meiotic cell cycle def: "A cellular process phenotype in which transcription does not occur during the meiotic cell cycle. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "abolished meiotic cell cycle gene expression" RELATED [PomBase:vw] synonym: "transcription abolished during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0002877 ! abolished transcription created_by: midori creation_date: 2015-10-21T14:36:24Z [Term] id: FYPO:0004987 name: sensitive to sunitinib def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sunitinib. Cells stop growing (and may die) at a concentration of sunitinib that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sunitinib" EXACT [PomBase:mah] synonym: "sensitive to sunitinib during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sunitinib during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-10-21T14:39:59Z [Term] id: FYPO:0004988 name: abnormal RNA level oscillation during mitotic cell cycle def: "A gene expression phenotype in which RNA levels that normally vary over the course of the mitotic cell cycle do not vary, or change in a pattern different from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:15302827, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal periodic expression of RNA during mitotic cell cycle" EXACT [PomBase:al] synonym: "abnormal RNA level fluctuation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal transcript level oscillation during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2015-10-21T14:44:33Z [Term] id: FYPO:0004989 name: abnormal meiotic centromere clustering resulting in centromere-spindle pole body colocalization during prophase def: "A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions, such that one or more centromeres is associated with the spindle pole body (SPB) during prophase. Normally, centromeres and SPBs associate after prophase, but not earlier." [PMID:15298676, PomBase:mah] synonym: "abnormal centromere clustering during meiosis resulting in centromere-spindle pole body colocalization during prophase" EXACT [GO:1990571] synonym: "abnormal chromosome retrieval during meiosis resulting in centromere-spindle pole body colocalization during prophase" RELATED [PomBase:vw] synonym: "abnormal kinetochore retrieval during meiosis resulting in centromere-spindle pole body colocalization during prophase" RELATED [PomBase:vw] synonym: "abnormal meiotic centromere clustering resulting in centromere-SPB colocalization during prophase" EXACT [Pombase:al] synonym: "abnormal meiotic centromere clustering resulting in centromere-spindle pole body colocalisation during prophase" EXACT [PomBase:mah] synonym: "abnormal meiotic centromere clustering resulting in centromere-spindle pole body colocalization during meiotic prophase" EXACT [PomBase:mah] synonym: "abnormal meiotic centromere clustering resulting in premature centromere-spindle pole body colocalization" RELATED [PomBase:mah] synonym: "centromeres colocalized with SPB during meiosis" EXACT [PomBase:al] synonym: "centromeres colocalized with SPB during meiotic cell cycle" RELATED [PomBase:al] synonym: "centromeres colocalized with spindle pole body during meiosis" EXACT [PomBase:mah] synonym: "centromeres colocalized with spindle pole body during meiotic cell cycle" RELATED [PomBase:al] is_a: FYPO:0004086 ! abnormal meiotic centromere clustering created_by: midori creation_date: 2015-10-21T15:03:51Z [Term] id: FYPO:0004990 name: G2-exit meiosis with abolished premeiotic DNA replication def: "A cellular process phenotype in which cells in the G2 phase of the mitotic cell cycle undergo meiotic nuclear divisions, and premeiotic DNA replication does not occur. In these cells, sister chromatids precociously segregate at the first meiotic nuclear division. Normally, upon nitrogen starvation cells arrest the mitotic cell in G1 phase, and then proceed into conjugation, premeiotic DNA replication and meiosis." [PMID:15298676, PomBase:mah] synonym: "G2-exit meiotic nuclear division with abolished premeiotic DNA replication" EXACT [GO:0140013] is_a: FYPO:0000052 ! abnormal meiotic cell cycle is_a: FYPO:0002044 ! abolished premeiotic DNA replication relationship: has_part FYPO:0002044 ! abolished premeiotic DNA replication created_by: midori creation_date: 2015-10-21T15:09:51Z [Term] id: FYPO:0004991 name: decreased protein level during meiotic cell cycle def: "A cell phenotype in which the amount of protein measured in a cell during the meiotic cell cycle is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein level during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2015-10-21T15:15:26Z [Term] id: FYPO:0004992 name: decreased protein level during meiotic interphase def: "A cell phenotype in which the amount of protein measured in a cell during interphase of the meiotic cell cycle is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during meiotic interphase" RELATED [PomBase:mah] synonym: "decreased protein level during interphase of meiotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein level during meiotic interphase" EXACT [PomBase:mah] is_a: FYPO:0004991 ! decreased protein level during meiotic cell cycle created_by: midori creation_date: 2015-10-21T15:15:59Z [Term] id: FYPO:0004993 name: normal spore germination frequency def: "A cell population phenotype in which spore germination occurs at a normal (i.e. indistinguishable from wild type) frequency." [PomBase:mah] comment: Note that this phenotype is usually assayed by observing a population of spores and measuring how many germinate. synonym: "normal spore viability" RELATED [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2015-10-21T15:21:40Z [Term] id: FYPO:0004994 name: delayed onset of meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division begins later than normal." [PomBase:mah] synonym: "delayed meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of first meiotic nuclear division" EXACT [GO:0007127] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2015-10-21T15:25:07Z [Term] id: FYPO:0004995 name: normal onset of meiosis I def: "A cellular process phenotype in which the first meiotic nuclear division begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PomBase:mah] synonym: "normal meiosis I progression" RELATED [PomBase:al] synonym: "normal onset of first meiotic nuclear division" EXACT [GO:0007127] synonym: "normal timing of meiosis I" RELATED [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2015-10-21T15:40:41Z [Term] id: FYPO:0004996 name: abnormal protein localization to chromosome def: "A cell phenotype in which the localization of a protein to a specific location on a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at all or part of a chromosome and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromosome" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2015-10-28T11:52:12Z [Term] id: FYPO:0004997 name: normal protein localization to chromosome def: "A cell phenotype in which the localization of a protein to a region in a chromosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromosome" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2015-10-28T11:57:05Z [Term] id: FYPO:0004998 name: decreased duration of horsetail movement def: "A cellular process phenotype in which the duration of horsetail movement is shorter than normal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] synonym: "decreased duration of dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989, PomBase:mah] synonym: "decreased duration of horsetail nuclear movement" EXACT [GO:0030989, PomBase:mah] synonym: "reduced duration of horsetail movement" EXACT [PomBase:mah] is_a: FYPO:0000197 ! abnormal horsetail movement created_by: midori creation_date: 2015-10-28T12:02:40Z [Term] id: FYPO:0004999 name: normal duration of horsetail movement def: "A cellular process phenotype in which the duration of horsetail movement is normal (i.e. indistinguishable from wild type). Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] synonym: "normal duration of dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989] synonym: "normal duration of horsetail nuclear movement" EXACT [GO:0030989] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2015-10-28T12:03:55Z [Term] id: FYPO:0005000 name: protein mislocalized to nucleus during mitotic interphase def: "A cell phenotype in which a protein that is not normally found in the nucleus is observed there during interphase of a mitotic cell cycle." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to nucleus during mitotic interphase" EXACT [PomBase:vw] synonym: "protein mislocalised to nucleus during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalised to nucleus during mitotic interphase" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during interphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2015-10-28T12:17:07Z [Term] id: FYPO:0005001 name: decreased cellular HMW ubiquitin conjugate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polyubiquitin conjugation is lower than normal." [PMID:10082519, PomBase:mah] synonym: "decreased cellular high molecular mass ubiquitin conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular high molecular weight ubiquitin conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular HMW ubiquitin conjugate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular HMW ubiquitin conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular HMW ubiquitin conjugate level" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2015-10-28T13:42:41Z [Term] id: FYPO:0005002 name: elongated vegetative cell with oscillating nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, and the nucleus undergoes oscillatory movement around its normal location." [PMID:16611238, PomBase:mah, PomBase:vw] synonym: "elongated cell with oscillating nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "elongated vegetative cell with oscillating nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2015-10-28T13:52:44Z [Term] id: FYPO:0005003 name: abnormal protein complex composition def: "A physical cellular phenotype in which the composition of a protein complex differs from normal." [PomBase:mah] comment: For consistency with the GO cellular component ontology, 'protein complex' encompasses any complex that contains proteins, including ribonucleoprotein complexes, protein-DNA complexes, etc. synonym: "abnormal protein complex stoichiometry" EXACT [PomBase:mah] synonym: "abnormal protein-containing complex composition" EXACT [GO:0032991] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2015-10-28T14:32:16Z [Term] id: FYPO:0005004 name: decreased protein level in anaphase-promoting complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the anaphase-promoting complex is lower than normal." [PMID:22906049, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the anaphase-promoting complex is decreased, altering the anaphase-promoting complex stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased anaphase-promoting complex protein level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in anaphase-promoting complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level in anaphase-promoting complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in APC" EXACT [PomBase:mah] synonym: "decreased protein level in cyclosome" EXACT [PomBase:mah] synonym: "reduced protein level in anaphase-promoting complex" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0005003 ! abnormal protein complex composition created_by: midori creation_date: 2015-10-28T14:35:10Z [Term] id: FYPO:0005005 name: increased level of hexose transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more hexose transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Hexose transport RNAs are transcribed from genes whose products are involved in transport of six-carbon sugars." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased hexose transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of hexose transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of hexose transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of hexose transport gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0004490 ! increased level of transport gene mRNA during vegetative growth created_by: midori creation_date: 2015-10-28T14:40:32Z [Term] id: FYPO:0005006 name: obsolete normal protein serine phosphorylation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "normal peptidyl-serine phosphorylation" EXACT [GO:0018105] is_obsolete: true replaced_by: FYPO:0004422 created_by: midori creation_date: 2015-10-28T14:44:03Z [Term] id: FYPO:0005007 name: obsolete normal protein serine phosphorylation at RxxS site during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) is normal (i.e. indistinguishable from wild type)." [PMID:22976295, PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "normal peptidyl-serine phosphorylation at RxxS site during vegetative growth" EXACT [GO:0018105] synonym: "normal protein serine phosphorylation at Arg-X-X-Ser site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein serine phosphorylation at arginine-X-X-serine site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein serine phosphorylation at PAS site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein serine phosphorylation at phospho-Akt site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein serine phosphorylation at RxxS site during mitotic cell cycle" RELATED [PomBase:mah] is_obsolete: true replaced_by: FYPO:0004422 created_by: midori creation_date: 2015-10-28T14:44:44Z [Term] id: FYPO:0005008 name: obsolete abolished protein serine phosphorylation at RxxS site during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) does not occur." [PMID:22976295, PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "abolished protein serine phosphorylation at Arg-X-X-Ser site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at arginine-X-X-serine site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at PAS site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at phospho-Akt site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein serine phosphorylation at RxxS site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein serine phosphorylation abolished at RxxS site during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002033 created_by: midori creation_date: 2015-10-28T14:49:04Z [Term] id: FYPO:0005009 name: obsolete decreased protein serine phosphorylation at RxxS site during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) occurs to a lower extent than normal." [PMID:22976295, PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "decreased protein serine phosphorylation at Arg-X-X-Ser site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein serine phosphorylation at arginine-X-X-serine site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein serine phosphorylation at PAS site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein serine phosphorylation at phospho-Akt site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein serine phosphorylation at RxxS site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein serine phosphorylation at RxxS site during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0001838 created_by: midori creation_date: 2015-10-28T14:51:04Z [Term] id: FYPO:0005010 name: obsolete increased protein serine phosphorylation at RxxS site during nitrogen starvation def: "OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues three positions C-terminal to arginine residues (i.e. in Arg-X-X-Ser, or RxxS, sequences) occurs to a greater extent than normal when the cell is subject to nitrogen starvation." [PMID:22976295, PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased protein serine phosphorylation at Arg-X-X-Ser site during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation at arginine-X-X-serine site during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation at PAS site during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation at phospho-Akt site during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation at RxxS site during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation at RxxS site during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased protein serine phosphorylation at RxxS site during nitrogen deprivation" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002681 created_by: midori creation_date: 2015-10-28T14:53:19Z [Term] id: FYPO:0005011 name: decreased histone H4 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H4 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone H4 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002364 ! abnormal histone H4 acetylation during vegetative growth created_by: midori creation_date: 2015-10-28T15:54:46Z [Term] id: FYPO:0005012 name: decreased histone H4-K5 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H4-K5 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4K5 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H4-K5 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0005011 ! decreased histone H4 acetylation during vegetative growth created_by: midori creation_date: 2015-10-28T16:15:42Z [Term] id: FYPO:0005013 name: decreased histone H4-K8 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H4-K8 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4K8 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H4-K8 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0005011 ! decreased histone H4 acetylation during vegetative growth created_by: midori creation_date: 2015-10-28T16:17:02Z [Term] id: FYPO:0005014 name: decreased histone H4-K12 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H4-K12 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4K12 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H4-K12 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0005011 ! decreased histone H4 acetylation during vegetative growth created_by: midori creation_date: 2015-10-28T16:17:24Z [Term] id: FYPO:0005015 name: abnormal rRNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which rRNA modification, the covalent alteration of one or more nucleotides within an rRNA molecule, is abnormal." [GO:0000154, PomBase:mah] synonym: "abnormal rRNA modification during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal rRNA modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2015-10-28T16:28:41Z [Term] id: FYPO:0005016 name: abolished 18S rRNA acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of acetyl groups to residues in an 18S rRNA molecule is abolished." [PMID:25402480, PomBase:mah] comment: At present, the C1297 and C1815 residues are known to be acetylated. synonym: "18S rRNA acetylation abolished" EXACT [PomBase:mah] synonym: "abolished 18S rRNA acetylation at C1297 and C1815" NARROW [PomBase:mah] synonym: "abolished 18S rRNA acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished 18S rRNA acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished 18S rRNA acetylation on C1297 and C1815" EXACT [PomBase:mah] synonym: "abolished 18s rRNA cytidine (1297 and 1815) acetylation" NARROW [PomBase:al] is_a: FYPO:0005015 ! abnormal rRNA modification created_by: midori creation_date: 2015-10-28T16:34:06Z [Term] id: FYPO:0005017 name: abnormal ribosome biogenesis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which ribosome biogenesis is abnormal." [PomBase:mah] synonym: "abnormal ribosome biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ribosome biogenesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2015-10-28T16:40:42Z [Term] id: FYPO:0005018 name: decreased double-stranded DNA binding def: "A molecular function phenotype in which occurrence of double-stranded DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased dsDNA binding" EXACT [GO:0003690] synonym: "reduced double-stranded DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2015-10-28T16:47:25Z [Term] id: FYPO:0005019 name: normal duration of septum assembly def: "A cell cycle phenotype observed in the vegetative growth phase of the life cycle in which the duration of septum assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of division septum assembly" EXACT [GO:0000917] synonym: "normal duration of septation" BROAD [GO:0000917, PomBase:mah] synonym: "normal duration of septum assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal duration of septum assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000673 ! normal septum assembly created_by: midori creation_date: 2015-10-30T15:15:57Z [Term] id: FYPO:0005020 name: normal duration of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "normal duration of actomyosin contractile ring constriction" EXACT [PomBase:vw] synonym: "normal duration of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal duration of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "normal duration of contractile ring contraction" EXACT [PomBase:vw] synonym: "normal duration of cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "normal duration of mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "normal duration of mitotic contractile ring contraction" EXACT [PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-10-30T15:20:42Z [Term] id: FYPO:0005021 name: decreased duration of protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the actomyosin contractile ring for a shorter time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased duration of protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "decreased duration of protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "decreased duration of protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "decreased duration of protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "reduced duration of protein localization to actomyosin contractile ring" EXACT [PomBase:mah] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2015-10-30T15:23:49Z [Term] id: FYPO:0005022 name: decreased rate of protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein to the actomyosin contractile ring is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased rate of protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "decreased rate of protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "decreased rate of protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "decreased rate of protein localization to mitotic contractile ring" EXACT [PomBase:vw] synonym: "decreased rate of protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "reduced rate of protein localization to actomyosin contractile ring" EXACT [PomBase:mah] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2015-10-30T15:25:35Z [Term] id: FYPO:0005023 name: inviable elongated septated mononucleate vegetative cell def: "A cell phenotype in which a cell is inviable, contains one nucleus and one or more septa and is elongated. Cells with this phenotype are inviable, and the nucleus is not in the normal location." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome segregation may be incomplete or entirely abolished. Consider also annotating to 'cut' (FYPO:0003155), 'septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation' (FYPO:0003166), or their descendants, because these phenotypes often co-occur. synonym: "elongated cell with cytokinesis in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "elongated cell with cytokinesis without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "elongated cell with septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "elongated cell with septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "elongated cell with septation without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "inviable elongated cell with premature septation" RELATED [PomBase:al, PomBase:vw] synonym: "inviable elongated septated mononucleate cell" EXACT [PomBase:vw] synonym: "inviable elongated septated mononucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated septated mononucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated septated mononucleate vegetative cell with mislocalized nucleus" EXACT [PomBase:mah] synonym: "inviable septated mononucleate elongated vegetative cell" EXACT [PomBase:vw] synonym: "lethal; elongated septated mononucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002000 ! inviable septated mononucleate vegetative cell is_a: FYPO:0002337 ! inviable elongated mononucleate vegetative cell with mislocalized nucleus is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology is_a: FYPO:0004750 ! elongated septated vegetative cell relationship: has_part FYPO:0001490 ! inviable elongated vegetative cell relationship: output_of FYPO:0000229 ! cut created_by: midori creation_date: 2015-11-03T13:28:15Z [Term] id: FYPO:0005024 name: abnormal mitotic sister chromatid arm separation def: "A cellular process phenotype in which mitotic sister chromatid separation is abnormal along the chromosome arms. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [GO:1990891, PMID:21633354, PomBase:mah] synonym: "abnormal mitotic chromosome arm separation" EXACT [PomBase:mah] synonym: "abnormal sister chromatid arm separation during mitosis" EXACT [PomBase:mah] synonym: "abnormal sister chromatid arm separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal sister chromatid arm separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2015-11-03T14:01:35Z [Term] id: FYPO:0005025 name: abolished mitotic chromosome centromere condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation does not occur in centromeric regions (i.e. adjacent to the kinetochores)." [PMID:21633354, PomBase:mah] synonym: "abolished chromosome centromere condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitotic chromosome centromere condensation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic chromosome condensation at centromere" EXACT [PomBase:mah] synonym: "mitotic chromosome condensation abolished at centromere" EXACT [PomBase:mah] synonym: "mitotic chromosome kinetochore condensation" EXACT [Pombase:vw] is_a: FYPO:0003844 ! abolished mitotic chromosome condensation created_by: midori creation_date: 2015-11-03T14:06:39Z [Term] id: FYPO:0005026 name: increased protein localization to chromatin at chromosome arms def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased along the chromosome arms." [PMID:21633354, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at chromosome arms" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin along chromosome arms" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at chromosome arms during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at chromosome arms during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromosome arm chromatin" EXACT [PomBase:vw] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-03T14:20:15Z [Term] id: FYPO:0005027 name: inviable after spore germination, without cell division, swollen binucleate multiseptate cell with central constriction def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, has a larger diameter and volume than normal, contains two nuclei and more than one septum, and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells." [PomBase:mah] synonym: "inviable after spore germination, binucleate without cell division, swollen with multiple septa" EXACT [PomBase:vw] synonym: "inviable after spore germination, undivided swollen binucleate multiseptate cell with central constriction" EXACT [PomBase:mah] synonym: "inviable after spore germination, without cell division, swollen binucleate multiseptate cell with central constriction, with nuclear division without cytokinesis" EXACT [PomBase:vw] synonym: "inviable after spore germination, without cell division, swollen binucleate multiseptate cell with constricted region at cell division site" EXACT [PomBase:vw] synonym: "inviable after spore germination, without cell division, swollen dumbbell-shaped binucleate multiseptate cell" RELATED [PomBase:mah] synonym: "inviable following spore germination, without cell division, swollen binucleate multiseptate cell with central constriction" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, swollen binucleate multiseptate cell with central constriction" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, swollen binucleate multiseptate cell with central constriction" EXACT [PomBase:mah] is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology is_a: FYPO:0002987 ! inviable after spore germination, without cell division, swollen binucleate cell with central constriction created_by: midori creation_date: 2015-11-03T15:01:01Z [Term] id: FYPO:0005028 name: decreased H4-K20 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased H4K20me2 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H4-K20 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4-K20 dimethylation during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "decreased histone lysine H4-K20 dimethylation during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "reduced histone H4-K20 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: midori creation_date: 2015-11-03T15:18:34Z [Term] id: FYPO:0005029 name: decreased gamma-tubulin complex localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the gamma-tubulin complex to the spindle pole body is decreased." [PomBase:mah] synonym: "decreased gamma-tubulin complex localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "decreased gamma-tubulin complex localization to mitotic SPB" EXACT [PomBase:mah] synonym: "decreased gamma-tubulin complex localization to mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased gamma-tubulin complex localization to mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "reduced gamma-tubulin complex localization to mitotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0004589 ! abnormal gamma-tubulin complex localization to mitotic spindle pole body created_by: midori creation_date: 2015-11-03T15:24:12Z [Term] id: FYPO:0005030 name: increased ribonucleotide incorporation on leading strand def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which more ribonucleotides than normal are incorporated into the leading strand during mitotic DNA replication." [PMID:25664722, PomBase:mah] synonym: "increased ribonucleotide residue incorporation on leading strand" EXACT [PomBase:mah] synonym: "increased rNMP incorporation on leading strand" RELATED [PMID:25664722] synonym: "increased rNTP incorporation on leading strand" RELATED [PMID:25664722] is_a: FYPO:0007680 ! increased ribonucleotide incorporation into DNA created_by: midori creation_date: 2015-11-04T11:33:42Z [Term] id: FYPO:0005031 name: increased ribonucleotide incorporation on lagging strand def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which more ribonucleotides than normal are incorporated into the lagging strand during mitotic DNA replication." [PMID:25664722, PomBase:mah] synonym: "increased ribonucleotide residue incorporation on lagging strand" EXACT [PomBase:mah] synonym: "increased rNMP incorporation on lagging strand" RELATED [PMID:25664722] synonym: "increased rNTP incorporation on lagging strand" RELATED [PMID:25664722] is_a: FYPO:0007680 ! increased ribonucleotide incorporation into DNA created_by: midori creation_date: 2015-11-04T11:35:59Z [Term] id: FYPO:0005032 name: normal mutation rate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a normal (i.e. indistinguishable from wild type) frequency." [PomBase:mah] synonym: "normal mutation rate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mutation rate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2015-11-04T14:04:25Z [Term] id: FYPO:0005033 name: abnormal protein phosphorylation during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein phosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal protein phosphorylation during nitrogen depletion" EXACT [PomBase:mah] synonym: "abnormal protein phosphorylation during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2015-11-10T11:14:54Z [Term] id: FYPO:0005034 name: decreased protein phosphorylation during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased protein phosphorylation during nitrogen deprivation" EXACT [PomBase:vw] synonym: "reduced protein phosphorylation during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002679 ! decreased protein phosphorylation is_a: FYPO:0005033 ! abnormal protein phosphorylation during nitrogen starvation created_by: midori creation_date: 2015-11-10T11:19:01Z [Term] id: FYPO:0005035 name: normal protein phosphorylation during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0004422 ! normal protein phosphorylation created_by: midori creation_date: 2015-11-10T11:23:54Z [Term] id: FYPO:0005036 name: abolished protein phosphorylation during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during nitrogen deprivation" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002678 ! abolished protein phosphorylation is_a: FYPO:0005033 ! abnormal protein phosphorylation during nitrogen starvation created_by: midori creation_date: 2015-11-10T11:24:50Z [Term] id: FYPO:0005037 name: normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [GO:0071620, PMID:22144909, PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen deprivation" EXACT [PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II CTD serine 5 residues during nitrogen depletion" EXACT [PomBase:mah] synonym: "reduced phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0005035 ! normal protein phosphorylation during nitrogen starvation created_by: midori creation_date: 2015-11-10T11:39:25Z [Term] id: FYPO:0005038 name: abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II does not occur when the cell is subject to nitrogen starvation." [GO:0071619, PMID:22144909, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen deprivation" EXACT [PomBase:mah] synonym: "phosphorylation of RNA polymerase II CTD serine 2 residues abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0005036 ! abolished protein phosphorylation during nitrogen starvation is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2015-11-10T11:41:45Z [Term] id: FYPO:0005039 name: decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [GO:0071619, PMID:22144909, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced phosphorylation of RNA polymerase II CTD serine 2 residues during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0005034 ! decreased protein phosphorylation during nitrogen starvation is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2015-11-10T11:44:30Z [Term] id: FYPO:0005040 name: normal phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation def: "A cellular process phenotype in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [GO:0071620, PMID:22144909, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen deprivation" EXACT [PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II CTD serine 2 residues during nitrogen depletion" EXACT [PomBase:mah] is_a: FYPO:0005035 ! normal protein phosphorylation during nitrogen starvation created_by: midori creation_date: 2015-11-10T11:46:07Z [Term] id: FYPO:0005041 name: increased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a greater extent than normal." [GO:0071619, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phosphorylation of RNA polymerase II CTD serine 2 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2015-11-10T11:46:50Z [Term] id: FYPO:0005042 name: normal protein localization to kinetochore def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2015-11-10T11:59:26Z [Term] id: FYPO:0005043 name: abnormal regulation of translation in response to UV def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to ultraviolet light is abnormal." [PMID:17369398, PomBase:mah] synonym: "abnormal regulation of translation in response to ultraviolet light" EXACT [PomBase:mah] synonym: "abnormal regulation of translation in response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of translation in response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005044 ! translation regulation phenotype during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2015-11-10T12:12:56Z [Term] id: FYPO:0005044 name: translation regulation phenotype during vegetative growth def: "A gene expression phenotype that affects the regulation of translation in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast translation regulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "translation regulation phenotype during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000289 ! translation regulation phenotype is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth created_by: midori creation_date: 2015-11-10T12:14:24Z [Term] id: FYPO:0005045 name: abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation." [PMID:20935472, PomBase:mah] synonym: "abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sister chromatid segregation with lagging chromosomes and decreased rate of spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lagging mitotic chromosomes with decreased rate of mitotic spindle elongation" EXACT [PomBase:mah] synonym: "lagging mitotic chromosomes with decreased spindle elongation rate" EXACT [PomBase:al] synonym: "lagging mitotic sister chromatids, with decreased rate of mitotic spindle elongation" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0003268 ! decreased rate of mitotic spindle elongation relationship: has_part FYPO:0000228 ! lagging mitotic chromosomes relationship: has_part FYPO:0003268 ! decreased rate of mitotic spindle elongation created_by: midori creation_date: 2015-11-10T12:56:15Z [Term] id: FYPO:0005046 name: abnormal mitotic sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation. Although one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated, mitotic sister chromatid segregation does eventually go on to complete separation of chromosomes." [PMID:20935472, PomBase:mah] synonym: "abnormal mitotic sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lagging mitotic chromosomes, with complete sister chromatid separation and decreased spindle elongation rate" EXACT [PomBase:al] synonym: "lagging mitotic chromosomes, with complete sister chromatid separation, and decreased rate of mitotic spindle elongation" EXACT [PomBase:mah] synonym: "lagging mitotic sister chromatids, with complete sister chromatid separation, and decreased rate of mitotic spindle elongation" EXACT [PomBase:mah] is_a: FYPO:0003268 ! decreased rate of mitotic spindle elongation is_a: FYPO:0004101 ! lagging mitotic chromosomes, with complete sister chromatid separation relationship: has_part FYPO:0003268 ! decreased rate of mitotic spindle elongation created_by: midori creation_date: 2015-11-10T13:05:16Z [Term] id: FYPO:0005047 name: decreased protein localization to chromatin at RNA polymerase II promoter during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at RNA polymerase II promoters is decreased." [PMID:20605454, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at RNA polymerase II promoter during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at RNA pol II promoter during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at RNA polymerase II promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to chromatin at RNA polymerase II promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004161 ! decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth created_by: midori creation_date: 2015-11-10T13:14:14Z [Term] id: FYPO:0005048 name: increased protein localization to chromatin at RNA polymerase II promoter during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at RNA polymerase II promoters is increased." [PMID:20605454, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at RNA polymerase II promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at RNA pol II promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at RNA polymerase II promoter during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-10T13:19:32Z [Term] id: FYPO:0005049 name: decreased protein localization to chromatin at RNA polymerase II promoter during nitrogen starvation def: "A cell phenotype in which the localization of a protein to chromatin at RNA polymerase II promoters is decreased when the cell is subject to nitrogen starvation." [PMID:20605454, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at RNA polymerase II promoter during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at RNA pol II promoter during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at RNA polymerase II promoter during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at RNA polymerase II promoter nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0005051 ! decreased protein localization to chromatin at RNA polymerase II-regulated genes during nitrogen starvation is_a: FYPO:0006631 ! decreased protein localization to chromatin created_by: midori creation_date: 2015-11-10T13:22:53Z [Term] id: FYPO:0005050 name: decreased chromatin binding during cellular response to nitrogen starvation def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased when the cell is subject to nitrogen starvation. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "decreased chromatin binding during cellular response to nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased chromatin binding during cellular response to nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced chromatin binding during cellular response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2015-11-10T13:26:55Z [Term] id: FYPO:0005051 name: decreased protein localization to chromatin at RNA polymerase II-regulated genes during nitrogen starvation def: "A cell phenotype in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is decreased when the cell is subject to nitrogen starvation." [PMID:20605454, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at RNA polymerase II-regulated genes during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at polymerase II regulated genes during nitrogen starvation" EXACT [PomBase:vw] synonym: "decreased protein localization to chromatin at RNA polymerase II-regulated genes during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at RNA polymerase II-regulated genes during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at RNA polymerase II-regulated genes during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001679 ! abnormal protein localization to chromatin created_by: midori creation_date: 2015-11-10T13:29:06Z [Term] id: FYPO:0005052 name: obsolete decreased production of siRNA involved in chromatin silencing by small RNA def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs), as part of chromatin silencing by small RNA, is decreased." [GO:0070919, PomBase:mah] comment: This term was made obsolete because the observations can be adequately represented by RNA level terms. synonym: "decreased chromatin silencing by small RNA, production of guide RNAs" EXACT [GO:0070919] synonym: "decreased chromatin silencing by small RNA, production of siRNA" EXACT [GO:0070919] synonym: "decreased production of guide RNAs involved in chromatin silencing by small RNA" EXACT [GO:0070919] synonym: "decreased production of siRNA involved in chromatin silencing by small RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased production of siRNA involved in chromatin silencing by small RNA during vegetative growth" EXACT [PomBase:mah] synonym: "reduced production of siRNA involved in chromatin silencing by small RNA" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2015-11-10T13:38:37Z [Term] id: FYPO:0005053 name: abnormal RITS complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RITS complex assembly is abnormal." [PomBase:mah] synonym: "abnormal RITS complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RITS complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2015-11-10T13:42:36Z [Term] id: FYPO:0005054 name: normal cell cycle regulation during cellular response to latrunculin A def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to latrunculin A is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to latrunculin A." [PMID:15537703, PomBase:mah] synonym: "normal cell cycle delay following latrunculin A exposure" NARROW [PomBase:al] synonym: "normal cell cycle regulation during cellular response to LatA" EXACT [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to latrunculin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to latrunculin A during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell cycle regulation in response to latrunculin A" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to latrunculin A" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2015-11-10T14:00:53Z [Term] id: FYPO:0005055 name: binucleate multiseptate cell, septa grouped def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two and more than one septum, and the septa are grouped together between the two compartments, one or more of which may contain multiple nuclei." [PomBase:mah] synonym: "binucleate multiseptate cell, septa grouped during mitotic cell cycle" RELATED [PomBase:mah] synonym: "binucleate multiseptate cell, septa grouped during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001223 ! binucleate multiseptate vegetative cell is_a: FYPO:0001254 ! multinucleate multiseptate vegetative cell, septa grouped created_by: midori creation_date: 2015-11-18T13:52:17Z [Term] id: FYPO:0005057 name: abolished meiotic DNA double-strand break clipping def: "A cellular process phenotype in which meiotic DNA double-strand break clipping does not occur. Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis." [GO:1990898, PMID:26130711, PomBase:mah] synonym: "meiotic DNA double-strand break clipping abolished" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2015-11-18T14:12:20Z [Term] id: FYPO:0005058 name: decreased meiotic DNA double-strand break clipping def: "A cellular process phenotype in which meiotic DNA double-strand break clipping is decreased. Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis." [GO:1990898, PMID:26130711, PomBase:mah] synonym: "reduced meiotic DNA double-strand break clipping" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2015-11-18T14:13:45Z [Term] id: FYPO:0005059 name: decreased meiotic DNA double-strand break resection def: "A cellular process phenotype in which meiotic DNA double-strand break resection is decreased. Meiotic DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed." [GO:1990899, PMID:26130711, PomBase:mah] synonym: "decreased meiotic DNA double-strand break resectioning" EXACT [PomBase:mah] synonym: "reduced meiotic DNA double-strand break resection" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2015-11-18T14:22:37Z [Term] id: FYPO:0005060 name: normal meiotic DNA double-strand break resection def: "A cellular process phenotype in which meiotic DNA double-strand break resection is normal (i.e. indistinguishable from wild type). Meiotic DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed." [GO:1990899, PMID:26130711, PomBase:mah] synonym: "normal meiotic DNA double-strand break resectioning" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2015-11-18T14:25:37Z [Term] id: FYPO:0005061 name: normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type)." [GO:0071620, PMID:17502918, PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II CTD serine 5 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-11-18T14:33:49Z [Term] id: FYPO:0005062 name: increased histone H3-K4 methylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 4 of histone H3 in telomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K4 methylation at telomere" EXACT [GO:0051568, PomBase:mah] synonym: "increased histone H3-K4 methylation at telomere during mitotic cell cycle during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K4 methylation at telomeric region" EXACT [PomBase:vw] synonym: "increased histone H3K4 methylation at telomere" EXACT [PomBase:vw] synonym: "increased histone H3K4me at telomere" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 methylation at telomere" EXACT [GO:0051568, PomBase:mah] is_a: FYPO:0000869 ! increased histone methylation during vegetative growth is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth is_a: FYPO:0007375 ! abnormal histone methylation at telomere during vegetative growth created_by: midori creation_date: 2015-11-18T15:04:48Z [Term] id: FYPO:0005063 name: increased histone H3-K4 methylation at mating type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 4 of histone H3 at the mating type locus occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K4 methylation at mating type locus during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "increased histone H3-K4 methylation at mating type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K4 methylation at mating type locus during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K4me at mating type locus during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 methylation at mating type locus during vegetative growth" EXACT [GO:0051568, PomBase:mah] is_a: FYPO:0000869 ! increased histone methylation during vegetative growth is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2015-11-18T15:10:19Z [Term] id: FYPO:0005064 name: increased histone H3-K9 methylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in telomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation at telomere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 methylation at telomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9 methylation at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me at telomere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at telomere during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth is_a: FYPO:0007375 ! abnormal histone methylation at telomere during vegetative growth created_by: midori creation_date: 2015-11-18T15:11:46Z [Term] id: FYPO:0005065 name: increased histone H3-K9 methylation at mating type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at the mating type locus occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation at mating type locus during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at mating type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 methylation at mating type locus during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me at mating type locus during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at mating type locus during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth is_a: FYPO:0007373 ! abnormal histone methylation at silent mating-type cassette during vegetative growth created_by: midori creation_date: 2015-11-18T15:13:54Z [Term] id: FYPO:0005066 name: increased histone H3-K9 methylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation at centromere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 methylation at centromeric region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9 methylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me at centromere during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at centromere during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth is_a: FYPO:0007374 ! abnormal histone methylation at centromere during vegetative growth created_by: midori creation_date: 2015-11-18T15:14:38Z [Term] id: FYPO:0005067 name: sensitive to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane (DETA NONOate). Cells stop growing (and may die) at a concentration of 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane" EXACT [PomBase:mah] synonym: "sensitive to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DETA NONOate" EXACT [CHEBI:50154] synonym: "sensitive to diethylenetriamine NONOate" EXACT [CHEBI:50154] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-11-18T15:27:49Z [Term] id: FYPO:0005068 name: increased number of double-strand break sites during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of double-strand breaks in DNA is greater than normal during S phase of the mitotic cell cycle." [PMID:18180284, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad52 foci during vegetative growth' (FYPO:0000972). synonym: "accumulation of DNA damage foci during mitotic S phase" RELATED [PomBase:mah] synonym: "accumulation of double-strand break sites during mitotic S phase" EXACT [PomBase:mah] synonym: "increased number of DNA damage foci during mitotic S phase" RELATED [PomBase:mah] synonym: "increased number of double-strand break sites during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of double-strand break sites during S phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000455 ! increased number of double-strand break sites during vegetative growth created_by: midori creation_date: 2015-11-18T15:44:28Z [Term] id: FYPO:0005069 name: unequal mitotic sister chromatid segregation following normal mitosis def: "A cellular process phenotype in which mitotic sister chromatid segregation fails to separate chromosomes into two equal masses after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. Unequal mitotic sister chromatid separation may be complete, with two distinct unequal DNA masses located at or near the ends of an elongated mitotic spindle, or incomplete." [PMID:18180284, PomBase:mah] comment: This phenotype affects the second round of mitosis to take place after a mutation exerts its effect. For example, if a conditional mutant is shifted to restrictive conditions in G1 or S phase and the first mitosis thereafter is normal, but the second is not (even if cells are returned to permissive conditions), this term is applicable. synonym: "mitotic chromosome nondisjunction following normal mitosis" EXACT [PomBase:mah] synonym: "unequal mitotic chromosome segregation following normal mitosis" EXACT [PomBase:mah] synonym: "unequal mitotic sister chromatid segregation during vegetative growth following normal mitosis" EXACT [PomBase:mah] synonym: "unequal mitotic sister chromatid separation following normal mitosis" RELATED [PomBase:mah] synonym: "unequal sister chromatid segregation following normal mitosis during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003241 ! unequal mitotic sister chromatid segregation is_a: FYPO:0004588 ! abnormal mitosis following normal mitosis created_by: midori creation_date: 2015-11-18T15:53:46Z [Term] id: FYPO:0005070 name: obsolete cut with abolished mitotic sister chromatid separation, with mononucleate and anucleate compartment formation def: "OBSOLETE. An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abolished mitotic sister chromatid separation, producing inviable daughter cells, and in which the septum forms in a position that partitions the nucleus into one compartment. Cell separation may or may not be completed." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because its name and text definition were contradictory (the definition excludes the distinguishing features of "cut"). synonym: "cut with abolished mitotic sister chromatid separation and anucleate cell formation" EXACT [PomBase:mah] synonym: "cut with abolished mitotic sister chromatid separation, with mononucleate and anucleate compartment formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut with abolished mitotic sister chromatid separation, with mononucleate and anucleate compartment formation during vegetative growth" EXACT [PomBase:mah] synonym: "monoseptate vegetative cell with mononucleate and anucleate compartments following abolished mitotic sister chromatid separation" EXACT [PomBase:mah] synonym: "septation following abolished mitotic sister chromatid separation, with mononucleate and anucleate compartment formation" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2015-11-18T16:08:59Z [Term] id: FYPO:0005071 name: increased chromatin silencing at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is increased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). synonym: "increased chromatin silencing at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased heterochromatin silencing at centromere" RELATED [PomBase:mah] is_a: FYPO:0000146 ! abnormal chromatin silencing at centromere is_a: FYPO:0004540 ! increased chromatin silencing created_by: midori creation_date: 2015-11-18T16:17:12Z [Term] id: FYPO:0005072 name: normal protein localization to centromeric chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is normal (i.e. indistinguishable from wild type." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to centromeric chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to centromeric chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at centromere" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth is_a: FYPO:0002574 ! normal protein localization to centromere during vegetative growth creation_date: 2015-11-18T16:44:29Z [Term] id: FYPO:0005073 name: decreased mitotic chromosome arm condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation occurs to a lower extent than normal along the chromosome arms." [GO:1990892, PMID:21633354, PomBase:mah] synonym: "decreased chromosome arm condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic chromosome arm chromatin condensation" EXACT [GO:1990892] synonym: "decreased mitotic chromosome arm condensation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic chromosome condensation along chromosome arms" EXACT [PomBase:vw] synonym: "reduced mitotic chromosome arm condensation" EXACT [PomBase:mah] is_a: FYPO:0003286 ! decreased mitotic chromosome condensation created_by: midori creation_date: 2015-11-18T16:46:24Z [Term] id: FYPO:0005074 name: normal protein level in anaphase-promoting complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the anaphase-promoting complex is normal (i.e. indistinguishable from wild type)." [PMID:9264466, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein level in APC" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2015-11-18T16:54:49Z [Term] id: FYPO:0005075 name: decreased anaphase-promoting complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of anaphase-promoting complex assembly is decreased." [PomBase:mah] synonym: "decreased anaphase-promoting complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased anaphase-promoting complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased APC assembly" EXACT [PomBase:mah] synonym: "reduced anaphase-promoting complex formation" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2015-11-23T13:56:53Z [Term] id: FYPO:0005077 name: elongated cell during glucose starvation def: "A cell morphology phenotype in which a cell becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to glucose starvation." [PMID:17179073, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "cell morphology, elongated cell during glucose starvation" EXACT [PomBase:mah] synonym: "elongated cell during glucose depletion" EXACT [PomBase:vw] synonym: "elongated cell during glucose deprivation" EXACT [PomBase:vw] synonym: "long cell during glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0000017 ! elongated cell created_by: midori creation_date: 2015-11-23T14:05:29Z [Term] id: FYPO:0005078 name: sensitive to canavanine and rapamycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of canavanine and rapamycin. Cells stop growing (and may die) at concentrations of canavanine and rapamycin that allows wild type cells to grow." [PMID:17179073, PomBase:mah] synonym: "hypersensitive to canavanine and rapamycin" EXACT [PomBase:mah] synonym: "sensitive to canavanine and rapamycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to canavanine and rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to canavanine and rapamycin in combination" EXACT [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2015-11-23T14:06:56Z [Term] id: FYPO:0005079 name: normal protein localization to chromatin at centromere central core def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at centromere central core" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromeric central core" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:30:07Z [Term] id: FYPO:0005080 name: normal protein localization to heterochromatin at centromere inner repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at centromere inner repeat" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromere imr" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008154 ! normal protein localization to centromeric heterochromatin created_by: midori creation_date: 2015-11-23T14:44:00Z [Term] id: FYPO:0005082 name: normal protein localization to chromatin at long terminal repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at long terminal repeat regions is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at long terminal repeat" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at long terminal repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at long terminal repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at LTR" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:46:32Z [Term] id: FYPO:0005083 name: normal protein localization to chromatin at ncRNA gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA (ncRNA) genes is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at ncRNA gene" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at ncRNA gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at ncRNA gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:47:57Z [Term] id: FYPO:0005084 name: normal protein localization to chromatin at rRNA gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal RNA (rRNA) genes is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at rRNA gene" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at rDNA" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at ribosomal DNA" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at rRNA gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at rRNA gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:48:53Z [Term] id: FYPO:0005085 name: normal protein localization to chromatin at snRNA gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at small nuclear RNA (snRNA) genes is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at snRNA gene" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at snRNA gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at snRNA gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:50:07Z [Term] id: FYPO:0005086 name: normal protein localization to chromatin at snoRNA gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at small nucleolar RNA (snoRNA) genes is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at snoRNA gene" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at snoRNA gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at snoRNA gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:51:05Z [Term] id: FYPO:0005087 name: normal protein localization to chromatin at tRNA gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at transfer RNA (tRNA) genes is normal (i.e. indistinguishable from wild type)." [PMID:21151114, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at tRNA gene" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at tDNA" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at tRNA gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at tRNA gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-11-23T14:51:50Z [Term] id: FYPO:0005088 name: inviable after spore germination, multiple cell divisions, binucleate septated cell def: "A phenotype in which a spore germinates to produce a cell that contains two nuclei and one or more septa, and undergoes two or more rounds of cell division, and then dies." [PMID:15829570, PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, binucleate septated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, binucleate septated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, binucleate septated cell" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2015-11-23T15:01:54Z [Term] id: FYPO:0005089 name: abolished RNA polymerase II carboxy-terminal domain kinase activity def: "A molecular function phenotype in which RNA polymerase II carboxy-terminal domain kinase activity is absent." [PomBase:mah] synonym: "RNA polymerase II carboxy-terminal domain kinase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2015-11-23T15:04:10Z [Term] id: FYPO:0005090 name: decreased level of cytokinesis gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cytokinesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cytokinesis RNAs are transcribed from genes whose products are involved in one or more cytokinetic processes." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased cytokinesis gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of cytokinesis gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of cytokinesis gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of cytokinesis gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of cytokinesis gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2015-11-23T15:12:30Z [Term] id: FYPO:0005091 name: normal DNA binding at PCB def: "A molecular function phenotype in which occurrence of DNA binding at a pombe cell cycle box (PCB) by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal DNA binding at pombe cell cycle box" EXACT [PomBase:mah] synonym: "normal PCB DNA binding" EXACT [PomBase:mah] synonym: "normal RNA polymerase II proximal promoter sequence-specific DNA binding at PCB" EXACT [GO:0000978] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2015-11-23T15:31:42Z [Term] id: FYPO:0005092 name: inviable after spore germination, multiple cell divisions, swollen, elongated pear-shaped cell def: "A phenotype in which a spore germinates to produce a cell that has a greater length, diameter, and volume than normal, is shaped in the form of a pear, and undergoes two or more rounds of cell division and then dies. In a pear-shaped cell, one end is rounded, while the other resembles an end of a normal rod-shaped cell." [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, swollen, elongated pear-shaped cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, swollen, elongated pear-shaped cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, swollen, elongated pear-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0004965 ! inviable swollen pear-shaped vegetative cell is_a: FYPO:0007140 ! inviable after spore germination, multiple cell divisions, swollen, elongated cell created_by: midori creation_date: 2015-12-01T14:16:08Z [Term] id: FYPO:0005093 name: decreased duration of protein phosphorylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is shorter than normal during a cellular response to hydroxyurea. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased duration of protein phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased duration of protein phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of protein phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "reduced duration of protein phosphorylation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2015-12-01T14:22:32Z [Term] id: FYPO:0005094 name: decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the S-phase DNA damage checkpoint is lower than in wild type during a cellular response to hydroxyurea." [PomBase:mah] synonym: "decreased duration of intra-S DNA damage checkpoint during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased duration of mitotic S-phase DNA damage checkpoint during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint activation during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "premature S-phase DNA damage checkpoint deactivation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "reduced duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001933 ! abnormal mitotic cell cycle regulation during cellular response to hydroxyurea is_a: FYPO:0004371 ! decreased duration of S-phase DNA damage checkpoint created_by: midori creation_date: 2015-12-01T14:27:18Z [Term] id: FYPO:0005095 name: abolished protein localization to chromatin at replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at replication origin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at replication origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to chromatin at replication origin during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-12-01T14:29:04Z [Term] id: FYPO:0005096 name: increased duration of protein localization to mitotic spindle pole body during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle pole body for a longer time than normal during anaphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to mitotic spindle pole body during anaphase" EXACT [PomBase:mah] synonym: "increased duration of protein localization to mitotic SPB during anaphase" EXACT [PomBase:mah] synonym: "increased duration of protein localization to spindle pole body during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to spindle pole body during mitotic anaphase" EXACT [PomBase:mah] synonym: "prolonged protein localization to mitotic spindle pole body during anaphase" EXACT [PomBase:vw] is_a: FYPO:0001837 ! increased duration of protein localization to mitotic spindle pole body created_by: midori creation_date: 2015-12-01T14:43:29Z [Term] id: FYPO:0005097 name: abnormal cell cycle arrest in mitotic G1 phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested during G1 phase. Arrest may either occur under conditions where arrest is not a normal occurrence, or may progress differently from normal under conditions where arrest normally does take place." [PomBase:mah] comment: Use this term for terminal arrest. If arrest is transient, consider using 'increased duration of mitotic cell cycle phase' (FYPO:0001069) or one of its more specific descendants. synonym: "abnormal cell cycle arrest in G1 phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000445 ! cell cycle arrest in mitotic G1 phase is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2015-12-01T14:50:25Z [Term] id: FYPO:0005098 name: abnormal poly(A) polymerase activity def: "A molecular function phenotype in which the observed rate of poly(A) polymerase activity (EC name polynucleotide adenylyltransferase activity) is abnormal." [PomBase:mah] synonym: "abnormal PAP activity" EXACT [PMID:24322298] synonym: "abnormal polynucleotide adenylyltransferase activity" EXACT [EC:2.7.7.19, GO:0004652] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-12-01T15:02:14Z [Term] id: FYPO:0005099 name: decreased poly(A) polymerase activity def: "A molecular function phenotype in which the observed rate of poly(A) polymerase activity (EC name polynucleotide adenylyltransferase activity) is decreased." [PomBase:mah] synonym: "decreased PAP activity" EXACT [PMID:24322298] synonym: "decreased polynucleotide adenylyltransferase activity" EXACT [EC:2.7.7.19, GO:0004652] synonym: "reduced poly(A) polymerase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005098 ! abnormal poly(A) polymerase activity created_by: midori creation_date: 2015-12-01T15:02:21Z [Term] id: FYPO:0005100 name: normal poly(U) polymerase activity def: "A molecular function phenotype in which the observed rate of poly(U) polymerase activity (EC name RNA uridylyltransferase activity) is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal PUP activity" EXACT [PMID:24322298] synonym: "normal RNA uridylyltransferase activity" EXACT [EC:2.7.7.52, GO:0050265] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2015-12-01T15:07:16Z [Term] id: FYPO:0005101 name: decreased poly(U) RNA binding def: "A molecular function phenotype in which an interaction between a protein and a polyuridylated RNA (poly(U)RNA) is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "decreased polyU RNA binding" EXACT [PomBase:mah] synonym: "decreased polyuridylated RNA binding" EXACT [PomBase:mah] synonym: "decreased protein-poly(U) RNA interaction" EXACT [PomBase:mah] synonym: "reduced poly(U) RNA binding" EXACT [PomBase:mah] is_a: FYPO:0002134 ! decreased protein-RNA interaction created_by: midori creation_date: 2015-12-01T15:12:21Z [Term] id: FYPO:0005102 name: decreased protein level at silent mating-type cassette def: "A cell phenotype in which the amount of a protein found associated with chromatin at the mating type region is lower than normal when the cell is in the vegetative growth phase of the life cycle." [PMID:19117951, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level at mating type region" EXACT [PomBase:mah] synonym: "decreased protein level at mating type region chromatin" EXACT [PomBase:mah] synonym: "decreased protein level at mating type region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level at mating type region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level at mating type region heterochromatin" EXACT [PomBase:vw] synonym: "reduced protein level at mating type region" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2015-12-07T12:35:42Z [Term] id: FYPO:0005103 name: curved elongated vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is elongated, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] synonym: "curved elongated cell" EXACT [PomBase:mah] synonym: "curved elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "curved elongated vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000016 ! curved vegetative cell is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000016 ! curved vegetative cell relationship: has_part FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2015-12-07T12:37:38Z [Term] id: FYPO:0005104 name: abnormal Lys63-specific deubiquitinase activity def: "A molecular function phenotype in which the observed rate of Lys63-specific deubiquitinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-12-07T12:40:39Z [Term] id: FYPO:0005105 name: abolished Lys63-specific deubiquitinase activity def: "A molecular function phenotype in which Lys63-specific deubiquitinase activity is absent." [PomBase:mah] synonym: "Lys63-specific deubiquitinase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0005104 ! abnormal Lys63-specific deubiquitinase activity created_by: midori creation_date: 2015-12-07T12:40:46Z [Term] id: FYPO:0005106 name: decreased Lys63-specific deubiquitinase activity def: "A molecular function phenotype in which the observed rate of Lys63-specific deubiquitinase activity is decreased." [PomBase:mah] synonym: "reduced Lys63-specific deubiquitinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005104 ! abnormal Lys63-specific deubiquitinase activity created_by: midori creation_date: 2015-12-07T12:41:06Z [Term] id: FYPO:0005107 name: normal regulation of mitotic DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of mitotic DNA replication initiation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal regulation of DNA replication initiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GO:1903466] synonym: "normal regulation of mitotic DNA replication initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2015-12-07T13:12:39Z [Term] id: FYPO:0005108 name: normal rate of mitotic DNA replication elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is normal (i.e. indistinguishable from wild type)." [PMID:1902319, PomBase:mah] synonym: "normal rate of DNA replication elongation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal rate of DNA strand elongation involved in mitotic DNA replication" EXACT [PomBase:mah] synonym: "normal rate of DNA strand elongation involved in nuclear cell cycle DNA replication" EXACT [GO:1902319] synonym: "normal rate of mitotic DNA replication elongation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process during vegetative growth created_by: midori creation_date: 2015-12-07T13:18:20Z [Term] id: FYPO:0005109 name: premature protein localization to chromatin at replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins begins earlier than normal." [PMID:21518960, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to chromatin at replication origin" EXACT [PomBase:mah] synonym: "premature protein localisation to chromatin at replication origin" EXACT [PomBase:mah] synonym: "premature protein localization to chromatin at replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature protein localization to chromatin at replication origins during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-12-07T13:22:32Z [Term] id: FYPO:0005110 name: normal sodium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular sodium export" EXACT [PomBase:al] synonym: "normal sodium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal sodium export during vegetative growth" EXACT [PomBase:mah] synonym: "normal sodium export from cell" EXACT [PomBase:mah] synonym: "normal sodium ion export" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth created_by: midori creation_date: 2015-12-07T13:34:00Z [Term] id: FYPO:0005111 name: abnormal ubiquitin-specific protease activity def: "A molecular function phenotype in which the observed rate of ubiquitin-specific protease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2015-12-07T13:41:01Z [Term] id: FYPO:0005112 name: decreased ubiquitin-specific protease activity def: "A molecular function phenotype in which the observed rate of ubiquitin-specific protease activity is decreased." [PomBase:mah] synonym: "reduced ubiquitin-specific protease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005111 ! abnormal ubiquitin-specific protease activity created_by: midori creation_date: 2015-12-07T13:41:08Z [Term] id: FYPO:0005113 name: increased ubiquitin-specific protease activity def: "A molecular function phenotype in which the observed rate of ubiquitin-specific protease activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0005111 ! abnormal ubiquitin-specific protease activity created_by: midori creation_date: 2015-12-07T13:41:23Z [Term] id: FYPO:0005114 name: normal protein localization to endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endosome(s) is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to endosome" EXACT [PomBase:mah] synonym: "normal protein localization to endosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to endosome during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein targeting to endosome" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2015-12-07T13:52:49Z [Term] id: FYPO:0005115 name: elongated vegetative cell with central constriction def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells." [PomBase:mah, PomBase:vw] comment: Note that cell with this phenotype, often called dumbbell-shaped, are usually also elongated. The distinction between this phenotype and swollen elongated cells (FYPO:0001429) is that dumbbell-shaped cells have a constriction along the long axis, whereas swollen elongated cells do not. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cell morphology, elongated dumbbell" RELATED [PomBase:mah] synonym: "cell morphology, long dumbbell" RELATED [PomBase:vw] synonym: "elongated cell with central constriction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated cell with central constriction during vegetative growth" EXACT [PomBase:mah] synonym: "elongated dumbbell morphology" RELATED [PomBase:mah] synonym: "elongated dumbbell-shaped vegetative cell" RELATED [PomBase:vw] synonym: "elongated swollen vegetative cell with constricted region at cell division site" EXACT [PomBase:vw] is_a: FYPO:0001122 ! elongated vegetative cell created_by: midori creation_date: 2015-12-07T13:54:25Z [Term] id: FYPO:0005116 name: increased punctate nuclear protein localization def: "A cell phenotype in which a protein is localized to discrete regions in the nucleus, visible as foci or dots by microscopy, to a greater extent observed than in normal (wild type) cells." [PomBase:mah] comment: This term can be used for protein that do not normally localize to discrete nuclear regions, or for proteins that do normally show punctate localization but with such localization increased in a mutant. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localization to nuclear puncta" EXACT [PomBase:vw] synonym: "increased punctate nuclear protein localisation" EXACT [PomBase:mah] synonym: "increased punctate nuclear protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased punctate nuclear protein localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2015-12-08T16:21:53Z [Term] id: FYPO:0005117 name: normal transcription during nitrogen starvation def: "A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "normal transcription during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal transcription during nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal transcription during nitrogen limitation" EXACT [PomBase:mah] synonym: "normal transcription in response to nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0002882 ! normal transcription created_by: midori creation_date: 2015-12-08T16:23:13Z [Term] id: FYPO:0005118 name: decreased transcription during nitrogen starvation def: "A cellular process phenotype in which transcription occurs to a lower extent than normal when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). synonym: "decreased transcription during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased transcription during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased transcription during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased transcription during nitrogen limitation" EXACT [PomBase:mah] synonym: "decreased transcription in response to nitrogen starvation" EXACT [PomBase:mah, PomBase:vw] synonym: "decreased transcriptional response to nitrogen starvation" EXACT [PomBase:al] synonym: "reduced transcription during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002876 ! decreased transcription is_a: FYPO:0006550 ! decreased gene expression during nitrogen starvation created_by: midori creation_date: 2015-12-08T16:26:01Z [Term] id: FYPO:0005119 name: altered protein binding specificity def: "A molecular function phenotype in which a mutation causes a gene product to bind to one or more proteins with different specificity from normal. For example, a protein may bind to a protein in a mutant that it does not bind in wild type. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:25487150, PomBase:mah] comment: Also consider annotating to another term under 'abnormal protein binding', such as 'increased protein binding' (FYPO:0001571), to capture more details about the effect on protein binding specificity. synonym: "abnormal protein binding specificity" EXACT [PomBase:mah] synonym: "altered protein-protein interaction specificity" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2015-12-14T12:00:51Z [Term] id: FYPO:0005120 name: increased RNA level during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell is greater than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased RNA accumulation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcript level during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2015-12-14T12:10:13Z [Term] id: FYPO:0005121 name: decreased level of early meiotic gene mRNA during meiotic cell cycle def: "A cell phenotype in which the amount of RNA transcribed from early meiotic genes measured in a cell is lower than normal during the meiotic cell cycle. Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination." [PMID:17927811, PomBase:al, PomBase:mah] synonym: "decreased level of early meiosis gene mRNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of early meiotic gene RNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of early meiotic gene transcripts during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:11:26Z [Term] id: FYPO:0005122 name: decreased level of middle meiotic gene mRNA during meiotic cell cycle def: "A cell phenotype in which the amount of RNA transcribed from middle meiotic genes measured in a cell is lower than normal during the meiotic cell cycle. Middle meiotic genes are normally transcribed during meiotic nuclear division." [PMID:17927811, PomBase:al, PomBase:mah] synonym: "decreased level of middle meiosis gene mRNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of middle meiotic gene RNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of middle meiotic gene transcripts during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:14:25Z [Term] id: FYPO:0005123 name: decreased level of late meiotic gene mRNA during meiotic cell cycle def: "A cell phenotype in which the amount of RNA transcribed from late meiotic genes measured in a cell is lower than normal during the meiotic cell cycle. Late meiotic genes are normally transcribed during spore maturation." [PMID:17927811, PomBase:al, PomBase:mah] synonym: "decreased level of late meiosis gene mRNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of late meiotic gene RNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of late meiotic gene transcripts during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:15:41Z [Term] id: FYPO:0005124 name: increased level of early meiotic gene mRNA during late meiosis def: "A cell phenotype observed in late meiosis in which the amount of RNA transcribed from early meiotic genes measured in a cell is higher than normal. Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination." [PMID:17927811, PomBase:al, PomBase:mah] synonym: "increased level of early meiosis gene mRNA during late meiosis" EXACT [PomBase:mah] synonym: "increased level of early meiotic gene mRNA during late meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased level of early meiotic gene RNA during late meiosis" EXACT [PomBase:mah] synonym: "increased level of early meiotic gene transcripts during late meiosis" EXACT [PomBase:vw] synonym: "increased RNA level of early meiotic genes during late meiosis" EXACT [PomBase:al] is_a: FYPO:0005120 ! increased RNA level during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:18:13Z [Term] id: FYPO:0005125 name: increased level of nitrogen starvation gene mRNA during meiotic cell cycle def: "A cell phenotype in which the amount of one or more RNAs that are normally expressed during nitrogen starvation measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) during the meiotic cell cycle." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of cellular response to nitrogen starvation gene mRNA during meiotic cell cycle" EXACT [PomBase:al] synonym: "increased level of nitrogen depletion gene mRNA during meiotic cell cycle" EXACT [PomBase:vw] synonym: "increased level of nitrogen deprivation gene mRNA during meiotic cell cycle" EXACT [PomBase:vw] synonym: "increased level of nitrogen starvation gene RNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "increased level of nitrogen starvation gene transcripts during meiotic cell cycle" EXACT [PomBase:vw] synonym: "increased nitrogen starvation gene mRNA accumulation during meiotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005120 ! increased RNA level during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:19:43Z [Term] id: FYPO:0005126 name: increased level of carbohydrate metabolism gene mRNA during meiotic cell cycle def: "A cell phenotype in which the amount of one or more carbohydrate metabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) during the meiotic cell cycle. Carbohydrate metabolism RNAs are transcribed from genes whose products are involved in carbohydrate metabolic processes." [PMID:17927811, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased carbohydrate metabolism gene mRNA accumulation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of carbohydrate metabolic process mRNA during meiotic cell cycle" EXACT [PomBase:al] synonym: "increased level of carbohydrate metabolism gene RNA during meiotic cell cycle" EXACT [PomBase:mah] synonym: "increased level of carbohydrate metabolism gene transcripts during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0005120 ! increased RNA level during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:22:09Z [Term] id: FYPO:0005127 name: increased level of late meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from late meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Late meiotic genes are normally transcribed during spore maturation." [PMID:17927811, PomBase:al, PomBase:mah] synonym: "increased level of late meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of late meiotic gene mRNA during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of late meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of late meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0002173 ! increased level of meiotic gene mRNA during vegetative growth created_by: midori creation_date: 2015-12-14T12:26:42Z [Term] id: FYPO:0005128 name: increased level of middle meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from middle meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Middle meiotic genes are normally transcribed during meiotic nuclear division." [PMID:17927811, PomBase:al, PomBase:mah] synonym: "increased level of middle meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of middle meiotic gene mRNA during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of middle meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of middle meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0002173 ! increased level of meiotic gene mRNA during vegetative growth created_by: midori creation_date: 2015-12-14T12:28:29Z [Term] id: FYPO:0005129 name: increased level of heat shock gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during heat shock measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth)." [PMID:17927811, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased heat shock gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of cellular response to heat shock gene mRNA during vegetative growth" EXACT [PomBase:al] synonym: "increased level of heat shock gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of heat shock gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of heat shock gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-12-14T12:29:22Z [Term] id: FYPO:0005130 name: spores sensitive to heat def: "A cell phenotype in which spores germinate to a lower extent than wild type following exposure to heat." [PMID:24623719, PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2015-12-14T12:49:03Z [Term] id: FYPO:0005131 name: spores sensitive to ethanol def: "A cell phenotype in which spores germinate to a lower extent than wild type following exposure to ethanol." [PMID:24623719, PomBase:mah] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2015-12-14T12:49:30Z [Term] id: FYPO:0005132 name: spores sensitive to cell wall-degrading enzymes def: "A cell phenotype in which spores germinate to a lower extent than wild type following exposure to an enzymes that degrades cell wall polysaccharides." [PMID:24623719, PomBase:mah] synonym: "spores sensitive to glusulase" NARROW [PomBase:al] is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2015-12-14T12:50:00Z [Term] id: FYPO:0005133 name: decreased protein localization to ascospore wall def: "A cell phenotype in which the localization of a protein to the ascospore wall is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to ascospore wall" EXACT [PomBase:mah] synonym: "decreased protein localization to spore wall" EXACT [PomBase:mah] synonym: "reduced protein localization to ascospore wall" EXACT [PomBase:mah] is_a: FYPO:0004094 ! abnormal protein localization during meiotic cell cycle created_by: midori creation_date: 2015-12-14T12:54:07Z [Term] id: FYPO:0005134 name: decreased protein phosphorylation during cellular response to micafungin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to micafungin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to micafungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to micafungin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to micafungin" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2015-12-14T12:58:13Z [Term] id: FYPO:0005135 name: normal protein localization to linear element def: "A cell phenotype in which the localization of a protein to linear elements is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to linear element" EXACT [GO:0036181, PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis created_by: midori creation_date: 2015-12-14T13:00:01Z [Term] id: FYPO:0005136 name: normal meiotic DNA double-strand break formation def: "A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is normal (i.e. indistinguishable from wild type)." [GO:0042138, PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2015-12-14T13:16:11Z [Term] id: FYPO:0005137 name: delayed onset of meiotic DNA double-strand break formation def: "A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I begins later than normal." [GO:0042138, PomBase:mah] synonym: "delayed meiotic DNA double-strand break formation" EXACT [PomBase:mah] is_a: FYPO:0003564 ! abnormal meiotic DNA double-strand break formation created_by: midori creation_date: 2015-12-14T13:17:05Z [Term] id: FYPO:0005138 name: normal meiotic recombination double-strand break repair def: "A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is normal (i.e. indistinguishable from wild type)." [PMID:15238514, PomBase:mah] synonym: "normal double-strand break repair during meiotic recombination" EXACT [PomBase:mah] synonym: "normal double-strand break repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "normal DSB repair involved in reciprocal meiotic recombination" EXACT [PomBase:vw] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2015-12-14T13:18:54Z [Term] id: FYPO:0005139 name: abnormal meiotic recombination double-strand break repair def: "A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is abnormal." [PMID:15238514, PomBase:mah] synonym: "abnormal double-strand break repair during meiotic recombination" EXACT [PomBase:mah] synonym: "abnormal double-strand break repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "abnormal DSB repair involved in reciprocal meiotic recombination" EXACT [PomBase:vw] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2015-12-14T13:36:52Z [Term] id: FYPO:0005140 name: abolished meiotic recombination double-strand break repair def: "A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination does not occur." [PMID:15238514, PomBase:mah] synonym: "abolished double-strand break repair during meiotic recombination" EXACT [PomBase:mah] synonym: "abolished double-strand break repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "abolished DSB repair involved in reciprocal meiotic recombination" EXACT [PomBase:vw] synonym: "meiotic recombination double-strand break repair abolished" EXACT [PomBase:mah] is_a: FYPO:0005139 ! abnormal meiotic recombination double-strand break repair created_by: midori creation_date: 2015-12-14T13:39:04Z [Term] id: FYPO:0005141 name: decreased meiotic recombination double-strand break repair def: "A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is decreased." [PMID:15238514, PomBase:mah] synonym: "decreased double-strand break repair during meiotic recombination" EXACT [PomBase:mah] synonym: "decreased double-strand break repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "decreased DSB repair involved in reciprocal meiotic recombination" EXACT [PomBase:vw] synonym: "reduced meiotic recombination double-strand break repair" EXACT [PomBase:mah] is_a: FYPO:0005139 ! abnormal meiotic recombination double-strand break repair created_by: midori creation_date: 2015-12-14T13:39:15Z [Term] id: FYPO:0005142 name: decreased proteasome core complex binding def: "A molecular function phenotype in which occurrence of proteasome core complex binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:16096059, PomBase:mah] synonym: "reduced proteasome core complex binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2015-12-15T12:04:08Z [Term] id: FYPO:0005143 name: abolished proteasome core complex binding def: "A molecular function phenotype in which proteasome core complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:16096059, PomBase:mah] synonym: "proteasome core complex binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2015-12-15T12:04:20Z [Term] id: FYPO:0005144 name: decreased proteasome regulatory particle binding def: "A molecular function phenotype in which occurrence of proteasome regulatory particle binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:16096059, PomBase:mah] synonym: "reduced proteasome regulatory particle binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2015-12-15T12:06:06Z [Term] id: FYPO:0005145 name: abolished proteasome regulatory particle binding def: "A molecular function phenotype in which proteasome regulatory particle binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:16096059, PomBase:mah] synonym: "proteasome regulatory particle binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2015-12-15T12:06:10Z [Term] id: FYPO:0005146 name: normal proteasome localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a proteasome to the nuclear periphery is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal proteasome localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "normal proteasome localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal proteasome localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2015-12-15T12:11:38Z [Term] id: FYPO:0005147 name: abolished proteasome localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a proteasome to the nuclear periphery is abolished." [PomBase:mah] synonym: "abolished proteasome localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "abolished proteasome localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished proteasome localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] synonym: "proteasome localization to nuclear periphery abolished" EXACT [PomBase:mah] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth is_a: FYPO:0002338 ! abnormal protein localization to nuclear periphery created_by: midori creation_date: 2015-12-15T12:12:51Z [Term] id: FYPO:0005148 name: increased protein localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is increased. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane." [GO:0034399, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nuclear periphery" EXACT [PomBase:mah] synonym: "increased protein localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001130 ! increased protein localization to nucleus during vegetative growth is_a: FYPO:0002338 ! abnormal protein localization to nuclear periphery created_by: midori creation_date: 2015-12-15T12:13:31Z [Term] id: FYPO:0005149 name: septated spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid and has one or more septa." [PomBase:mah] synonym: "septated rounded vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0002342 ! septated vegetative cell relationship: has_part FYPO:0000021 ! spheroid vegetative cell relationship: has_part FYPO:0002342 ! septated vegetative cell created_by: midori creation_date: 2015-12-15T13:47:04Z [Term] id: FYPO:0005150 name: resistance to enfumafungin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of enfumafungin than normal." [PomBase:mah] synonym: "resistance to enfumafungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to enfumafungin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to enfumafungin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-12-15T13:48:52Z [Term] id: FYPO:0005151 name: resistance to pneumocandin B0 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of pneumocandin B0 than normal." [PomBase:mah] synonym: "resistance to pneumocandin B0 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to pneumocandin B0 during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to pneumocandin B0" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-12-15T13:55:58Z [Term] id: FYPO:0005152 name: resistance to caspofungin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caspofungin than normal." [PomBase:mah] synonym: "resistance to caspofungin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to caspofungin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to caspofungin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2015-12-15T13:56:45Z [Term] id: FYPO:0005153 name: increased number of heterothallic h- cells def: "A cell population phenotype in which a greater than normal number of cells in an originally homothallic (h90) population express M-specific information from the mat1 locus." [PomBase:al] synonym: "increased amount of heterothallic H- cells" EXACT [PomBase:al] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2015-12-15T14:09:44Z [Term] id: FYPO:0005154 name: decreased protein localization to heterochromatin at mat2P silent mating-type cassette def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the mat2P silent mating-type cassette is decreased." [PMID:18354497, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to heterochromatin at mat2P silent mating-type cassette" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at mat2P mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at mat2P silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at mat2P silent mating-type region" EXACT [PomBase:mah] synonym: "decreased protein localization to mat2P silent mating type cassette heterochromatin" EXACT [PomBase:al] synonym: "decreased protein localization to mat2P silent mating-type cassette heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to mat2P silent mating-type cassette heterochromatin during vegetative growth" EXACT [PomBase:al] synonym: "reduced protein localization to heterochromatin at mat2P silent mating-type cassette" EXACT [PomBase:mah] is_a: FYPO:0003573 ! decreased protein localization to heterochromatin at silent mating-type cassette created_by: midori creation_date: 2015-12-15T14:28:41Z [Term] id: FYPO:0005155 name: increased cellular ergosta-5,7,22,24(28)-tetraen-3beta-ol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosta-5,7,22,24(28)-tetraen-3beta-ol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular ergosta-5,7,22,24(28)-tetraen-3beta-ol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular ergosta-5,7,22,24(28)-tetraen-3beta-ol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased ergosta-5,7,22,24(28)-tetraen-3beta-ol accumulation" RELATED [PomBase:mah] is_a: FYPO:0002327 ! increased cellular sterol level created_by: midori creation_date: 2015-12-16T11:04:28Z [Term] id: FYPO:0005156 name: abnormal ascus morphology def: "A phenotype characterized by altered ascus morphology, i.e. the size, shape, or structure of the ascus is abnormal." [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2015-12-16T11:06:20Z [Term] id: FYPO:0005157 name: normal ascus morphology def: "A phenotype characterized by normal ascus morphology, i.e. the size, shape, and structure of the ascus are normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2015-12-16T11:07:15Z [Term] id: FYPO:0005158 name: decreased cell wall (1->6)-beta-D-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->6)-beta-D-glucan measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall (1->6)-beta-D-glucan accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall (1->6)-beta-D-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cell wall (1->6)-beta-D-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall (1->6)-beta-D-glucan level" EXACT [PomBase:mah] is_a: FYPO:0001082 ! decreased cell wall beta-glucan level is_a: FYPO:0002265 ! decreased cell wall galactomannan level created_by: midori creation_date: 2015-12-16T11:13:07Z [Term] id: FYPO:0005159 name: decreased DNA synthesis involved in mitotic DNA replication def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the synthesis of DNA that occurs as part of DNA replication is decreased." [PMID:22970243, PomBase:mah] synonym: "decreased DNA biosynthetic process involved in mitotic DNA replication" EXACT [GO:1904860] synonym: "decreased DNA synthesis involved in DNA replication during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased DNA synthesis involved in mitotic DNA replication during vegetative growth" EXACT [PomBase:mah] synonym: "reduced DNA synthesis involved in mitotic DNA replication" EXACT [PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2015-12-18T11:53:02Z [Term] id: FYPO:0005160 name: normal cell cycle progression following cellular response to hydroxyurea def: "A cellular process phenotype in which cell cycle progression is normal (i.e. indistinguishable from wild type) after exposure to hydroxyurea." [PMID:16849602, PomBase:mah] synonym: "normal cell cycle progression following cellular response to HU" EXACT [PomBase:mah] synonym: "normal cell cycle progression following HU exposure" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-12-18T12:00:13Z [Term] id: FYPO:0005161 name: delayed onset of cell cycle progression following cellular response to hydroxyurea def: "A cellular process phenotype in which cell cycle progression resumes after a longer time than normal after exposure to hydroxyurea." [PMID:16849602, PomBase:mah] synonym: "delayed cell cycle progression following cellular response to HU" EXACT [PomBase:mah] synonym: "delayed cell cycle progression following cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "delayed cell cycle progression following HU exposure" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2015-12-18T12:02:10Z [Term] id: FYPO:0005162 name: increased RNA level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to salt stress" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to salt stress" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0003198 ! altered RNA level during cellular response to osmotic stress created_by: midori creation_date: 2015-12-18T13:27:11Z [Term] id: FYPO:0005163 name: increased RNA level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to heat" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to high temperature" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to heat" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2015-12-18T13:28:13Z [Term] id: FYPO:0005164 name: increased haploidization during cellular response to UV def: "A cell phenotype in which non-sporulating diploid cells become haploid, without undergoing meiosis, at a higher frequency than normal during a cellular response to ultraviolet light." [PMID:7254221, PomBase:al, PomBase:mah] comment: Diploid cells may become haploid by chromosome loss, or by undergoing premature mitosis. Chromosome loss may also cause aneuploidy or cell death. synonym: "increased haploidisation during cellular response to UV" EXACT [PomBase:mah] synonym: "increased haploidization during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "unstable diploid during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001386 ! increased haploidization created_by: midori creation_date: 2015-12-18T13:41:07Z [Term] id: FYPO:0005165 name: abnormal spatio-temporal regulation of replication fork localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the spatio-temporal pattern of localization of replication forks into nuclear foci is abnormal. Normally, replication forks appear organized into foci outside the nucleolus in early S phase. As S phase progresses, the number of foci first increases, then decreases, and the remaining foci concentrate within the nucleolus or at the nucleolar periphery. The last replication foci remaining at the end of S phase are one or two large spots at the nucleolar border." [PMID:17304223, PomBase:mah] synonym: "abnormal replication foci dynamics" RELATED [PomBase:mah] synonym: "abnormal replication focus organization" RELATED [PomBase:mah] synonym: "abnormal spatio-temporal regulation of replication fork localisation" EXACT [PomBase:mah] synonym: "abnormal spatio-temporal regulation of replication fork localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spatio-temporal regulation of replication fork localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal spatio-temporal replication fork organization" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2015-12-18T14:14:47Z [Term] id: FYPO:0005166 name: normal spatio-temporal regulation of replication fork localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the spatio-temporal pattern of localization of replication forks into nuclear foci is normal (i.e. indistinguishable from wild type). Normally, replication forks appear organized into foci outside the nucleolus in early S phase. As S phase progresses, the number of foci first increases, then decreases, and the remaining foci concentrate within the nucleolus or at the nucleolar periphery. The last replication foci remaining at the end of S phase are one or two large spots at the nucleolar border." [PMID:17304223, PomBase:mah] synonym: "normal replication foci dynamics" RELATED [PomBase:mah] synonym: "normal replication focus organization" RELATED [PomBase:mah] synonym: "normal spatio-temporal regulation of replication fork localisation" EXACT [PomBase:mah] synonym: "normal spatio-temporal regulation of replication fork localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spatio-temporal regulation of replication fork localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal spatio-temporal replication fork organization" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2015-12-18T14:17:18Z [Term] id: FYPO:0005167 name: decreased protein localization to chromatin at centromere inner repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere inner repeat regions is decreased." [PMID:12925774, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at centromere inner repeat" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere imr" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2015-12-18T14:21:10Z [Term] id: FYPO:0005168 name: normal protein level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2015-12-18T14:27:34Z [Term] id: FYPO:0005169 name: increased histone H3-K9 methylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at the centromere central core occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation at centromere central core during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 methylation at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me at centromere central core during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at centromere central core during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0005066 ! increased histone H3-K9 methylation at centromere during vegetative growth created_by: midori creation_date: 2016-01-06T13:47:52Z [Term] id: FYPO:0005170 name: abnormal uracil import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell is abnormal." [PomBase:mah] synonym: "abnormal uracil import across plasma membrane" EXACT [GO:0098721] synonym: "abnormal uracil import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal uracil import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal uracil import into cell" EXACT [PomBase:al] synonym: "abnormal uracil uptake" EXACT [PomBase:mah] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2016-01-06T13:54:34Z [Term] id: FYPO:0005171 name: decreased uracil import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased uracil import across plasma membrane" EXACT [GO:0098721] synonym: "decreased uracil import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased uracil import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased uracil import into cell" EXACT [PomBase:al] synonym: "decreased uracil uptake" EXACT [PomBase:mah] synonym: "reduced uracil import" EXACT [PomBase:mah] is_a: FYPO:0005170 ! abnormal uracil import created_by: midori creation_date: 2016-01-06T13:54:46Z [Term] id: FYPO:0005172 name: increased uracil import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell occurs to a greater extent than normal." [PomBase:mah] synonym: "increased uracil import across plasma membrane" EXACT [GO:0098721] synonym: "increased uracil import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased uracil import during vegetative growth" EXACT [PomBase:mah] synonym: "increased uracil import into cell" EXACT [PomBase:al] synonym: "increased uracil uptake" EXACT [PomBase:mah] is_a: FYPO:0005170 ! abnormal uracil import created_by: midori creation_date: 2016-01-06T13:55:14Z [Term] id: FYPO:0005173 name: increased protein localization to cell surface def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is increased. The cell surface refers to the external part of the cell wall and/or plasma membrane." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell surface" EXACT [PomBase:mah] synonym: "increased protein localization to cell surface during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to cell surface during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002814 ! abnormal protein localization to cell surface created_by: midori creation_date: 2016-01-06T14:00:07Z [Term] id: FYPO:0005174 name: abolished uracil import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell does not occur." [PomBase:mah] synonym: "abolished uracil import across plasma membrane" EXACT [GO:0098721] synonym: "abolished uracil import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished uracil import during vegetative growth" EXACT [PomBase:mah] synonym: "abolished uracil import into cell" EXACT [PomBase:al] synonym: "abolished uracil uptake" EXACT [PomBase:mah] synonym: "uracil import abolished" EXACT [PomBase:mah] is_a: FYPO:0005170 ! abnormal uracil import created_by: midori creation_date: 2016-01-06T14:55:26Z [Term] id: FYPO:0005175 name: increased catalase activity def: "A molecular function phenotype in which the observed rate of catalase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001104 ! abnormal catalase activity created_by: midori creation_date: 2016-01-12T12:09:21Z [Term] id: FYPO:0005176 name: increased ferric-chelate reductase activity def: "A molecular function phenotype in which the observed rate of ferric-chelate reductase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001847 ! abnormal ferric-chelate reductase activity created_by: midori creation_date: 2016-01-12T12:10:22Z [Term] id: FYPO:0005177 name: abolished tRNA wobble position uridine thiolation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the modification of a wobble base uridine residue in a tRNA to 2-thiouridine is abolished." [GO:0003143, PomBase:mah] synonym: "abolished tRNA wobble position uridine thiolation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA wobble position uridine thiolation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished wobble position s2U biosynthesis" EXACT [GO:0002143, PomBase:mah] synonym: "tRNA wobble position uridine thiolation abolished" EXACT [PomBase:mah] is_a: FYPO:0008344 ! abolished tRNA modification created_by: midori creation_date: 2016-01-12T12:36:29Z [Term] id: FYPO:0005178 name: abnormal vacuolar morphology during nitrogen starvation def: "A physical cellular phenotype in which the size, shape, or structure of the fungal-type vacuole is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] comment: Note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuolar morphology during nitrogen depletion" EXACT [PomBase:mah] synonym: "abnormal vacuolar morphology during nitrogen deprivation" EXACT [PomBase:mah] synonym: "abnormal vacuole morphology during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002257 ! abnormal vacuolar morphology is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2016-01-12T12:46:53Z [Term] id: FYPO:0005179 name: abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) exposure during mitotic G1 phase is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to UV. The most common abnormality is for the cell cycle to progress as in the absence of UV." [PMID:15498101, PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to UV during mitotic G1 phase" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following UV exposure during mitotic G1 phase" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to ultraviolet light during mitotic G1 phase" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to UV during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0004254 ! abnormal mitotic cell cycle regulation during cellular response to UV created_by: midori creation_date: 2016-01-12T13:06:21Z [Term] id: FYPO:0005180 name: normal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) exposure during mitotic G1 phase is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to UV." [PMID:15498101, PomBase:mah] synonym: "normal cell cycle regulation during cellular response to UV during mitotic G1 phase" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle delay following UV exposure during mitotic G1 phase" EXACT [PomBase:al] synonym: "normal mitotic cell cycle regulation during cellular response to ultraviolet light during mitotic G1 phase" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation in response to UV during mitotic G1phase" EXACT [PomBase:mah] is_a: FYPO:0004014 ! normal mitotic cell cycle regulation during cellular response to UV created_by: midori creation_date: 2016-01-12T13:09:40Z [Term] id: FYPO:0005181 name: normal protein degradation during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein breakdown during cellular response to UV" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process during cellular response to UV" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism during cellular response to UV" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein degradation during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal protein degradation during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein degradation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002800 ! normal protein degradation during vegetative growth created_by: midori creation_date: 2016-01-12T13:27:52Z [Term] id: FYPO:0005182 name: decreased protein degradation during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased when the cell is exposed to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown during cellular response to UV" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during cellular response to UV" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during cellular response to UV" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during cellular response to ultraviolet light" EXACT [GO:0030163] synonym: "decreased protein degradation during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein degradation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein degradation during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0000846 ! decreased protein degradation during vegetative growth created_by: midori creation_date: 2016-01-12T13:30:35Z [Term] id: FYPO:0005183 name: abolished protein polyubiquitination during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the polyubiquitination of one or more specific proteins, or of specific protein sites, does not occur when the cell is exposed to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein polyubiquitination during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "abolished protein polyubiquitination during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein polyubiquitination during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein polyubiquitinylation during cellular response to UV" RELATED [GO:0000209, PomBase:mah] synonym: "abolished protein polyubiquitylation during cellular response to UV" EXACT [GO:0000209, PomBase:mah] synonym: "protein polyubiquitination abolished during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0005928 ! abolished protein polyubiquitination during vegetative growth created_by: midori creation_date: 2016-01-12T13:32:28Z [Term] id: FYPO:0005184 name: increased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 the C-terminal domain of RNA polymerase II occurs to a greater extent than normal." [GO:0071620, PomBase:mah] synonym: "increased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phosphorylation of RNA polymerase II CTD serine 5 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation created_by: midori creation_date: 2016-01-12T13:37:29Z [Term] id: FYPO:0005185 name: inviable after spore germination, multiple cell divisions, septated cell with condensed chromatin def: "A phenotype in which a spore germinates to produce a cell that contains one or more septa, has condensed chromatin, and undergoes two or more rounds of cell division, and then dies." [PMID:8557037, PomBase:al, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, septated cell with condensed chromatin" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, septated cell with condensed chromatin" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, septated cell with condensed chromatin" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2016-01-12T13:39:36Z [Term] id: FYPO:0005186 name: resistance to hexavalent chromium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hexavalent chromium ions (Cr6+) than normal." [PomBase:mah] synonym: "resistance to chromium(6+)" EXACT [CHEBI:33007] synonym: "resistance to chromium(VI) cation" EXACT [CHEBI:33007] synonym: "resistance to Cr(VI)" EXACT [PomBase:al] synonym: "resistance to Cr6+" EXACT [PomBase:mah] synonym: "resistance to hexavalent chromium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to hexavalent chromium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to hexavalent chromium ion" EXACT [PomBase:mah] synonym: "resistance to hexavalent chromium ions" EXACT [PomBase:mah] synonym: "resistant to hexavalent chromium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-01-12T13:53:59Z [Term] id: FYPO:0005187 name: decreased level of transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transport RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Transport RNAs are transcribed from genes whose products are involved in one or more transport processes." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of transport gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of transport gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2016-01-12T13:57:33Z [Term] id: FYPO:0005188 name: delayed onset of mitotic cell cycle arrest during cellular response to hydroxyurea def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to hydroxyurea exposure begins later than normal. Normally, cell cycle progression is slowed or arrested transiently following exposure to hydroxyurea." [PMID:19546237, PomBase:mah] synonym: "delayed cell cycle arrest during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "delayed cell cycle arrest in response to hydroxyurea" EXACT [PomBase:mah] synonym: "delayed onset of cell cycle arrest during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitotic cell cycle arrest during cellular response to HU" EXACT [PomBase:mah] is_a: FYPO:0000711 ! decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation is_a: FYPO:0001339 ! abnormal cellular response to starvation during vegetative growth is_a: FYPO:0001933 ! abnormal mitotic cell cycle regulation during cellular response to hydroxyurea created_by: midori creation_date: 2016-01-12T14:00:12Z [Term] id: FYPO:0005189 name: abnormal re-entry into mitotic cell cycle after arrest in response to hydroxyurea def: "A cellular process phenotype in which re-entry into the mitotic cell cycle is abnormal after arrest resulting from hydroxyurea exposure." [PMID:19546237, PomBase:mah] synonym: "abnormal re-entry into mitotic cell cycle after arrest in response to HU" EXACT [PomBase:mah] synonym: "abnormal re-entry into mitotic cell cycle after arrest in response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal re-entry into mitotic cell cycle after HU arrest" EXACT [PomBase:al] synonym: "abnormal re-entry into mitotic cell cycle after hydroxyurea-induced arrest" EXACT [PomBase:mah] is_a: FYPO:0001933 ! abnormal mitotic cell cycle regulation during cellular response to hydroxyurea created_by: midori creation_date: 2016-01-12T14:05:50Z [Term] id: FYPO:0005190 name: obsolete normal protein phosphorylation during cellular response to arginine def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to L-arginine." [PomBase:mah] comment: This term was made obsolete because it is overly specific, and not required for annotation. synonym: "normal protein phosphorylation during cellular response to arginine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to arginine during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to L-arginine" EXACT [GO:1903577] is_obsolete: true created_by: midori creation_date: 2016-01-15T11:41:31Z [Term] id: FYPO:0005191 name: normal cellular response to stress def: "A cellular response phenotype in which a cellular response to stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Use a descendant of this term if you have assayed the response to a stress at the subcellular or molecular level. subset: qc_do_not_manually_annotate is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2016-01-15T11:46:25Z [Term] id: FYPO:0005192 name: normal cellular response to nitrogen starvation def: "A stress response phenotype in which the response to nitrogen starvation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. Use this term if you have assayed the response to nitrogen starvation at the subcellular or molecular level. synonym: "normal cellular response to nitrogen depletion" EXACT [PomBase:vw] synonym: "normal cellular response to nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0005191 ! normal cellular response to stress created_by: midori creation_date: 2016-01-15T11:46:44Z [Term] id: FYPO:0005193 name: resistance to torin1 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of torin1 than normal." [PomBase:mah] synonym: "resistance to torin 1" EXACT [PomBase:mah] synonym: "resistance to torin1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to torin1 during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to torin1" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-01-15T11:50:08Z [Term] id: FYPO:0005194 name: decreased protein degradation during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during S phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown during mitotic S phase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during mitotic S phase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during mitotic S phase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein degradation during S phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein degradation during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0000846 ! decreased protein degradation during vegetative growth created_by: midori creation_date: 2016-01-15T11:55:37Z [Term] id: FYPO:0005195 name: normal protein degradation during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein breakdown during mitotic S phase" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process during mitotic S phase" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism during mitotic S phase" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein degradation during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein degradation during S phase during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002799 ! normal protein degradation created_by: midori creation_date: 2016-01-15T11:58:51Z [Term] id: FYPO:0005196 name: normal protein polyubiquitination during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the polyubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein polyubiquitination during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal protein polyubiquitination during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein polyubiquitination during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein polyubiquitinylation during cellular response to UV" RELATED [GO:0000209, PomBase:mah] synonym: "normal protein polyubiquitylation during cellular response to UV" EXACT [GO:0000209, PomBase:mah] is_a: FYPO:0002635 ! normal protein ubiquitination during vegetative growth created_by: midori creation_date: 2016-01-15T12:02:42Z [Term] id: FYPO:0005197 name: increased protein phosphorylation during glucose starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during glucose depletion" EXACT [PomBase:vw] synonym: "increased protein phosphorylation during glucose deprivation" EXACT [PomBase:vw] is_a: FYPO:0002680 ! increased protein phosphorylation created_by: midori creation_date: 2016-01-15T13:13:44Z [Term] id: FYPO:0005198 name: decreased protein kinase activity during cellular response to UV def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to ultraviolet light." [PomBase:mah] synonym: "decreased protein kinase activity during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "reduced protein kinase activity during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2016-01-15T13:45:05Z [Term] id: FYPO:0005199 name: decreased negative regulation of protein kinase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of a protein kinase activity occurs to a lower extent than normal." [PMID:14739927, PomBase:mah] synonym: "decreased inhibition of protein kinase activity" NARROW [PomBase:mah] synonym: "decreased negative regulation of protein kinase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased negative regulation of protein kinase activity during vegetative growth" EXACT [PomBase:mah] synonym: "reduced negative regulation of protein kinase activity" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2016-01-15T13:47:16Z [Term] id: FYPO:0005200 name: obsolete inviable elongated vegetative cell during cellular response to UV def: "OBSOLETE. A cell morphology phenotype in which a vegetative cell is inviable and elongated during a cellular response to ultraviolet light." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated inviable cell during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell during cellular response to UV" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell during cellular response to UV" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2016-01-15T13:48:20Z [Term] id: FYPO:0005201 name: abnormal mitotic cell cycle regulation during cellular response to heat stress def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to heat stress is abnormal." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to heat stress" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to heat stress during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to heat stress during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to heat stress" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-01-15T14:13:54Z [Term] id: FYPO:0005202 name: abnormal mitotic cell cycle regulation during cellular response to rapamycin def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to rapamycin is abnormal." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to rapamycin" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to rapamycin during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to rapamycin" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-01-15T14:21:39Z [Term] id: FYPO:0005203 name: sensitive to ethionine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethionine. Cells stop growing (and may die) at a concentration of ethionine that allows wild type cells to grow." [PomBase:mah] comment: Note that a racemic mixture of D and L enantiomers of ethionine is usually used to test sensitivity or resistance. synonym: "hypersensitive to ethionine" EXACT [PomBase:mah] synonym: "sensitive to DL-ethionine" RELATED [PomBase:mah] synonym: "sensitive to ethionine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to ethionine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to S-ethylhomocysteine" EXACT [CHEBI:68662] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-01-19T13:26:59Z [Term] id: FYPO:0005204 name: increased positive regulation of DNA-directed DNA polymerase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity occurs to a greater extent than normal." [PMID:9563836, PomBase:mah] synonym: "increased activation of DNA-directed DNA polymerase activity" NARROW [GO:1900264] synonym: "increased positive regulation of DNA polymerase activity" BROAD [PomBase:mah] synonym: "increased positive regulation of DNA-directed DNA polymerase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased positive regulation of DNA-directed DNA polymerase activity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2016-01-19T13:29:51Z [Term] id: FYPO:0005205 name: increased DNA polymerase processivity factor activity def: "A molecular function phenotype in which the rate or occurrence of DNA polymerase processivity factor activity is increased." [PomBase:mah] is_a: FYPO:0004499 ! abnormal DNA polymerase processivity factor activity created_by: midori creation_date: 2016-01-19T13:30:40Z [Term] id: FYPO:0005206 name: abnormal mitotic cell cycle regulation upon nitrogen source shift def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle when cells are shifted from one nitrogen source to another. Normally, cell division is delayed upon shifting from a poor to a rich nitrogen source, and accelerated upon shifting from a rich to a poor nitrogen source." [PMID:21965528, PMID:689088, PMID:872891, PomBase:mah] comment: Good (or rich) nitrogen sources are distinguished from poor sources based on how readily nitrogen is assimilated into cellular metabolism. In microorganisms, good nitrogen sources generally support higher cell population growth rates than poor sources. In fission yeast, cells divide at a smaller size when grown on a poor nitrogen source than in nitrogen-rich media; proline is commonly used as a poor nitrogen source. synonym: "abnormal cell cycle regulation upon nitrogen source shift" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation upon nitrogen source shift during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to nitrogen source shift" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation upon nitrogen source shift during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle created_by: midori creation_date: 2016-01-19T13:39:34Z [Term] id: FYPO:0005207 name: normal mitotic cell cycle regulation upon nitrogen source shift def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle is normal (i.e. indistinguishable from wild type) when cells are shifted from one nitrogen source to another. Normally, cell division is delayed upon shifting from a poor to a rich nitrogen source, and accelerated upon shifting from a rich to a poor nitrogen source." [PMID:21965528, PMID:689088, PMID:872891, PomBase:mah] comment: Good (or rich) nitrogen sources are distinguished from poor sources based on how readily nitrogen is assimilated into cellular metabolism. In microorganisms, good nitrogen sources generally support higher cell population growth rates than poor sources. In fission yeast, cells divide at a smaller size when grown on a poor nitrogen source than in nitrogen-rich media; proline is commonly used as a poor nitrogen source. synonym: "normal cell cycle regulation upon nitrogen source shift" EXACT [PomBase:mah] synonym: "normal cell cycle regulation upon nitrogen source shift during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to nitrogen source shift" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation upon nitrogen source shift during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2016-01-19T14:11:22Z [Term] id: FYPO:0005208 name: abolished protein localization during meiotic cell cycle def: "A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found during the meiotic cell cycle." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abolished protein localisation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "protein absent from specific location in cell during meiotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization abolished during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001375 ! abolished protein localization is_a: FYPO:0004094 ! abnormal protein localization during meiotic cell cycle is_a: FYPO:0006393 ! localization phenotype during meiotic cell cycle created_by: midori creation_date: 2016-01-20T13:20:46Z [Term] id: FYPO:0005209 name: abnormal protein localization to kinetochore def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the kinetochore and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to kinetochore" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2016-01-20T13:41:08Z [Term] id: FYPO:0005210 is_a: FYPO:0001269 ! abolished protein localization to kinetochore during vegetative growth [Term] id: FYPO:0005211 name: decreased protein localization to mitotic spindle pole body during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during anaphase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle pole body during anaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic SPB during anaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle pole body during mitotic anaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle pole body during anaphase" EXACT [PomBase:mah] is_a: FYPO:0002822 ! decreased protein localization to mitotic spindle pole body during mitosis created_by: midori creation_date: 2016-01-20T13:48:01Z [Term] id: FYPO:0005212 name: normal protein localization to kinetochore during mitotic prometaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during prometaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during mitotic prometaphase" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during prometaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0005779 ! normal protein localization to kinetochore during mitosis created_by: midori creation_date: 2016-01-20T13:49:14Z [Term] id: FYPO:0005213 name: normal regulation of translation in response to stress during vegetative growth def: "A gene expression phenotype in which regulation of translation in response to stress is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal regulation of translation in response to stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein synthesis after stress, normal during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0005044 ! translation regulation phenotype during vegetative growth is_a: FYPO:0005191 ! normal cellular response to stress created_by: midori creation_date: 2016-01-20T13:55:49Z [Term] id: FYPO:0005214 name: normal regulation of translation in response to osmotic stress def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to osmotic stress is normal (i.e. indistinguishable from wild type)." [PMID:26493332, PomBase:mah] synonym: "normal regulation of translation in response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal regulation of translation in response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005213 ! normal regulation of translation in response to stress during vegetative growth created_by: midori creation_date: 2016-01-20T13:57:55Z [Term] id: FYPO:0005215 name: decreased protein localization to kinetochore during mitotic M phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during mitotic M phase" [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein localization to kinetochore during mitotic nuclear division" EXACT [GO:0140014] synonym: "reduced protein localization to kinetochore during mitosis" EXACT [PomBase:mah] is_a: FYPO:0002902 ! decreased protein localization to kinetochore during vegetative growth is_a: FYPO:0008164 ! abnormal protein localization to kinetochore during mitotic M phase created_by: midori creation_date: 2016-01-20T14:09:52Z [Term] id: FYPO:0005216 name: normal protein localization to mitotic spindle pole body during metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during metaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle pole body during metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic SPB during metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle pole body during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole body during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole body during metaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0005709 ! normal protein localization to mitotic spindle pole body during mitosis created_by: midori creation_date: 2016-01-20T14:15:03Z [Term] id: FYPO:0005217 name: increased proteasome localization to nuclear periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a proteasome to the nuclear periphery is increased." [PomBase:mah] synonym: "increased proteasome localisation to nuclear periphery" RELATED [PomBase:mah] synonym: "increased proteasome localization to nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased proteasome localization to nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002338 ! abnormal protein localization to nuclear periphery created_by: midori creation_date: 2016-01-20T14:24:03Z [Term] id: FYPO:0005218 name: decreased level of histone H2A in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H2A measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased accumulation of histone H2A in cell" RELATED [PomBase:mah] synonym: "decreased cellular histone H2A level" EXACT [PomBase:mah] synonym: "decreased histone H2A level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of histone H2A in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of histone H2A in cell during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of histone H2A in cell" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2016-01-26T12:30:10Z [Term] id: FYPO:0005219 name: decreased transcript length def: "A phenotype in which a transcript, i.e. an RNA molecule synthesized on a DNA template by RNA polymerase, is shorter than normal." [PMID:26582768, PomBase:mah, SO:0000673] synonym: "short transcript" EXACT [PomBase:mah] synonym: "shortened transcript" EXACT [PomBase:mah] is_a: FYPO:0003048 ! abnormal transcript length created_by: midori creation_date: 2016-01-26T12:37:35Z [Term] id: FYPO:0005220 name: abnormal protein oligomerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oligomerization is abnormal." [GO:0051259, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein oligomerisation" EXACT [PomBase:mah] synonym: "abnormal protein oligomerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein oligomerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2016-01-26T12:46:18Z [Term] id: FYPO:0005221 name: normal protein oligomerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oligomerization is normal (i.e. indistinguishable from wild type)." [GO:0051259, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein oligomerisation" EXACT [PomBase:mah] synonym: "normal protein oligomerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein oligomerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2016-01-26T12:47:18Z [Term] id: FYPO:0005222 name: decreased histone H3 localization to chromatin at protein coding gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of histone H3 to chromatin at one or more protein-coding genes is decreased." [PMID:23028377, PomBase:mah] synonym: "decreased histone H3 localisation to chromatin at protein coding gene" EXACT [PomBase:mah] synonym: "decreased histone H3 localization to chromatin at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3 localization to chromatin at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3 localization to chromatin at protein coding gene" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-01-26T12:57:36Z [Term] id: FYPO:0005223 name: decreased histone H2B localization to chromatin at protein coding gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of histone H2B to chromatin at one or more protein-coding genes is decreased." [PMID:23028377, PomBase:mah] synonym: "decreased histone H2B localisation to chromatin at protein coding gene" EXACT [PomBase:mah] synonym: "decreased histone H2B localization to chromatin at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H2B localization to chromatin at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H2B localization to chromatin at protein coding gene" EXACT [PomBase:mah] is_a: FYPO:0008249 ! decreased protein localization to chromatin at protein coding gene created_by: midori creation_date: 2016-01-26T12:59:12Z [Term] id: FYPO:0005225 name: increased histone H3-K4 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 4 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K4 dimethylation during vegetative growth" EXACT [GO:0044648, PomBase:mah] synonym: "increased histone H3-K4 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K4 dimethylation during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K4me2 during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 dimethylation during vegetative growth" EXACT [GO:0044648, PomBase:mah] is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2016-01-26T13:13:38Z [Term] id: FYPO:0005226 name: decreased level of ubiquitinated protein in cell def: "A cell phenotype in which the amount of ubiquitinated protein measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased accumulation of ubiquitinated protein in cell" RELATED [PomBase:mah] synonym: "decreased level of ubiquitinated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of ubiquitinated protein in cell during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of ubiquitylated protein in cell" EXACT [PomBase:mah] synonym: "decreased ubiquitinated protein level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of ubiquitinated protein in cell" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2016-01-26T13:38:47Z [Term] id: FYPO:0005227 name: normal level of ubiquitinated protein in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal level of ubiquitinated protein during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of ubiquitinated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of ubiquitylated protein in cell" RELATED [PomBase:mah] synonym: "normal ubiquitinated protein accumulation" RELATED [PomBase:mah] synonym: "normal ubiquitinated protein level" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2016-01-26T13:40:17Z [Term] id: FYPO:0005228 name: normal growth on doxorubicin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing doxorubicin." [PomBase:mah] synonym: "normal cell population growth in presence of doxorubicin" EXACT [PomBase:mah] synonym: "normal cell population growth on doxorubicin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to doxorubicin" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on doxorubicin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2016-01-26T13:45:12Z [Term] id: FYPO:0005229 name: decreased transcription from RNA polymerase II promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from one or more RNA polymerase II promoters occurs to a lower extent than normal." [PMID:17339332, PomBase:mah] synonym: "decreased transcription from RNA pol II promoter during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription from RNA polymerase II promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced transcription from RNA polymerase II promoter" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2016-02-02T12:06:39Z [Term] id: FYPO:0005230 name: normal regulation of translation in response to UV def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to ultraviolet light is normal (i.e. indistinguishable from wild type)." [PMID:26493332, PomBase:mah] synonym: "normal regulation of translation in response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal regulation of translation in response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal regulation of translation in response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0005044 ! translation regulation phenotype during vegetative growth created_by: midori creation_date: 2016-02-02T12:16:20Z [Term] id: FYPO:0005231 name: loss of viability in stationary phase upon glucose starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase, when cells the population are subject to glucose starvation." [PMID:26624998, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased viability in stationary phase upon glucose starvation" EXACT [PomBase:mah] synonym: "growth defect, required for stationary phase upon glucose starvation" RELATED [PomBase:mah] synonym: "loss of cell population viability in stationary phase upon glucose starvation" EXACT [PomBase:mah] synonym: "loss of viability in stationary phase during glucose starvation" EXACT [PomBase:mah] synonym: "reduced viability in stationary phase upon glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000245 ! loss of viability in stationary phase is_a: FYPO:0004162 ! loss of viability upon glucose starvation created_by: midori creation_date: 2016-02-02T12:20:17Z [Term] id: FYPO:0005232 name: normal protein complex binding def: "A molecular function phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a protein complex that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000703 ! normal protein-protein interaction created_by: midori creation_date: 2016-02-02T12:33:02Z [Term] id: FYPO:0005233 name: normal MCM complex binding def: "A molecular function phenotype in which the binding of one protein to an MCM complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the MCM complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." [PMID:12604790, PomBase:mah] comment: This term can be used for any interaction with a protein complex that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0005232 ! normal protein complex binding created_by: midori creation_date: 2016-02-02T12:35:09Z [Term] id: FYPO:0005234 name: abolished MCM complex binding def: "A molecular function phenotype in which MCM complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:12604790, PomBase:mah] synonym: "MCM complex binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2016-02-02T12:36:45Z [Term] id: FYPO:0005235 name: abolished protein localization to chromatin at stalled replication fork def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is abolished." [PMID:21945095, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at stalled replication fork during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at stalled replication fork during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to chromatin at stalled replication fork during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-02-02T12:46:39Z [Term] id: FYPO:0005236 name: normal protein localization to chromatin at stalled replication fork def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is normal (i.e. indistinguishable from wild type)." [PMID:21945095, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at stalled replication fork" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at stalled replication fork during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at stalled replication fork during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-02-02T12:48:26Z [Term] id: FYPO:0005237 name: increased cellular proline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-proline level" EXACT [CHEBI:17203, PomBase:al] synonym: "increased cellular proline level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular proline level during vegetative growth" EXACT [PomBase:mah] synonym: "increased proline accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-02T13:38:36Z [Term] id: FYPO:0005238 name: increased cellular tryptophan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tryptophan measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-tryptophan level" EXACT [CHEBI:16828, PomBase:al] synonym: "increased cellular tryptophan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular tryptophan level during vegetative growth" EXACT [PomBase:mah] synonym: "increased tryptophan accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-02T13:40:18Z [Term] id: FYPO:0005239 name: increased cellular tyrosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-tyrosine level" EXACT [CHEBI:17895, PomBase:al] synonym: "increased cellular tyrosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular tyrosine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased tyrosine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-02T13:42:12Z [Term] id: FYPO:0005240 name: decreased cellular tryptophan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tryptophan measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-tryptophan level" EXACT [PomBase:mah] synonym: "decreased cellular tryptophan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular tryptophan level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of tryptophan in cell" EXACT [PomBase:mah] synonym: "reduced cellular tryptophan level" EXACT [PomBase:mah] synonym: "reduced level of tryptophan in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-02T13:43:08Z [Term] id: FYPO:0005241 name: decreased cellular tyrosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-tyrosine level" EXACT [PomBase:mah] synonym: "decreased cellular tyrosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular tyrosine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of tyrosine in cell" EXACT [PomBase:mah] synonym: "reduced cellular tyrosine level" EXACT [PomBase:mah] synonym: "reduced level of tyrosine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-02T13:44:08Z [Term] id: FYPO:0005242 name: decreased cell population growth on glutamine nitrogen source def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing glutamine as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on glutamine nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on glutamine nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth with glutamine nitrogen source" NARROW [PomBase:mah] synonym: "reduced cell growth on glutamine nitrogen source" EXACT [PomBase:mah] synonym: "slow cell growth on glutamine nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2016-02-02T13:47:09Z [Term] id: FYPO:0005243 name: increased cell population growth on glutamine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing glutamine as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on glutamine nitrogen source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on glutamine nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-02T13:48:06Z [Term] id: FYPO:0005244 name: decreased cell population growth on arabinose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing arabinose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on arabinose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on arabinose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on arabinose carbon source" RELATED [PomBase:mah] synonym: "slow cell growth on arabinose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2016-02-02T13:49:31Z [Term] id: FYPO:0005245 name: increased cell population growth on arabinose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing arabinose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on arabinose carbon source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on arabinose carbon source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-02T13:50:01Z [Term] id: FYPO:0005246 name: decreased cell population growth on melibiose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing melibiose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on melibiose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on melibiose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on melibiose carbon source" RELATED [PomBase:mah] synonym: "slow cell growth on melibiose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2016-02-02T13:50:52Z [Term] id: FYPO:0005247 name: increased cell population growth on melibiose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing melibiose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on melibiose carbon source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on melibiose carbon source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-02T13:51:38Z [Term] id: FYPO:0005248 name: resistance to tellurite def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tellurite (TeO3(2-)) ions than normal." [PomBase:mah] synonym: "resistance to tellurite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tellurite during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to tellurite ions" EXACT [PomBase:mah] synonym: "resistant to tellurite" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-02-02T13:55:18Z [Term] id: FYPO:0005249 name: resistance to caesium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caesium ions than normal." [PomBase:mah] synonym: "resistance to caesium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to caesium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to caesium ions" EXACT [PomBase:mah] synonym: "resistance to cesium" EXACT [PomBase:mah] synonym: "resistant to caesium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-02-02T13:57:17Z [Term] id: FYPO:0005250 name: sensitive to caesium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caesium ions. Cells stop growing (and may die) at a concentration of caesium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to caesium" EXACT [PomBase:mah] synonym: "sensitive to caesium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to caesium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to caesium ions" EXACT [PomBase:mah] synonym: "sensitive to cesium" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-02-02T13:58:25Z [Term] id: FYPO:0005251 name: sensitive to tellurite def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tellurite (TeO3(2-)) ions. Cells stop growing (and may die) at a concentration of tellurite ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tellurite" EXACT [PomBase:mah] synonym: "sensitive to tellurite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tellurite during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to tellurite ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-02-02T13:59:16Z [Term] id: FYPO:0005252 name: sensitive to tamoxifen def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tamoxifen. Cells stop growing (and may die) at a concentration of tamoxifen that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tamoxifen" EXACT [PomBase:mah] synonym: "sensitive to tamoxifen during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tamoxifen during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-02-02T14:04:41Z [Term] id: FYPO:0005253 name: resistance to tamoxifen def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tamoxifen than normal." [PomBase:mah] synonym: "resistance to tamoxifen during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tamoxifen during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tamoxifen" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-02-02T14:05:15Z [Term] id: FYPO:0005254 name: normal growth on tamoxifen def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tamoxifen." [PomBase:mah] synonym: "normal cell population growth in presence of tamoxifen" EXACT [PomBase:mah] synonym: "normal cell population growth on tamoxifen" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to tamoxifen" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tamoxifen" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2016-02-02T14:06:18Z [Term] id: FYPO:0005255 name: abnormal carboxypeptidase activity def: "A molecular function phenotype in which the observed rate of a carboxypeptidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-02-08T13:06:37Z [Term] id: FYPO:0005256 name: decreased carboxypeptidase activity def: "A molecular function phenotype in which the observed rate of a carboxypeptidase activity is decreased." [PomBase:mah] synonym: "reduced carboxypeptidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005255 ! abnormal carboxypeptidase activity created_by: midori creation_date: 2016-02-08T13:06:43Z [Term] id: FYPO:0005257 name: decreased cellular proline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-proline level" EXACT [PomBase:mah] synonym: "decreased cellular proline level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular proline level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of proline in cell" EXACT [PomBase:mah] synonym: "reduced cellular proline level" EXACT [PomBase:mah] synonym: "reduced level of proline in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-08T13:24:15Z [Term] id: FYPO:0005258 name: increased cell population growth at high temperature def: "A cell population phenotype in which the growth of a population of cells is increased relative to normal in the vegetative growth phase of the life cycle at high temperatures." [PomBase:mah] comment: For fission yeast, high temperature usually corresponds to above 32 degrees Celsius. Use this term if you have assayed growth of cells exposed to heat in culture. If you have assayed the response to heat at the subcellular or molecular level, consider annotating to 'abnormal cellular response to heat' (FYPO:0000212). synonym: "heat resistance" RELATED [PomBase:mah] synonym: "increased cell population growth at high temperature during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased growth at high temperature" BROAD [PomBase:mah] synonym: "increased vegetative cell population growth at high temperature" EXACT [PomBase:mah] synonym: "resistance to heat" RELATED [PomBase:mah] synonym: "resistance to high temperature" RELATED [PomBase:mah] synonym: "resistance to high temperature during vegetative growth" RELATED [PomBase:mah] synonym: "resistant to heat" RELATED [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-08T13:29:57Z [Term] id: FYPO:0005259 name: increased cell density in stationary phase def: "A cell population phenotype in which a population reaches stationary phase at, and maintains, a higher cell density than wild type." [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2016-02-08T13:32:46Z [Term] id: FYPO:0005260 name: increased cell population growth at low temperature def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal at a low temperature." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. For fission yeast, low temperature usually corresponds to below 25 degrees Celsius. synonym: "cold resistance" RELATED [PomBase:mah] synonym: "cold resistant" RELATED [PomBase:mah] synonym: "increased growth at low temperature" BROAD [PomBase:mah] synonym: "increased vegetative cell population growth at low temperature" EXACT [PomBase:mah] synonym: "resistance to cold" RELATED [PomBase:mah] synonym: "resistance to cold during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to cold during vegetative growth" RELATED [PomBase:mah] synonym: "resistant to cold during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-08T13:36:00Z [Term] id: FYPO:0005261 name: increased cell population growth on galactose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing galactose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on galactose carbon source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on galactose carbon source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-08T13:38:11Z [Term] id: FYPO:0005262 name: increased cell population growth on maltose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing maltose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on maltose carbon source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on maltose carbon source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2016-02-08T13:38:28Z [Term] id: FYPO:0005263 name: increased cellular arginine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased arginine accumulation" RELATED [PomBase:mah] synonym: "increased cellular arginine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular arginine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-arginine level" EXACT [CHEBI:16467, PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-02-08T13:51:51Z [Term] id: FYPO:0005264 name: resistance to dithiothreitol def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of dithiothreitol than normal." [PomBase:mah] synonym: "resistance to 1,4-dithiothreitol" EXACT [CHEBI:18320] synonym: "resistance to dithiothreitol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to dithiothreitol during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to dithiothreitol" EXACT [PomBase:mah] synonym: "resistant to DTT" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-02-08T13:52:58Z [Term] id: FYPO:0005265 name: resistance to lead def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lead ions than normal." [PomBase:mah] synonym: "resistance to lead during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to lead during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to lead ions" EXACT [PomBase:mah] synonym: "resistant to lead" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-02-08T13:54:56Z [Term] id: FYPO:0005266 name: resistance to sodium dodecyl sulfate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium dodecyl sulfate (SDS) than normal." [PomBase:mah] synonym: "resistance to sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to sodium dodecyl sulphate" EXACT [PomBase:mah] synonym: "resistant to SDS" EXACT [PomBase:mah] synonym: "resistant to sodium dodecyl sulfate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-02-08T13:55:56Z [Term] id: FYPO:0005267 name: sensitive to aluminium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to aluminium ions. Cells stop growing (and may die) at a concentration of aluminium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to aluminium" EXACT [PomBase:mah] synonym: "sensitive to aluminium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to aluminium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to aluminium ions" EXACT [PomBase:mah] synonym: "sensitive to aluminum" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-02-08T13:58:25Z [Term] id: FYPO:0005268 name: abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to methyl methanesulfonate (MMS) is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to MMS. The most common abnormality is for the cell cycle to progress as in the absence of MMS." [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle delay following methyl methanesulfonate exposure" EXACT [PomBase:al] synonym: "abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to MMS" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-02-08T14:02:47Z [Term] id: FYPO:0005269 name: decreased protein kinase activity during cellular response to hydrogen peroxide def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to hydrogen peroxide." [PomBase:mah] synonym: "decreased protein kinase activity during cellular response to H2O2" EXACT [PomBase:mah] synonym: "reduced protein kinase activity during cellular response to H2O2" EXACT [PomBase:mah] synonym: "reduced protein kinase activity during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2016-02-08T14:52:23Z [Term] id: FYPO:0005270 name: decreased protein kinase activity during cellular response to osmotic stress def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to osmotic stress." [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2016-02-08T14:53:13Z [Term] id: FYPO:0005271 name: abnormal microtubule plus-end directed mitotic chromosome migration def: "A cellular process phenotype in which microtubule plus-end directed mitotic chromosome migration is abnormal. In microtubule plus-end directed mitotic chromosome migration, chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules." [GO:0099606, PomBase:mah] synonym: "abnormal microtubule plus-end directed chromosome migration during mitosis" EXACT [PomBase:mah] synonym: "abnormal microtubule plus-end directed chromosome migration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal microtubule plus-end directed mitotic chromosome migration during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal plus-end directed chromosome gliding" EXACT [GO:0099606] is_a: FYPO:0002737 ! abnormal mitotic cell cycle process is_a: FYPO:0006329 ! abnormal organelle localization relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2016-02-16T11:22:07Z [Term] id: FYPO:0005272 name: abolished microtubule plus-end directed mitotic chromosome migration def: "A cellular process phenotype in which microtubule plus-end directed mitotic chromosome migration does not occur. In microtubule plus-end directed mitotic chromosome migration, chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules." [GO:0099606, PomBase:mah] synonym: "abolished microtubule plus-end directed chromosome migration during mitosis" EXACT [PomBase:mah] synonym: "abolished microtubule plus-end directed mitotic chromosome migration during vegetative growth" EXACT [PomBase:mah] synonym: "abolished microtubule plus-end-directed mitotic chromosome migration" EXACT [PomBase:mah] synonym: "abolished plus-end directed chromosome gliding" EXACT [GO:0099606] synonym: "microtubule plus-end directed mitotic chromosome migration abolished" EXACT [PomBase:mah] is_a: FYPO:0005271 ! abnormal microtubule plus-end directed mitotic chromosome migration created_by: midori creation_date: 2016-02-16T11:22:22Z [Term] id: FYPO:0005273 name: abnormal cell cycle phase transition def: "A cellular process phenotype in which a cell does not execute a cell cycle phase transition normally." [GO:0044770, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0002734 ! abnormal cell cycle process created_by: midori creation_date: 2016-02-16T11:34:52Z [Term] id: FYPO:0005274 name: abnormal meiotic cell cycle phase transition def: "A cellular process phenotype in which a cell does not execute a meiotic cell cycle phase transition normally." [GO:0044771, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0005273 ! abnormal cell cycle phase transition created_by: midori creation_date: 2016-02-16T11:36:17Z [Term] id: FYPO:0005275 name: abnormal mitotic cell cycle phase transition def: "A cellular process phenotype in which a cell does not execute a mitotic cell cycle phase transition normally." [GO:0044772, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0005273 ! abnormal cell cycle phase transition created_by: midori creation_date: 2016-02-16T11:37:08Z [Term] id: FYPO:0005277 name: multinucleate multiseptate cell def: "A cell morphology phenotype in which a cell has two or more nuclei and more than one septum per cell." [PomBase:mah] is_a: FYPO:0003341 ! multinucleate is_a: FYPO:0004295 ! multiseptate cell created_by: midori creation_date: 2016-02-16T14:09:56Z [Term] id: FYPO:0005278 name: decreased level of glucose-repressed gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more glucose-repressed mRNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Glucose-repressed mRNAs are transcribed from genes whose transcription is negatively regulated when glucose is present." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased glucose-repressed gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of glucose-repressed gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of glucose-repressed gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of glucose-repressed gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of glucose-repressed gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2016-02-16T14:13:27Z [Term] id: FYPO:0005279 name: increased level of glucose-repressed gene mRNA during vegetative growth alt_id: FYPO:0005287 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more glucose-repressed mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Glucose-repressed mRNAs are transcribed from genes whose transcription is negatively regulated when glucose is present." [PMID:18430926, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased glucose starvation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased glucose-repressed gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of cellular response to glucose starvation gene mRNA during vegetative growth" EXACT [PomBase:al] synonym: "increased level of glucose depletion gene mRNA during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of glucose deprivation gene mRNA during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of glucose starvation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of glucose starvation gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of glucose starvation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of glucose starvation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of glucose-repressed gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of glucose-repressed gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of glucose-repressed gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2016-02-16T14:16:15Z [Term] id: FYPO:0005280 name: normal level of glucose-repressed gene mRNA during vegetative growth alt_id: FYPO:0005076 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more glucose-repressed mRNAs measured in a cell is normal (i.e. indistinguishable from wild type). Glucose-repressed mRNAs are transcribed from genes whose transcription is negatively regulated when glucose is present." [PMID:17261596, PomBase:mah] synonym: "normal glucose starvation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "normal glucose-repressed gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "normal level of glucose starvation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of glucose starvation gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of glucose starvation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of glucose starvation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "normal level of glucose-repressed gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of glucose-repressed gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of glucose-repressed gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2016-02-16T14:17:18Z [Term] id: FYPO:0005281 name: obsolete inviable elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation def: "OBSOLETE. A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains DNA broken into small fragments when the cell is exposed to ionizing radiation." [PMID:1594599, PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated inviable cell with fragmented DNA during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "inviable elongated cell with fragmented DNA during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented DNA during cellular response to gamma radiation" NARROW [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation" EXACT [PomBase:mah, PomBase:vw] synonym: "inviable elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus during cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell with fragmented DNA during cellular response to ionizing radiation" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2016-02-16T14:48:16Z [Term] id: FYPO:0005282 name: sensitive to inositol starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to inositol starvation." [PMID:19606215, PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to inositol starvation in culture. synonym: "decreased growth during cellular response to inositol starvation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to inositol starvation" EXACT [PomBase:mah] synonym: "hypersensitive to inositol starvation" EXACT [PomBase:mah] synonym: "reduced growth in low inositol" RELATED [PomBase:vw] synonym: "sensitive to inositol depletion" EXACT [PomBase:vw] synonym: "sensitive to inositol deprivation" EXACT [PomBase:vw] synonym: "sensitive to inositol starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to inositol starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2016-02-16T15:00:39Z [Term] id: FYPO:0005283 name: increased viability upon inositol starvation def: "A cell population phenotype in which a larger than normal proportion of cells in the population remains viable when cells the population are subject to inositol starvation." [PMID:19606215, PomBase:mah] synonym: "increased cell population viability upon inositol starvation" EXACT [PomBase:mah] synonym: "increased viability during inositol starvation" EXACT [PomBase:mah] synonym: "increased viability upon inositol depletion" EXACT [PomBase:al] synonym: "increased viability upon inositol deprivation" EXACT [PomBase:mah] synonym: "increased viability upon inositol limitation" EXACT [PomBase:mah] is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2016-02-16T15:02:15Z [Term] id: FYPO:0005284 name: obsolete cut during cellular response to bleomycin def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to bleomycin. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic chromosome segregation during cellular response to bleomycin" EXACT [PomBase:vw] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2016-02-18T15:22:26Z [Term] id: FYPO:0005285 name: decreased cysteine-type endopeptidase activity def: "A molecular function phenotype in which the observed rate of a cysteine-type endopeptidase activity is decreased." [PomBase:mah] synonym: "decreased caspase activity" NARROW [PomBase:mah] synonym: "reduced cysteine-type endopeptidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004128 ! abnormal cysteine-type peptidase activity created_by: midori creation_date: 2016-02-16T15:06:44Z [Term] id: FYPO:0005286 name: heterochromatin assembly beyond boundary element IRC1L def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the centromere than normal, such that it extends beyond the IRC1L boundary element." [PMID:25972440, PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRC1L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRC1L during vegetative growth" EXACT [PomBase:mah] synonym: "heterochromatin formation beyond boundary element IRC1L" EXACT [PomBase:mah] is_a: FYPO:0004948 ! increased spatial extent of centromeric heterochromatin assembly created_by: midori creation_date: 2016-02-16T15:18:44Z [Term] id: FYPO:0005288 name: decreased negative regulation of transcription by glucose def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) occurs to a lower extent than normal. Specific genes that are normally not transcribed in the presence of glucose are transcribed in the mutant." [GO:0045014, PMID:18430926, PomBase:mah] synonym: "decreased glucose repression" EXACT [GO:0045014, PomBase:mah] synonym: "decreased glucose repression during vegetative growth" EXACT [PomBase:mah] synonym: "decreased negative regulation of transcription by glucose during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased negative regulation of transcription by glucose during vegetative growth" EXACT [PomBase:mah] synonym: "glucose repression defects" RELATED [PomBase:mah] synonym: "glucose-insensitive transcription" RELATED [PomBase:vw] synonym: "increased transcription of glucose starvation gene during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000044 ! abnormal negative regulation of transcription by glucose created_by: midori creation_date: 2016-02-16T15:24:04Z [Term] id: FYPO:0005289 name: actomyosin contractile ring sliding def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of the mitotic actomyosin contractile ring in the correct location is abnormal." [GO:0032189, PMID:26132084, PomBase:mah] synonym: "abnormal cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [PomBase:vw] synonym: "abnormal maintenance of mitotic actomyosin contractile ring localization" EXACT [PomBase:vw] synonym: "actomyosin contractile ring sliding during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actomyosin contractile ring sliding during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth relationship: has_output FYPO:0002026 ! actomyosin contractile ring displaced from midpoint created_by: midori creation_date: 2016-02-16T15:34:03Z [Term] id: FYPO:0005290 name: decreased protein localization to plasma membrane at cell division site during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is decreased." [PMID:26132084, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to plasma membrane at cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to plasma membrane at cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to plasma membrane at cell division site during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005544 ! abnormal protein localization to plasma membrane at cell division site during vegetative growth created_by: midori creation_date: 2016-02-16T15:40:54Z [Term] id: FYPO:0005291 name: increased RNA level during cellular response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to zinc ion" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to zinc ion" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to excess zinc ions" NARROW [PMID:24831008] synonym: "increased RNA level during cellular response to zinc" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during cellular response to zinc ion" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2016-02-16T15:57:02Z [Term] id: FYPO:0005292 name: increased chromatin binding during cellular response to hydroxyurea def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to hydroxyurea. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "increased chromatin binding during cellular response to HU" EXACT [PomBase:mah] is_a: FYPO:0002980 ! increased chromatin binding created_by: midori creation_date: 2016-02-16T16:28:00Z [Term] id: FYPO:0005293 name: decreased protein-protein interaction during cellular response to methyl methanesulfonate def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to methyl methanesulfonate. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction during cellular response to MMS" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction in response to methyl methanesulfonate" RELATED [PomBase:al] synonym: "reduced protein-protein interaction during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction created_by: midori creation_date: 2016-02-16T16:29:44Z [Term] id: FYPO:0005294 name: decreased protein-protein interaction during cellular response to hydroxyurea def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hydroxyurea. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein-protein interaction in response to hydroxyurea" RELATED [PomBase:al] synonym: "reduced protein-protein interaction during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction created_by: midori creation_date: 2016-02-16T16:30:30Z [Term] id: FYPO:0005295 name: decreased RNA catabolic process during nitrogen starvation def: "A cellular process phenotype which the occurrence of an RNA catabolic process is decreased when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased RNA breakdown during nitrogen starvation" EXACT [GO:0006401] synonym: "decreased RNA catabolic process during nitrogen deprivation" EXACT [PomBase:mah] synonym: "decreased RNA catabolism during nitrogen depletion" EXACT [GO:0006401] synonym: "decreased RNA degradation during nitrogen starvation" EXACT [GO:0006401] synonym: "reduced RNA catabolic process during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0003552 ! decreased RNA catabolic process created_by: midori creation_date: 2016-02-24T14:48:09Z [Term] id: FYPO:0005296 name: increased number of Rad52 foci during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during S phase of the mitotic cell cycle." [PMID:18045993, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during mitotic S phase" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during S phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2016-02-24T14:51:17Z [Term] id: FYPO:0005297 name: normal 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2016-02-26T14:25:40Z [Term] id: FYPO:0005298 name: normal oxidized DNA binding def: "A molecular function phenotype in which occurrence of oxidized DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2016-02-26T14:31:39Z [Term] id: FYPO:0005299 name: normal mitotic G2 DNA damage checkpoint during cellular response to UV def: "A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage." [PomBase:mah] synonym: "normal G2 DNA damage checkpoint during cellular response to UV during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint activation during cellular response to UV" EXACT [PomBase:al] synonym: "normal mitotic G2 DNA damage checkpoint during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002102 ! normal mitotic DNA damage checkpoint during cellular response to UV is_a: FYPO:0006578 ! normal mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2016-02-26T17:11:08Z [Term] id: FYPO:0005300 name: decreased protein localization to kinetochore during mitotic spindle assembly checkpoint signaling def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during mitotic spindle assembly checkpoint signaling." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to kinetochore during mitotic spindle assembly checkpoint signalling" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during mitotic cell cycle spindle assembly checkpoint signaling" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during signal transduction involved in mitotic spindle assembly checkpoint" EXACT [GO:0072480] synonym: "decreased protein localization to kinetochore during spindle assembly checkpoint signaling during mitotic cell cycle" EXACT [PomBase:mah] synonym: "defective protein recruitment to unattached kinetochores" EXACT [PomBase:vw] synonym: "reduced protein localization to kinetochore during mitotic spindle assembly checkpoint signaling" EXACT [PomBase:mah] is_a: FYPO:0005215 ! decreased protein localization to kinetochore during mitotic M phase created_by: midori creation_date: 2016-03-02T11:54:24Z [Term] id: FYPO:0005301 name: increased level of cell cycle regulated gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell cycle-regulated mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Cell cycle-regulated mRNAs are transcribed from genes whose level of transcription varies depending on cell cycle phase." [PMID:26697368, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased cell cycle regulated gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of cell cycle regulated gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of cell cycle regulated gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of cell cycle regulated gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of cell cycle-regulated gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2016-03-02T11:57:01Z [Term] id: FYPO:0005302 name: decreased RNA level during mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during the G2 phase of the mitotic cell cycle is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during mitotic G2 phase" RELATED [PomBase:mah] synonym: "decreased RNA level during G2 phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased RNA level during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during mitotic G2 phase" EXACT [PomBase:vw] synonym: "reduced RNA level during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2016-03-02T13:30:40Z [Term] id: FYPO:0005303 name: obsolete elongated vegetative cell during cellular response to UV def: "OBSOLETE. A cell morphology phenotype in which a vegetative cell is elongated during a cellular response to ultraviolet light." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the morphology term with conditions specified. synonym: "elongated cell during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "elongated vegetative cell during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "elongated vegetative cell during cellular response to UV" EXACT [PomBase:mah] synonym: "elongated vegetative cell during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2016-03-02T13:46:09Z [Term] id: FYPO:0005304 name: increased duration of mitotic interphase def: "A cellular process phenotype in which the duration of progression through interphase of the mitotic cell cycle is longer than normal." [PomBase:mah] comment: Use this term if it is not possible to tell which of G1, S or G2 phase has increased duration. synonym: "decreased rate of mitotic interphase progression" RELATED [PomBase:mah] synonym: "delayed mitotic interphase progression" RELATED [PomBase:mah] synonym: "delayed mitotic interphase progression during vegetative growth" RELATED [PomBase:mah] synonym: "increased duration of interphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged mitotic interphase" EXACT [PomBase:mah] synonym: "reduced rate of mitotic interphase progression" RELATED [PomBase:mah] is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-03-02T13:47:38Z [Term] id: FYPO:0005305 name: normal duration of mitotic interphase def: "A cell cycle phenotype in which the duration of interphase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2016-03-02T13:50:06Z [Term] id: FYPO:0005306 name: abnormal protein localization to centromeric chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with centromeric chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to centromeric chromatin during vegetative growth" EXACT [GO:0071168, PomBase:mah] synonym: "abnormal protein localization to centromeric chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to chromatin at centromere" EXACT [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-03-02T13:55:19Z [Term] id: FYPO:0005307 name: decreased phospholipid binding def: "A molecular function phenotype in which occurrence of phospholipid binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds one or more phospholipids less than wild type, or that a mutation in one gene decreases phospholipid binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "reduced phospholipid binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2016-03-02T14:02:25Z [Term] id: FYPO:0005308 name: increased histone H4-K8 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K8 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K8 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth created_by: midori creation_date: 2016-03-02T14:14:54Z [Term] id: FYPO:0005309 name: increased histone H4-K5 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K5 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K5 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth created_by: midori creation_date: 2016-03-02T14:15:57Z [Term] id: FYPO:0005310 name: increased histone H3-K14 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth is_a: FYPO:0000788 ! abnormal histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2016-03-02T14:16:35Z [Term] id: FYPO:0005311 name: normal histone H3-K4 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "normal histone H3-K4 methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K4me during vegetative growth" EXACT [GO:0051568, PomBase:mah] synonym: "normal histone lysine H3 K4 methylation during vegetative growth" EXACT [GO:0051568, PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2016-03-02T14:17:38Z [Term] id: FYPO:0005312 name: normal establishment of mitotic sister chromatid cohesion def: "A cellular process phenotype in which establishment of mitotic sister chromatid cohesion is normal (i.e. indistinguishable from wild type). Establishment of mitotic sister chromatid cohesion is the process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase of the mitotic cell cycle." [GO:0034087, PomBase:mah] synonym: "normal establishment of mitotic chromosome cohesion" EXACT [PomBase:mah] synonym: "normal establishment of mitotic sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "normal establishment of sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-03-02T14:23:54Z [Term] id: FYPO:0005313 name: normal maintenance of mitotic sister chromatid cohesion def: "A cellular process phenotype in which maintenance of mitotic sister chromatid cohesion is normal (i.e. indistinguishable from wild type). Maintenance of mitotic sister chromatid cohesion is the process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the mitotic spindle, and congress to the metaphase plate." [GO:0034088, PomBase:mah] synonym: "normal maintenance of mitotic chromosome cohesion" EXACT [PomBase:mah] synonym: "normal maintenance of mitotic sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "normal maintenance of sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-03-02T14:26:47Z [Term] id: FYPO:0005314 name: decreased protein localization to chromatin at MCB promoters during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is decreased." [PMID:26912660, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at MCB promoters during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB promoters during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB target genes during vegetative growth" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at MCB-containing promoters during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at MCB promoters during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-03-02T16:09:00Z [Term] id: FYPO:0005315 name: increased chromatin silencing at centromere central core def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of negative regulation of transcription at the central core of the centromeric regions is increased." [PomBase:mah] synonym: "increased chromatin silencing at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased negative regulation of transcription at centromere central core" RELATED [GO:0045892] synonym: "increased transcriptional repression at centromere central core" RELATED [PomBase:mah] is_a: FYPO:0000640 ! abnormal chromatin silencing at centromere central core created_by: midori creation_date: 2016-03-07T14:12:13Z [Term] id: FYPO:0005316 name: increased histone H4-K12 acetylation at subtelomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in subtelomeric regions occurs to a greater extent than normal." [PMID:22771823, PomBase:mah] synonym: "increased histone H4-K12 acetylation at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K12 acetylation at subtelomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H4K12 acetylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased subtelomeric histone H4K12 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0007631 ! increased histone H4-K12 acetylation during vegetative growth created_by: midori creation_date: 2016-03-07T14:15:11Z [Term] id: FYPO:0005317 name: obsolete increased histone H4-K8 and H4-K16 acetylation at subtelomere during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 8 and 16 of histone H4 in subtelomeric regions occurs to a greater extent than normal." [PMID:23851719, PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "increased histone H4 acetylation (K8 and K16) at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K8 and H4-K16 acetylation at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K8 and H4-K16 acetylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K8/16 acetylation at subtelomere during vegetative growth" EXACT [PMID:22771823, PomBase:al] is_obsolete: true consider: FYPO:0006752 consider: FYPO:0007315 created_by: midori creation_date: 2016-03-07T14:29:17Z [Term] id: FYPO:0005318 name: decreased transcription from MCB promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more MluI cell cycle box factor elements (MCBs) occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased transcription from MCB promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from MCB promoter during vegetative growth" EXACT [PomBase:mah] synonym: "expression of MBF target genes decreased" RELATED [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2016-03-07T15:04:46Z [Term] id: FYPO:0005319 name: inviable after spore germination, multiple cell divisions, spherical cell with cell lysis def: "A phenotype in which a spore germinates to produce a cell that is spherical, and undergoes two or more rounds of cell division before all cells die, and some cells lyse." [PMID:9636183, PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, spherical cell with cell lysis" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, spherical cell with cell lysis" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, spherical cell with cell lysis" EXACT [PomBase:mah] is_a: FYPO:0002148 ! inviable after spore germination, multiple cell divisions, abnormal morphology created_by: midori creation_date: 2016-03-07T15:25:27Z [Term] id: FYPO:0005320 name: normal protein level during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during metaphase of mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during mitotic metaphase" RELATED [PomBase:mah] synonym: "normal protein level during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein level during mitotic metaphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2016-03-15T14:59:03Z [Term] id: FYPO:0005321 name: inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic metaphase def: "A cell morphology phenotype in which a vegetative cell is inviable contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested in mitotic metaphase." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest in metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest in mitotic metaphase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell arrested in metaphase" EXACT [PomBase:jh] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in metaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic metaphase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest in metaphase" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic metaphase arrest" EXACT [PomBase:vw] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic nuclear division arrest in metaphase" EXACT [PomBase:vw] synonym: "lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic metaphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in metaphase with elongated inviable mononucleate aseptate cell" EXACT [PomBase:vw] synonym: "mitotic metaphase arrested elongated inviable mononucleate aseptate vegetative cell" EXACT [PomBase:mah] synonym: "nuclear division arrest in metaphase without septation (elongated cell)" EXACT [PomBase:vw] is_a: FYPO:0000620 ! abnormal cell cycle arrest in mitotic metaphase is_a: FYPO:0003128 ! inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase relationship: has_part FYPO:0000620 ! abnormal cell cycle arrest in mitotic metaphase created_by: midori creation_date: 2016-03-15T15:11:26Z [Term] id: FYPO:0005322 name: normal anaphase-promoting complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which anaphase-promoting complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal anaphase-promoting complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal anaphase-promoting complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal APC assembly" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2016-03-15T15:21:06Z [Term] id: FYPO:0005323 name: abnormal error-free translesion synthesis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which error-free translesion synthesis is abnormal. Error-free translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across from the lesion." [GO:0070987, PomBase:mah] synonym: "abnormal error-free translesion synthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal error-free translesion synthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-03-15T15:22:41Z [Term] id: FYPO:0005324 name: decreased error-free translesion synthesis of cyclobutane pyrimidine dimers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of cyclobutane pyrimidine dimers by error-free translesion synthesis occurs to a lower extent than normal." [PMID:20453833, PomBase:mah] synonym: "decreased error-free translesion synthesis across TT-CPD" EXACT [PMID:20453833] synonym: "decreased error-free translesion synthesis of cyclobutane pyrimidine dimers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased error-free translesion synthesis of cyclobutane pyrimidine dimers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005323 ! abnormal error-free translesion synthesis created_by: midori creation_date: 2016-03-15T15:26:57Z [Term] id: FYPO:0005325 name: normal error-free translesion synthesis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which error-free translesion synthesis is normal (i.e. indistinguishable from wild type). Error-free translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across from the lesion." [GO:0070987, PomBase:mah] synonym: "normal error-free translesion synthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal error-free translesion synthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-03-15T15:31:54Z [Term] id: FYPO:0005326 name: normal error-prone translesion synthesis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which error-prone translesion synthesis is normal (i.e. indistinguishable from wild type). Error-prone translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication." [GO:0042276, PomBase:mah] synonym: "normal error-prone translesion synthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal error-prone translesion synthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-03-15T15:32:14Z [Term] id: FYPO:0005327 name: abolished error-free translesion synthesis of cyclobutane pyrimidine dimers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of cyclobutane pyrimidine dimers by error-free translesion synthesis does not occur." [PMID:20453833, PomBase:mah] synonym: "abolished error-free translesion synthesis across TT-CPD" EXACT [PMID:20453833] synonym: "abolished error-free translesion synthesis of cyclobutane pyrimidine dimers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished error-free translesion synthesis of cyclobutane pyrimidine dimers during vegetative growth" EXACT [PomBase:mah] synonym: "error-free translesion synthesis of cyclobutane pyrimidine dimers abolished" RELATED [PomBase:mah] is_a: FYPO:0005323 ! abnormal error-free translesion synthesis created_by: midori creation_date: 2016-03-15T15:34:46Z [Term] id: FYPO:0005328 name: normal error-free translesion synthesis of cyclobutane pyrimidine dimers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of cyclobutane pyrimidine dimers by error-free translesion synthesis is normal (i.e. indistinguishable from wild type)." [PMID:20453833, PomBase:mah] synonym: "normal error-free translesion synthesis across TT-CPD" EXACT [PMID:20453833] synonym: "normal error-free translesion synthesis of cyclobutane pyrimidine dimers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal error-free translesion synthesis of cyclobutane pyrimidine dimers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005325 ! normal error-free translesion synthesis created_by: midori creation_date: 2016-03-15T15:36:04Z [Term] id: FYPO:0005329 name: normal error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-free translesion synthesis is normal (i.e. indistinguishable from wild type)." [PMID:20453833, PomBase:mah] synonym: "normal error-free translesion synthesis across TT(6-4)" EXACT [PMID:20453833] synonym: "normal error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005325 ! normal error-free translesion synthesis created_by: midori creation_date: 2016-03-15T15:37:21Z [Term] id: FYPO:0005330 name: decreased error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-free translesion synthesis occurs to a lower extent than normal." [PMID:20453833, PomBase:mah] synonym: "decreased error-free translesion synthesis across TT-(6-4)" EXACT [PMID:20453833] synonym: "decreased error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005323 ! abnormal error-free translesion synthesis created_by: midori creation_date: 2016-03-15T15:41:48Z [Term] id: FYPO:0005331 name: decreased error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-prone translesion synthesis occurs to a lower extent than normal." [PMID:20453833, PomBase:mah] synonym: "decreased error-prone translesion synthesis across TT-(6-4)" EXACT [PMID:20453833] synonym: "decreased error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003892 ! abnormal error-prone translesion synthesis created_by: midori creation_date: 2016-03-15T15:42:27Z [Term] id: FYPO:0005332 name: abolished error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-prone translesion synthesis does not occur." [PMID:20453833, PomBase:mah] synonym: "abolished error-prone translesion synthesis across TT-(6-4)" EXACT [PMID:20453833] synonym: "abolished error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts during vegetative growth" EXACT [PomBase:mah] synonym: "error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts abolished" EXACT [PomBase:mah] is_a: FYPO:0003892 ! abnormal error-prone translesion synthesis created_by: midori creation_date: 2016-03-15T15:44:01Z [Term] id: FYPO:0005333 name: increased protein level during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to methyl methanesulfonate is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2016-03-15T15:47:20Z [Term] id: FYPO:0005334 name: increased number of Holliday junctions def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the Holliday junctions is greater than normal. A Holliday junction is a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices." [GO:0000400, PMID:15367656, PomBase:mah] comment: This phenotype can be detected by measuring the amount of DNA that migrates as X-shaped in two-dimensional agarose gels. synonym: "increased amount of X-shaped DNA" RELATED [PomBase:pr] synonym: "increased number of four-way junctions" EXACT [PMID:22927644] synonym: "increased number of Holliday junctions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Holliday junctions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2016-03-15T15:49:17Z [Term] id: FYPO:0005335 name: abnormal cell cycle arrest at mitotic G2/M phase transition during glucose starvation def: "A cellular process phenotype in which progression through mitotic cell cycle arrest at the mitotic G2/M phase transition occurs abnormally when the cell is subject to glucose starvation." [PMID:26804466, PomBase:al, PomBase:mah] comment: Cells normally arrest the mitotic cell cycle at the mitotic G2/M phase transition when subject to glucose starvation. Use this term if the G2 arrest does not occur exactly as in wild type cells. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during glucose deprivation" EXACT [PomBase:vw] synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during glucose limitation" RELATED [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic G2 phase during glucose depletion" EXACT [PomBase:vw] synonym: "abnormal mitotic cell cycle arrest at mitotic G2/M phase transition during glucose starvation" EXACT [PomBase:mah] synonym: "abolished mitotic G2/M phase transition during glucose starvation" RELATED [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle progression created_by: midori creation_date: 2016-04-04T12:44:23Z [Term] id: FYPO:0005336 name: normal level of histone H3 in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal accumulation of histone H3 in cell" RELATED [PomBase:mah] synonym: "normal cellular histone H3 level" EXACT [PomBase:mah] synonym: "normal histone H3 level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of histone H3 in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of histone H3 in cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004981 ! normal cellular histone level created_by: midori creation_date: 2016-04-04T12:58:29Z [Term] id: FYPO:0005337 name: obsolete increased histone H3-K9K14 acetylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 9 and 14 of histone H3 occurs to a greater extent than normal." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to separate terms referring each modified position. synonym: "increased histone H3 K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 and K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9K14 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone lysine H3 K9K14 acetylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0000892 consider: FYPO:0005310 created_by: midori creation_date: 2016-04-04T13:00:33Z [Term] id: FYPO:0005338 name: decreased protein localization to nucleus during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to hydroxyurea" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2016-04-04T13:13:07Z [Term] id: FYPO:0005339 name: increased protein localization to nucleus during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus during cellular response to hydroxyurea" EXACT [GO:0034504, PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to HU" EXACT [PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001130 ! increased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2016-04-04T13:14:31Z [Term] id: FYPO:0005340 name: normal histone H4 deacetylation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deacetylation of lysine at position 4 of histone H4 is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea." [PMID:24478943, PomBase:mah] synonym: "normal histone H4 deacetylation during cellular response to HU" EXACT [PomBase:mah] synonym: "normal histone H4 deacetylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H4 deacetylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002600 ! normal histone modification during vegetative growth created_by: midori creation_date: 2016-04-04T13:31:16Z [Term] id: FYPO:0005341 name: decreased chromatin binding during cellular response to hydroxyurea def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased during a cellular response to hydroxyurea. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "decreased chromatin binding during cellular response to HU" EXACT [PomBase:mah] synonym: "reduced chromatin binding during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2016-04-04T13:41:04Z [Term] id: FYPO:0005342 name: normal rate of mitotic spindle elongation during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is normal (i.e. indistinguishable from wild type) during anaphase B." [PMID:19686686, PomBase:mah] synonym: "normal mitotic spindle elongation rate during anaphase B" EXACT [PomBase:mah] synonym: "normal rate of mitotic spindle elongation during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of spindle elongation during anaphase B of mitosis" EXACT [PomBase:mah] synonym: "normal rate of spindle elongation during mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0004429 ! normal rate of mitotic spindle elongation created_by: midori creation_date: 2016-04-04T13:45:04Z [Term] id: FYPO:0005343 name: decreased rate of mitotic spindle elongation during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased during anaphase B." [PMID:19686686, PomBase:mah] synonym: "decreased rate of mitotic spindle elongation during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of mitotic spindle elongation during mitotic anaphase B" EXACT [PomBase:mah] synonym: "decreased rate of mitotic spindle extension during anaphase B" EXACT [PomBase:vw] synonym: "decreased rate of spindle elongation during anaphase B of mitosis" EXACT [PomBase:mah] synonym: "reduced rate of mitotic spindle elongation during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0003268 ! decreased rate of mitotic spindle elongation created_by: midori creation_date: 2016-04-04T13:47:23Z [Term] id: FYPO:0005344 name: abolished mitotic spindle midzone assembly def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap, does not occur." [GO:0051256, PomBase:mah] synonym: "abolished mitotic spindle midzone assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished spindle midzone assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished spindle midzone assembly involved in mitosis" EXACT [GO:0051256] synonym: "mitotic spindle midzone assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0003304 ! abnormal mitotic spindle midzone assembly created_by: midori creation_date: 2016-04-04T14:07:20Z [Term] id: FYPO:0005345 name: mitotic sister chromatid separation during interphase def: "A cellular process phenotype in which mitotic sister chromatid separation begins during interphase of the cell cycle." [PMID:9808627, PomBase:mah] synonym: "advanced mitotic sister chromatid separation during interphase" EXACT [PomBase:mah] synonym: "chromosome separation during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic chromosome separation during interphase" EXACT [GO:0051306] synonym: "premature mitotic sister chromatid separation during interphase" EXACT [PomBase:mah] synonym: "premature sister chromatid separation during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "sister chromatid separation during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0000416 ! premature mitotic sister chromatid separation is_a: FYPO:0007125 ! mitotic sister chromatid separation in absence of mitotic spindle created_by: midori creation_date: 2016-04-04T14:27:35Z [Term] id: FYPO:0005346 name: abolished protein localization to cytoplasm, with protein mislocalized to nucleus during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is abolished, and the protein is instead present in the nucleus, during interphase of the mitotic cell cycle." [PMID:9635190, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cytoplasm, with protein mislocalised to nucleus during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasm, with protein mislocalized to nucleus during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to cytoplasm, with protein mislocalized to nucleus during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cytoplasm abolished, with protein mislocalized to nucleus during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2016-04-11T12:39:57Z [Term] id: FYPO:0005347 name: pointed nucleus during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus has a pointed shape during interphase of the mitotic cell cycle." [PMID:12390246, PomBase:mah] comment: Nuclear chromatin within the nucleus also assumes a pointed shape, and the point is associated with the spindle pole body. synonym: "pointed nucleus during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "pointed nucleus during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth created_by: midori creation_date: 2016-04-11T13:35:04Z [Term] id: FYPO:0005348 name: abnormal spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body (SPB)-led chromosome movement is abnormal. SPB-led chromosome movement is a microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase." [PomBase:mah] {comment="GO:0140404"} synonym: "abnormal maintenance of mitotic spindle pole body localization" RELATED [PomBase:mah] synonym: "abnormal maintenance of SPB localization" RELATED [PomBase:mah] synonym: "abnormal mitotic SPB oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal SPB-led chromosome movement during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal spindle pole body-led chromosome movement during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased spindle pole body-led chromosome movement during interphase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000534 ! abnormal mitotic spindle pole body localization created_by: midori creation_date: 2016-04-11T13:08:55Z [Term] id: FYPO:0005349 name: increased spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body (SPB) moves rapidly back and forth to a greater extent and over a larger area than normal, causing increased chromosome movement. Normally, SPB oscillation occurs during mitotic interphase (as well as prophase) but is restricted to a small space." [PMID:12390246, PMID:19001497, PomBase:mah] synonym: "increased mitotic SPB oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "increased mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "increased mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "increased SPB-led chromosome movement during mitotic interphase" EXACT [PomBase:mah] synonym: "increased spindle pole body-led chromosome movement during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005348 ! abnormal spindle pole body-led chromosome movement during mitotic interphase created_by: midori creation_date: 2016-04-11T13:12:53Z [Term] id: FYPO:0005350 name: abnormal chromatin organization resulting in peripheral chromatin distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such that chromatin is distributed in a ring-shaped structure around the nuclear periphery rather than throughout the nucleus." [PMID:16453724, PomBase:mah] synonym: "abnormal chromatin organisation resulting in peripheral chromatin distribution" EXACT [PomBase:mah] synonym: "abnormal chromatin organization resulting in peripheral chromatin distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromatin organization resulting in peripheral chromatin distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin organization resulting in ring-shaped chromatin distribution" EXACT [PomBase:vw] synonym: "abnormal nuclear chromatin organization resulting in peripheral chromatin distribution" EXACT [PomBase:mah] synonym: "chromatin abnormally dispersed around nuclear periphery" RELATED [PomBase:vw] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2015-03-16T13:58:17Z [Term] id: FYPO:0005351 name: increased guanyl-nucleotide exchange factor activity def: "A molecular function phenotype in which the observed rate or other property of a guanyl-nucleotide exchange factor activity is abnormal." [PomBase:mah] comment: This term can mean that the mutated gene product itself has greater GEF activity than wild type, or that a mutation in one gene increases GEF activation by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "increased GEF activity" EXACT [GO:0005085] is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2016-04-11T13:56:31Z [Term] id: FYPO:0005352 name: normal attachment of mitotic spindle microtubules to kinetochore def: "A cellular process phenotype in which the physical attachment of sister chromatids to mitotic spindle microtubules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to kinetochore mitosis" EXACT [PomBase:mah] synonym: "normal attachment of mitotic spindle microtubules to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "normal attachment of spindle microtubules to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0003570 ! normal attachment of spindle microtubules to kinetochore created_by: midori creation_date: 2016-04-11T14:01:33Z [Term] id: FYPO:0005353 name: normal replication fork arrest at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the RTS1 barrier is normal (i.e. indistinguishable from wild type). Note that the RTS1 barrier usually occurs in the mating type locus, but might be assayed at ectopic loci to maximise the distance that a restarted fork travels." [] {comment="PomBase:vw"} synonym: "normal replication fork arrest at mating-type locus" RELATED [] synonym: "normal replication fork arrest at mating-type locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal replication fork arrest at mating-type locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008191 ! normal replication fork arrest created_by: midori creation_date: 2016-04-11T14:59:17Z [Term] id: FYPO:0005354 name: normal site-specific DNA replication termination at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at the RTS1 barrier in the mating type region is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal site-specific DNA replication termination at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal site-specific DNA replication termination at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-04-11T15:03:01Z [Term] id: FYPO:0005355 name: abnormal site-specific DNA replication termination at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region is abnormal." [PomBase:mah] synonym: "abnormal site-specific DNA replication termination at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal site-specific DNA replication termination at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2016-04-11T15:13:14Z [Term] id: FYPO:0005356 name: abolished site-specific DNA replication termination at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region does not occur." [PomBase:mah] synonym: "abolished site-specific DNA replication termination at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished site-specific DNA replication termination at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] synonym: "site-specific DNA replication termination at RTS1 barrier abolished" EXACT [PomBase:mah] is_a: FYPO:0005355 ! abnormal site-specific DNA replication termination at RTS1 barrier created_by: midori creation_date: 2016-04-11T15:13:27Z [Term] id: FYPO:0005357 name: decreased site-specific DNA replication termination at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased site-specific DNA replication termination at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased site-specific DNA replication termination at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] synonym: "reduced site-specific DNA replication termination at RTS1 barrier" EXACT [PomBase:mah] is_a: FYPO:0005355 ! abnormal site-specific DNA replication termination at RTS1 barrier created_by: midori creation_date: 2016-04-11T15:13:32Z [Term] id: FYPO:0005358 name: increased site-specific DNA replication termination at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region occurs to a greater extent than normal." [PomBase:mah] synonym: "increased site-specific DNA replication termination at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased site-specific DNA replication termination at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005355 ! abnormal site-specific DNA replication termination at RTS1 barrier created_by: midori creation_date: 2016-04-11T15:13:38Z [Term] id: FYPO:0005359 name: normal termination of RNA polymerase II transcription at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at the RTS1 replication fork barrier is normal (i.e. indistinguishable from wild type)." [PMID:12840005, PomBase:mah] synonym: "normal RNA polymerase II release at RTS1 barrier" RELATED [PomBase:mah] synonym: "normal RNA polymerase II transcription termination at RTS1 barrier" EXACT [GO:0006369] synonym: "normal termination of RNA polymerase II transcription at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal termination of RNA polymerase II transcription at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006279 ! normal termination of RNA polymerase II transcription created_by: midori creation_date: 2016-04-11T15:21:56Z [Term] id: FYPO:0005360 name: reversed RTS1 barrier polarity def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the RTS1 replication termination site prevents replication fork movement in the opposite of normal direction. Normally, RTS1 acts as a barrier to replication forks moving in the cenII-distal direction." [PMID:18723894, PomBase:mah] synonym: "reversed RTS1 barrier polarity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reversed RTS1 barrier polarity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003083 ! abnormal replication fork arrest at mating-type locus created_by: midori creation_date: 2016-04-11T15:40:34Z [Term] id: FYPO:0005361 name: increased level of large-Y replication intermediates def: "A cell phenotype in which the level of large Y-shaped DNA replication intermediates is greater than normal. Large Y-shaped intermediates are formed late in the passive replication of a DNA region by a replication fork moving from outside the region." [PMID:19416828, PomBase:mah] synonym: "increased level of large Y-shaped DNA replication intermediates" EXACT [PomBase:mah] synonym: "increased level of large-Y replication intermediates during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of large-Y replication intermediates during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-04-11T15:43:34Z [Term] id: FYPO:0005362 name: abnormal mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome recapture is abnormal during metaphase of mitosis. Chromosome recapture is the reattachment of chromosomes which have become detached from the spindle." [GO:1990942, PMID:18256284, PomBase:mah] synonym: "abnormal chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "abnormal kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "abnormal mitotic kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "abnormal mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "abnormal mitotic sister kinetochore recapture" EXACT [GO:1990942] is_a: FYPO:0000030 ! abnormal mitotic chromosome congression created_by: midori creation_date: 2016-04-12T13:12:58Z [Term] id: FYPO:0005363 name: decreased kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle kinetochore microtubule depolymerization, occurs to a lesser extent than normal during mitotic chromosome recapture." [PMID:18256284, PomBase:mah] synonym: "decreased kinetochore microtubule catastrophe during mitotic metaphase chromosome recapture" RELATED [PomBase:mah] synonym: "decreased kinetochore microtubule depolymerisation during mitotic metaphase chromosome recapture" EXACT [PomBase:mah] synonym: "decreased kinetochore microtubule depolymerization chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "decreased kinetochore microtubule depolymerization during kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "decreased kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "decreased kinetochore microtubule shrinkage during mitotic metaphase chromosome recapture" RELATED [Pombase:vw] synonym: "decreased mitotic spindle kinetochore microtubule depolymerization during chromosome recapture" EXACT [PomBase:vw] synonym: "decreased mitotic spindle kinetochore microtubule depolymerization during kinetochore retrieval" EXACT [GO:1990942] synonym: "decreased mitotic spindle kinetochore microtubule depolymerization during metaphase chromosome retrieval to SPB" EXACT [PomBase:mah] synonym: "decreased mitotic spindle kinetochore microtubule depolymerization during metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "decreased mitotic spindle kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture" EXACT [PomBase:vw] synonym: "decreased mitotic spindle kinetochore microtubule depolymerization during sister kinetochore recapture" EXACT [GO:1990942] synonym: "reduced kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture" EXACT [PomBase:mah] is_a: FYPO:0004650 ! decreased mitotic spindle microtubule depolymerization is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2016-04-12T13:18:44Z [Term] id: FYPO:0005364 name: decreased rate of kinetochore sliding during chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of kinetochore sliding, i.e. the movement of a kinetochore along spindle microtubules, during mitotic chromosome recapture is decreased." [PMID:18256284, PomBase:mah] comment: Note that, although the movement affected in this phenotype is often described as "kinetochore migration" or "kinetochore sliding", the entire chromosome moves along the spindle microtubules. synonym: "decreased rate of chromosome migration during chromosome recapture" EXACT [PomBase:vw] synonym: "decreased rate of chromosome movement during chromosome recapture" EXACT [PomBase:vw] synonym: "decreased rate of kinetochore migration during chromosome recapture" EXACT [PomBase:vw] synonym: "decreased rate of kinetochore sliding along kinetochore microtubule towards spindle pole body during chromosome recapture" EXACT [PomBase:vw] synonym: "decreased rate of kinetochore sliding during chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "decreased rate of kinetochore sliding during chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of kinetochore sliding during kinetochore retrieval" EXACT [GO:1990942] synonym: "decreased rate of kinetochore sliding during kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "decreased rate of kinetochore sliding during metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "decreased rate of kinetochore sliding during mitotic metaphase chromosome recapture" EXACT [PomBase:vw] synonym: "decreased rate of kinetochore sliding during sister kinetochore recapture" EXACT [GO:1990942] synonym: "decreased rate of kinetochore sliding towards SPB during chromosome recapture" EXACT [PomBase:vw] synonym: "decreased rate of kinetochore sliding towards spindle pole body during chromosome recapture" EXACT [PomBase:vw] synonym: "reduced rate of kinetochore sliding during chromosome recapture" EXACT [PomBase:mah] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2016-04-12T13:24:32Z [Term] id: FYPO:0005365 name: abolished kinetochore sliding during chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore sliding, i.e. the movement of a kinetochore along spindle microtubules, during mitotic chromosome recapture does not occur." [PMID:18256284, PomBase:mah] comment: Note that, although the movement affected in this phenotype is often described as "kinetochore migration" or "kinetochore sliding", the entire chromosome moves along the spindle microtubules. synonym: "abolished chromosome migration during chromosome recapture" EXACT [PomBase:vw] synonym: "abolished chromosome movement during chromosome recapture" EXACT [PomBase:vw] synonym: "abolished kinetochore migration during chromosome recapture" EXACT [PomBase:vw] synonym: "abolished kinetochore sliding along kinetochore microtubule towards spindle pole body during chromosome recapture" EXACT [PomBase:vw] synonym: "abolished kinetochore sliding during chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "abolished kinetochore sliding during chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "abolished kinetochore sliding during kinetochore retrieval" EXACT [GO:1990942] synonym: "abolished kinetochore sliding during kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "abolished kinetochore sliding during metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "abolished kinetochore sliding during mitotic metaphase chromosome recapture" EXACT [PomBase:vw] synonym: "abolished kinetochore sliding during sister kinetochore recapture" EXACT [GO:1990942] synonym: "abolished kinetochore sliding towards SPB during chromosome recapture" EXACT [PomBase:vw] synonym: "abolished kinetochore sliding towards spindle pole body during chromosome recapture" EXACT [PomBase:vw] synonym: "kinetochore sliding during chromosome recapture abolished" EXACT [PomBase:mah] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2016-04-12T13:27:26Z [Term] id: FYPO:0005366 name: abolished protein phosphorylation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "protein phosphorylation abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-04-12T13:41:52Z [Term] id: FYPO:0005367 name: inviable mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition def: "A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, and progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable mononucleate aseptate cell with mitotic cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell arrested at G2/M" EXACT [PomBase:jh] synonym: "inviable mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell with cell cycle arrest in mitotic G2 phase" RELATED [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell with mitotic cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable mononucleate aseptate vegetative cell with mitotic G2/M phase transition arrest" EXACT [PomBase:vw] synonym: "lethal; mononucleate aseptate vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in G2-phase with inviable mononucleate aseptate cell" RELATED [PomBase:vw] synonym: "mitotic G2-phase arrested inviable mononucleate aseptate vegetative cell" RELATED [PomBase:mah] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition is_a: FYPO:0003763 ! inviable aseptate mononucleate vegetative cell created_by: midori creation_date: 2016-04-12T13:45:38Z [Term] id: FYPO:0005368 name: decreased level of iron ion starvation-induced proteins def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced during iron ion starvation measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased level of iron ion depletion-induced proteins" EXACT [PomBase:vw] synonym: "decreased level of iron ion deprivation-induced proteins" EXACT [PomBase:vw] synonym: "decreased level of iron ion starvation-induced proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of iron ion starvation-induced proteins during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of proteins expressed during iron ion starvation" EXACT [PomBase:mah] synonym: "decreased level of proteins induced by iron ion starvation" EXACT [PomBase:mah] synonym: "decreased protein level of genes (normally) induced during iron starvation" EXACT [PomBase:al] synonym: "reduced level of iron ion starvation-induced proteins" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2016-04-12T13:56:33Z [Term] id: FYPO:0005369 name: abolished cell population growth at low temperature def: "A vegetative cell population growth phenotype in which a cell population does not grow at low temperatures." [PomBase:mah] comment: For fission yeast, low temperature usually corresponds to below 25 degrees Celsius. Use this term for a population of cells that does not grow at low temperature, but does grow at a higher temperature (a cell population that does not grow at any temperature would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished cell population growth at low temperature during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished growth at low temperature" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth at low temperature" EXACT [PomBase:mah] synonym: "cell population growth at low temperature abolished" EXACT [PomBase:mah] synonym: "cold sensitive" RELATED [PomBase:mah] synonym: "hypersensitive to low temperature" RELATED [PomBase:mah] synonym: "sensitive to cold" RELATED [PomBase:mah] synonym: "sensitive to low temperature" RELATED [PomBase:mah] synonym: "sensitive to low temperature during vegetative growth" RELATED [PomBase:mah] synonym: "temperature sensitive" RELATED [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2016-04-12T13:58:16Z [Term] id: FYPO:0005370 name: decreased fidelity of double-strand break repair via nonhomologous end joining def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which occurrence of errors, usually small deletions, upon repair of double-strand breaks in DNA by nonhomologous end joining is increased." [PMID:11226171, PomBase:mah] comment: In wild type S. pombe cells, errors occur in 40-60% of NHEJ-mediated DSB repair events. In mutants with this phenotype, few or no repairs may be free of errors. is_a: FYPO:0003661 ! abnormal double-strand break repair via nonhomologous end joining created_by: midori creation_date: 2016-04-18T14:05:24Z [Term] id: FYPO:0005371 name: increased linear minichromosome loss during vegetative growth def: "A cell phenotype in which linear minichromosomes are lost at a higher frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PMID:11226171, PomBase:mah] synonym: "increased linear minichromosome loss during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic linear minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0001840 ! increased minichromosome loss during vegetative growth created_by: midori creation_date: 2016-04-18T14:08:08Z [Term] id: FYPO:0005372 name: increased circular minichromosome loss during vegetative growth def: "A cell phenotype in which circular minichromosomes are lost at a higher frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation." [PMID:11226171, PomBase:mah] synonym: "increased circular minichromosome loss during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic circular minichromosome maintenance defect" RELATED [PomBase:mah] is_a: FYPO:0001840 ! increased minichromosome loss during vegetative growth created_by: midori creation_date: 2016-04-18T14:11:14Z [Term] id: FYPO:0005373 name: normal mitotic cell cycle regulation during cellular response to methyl methanesulfonate def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to methyl methanesulfonate (MMS) is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to MMS." [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle delay following methyl methanesulfonate exposure" EXACT [PomBase:al] synonym: "normal mitotic cell cycle regulation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to MMS" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation in response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2016-04-18T14:15:36Z [Term] id: FYPO:0005375 name: decreased sister chromatid meiotic recombination def: "A cellular process phenotype in which the occurrence of meiotic recombination between alleles of one sister chromatid (intra-sister recombination) or between alleles on different sister chromatids (inter-sister recombination) is decreased." [PMID:11726502, PomBase:mah] synonym: "reduced sister chromatid meiotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2016-04-18T14:25:43Z [Term] id: FYPO:0005376 name: abnormal proteolysis def: "A cellular process phenotype in which proteolysis is abnormal. Proteolysis is the hydrolysis of one or more peptide bonds within a protein." [GO:0006508, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal peptidolysis" EXACT [GO:0006508, PomBase:mah] synonym: "abnormal protein cleavage" NARROW [PomBase:vw] is_a: FYPO:0002274 ! abnormal protein metabolic process created_by: midori creation_date: 2016-04-25T14:27:49Z [Term] id: FYPO:0005377 name: abolished proteolysis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the hydrolysis of peptide bonds within a protein does not occur. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins." [GO:0006508, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished peptidolysis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein cleavage during vegetative growth" NARROW [PomBase:vw] synonym: "abolished proteolysis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "proteolysis abolished" EXACT [PomBase:mah] is_a: FYPO:0000328 ! abnormal protein metabolic process during vegetative growth is_a: FYPO:0005376 ! abnormal proteolysis created_by: midori creation_date: 2016-04-25T14:28:13Z [Term] id: FYPO:0005378 name: normal spindle pole body organization def: "A cell phenotype in which spindle pole body organization is normal (i.e. indistinguishable from wild type). Spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB)." [GO:0051300, PomBase:mah] synonym: "normal SPB organization" EXACT [PomBase:mah] synonym: "normal spindle pole body organisation" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2016-04-25T15:18:03Z [Term] id: FYPO:0005379 name: normal spindle pole body def: "A physical cellular phenotype in which the spindle pole bodies are normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation." [PomBase:mah] synonym: "normal SPB" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component relationship: output_of FYPO:0005378 ! normal spindle pole body organization created_by: midori creation_date: 2016-04-25T15:19:16Z [Term] id: FYPO:0005380 name: normal mitotic spindle pole body duplication def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body duplication is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitotic SPB duplication" EXACT [PomBase:mah] synonym: "normal mitotic spindle pole body duplication during vegetative growth" EXACT [PomBase:mah] synonym: "normal spindle pole body duplication during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0005378 ! normal spindle pole body organization created_by: midori creation_date: 2016-04-25T15:24:42Z [Term] id: FYPO:0005381 name: asymmetric gamma-tubulin complex localization to single mitotic spindle pole body def: "A cellular process phenotype in which the gamma-tubulin complex is localized to only one spindle pole body instead of both." [PMID:11102508, PomBase:mah] comment: Note that this term has no connection to 'abnormal asymmetric protein localization to old or new mitotic spindle pole body' (FYPO:0001874), because that term refers to abnormalities in a process that normally results in asymmetric localization, whereas for the gamma-tubulin complex, symmetric localization to both SPBs is normal. synonym: "abnormal gamma-tubulin complex localization to single mitotic spindle pole body" EXACT [PomBase:mah] synonym: "abnormally asymmetric gamma-tubulin complex localization to single mitotic spindle pole body" EXACT [PomBase:vw] synonym: "asymmetric gamma-tubulin complex localisation to single mitotic spindle pole body" EXACT [PomBase:mah] synonym: "asymmetric gamma-tubulin complex localization to single mitotic SPB" EXACT [PomBase:mah] synonym: "asymmetric gamma-tubulin complex localization to single mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric gamma-tubulin complex localization to single mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004589 ! abnormal gamma-tubulin complex localization to mitotic spindle pole body created_by: midori creation_date: 2016-04-25T15:34:39Z [Term] id: FYPO:0005382 name: delayed exit from meiosis def: "A cellular process phenotype in which exit from meiosis begins later than normal." [PomBase:mah] synonym: "delayed exit from meiosis II" EXACT [PomBase:mah] synonym: "delayed exit from meiotic nuclear division" EXACT [GO:0140013] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2016-04-25T15:53:32Z [Term] id: FYPO:0005383 name: normal duration of meiosis I def: "A cellular process phenotype in which the duration of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of first meiotic nuclear division" EXACT [GO:0007127] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2016-04-25T16:03:15Z [Term] id: FYPO:0005384 name: meiosis I metaphase/anaphase transition delay def: "A cell cycle phenotype in which the onset of anaphase of the first meiotic nuclear division begins later than normal." [PomBase:mah] synonym: "delayed cell cycle passage through meiosis I metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "delayed metaphase/anaphase transition of meiosis I" EXACT [GO:1990949] synonym: "delayed onset of meiotic anaphase I" EXACT [PomBase:vw] synonym: "increased duration of meiosis I metaphase" RELATED [PomBase:mah] synonym: "increased duration of metaphase during meiosis I" RELATED [PomBase:mah] synonym: "meiotic cell cycle delay at first metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "metaphase/anaphase transition delay during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "metaphase/anaphase transition delay during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0005274 ! abnormal meiotic cell cycle phase transition created_by: midori creation_date: 2016-04-25T16:10:05Z [Term] id: FYPO:0005385 name: abnormal cell cycle arrest in meiotic metaphase I alt_id: FYPO:0006769 def: "A cellular process phenotype in which progression through the first meiotic nuclear division (part of the meiotic cell cycle) is arrested in metaphase under conditions where arrest does not normally occur." [PomBase:mah] comment: Metaphase is defined as the part of mitosis when chromosomes are aligned in the middle of the spindle. If no spindle is present, do not use this term, but consider 'abnormal cell cycle arrest in mitotic prophase' (FYPO:0003145). Also do not use this term if the spindle has elongated at all. If the spindle has elongated, or you cannot tell whether a spindle is present, or metaphase cannot be clearly detected, annotate to the more general term 'abnormal cell cycle arrest in mitotic M phase' (FYPO:0000608). In cells that arrest in metaphase, chromosome separation does not occur. synonym: "abnormal cell cycle arrest in metaphase during first meiotic nuclear division" EXACT [GO:0007127] synonym: "abnormal cell cycle arrest in metaphase I" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in metaphase I during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in metaphase of meiosis I" EXACT [PomBase:mah] synonym: "abnormal meiotic cell cycle arrest in metaphase I" EXACT [PomBase:mah, Pombase:mah] synonym: "abolished meiosis I metaphase/anaphase transition" RELATED [PomBase:mah] is_a: FYPO:0002817 ! abnormally arrested meiosis I relationship: has_output FYPO:0001946 ! abolished mitotic sister chromatid separation created_by: midori creation_date: 2016-04-25T16:39:35Z [Term] id: FYPO:0005386 name: decreased protein localization to chromatin at chromosome arms def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin along chromosome arms is decreased." [PMID:16682348, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at chromosome arms" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin along chromosome arms" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at chromosome arms during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromosome arms during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at chromosome arms" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-04-25T16:44:28Z [Term] id: FYPO:0005387 name: decreased eukaryotic translation initiation factor 2B complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of eukaryotic translation initiation factor 2B complex assembly is decreased." [PomBase:mah] synonym: "decreased eIF-2B assembly" EXACT [GO:1905173] synonym: "decreased eIF-2B formation" EXACT [GO:1905173] synonym: "decreased eif2B assembly" EXACT [GO:1905713] synonym: "decreased eukaryotic translation initiation factor 2B complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased eukaryotic translation initiation factor 2B complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced eukaryotic translation initiation factor 2B complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2016-05-03T14:05:34Z [Term] id: FYPO:0005388 name: decreased number of Rad51 foci during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad51 accumulates is lower than normal during a cellular response to ionizing radiation." [PMID:12023299, PomBase:mah] synonym: "decreased number of Rad51 foci during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Rad51 foci during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased number of Rad51 foci during cellular response to IR" EXACT [PomBase:mah] synonym: "reduced number of Rad51 foci during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2016-05-03T14:10:22Z [Term] id: FYPO:0005389 name: increased number of Rqh1 foci during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rqh1 accumulates is greater than normal during a cellular response to ionizing radiation." [PMID:12023299, PomBase:mah] synonym: "increased number of Rqh1 foci during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rqh1 foci during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rqh1 foci during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2016-05-03T14:12:01Z [Term] id: FYPO:0005390 name: increased punctate nuclear protein localization during cellular response to ionizing radiation def: "A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that more dots are observed than in normal (wild type) cells during a cellular response to ionizing radiation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased punctate nuclear protein localisation during cellular response to ionising radiation" EXACT [PomBase:mah] synonym: "increased punctate nuclear protein localization during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased punctate nuclear protein localization during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased punctate nuclear protein localization during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0005116 ! increased punctate nuclear protein localization created_by: midori creation_date: 2016-05-03T14:14:56Z [Term] id: FYPO:0005391 name: increased DNA recombination during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is increased during a cellular response to ionizing radiation." [PomBase:mah] synonym: "increased DNA recombination during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA recombination during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased DNA recombination during cellular response to IR" EXACT [PomBase:mah] synonym: "increased DNA recombination frequency during cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "increased DNA recombination rate during cellular response to ionizing radiation during vegetative growth" RELATED [PomBase:mah] synonym: "increased recombination during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2016-05-03T14:33:51Z [Term] id: FYPO:0005392 name: normal DNA recombination frequency during cellular response to ionizing radiation def: "A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) during a cellular response to ionizing radiation." [PomBase:mah] synonym: "normal DNA recombination frequency during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA recombination frequency during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal DNA recombination frequency during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-05-03T14:38:15Z [Term] id: FYPO:0005393 name: progressively decreasing vegetative cell population growth rate def: "A cell population phenotype in which vegetative cell population growth is slower than normal, and the population growth rate decreases over successive generations." [PMID:12196391, PomBase:mah] synonym: "progressively decreasing cell population growth rate during vegetative growth" EXACT [PomBase:mah] synonym: "progressively decreasing cell population proliferation" RELATED [PomBase:vw] synonym: "progressively decreasing cell proliferation" RELATED [PomBase:vw] synonym: "progressively reduced cell proliferation" RELATED [PomBase:vw] synonym: "progressively reduced vegetative cell population growth rate" EXACT [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2016-05-03T14:47:17Z [Term] id: FYPO:0005394 name: progressively decreasing vegetative cell population growth rate followed by return to normal growth rate def: "A cell population phenotype in which vegetative cell population growth is slower than normal for several generations, with the population growth rate decreasing over successive generations, after which the population resumes growing at a normal or near-normal rate." [PMID:12196391, PomBase:mah] comment: This population growth pattern is often seen with mutations that affect telomere maintenance. The slowing growth reflects a high rate of cell death as telomeres shorten, and in a small sub-population of cells, chromosomes circularize allowing the population to resume growth at a higher, often normal, rate. synonym: "emergence of telomerase-deficient survivors" RELATED [PomBase:mah] synonym: "progressively decreasing cell population growth rate followed by return to normal growth rate during vegetative growth" EXACT [PomBase:mah] synonym: "progressively decreasing cell population proliferation followed by return to normal proliferation" RELATED [PomBase:vw] synonym: "progressively decreasing cell proliferation followed by return to normal proliferation" RELATED [PomBase:vw] synonym: "progressively reduced cell proliferation followed by return to normal proliferation" RELATED [PomBase:vw] synonym: "progressively reduced vegetative cell population growth rate followed by return to normal growth rate" EXACT [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth relationship: has_part FYPO:0005393 ! progressively decreasing vegetative cell population growth rate created_by: midori creation_date: 2016-05-03T14:48:15Z [Term] id: FYPO:0005395 name: normal protein phosphorylation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-05-03T14:53:42Z [Term] id: FYPO:0005396 name: abolished protein localization to subtelomeric heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to subtelomeric heterochromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to telomeric heterochromatin" RELATED [Pombase:mah, PomBase:vw] synonym: "protein localization to subtelomeric heterochromatin during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2016-05-03T14:55:24Z [Term] id: FYPO:0005397 name: normal intracellular protein transport during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport in the cell is normal (i.e. indistinguishable from wild type)." [GO:0006886, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal intracellular protein transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth created_by: midori creation_date: 2016-05-03T15:02:26Z [Term] id: FYPO:0005398 name: normal frequency of double-strand break repair via homologous recombination def: "A cellular process phenotype in which the frequency of occurrence of double-strand break repair via homologous recombination is normal (i.e. indistinguishable from wild type)." [PMID:12628934, PomBase:mah] synonym: "normal frequency of double-strand break repair via homologous recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal frequency of double-strand break repair via homologous recombination during vegetative growth" EXACT [PomBase:mah] synonym: "normal occurrence of double-strand break repair via homologous recombination" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-05-03T15:22:05Z [Term] id: FYPO:0005399 name: abolished double-strand break repair via homologous recombination def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair via homologous recombination does not occur." [PomBase:mah] synonym: "abolished double-strand break repair via homologous recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished double-strand break repair via homologous recombination during vegetative growth" EXACT [PomBase:mah] synonym: "double-strand break repair via homologous recombination abolished" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2016-05-03T15:23:58Z [Term] id: FYPO:0005400 name: abnormal mitotic cell cycle regulation during cellular response to DNA double-strand break def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to the presence of DNA double-strand breaks is abnormal." [PMID:12628934, PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to DNA double-strand break" EXACT [PomBase:mah] synonym: "abnormal cell cycle regulation during cellular response to DNA double-strand break during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation during cellular response to DNA double-strand break during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle regulation in response to DNA double-strand break" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle created_by: midori creation_date: 2016-05-03T15:26:12Z [Term] id: FYPO:0005401 name: increased protein level during mitotic G1 cell cycle arrest in response to nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell is higher than normal during arrest of the mitotic cell cycle in G1 phase due to nitrogen starvation. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during mitotic G1 cell cycle arrest in response to nitrogen starvation" RELATED [PomBase:mah] synonym: "increased protein level during G1 arrest in response to nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0001219 ! increased protein level during cellular response to nitrogen starvation created_by: midori creation_date: 2016-05-04T10:42:00Z [Term] id: FYPO:0005402 name: increased telomeric 3' overhang length during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the single-stranded telomeric 3' overhang is longer than normal." [PMID:12861005, PomBase:mah] synonym: "increased single-stranded telomeric 3' overhang length during vegetative growth" EXACT [GO:0031860, PomBase:mah] synonym: "increased telomere 3' overhang length during vegetative growth" EXACT [PomBase:mah] synonym: "increased telomeric 3' overhang length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased telomeric G-strand overhang length during vegetative growth" EXACT [PMID:12861005] is_a: FYPO:0002254 ! abnormal telomere morphology during vegetative growth is_a: FYPO:0006510 ! abnormal telomere structure created_by: midori creation_date: 2016-05-04T14:05:20Z [Term] id: FYPO:0005403 name: telomeric 3' overhang absent during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the single-stranded telomeric 3' overhang is not present. Total telomere length may be normal or abnormal." [PMID:12861005, PomBase:mah] synonym: "single-stranded telomeric 3' overhang absent during vegetative growth" EXACT [GO:0031860, PomBase:mah] synonym: "telomere 3' overhang absent during vegetative growth" EXACT [PomBase:mah] synonym: "telomeric 3' overhang absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "telomeric G-strand overhang absent during vegetative growth" EXACT [PMID:12861005] is_a: FYPO:0002254 ! abnormal telomere morphology during vegetative growth is_a: FYPO:0006510 ! abnormal telomere structure created_by: midori creation_date: 2016-05-04T14:09:01Z [Term] id: FYPO:0005404 name: telomeric regions absent from linear chromosomes def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosomes remain linear, but lose telomeric repeats. Subtelomeric DNA may also be lost." [PMID:12930956, PomBase:mah] synonym: "telomeric regions absent from linear chromosomes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "telomeric regions absent from linear chromosomes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2016-05-04T15:34:59Z [Term] id: FYPO:0005405 name: increased DNA recombination at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is increased in telomeric regions." [PMID:12930956, PomBase:mah] comment: Note that this phenotype can be observed in haploid cells that have not undergone meiosis, sporulation and spore germination. synonym: "increased DNA recombination at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA recombination frequency at telomere during vegetative growth" RELATED [PomBase:mah] synonym: "increased DNA recombination rate at telomere during vegetative growth" RELATED [PomBase:mah] synonym: "increased recombination at telomere during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2016-05-04T15:38:05Z [Term] id: FYPO:0005406 name: increased DNA recombination at telomere following meiotic cell cycle def: "A cellular process phenotype in which the occurrence of DNA recombination is increased in telomeric regions in haploid cells that have undergone meiosis, sporulation and spore germination." [PMID:12930956, PomBase:mah] synonym: "increased DNA recombination at telomere during meiotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA recombination frequency at telomere following meiotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA recombination rate at telomere following meiotic cell cycle" RELATED [PomBase:mah] synonym: "increased recombination at telomere following meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2016-05-04T15:39:46Z [Term] id: FYPO:0005407 name: increased DNA recombination at telomere during nitrogen starvation def: "A cellular process phenotype in which the occurrence of DNA recombination is increased in telomeric regions when the cell is subject to nitrogen starvation." [PMID:12930956, PomBase:mah] comment: Note that this phenotype can be observed in haploid cells that have not undergone meiosis, sporulation and spore germination. synonym: "increased DNA recombination at telomere during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased DNA recombination at telomere during nitrogen deprivation" EXACT [PomBase:mah] synonym: "increased DNA recombination frequency at telomere during nitrogen starvation" RELATED [PomBase:mah] synonym: "increased DNA recombination rate at telomere during nitrogen starvation" RELATED [PomBase:mah] synonym: "increased recombination at telomere during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2016-05-04T15:41:07Z [Term] id: FYPO:0005408 name: decreased duration of mitotic S phase during cellular response to methyl methanesulfonate def: "A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is shorter than normal during a cellular response to methyl methanesulfonate." [PomBase:mah] comment: Use this term if the duration of S phase is decreased relative to wild type cells exposed to MMS, no matter how the mutant S phase compares to S phase in untreated wild type cells. synonym: "decreased duration of mitotic S phase during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of mitotic S phase during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "decreased duration of mitotic S phase during cellular response to MMS" EXACT [PomBase:mah] synonym: "decreased duration of S phase during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced duration of mitotic S phase during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0000615 ! decreased duration of mitotic S phase created_by: midori creation_date: 2016-05-10T12:00:52Z [Term] id: FYPO:0005409 name: normal protein level during cell cycle arrest in mitotic G1 phase in response to nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell that has arrested the mitotic cell cycle G1 phase in response to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein level during cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein accumulation during cell cycle arrest in mitotic G1 phase in response to nitrogen starvation" RELATED [PomBase:mah] synonym: "normal protein level during cell cycle arrest in mitotic G1 phase in response to nitrogen depletion" EXACT [PomBase:vw] synonym: "normal protein level during cell cycle arrest in mitotic G1 phase in response to nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal protein level during mitotic G1 arrest in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein level during nitrogen deprivation-induced G1 arrest" EXACT [PomBase:vw] is_a: FYPO:0004084 ! normal protein level during nitrogen starvation created_by: midori creation_date: 2016-05-13T13:14:57Z [Term] id: FYPO:0005410 name: normal protein degradation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) during mitosis. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein breakdown during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism during mitosis" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein degradation during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein degradation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein degradation during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein degradation during mitotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002799 ! normal protein degradation created_by: midori creation_date: 2016-05-13T13:28:33Z [Term] id: FYPO:0005411 name: increased number of unattached kinetochores def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore results in a larger number of kinetochores remaining unattached than normal." [PMID:18256284, PomBase:mah, PomBase:vw] synonym: "abnormal attachment of mitotic spindle microtubules to kinetochore resulting in increased number of unattached kinetochores" EXACT [PomBase:mah] synonym: "decreased attachment of mitotic spindle microtubules to kinetochore" RELATED [PomBase:mah] synonym: "increased number of unattached kinetochores during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of unattached kinetochores during vegetative growth" EXACT [PomBase:mah] synonym: "kinetochore loss" RELATED [PomBase:vw] is_a: FYPO:0004213 ! abnormal attachment of mitotic spindle microtubules to kinetochore created_by: midori creation_date: 2016-05-13T13:40:01Z [Term] id: FYPO:0005412 name: delayed onset of meiosis II def: "A cellular process phenotype in which the second meiotic nuclear division begins later than normal." [PomBase:mah] synonym: "delayed meiosis II" EXACT [PomBase:mah] synonym: "delayed onset of second meiotic nuclear division" EXACT [GO:0007127] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2016-05-13T14:05:45Z [Term] id: FYPO:0005413 name: increased protein level during meiosis I def: "A cell phenotype in which the amount of protein measured in a cell during the first meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during meiosis I" RELATED [PomBase:mah] synonym: "increased protein level during first meiotic nuclear division" EXACT [PomBase:vw] is_a: FYPO:0003611 ! increased protein level during meiosis created_by: midori creation_date: 2016-05-13T14:13:01Z [Term] id: FYPO:0005414 name: increased protein level during meiosis II def: "A cell phenotype in which the amount of protein measured in a cell during the second meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during meiosis II" RELATED [PomBase:mah] synonym: "increased protein level during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003611 ! increased protein level during meiosis created_by: midori creation_date: 2016-05-13T14:13:47Z [Term] id: FYPO:0005415 name: increased protein level during meiotic anaphase I def: "A cell phenotype in which the amount of protein measured in a cell during anaphase of the first meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during meiotic anaphase I" RELATED [PomBase:mah] synonym: "increased protein level during first meiotic anaphase" EXACT [PomBase:vw] is_a: FYPO:0005413 ! increased protein level during meiosis I created_by: midori creation_date: 2016-05-13T14:25:04Z [Term] id: FYPO:0005416 name: increased protein level during meiotic anaphase II def: "A cell phenotype in which the amount of protein measured in a cell during anaphase of the second meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during meiotic anaphase II" RELATED [PomBase:mah] synonym: "increased protein level during second meiotic anaphase" EXACT [PomBase:vw] is_a: FYPO:0005414 ! increased protein level during meiosis II created_by: midori creation_date: 2016-05-13T14:26:54Z [Term] id: FYPO:0005417 name: premature mitotic spindle elongation def: "A cellular process phenotype in which mitotic spindle elongation begins earlier than normal." [PomBase:mah] synonym: "advanced mitotic spindle elongation" EXACT [PomBase:mah] synonym: "premature mitotic sister chromatid separation during vegetative growth" RELATED [PomBase:mah] synonym: "premature spindle elongation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation created_by: midori creation_date: 2016-05-13T14:29:34Z [Term] id: FYPO:0005418 name: abolished ATPase activator activity def: "A molecular function phenotype in which a gene product (usually a protein) that normally has ATPase activator activity has no activity in a mutant. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any ATPase activator activity that is abolished by a mutation, whether or not the mutated gene product normally acts as an ATPase activator. synonym: "ATPase activator activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0007690 ! catalytic activity regulator phenotype created_by: midori creation_date: 2016-05-13T14:33:16Z [Term] id: FYPO:0005419 name: abnormal mitochondrial crista morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitochondrial cristae is abnormal." [PomBase:mah] synonym: "abnormal mitochondrial crista morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitochondrial crista morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitochondrial cristae morphology" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology created_by: midori creation_date: 2016-05-13T14:48:39Z [Term] id: FYPO:0005420 name: increased level of iron assimilation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased iron assimilation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of iron assimilation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of iron assimilation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of iron assimilation gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2016-05-13T14:50:34Z [Term] id: FYPO:0005421 name: obsolete inviable elongated vegetative cell with mitotic cell cycle arrest in interphase during cellular response to UV def: "OBSOLETE. A cell morphology phenotype in which a vegetative cell is inviable and elongated, and progression through the mitotic cell cycle is arrested in interphase, during a cellular response to ultraviolet light. The cell contains no septum." [PomBase:mah] comment: This term was made obsolete because the phenotype would be better represented by annotating to the arrest/morphology term with conditions specified. synonym: "elongated inviable cell with mitotic cell cycle arrest in interphase during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell with mitotic cell cycle arrest in interphase during cellular response to UV" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest in interphase during cellular response to UV" EXACT [PomBase:vw] synonym: "inviable elongated vegetative cell with cell cycle arrest in interphase during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated vegetative cell with mitotic cell cycle arrest in interphase during cellular response to UV" EXACT [PomBase:mah] synonym: "mitotic interphase arrested elongated inviable vegetative cell during cellular response to UV" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2016-06-06T11:45:15Z [Term] id: FYPO:0005422 name: inviable elongated cell with fragmented nucleus and mitotic cell cycle arrest in interphase during cellular response to UV def: "A cell morphology phenotype in which a vegetative cell is inviable and elongated, has a nucleus that is broken into multiple small fragments, and progression through the mitotic cell cycle is arrested in interphase during a cellular response to ultraviolet light. The cell contains no septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell with fragmented nucleus and mitotic cell cycle arrest in interphase during cellular response to UV during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase during cellular response to UV" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with fragmented nucleus and cell cycle arrest in mitotic interphase during cellular response to UV" EXACT [PomBase:vw] synonym: "inviable elongated vegetative cell with fragmented nuclear DNA and mitotic cell cycle arrest in interphase during cellular response to UV" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus and cell cycle arrest in interphase during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase during cellular response to UV" EXACT [PomBase:mah] synonym: "inviable elongated vegetative cell with fragmented nucleus and mitotic interphase arrest during cellular response to UV" EXACT [PomBase:vw] synonym: "lethal; elongated vegetative cell with fragmented nucleus and mitotic cell cycle arrest in interphase during cellular response to UV" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in interphase and elongated inviable cell with fragmented nucleus during cellular response to UV" EXACT [PomBase:vw] synonym: "mitotic interphase arrested elongated inviable vegetative cell during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0004197 ! inviable elongated cell with fragmented nucleus and mitotic cell cycle arrest in interphase created_by: midori creation_date: 2016-06-06T11:48:30Z [Term] id: FYPO:0005423 name: decreased mitotic spindle microtubule depolymerization during mitotic anaphase A def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule in the mitotic spindle, occurs to a lesser extent than normal during anaphase A." [PomBase:mah] synonym: "decreased mitotic spindle microtubule catastrophe during anaphase A" RELATED [PomBase:mah] synonym: "decreased mitotic spindle microtubule depolymerisation during anaphase A" EXACT [PomBase:mah] synonym: "decreased mitotic spindle microtubule depolymerization during anaphase A during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic spindle microtubule depolymerization during movement of chromosomes towards separated spindle pole bodies" EXACT [PomBase:vw] synonym: "decreased mitotic spindle microtubule shrinkage during anaphase A" RELATED [PomBase:vw] synonym: "decreased spindle microtubule depolymerization during anaphase A during mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced mitotic spindle microtubule depolymerization during anaphase A" EXACT [PomBase:mah] is_a: FYPO:0004650 ! decreased mitotic spindle microtubule depolymerization created_by: midori creation_date: 2016-06-06T12:02:49Z [Term] id: FYPO:0005424 name: decreased mitotic chromosome condensation during telophase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation occurs to a lower extent than normal during telophase of mitosis." [PomBase:mah] synonym: "decreased chromosome condensation during mitotic telophase" EXACT [PomBase:mah] synonym: "decreased mitotic chromosome condensation at telophase" EXACT [PomBase:vw] synonym: "decreased mitotic chromosome condensation during telophase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitotic chromosome condensation during telophase" EXACT [PomBase:mah] is_a: FYPO:0003286 ! decreased mitotic chromosome condensation created_by: midori creation_date: 2016-06-06T12:06:18Z [Term] id: FYPO:0005425 name: curved elongated vegetative cell with long curved interphase microtubules def: "A cell morphology phenotype in which a vegetatively growing cell is elongated, is curved along the long axis, and contains cytoplasmic microtubules that are longer than normal and curved. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] comment: In these cells, cytoplasmic microtubules often become long enough to loop around the ends of the cell. synonym: "curved elongated cell with elongated curved interphase microtubules" EXACT [PomBase:mah] synonym: "curved elongated cell with long curved interphase microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "curved elongated vegetative cell with long curved cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "curved elongated vegetative cell with long curved interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "curved elongated vegetative cell with long curved interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0005103 ! curved elongated vegetative cell relationship: has_part FYPO:0004863 ! long curved microtubules created_by: midori creation_date: 2016-06-06T13:05:53Z [Term] id: FYPO:0005426 name: elongated C-shaped vegetative cell with long curved interphase microtubules def: "A cell morphology phenotype in which a vegetatively growing cell is elongated, is curved along the long axis to form a \"C\" shape, and contains cytoplasmic microtubules that are longer than normal and curved. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a C-shaped cell, the curve is centered at the midpoint of the long axis of the cell. Microtubules curve around the ends of the cell and may become long enough to form loops." [PMID:11739790, PomBase:mah, PomBase:vw] synonym: "curved elongated C-shaped vegetative cell with long curved interphase microtubules" EXACT [PomBase:mah] synonym: "elongated C-shaped cell with elongated curved interphase microtubules" EXACT [PomBase:mah] synonym: "elongated C-shaped cell with long curved interphase microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "elongated C-shaped vegetative cell with long curved cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "elongated C-shaped vegetative cell with long curved interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "elongated C-shaped vegetative cell with long curved interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005425 ! curved elongated vegetative cell with long curved interphase microtubules is_a: FYPO:0005789 ! C-shaped vegetative cell relationship: has_part FYPO:0005789 ! C-shaped vegetative cell created_by: midori creation_date: 2016-06-06T13:07:32Z [Term] id: FYPO:0005427 name: elongated J-shaped vegetative cell with curved interphase microtubules def: "A cell morphology phenotype in which a vegetatively growing cell is elongated, is curved along the long axis to form a \"J\" shape, and contains cytoplasmic microtubules that curve to follow the long axis of the cell. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a J-shaped cell, the curve is centered away from the midpoint of the long axis of the cell." [PMID:11739790, PomBase:mah, PomBase:vw] comment: Microtubules in these cells are longer than in wild-type cells, but they are not regarded as elongated because they are normal in proportion to cell length. synonym: "curved elongated J-shaped vegetative cell with curved cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "elongated J-shaped cell with curved cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "elongated J-shaped cell with curved interphase microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "elongated J-shaped vegetative cell with curved cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "elongated J-shaped vegetative cell with curved interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "elongated J-shaped vegetative cell with curved interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003327 ! curved interphase microtubules is_a: FYPO:0005425 ! curved elongated vegetative cell with long curved interphase microtubules is_a: FYPO:0005790 ! J-shaped vegetative cell relationship: has_part FYPO:0003327 ! curved interphase microtubules relationship: has_part FYPO:0005790 ! J-shaped vegetative cell created_by: midori creation_date: 2016-06-06T13:13:04Z [Term] id: FYPO:0005428 name: delayed onset of UV-damage excision repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair begins later than normal. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [GO:0070914, PMID:15329725, PomBase:mah] synonym: "delayed onset of cyclobutane pyrimidine dimer repair" NARROW [GO:0070914] synonym: "delayed onset of pyrimidine-pyrimidone 6-4 photoproduct repair" NARROW [GO:0070914] synonym: "delayed onset of removal of 6-4 photoproducts" NARROW [GO:0070914, PomBase:vw] synonym: "delayed onset of removal of cyclobutane pyrimidine dimers" NARROW [GO:0070914, PomBase:vw] synonym: "delayed onset of UV-damage excision repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of UV-damage excision repair during vegetative growth" EXACT [PomBase:mah] synonym: "delayed UV-damage excision repair" EXACT [PomBase:mah] is_a: FYPO:0000188 ! abnormal DNA repair during vegetative growth created_by: midori creation_date: 2016-06-06T13:28:39Z [Term] id: FYPO:0005429 name: decreased UV-damage excision repair during mitotic G2 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair occurs to a lower extent than normal during G2 phase of the mitotic cell cycle. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [GO:0070914, PomBase:mah] synonym: "decreased UV-damage excision repair during G2 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased UV-damage excision repair during mitotic G2 during vegetative growth" EXACT [PomBase:mah] synonym: "reduced UV-damage excision repair during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0004031 ! decreased UV-damage excision repair created_by: midori creation_date: 2016-06-06T13:32:35Z [Term] id: FYPO:0005430 name: aggregated actin cortical patches during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches cluster together more than normal." [PMID:8522609, PomBase:mah] synonym: "actin cortical patch aggregation during vegetative growth" RELATED [PomBase:mah] synonym: "aggregated actin cortical patch distribution during vegetative growth" EXACT [PomBase:vw] synonym: "aggregated actin cortical patch localisation during vegetative growth" EXACT [PomBase:mah] synonym: "aggregated actin cortical patch localization during vegetative growth" EXACT [PomBase:vw] synonym: "aggregated actin cortical patches during mitotic cell cycle" RELATED [PomBase:mah] synonym: "aggregated actin patches during vegetative growth" EXACT [PomBase:mah] synonym: "aggregated F-actin patches during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003988 ! mislocalized actin cortical patches during vegetative growth created_by: midori creation_date: 2016-06-06T14:20:48Z [Term] id: FYPO:0005431 name: decreased mitotic recombination at hotspot def: "A cellular process phenotype in which the occurrence of mitotic recombination at one or more recombination hotspots is decreased to the background level. The basal rate of recombination (i.e. away from hotspots) may remain normal or may be decreased." [PMID:12019258, PomBase:mah] synonym: "decreased mitotic recombination at hotspot during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic recombination at hotspot during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic recombination at recombination hotspot" EXACT [PomBase:mah] synonym: "hotspot-specific decreased mitotic recombination" EXACT [PomBase:mah] synonym: "reduced mitotic recombination at hotspot" EXACT [PomBase:mah] is_a: FYPO:0000482 ! decreased mitotic recombination created_by: midori creation_date: 2016-06-13T13:50:35Z [Term] id: FYPO:0005432 name: globally decreased mitotic recombination def: "A cellular process phenotype in which the occurrence of mitotic recombination is decreased both at recombination hotspots and elsewhere in the genome." [PMID:12019258, PomBase:mah] synonym: "globally decreased mitotic recombination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "globally decreased mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "globally reduced mitotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000482 ! decreased mitotic recombination created_by: midori creation_date: 2016-06-13T13:58:52Z [Term] id: FYPO:0005433 name: decreased meiotic recombination at hotspot def: "A cellular process phenotype in which the occurrence of meiotic recombination at one or more recombination hotspots is decreased to the background level. The basal rate of recombination (i.e. away from hotspots) may remain normal or may be decreased." [PMID:12019258, PomBase:mah] synonym: "decreased meiotic recombination at recombination hotspot" EXACT [PomBase:mah] synonym: "hotspot-specific decreased meiotic recombination" EXACT [PomBase:mah] synonym: "reduced meiotic recombination at hotspot" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2016-06-13T14:00:11Z [Term] id: FYPO:0005434 name: globally decreased meiotic recombination def: "A cellular process phenotype in which the occurrence of meiotic recombination is decreased both at recombination hotspots and elsewhere in the genome." [PMID:12019258, PomBase:mah] synonym: "globally reduced meiotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000485 ! decreased meiotic recombination created_by: midori creation_date: 2016-06-13T14:20:51Z [Term] id: FYPO:0005435 name: inviable after spore germination with elongated germ tube and fragmented nucleus def: "A phenotype in which a spore germinates to produce a cell that has an elongated germ tube and a nucleus that is broken into multiple small fragments, and does not go on to give rise to a viable cell population." [PomBase:mah] synonym: "inviable after spore germination with elongated germ tube and fragmented nuclear DNA" RELATED [PomBase:mah] synonym: "inviable after spore germination with elongated germ tube and fragmented nuclear material" EXACT [PomBase:mah] synonym: "inviable after spore germination with elongated germ tube and fragmented nuclei" EXACT [PomBase:mah] synonym: "inviable after spore germination, elongated cell with fragmented nucleus" EXACT [PomBase:mah] synonym: "inviable following spore germination with elongated germ tube and fragmented nucleus" EXACT [PomBase:mah] synonym: "inviable germinated spore with elongated germ tube and fragmented nucleus" EXACT [PomBase:mah] synonym: "lethal after spore germination with elongated germ tube and fragmented nucleus" EXACT [PomBase:mah] is_a: FYPO:0000314 ! inviable after spore germination with elongated germ tube created_by: midori creation_date: 2016-06-13T14:27:49Z [Term] id: FYPO:0005436 name: abolished double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair does not occur." [PomBase:mah] synonym: "abolished double-strand break repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished double-strand break repair during vegetative growth" EXACT [PomBase:mah] synonym: "double-strand break repair abolished" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2016-06-13T14:36:13Z [Term] id: FYPO:0005437 name: normal number of Rad52 foci during cellular response to bleomycin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type) during a cellular response to bleomycin." [PMID:17178839, PomBase:mah] synonym: "normal number of Rad22 foci during cellular response to bleomycin" EXACT [PomBase:mah] synonym: "normal number of Rad52 foci during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal number of Rad52 foci during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] synonym: "normal number of Rad52 foci during cellular response to DNA damage" RELATED [PomBase:mah] is_a: FYPO:0007328 ! normal number of Rad52 foci during vegetative growth created_by: midori creation_date: 2016-06-13T14:42:13Z [Term] id: FYPO:0005438 name: abnormal DNA/DNA annealing activity def: "A molecular function phenotype in which the observed rate of DNA/DNA annealing activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2016-06-15T12:45:36Z [Term] id: FYPO:0005439 name: decreased DNA/DNA annealing activity def: "A molecular function phenotype in which the observed rate of DNA/DNA annealing activity is decreased." [PomBase:mah] synonym: "reduced DNA/DNA annealing activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005438 ! abnormal DNA/DNA annealing activity created_by: midori creation_date: 2016-06-15T12:46:09Z [Term] id: FYPO:0005440 name: swollen elongated cell with enlarged nucleus def: "A cell morphology phenotype in which a vegetative cell is swollen, is elongated, and in which the nucleus is larger than normal. The cell contains one nucleus and no septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PMID:12653962, PomBase:mah, PomBase:vw] comment: The distinction between this phenotype and centrally constricted (dumbbell-shaped) cells (FYPO:0000779) is that swollen elongated cells do not have a constriction along the long axis. Swollen elongated cells may have a uniform diameter, or may be swollen only around the nucleus. This phenotype is usually seen in diploid cells, so consider also annotating to 'increased spontaneous diploidization' (FYPO:0000252). synonym: "elongated cell with enlarged nucleus and increased cell volume" EXACT [PomBase:mah] synonym: "enlarged elongated cell with enlarged nucleus" RELATED [PomBase:mah] synonym: "large elongated cell with enlarged nucleus" RELATED [PomBase:vw] synonym: "swollen elongated mononucleate aseptate cell with enlarged nucleus" EXACT [PomBase:vw] synonym: "swollen elongated vegetative cell with enlarged nucleus" EXACT [PomBase:mah] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0000344 ! enlarged nucleus during vegetative growth is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0000949 ! aseptate is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0001429 ! swollen elongated cell created_by: midori creation_date: 2016-06-15T13:34:38Z [Term] id: FYPO:0005441 name: abolished protein localization to microtubule during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubules does not occur during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to microtubule during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein absent from microtubule during mitotic interphase" RELATED [PomBase:mah] synonym: "protein localization to microtubule abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0003269 ! abolished protein localization to microtubule during vegetative growth created_by: midori creation_date: 2016-06-15T14:07:06Z [Term] id: FYPO:0005442 name: abnormal telomeric DNA separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation is abnormal at the telomeric regions. The remainder of the sister chromatids may or may not separate normally." [PMID:21540296, PomBase:mah] synonym: "abnormal DNA separation at telomere" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid separation at telomere" EXACT [PomBase:mah] synonym: "abnormal mitotic telomeric DNA separation" EXACT [PomBase:vw] synonym: "abnormal segregation of telomeric DNA" RELATED [PomBase:mah] synonym: "abnormal telomere separation" EXACT [PomBase:mah] synonym: "abnormal telomeric DNA separation during mitosis" EXACT [PomBase:mah] synonym: "abnormal telomeric DNA separation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal telomeric DNA separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2016-06-15T14:23:54Z [Term] id: FYPO:0005443 name: decreased proteolysis during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of hydrolysis of peptide bonds within a protein is decreased. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased peptidolysis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein cleavage during vegetative growth" RELATED [PomBase:mah] synonym: "decreased proteolysis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced proteolysis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000545 ! decreased protein modification during vegetative growth is_a: FYPO:0006527 ! decreased proteolysis created_by: midori creation_date: 2016-06-17T14:38:16Z [Term] id: FYPO:0005444 name: slow vegetative cell population growth followed by return to normal growth rate def: "A cell population phenotype in which vegetative cell population growth is initially slower than normal, and remains slow for several generations, after which the population resumes growing at a normal or near-normal rate." [PMID:17429064, PomBase:mah] comment: This population growth pattern is often seen with mutations that affect telomere maintenance. synonym: "decreased cell population proliferation followed by return to normal proliferation" RELATED [PomBase:vw] synonym: "decreased cell proliferation followed by return to normal proliferation" RELATED [PomBase:vw] synonym: "reduced cell proliferation followed by return to normal proliferation" RELATED [PomBase:vw] synonym: "slow cell population growth followed by return to normal growth rate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001234 ! slow vegetative cell population growth relationship: has_part FYPO:0001234 ! slow vegetative cell population growth created_by: midori creation_date: 2016-06-17T14:41:29Z [Term] id: FYPO:0005445 name: normal telomere 3' overhang length during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the length of the single-stranded telomeric 3' overhang is normal (i.e. indistinguishable from wild type)." [PMID:17429064, PomBase:mah] synonym: "normal telomere 3' overhang length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth relationship: part_of FYPO:0002155 ! normal telomere structure during vegetative growth created_by: midori creation_date: 2016-06-17T14:47:52Z [Term] id: FYPO:0005446 name: abolished molecular function def: "A phenotype in which a specific molecular function is absent." [PomBase:mah] subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "molecular function abolished" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2016-06-20T11:37:00Z [Term] id: FYPO:0005447 name: abnormal biological process def: "A phenotype in which a specific biological process is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000300 ! biological process phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2016-06-20T11:43:22Z [Term] id: FYPO:0005448 name: abolished biological process def: "A phenotype in which a specific biological process does not occur." [PomBase:mah] synonym: "biological process abolished" EXACT [PomBase:mah] is_a: FYPO:0005447 ! abnormal biological process created_by: midori creation_date: 2016-06-20T11:46:31Z [Term] id: FYPO:0005449 name: abolished cellular process def: "A phenotype in which a specific cellular process does not occur." [PomBase:mah] synonym: "cellular process abolished" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0005448 ! abolished biological process created_by: midori creation_date: 2016-06-20T11:47:37Z [Term] id: FYPO:0005450 name: normal growth on okadaic acid def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing okadaic acid." [PomBase:mah] synonym: "normal cell population growth in presence of okadaic acid" EXACT [PomBase:mah] synonym: "normal cell population growth on okadaic acid" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to okadaic acid" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on okadaic acid" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2016-06-20T11:52:19Z [Term] id: FYPO:0005451 name: decreased break-induced loss of heterozygosity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one of two different alleles of a gene is lost less frequently than normal after a double-strand break forms nearby." [PMID:17724078, PomBase:mah] comment: This phenotype may be observed in diploid cells, or in cells that have two copies of one or more reporter loci but are otherwise haploid. synonym: "decreased break-induced loss of heterozygosity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased break-induced loss of heterozygosity during vegetative growth" EXACT [PomBase:mah] synonym: "reduced break-induced loss of heterozygosity" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-06-22T15:42:50Z [Term] id: FYPO:0005452 name: increased break-induced loss of heterozygosity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one of two different alleles of a gene is lost more frequently than normal after a double-strand break forms nearby." [PMID:17724078, PomBase:mah] comment: This phenotype may be observed in diploid cells, or in cells that have two copies of one or more reporter loci but are otherwise haploid. synonym: "increased break-induced loss of heterozygosity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased break-induced loss of heterozygosity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-06-22T15:45:01Z [Term] id: FYPO:0005453 name: abolished break-induced loss of heterozygosity via chromosomal translocation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal translocation that would result in the loss of one of two different alleles of a gene does not occur." [PMID:17724078, PomBase:mah] comment: This phenotype may be observed in diploid cells, or in cells that have two copies of one or more reporter loci but are otherwise haploid. Loss of heterozygosity associated with chromosomal translocation may result from allelic crossover or break-induced replication. In cells with this phenotype, loss of heterozygosity may or may not occur via a different mechanism, such as chromosomal truncation. synonym: "abolished break-induced loss of heterozygosity via chromosomal translocation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished break-induced loss of heterozygosity via chromosomal translocation during vegetative growth" EXACT [PomBase:mah] synonym: "break-induced loss of heterozygosity via chromosomal translocation abolished" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype is_a: FYPO:0003037 ! abnormal cell phenotype created_by: midori creation_date: 2016-06-22T15:47:13Z [Term] id: FYPO:0005454 name: abnormal telomere assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere assembly, i.e. the aggregation, arrangement and bonding together of a set of components to form a telomere at a double-stranded DNA end, is abnormal." [GO:0032202, PomBase:mah] synonym: "abnormal telomere assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal telomere assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2016-06-22T15:53:00Z [Term] id: FYPO:0005455 name: telomere assembly at double-strand break site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere assembly occurs at one or more chromosome ends generated by a double-strand break." [PMID:17724078, PomBase:mah] comment: This phenotype can lead to loss of heterozygosity at loci near the break. synonym: "de novo telomere addition at double-strand break site" EXACT [PMID:17724078] synonym: "telomere assembly at double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "telomere assembly at double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "telomere formation at double-strand break site" EXACT [PomBase:mah] is_a: FYPO:0005454 ! abnormal telomere assembly created_by: midori creation_date: 2016-06-22T15:54:06Z [Term] id: FYPO:0005456 name: decreased number of cells with 1C DNA content def: "A cell population phenotype in which a lower than normal number of cells contain 1C DNA content." [PomBase:al] synonym: "decreased amount of cells with 1C DNA content" EXACT [PomBase:al] synonym: "decreased number of cells containing 1C DNA" EXACT [PomBase:al] synonym: "reduced number of cells with 1C DNA content" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2016-06-22T16:04:20Z [Term] id: FYPO:0005457 name: decreased cellular glycerol level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to osmotic stress is lower than normal." [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glycerol accumulation during cellular response to osmotic stress" RELATED [PomBase:al] synonym: "reduced cellular glycerol level during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0002812 ! decreased cellular glycerol level created_by: midori creation_date: 2016-06-24T13:14:55Z [Term] id: FYPO:0005458 name: decreased cellular glycerol level during cellular response to non-ionic osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to non-ionic osmotic stress is lower than normal." [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to non-ionic osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to non-ionic osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular glycerol level during cellular response to sorbitol" RELATED [PomBase:mah] synonym: "decreased glycerol accumulation during cellular response to non-ionic osmotic stress" RELATED [PomBase:al] synonym: "reduced cellular glycerol level during cellular response to non-ionic osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0002812 ! decreased cellular glycerol level created_by: midori creation_date: 2016-06-24T13:17:54Z [Term] id: FYPO:0005459 name: abolished double-strand break repair via nonhomologous end joining def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair via nonhomologous end joining (NHEJ) does not occur." [PomBase:mah] synonym: "abolished double-strand break repair via NHEJ" EXACT [GO:0006303] synonym: "abolished double-strand break repair via nonhomologous end joining during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished double-strand break repair via nonhomologous end joining during vegetative growth" EXACT [PomBase:mah] synonym: "double-strand break repair via nonhomologous end joining abolished" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth created_by: midori creation_date: 2016-06-24T13:49:39Z [Term] id: FYPO:0005460 name: abolished protein localization to chromatin at MCB promoters def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at MCB promoters during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB promoters during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB target genes" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB-containing promoters" EXACT [PomBase:mah] synonym: "protein localization to chromatin at MCB promoters during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth is_a: FYPO:0008249 ! decreased protein localization to chromatin at protein coding gene created_by: midori creation_date: 2016-06-24T13:51:59Z [Term] id: FYPO:0005461 name: abnormal microtubule-based movement during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule-based movement is abnormal." [PomBase:mah] synonym: "abnormal microtubule-based movement during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0007163 ! abnormal microtubule-based movement created_by: midori creation_date: 2016-06-29T12:55:28Z [Term] id: FYPO:0005462 name: decreased microtubule-based movement during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule-based movement occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased microtubule-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced microtubule-based movement during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005461 ! abnormal microtubule-based movement during vegetative growth created_by: midori creation_date: 2016-06-29T12:55:35Z [Term] id: FYPO:0005463 name: decreased spatial extent of interphase microtubule polymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a cytoplasmic microtubule during interphase of the mitotic cell cycle, does not continue until microtubules reach the ends of the cell." [PMID:12894167, PomBase:mah] synonym: "decreased growth of interphase microtubules to cell end" EXACT [PomBase:vw] synonym: "decreased spatial extent of cytoplasmic microtubule polymerization during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased spatial extent of interphase cytoplasmic microtubule polymerization" EXACT [PomBase:mah] synonym: "decreased spatial extent of interphase microtubule growth" EXACT [PomBase:vw] synonym: "decreased spatial extent of interphase microtubule polymerisation" EXACT [PomBase:mah] synonym: "decreased spatial extent of interphase microtubule polymerization" RELATED [PomBase:mah] is_a: FYPO:0004614 ! abnormal microtubule polymerization during vegetative growth relationship: has_output FYPO:0006103 ! short interphase microtubules created_by: midori creation_date: 2016-06-29T13:01:56Z [Term] id: FYPO:0005464 name: abnormal maintenance of protein location at cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to one or both cell tip(s), but then remains there for a longer or shorter time than normal." [PMID:12894167, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal maintenance of protein localization at cell tip during vegetative growth" EXACT [GO:0099017] synonym: "abnormal maintenance of protein location at cell end during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal maintenance of protein location at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "unstable protein localisation to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "unstable protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2016-06-29T13:38:50Z [Term] id: FYPO:0005465 name: normal cell polarity def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Use this term if all aspects of cell polarity are normal, including selection of polarity landmark sites, and polar growth at landmarks. synonym: "normal cell polarity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell polarity during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell polarity process" EXACT [PomBase:mah] synonym: "normal establishment or maintenance of cell polarity" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-06-29T14:18:04Z [Term] id: FYPO:0005466 name: protein mislocalized to non-growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the non-growing cell tip is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at the non-growing cell tip in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to non-growing cell tip" EXACT [PomBase:vw] synonym: "protein mislocalised to non-growing cell tip" EXACT [PomBase:mah] synonym: "protein mislocalised to non-growing cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to non-growing cell end" EXACT [PomBase:mah] synonym: "protein mislocalized to non-growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to non-growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003527 ! protein mislocalized to cell tip created_by: midori creation_date: 2016-06-29T14:26:24Z [Term] id: FYPO:0005467 name: decreased protein localization to actomyosin contractile ring during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actomyosin contractile ring during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring during mitotic nuclear division" EXACT [GO:0140014] synonym: "decreased protein localization to actomyosin contractile ring involved in mitotic cytokinesis during mitosis" EXACT [GO:1904498] synonym: "decreased protein localization to cytokinetic contractile ring during mitosis" EXACT [PomBase:vw] synonym: "decreased protein localization to mitotic contractile ring during mitosis" EXACT [PomBase:vw] synonym: "decreased protein recruitment to actomyosin contractile ring during mitosis" RELATED [PomBase:vw] synonym: "reduced protein localization to actomyosin contractile ring during mitosis" EXACT [PomBase:mah] is_a: FYPO:0002699 ! decreased protein localization to actomyosin contractile ring created_by: midori creation_date: 2016-06-29T14:19:29Z [Term] id: FYPO:0005468 name: increased protein localization to cell tip during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is increased during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell tip during mitosis" EXACT [PomBase:mah] synonym: "increased protein localization to cell end during mitosis" EXACT [PomBase:mah] synonym: "increased protein localization to cell tip during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to cell tip during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to cell tip during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein localization to cell tip during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0002852 ! increased protein localization to cell tip during vegetative growth created_by: midori creation_date: 2016-06-29T14:33:07Z [Term] id: FYPO:0005469 name: inviable after spore germination, without cell division, lysed cell def: "A phenotype in which a spore germinates to produce an inviable cell that does not divide, and eventually lyses." [PMID:8978670, PomBase:mah] synonym: "inviable after spore germination, undivided lysed cell" EXACT [PomBase:mah] synonym: "inviable following spore germination, without cell division, with cell lysis" EXACT [PomBase:mah] synonym: "inviable germinated spore, without cell division, with cell lysis" EXACT [PomBase:mah] synonym: "lethal after spore germination, without cell division, with cell lysis" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2016-06-29T14:40:22Z [Term] id: FYPO:0005470 name: abnormal glutamate synthase (NADH) activity def: "A molecular function phenotype in which the observed rate of glutamate synthase activity using NADH as a cofactor is abnormal." [PomBase:mah] synonym: "abnormal glutamate (reduced nicotinamide adenine dinucleotide) synthase" EXACT [GO:0016040] synonym: "abnormal L-glutamate synthase (NADH) activity" EXACT [GO:0016040] synonym: "abnormal NADH-dependent glutamate synthase activity" EXACT [GO:0016040] synonym: "abnormal NADH: GOGAT activity" RELATED [GO:0016040] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-07-04T13:48:15Z [Term] id: FYPO:0005471 name: abolished glutamate synthase (NADH) activity def: "A molecular function phenotype in which glutamate synthase activity using NADH as a cofactor is absent." [PomBase:mah] synonym: "abolished glutamate (reduced nicotinamide adenine dinucleotide) synthase" EXACT [GO:0016040] synonym: "abolished L-glutamate synthase (NADH) activity" EXACT [GO:0016040] synonym: "abolished NADH-dependent glutamate synthase activity" EXACT [GO:0016040] synonym: "abolished NADH: GOGAT activity" RELATED [GO:0016040] synonym: "glutamate synthase (NADH) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0005470 ! abnormal glutamate synthase (NADH) activity created_by: midori creation_date: 2016-07-04T13:48:22Z [Term] id: FYPO:0005472 name: abolished glutamate dehydrogenase (NADP+) activity def: "A molecular function phenotype in which glutamate dehydrogenase activity using NAPD+ as a cofactor is absent." [PomBase:mah] synonym: "abolished NAD(P)H-dependent glutamate dehydrogenase activity" EXACT [GO:0004354] synonym: "abolished NADP-GDH activity" EXACT [PMID:7773104, PomBase:vw] synonym: "glutamate dehydrogenase (NADP+) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000982 ! abnormal glutamate dehydrogenase (NADP+) activity created_by: midori creation_date: 2016-07-04T13:56:27Z [Term] id: FYPO:0005473 name: normal glutamate synthase (NADH) activity def: "A molecular function phenotype in which the observed rate of glutamate synthase activity using NADH as a cofactor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glutamate (reduced nicotinamide adenine dinucleotide) synthase" EXACT [GO:0016040] synonym: "normal L-glutamate synthase (NADH) activity" EXACT [GO:0016040] synonym: "normal NADH-dependent glutamate synthase activity" EXACT [GO:0016040] synonym: "normal NADH: GOGAT activity" RELATED [GO:0016040] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2016-07-04T14:01:39Z [Term] id: FYPO:0005474 name: normal glutamate dehydrogenase (NADP+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal NAD(P)H-dependent glutamate dehydrogenase activity" EXACT [GO:0004354] synonym: "normal NADP-GDH activity" EXACT [PMID:7773104, PomBase:vw] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2016-07-04T14:04:39Z [Term] id: FYPO:0005475 name: swollen vegetative cell with normal cell length def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is normal length but has a larger volume than normal." [PMID:9459302, PomBase:mah] synonym: "normal length cell with increased cell volume" EXACT [PomBase:mah] synonym: "swollen cell with normal cell length during vegetative growth" EXACT [PomBase:mah] synonym: "swollen vegetative cell with normal cell length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "swollen, normal length vegetative cell" EXACT [PomBase:vw] is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0003503 ! normal vegetative cell length relationship: has_part FYPO:0000646 ! swollen vegetative cell relationship: has_part FYPO:0003503 ! normal vegetative cell length created_by: midori creation_date: 2016-07-04T14:30:38Z [Term] id: FYPO:0005476 name: decreased filamentous actin level def: "A cell phenotype in which the amount of filamentous actin measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. The total actin level (globular and filamentous actin) may be normal or abnormal." [PomBase:mah] synonym: "decreased accumulation of filamentous actin in cell" RELATED [PomBase:mah] synonym: "decreased cellular F-actin level" EXACT [PomBase:mah] synonym: "decreased cellular filamentous actin level" EXACT [PomBase:mah] synonym: "decreased filamentous actin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased filamentous actin level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced filamentous actin level" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2016-07-04T14:42:55Z [Term] id: FYPO:0005477 name: normal protein phosphorylation during cellular response to arsenite ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to arsenite ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to arsenite" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to arsenite ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to arsenite ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-07-04T14:47:59Z [Term] id: FYPO:0005478 name: abolished protein phosphorylation during cellular response to arsenite ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to arsenite ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to arsenite" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to arsenite ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to arsenite ion during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to arsenite ion" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-07-04T14:50:11Z [Term] id: FYPO:0005479 name: decreased protein phosphorylation during cellular response to arsenite ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to arsenite ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to arsenite" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to arsenite ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to arsenite ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to arsenite ion" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-07-04T14:53:12Z [Term] id: FYPO:0005480 name: increased protein phosphorylation during cellular response to arsenite ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to arsenite ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to arsenite" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to arsenite ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to arsenite ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001265 ! increased protein phosphorylation during cellular hyperosmotic response created_by: midori creation_date: 2016-07-04T14:54:10Z [Term] id: FYPO:0005481 name: normal diphosphoinositol-pentakisphosphate kinase activity def: "A molecular function phenotype in which the observed rate of an diphosphoinositol-pentakisphosphate kinase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal PP-InsP5 kinase activity" EXACT [GO:0033857] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2016-07-04T15:02:40Z [Term] id: FYPO:0005482 name: abnormal inositol phosphate phosphatase activity def: "A molecular function phenotype in which the observed rate of an inositol phosphate phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-07-04T15:04:29Z [Term] id: FYPO:0005483 name: increased inositol phosphate phosphatase activity def: "A molecular function phenotype in which the observed rate of an inositol phosphate phosphatase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0005482 ! abnormal inositol phosphate phosphatase activity created_by: midori creation_date: 2016-07-04T15:04:37Z [Term] id: FYPO:0005484 name: decreased inositol phosphate phosphatase activity def: "A molecular function phenotype in which the observed rate of an inositol phosphate phosphatase activity is decreased." [PomBase:mah] synonym: "reduced inositol phosphate phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005482 ! abnormal inositol phosphate phosphatase activity created_by: midori creation_date: 2016-07-04T15:04:37Z [Term] id: FYPO:0005485 name: abolished inositol phosphate phosphatase activity def: "A molecular function phenotype in which an inositol phosphate phosphatase activity is absent." [PomBase:mah] synonym: "inositol phosphate phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0005482 ! abnormal inositol phosphate phosphatase activity created_by: midori creation_date: 2016-07-04T15:04:37Z [Term] id: FYPO:0005486 name: increased iron-sulfur cluster binding def: "A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds an iron-sulfur cluster more than wild type, or that a mutation in one gene increases iron-sulfur cluster binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "increased iron-sulphur cluster binding" EXACT [PomBase:mah] is_a: FYPO:0001709 ! abnormal iron-sulfur cluster binding created_by: midori creation_date: 2016-07-04T15:53:25Z [Term] id: FYPO:0005487 name: decreased iron-sulfur cluster binding def: "A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds an iron-sulfur cluster less than wild type, or that a mutation in one gene decreases iron-sulfur cluster binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "decreased iron-sulphur cluster binding" EXACT [PomBase:mah] synonym: "reduced iron-sulfur cluster binding" EXACT [PomBase:mah] is_a: FYPO:0001709 ! abnormal iron-sulfur cluster binding created_by: midori creation_date: 2016-07-04T15:53:25Z [Term] id: FYPO:0005488 name: sensitive to arsenite def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to arsenite ions. Cells stop growing (and may die) at a concentration of arsenite that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to arsenite" EXACT [PomBase:mah] synonym: "sensitive to arsenite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to arsenite during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to arsenite ions" EXACT [PomBase:mah] is_a: FYPO:0000093 ! sensitive to arsenic created_by: midori creation_date: 2016-07-06T13:52:34Z [Term] id: FYPO:0005489 name: protein mislocalized to vacuolar membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the vacuolar membrane is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the mitochondrion in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to vacuolar membrane" EXACT [PomBase:vw] synonym: "protein mislocalised to vacuolar membrane" EXACT [PomBase:mah] synonym: "protein mislocalised to vacuolar membrane during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to vacuolar membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to vacuolar membrane during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to vacuole membrane" EXACT [PomBase:mah] is_a: FYPO:0005514 ! protein mislocalized to vacuole created_by: midori creation_date: 2016-07-06T14:00:23Z [Term] id: FYPO:0005490 name: abnormal protein localization to vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuole is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to vacuole" EXACT [PomBase:mah] synonym: "abnormal protein localization in vacuole" EXACT [PomBase:mah] synonym: "abnormal protein localization to vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to vacuole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2016-07-06T14:01:54Z [Term] id: FYPO:0005491 name: decreased maintenance of protein localization in vacuole, with protein secreted def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of protein localization in vacuole occurs to a lower extent than normal, and some of the protein is secreted, i.e. some of a protein that normally resides in the vacuole is instead secreted." [PMID:22484924, PomBase:mah] comment: The difference between this term and 'decreased protein targeting to vacuole, with protein secreted' (FYPO:0005547) is that this term refers to proteins remaining in the vacuole after they are targeted there, whereas FYPO:0005547 refers to the initial targeting of proteins to the vacuole. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased maintenance of protein localisation in vacuole, with protein secreted" EXACT [PomBase:mah] synonym: "decreased maintenance of protein localization in vacuole, with protein secreted, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased maintenance of protein localization in vacuole, with protein secreted, during vegetative growth" EXACT [PomBase:mah] synonym: "protein partially mislocalized from vacuole to extracellular region" RELATED [PomBase:vw] synonym: "reduced maintenance of protein localization in vacuole, with protein secreted" EXACT [PomBase:mah] is_a: FYPO:0005490 ! abnormal protein localization to vacuole created_by: midori creation_date: 2016-07-06T14:03:13Z [Term] id: FYPO:0005492 name: abolished maintenance of protein localization in vacuole, with protein secreted def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of protein localization in vacuole does not occur, and some of the protein is secreted, i.e. a protein that normally resides in the vacuole is instead secreted." [PMID:22484924, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished maintenance of protein localisation in vacuole, with protein secreted" EXACT [PomBase:mah] synonym: "abolished maintenance of protein localization in vacuole, with protein secreted, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished maintenance of protein localization in vacuole, with protein secreted, during vegetative growth" EXACT [PomBase:mah] synonym: "maintenance of protein localization in vacuole abolished, with protein secreted" EXACT [PomBase:mah] synonym: "protein mislocalized from vacuole to extracellular region" RELATED [PomBase:vw] is_a: FYPO:0005490 ! abnormal protein localization to vacuole created_by: midori creation_date: 2016-07-06T14:07:30Z [Term] id: FYPO:0005493 name: normal endosome to Golgi transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins or other substances from the endosome to the Golgi is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) from the endosome to the Golgi. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "normal endosome to Golgi protein transport" NARROW [PomBase:mah] synonym: "normal endosome to Golgi transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal endosome to Golgi transport during vegetative growth" EXACT [PomBase:mah] synonym: "normal retrograde transport, endosome to Golgi" EXACT [GO:0042147] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2016-07-06T14:09:13Z [Term] id: FYPO:0005494 name: decreased protein transport along microtubule during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins along microtubules is decreased. Transport of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay. synonym: "decreased protein movement along microtubule during vegetative growth" EXACT [PomBase:vw] synonym: "decreased protein transport along microtubule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein transport along microtubule during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005830 ! abnormal protein transport along microtubule during vegetative growth created_by: midori creation_date: 2016-07-06T14:34:45Z [Term] id: FYPO:0005495 name: increased transcription from CRE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a greater extent than normal." [PMID:26108447, PomBase:mah] synonym: "expression of CRE target genes increased" RELATED [PomBase:mah] synonym: "increased transcription from CRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from CRE promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2016-07-06T14:41:43Z [Term] id: FYPO:0005496 name: decreased transcription from CRE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a lower extent than normal." [PMID:26108447, PomBase:mah] synonym: "decreased transcription from CRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from CRE promoter during vegetative growth" EXACT [PomBase:mah] synonym: "expression of CRE target genes decreased" RELATED [PomBase:mah] synonym: "reduced transcription from CRE promoter" EXACT [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2016-07-06T14:43:10Z [Term] id: FYPO:0005497 name: abolished transcription from CRE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements does not occur." [PMID:26108447, PomBase:mah] synonym: "abolished transcription from CRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished transcription from CRE promoter during vegetative growth" EXACT [PomBase:mah] synonym: "expression of CRE target genes abolished" RELATED [PomBase:mah] synonym: "transcription from CRE promoter abolished" EXACT [PomBase:mah] is_a: FYPO:0003796 ! abolished transcription from RNA polymerase II promoter is_a: FYPO:0005496 ! decreased transcription from CRE promoter created_by: midori creation_date: 2016-07-06T14:44:41Z [Term] id: FYPO:0005498 name: increased transcription from CRE promoter during cellular response to miconazole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a greater extent than normal during a cellular response to miconazole." [PomBase:mah] synonym: "expression of CRE target genes increased during cellular response to miconazole" RELATED [PomBase:mah] synonym: "increased transcription from CRE promoter during cellular response to miconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from CRE promoter during cellular response to miconazole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005495 ! increased transcription from CRE promoter created_by: midori creation_date: 2016-07-06T14:45:44Z [Term] id: FYPO:0005499 name: decreased transcription from CRE promoter during cellular response to miconazole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a lower extent than normal during a cellular response to miconazole." [PomBase:mah] synonym: "decreased transcription from CRE promoter during cellular response to miconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from CRE promoter during cellular response to miconazole during vegetative growth" EXACT [PomBase:mah] synonym: "expression of CRE target genes decreased during cellular response to miconazole" RELATED [PomBase:mah] is_a: FYPO:0005496 ! decreased transcription from CRE promoter created_by: midori creation_date: 2016-07-06T14:47:44Z [Term] id: FYPO:0005500 name: abolished transcription from CRE promoter during cellular response to miconazole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements does not occur during a cellular response to miconazole." [PMID:26108447, PomBase:mah] synonym: "abolished transcription from CRE promoter during cellular response to miconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished transcription from CRE promoter during cellular response to miconazole during vegetative growth" EXACT [PomBase:mah] synonym: "expression of CRE target genes abolished during cellular response to miconazole" RELATED [PomBase:mah] synonym: "transcription from CRE promoter abolished during cellular response to miconazole" EXACT [PomBase:mah] is_a: FYPO:0005497 ! abolished transcription from CRE promoter created_by: midori creation_date: 2016-07-06T14:49:02Z [Term] id: FYPO:0005501 name: abolished protein localization to cell cortex, with protein mislocalized to cytoplasm, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell cortex, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell cortex, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to cell cortex abolished, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized from cortical regions to cytoplasm during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0000930 ! abolished protein localization to cell cortex during vegetative growth relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2016-07-06T15:36:26Z [Term] id: FYPO:0005502 name: abnormal transcription def: "A cellular process phenotype in which transcription is abnormal in extent, timing, start or termination site, etc. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "abnormal transcription, DNA-dependent" EXACT [GO:0006351] is_a: FYPO:0004847 ! transcription phenotype is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2016-07-06T15:42:16Z [Term] id: FYPO:0005503 name: abnormally monopolar protein localization to cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized to both cell tips is instead found at only one tip." [PMID:26749213, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal monopolar protein localization to one cell end" EXACT [PomBase:vw] synonym: "abnormally monopolar protein localisation to cell tip" EXACT [PomBase:mah] synonym: "abnormally monopolar protein localization to cell end" EXACT [PomBase:mah] synonym: "abnormally monopolar protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormally monopolar protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2016-07-13T12:13:51Z [Term] id: FYPO:0005504 name: abolished galactose-specific flocculation def: "A phenotype in which galactose-specific flocculation does not occur. Galactose-specific flocculation is the non-sexual aggregation of single cells, mediated by the binding of cell wall proteins on one cell to galactose residues on the other." [GO:0036349, PMID:23236291, PomBase:mah] synonym: "abolished flocculation" BROAD [PomBase:mah] synonym: "galactose-specific flocculation abolished" EXACT [PomBase:mah] is_a: FYPO:0005448 ! abolished biological process created_by: midori creation_date: 2016-07-13T12:37:20Z [Term] id: FYPO:0005505 name: increased level of cell surface glycoprotein gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell surface glycoprotein mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Cell surface glycoprotein gene mRNAs encode proteins that become glycosylated and are transported to the cell surface." [PMID:23236291, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased cell surface glycoprotein gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of cell surface glycoprotein gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of cell surface glycoprotein gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of cell surface glycoprotein gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2016-07-13T12:42:54Z [Term] id: FYPO:0005506 name: increased level of mitochondrial transport gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more mitochondrial transport mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Mitochondrial transport mRNAs are transcribed from genes whose products are involved in transport to or from the mitochondrion." [PMID:23236291, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of mitochondrial transport gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of mitochondrial transport gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of mitochondrial transport gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased mitochondrial transport gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0004490 ! increased level of transport gene mRNA during vegetative growth created_by: midori creation_date: 2016-07-13T12:45:15Z [Term] id: FYPO:0005507 name: increased mature rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature ribosomal RNA (rRNA) measured in a cell is higher than normal. Total rRNA or a specific rRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mature ribosomal RNA level" EXACT [PomBase:mah] synonym: "increased mature rRNA accumulation" RELATED [PomBase:mah] synonym: "increased mature rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature rRNA transcript level" BROAD [PomBase:vw] synonym: "increased rRNA level" BROAD [PomBase:mah] is_a: FYPO:0006468 ! altered mature rRNA level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2016-07-13T12:48:05Z [Term] id: FYPO:0005508 name: abnormal plasma membrane to vacuole transport def: "A cellular process phenotype in which the transport of a substance from the plasma membrane to the vacuole is abnormal. Transport normally occurs in two stages, plasma membrane to endosome followed by endosome to vacuole transport." [PMID:26749213, PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) from the plasma membrane to the vacuole. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "abnormal plasma membrane to vacuole protein transport" NARROW [PomBase:mah] is_a: FYPO:0000597 ! abnormal vacuolar transport during vegetative growth created_by: midori creation_date: 2016-07-13T12:58:29Z [Term] id: FYPO:0005509 name: abnormal meiotic sister chromatid segregation def: "A cellular process phenotype in which meiotic sister chromatid segregation is abnormal. Meiotic sister chromatid segregation is the process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GO:0045144, PomBase:mah] synonym: "abnormal sister chromatid segregation during meiosis II" EXACT [PomBase:mah] synonym: "chromosome missegregation during meiosis II" RELATED [PomBase:vw] synonym: "meiotic chromosome missegregation" RELATED [PomBase:vw] synonym: "meiotic sister chromatid missegregation" RELATED [PomBase:vw] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2016-07-13T12:59:55Z [Term] id: FYPO:0005510 name: meiosis II metaphase/anaphase transition delay def: "A cell cycle phenotype in which the onset of anaphase of the second meiotic nuclear division begins later than normal." [PomBase:mah] synonym: "delayed cell cycle passage through meiosis II metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "delayed metaphase/anaphase transition of meiosis II" EXACT [GO:1990950] synonym: "delayed onset of meiotic anaphase II" EXACT [PomBase:vw] synonym: "increased duration of meiosis II metaphase" RELATED [PomBase:mah] synonym: "increased duration of metaphase during meiosis II" RELATED [PomBase:mah] synonym: "meiotic cell cycle delay at second metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "metaphase/anaphase transition delay during meiosis II" EXACT [PomBase:mah] synonym: "metaphase/anaphase transition delay during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0005274 ! abnormal meiotic cell cycle phase transition created_by: midori creation_date: 2016-07-13T13:47:46Z [Term] id: FYPO:0005511 name: meiotic cell cycle checkpoint phenotype def: "A cell phenotype that affects any meiotic cell cycle checkpoint." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast meiotic cell cycle checkpoint phenotype" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000631 ! cell cycle phenotype created_by: midori creation_date: 2016-07-13T13:50:14Z [Term] id: FYPO:0005512 name: increased activation of meiosis I spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the meiosis I spindle assembly checkpoint is activated more frequently than normal, typically under conditions that do not cause checkpoint activation in wild-type cells. The meiosis I spindle assembly checkpoint normally delays the metaphase/anaphase transition of the first meiotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PMID:26483559, PomBase:mah, PomBase:vw] comment: Checkpoint activation in a mutant usually implies that the mutation is causing problems that the checkpoint detects. synonym: "increased activation of first meiotic nuclear division spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "increased activation of meiosis I cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "increased activation of spindle assembly checkpoint during meiosis I" EXACT [PomBase:mah] synonym: "increased meiosis I spindle assembly checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0005511 ! meiotic cell cycle checkpoint phenotype created_by: midori creation_date: 2016-07-13T13:50:44Z [Term] id: FYPO:0005513 name: increased protein localization to kinetochore during meiosis def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is increased during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to kinetochore during meiosis" EXACT [PomBase:mah] synonym: "increased protein localization to kinetochore during meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased protein localization to meiotic kinetochore" EXACT [PomBase:vw] is_a: FYPO:0004762 ! abnormal protein localization to kinetochore during meiosis is_a: FYPO:0005598 ! increased protein localization to centromere during meiotic cell cycle created_by: midori creation_date: 2016-07-13T14:29:49Z [Term] id: FYPO:0005514 name: protein mislocalized to vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the vacuole is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the vacuole in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to vacuole" EXACT [PomBase:vw] synonym: "protein mislocalised to vacuole" EXACT [PomBase:mah] synonym: "protein mislocalised to vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to vacuole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2016-07-13T14:46:31Z [Term] id: FYPO:0005515 name: abolished protein localization to cell cortex, with protein mislocalized to vacuole, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abolished, and the protein is present in the vacuole instead." [PMID:26749213, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell cortex, with protein mislocalised to vacuole, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell cortex, with protein mislocalized to vacuole, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to cell cortex abolished, with protein mislocalized to vacuole, during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized from cortical regions to vacuole during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalized to vacuoles from cortical region during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0005501 ! abolished protein localization to cell cortex, with protein mislocalized to cytoplasm, during vegetative growth is_a: FYPO:0005514 ! protein mislocalized to vacuole relationship: has_part FYPO:0005514 ! protein mislocalized to vacuole created_by: midori creation_date: 2016-07-13T14:52:16Z [Term] id: FYPO:0005516 name: decreased nucleosome occupancy in euchromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in regions of euchromatin. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:22990236, PomBase:mah] synonym: "decreased nucleosome occupancy in euchromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy in euchromatin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy in euchromatin" EXACT [PomBase:mah] is_a: FYPO:0000854 ! abnormal nucleosome positioning in euchromatin is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: midori creation_date: 2016-07-13T14:58:34Z [Term] id: FYPO:0005517 name: normal growth on 6-azauracil def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 6-azauracil." [PomBase:mah] synonym: "normal cell population growth in presence of 6-azauracil" EXACT [PomBase:mah] synonym: "normal cell population growth on 6-azauracil" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to 6-azauracil" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on 6-azauracil" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2016-07-13T15:05:14Z [Term] id: FYPO:0005518 name: increased histone H3-K14 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in regions containing protein coding genes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2016-07-13T15:09:36Z [Term] id: FYPO:0005519 name: abnormal nucleosome-dependent ATPase activity def: "A molecular function phenotype in which the observed rate of nucleosome-dependent ATPase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-07-13T15:11:50Z [Term] id: FYPO:0005520 name: abolished nucleosome-dependent ATPase activity def: "A molecular function phenotype in which nucleosome-dependent ATPase activity is absent." [PomBase:mah] synonym: "nucleosome-dependent ATPase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0005519 ! abnormal nucleosome-dependent ATPase activity created_by: midori creation_date: 2016-07-13T15:11:57Z [Term] id: FYPO:0005521 name: abnormal nucleosome organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome organization is abnormal. Nucleosome organization results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes." [GO:0034728, PomBase:mah] synonym: "abnormal nucleosome organisation" EXACT [PomBase:mah] synonym: "abnormal nucleosome organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleosome organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2016-07-13T15:14:34Z [Term] id: FYPO:0005522 name: increased forward centromeric outer repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed in the forward direction from the centromere outer repeat region are present at greater levels than normal." [PMID:22990236, PomBase:mah] comment: This term encompasses both unprocessed RNA transcribed from the centromere outer repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'decreased chromatin silencing at centromere outer repeat region' (FYPO:0003412). synonym: "increased accumulation of forward centromeric outer repeat transcripts" RELATED [PomBase:mah] synonym: "increased accumulation of forward centromeric outer repeat transcripts during vegetative growth" RELATED [PomBase:mah] synonym: "increased accumulation of forward non-coding outer repeat transcripts" EXACT [PomBase:vw] synonym: "increased forward centromere outer repeat transcript level" EXACT [PomBase:mah] synonym: "increased forward centromeric outer repeat transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased forward centromeric outer repeat transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "increased forward centromeric outer repeat-derived transcript level" EXACT [PomBase:vw] synonym: "increased level of forward centromeric outer repeat transcripts" EXACT [PomBase:mah] is_a: FYPO:0000220 ! increased centromeric outer repeat transcript level created_by: midori creation_date: 2016-07-13T15:25:54Z [Term] id: FYPO:0005523 name: increased reverse centromeric outer repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed in the reverse direction from the centromere outer repeat region are present at greater levels than normal." [PMID:22990236, PomBase:mah] comment: This term encompasses both unprocessed RNA transcribed from the centromere outer repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere outer repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the outer repeat region, consider 'decreased chromatin silencing at centromere outer repeat region' (FYPO:0003412). synonym: "increased accumulation of reverse centromeric outer repeat transcripts" RELATED [PomBase:mah] synonym: "increased accumulation of reverse centromeric outer repeat transcripts during vegetative growth" RELATED [PomBase:mah] synonym: "increased accumulation of reverse non-coding outer repeat transcripts" EXACT [PomBase:vw] synonym: "increased level of reverse centromeric outer repeat transcripts" EXACT [PomBase:mah] synonym: "increased reverse centromere outer repeat transcript level" EXACT [PomBase:mah] synonym: "increased reverse centromeric outer repeat transcript level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased reverse centromeric outer repeat transcript level during vegetative growth" EXACT [PomBase:mah] synonym: "increased reverse centromeric outer repeat-derived transcript level" EXACT [PomBase:vw] is_a: FYPO:0000220 ! increased centromeric outer repeat transcript level created_by: midori creation_date: 2016-07-13T15:27:35Z [Term] id: FYPO:0005524 name: decreased nucleosome occupancy at centromere central core def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in the central core of the centromeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:22990236, PomBase:mah] synonym: "decreased nucleosome occupancy at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy in centromere central core" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at centromere central core" EXACT [PomBase:mah] is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: midori creation_date: 2016-07-13T15:28:44Z [Term] id: FYPO:0005525 name: decreased nucleosome occupancy at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in centromere inner repeat regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:22990236, PomBase:mah] synonym: "decreased nucleosome occupancy at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy in centromere inner repeat" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0008151 ! decreased nucleosome occupancy at centromeric heterochromatin created_by: midori creation_date: 2016-07-13T15:32:28Z [Term] id: FYPO:0005526 name: decreased transport along microtubule during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of organelles or other particles along microtubules is decreased." [PomBase:mah] synonym: "decreased establishment of localization by movement along microtubule during vegetative growth" EXACT [GO:0010970] synonym: "decreased microtubule-based transport during vegetative growth" BROAD [GO:0010970] synonym: "decreased movement along microtubule during vegetative growth" EXACT [GO:0010970] synonym: "decreased transport along microtubule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced transport along microtubule during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2016-07-13T15:35:24Z [Term] id: FYPO:0005527 name: normal subtelomeric chromatin knob formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin knobs in subtelomeric regions is normal (i.e. indistinguishable from wild type). Chromatin knobs are highly condensed chromatin bodies formed from subtelomeric heterochromatin (observed on chromosomes 1 and 2)." [PMID:26205977, PomBase:mah] synonym: "normal frequency of knob-containing nuclei" RELATED [Pombase:al] synonym: "normal subtelomeric chromatin condensation" BROAD [PomBase:mah] synonym: "normal subtelomeric chromatin knob assembly" EXACT [PomBase:mah] is_a: FYPO:0002891 ! normal chromatin organization during vegetative growth created_by: midori creation_date: 2016-07-19T12:50:59Z [Term] id: FYPO:0005528 name: decreased subtelomeric chromatin knob formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin knobs in subtelomeric regions is decreased. Chromatin knobs are highly condensed chromatin bodies formed from subtelomeric heterochromatin (observed on chromosomes 1 and 2)." [PMID:26205977, PomBase:mah] synonym: "decreased frequency of knob-containing nuclei" RELATED [Pombase:al] synonym: "decreased subtelomeric chromatin condensation" BROAD [PomBase:mah] synonym: "decreased subtelomeric chromatin knob assembly" EXACT [PomBase:mah] synonym: "reduced subtelomeric chromatin knob formation" EXACT [PomBase:mah] is_a: FYPO:0004543 ! abnormal heterochromatin organization during vegetative growth created_by: midori creation_date: 2016-07-19T12:54:47Z [Term] id: FYPO:0005529 name: normal protein localization to chromatin at boundary element IRC1L def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is normal (i.e. indistinguishable from wild type)." [PMID:25972440, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at boundary element IRC1L" EXACT [PomBase:mah] synonym: "normal protein localization to centromeric boundary element IRC1L" EXACT [PomBase:al] synonym: "normal protein localization to chromatin at boundary element IRC1L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at boundary element IRC1L during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-07-19T15:08:57Z [Term] id: FYPO:0005530 name: abolished protein localization to chromatin at boundary element IRC1L def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is abolished." [PMID:25972440, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at boundary element IRC1L during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to centromeric boundary element IRC1L" EXACT [PomBase:al] synonym: "abolished protein localization to chromatin at boundary element IRC1L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to chromatin at boundary element IRC1L during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-07-19T15:11:07Z [Term] id: FYPO:0005531 name: decreased protein localization to chromatin at boundary element IRC1L def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is decreased." [PMID:25972440, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at boundary element IRC1L" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric boundary element IRC1L" EXACT [PomBase:al] synonym: "decreased protein localization to chromatin at boundary element IRC1L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at boundary element IRC1L during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at boundary element IRC1L" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2016-07-19T15:12:23Z [Term] id: FYPO:0005532 name: abnormal histone H4-K16 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 is abnormal." [PomBase:mah] synonym: "abnormal histone H4-K16 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal histone H4K16 acetylation during vegetative growth" EXACT [GO:0043984, PomBase:vw] is_a: FYPO:0002364 ! abnormal histone H4 acetylation during vegetative growth created_by: midori creation_date: 2016-07-19T15:15:26Z [Term] id: FYPO:0005533 name: decreased histone H4-K16 acetylation at boundary element IRC1L during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 at the IRC1L boundary element occurs to a lower extent than normal." [PMID:25972440, PomBase:mah] synonym: "decreased histone H4-K16 acetylation at boundary element IRC1L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4K16 acetylation at centromeric boundary element IRC1L during vegetative growth" EXACT [PomBase:al] synonym: "reduced histone H4-K16 acetylation at boundary element IRC1L during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0005532 ! abnormal histone H4-K16 acetylation during vegetative growth created_by: midori creation_date: 2016-07-19T15:16:53Z [Term] id: FYPO:0005534 name: decreased histone H4-K16 acetylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in telomeric regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H4-K16 acetylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone H4-K16 acetylation at telomere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation during vegetative growth is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth is_a: FYPO:0005011 ! decreased histone H4 acetylation during vegetative growth created_by: midori creation_date: 2016-07-19T15:29:50Z [Term] id: FYPO:0005535 name: increased histone H4-K16 acetylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in telomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K16 acetylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0007632 ! increased histone H4-K16 acetylation during vegetative growth created_by: midori creation_date: 2016-07-19T15:30:07Z [Term] id: FYPO:0005536 name: normal RNA localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of an RNA to the nucleus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal RNA localisation to nucleus" EXACT [PomBase:mah] synonym: "normal RNA localization to nucleus during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal RNA localization to nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0003058 ! normal RNA localization created_by: midori creation_date: 2016-07-19T15:38:18Z [Term] id: FYPO:0005537 name: normal telomerase holoenzyme complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomerase holoenzyme complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal telomerase holoenzyme complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal telomerase holoenzyme complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2016-07-19T15:41:52Z [Term] id: FYPO:0005538 name: normal telomere-telomerase complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere-telomerase complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal telomere-telomerase complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal telomere-telomerase complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2016-07-19T15:43:09Z [Term] id: FYPO:0005539 name: abnormal telomerase RNA reverse transcriptase activity def: "A molecular function phenotype in which the observed rate of telomerase RNA reverse transcriptase activity is abnormal." [PomBase:mah] synonym: "abnormal telomerase activity" BROAD [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-07-19T15:44:34Z [Term] id: FYPO:0005540 name: decreased telomerase RNA reverse transcriptase activity def: "A molecular function phenotype in which the observed rate of telomerase RNA reverse transcriptase activity is decreased." [PomBase:mah] synonym: "decreased telomerase activity" BROAD [PomBase:mah] synonym: "reduced telomerase RNA reverse transcriptase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005539 ! abnormal telomerase RNA reverse transcriptase activity created_by: midori creation_date: 2016-07-19T15:44:41Z [Term] id: FYPO:0005541 name: normal DNA recombination frequency at subtelomeric heterochromatin def: "A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) in subtelomeric regions." [PomBase:mah] synonym: "normal DNA recombination frequency at subtelomere" EXACT [PomBase:mah] synonym: "normal DNA recombination frequency at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA recombination frequency at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-07-19T15:47:02Z [Term] id: FYPO:0005542 name: abnormal telomerase template activity def: "A molecular function phenotype in which telomerase template activity is abnormal." [PomBase:mah] synonym: "abnormal telomerase RNA activity" EXACT [GO:0000332] synonym: "abnormal template for synthesis of G-rich strand of telomere DNA activity" EXACT [GO:0000332] is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2016-07-19T15:50:16Z [Term] id: FYPO:0005543 name: increased duration of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of actomyosin contractile ring contraction is longer than normal." [PomBase:mah] synonym: "increased duration of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "prolonged actomyosin contractile ring contraction" EXACT [PomBase:mah] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2016-07-19T15:59:36Z [Term] id: FYPO:0005544 name: abnormal protein localization to plasma membrane at cell division site during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abnormal." [PMID:27082518, PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell division site plasma membrane and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to plasma membrane at cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization in plasma membrane at cell division site during vegetative growth" EXACT [GO:0072659] synonym: "abnormal protein localization to cell division site plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to plasma membrane at cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to plasma membrane division site during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0002125 ! abnormal protein localization to plasma membrane during vegetative growth created_by: midori creation_date: 2016-07-19T16:03:46Z [Term] id: FYPO:0005545 name: decreased Tf body formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such that regions containing transposons (Tf2 elements) are physically clustered to a lower extent than normal." [PMID:27343236, PomBase:mah] synonym: "decreased clustering of Tf2 bodies" EXACT [PomBase:al] synonym: "decreased Tf body formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Tf body formation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Tf clustering" EXACT [PomBase:mah] synonym: "decreased Tf2 body formation" EXACT [PomBase:vw] synonym: "reduced Tf body formation" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2016-07-19T16:11:41Z [Term] id: FYPO:0005546 name: decreased protein-protein interaction during mitotic S phase def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during S phase of the mitotic cell cycle. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding during mitotic S phase" EXACT [PomBase:mah] synonym: "reduced protein-protein interaction during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction created_by: midori creation_date: 2016-07-19T16:15:42Z [Term] id: FYPO:0005547 name: decreased protein targeting to vacuole, with protein secreted def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole occurs to a lower extent than normal, and some of the protein is secreted." [PMID:22484924, PomBase:mah] comment: The difference between this term and 'decreased maintenance of protein localization in vacuole, with protein secreted' (FYPO:0005491) is that this term refers to the initial targeting of proteins to the vacuole, whereas FYPO:0005491 refers to proteins remaining in the vacuole after they are targeted there. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein targeting to vacuole, with protein secreted, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein targeting to vacuole, with protein secreted, during vegetative growth" EXACT [PomBase:mah] synonym: "protein partially mislocalized from vacuole to extracellular region" RELATED [PomBase:vw] synonym: "reduced protein targeting to vacuole, with protein secreted" EXACT [PomBase:mah] is_a: FYPO:0000676 ! abnormal protein targeting to vacuole created_by: midori creation_date: 2016-08-01T13:42:06Z [Term] id: FYPO:0005548 name: increased protein phosphorylation during cellular response to brefeldin A def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to brefeldin A." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to brefeldin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to brefeldin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-08-01T13:58:09Z [Term] id: FYPO:0005549 name: normal viability upon nitrogen starvation def: "A cell population phenotype in which a normal proportion of cells in the population remains viable when cells in a culture are deprived of nitrogen." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase under nitrogen-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "normal cell population viability upon nitrogen starvation" EXACT [PomBase:mah] synonym: "normal viability in stationary phase upon nitrogen depletion" RELATED [PomBase:mah] synonym: "normal viability upon nitrogen depletion" EXACT [PomBase:al] synonym: "normal viability upon nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2016-08-01T14:00:03Z [Term] id: FYPO:0005550 name: normal protein level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydroxyurea is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to HU" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2016-08-01T14:06:13Z [Term] id: FYPO:0005551 name: decreased protein localization to cleavage furrow def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cleavage furrow is decreased." [PMID:27082518, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cleavage furrow" EXACT [PomBase:mah] synonym: "decreased protein localization to cleavage furrow during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cleavage furrow during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cleavage furrow" EXACT [PomBase:mah] is_a: FYPO:0002869 ! decreased protein localization to cell division site created_by: midori creation_date: 2016-08-01T14:24:32Z [Term] id: FYPO:0005552 name: decreased protein localization to cleavage furrow rim def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cleavage furrow rim is decreased. The rim is the part of the cleavage furrow closest to the contractile ring." [PMID:27082518, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cleavage furrow rim" EXACT [PomBase:mah] synonym: "decreased protein localization to cleavage furrow rim during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cleavage furrow rim during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cleavage furrow rim" EXACT [PomBase:mah] is_a: FYPO:0005551 ! decreased protein localization to cleavage furrow created_by: midori creation_date: 2016-08-01T14:25:58Z [Term] id: FYPO:0005553 name: normal single-stranded telomeric DNA binding def: "A molecular function phenotype in which occurrence of single-stranded telomeric DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal ssDNA telomeric binding" EXACT [GO:0043047] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2016-08-01T14:51:23Z [Term] id: FYPO:0005554 name: abolished histone H3-K9 dimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere CENP-A containing region during vegetative growth" RELATED [PomBase:vw] synonym: "abolished histone H3-K9 dimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me2 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent at centromere inner repeat during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0004170 ! abolished histone H3-K9 dimethylation at centromere during vegetative growth created_by: midori creation_date: 2016-08-01T14:53:13Z [Term] id: FYPO:0005555 name: decreased mitotic cohesin loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin loading is decreased during the mitotic cell cycle. Cohesin loading is the topological linking of a cohesin ring complex to chromatin." [GO:0061780, PomBase:mah] synonym: "decreased cohesin loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased cohesin loading during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic cohesin association with chromatin" EXACT [GO:0071921] synonym: "decreased mitotic cohesin localization to chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "reduced mitotic cohesin loading" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0000682 ! abnormal regulation of molecular function is_a: FYPO:0006479 ! abnormal cohesin loading created_by: midori creation_date: 2016-08-02T12:11:20Z [Term] id: FYPO:0005556 name: abolished mitotic cohesin loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin loading does not occur during the mitotic cell cycle. Cohesin loading is the topological linking of a cohesin ring complex to chromatin." [GO:0061780, PomBase:mah] synonym: "abolished cohesin loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished cohesin loading during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic cohesin association with chromatin" EXACT [GO:0071921] synonym: "abolished mitotic cohesin localization to chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "mitotic cohesin loading abolished" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0000682 ! abnormal regulation of molecular function is_a: FYPO:0006479 ! abnormal cohesin loading created_by: midori creation_date: 2016-08-02T12:14:09Z [Term] id: FYPO:0005557 name: decreased mitotic cohesin unloading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin unloading is decreased during the mitotic cell cycle. Cohesin unloading is the topological unlinking of a cohesin ring complex from chromatin, which negatively regulates sister chromatid cohesion." [GO:0061781, PomBase:mah] synonym: "decreased cohesin unloading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased cohesin unloading during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cohesin unloading" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-08-02T12:15:17Z [Term] id: FYPO:0005558 name: abnormal microtubule bundle alt_id: FYPO:0005795 def: "A physical cellular phenotype in which the amount, distribution, or morphology of microtubule bundles is abnormal." [PomBase:mah] synonym: "abnormal microtubule array" RELATED [PomBase:vw] synonym: "abnormal microtubule bundle physical object quality" EXACT [PomBase:mah] synonym: "abnormal microtubule bundle structure" NARROW [] synonym: "abnormal MT bundle" EXACT [PomBase:mah] is_a: FYPO:0002399 ! abnormal microtubule cytoskeleton created_by: midori creation_date: 2016-08-02T12:21:50Z [Term] id: FYPO:0005559 name: thick stable microtubule bundle def: "A physical cellular phenotype in which stable microtubule bundles are thicker than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells." [PMID:26124291, PomBase:mah] synonym: "increased stable microtubule bundle thickness" EXACT [PomBase:mah] synonym: "thick Q-MT bundles" EXACT [PMID:26124291] synonym: "thick quiescent cell microtubule bundle" EXACT [PomBase:vw] synonym: "thick quiescent cell MT bundle" EXACT [PomBase:vw] synonym: "thick stable microtubule array" RELATED [PomBase:vw] synonym: "thick static microtubule bundle" EXACT [GO:0099070] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-08-02T12:25:13Z [Term] id: FYPO:0005560 name: thin stable microtubule bundle def: "A physical cellular phenotype in which stable microtubule bundles are thinner than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells." [PMID:26124291, PomBase:mah] synonym: "decreased stable microtubule bundle thickness" EXACT [PomBase:mah] synonym: "thin Q-MT bundles" EXACT [PMID:26124291] synonym: "thin quiescent cell microtubule bundle" EXACT [PomBase:vw] synonym: "thin quiescent cell MT bundle" EXACT [PomBase:vw] synonym: "thin stable microtubule array" RELATED [PomBase:vw] synonym: "thin static microtubule bundle" EXACT [GO:0099070] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-08-02T12:30:44Z [Term] id: FYPO:0005561 name: long stable microtubule bundle def: "A physical cellular phenotype in which stable microtubule bundles are longer than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells." [PMID:26124291, PomBase:mah] synonym: "elongated stable microtubule bundle" EXACT [PomBase:mah] synonym: "increased stable microtubule bundle length" EXACT [PomBase:mah] synonym: "long Q-MT bundles" EXACT [PMID:26124291] synonym: "long quiescent cell microtubule bundle" EXACT [PomBase:vw] synonym: "long quiescent cell MT bundle" EXACT [PomBase:vw] synonym: "long stable microtubule array" RELATED [PomBase:vw] synonym: "long static microtubule bundle" EXACT [GO:0099070] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-08-02T12:32:46Z [Term] id: FYPO:0005562 name: short stable microtubule bundle def: "A physical cellular phenotype in which stable microtubule bundles are shorter than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells." [PMID:26124291, PomBase:mah] synonym: "decreased stable microtubule bundle length" EXACT [PomBase:mah] synonym: "short Q-MT bundles" EXACT [PMID:26124291] synonym: "short quiescent cell microtubule bundle" EXACT [PomBase:vw] synonym: "short quiescent cell MT bundle" EXACT [PomBase:vw] synonym: "short stable microtubule array" RELATED [PomBase:vw] synonym: "short static microtubule bundle" EXACT [GO:0099070] is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-08-02T12:32:51Z [Term] id: FYPO:0005563 name: long, thick stable microtubule bundle def: "A physical cellular phenotype in which stable microtubule bundles are longer and thicker than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells." [PMID:26124291, PomBase:mah] synonym: "elongated, thick stable microtubule bundle" EXACT [PomBase:mah] synonym: "increased stable microtubule bundle length and thickness" EXACT [PomBase:mah] synonym: "long, thick Q-MT bundles" EXACT [PMID:26124291] synonym: "long, thick quiescent cell microtubule bundle" EXACT [PomBase:vw] synonym: "long, thick quiescent cell MT bundle" EXACT [PomBase:vw] synonym: "long, thick stable microtubule array" RELATED [PomBase:vw] synonym: "long, thick static microtubule bundle" EXACT [GO:0099070] is_a: FYPO:0005559 ! thick stable microtubule bundle is_a: FYPO:0005561 ! long stable microtubule bundle created_by: midori creation_date: 2016-08-02T12:36:59Z [Term] id: FYPO:0005564 name: short, thin stable microtubule bundle def: "A physical cellular phenotype in which stable microtubule bundles are shorter and thinner than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells." [PMID:26124291, PomBase:mah] synonym: "decreased stable microtubule bundle length and thickness" EXACT [PomBase:mah] synonym: "short, thin Q-MT bundles" EXACT [PMID:26124291] synonym: "short, thin quiescent cell microtubule bundle" EXACT [PomBase:vw] synonym: "short, thin quiescent cell MT bundle" EXACT [PomBase:vw] synonym: "short, thin stable microtubule array" RELATED [PomBase:vw] synonym: "short, thin static microtubule bundle" EXACT [GO:0099070] is_a: FYPO:0005560 ! thin stable microtubule bundle is_a: FYPO:0005562 ! short stable microtubule bundle created_by: midori creation_date: 2016-08-02T12:37:56Z [Term] id: FYPO:0005565 name: abnormal microtubule bundle during G0 to G1 transition def: "A physical cellular phenotype in which the amount, distribution, or morphology of microtubule bundles is abnormal when the cell undergoes transition from G0 phase to G1." [PMID:26124291, PomBase:mah] synonym: "abnormal microtubule array during G0 to G1 transition" RELATED [PomBase:vw] synonym: "abnormal microtubule bundle during cell cycle re-entry" EXACT [PomBase:mah] synonym: "abnormal microtubule bundle during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "abnormal microtubule bundle during exit from cell quiescence" EXACT [PomBase:mah] synonym: "abnormal microtubule bundle during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "abnormal microtubule bundle during recovery from quiescence" EXACT [PomBase:vw] synonym: "abnormal microtubule bundle physical object quality during G0 to G1 transition" EXACT [PomBase:mah] synonym: "abnormal MT bundle during G0 to G1 transition" EXACT [PomBase:mah] is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-08-02T12:39:00Z [Term] id: FYPO:0005566 name: T-shaped cell def: "A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T. Cell length is normal." [PomBase:mah, PomBase:vw] comment: One distinction between T-shaped and other branched cells is that in T-shaped cells the new growth zone forms before NETO. A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell morphology, T shaped" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape relationship: output_of FYPO:0005568 ! abnormal cell polarity created_by: midori creation_date: 2016-08-02T12:42:17Z [Term] id: FYPO:0005567 name: T-shaped cell during G0 to G1 transition def: "A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell undergoes transition from G0 phase to G1. Cell length is normal." [PomBase:mah, PomBase:vw] comment: A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell morphology, T shaped during G0 to G1 transition" EXACT [PomBase:mah] synonym: "T-shaped cell during cell cycle re-entry at G1" EXACT [PomBase:mah] synonym: "T-shaped cell during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "T-shaped cell during exit from cell quiescence into G1" EXACT [PomBase:mah] synonym: "T-shaped cell during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "T-shaped cell during recovery from quiescence following G1 arrest" EXACT [PomBase:mah] synonym: "T-shaped cell during recovery from quiescence into G1" EXACT [PomBase:vw] is_a: FYPO:0005810 ! T-shaped cell during recovery from quiescence created_by: midori creation_date: 2016-08-02T12:43:35Z [Term] id: FYPO:0005568 name: abnormal cell polarity def: "A cellular process phenotype in which the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] synonym: "abnormal cell polarity process" EXACT [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity" EXACT [PomBase:mah] synonym: "cell polarity defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2016-08-02T12:50:00Z [Term] id: FYPO:0005569 name: abnormal cell polarity during G0 to G1 transition def: "A cellular process phenotype in which the establishment or maintenance of cell polarity is abnormal when the cell undergoes transition from G0 phase to G1." [PomBase:mah] synonym: "abnormal cell polarity during cell cycle re-entry" EXACT [PomBase:mah] synonym: "abnormal cell polarity during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "abnormal cell polarity during exit from cell quiescence" EXACT [PomBase:mah] synonym: "abnormal cell polarity during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "abnormal cell polarity during recovery from quiescence" EXACT [PomBase:vw] synonym: "abnormal cell polarity process during G0 to G1 transition" EXACT [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity during G0 to G1 transition" EXACT [PomBase:mah] synonym: "cell polarity defects during G0 to G1 transition" EXACT [PomBase:mah] is_a: FYPO:0005568 ! abnormal cell polarity created_by: midori creation_date: 2016-08-02T12:54:26Z [Term] id: FYPO:0005570 name: abnormal protein localization to cell periphery during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell periphery and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell periphery during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell periphery during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0006533 ! abnormal protein localization to cell periphery created_by: midori creation_date: 2016-08-02T13:04:15Z [Term] id: FYPO:0005571 name: abolished protein localization to cell periphery during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell periphery during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from cell periphery during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to cell periphery abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0005570 ! abnormal protein localization to cell periphery during vegetative growth created_by: midori creation_date: 2016-08-02T13:04:23Z [Term] id: FYPO:0005572 name: normal protein localization to cell periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell periphery" EXACT [PomBase:mah] synonym: "normal protein localization to cell periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cell periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2016-08-02T13:13:28Z [Term] id: FYPO:0005573 name: abnormal nuclear transport def: "A cellular process phenotype in which nuclear transport is abnormal." [PomBase:mah] synonym: "nuclear transport: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2016-08-02T13:31:25Z [Term] id: FYPO:0005574 name: abnormal nuclear transport during meiosis def: "A cellular process phenotype in which nuclear transport is abnormal during one or both meiotic nuclear divisions." [PomBase:mah] synonym: "abnormal nuclear transport during meiotic nuclear division" RELATED [GO:0140013] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0005573 ! abnormal nuclear transport created_by: midori creation_date: 2016-08-02T13:33:35Z [Term] id: FYPO:0005575 name: growth auxotrophic for magnesium def: "Auxotrophy in which a cell requires magnesium ions in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for magnesium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for magnesium during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for magnesium ion" EXACT [PomBase:mah] synonym: "magnesium auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2016-08-02T13:49:30Z [Term] id: FYPO:0005576 name: decreased protein localization to chromatin during meiotic cell cycle def: "A cell phenotype in which the localization of a protein to chromatin is decreased during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin during meiotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004094 ! abnormal protein localization during meiotic cell cycle is_a: FYPO:0006631 ! decreased protein localization to chromatin created_by: midori creation_date: 2016-08-03T13:36:16Z [Term] id: FYPO:0005577 name: decreased protein phosphorylation during meiotic cell cycle def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal during the meiotic cell cycle." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "reduced protein phosphorylation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0002679 ! decreased protein phosphorylation is_a: FYPO:0006765 ! abnormal protein phosphorylation during meiotic cell cycle created_by: midori creation_date: 2016-08-03T13:38:51Z [Term] id: FYPO:0005578 name: normal intergenic meiotic recombination def: "A cellular process phenotype in which the occurrence of intergenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intergenic meiotic recombination reflects crossovers between homologous chromosomes." [PMID:25579976, PomBase:mah] synonym: "normal meiotic intergenic recombination" EXACT [PomBase:al] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2016-08-03T13:41:45Z [Term] id: FYPO:0005579 name: decreased meiotic sister chromatid cohesion at centromere def: "A cellular process phenotype in which cohesion between sister chromatids is decreased in centromeric regions during meiosis." [PomBase:mah] synonym: "decreased meiotic sister chromatid cohesion, centromeric" EXACT [GO:0051754] synonym: "decreased sister chromatid cohesion at centromere during meiosis" EXACT [PomBase:mah] synonym: "reduced meiotic sister chromatid cohesion at centromere" EXACT [PomBase:mah] is_a: FYPO:0002092 ! abnormal meiotic sister chromatid cohesion created_by: midori creation_date: 2016-08-03T13:43:23Z [Term] id: FYPO:0005580 name: decreased level of lipid metabolism gene mRNA during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more lipid metabolism RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) during a cellular response to hypoxia. Lipid metabolism RNAs are transcribed from genes whose products are involved in any lipid metabolic process." [PMID:27053105, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of lipid metabolism gene mRNA during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of lipid metabolism gene mRNA during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of lipid metabolism gene RNA during cellular response to hypoxia" EXACT [PomBase:mah] synonym: "decreased level of lipid metabolism gene transcripts during cellular response to hypoxia" EXACT [PomBase:vw] synonym: "decreased lipid metabolism gene mRNA accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "reduced level of lipid metabolism gene mRNA during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0004880 ! decreased level of lipid metabolism gene mRNA during vegetative growth created_by: midori creation_date: 2016-08-03T14:40:42Z [Term] id: FYPO:0005581 name: short glycerophospholipids def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains glycerophospholipids that have shorter fatty acid chain residues than normal." [PMID:27053105, PomBase:mah] synonym: "decreased glycerophospholipid fatty acid chain length" EXACT [PomBase:mah] synonym: "reduced glycerophospholipid fatty acid chain length" EXACT [PomBase:mah] synonym: "short glycerophospholipids during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short glycerophospholipids during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-08-03T15:05:23Z [Term] id: FYPO:0005582 name: normal monoacylglycerol phosphate chain length def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains monoacylglycerol phosphates (also called lysophospholipids) that have normal length fatty acid chain residues." [PMID:27053105, PomBase:mah] synonym: "normal lysophospholipid chain length" EXACT [PomBase:al] synonym: "normal lysophospholipid fatty acid chain length" EXACT [PomBase:mah] synonym: "normal monoacylglycerol phosphate chain length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal monoacylglycerol phosphate chain length during vegetative growth" EXACT [PomBase:mah] synonym: "normal monoacylglycerol phosphate fatty acid chain length" EXACT [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2016-08-03T15:07:02Z [Term] id: FYPO:0005583 name: increased fatty acid saturation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains higher levels of saturated fatty acids, and lower levels of unsaturated fatty acids, than normal." [PMID:27053105, PomBase:mah] synonym: "increased fatty acid saturation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased fatty acid saturation during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of saturated fatty acids and decreased level of unsaturated fatty acids" EXACT [PomBase:mah] synonym: "increased saturated:unsaturated fatty acid ratio" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-08-03T15:09:03Z [Term] id: FYPO:0005584 name: decreased cellular diglyceride level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more diglycerides measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular DAG level" EXACT [PomBase:mah] synonym: "decreased cellular diacylglycerol level" EXACT [CHEBI:18035] synonym: "decreased cellular diglyceride level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular diglyceride level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased diglyceride accumulation" RELATED [PomBase:mah] synonym: "reduced cellular diglyceride level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:22:32Z [Term] id: FYPO:0005585 name: decreased cellular triglyceride level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular TAG level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular triacylglycerol level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular triglyceride level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased triglyceride accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced cellular triglyceride level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:22:55Z [Term] id: FYPO:0005586 name: increased cellular phosphatidylethanolamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular PE level" EXACT [PomBase:mah] synonym: "increased cellular phosphatidylethanolamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphatidylethanolamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased phosphatidylethanolamine accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:27:21Z [Term] id: FYPO:0005587 name: increased cellular phosphatidic acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphatidic acid measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phosphatidic acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphatidic acid level during vegetative growth" EXACT [PomBase:mah] synonym: "increased phosphatidic acid accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:37:24Z [Term] id: FYPO:0005588 name: decreased cellular phosphoinositide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell is lower than normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." [PomBase:mah] synonym: "decreased cellular phosphoinositide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphoinositide level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PI level" RELATED [PomBase:al] synonym: "decreased PI accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphoinositide level" EXACT [PomBase:mah] is_a: FYPO:0001290 ! altered cellular phosphoinositide level is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:38:41Z [Term] id: FYPO:0005589 name: normal cellular phosphatidylserine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular phosphatidylserine accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylserine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylserine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular PS level" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:40:17Z [Term] id: FYPO:0005590 name: normal cellular cardiolipin level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cardiolipin measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular cardiolipin accumulation" RELATED [PomBase:mah] synonym: "normal cellular cardiolipin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular cardiolipin level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:40:58Z [Term] id: FYPO:0005591 name: decreased cellular lysophosphatidylcholine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lysophosphatidylcholine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular lysophosphatidylcholine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular lysophosphatidylcholine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lysophosphatidylcholine accumulation" RELATED [PomBase:al] synonym: "reduced cellular lysophosphatidylcholine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:42:36Z [Term] id: FYPO:0005592 name: decreased cellular lysophosphatidylethanolamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lysophosphatidylethanolamine level measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular lysophosphatidylethanolamine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lysophosphatidylethanolamine accumulation" RELATED [PomBase:al] synonym: "reduced cellular lysophosphatidylethanolamine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:43:18Z [Term] id: FYPO:0005593 name: increased cellular inositol phosphorylceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of inositol phosphorylceramide measured in a cell is higher than normal." [PomBase:mah] comment: Note that, because doxorubicin is not synthesized by fission yeast cells, the amount measured in a cell reflects uptake from the growth medium. synonym: "increased cellular inositol phosphorylceramide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular inositol phosphorylceramide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular IPC level" EXACT [PMID:34114004] synonym: "increased inositol phosphorylceramide accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-03T15:44:41Z [Term] id: FYPO:0005594 name: increased protein localization to chromatin at rDNA replication fork barrier def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at a replication fork pausing site within the eukaryotic rDNA repeat spacer is increased." [PMID:25965521, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at rDNA replication fork barrier" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at rDNA replication fork barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at rDNA replication fork barrier during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at ribosomal DNA replication fork barrier" EXACT [PomBase:mah] is_a: FYPO:0004032 ! increased protein localization to chromatin at rDNA created_by: midori creation_date: 2016-08-05T11:18:48Z [Term] id: FYPO:0005595 name: normal cellular ceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a ceramide measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular ceramide accumulation" RELATED [PomBase:mah] synonym: "normal cellular ceramide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular ceramide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2016-08-08T12:53:49Z [Term] id: FYPO:0005596 name: increased protein localization to spindle during meiosis I def: "A cell phenotype in which the localization of a protein to the spindle is increased during the first meiotic nuclear division." [PMID:26696398, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to spindle during meiosis I" EXACT [PomBase:mah] synonym: "increased protein localization to meiosis I spindle" EXACT [PomBase:al] synonym: "increased protein localization to meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "increased protein localization to spindle during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle created_by: midori creation_date: 2016-08-10T14:29:29Z [Term] id: FYPO:0005597 name: abnormal protein localization to centromere def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the centromere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to centromere" EXACT [PomBase:mah] synonym: "abnormal protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2016-08-10T14:34:41Z [Term] id: FYPO:0005598 name: increased protein localization to centromere during meiotic cell cycle def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is increased during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromere during meiotic cell cycle" EXACT [PomBase:mah] synonym: "increased protein localisation to chromosome, centromeric region during meiotic cell cycle" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centric region during meiotic cell cycle" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centromeric region during meiotic cell cycle" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0006239 ! increased protein localization to centromere is_a: FYPO:0006529 ! abnormal protein localization to centromere during meiotic cell cycle created_by: midori creation_date: 2016-08-10T14:37:32Z [Term] id: FYPO:0005599 name: increased duration of meiosis I def: "A cellular process phenotype in which the duration of the first meiotic nuclear division is longer than normal." [PomBase:mah] synonym: "delayed meiosis I progression" RELATED [PomBase:mah] synonym: "increased duration of first meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased duration of meiosis I progression" EXACT [PomBase:mah] synonym: "prolonged meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003603 ! abnormal meiosis I created_by: midori creation_date: 2016-08-10T14:42:12Z [Term] id: FYPO:0005600 name: abnormal chromosome morphology def: "A physical cellular phenotype in which the size, shape, or structure of one or more chromosomes is abnormal." [PomBase:mah] comment: Note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2016-08-10T14:44:23Z [Term] id: FYPO:0005601 name: abnormal chromosome morphology during meiotic cell cycle def: "A physical cellular phenotype in which the size, shape, or structure of one or more chromosomes is abnormal during the meiotic cell cycle." [PomBase:mah] comment: Note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. is_a: FYPO:0005600 ! abnormal chromosome morphology relationship: output_of FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2016-08-10T14:45:48Z [Term] id: FYPO:0005602 name: normal subtelomeric heterochromatin RNA level def: "A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin forming regions is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:25356590, PMID:27183912] synonym: "normal subtelomere-derived RNA level" EXACT [] synonym: "normal subtelomere-derived RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal subtelomere-derived RNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2016-08-10T14:59:21Z [Term] id: FYPO:0005603 name: increased duration of mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to methyl methanesulfonate." [PomBase:mah] synonym: "delayed mitotic DNA damage checkpoint deactivation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "increased duration of mitotic DNA damage checkpoint during cellular response to MMS" EXACT [PomBase:mah] synonym: "prolonged mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0002341 ! increased duration of mitotic DNA damage checkpoint is_a: FYPO:0005268 ! abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate created_by: midori creation_date: 2016-08-10T15:10:47Z [Term] id: FYPO:0005604 name: increased duration of Rad52 focus presence during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which sites at which the protein Rad52 accumulates remain present for longer than normal during a cellular response to ionizing radiation." [PMID:27098497, PomBase:mah] synonym: "delayed peak level of Rad52 foci during cellular response to ionizing radiation" RELATED [PMID:27098497] synonym: "increased duration of Rad22 focus presence during cellular response to ionizing radiation" EXACT [PMID:22927644] synonym: "increased duration of Rad52 focus presence during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of Rad52 focus presence during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased persistence of Rad52 foci during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "prolonged Rad52 focus presence during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0007191 ! increased duration of Rad52 focus presence during vegetative growth created_by: midori creation_date: 2016-08-10T15:12:20Z [Term] id: FYPO:0005605 name: increased duration of Ssb1 focus presence during cellular response to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which sites at which the protein Ssb1 accumulates remain present for longer than normal during a cellular response to ionizing radiation." [PMID:27098497, PomBase:mah] synonym: "delayed peak level of Ssb1 foci" RELATED [PMID:27098497] synonym: "increased duration of Rad11 focus presence during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "increased duration of RPA focus presence during cellular response to ionizing radiation" EXACT [PMID:22927644] synonym: "increased duration of Rpa1 focus presence during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "increased duration of Ssb1 focus presence during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of Ssb1 focus presence during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased persistence of Ssb1 foci during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "prolonged Ssb1 focus presence during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2016-08-10T15:14:45Z [Term] id: FYPO:0005606 name: delayed onset of protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred begins later than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to DSB site" EXACT [PomBase:al] synonym: "delayed onset of protein localization to site of double-strand break" EXACT [GO:0035861, PomBase:mah] synonym: "delayed protein localization to double-strand break site" EXACT [PomBase:mah] is_a: FYPO:0002473 ! abnormal protein localization to double-strand break site created_by: midori creation_date: 2016-08-10T15:18:05Z [Term] id: FYPO:0005607 name: abnormal histone H2B-K119 ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is abnormal. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PomBase:mah] synonym: "abnormal histone H2B conserved C-terminal lysine ubiquitination" EXACT [GO:0071894] synonym: "abnormal histone H2B-K119 ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002921 ! abnormal histone ubiquitination during vegetative growth created_by: midori creation_date: 2016-08-10T15:21:14Z [Term] id: FYPO:0005608 name: decreased histone H2B-K119 ubiquitination at double-strand break site during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B occurs to a lower extent than normal in regions surrounding double-strand DNA breaks. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PMID:27098497, PomBase:mah] synonym: "decreased histone H2B conserved C-terminal lysine ubiquitination at double-strand break site during vegetative growth" EXACT [GO:0071894] synonym: "decreased histone H2B-K119 ubiquitination at double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H2B-K119 ubiquitination at DSB during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H2B-K119 ubiquitination at site of double-strand break during vegetative growth" EXACT [GO:0035861] synonym: "reduced histone H2B-K119 ubiquitination at double-strand break during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002768 ! decreased protein ubiquitination during vegetative growth is_a: FYPO:0007386 ! decreased histone H2B-K119 ubiquitination during vegetative growth created_by: midori creation_date: 2016-08-10T15:21:54Z [Term] id: FYPO:0005609 name: decreased spatial extent of histone H2B-K119 ubiquitination at double-strand break site during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B occurs over a smaller portion of the chromosome than normal in regions surrounding double-strand DNA breaks. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PMID:27098497, PomBase:mah] synonym: "decreased spatial extent of histone H2B conserved C-terminal lysine ubiquitination at double-strand break site during vegetative growth" EXACT [GO:0071894] synonym: "decreased spatial extent of histone H2B-K119 ubiquitination at double-strand break site during mitotic cell cycle during vegetative growth" RELATED [PomBase:mah] synonym: "decreased spatial extent of histone H2B-K119 ubiquitination at DSB during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spatial extent of histone H2B-K119 ubiquitination at site of double-strand break during vegetative growth" EXACT [GO:0035861] synonym: "reduced spatial extent of histone H2B-K119 ubiquitination at double-strand break during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005607 ! abnormal histone H2B-K119 ubiquitination during vegetative growth created_by: midori creation_date: 2016-08-10T15:26:24Z [Term] id: FYPO:0005610 name: decreased spatial extent of protein localization to double-strand break site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to a smaller portion of the chromosome than normal in the region of a chromosome at which a DNA double-strand break has occurred." [PMID:27098497, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased spatial extent of protein localisation to double-strand break site" EXACT [PomBase:mah] synonym: "decreased spatial extent of protein localization to double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spatial extent of protein localization to double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spatial extent of protein localization to DSB" EXACT [PomBase:mah] synonym: "decreased spatial extent of protein localization to site of double-strand break" EXACT [GO:0035861] synonym: "reduced spatial extent of protein localization to double-strand break" EXACT [PomBase:mah] is_a: FYPO:0002473 ! abnormal protein localization to double-strand break site is_a: FYPO:0007465 ! altered spatial extent of protein localization to chromatin created_by: midori creation_date: 2016-08-10T15:29:19Z [Term] id: FYPO:0005611 name: increased H4-K20 dimethylation at double-strand break site during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 occurs to a greater extent than normal in the region of a chromosome at which a DNA double-strand break has occurred." [PomBase:mah] synonym: "increased H4-K20 dimethylation at DSB during vegetative growth" EXACT [PomBase:mah] synonym: "increased H4K20me2 at double-strand break site during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K20 dimethylation at double-strand break site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K20 dimethylation at double-strand break site during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "increased histone H4-K20 dimethylation at site of double-strand break during vegetative growth" EXACT [GO:0035861] synonym: "increased histone lysine H4-K20 dimethylation at double-strand break site during vegetative growth" EXACT [GO:0034772, PomBase:mah] is_a: FYPO:0000869 ! increased histone methylation during vegetative growth is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: midori creation_date: 2016-08-10T15:33:34Z [Term] id: FYPO:0005612 name: normal protein localization to nuclear envelope def: "A cell phenotype in which the localization of a protein to the nuclear envelope is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear envelope" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2016-08-17T10:41:43Z [Term] id: FYPO:0005613 name: normal protein localization to nuclear envelope during G0 to G1 transition def: "A cell phenotype in which the localization of a protein to the nuclear envelope is normal (i.e. indistinguishable from wild type) when the cell undergoes transition from G0 phase to G1." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear envelope during G0 to G1 transition" EXACT [PomBase:mah] synonym: "normal protein localization after G0 to G1 transition" EXACT [PomBase:vw] synonym: "normal protein localization during cell cycle re-entry" EXACT [PomBase:mah] synonym: "normal protein localization during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "normal protein localization during exit from cell quiescence" EXACT [PomBase:mah] synonym: "normal protein localization during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "normal protein localization during recovery from quiescence" EXACT [PomBase:vw] synonym: "normal protein relocalization to nuclear envelope during G0 to G1 transition" NARROW [PomBase:mah] is_a: FYPO:0005612 ! normal protein localization to nuclear envelope created_by: midori creation_date: 2016-08-17T10:43:30Z [Term] id: FYPO:0005614 name: normal protein phosphorylation during cellular response to bleomycin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to bleomycin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-08-17T11:13:09Z [Term] id: FYPO:0005615 name: abnormal protein phosphorylation during cellular response to bleomycin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal during a cellular response to bleomycin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein phosphorylation during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein phosphorylation during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000775 ! abnormal protein phosphorylation during vegetative growth created_by: midori creation_date: 2016-08-17T11:22:31Z [Term] id: FYPO:0005616 name: abolished protein phosphorylation during cellular response to bleomycin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to bleomycin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to bleomycin" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth is_a: FYPO:0005615 ! abnormal protein phosphorylation during cellular response to bleomycin created_by: midori creation_date: 2016-08-17T11:23:21Z [Term] id: FYPO:0005617 name: decreased protein phosphorylation during cellular response to bleomycin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to bleomycin." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to bleomycin" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth is_a: FYPO:0005615 ! abnormal protein phosphorylation during cellular response to bleomycin created_by: midori creation_date: 2016-08-17T11:26:44Z [Term] id: FYPO:0005618 name: increased duration of meiotic recombination double-strand break repair def: "A cellular process phenotype in which the duration of repair of double-strand breaks formed as part of meiotic recombination is longer than normal." [PMID:18378696, PomBase:mah] synonym: "increased duration of double-strand break repair during meiotic recombination" EXACT [PomBase:mah] synonym: "increased duration of double-strand break repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "increased duration of DSB repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "prolonged meiotic recombination double-strand break repair" EXACT [PomBase:mah] is_a: FYPO:0005139 ! abnormal meiotic recombination double-strand break repair created_by: midori creation_date: 2016-08-17T11:35:10Z [Term] id: FYPO:0005619 name: increased level of sumoylated protein in cell def: "A cell phenotype in which the amount of sumoylated protein measured in the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased accumulation of sumoylated protein in cell" RELATED [PomBase:mah] synonym: "increased level of sumoylated protein in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of sumoylated protein in cell during vegetative growth" EXACT [PomBase:mah] synonym: "increased sumoylated protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2016-08-17T11:42:55Z [Term] id: FYPO:0005620 name: increased SUMO chain length def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains sumoylated proteins that have longer poly-SUMO chains than normal." [PMID:22730331, PomBase:mah] synonym: "increased SUMO chain length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased SUMO chain length during vegetative growth" EXACT [PomBase:mah] synonym: "increased sumoylated protein SUMO chain length" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-08-17T11:52:47Z [Term] id: FYPO:0005621 name: increased topoisomerase-DNA adduct level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains more adducts formed between a topoisomerase and DNA than normal." [PMID:22730331, PomBase:mah] synonym: "increased Top1-DNA adduct level" NARROW [PMID:22730331] synonym: "increased Top1cc level" NARROW [PMID:22730331] synonym: "increased topoisomerase I-DNA adduct level" NARROW [PomBase:mah] synonym: "increased topoisomerase-DNA adduct level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased topoisomerase-DNA adduct level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2016-08-17T11:54:47Z [Term] id: FYPO:0005622 name: normal topoisomerase-DNA adduct level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains a normal (i.e. indistinguishable from wild type) amount of adducts formed between a topoisomerase and DNA." [PMID:22730331, PomBase:mah] synonym: "normal Top1-DNA adduct level" NARROW [PMID:22730331] synonym: "normal Top1cc level" NARROW [PMID:22730331] synonym: "normal topoisomerase I-DNA adduct level" NARROW [PomBase:mah] synonym: "normal topoisomerase-DNA adduct level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal topoisomerase-DNA adduct level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2016-08-17T11:57:28Z [Term] id: FYPO:0005623 name: sensitive to UV during late mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light late in G2 phase of the mitotic cell cycle." [PMID:26652183, PomBase:mah] synonym: "decreased growth during cellular response to UV during late mitotic G2 phase" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to UV during late mitotic G2 phase" EXACT [PomBase:mah] synonym: "hypersensitive to UV during late mitotic G2 phase" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation during late mitotic G2 phase" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light during late mitotic G2 phase" EXACT [PomBase:mah] synonym: "sensitive to UV during late G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to UV during late G2 phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000268 ! sensitive to UV during vegetative growth created_by: midori creation_date: 2016-08-22T11:44:01Z [Term] id: FYPO:0005624 name: sensitive to UV during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light during S phase of the mitotic cell cycle." [PMID:26652183, PomBase:mah] synonym: "decreased growth during cellular response to UV during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to UV during mitotic S phase" EXACT [PomBase:mah] synonym: "hypersensitive to UV during mitotic S phase" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation during mitotic S phase" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light during mitotic S phase" EXACT [PomBase:mah] synonym: "sensitive to UV during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to UV during S phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000268 ! sensitive to UV during vegetative growth created_by: midori creation_date: 2016-08-22T11:46:31Z [Term] id: FYPO:0005625 name: normal viability following cellular response to UV during mitotic S phase def: "A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to ultraviolet light during S phase of the mitotic cell cycle." [PMID:26652183, PomBase:mah] synonym: "normal cell population viability following cellular response to UV during mitotic S phase" EXACT [PomBase:mah] synonym: "normal viability following cellular response to ultraviolet light during mitotic S phase" EXACT [PomBase:mah] synonym: "normal viability following cellular response to UV during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal viability following UV exposure during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0004662 ! normal viability following cellular response to UV created_by: midori creation_date: 2016-08-22T11:48:02Z [Term] id: FYPO:0005626 name: normal mitotic G2 DNA damage checkpoint during cellular response to UV during mitotic S phase def: "A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light during S phase of the mitotic cell cycle. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage." [PMID:26652183, PomBase:mah] synonym: "normal G2 DNA damage checkpoint during cellular response to UV during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint activation during cellular response to UV during mitotic S phase" EXACT [PomBase:al] synonym: "normal mitotic G2 DNA damage checkpoint during cellular response to S phase exposure to UV" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint during cellular response to ultraviolet light during mitotic S phase" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint during cellular response to UV during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint response after UV irradiation during S phase" EXACT [PMID:26652183] is_a: FYPO:0005299 ! normal mitotic G2 DNA damage checkpoint during cellular response to UV created_by: midori creation_date: 2016-08-22T11:51:14Z [Term] id: FYPO:0005627 name: increased duration of mitotic DNA damage checkpoint during cellular response to UV during mitotic S phase def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ultraviolet (UV) light, when cells are exposed to UV during S phase of the mitotic cell cycle." [PMID:26652183, PomBase:mah] synonym: "delayed DNA damage checkpoint deactivation during cellular response to UV during mitotic S phase" EXACT [PomBase:mah] synonym: "increased duration of mitotic DNA damage checkpoint after UV irradiation during S phase" EXACT [PMID:26652183] synonym: "increased duration of mitotic DNA damage checkpoint during cellular response to S phase exposure to UV" EXACT [PomBase:mah] synonym: "prolonged DNA damage checkpoint during cellular response to UV during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0003445 ! increased duration of mitotic DNA damage checkpoint during cellular response to UV created_by: midori creation_date: 2016-08-22T11:55:41Z [Term] id: FYPO:0005628 name: decreased rate of cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of cell separation after cytokinesis is decreased." [PomBase:mah] synonym: "decreased rate of cell separation after cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of mitotic cytokinetic cell separation" EXACT [PomBase:mah] synonym: "decreased rate of septum digestion after cytokinesis" EXACT [GO:0000920] synonym: "reduced rate of cell separation after cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: midori creation_date: 2016-08-22T15:10:39Z [Term] id: FYPO:0005629 name: increased cellular HMW SUMO conjugate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polySUMO conjugation is greater than normal." [PMID:26221037, PomBase:mah] synonym: "accumulation of high molecular mass SUMO conjugates" EXACT [PomBase:vw] synonym: "accumulation of high molecular weight SUMO conjugates" EXACT [PomBase:vw] synonym: "accumulation of HMW SUMO conjugates" EXACT [PomBase:vw] synonym: "increased cellular high molecular mass SUMO conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular high molecular weight SUMO conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular HMW SUMO conjugate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular HMW SUMO conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased HMW SUMO conjugate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2016-08-22T15:17:08Z [Term] id: FYPO:0005630 name: decreased cellular HMW SUMO conjugate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polySUMO conjugation is lower than normal." [PMID:26221037, PomBase:mah] synonym: "decreased cellular high molecular mass SUMO conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular high molecular weight SUMO conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular HMW SUMO conjugate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular HMW SUMO conjugate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased HMW SUMO conjugate accumulation" RELATED [PomBase:mah] synonym: "reduced cellular HMW SUMO conjugate level" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2016-08-22T15:18:46Z [Term] id: FYPO:0005631 name: decreased rate of protein degradation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein degradation is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased rate of protein breakdown during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased rate of protein catabolic process during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased rate of protein catabolism during vegetative growth" EXACT [GO:0030163, PomBase:mah] synonym: "decreased rate of protein degradation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced rate of protein degradation" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth created_by: midori creation_date: 2016-08-22T15:20:17Z [Term] id: FYPO:0005633 name: sister kinetochore dissociation in meiotic metaphase I, normal chromosome segregation in meiosis I, and sister chromatid non-disjunction in meiosis II def: "A physical cellular phenotype in which sister kinetochores separate during the first meiotic nuclear division, homologous chromosomes undergo normal reductional division, but sister chromatids divide unequally in meiosis II. Normally sister kinetochores remain together until meiosis II. Normally sister kinetochores remain together until meiosis II." [PMID:21920317, PomBase:vw] comment: This term describes the premature separation of paired, intact sister kinetochores. It has a related synonym using "split kinetochores" because that phrase is often used in the literature to describe this phenotype. It should not be confused with the FYPO terms that have "split kinetochore" in the names, because those names refer to cases where a single kinetochore has broken into parts. synonym: "abnormal chromosome segregation during first meiotic nuclear division with premature sister kinetochore separation, reductional chromosome separation, and unequal sister chromatid division" EXACT [PomBase:mah] synonym: "abnormal chromosome segregation during meiosis I with premature sister kinetochore separation, reductional chromosome separation, and unequal sister chromatid division" EXACT [PomBase:mah] synonym: "precocious centromeric dissociation during meiosis I and normal chromosome division in meiosis I, and unequal sister chromatid segregation in meiosis II" EXACT [PomBase:vw] synonym: "premature sister kinetochore separation and normal chromosome disjunction in meiosis I, and unequal sister chromatid disjunction in meiosis II" EXACT [PomBase:vw] is_a: FYPO:0003182 ! sister chromatid nondisjunction at meiosis II is_a: FYPO:0005648 ! sister kinetochore dissociation in meiotic metaphase I created_by: midori creation_date: 2016-08-24T14:57:44Z [Term] id: FYPO:0005634 name: sister kinetochore dissociation in meiotic metaphase I with equational sister chromatid segregation in meiosis I def: "A cellular process phenotype in which sister kinetochores become separated during the first meiotic nuclear division, and sister chromatids subsequently separate to result in equational segregation. Equational sister chromatid separation is caused by bi-orientated attachment of sister chromatids." [PMID:21920317, PomBase:mah, PomBase:vw] comment: Sister kinetochores may separate in meiosis I due to problems with either sister chromatid cohesion or kinetochore attachment to microtubules. Therefore consider also annotating to 'abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation' (FYPO:0000209), 'decreased meiotic sister chromatid cohesion' (FYPO:0002093), or 'merotelic kinetochore attachment during meiosis I' (FYPO:0005638). This term describes the premature separation of paired, intact sister kinetochores. It has a related synonym using "split kinetochores" because that phrase is often used in the literature to describe this phenotype. It should not be confused with the FYPO terms that have "split kinetochore" in the names, because those names refer to cases where a single kinetochore has broken into parts. synonym: "abnormal chromosome segregation during meiosis I with premature sister kinetochore separation and equational sister chromatid separation" EXACT [PomBase:vw] synonym: "abolished monopolar kinetochore attachment during meiosis I" RELATED [PomBase:vw] synonym: "equational sister chromatid separation during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "equational sister chromatid separation during meiosis I with split kinetochores" RELATED [PomBase:mah] synonym: "equational sister chromatid separation in meiosis I" EXACT [PomBase:vw] synonym: "increased bi-orientated attachment of sister chromatids in meiosis I" RELATED [] is_a: FYPO:0005648 ! sister kinetochore dissociation in meiotic metaphase I is_a: FYPO:0008202 ! equational sister chromatid separation at meiosis I created_by: midori creation_date: 2016-08-24T14:58:54Z [Term] id: FYPO:0005635 name: delayed onset of protein localization to spindle during meiosis I def: "A cell phenotype in which the localization of a protein to the spindle begins later than normal during the first meiotic nuclear division." [PMID:21920317, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to spindle during meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to meiosis I spindle" EXACT [PomBase:al] synonym: "delayed onset of protein localization to meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "delayed protein localization to spindle during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle created_by: midori creation_date: 2016-08-24T15:17:51Z [Term] id: FYPO:0005636 name: delayed onset of protein localization from kinetochore to spindle during meiosis I def: "A cell phenotype in which the localization of a protein from kinetochores to the spindle begins later than normal during the first meiotic nuclear division." [PMID:21920317, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation from kinetochore to spindle during meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of protein localization from kinetochore to meiosis I spindle" EXACT [PomBase:al] synonym: "delayed onset of protein localization from kinetochore to meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of protein localization from kinetochore to spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "delayed onset of protein movement from kinetochore to spindle during meiosis I" RELATED [PomBase:mah] synonym: "delayed protein localization from kinetochore to spindle during meiosis I" EXACT [PomBase:mah] synonym: "delayed protein localization to meiotic spindle from kinetochore during meiosis I" EXACT [PomBase:vw] is_a: FYPO:0005635 ! delayed onset of protein localization to spindle during meiosis I creation_date: 2016-08-24T15:20:36Z [Term] id: FYPO:0005637 name: normal onset of metaphase/anaphase transition of meiosis I def: "A cellular process phenotype in which the metaphase/anaphase transition of the first meiotic nuclear division begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PomBase:mah] synonym: "normal duration of meiosis I metaphase" RELATED [PomBase:mah] synonym: "normal duration of metaphase during meiosis I" RELATED [PomBase:mah] synonym: "normal onset of meiosis I metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "normal onset of metaphase/anaphase transition of first meiotic nuclear division" EXACT [GO:0007127] synonym: "normal timing of meiosis I metaphase/anaphase transition" RELATED [PomBase:mah] is_a: FYPO:0006916 ! normal cell cycle phase transition is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2016-08-24T15:50:11Z [Term] id: FYPO:0005638 name: merotelic kinetochore attachment during meiosis I def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division results in the connection of a single kinetochore to both spindle poles." [PMID:21920317, PomBase:mah] synonym: "merotelic attachment of spindle microtubules to kinetochore during meiosis I" EXACT [PomBase:mah] synonym: "merotelic kinetochore attachment during first meiotic nuclear division" EXACT [GO:0140013] synonym: "merotelic kinetochore attachment during M phase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0000209 ! abnormal attachment of spindle microtubules to kinetochore during meiosis I is_a: FYPO:0002651 ! merotelic kinetochore attachment created_by: midori creation_date: 2016-08-26T13:36:01Z [Term] id: FYPO:0005639 name: normal RNA level during cellular response to iron ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to iron ion starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to iron ion starvation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to iron ion starvation" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to iron ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to iron ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to iron starvation" EXACT [PomBase:mah] synonym: "normal RNA level during iron ion starvation" EXACT [PomBase:al] synonym: "normal transcript level during cellular response to iron ion starvation" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2016-08-26T13:58:55Z [Term] id: FYPO:0005640 name: abnormal meiotic centromere clustering with centromeres dissociated from spindle pole body def: "A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions, such that centromeres dissociate from the spindle pole body, but do not cluster with each other." [PMID:21920317, PomBase:mah] synonym: "abnormal centromere clustering during meiosis with centromeres dissociated from spindle pole body" EXACT [GO:1990571] synonym: "abnormal centromere clustering with centromeres dissociated from SPB during meiotic cell cycle" RELATED [PomBase:al] synonym: "abnormal centromere clustering with centromeres dissociated from spindle pole body during meiosis" EXACT [PomBase:mah] synonym: "abnormal centromere clustering with centromeres dissociated from spindle pole body during meiotic cell cycle" RELATED [PomBase:al] synonym: "abnormal chromosome retrieval during meiosis with centromeres dissociated from spindle pole body" RELATED [PomBase:vw] synonym: "abnormal kinetochore retrieval during meiosis with centromeres dissociated from spindle pole body" RELATED [PomBase:vw] synonym: "abnormal meiotic centromere clustering with centromeres dissociated from SPB" EXACT [PomBase:mah] is_a: FYPO:0004086 ! abnormal meiotic centromere clustering created_by: midori creation_date: 2016-08-26T14:03:26Z [Term] id: FYPO:0005641 name: abnormal chromosome segregation during meiosis I with premature sister kinetochore separation, lagging chromosomes, and normal chromosome separation def: "A cellular process phenotype in which kinetochores become separated during the first meiotic nuclear division, and in which homologous chromosomes do not move towards the spindle poles at the same time during anaphase, but are eventually separated normally." [PMID:21920317, PomBase:mah, PomBase:vw] comment: This term describes the premature separation of paired, intact sister kinetochores. It has a related synonym using "split kinetochores" because that phrase is often used in the literature to describe this phenotype. It should not be confused with the FYPO terms that have "split kinetochore" in the names, because those names refer to cases where a single kinetochore has broken into parts. synonym: "abnormal chromosome segregation during first meiotic nuclear division with premature sister kinetochore separation, lagging chromosomes, and normal chromosome separation" EXACT [PomBase:mah] synonym: "abnormal chromosome segregation during meiosis I with precocious centromeric dissociation, lagging chromosomes, and normal chromosome separation" EXACT [PomBase:vw] synonym: "abnormal chromosome segregation during meiosis I with premature sister kinetochore separation, lagging chromosomes, and normal chromosome segregation" RELATED [PomBase:vw] synonym: "abnormal chromosome segregation during meiosis I with split kinetochores, lagging chromosomes, and normal chromosome separation" RELATED [PomBase:mah] is_a: FYPO:0004159 ! abnormal homologous chromosome segregation is_a: FYPO:0005633 ! sister kinetochore dissociation in meiotic metaphase I, normal chromosome segregation in meiosis I, and sister chromatid non-disjunction in meiosis II relationship: has_part FYPO:0004393 ! lagging chromosomes during meiosis I created_by: midori creation_date: 2016-08-26T14:07:01Z [Term] id: FYPO:0005642 name: abnormal meiotic homologous chromosome biorientation with abnormal kinetochore orientation def: "A cellular process phenotype in which homologous chromosome biorientation is abnormal during meiosis, with chromosomes that are not correctly oriented with the kinetochores facing outwards. Homologous chromosome biorientation is the process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, ensuring that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PMID:21920317, PomBase:mah, PomBase:vw] synonym: "abnormal homologous chromosome biorientation with abnormal kinetochore orientation during meiosis" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome orientation involved in meiotic metaphase I plate congression with abnormal kinetochore orientation" EXACT [GO:0031619] synonym: "abnormal meiotic homologous chromosome biorientation with abnormal kinetochore position" EXACT [PomBase:mah] is_a: FYPO:0003177 ! abnormal meiotic homologous chromosome biorientation created_by: midori creation_date: 2016-08-26T14:19:36Z [Term] id: FYPO:0005643 name: decreased protein localization to cell tip, with protein mislocalized to nucleus and spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased, and an increased amount of the protein is instead detected in the nucleus and at the spindle pole body." [PMID:24478458, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell tip, with protein mislocalized to nucleus and spindle pole body" EXACT [PomBase:mah] synonym: "decreased protein localization to cell end, with protein mislocalized to nucleus and spindle pole body" EXACT [PomBase:mah] synonym: "decreased protein localization to cell tip, with protein mislocalized to nucleus and SPB" EXACT [PomBase:mah] synonym: "decreased protein localization to cell tip, with protein mislocalized to nucleus and spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell tip, with protein mislocalized to nucleus and spindle pole body, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cell tip, with protein mislocalized to nucleus and spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0001586 ! decreased protein localization to cell tip during vegetative growth created_by: midori creation_date: 2016-08-26T14:26:18Z [Term] id: FYPO:0005644 name: normal protein localization to nucleus during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to HU" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2016-08-26T14:28:41Z [Term] id: FYPO:0005645 name: resistance to Cutin-1 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of Cutin-1 (N-carbamoyl-2-(triphenyl-lambda-5-phosphanylidene)acetamide) than normal." [PomBase:mah] comment: Cutin-1 has CAS registry number 53296-08-5. synonym: "resistance to Cutin-1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to Cutin-1 during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to N-carbamoyl-2-(triphenyl-lambda-5-phosphanylidene)acetamide" EXACT [PomBase:mah] synonym: "resistant to Cutin-1" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2016-09-06T13:58:21Z [Term] id: FYPO:0005646 name: abnormal kinetochore morphology def: "A physical cellular phenotype in which the size, shape, or structure of the kinetochore is abnormal." [PomBase:mah] comment: Note that an abnormal kinetochore organization process may, but does not necessarily, result in abnormal kinetochore structure. synonym: "abnormal kinetochore structure" NARROW [PomBase:mah] synonym: "kinetochore defects" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2016-09-06T14:19:52Z [Term] id: FYPO:0005647 name: split kinetochore def: "A physical cellular phenotype in which the kinetochore is divided into two or more parts." [PomBase:mah] is_a: FYPO:0005646 ! abnormal kinetochore morphology created_by: midori creation_date: 2016-09-06T14:23:27Z [Term] id: FYPO:0005648 name: sister kinetochore dissociation in meiotic metaphase I def: "A physical cellular phenotype in which sister kinetochores separate during the first meiotic nuclear division. Normally sister kinetochores remain together until meiosis II." [PomBase:mah] comment: This term describes the premature separation of paired, intact sister kinetochores. It has a related synonym using "split kinetochores" because that phrase is often used in the literature to describe this phenotype. It should not be confused with the FYPO terms that have "split kinetochore" in the names, because those names refer to cases where a single kinetochore has broken into parts. synonym: "decreased meiosis I sister kinetochore fusion" NARROW [] synonym: "decreased meiotic sister kinetochore association in meiotic metaphase I" EXACT [] synonym: "precocious centromeric dissociation during meiosis I" EXACT [PomBase:vw] synonym: "premature sister kinetochore separation during meiosis I" EXACT [PomBase:mah] synonym: "sister kinetochore separation during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "sister kinetochore separation during meiosis I" EXACT [] synonym: "split kinetochores during meiosis I" RELATED [PomBase:vw] is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2016-09-06T14:25:27Z [Term] id: FYPO:0005649 name: increased duration of protein localization to telomere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the telomere of a chromosome is longer than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to telomere" EXACT [PomBase:mah] synonym: "increased duration of protein localization to chromosome, telomeric region" EXACT [GO:0070198, PomBase:mah] synonym: "increased duration of protein localization to telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to telomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to telomeric region" EXACT [PomBase:vw] synonym: "prolonged protein localization to telomere" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2016-09-06T14:38:58Z [Term] id: FYPO:0005650 name: normal onset of premeiotic DNA replication def: "A cellular process phenotype in which premeiotic DNA replication begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PomBase:mah] synonym: "normal timing of premeiotic DNA replication" RELATED [PomBase:mah] is_a: FYPO:0007277 ! normal cellular process during meiotic cell cycle created_by: midori creation_date: 2016-09-06T14:42:46Z [Term] id: FYPO:0005651 name: abnormal nuclear morphology during meiosis I def: "A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal during the first meiotic nuclear division." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "abnormal nuclear morphology during first meiotic nuclear division" EXACT [GO:0007127] synonym: "deformed nucleus during meiosis I" EXACT [PomBase:vw] synonym: "nuclear morphology defects during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0008242 ! abnormal nuclear morphology during meiotic cell cycle created_by: midori creation_date: 2016-09-06T14:45:30Z [Term] id: FYPO:0005652 name: abnormal spindle morphology during meiosis I def: "A physical cellular phenotype in which the size, shape, or structure of the spindle is abnormal during the first meiotic nuclear division." [PomBase:mah] comment: Note that an abnormal spindle organization process may, but does not necessarily, result in abnormal spindle morphology. synonym: "abnormal spindle morphology during first meiotic nuclear division" EXACT [GO:0007127] is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2016-09-06T14:47:51Z [Term] id: FYPO:0005653 name: increased level of iron ion starvation-induced proteins during glutathione starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced during iron ion starvation measured in a cell is higher than normal when the cell is subject to glutathione starvation." [PMID:25806539, PomBase:mah] synonym: "increased level of iron ion depletion-induced proteins during glutathione starvation" EXACT [PomBase:vw] synonym: "increased level of iron ion deprivation-induced proteins during glutathione starvation" EXACT [PomBase:vw] synonym: "increased level of iron ion starvation-induced proteins during cellular response to glutathione starvation" EXACT [PomBase:mah] synonym: "increased level of iron ion starvation-induced proteins during glutathione starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of iron ion starvation-induced proteins during glutathione starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002010 ! increased level of iron ion starvation-induced proteins created_by: midori creation_date: 2016-09-06T14:52:52Z [Term] id: FYPO:0005654 name: decreased level of iron assimilation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell." [PMID:25806539, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased iron assimilation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of iron assimilation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of iron assimilation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of iron assimilation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of iron assimilation gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2016-09-06T14:55:54Z [Term] id: FYPO:0005655 name: normal level of iron assimilation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is normal (i.e. indistinguishable from wild type). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell." [PMID:25806539, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal iron assimilation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "normal level of iron assimilation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of iron assimilation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of iron assimilation gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2016-09-06T14:56:46Z [Term] id: FYPO:0005656 name: abolished iron ion binding def: "A molecular function phenotype in which iron ion binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished iron binding" EXACT [GO:0005506] synonym: "iron ion binding abolished" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2016-09-06T14:59:49Z [Term] id: FYPO:0005657 name: normal frequency of meiotic crossover associated with gene conversion def: "A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is normal (i.e. indistinguishable from wild type)." [PMID:25414342, PomBase:mah] synonym: "normal levels of meiotic crossover associated with a gene conversion event" EXACT [PMID:25414342] is_a: FYPO:0000488 ! normal meiotic recombination created_by: midori creation_date: 2016-09-06T15:05:46Z [Term] id: FYPO:0005658 name: abnormal frequency of meiotic crossover associated with gene conversion def: "A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is abnormal." [PMID:25414342, PomBase:mah] synonym: "abnormal levels of meiotic crossover associated with a gene conversion event" EXACT [PMID:25414342] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2016-09-06T15:15:38Z [Term] id: FYPO:0005659 name: increased frequency of meiotic crossover associated with gene conversion def: "A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is increased." [PMID:25414342, PomBase:mah] comment: This phenotype potentially reflects a change in the crossover/non-crossover decision pathway. synonym: "increased levels of meiotic crossover associated with a gene conversion event" EXACT [PMID:25414342] is_a: FYPO:0005658 ! abnormal frequency of meiotic crossover associated with gene conversion created_by: midori creation_date: 2016-09-06T15:16:20Z [Term] id: FYPO:0005660 name: decreased frequency of meiotic crossover associated with gene conversion def: "A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is decreased." [PMID:25414342, PomBase:mah] comment: This phenotype potentially reflects a change in the crossover/non-crossover decision pathway. synonym: "decreased levels of meiotic crossover associated with a gene conversion event" EXACT [PMID:25414342] synonym: "reduced frequency of meiotic crossover associated with gene conversion" EXACT [PomBase:mah] is_a: FYPO:0005658 ! abnormal frequency of meiotic crossover associated with gene conversion created_by: midori creation_date: 2016-09-06T15:16:42Z [Term] id: FYPO:0005661 name: increased transcription during nitrogen starvation def: "A cellular process phenotype in which transcription occurs to a greater extent than normal when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). synonym: "increased transcription during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "increased transcription during nitrogen depletion" EXACT [PomBase:vw] synonym: "increased transcription during nitrogen deprivation" EXACT [PomBase:vw] synonym: "increased transcription during nitrogen limitation" EXACT [PomBase:mah] synonym: "increased transcription in response to nitrogen starvation" EXACT [PomBase:mah, PomBase:vw] synonym: "increased transcriptional response to nitrogen starvation" EXACT [PomBase:al] is_a: FYPO:0002875 ! increased transcription created_by: midori creation_date: 2016-09-13T11:35:19Z [Term] id: FYPO:0005662 name: increased transcription from TR box def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more TR boxes occurs to a greater extent than normal." [PMID:7975894, PomBase:mah] synonym: "expression of TR box target genes increased" RELATED [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2016-09-13T11:38:01Z [Term] id: FYPO:0005663 name: abnormal re-entry into mitotic cell cycle after arrest in response to heat shock def: "A cellular process phenotype in which re-entry into the mitotic cell cycle is abnormal after arrest resulting from heat shock." [PMID:19546237, PomBase:mah] synonym: "abnormal re-entry into mitotic cell cycle after arrest in response to heat shock during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal re-entry into mitotic cell cycle after heat shock arrest" EXACT [PomBase:al] synonym: "abnormal re-entry into mitotic cell cycle after heat shock-induced arrest" EXACT [PomBase:mah] is_a: FYPO:0000212 ! abnormal cellular response to heat created_by: midori creation_date: 2016-09-13T11:43:32Z [Term] id: FYPO:0005664 name: viable elongated cell during nitrogen starvation def: "A cell morphology phenotype in which a cell is viable, and becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to nitrogen starvation." [PMID:12399381, PMID:19366728, PomBase:mah] comment: Note that wild-type cells become shorter under nitrogen starvation conditions than under nitrogen-replete conditions, and that mutant cells subjected to nitrogen starvation may have lengths similar to wild type cells under non-starved conditions. Also note that this term is classified as a type of abnormal cell shape, because under a given set of conditions wild-type cells are never seen with the proportions (length:diameter ratio) observed in elongated cells. Small cells, in contrast, have the same proportions as a subset of wild-type cells, and simply do not grow to the full length seen in wild type. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "cdr phenotype" EXACT [PomBase:vw] synonym: "viable elongated cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "viable elongated cell during nitrogen deprivation" EXACT [PomBase:vw] synonym: "viable long cell during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0000998 ! elongated cell during nitrogen starvation relationship: has_part FYPO:0000124 ! viable cell relationship: has_part FYPO:0000998 ! elongated cell during nitrogen starvation created_by: midori creation_date: 2016-09-13T12:05:33Z [Term] id: FYPO:0005665 name: abnormal actin cytoskeleton def: "A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton physical object quality" EXACT [PomBase:mah] is_a: FYPO:0002397 ! abnormal cytoskeleton relationship: output_of FYPO:0004803 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2016-09-13T13:27:08Z [Term] id: FYPO:0005666 name: abnormal actin cytoskeleton during meiosis def: "A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal during one or both meiotic nuclear divisions." [PomBase:mah] comment: Note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton during meiotic nuclear division" EXACT [GO:0140013] synonym: "abnormal actin cytoskeleton physical object quality during meiosis" EXACT [PomBase:mah] is_a: FYPO:0005665 ! abnormal actin cytoskeleton created_by: midori creation_date: 2016-09-13T13:41:02Z [Term] id: FYPO:0005667 name: premature protein localization to nucleus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus begins earlier than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "faster protein localization to nucleus during vegetative growth" RELATED [PomBase:mah] synonym: "premature protein localisation to nucleus during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "premature protein localization to nucleus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2016-09-13T13:52:46Z [Term] id: FYPO:0005668 name: sensitive to cAMP def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cyclic AMP (cAMP). Cells stop growing (and may die) at a concentration of cAMP that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cAMP" EXACT [PomBase:mah] synonym: "sensitive to cAMP during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to cAMP during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to cyclic AMP" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-09-14T16:21:22Z [Term] id: FYPO:0005669 name: obsolete cut with abnormal chromosome segregation during cellular response to hydroxyurea def: "OBSOLETE. A cut phenotype with abnormal chromosome segregation that is observed when a cell is exposed to hydroxyurea. In this type of cut phenotype, a cell undergoes septation despite abnormal chromosome segregation such that the nucleus forms a single mass through which the septum forms." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0003165. synonym: "cut with abnormal chromosome segregation during cellular response to HU" EXACT [PomBase:mah] synonym: "cut with abnormal chromosome segregation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut with abnormal chromosome segregation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "cut with abnormal chromosome segregation in response to hydroxyurea" EXACT [PomBase:mah] synonym: "cut with abnormal mitotic chromosome segregation during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "septation following abnormal chromosome segregation during cellular response to hydroxyurea" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0003165 created_by: midori creation_date: 2016-09-19T14:11:22Z [Term] id: FYPO:0005670 name: obsolete cut with abnormal chromosome segregation during cellular response to methyl methanesulfonate def: "OBSOLETE. A cut phenotype with abnormal chromosome segregation that is observed when a cell is exposed to methyl methanesulfonate. In this type of cut phenotype, a cell undergoes septation despite abnormal chromosome segregation such that the nucleus forms a single mass through which the septum forms." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0003165. synonym: "cut with abnormal chromosome segregation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut with abnormal chromosome segregation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "cut with abnormal chromosome segregation during cellular response to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "cut with abnormal chromosome segregation during cellular response to MMS" EXACT [PomBase:mah] synonym: "cut with abnormal chromosome segregation in response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "cut with abnormal mitotic chromosome segregation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "septation following abnormal chromosome segregation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0003165 created_by: midori creation_date: 2016-09-19T14:11:29Z [Term] id: FYPO:0005671 name: increased septation index during cellular response to methyl methanesulfonate def: "A cell population phenotype in which the septation index is higher than normal in a population that is exposed to methyl methanesulfonate. The septation index is the proportion of the population undergoing septation at any given time." [PomBase:mah, PomBase:vw] synonym: "increased septation index during cellular response to MMS" EXACT [PomBase:mah] synonym: "increased septation index in response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0000650 ! increased septation index created_by: midori creation_date: 2016-09-19T14:21:10Z [Term] id: FYPO:0005672 name: decreased protein localization to nucleus during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during mitosis" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to nucleus during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during mitotic nuclear division" EXACT [GO:0140014] synonym: "reduced protein localization to nucleus during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2016-09-19T14:58:42Z [Term] id: FYPO:0005673 name: decreased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured the cell is lower than normal during a cellular response to methyl methanesulfonate. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased accumulation of ubiquitinated protein in cell during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "decreased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of ubiquitinated protein in cell during cellular response to MMS" EXACT [PomBase:mah] synonym: "decreased level of ubiquitylated protein in cell during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "decreased ubiquitinated protein level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0003143 ! decreased protein level during cellular response to methyl methanesulfonate is_a: FYPO:0005226 ! decreased level of ubiquitinated protein in cell created_by: midori creation_date: 2016-09-21T15:28:58Z [Term] id: FYPO:0005674 name: increased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured the cell is higher than normal during a cellular response to methyl methanesulfonate. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased accumulation of ubiquitinated protein in cell during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "increased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of ubiquitinated protein in cell during cellular response to MMS" EXACT [PomBase:mah] synonym: "increased level of ubiquitylated protein in cell during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "increased ubiquitinated protein level during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002774 ! increased level of ubiquitinated protein in cell during vegetative growth is_a: FYPO:0005333 ! increased protein level during cellular response to methyl methanesulfonate created_by: midori creation_date: 2016-09-21T15:31:14Z [Term] id: FYPO:0005675 name: normal protein deubiquitination following cellular response to methyl methanesulfonate during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) after cells have been exposed to methyl methanesulfonate." [PMID:27151298, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein deubiquitination during cellular response to methyl methanesulfonate" RELATED [GO:0000209, PomBase:mah] synonym: "normal protein deubiquitination following cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein deubiquitination following cellular response to MMS" EXACT [PomBase:mah] synonym: "normal protein deubiquitylation following cellular response to methyl methanesulfonate" EXACT [GO:0016579, PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2016-09-21T15:45:09Z [Term] id: FYPO:0005676 name: abolished protein deubiquitination following cellular response to methyl methanesulfonate during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deubiquitination of one or more specific proteins, or of specific protein sites, does not occur after cells have been exposed to methyl methanesulfonate." [PMID:27151298, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein deubiquitination during cellular response to methyl methanesulfonate" RELATED [PomBase:mah] synonym: "abolished protein deubiquitination following cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein deubiquitination following cellular response to MMS" EXACT [PomBase:mah] synonym: "abolished protein deubiquitylation following cellular response to methyl methanesulfonate" EXACT [GO:0016579, PomBase:mah] synonym: "protein deubiquitination following cellular response to methyl methanesulfonate abolished" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0005377 ! abolished proteolysis during vegetative growth created_by: midori creation_date: 2016-09-21T15:50:13Z [Term] id: FYPO:0005677 name: decreased number of Rad52 foci during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is lower than normal during S phase of the mitotic cell cycle." [PMID:27151298, PomBase:mah] synonym: "decreased number of Rad22 foci during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased number of Rad52 foci during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased number of Rad52 foci during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced number of Rad52 foci during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0004516 ! decreased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2016-09-21T16:01:41Z [Term] id: FYPO:0005678 name: ubiquitinated protein absent from cell during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured in a cell is too low to detect. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ubiquitinated protein absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "ubiquitylated protein absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "undetectable cellular ubiquitinated protein level during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0001984 ! protein absent from cell during vegetative growth created_by: midori creation_date: 2016-09-21T16:03:57Z [Term] id: FYPO:0005679 name: decreased protein deubiquitination following cellular response to hydroxyurea during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deubiquitination of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal after cells have been exposed to hydroxyurea." [PMID:27151298, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein deubiquitination during cellular response to hydroxyurea" RELATED [GO:0000209, PomBase:mah] synonym: "decreased protein deubiquitination following cellular response to HU" EXACT [PomBase:mah] synonym: "decreased protein deubiquitination following cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein deubiquitylation following cellular response to hydroxyurea" EXACT [GO:0016579, PomBase:mah] synonym: "reduced protein deubiquitination following cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0005443 ! decreased proteolysis during vegetative growth created_by: midori creation_date: 2016-09-21T16:06:20Z [Term] id: FYPO:0005680 name: normal number of Rad52 foci during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle." [PMID:27151298, PomBase:mah] synonym: "normal number of Rad22 foci during mitotic S phase" EXACT [PomBase:mah] synonym: "normal number of Rad52 foci during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal number of Rad52 foci during S phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0007328 ! normal number of Rad52 foci during vegetative growth created_by: midori creation_date: 2016-09-21T16:08:55Z [Term] id: FYPO:0005681 name: decreased microtubule polymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers, occurs to a lesser extent than normal." [GO:0046785, PomBase:mah] synonym: "decreased microtubule growth" EXACT [PomBase:vw] synonym: "decreased microtubule polymerisation" EXACT [PomBase:mah] synonym: "decreased microtubule polymerization" RELATED [PomBase:mah] synonym: "decreased microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased microtubule polymerization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced microtubule polymerization" EXACT [PomBase:mah] is_a: FYPO:0004614 ! abnormal microtubule polymerization during vegetative growth created_by: midori creation_date: 2016-09-26T11:07:22Z [Term] id: FYPO:0005682 name: decreased microtubule depolymerization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers, occurs to a lesser extent than normal." [GO:0007019, PomBase:mah] synonym: "decreased microtubule catastrophe during vegetative growth" RELATED [PomBase:mah] synonym: "decreased microtubule depolymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased microtubule shrinkage during vegetative growth" RELATED [PomBase:vw] synonym: "reduced microtubule depolymerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth created_by: midori creation_date: 2016-09-26T11:07:44Z [Term] id: FYPO:0005683 name: increased duration of mitotic prophase def: "A cellular process phenotype in which the duration of progression through prophase of mitosis is longer than normal." [PomBase:mah] synonym: "delayed mitotic prophase progression" RELATED [PomBase:mah] synonym: "increased duration of mitotic prophase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic prophase progression" EXACT [PomBase:mah] synonym: "increased duration of prophase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "prolonged mitotic prophase" EXACT [PomBase:mah] is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-09-26T11:32:50Z [Term] id: FYPO:0005684 name: increased duration of mitotic prometaphase def: "A cellular process phenotype in which the duration of progression through prometaphase of mitosis is longer than normal." [PomBase:mah] synonym: "delayed mitotic prometaphase progression" RELATED [PomBase:mah] synonym: "increased duration of mitotic prometaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic prometaphase progression" EXACT [PomBase:mah] synonym: "increased duration of prometaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "prolonged mitotic prometaphase" EXACT [PomBase:mah] is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-09-26T11:34:02Z [Term] id: FYPO:0005685 name: decreased RNA level during cellular response to cadmium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to cadmium ions is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to cadmium ion" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to cadmium" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to cadmium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to cadmium ion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to cadmium ion" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to cadmium ion" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2016-09-26T11:39:18Z [Term] id: FYPO:0005686 name: microtubule bundles present in decreased numbers during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer microtubule bundles than normal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "decreased interphase microtubule arrays" RELATED [PomBase:vw] synonym: "decreased level of MT bundles during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased microtubule bundling during mitotic interphase" RELATED [PomBase:vw] synonym: "microtubule arrays present in decreased numbers during mitotic interphase" RELATED [PomBase:vw] synonym: "microtubule bundles present in decreased numbers during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "microtubule bundles present in decreased numbers during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule bundles present in reduced numbers during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-09-26T12:05:27Z [Term] id: FYPO:0005687 name: eMTOC absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable equatorial microtubule organizing center (eMTOC)." [PomBase:mah] synonym: "absent eMTOC" EXACT [PomBase:mah] synonym: "eMTOC absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "eMTOC absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "equatorial microtubule organizing center absent from cell" EXACT [PomBase:mah] is_a: FYPO:0004315 ! abnormal microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2016-09-26T13:48:48Z [Term] id: FYPO:0005688 name: normal astral microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, and morphology of astral microtubules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal astral microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal astral microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "normal cytoplasmic astral microtubules" EXACT [PomBase:vw] is_a: FYPO:0001976 ! normal cytoplasmic microtubules during vegetative growth created_by: midori creation_date: 2016-09-26T13:55:02Z [Term] id: FYPO:0005689 name: inviable binucleate aseptate cell with mitotic cell cycle arrest before cell separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested before cell separation takes place." [PomBase:mah] comment: This phenotype may indicate that the cytokinesis after mitosis checkpoint is activated. synonym: "inviable binucleate aseptate cell with mitotic cell cycle arrest before cell separation during vegetative growth" EXACT [PomBase:mah] synonym: "inviable binucleate aseptate cell with mitotic cell cycle arrest before cytokinetic cell separation" EXACT [PomBase:mah] synonym: "inviable binucleate cell with mitotic cell cycle arrest before septation" RELATED [PomBase:mah] synonym: "inviable cell with nuclear division arrest without septation (normal cell length)" EXACT [PomBase:vw] synonym: "lethal; binucleate aseptate cell with mitotic cell cycle arrest before cell separation" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest before cell separation with inviable binucleate aseptate cell" EXACT [PomBase:vw] is_a: FYPO:0002888 ! mitotic cell cycle arrest before cell separation is_a: FYPO:0004106 ! inviable multinucleate aseptate vegetative cell is_a: FYPO:0004562 ! binucleate aseptate vegetative cell relationship: has_part FYPO:0002888 ! mitotic cell cycle arrest before cell separation created_by: midori creation_date: 2016-09-26T14:11:59Z [Term] id: FYPO:0005690 name: abnormal eMTOC assembly def: "A cellular process phenotype in which equatorial microtubule organizing center (eMTOC) assembly is abnormal. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center." [GO:1904185, PomBase:mah] synonym: "abnormal eMTOC assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal eMTOC assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal eMTOC formation" EXACT [PomBase:mah] synonym: "abnormal equatorial microtubule organizing center assembly" EXACT [PomBase:mah] synonym: "abnormal equatorial microtubule organizing center formation" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2016-09-26T14:43:58Z [Term] id: FYPO:0005691 name: decreased spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body (SPB) moves rapidly back and forth to a lower extent and over a smaller area than normal, causing decreased chromosome movement. Normally, SPB oscillation occurs during mitotic interphase (as well as prophase) but is restricted to a small space." [PMID:12390246, PMID:19001497, PomBase:mah] synonym: "decreased mitotic SPB oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased spindle pole body-led chromosome movement during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0005348 ! abnormal spindle pole body-led chromosome movement during mitotic interphase is_a: FYPO:0005462 ! decreased microtubule-based movement during vegetative growth created_by: midori creation_date: 2016-09-28T11:10:58Z [Term] id: FYPO:0005692 name: abnormal microtubule nucleation during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) is abnormal." [PMID:19001497, PomBase:mah] synonym: "abnormal microtubule nucleation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "microtubule nucleation defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth is_a: FYPO:0007484 ! abnormal microtubule nucleation created_by: midori creation_date: 2016-09-28T11:29:34Z [Term] id: FYPO:0005693 name: abolished cytoplasmic microtubule nucleation def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from one or more microtubule organizing centers (MTOCs) is does not occur." [PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic microtubule nucleation abolished" EXACT [PomBase:mah] is_a: FYPO:0005692 ! abnormal microtubule nucleation during vegetative growth created_by: midori creation_date: 2016-09-28T11:47:43Z [Term] id: FYPO:0005694 name: decreased interphase microtubule nucleation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules occurs to a lower extent than normal during interphase of the mitotic cell cycle." [PMID:19001497, PomBase:mah] synonym: "decreased cytoplasmic microtubule nucleation during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased interphase cytoplasmic microtubule nucleation" EXACT [PomBase:mah] synonym: "decreased interphase microtubule nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule nucleation during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased microtubule nucleation during mitotic interphase" EXACT [PomBase:mah] synonym: "reduced interphase microtubule nucleation" EXACT [PomBase:mah] is_a: FYPO:0006335 ! decreased microtubule nucleation during vegetative growth created_by: midori creation_date: 2016-09-28T13:40:21Z [Term] id: FYPO:0005695 name: abolished astral microtubule nucleation during mitosis def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of astral microtubules from the spindle pole body does not occur during mitosis." [PMID:19001497, PomBase:mah] synonym: "abolished astral microtubule nucleation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished astral microtubule nucleation during mitotic nuclear division" EXACT [GO:0140014] synonym: "astral microtubule nucleation during mitosis abolished" EXACT [PomBase:mah] is_a: FYPO:0005693 ! abolished cytoplasmic microtubule nucleation created_by: midori creation_date: 2016-09-28T14:17:36Z [Term] id: FYPO:0005696 name: abolished cytoplasmic microtubule nucleation from iMTOC def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the interphase microtubule organizing center does not occur. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB)." [PMID:19001497, PomBase:mah] synonym: "abolished cytoplasmic interphase microtubule nucleation from iMTOC" EXACT [PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation from iMTOC during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished interphase cytoplasmic microtubule nucleation from iMTOC" EXACT [PomBase:mah] synonym: "abolished interphase microtubule nucleation from iMTOC during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished interphase microtubule nucleation from iMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "abolished microtubule nucleation from interphase microtubule organizing center" EXACT [PomBase:mah] synonym: "abolished microtubule nucleation from interphase microtubule organizing centre" EXACT [PomBase:mah] synonym: "cytoplasmic microtubule nucleation from iMTOC abolished" EXACT [PomBase:mah] is_a: FYPO:0004766 ! abolished cytoplasmic interphase microtubule nucleation created_by: midori creation_date: 2016-09-28T14:22:34Z [Term] id: FYPO:0005697 name: abolished cytoplasmic interphase microtubule nucleation from spindle pole body def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the spindle pole body (SPB) does not occur during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the SPB." [PMID:19001497, PomBase:mah] synonym: "abolished cytoplasmic interphase microtubule nucleation from SPB" EXACT [PomBase:mah] synonym: "abolished cytoplasmic interphase microtubule nucleation from spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation by spindle pole body" EXACT [GO:0051417] synonym: "abolished cytoplasmic microtubule nucleation from spindle pole body during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation from spindle pole body during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished interphase microtubule nucleation from spindle pole body" EXACT [PomBase:vw] synonym: "cytoplasmic microtubule nucleation from spindle pole body abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0004766 ! abolished cytoplasmic interphase microtubule nucleation created_by: midori creation_date: 2016-09-28T14:26:18Z [Term] id: FYPO:0005698 name: abolished microtubule nucleation from eMTOC def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from the equatorial microtubule organizing center does not occur." [PMID:19001497, PomBase:mah] synonym: "abolished cytoplasmic microtubule nucleation from eMTOC" EXACT [PomBase:mah] synonym: "abolished microtubule nucleation from eMTOC during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished microtubule nucleation from eMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "abolished microtubule nucleation from equatorial microtubule organizing center" EXACT [PomBase:mah] synonym: "abolished microtubule nucleation from equatorial microtubule organizing centre" EXACT [PomBase:mah] synonym: "microtubule nucleation from eMTOC abolished" EXACT [PomBase:mah] is_a: FYPO:0005693 ! abolished cytoplasmic microtubule nucleation relationship: has_output FYPO:0004619 ! cytoplasmic microtubules nucleated from eMTOC absent from cell created_by: midori creation_date: 2016-09-28T14:33:36Z [Term] id: FYPO:0005699 name: normal interphase microtubule nucleation from spindle pole body def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the spindle pole body (SPB) normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PMID:19001497, PomBase:mah] synonym: "normal cytoplasmic microtubule nucleation from SPB during mitotic interphase" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule nucleation from spindle pole body during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule nucleation from spindle pole body during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule nucleation from spindle pole body during mitotic interphase" EXACT [PomBase:mah] synonym: "normal interphase cytoplasmic microtubule nucleation from spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0003326 ! normal interphase microtubule nucleation created_by: midori creation_date: 2016-09-28T14:40:08Z [Term] id: FYPO:0005700 name: abolished protein localization to eMTOC def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the equatorial microtubule organizing center (eMTOC) does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to eMTOC" EXACT [PomBase:mah] synonym: "abolished protein localization to eMTOC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to eMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to equatorial microtubule organizing center" EXACT [PomBase:mah] synonym: "protein absent from eMTOC" RELATED [PomBase:mah] synonym: "protein localization to eMTOC abolished" EXACT [PomBase:mah] is_a: FYPO:0000934 ! abolished protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0005702 ! abnormal protein localization to microtubule organizing center created_by: midori creation_date: 2016-09-28T14:49:00Z [Term] id: FYPO:0005701 name: abolished protein localization to iMTOC def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the interphase microtubule organizing center does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to iMTOC" EXACT [PomBase:mah] synonym: "abolished protein localization to iMTOC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to iMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to interphase microtubule organizing center" EXACT [PomBase:mah] synonym: "protein absent from iMTOC" RELATED [PomBase:mah] synonym: "protein localization to iMTOC abolished" EXACT [PomBase:mah] is_a: FYPO:0000934 ! abolished protein localization to microtubule cytoskeleton during vegetative growth is_a: FYPO:0005702 ! abnormal protein localization to microtubule organizing center created_by: midori creation_date: 2016-09-28T14:50:10Z [Term] id: FYPO:0005702 name: abnormal protein localization to microtubule organizing center def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubule organizing centers is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to microtubule organizing centre" EXACT [PomBase:mah] synonym: "abnormal protein localization to microtubule organizing center during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to microtubule organizing center during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2016-09-28T14:51:05Z [Term] id: FYPO:0005703 name: decreased rate of microtubule polymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, occurs at a lower rate, or speed, than normal." [GO:0046785, PomBase:mah] synonym: "decreased microtubule plus end growth rate" EXACT [PomBase:vw] synonym: "decreased microtubule polymerization rate" EXACT [PomBase:mah] synonym: "decreased rate of microtubule growth" EXACT [PomBase:vw] synonym: "decreased rate of microtubule polymerisation" EXACT [PomBase:mah] synonym: "decreased rate of microtubule polymerisation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced rate of microtubule polymerization" EXACT [PomBase:mah] is_a: FYPO:0007955 ! abnormal rate of microtubule polymerization during vegetative growth created_by: midori creation_date: 2016-09-28T14:58:46Z [Term] id: FYPO:0005704 name: loss of viability following cellular response to hydroxyurea def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to hydroxyurea." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown in the presence of hydroxyurea, and then the number of cells viable enough to form a colony upon hydroxyurea removal is measured and compared to wild type. synonym: "decreased viability following cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "loss of cell population viability following cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "loss of viability following cellular response to HU" EXACT [PomBase:mah] synonym: "loss of viability following HU exposure" EXACT [PomBase:mah] synonym: "reduced viability following cellular response to hydroxyurea" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2016-10-24T12:00:31Z [Term] id: FYPO:0005705 name: loss of viability following cellular response to UV def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to ultraviolet light." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown with exposure to UV light, and then the number of cells viable enough to form a colony upon return to absence of UV is measured and compared to wild type. synonym: "decreased viability following cellular response to UV" EXACT [PomBase:mah] synonym: "loss of cell population viability following cellular response to UV" EXACT [PomBase:mah] synonym: "loss of viability following cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "loss of viability following UV exposure" EXACT [PomBase:mah] synonym: "reduced viability following cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2016-10-24T12:00:42Z [Term] id: FYPO:0005706 name: increased duration of mitotic anaphase B def: "A cellular process phenotype in which the duration of progression through anaphase B of mitosis is longer than normal. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart." [GO:0000092, PomBase:mah] synonym: "delayed mitotic anaphase B progression" RELATED [PomBase:mah] synonym: "increased duration of anaphase B during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase B progression" EXACT [PomBase:mah] synonym: "prolonged mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0000618 ! increased duration of mitotic anaphase created_by: midori creation_date: 2016-10-24T12:47:24Z [Term] id: FYPO:0005707 name: normal protein localization to eMTOC def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the equatorial microtubule organizing center (eMTOC) is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to eMTOC" EXACT [PomBase:mah] synonym: "normal protein localization to eMTOC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to eMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to equatorial microtubule organizing center" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2016-10-24T13:19:38Z [Term] id: FYPO:0005708 name: normal protein localization to iMTOC def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the interphase microtubule organizing center (iMTOC) is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to iMTOC" EXACT [PomBase:mah] synonym: "normal protein localization to iMTOC during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to iMTOC during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to interphase microtubule organizing center" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2016-10-24T13:22:15Z [Term] id: FYPO:0005709 name: normal protein localization to mitotic spindle pole body during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle pole body during mitosis" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic SPB during mitosis" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle pole body during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein localization to mitotic spindle pole body during mitotic nuclear division" EXACT [GO:0140014] synonym: "normal protein localization to spindle pole body during mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth is_a: FYPO:0002967 ! normal protein localization to mitotic spindle pole body created_by: midori creation_date: 2016-10-24T13:27:12Z [Term] id: FYPO:0005710 name: abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with mitotic cell cycle arrest def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome, followed by cell cycle arrest." [PMID:7774573, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete re-replication, with mitotic cell cycle arrest" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with cell cycle arrest, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with mitotic cell cycle arrest with replicated DNA" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with mitotic cell cycle arrest, during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation resulting in complete rereplication, with mitotic cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0000444 ! abnormal mitotic cell cycle arrest with replicated DNA is_a: FYPO:0001425 ! abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication relationship: has_part FYPO:0000444 ! abnormal mitotic cell cycle arrest with replicated DNA created_by: midori creation_date: 2016-10-24T13:49:41Z [Term] id: FYPO:0005711 name: decreased cyclin B1-CDK1 complex level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer protein complexes consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1) than normal." [PMID:8087848, PomBase:mah] synonym: "cyclin B1-CDK1 complexes present at decreased level" EXACT [PomBase:mah] synonym: "decreased cyclin B1-CDK1 complex level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cyclin B1-CDK1 complex level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cyclin B1-CDK1 complex level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2016-10-24T13:59:15Z [Term] id: FYPO:0005712 name: sensitive to Cutin-1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Cutin-1 (N-carbamoyl-2-(triphenyl-lambda-5-phosphanylidene)acetamide). Cells stop growing (and may die) at a concentration of Cutin-1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Cutin-1" EXACT [PomBase:mah] synonym: "sensitive to Cutin-1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to Cutin-1 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to N-carbamoyl-2-(triphenyl-lambda-5-phosphanylidene)acetamide" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-10-24T14:33:09Z [Term] id: FYPO:0005713 name: abolished cytokinesis checkpoint def: "A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic cytokinesis checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the cytokinesis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle." [GO:0044878, PomBase:mah] synonym: "abolished cytokinesis checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished cytokinesis checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic cytokinesis checkpoint" EXACT [PomBase:mah] is_a: FYPO:0003830 ! abnormal cytokinesis checkpoint created_by: midori creation_date: 2016-10-31T13:42:47Z [Term] id: FYPO:0005714 name: premature protein localization to nucleolus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus begins earlier than normal." [PMID:17538026, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to nucleolus" EXACT [PomBase:mah] synonym: "precocious protein localization to nucleolus" RELATED [PATO:0000694] synonym: "premature protein localisation to nucleolus" EXACT [PomBase:mah] synonym: "premature protein localization to nucleolus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature protein localization to nucleolus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003687 ! abnormal protein localization to nucleolus created_by: midori creation_date: 2016-10-31T13:58:43Z [Term] id: FYPO:0005715 name: delayed activation of protein kinase activity during mitosis def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which activation of an inactive protein kinase activity begins later than normal during mitosis." [PMID:8978687, PomBase:mah] synonym: "delayed activation of protein kinase activity during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed activation of protein kinase activity during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed activation of protein kinase activity during mitotic M phase" RELATED [PomBase:mah] synonym: "delayed activation of protein kinase activity during mitotic M-phase" RELATED [PomBase:vw] synonym: "delayed onset of activation of protein kinase activity during mitosis" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2016-10-31T14:11:45Z [Term] id: FYPO:0005716 name: delayed negative regulation of protein kinase activity during mitosis def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of a protein kinase activity begins later than normal during mitosis." [PMID:8978687, PomBase:mah] synonym: "delayed inactivation of protein kinase activity during mitosis" NARROW [PomBase:mah] synonym: "delayed inactivation of protein kinase activity during mitosis during mitotic M-phase" RELATED [PomBase:vw] synonym: "delayed negative regulation of protein kinase activity during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed negative regulation of protein kinase activity during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed negative regulation of protein kinase activity during mitotic M phase" RELATED [PomBase:mah] synonym: "delayed onset of negative regulation of protein kinase activity during mitosis" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2016-10-31T14:27:47Z [Term] id: FYPO:0005717 name: normal protein kinase activity during mitosis def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] synonym: "normal protein kinase activity during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein kinase activity during mitotic M-phase" RELATED [PomBase:vw] is_a: FYPO:0003075 ! normal protein kinase activity created_by: midori creation_date: 2016-10-31T14:33:45Z [Term] id: FYPO:0005718 name: decreased protein kinase activity during mitosis def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during mitosis." [PomBase:mah] synonym: "decreased protein kinase activity during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein kinase activity during mitotic M-phase" RELATED [PomBase:vw] synonym: "reduced protein kinase activity during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: midori creation_date: 2016-10-31T14:35:14Z [Term] id: FYPO:0005719 name: abolished mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome recapture does not occur during metaphase of mitosis. Chromosome recapture is the reattachment of chromosomes which have become detached from the spindle." [GO:1990942, PMID:17881496, PomBase:mah] synonym: "abolished chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "abolished kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "abolished mitotic kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "abolished mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic metaphase chromosome retrieval to SPB" EXACT [PomBase:mah] synonym: "abolished mitotic metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "abolished mitotic sister kinetochore recapture" EXACT [GO:1990942] synonym: "mitotic metaphase chromosome recapture abolished" EXACT [PomBase:mah] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2016-11-02T12:02:32Z [Term] id: FYPO:0005720 name: normal mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome recapture is normal (i.e. indistinguishable from wild type) during metaphase of mitosis. Chromosome recapture is the reattachment of chromosomes which have become detached from the spindle." [GO:1990942, PMID:17881496, PomBase:mah] synonym: "normal chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "normal mitotic kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "normal mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic metaphase chromosome retrieval to SPB" EXACT [PomBase:mah] synonym: "normal mitotic metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "normal mitotic sister kinetochore recapture" EXACT [GO:1990942] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2016-11-02T12:05:11Z [Term] id: FYPO:0005721 name: curved mitotic spindle during anaphase B def: "A spindle phenotype in which the mitotic spindle is curved (i.e. follows a smooth bend rather than a straight line) during anaphase B." [PMID:15147872, PomBase:mah] synonym: "curved bipolar mitotic spindle during anaphase B" EXACT [PomBase:vw] synonym: "curved mitotic spindle during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "curved mitotic spindles during anaphase B" EXACT [PomBase:mah] synonym: "curved spindle during anaphase B of mitosis" EXACT [PomBase:mah] synonym: "curved spindle during mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2016-11-02T12:14:07Z [Term] id: FYPO:0005722 name: mitotic spindle collapse during anaphase B elongation def: "A cell phenotype in which a mitotic spindle assembles and begins to elongate, but becomes curved during anaphase B and eventually collapses. The spindle pole bodies separate, but often become spatially closer together as the spindle elongates and curves." [PMID:15147872, PomBase:mah, PomBase:vw] synonym: "broken mitotic spindle during anaphase B elongation" RELATED [PomBase:vw] synonym: "mitotic spindle breakage during anaphase B elongation" EXACT [PomBase:vw] synonym: "mitotic spindle collapse during elongation during anaphase B" EXACT [PomBase:mah] synonym: "mitotic spindle curvature and collapse during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0006475 ! mitotic spindle collapse created_by: midori creation_date: 2016-11-02T12:22:59Z [Term] id: FYPO:0005723 name: abnormal protein methyltransferase activity def: "A molecular function phenotype in which the observed rate of protein methyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-11-02T13:14:41Z [Term] id: FYPO:0005724 name: increased protein methyltransferase activity def: "A molecular function phenotype in which the observed rate of protein methyltransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0005723 ! abnormal protein methyltransferase activity created_by: midori creation_date: 2016-11-02T13:14:53Z [Term] id: FYPO:0005725 name: decreased protein methyltransferase activity def: "A molecular function phenotype in which the observed rate of protein methyltransferase activity is decreased." [PomBase:mah] synonym: "reduced protein methyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005723 ! abnormal protein methyltransferase activity created_by: midori creation_date: 2016-11-02T13:14:53Z [Term] id: FYPO:0005726 name: abolished deactivation of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint does not occur. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PMID:19592249, PMID:21664573, PomBase:mah, PomBase:vw] comment: The difference between this term and constitutive activation of mitotic spindle assembly checkpoint (FYPO:000) is that this term describes cells in which the checkpoint is not active at first, but once activated the checkpoint is not deactivated, whereas FYPO:0007 describes cells in which the checkpoint is always active, i.e. the checkpoint is never observed to be "off". Checkpoint activation in a mutant usually implies that the mutation is causing problems that the checkpoint detects. synonym: "abolished deactivation of mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "abolished mitotic spindle assembly checkpoint deactivation" EXACT [GO:1902426] synonym: "abolished mitotic spindle assembly checkpoint silencing" EXACT [GO:1902426] synonym: "deactivation of mitotic spindle assembly checkpoint abolished" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint created_by: midori creation_date: 2016-11-02T13:30:06Z [Term] id: FYPO:0005727 name: decreased rate of deactivation of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint occurs more slowly than normal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PMID:19592249, PMID:21664573, PomBase:mah, PomBase:vw] comment: Checkpoint activation in a mutant usually implies that the mutation is causing problems that the checkpoint detects. synonym: "decreased rate of deactivation of mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "decreased rate of mitotic spindle assembly checkpoint deactivation" EXACT [GO:1902426] synonym: "decreased rate of mitotic spindle assembly checkpoint silencing" EXACT [GO:1902426] synonym: "delayed inactivation of the mitotic SAC" EXACT [] synonym: "delayed inactivation of the mitotic spindle assembly checkpoint" EXACT [] synonym: "delayed inactivation of the SAC" BROAD [] synonym: "reduced rate of deactivation of mitotic spindle assembly checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint created_by: midori creation_date: 2016-11-02T13:49:32Z [Term] id: FYPO:0005728 name: normal deactivation of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint is normal (i.e. indistinguishable from wild type. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PMID:19592249, PMID:21664573, PomBase:mah, PomBase:vw] comment: Checkpoint activation in a mutant usually implies that the mutation is causing problems that the checkpoint detects. synonym: "normal deactivation of mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "normal mitotic spindle assembly checkpoint deactivation" EXACT [GO:1902426] synonym: "normal mitotic spindle assembly checkpoint silencing" EXACT [GO:1902426] is_a: FYPO:0003762 ! normal mitotic spindle assembly checkpoint created_by: midori creation_date: 2016-11-02T13:49:38Z [Term] id: FYPO:0005729 name: increased cellular ferrichrome level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more ferrichromes measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular ferrichrome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular ferrichrome level during vegetative growth" EXACT [PomBase:mah] synonym: "increased ferrichrome accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-11-02T14:01:33Z [Term] id: FYPO:0005730 name: abnormal arginase activity def: "A molecular function phenotype in which the observed rate of arginase activity is abnormal." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'abnormal cellular respiration' (FYPO:0000078). is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-11-02T14:03:19Z [Term] id: FYPO:0005731 name: decreased arginase activity def: "A molecular function phenotype in which the observed rate of arginase activity is decreased." [PomBase:mah] comment: Also consider using the cellular process phenotype term 'decreased cellular respiration' (FYPO:0000342). synonym: "reduced arginase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005730 ! abnormal arginase activity created_by: midori creation_date: 2016-11-02T14:03:31Z [Term] id: FYPO:0005732 name: abolished arginase activity def: "A molecular function phenotype in which arginase activity is absent." [PomBase:mah] synonym: "arginase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0005730 ! abnormal arginase activity created_by: midori creation_date: 2016-11-02T14:03:31Z [Term] id: FYPO:0005733 name: increased glutamate-ammonia ligase activity during cellular response to iron ion starvation def: "A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is increased during a cellular response to iron ion starvation." [PMID:20435771, PomBase:mah] synonym: "increased glutamate-ammonia ligase activity during iron ion starvation" EXACT [PomBase:mah] synonym: "increased glutamine synthetase activity during cellular response to iron ion starvation" EXACT [GO:0004356, PomBase:mah] synonym: "increased glutamylhydroxamic synthetase activity during cellular response to iron ion starvation" EXACT [GO:0004356] synonym: "increased GS activity during cellular response to iron ion starvation" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0002270 ! increased glutamate-ammonia ligase activity created_by: midori creation_date: 2016-11-02T14:06:46Z [Term] id: FYPO:0005734 name: decreased glutamate dehydrogenase (NADP+) activity during cellular response to iron ion starvation def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is decreased during a cellular response to iron ion starvation." [PMID:20435771, PomBase:mah] synonym: "decreased glutamate dehydrogenase (NADP+) activity during iron ion starvation" EXACT [PomBase:mah] synonym: "decreased NAD(P)H-dependent glutamate dehydrogenase activity during cellular response to iron ion starvation" EXACT [GO:0004354] synonym: "decreased NADP-GDH activity during cellular response to iron ion starvation" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000983 ! decreased glutamate dehydrogenase (NADP+) activity created_by: midori creation_date: 2016-11-02T14:08:53Z [Term] id: FYPO:0005735 name: increased protein localization to kinetochore during mitotic M phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is increased during mitotic M-phase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "increased protein localization to kinetochore during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein localization to kinetochore during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0003003 ! increased protein localization to kinetochore during vegetative growth is_a: FYPO:0008164 ! abnormal protein localization to kinetochore during mitotic M phase created_by: midori creation_date: 2016-11-02T14:13:17Z [Term] id: FYPO:0005736 name: decreased prospore membrane formation def: "A cellular process phenotype in which prospore membrane formation is decreased." [PMID:27630265, PomBase:mah] synonym: "decreased ascospore-type prospore membrane assembly" EXACT [GO:0032120, PomBase:mah] synonym: "decreased forespore membrane formation" EXACT [GO:0032120, PomBase:mah] synonym: "reduced prospore membrane formation" EXACT [PomBase:mah] is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2016-11-02T14:16:16Z [Term] id: FYPO:0005737 name: delayed onset of prospore membrane formation def: "A cellular process phenotype in which prospore membrane formation begins later than normal." [PMID:27630265, PomBase:mah] synonym: "delayed onset of ascospore-type prospore membrane assembly" EXACT [GO:0032120, PomBase:mah] synonym: "delayed onset of forespore membrane formation" EXACT [GO:0032120, PomBase:mah] synonym: "delayed prospore membrane formation" EXACT [PomBase:mah] is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2016-11-02T14:17:15Z [Term] id: FYPO:0005738 name: abolished histone H3-S10 phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished histone H3 phosphorylation at S10 during vegetative growth" EXACT [GO:0043987] synonym: "abolished histone H3-S10 phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3S10 phosphorylation during vegetative growth" EXACT [GO:0043987] synonym: "histone H3-S10 phosphorylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-S10 phosphorylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002599 ! abnormal histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2016-11-02T14:20:16Z [Term] id: FYPO:0005739 name: complete but unequal mitotic sister chromatid segregation with unseparated chromosomes def: "A cellular process phenotype in which mitotic sister chromatid segregation results in the division of chromosomes into two distinct unequal masses containing unseparated sister chromatids, located at or near the ends of an elongated mitotic spindle." [PMID:11792803, PomBase:mah, PomBase:vw] is_a: FYPO:0001270 ! complete but unequal mitotic sister chromatid segregation created_by: midori creation_date: 2016-11-02T14:24:44Z [Term] id: FYPO:0005740 name: normal transcription during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to heat. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal global transcription during vegetative growth in response to heat stress" EXACT [PomBase:vw] synonym: "normal transcription during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription during cellular response to heat stress" EXACT [GO:0034605] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2016-11-02T14:27:11Z [Term] id: FYPO:0005741 name: abnormal invertase activity def: "A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is abnormal." [PomBase:mah] comment: Secreted invertase activity is usually measured. synonym: "abnormal beta-fructofuranosidase activity" EXACT [GO:0004564] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-11-02T14:58:42Z [Term] id: FYPO:0005742 name: decreased invertase activity during glucose starvation def: "A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is decreased under conditions of glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased beta-fructofuranosidase activity during glucose starvation" EXACT [GO:0004564] synonym: "decreased invertase activity during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "decreased invertase activity during glucose depletion" EXACT [PomBase:mah] synonym: "decreased invertase activity during glucose deprivation" EXACT [PomBase:mah] synonym: "decreased invertase activity during glucose limitation" RELATED [PomBase:mah] synonym: "reduced invertase activity during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005741 ! abnormal invertase activity created_by: midori creation_date: 2016-11-02T14:58:48Z [Term] id: FYPO:0005743 name: normal invertase activity during glucose starvation def: "A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal beta-fructofuranosidase activity during glucose starvation" EXACT [GO:0004564] synonym: "normal invertase activity during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "normal invertase activity during glucose depletion" EXACT [PomBase:mah] synonym: "normal invertase activity during glucose deprivation" EXACT [PomBase:mah] synonym: "normal invertase activity during glucose limitation" RELATED [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2016-11-02T15:03:30Z [Term] id: FYPO:0005744 name: abnormal protein transport def: "A cellular process phenotype in which protein transport is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0001370 ! abnormal protein localization is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2016-11-02T15:14:17Z [Term] id: FYPO:0005745 name: abnormal protein export from nucleus def: "A transport phenotype in which the export of protein from the nucleus is abnormal. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: Encompasses both export of proteins normally retained in the nucleus and nuclear retention of normally exported proteins. We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0005744 ! abnormal protein transport created_by: midori creation_date: 2016-11-02T15:15:48Z [Term] id: FYPO:0005746 name: decreased protein export from nucleus during glucose starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein export from nucleus is decreased when the cell is subject to glucose starvation. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased protein export from nucleus during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "decreased protein export from nucleus during glucose depletion" EXACT [PomBase:mah] synonym: "decreased protein export from nucleus during glucose deprivation" EXACT [PomBase:mah] synonym: "decreased protein export from nucleus during glucose limitation" RELATED [PomBase:mah] synonym: "reduced protein export from nucleus during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0005745 ! abnormal protein export from nucleus created_by: midori creation_date: 2016-11-02T15:22:57Z [Term] id: FYPO:0005747 name: normal protein transport def: "A cellular process phenotype in which protein transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0000149 ! transport phenotype is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2016-11-02T15:26:30Z [Term] id: FYPO:0005748 name: normal protein export from nucleus during glucose starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein export from nucleus is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal protein export from nucleus during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "normal protein export from nucleus during glucose depletion" EXACT [PomBase:mah] synonym: "normal protein export from nucleus during glucose deprivation" EXACT [PomBase:mah] synonym: "normal protein export from nucleus during glucose limitation" RELATED [PomBase:mah] is_a: FYPO:0005747 ! normal protein transport created_by: midori creation_date: 2016-11-02T15:27:50Z [Term] id: FYPO:0005749 name: decreased protein phosphorylation during glucose starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during glucose depletion" EXACT [PomBase:vw] synonym: "decreased protein phosphorylation during glucose deprivation" EXACT [PomBase:vw] synonym: "decreased protein phosphorylation during glucose limitation" RELATED [PomBase:mah] synonym: "reduced protein phosphorylation during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0002679 ! decreased protein phosphorylation created_by: midori creation_date: 2016-11-02T15:35:40Z [Term] id: FYPO:0005750 name: sensitive to Zeocin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Zeocin (phleomycin D1). Cells stop growing (and may die) at a concentration of Zeocin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Zeocin" EXACT [PomBase:mah] synonym: "sensitive to phleomycin D1" EXACT [CHEBI:75046] synonym: "sensitive to Zeocin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to Zeocin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-11-02T15:44:22Z [Term] id: FYPO:0005751 name: normal growth on Zeocin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Zeocin (phleomycin D1)." [PomBase:mah] synonym: "normal cell population growth in presence of Zeocin" EXACT [PomBase:mah] synonym: "normal cell population growth on phleomycin D1" EXACT [CHEBI:75046] synonym: "normal cell population growth on Zeocin" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on Zeocin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2016-11-02T15:46:15Z [Term] id: FYPO:0005752 name: increased cellular dNTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dNTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular dNTP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased dNTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-11-02T15:48:18Z [Term] id: FYPO:0005753 name: normal cellular dNTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular dNTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular dNTP level during vegetative growth" EXACT [PomBase:mah] synonym: "normal dNTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2016-11-02T15:51:41Z [Term] id: FYPO:0005754 name: increased (1->3)-alpha-D-glucan level in periplasmic space def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-alpha-D-glucan measured in the periplasmic space is greater than normal." [PMID:11514435, PomBase:mah] comment: This term can be used when increased Calcofluor White staining is observed at the cell tip, as Calcofluor White binds specifically to linear (1->3)-beta-D-glucans in fission yeast. synonym: "increased (1,3)alpha-D-glucan level in periplasmic space" EXACT [PomBase:mah] synonym: "increased (1->3)-alpha-D-glucan accumulation in periplasmic space" RELATED [PomBase:mah] synonym: "increased (1->3)-alpha-D-glucan level in periplasmic space during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased (1->3)-alpha-D-glucan level in periplasmic space during vegetative growth" EXACT [PomBase:mah] synonym: "increased 1,3-alpha-D-glucan level in periplasmic space" EXACT [CHEBI:28100] synonym: "increased level of (1->3)-alpha-D-glucan in periplasmic space" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2016-11-02T16:04:39Z [Term] id: FYPO:0005755 name: increased (1->3)-beta-D-glucan level in periplasmic space def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-beta-D-glucan measured in the periplasmic space is greater than normal." [PMID:11514435, PomBase:mah] comment: This term can be used when increased Calcofluor White staining is observed at the cell tip, as Calcofluor White binds specifically to linear (1->3)-beta-D-glucans in fission yeast. synonym: "increased (1,3)beta-D-glucan level in periplasmic space" EXACT [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan accumulation in periplasmic space" RELATED [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan level in periplasmic space during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased (1->3)-beta-D-glucan level in periplasmic space during vegetative growth" EXACT [PomBase:mah] synonym: "increased 1,3-beta-D-glucan level in periplasmic space" EXACT [CHEBI:37671] synonym: "increased level of (1->3)-beta-D-glucan in periplasmic space" EXACT [PomBase:mah] is_a: FYPO:0007949 ! increased (1->3)-beta-D-glucan level created_by: midori creation_date: 2016-11-02T16:09:12Z [Term] id: FYPO:0005756 name: normal cellular mannosylinositol phosphorylceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mannosylinositol phosphorylceramide (MIPC) measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular mannose-inositol-phosphoceramide level" EXACT [PMID:11514435] synonym: "normal cellular mannosylinositol phosphorylceramide accumulation" RELATED [PomBase:mah] synonym: "normal cellular mannosylinositol phosphorylceramide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular mannosylinositol phosphorylceramide level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular MIPC level" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2016-11-02T16:15:36Z [Term] id: FYPO:0005757 name: abolished protein localization to membrane during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more membranes does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to membrane during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from membrane during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to membrane abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2016-11-02T16:19:12Z [Term] id: FYPO:0005758 name: abnormal regulation of mitotic DNA replication initiation from late origin def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of mitotic DNA replication from late-firing origins is abnormal." [GO:0101017, PMID:22987637, PomBase:mah] synonym: "abnormal regulation of DNA replication initiation from late origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of late origin firing timing" RELATED [PMID:22987637] synonym: "abnormal regulation of mitotic DNA replication initiation at late origin" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic DNA replication initiation from late origin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic DNA replication initiation from late replication origin" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0004756 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2016-11-04T11:31:37Z [Term] id: FYPO:0005759 name: increased protein localization to chromatin at late replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at late-firing replication origins is increased." [PMID:22987637, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at late replication origin" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at late origin" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at late replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at late replication origins during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004961 ! increased protein localization to chromatin at replication origin created_by: midori creation_date: 2016-11-04T11:34:57Z [Term] id: FYPO:0005760 name: increased cell-cell adhesion def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells adhere to each other more strongly or to a greater extent than normal." [GO:0098610, PomBase:mah] synonym: "increased adhesion between unicellular organisms" EXACT [GO:0098610] synonym: "increased cell-cell adhesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cell-cell adhesion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth created_by: midori creation_date: 2016-11-04T11:48:00Z [Term] id: FYPO:0005761 name: normal protein O-linked glycosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein glycosylation is normal (i.e. indistinguishable from wild type). Protein O-linked glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid via a hydroxyl or phenol group, forming an O-glycan." [GO:0006493, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein amino acid O-linked glycosylation during vegetative growth" EXACT [GO:0006493] synonym: "normal protein O-linked glycosylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein/peptide O-linked glycosylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2016-11-04T11:58:31Z [Term] id: FYPO:0005762 name: abolished homocitrate synthase activity def: "A molecular function phenotype in which homocitrate synthase activity is absent." [PomBase:mah] synonym: "homocitrate synthase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001750 ! abnormal homocitrate synthase activity created_by: midori creation_date: 2016-11-04T12:03:40Z [Term] id: FYPO:0005763 name: increased replication fork pausing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal, including at sites where forks do not normally pause." [PMID:25471935, PMID:27611590, PomBase:mah] synonym: "increased replication fork pausing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork pausing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003923 ! decreased rate of mitotic DNA replication elongation created_by: midori creation_date: 2016-11-04T13:24:43Z [Term] id: FYPO:0005764 name: increased replication fork pausing at G4 motif def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal in regions containing G-quartet (G4) motifs." [PMID:25471935, PMID:27611590, PomBase:mah] synonym: "increased replication fork pausing at G-quadruplex" EXACT [SO:0000003] synonym: "increased replication fork pausing at G-quartet" EXACT [SO:0000003] synonym: "increased replication fork pausing at G4 motif during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork pausing at G4 motif during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005763 ! increased replication fork pausing created_by: midori creation_date: 2016-11-04T13:51:55Z [Term] id: FYPO:0005765 name: increased replication fork pausing at highly transcribed RNA polymerase II genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal in regions where RNA polymerase II actively transcribes genes." [PMID:27611590, PomBase:mah] synonym: "increased replication fork pausing at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork pausing at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003925 ! decreased rate of mitotic DNA replication elongation at highly transcribed RNA polymerase II genes is_a: FYPO:0005763 ! increased replication fork pausing created_by: midori creation_date: 2016-11-04T14:01:51Z [Term] id: FYPO:0005766 name: increased replication fork pausing at nucleosome-depleted regions def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal in regions where nucleosomes are depleted." [PMID:27611590, PomBase:mah] synonym: "increased replication fork pausing at nucleosome-depleted regions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork pausing at nucleosome-depleted regions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005763 ! increased replication fork pausing created_by: midori creation_date: 2016-11-04T14:04:27Z [Term] id: FYPO:0005767 name: increased replication fork pausing at tRNA genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal at tRNA genes." [PMID:27611590, PomBase:mah] synonym: "increased replication fork pausing at transfer RNA genes" EXACT [PomBase:mah] synonym: "increased replication fork pausing at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork pausing at tRNA genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005763 ! increased replication fork pausing created_by: midori creation_date: 2016-11-04T14:05:41Z [Term] id: FYPO:0005768 name: increased replication fork pausing at rDNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal at ribosomal DNA." [PMID:27611590, PomBase:mah] synonym: "increased replication fork pausing at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication fork pausing at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased replication fork pausing at ribosomal DNA" EXACT [PomBase:mah] synonym: "increased replication fork pausing at ribosomal RNA genes" EXACT [PomBase:mah] synonym: "increased replication fork pausing at rRNA genes" EXACT [SO:0001637] is_a: FYPO:0005763 ! increased replication fork pausing created_by: midori creation_date: 2016-11-04T14:06:45Z [Term] id: FYPO:0005769 name: increased histone H2A phosphorylation at G4 motif during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal in regions containing G-quartet (G4) motifs. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:25471935, PMID:27611590, PomBase:mah] synonym: "increased histone H2A phosphorylation at G-quadruplex during vegetative growth" EXACT [GO:0000003] synonym: "increased histone H2A phosphorylation at G-quartet during vegetative growth" EXACT [SO:0000003] synonym: "increased histone H2A phosphorylation at G4 motif during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2016-11-04T14:27:48Z [Term] id: FYPO:0005770 name: increased histone H2A phosphorylation at highly transcribed RNA polymerase II genes during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal in regions where RNA polymerase II actively transcribes genes. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:27611590, PomBase:mah] synonym: "increased histone H2A phosphorylation at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2016-11-04T14:38:13Z [Term] id: FYPO:0005771 name: increased histone H2A phosphorylation at nucleosome-depleted regions during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal in regions where nucleosomes are depleted. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:27611590, PomBase:mah] synonym: "increased histone H2A phosphorylation at nucleosome-depleted regions during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2016-11-04T14:39:53Z [Term] id: FYPO:0005772 name: increased histone H2A phosphorylation at tRNA genes during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at tRNA genes. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:27611590, PomBase:mah] synonym: "increased histone H2A phosphorylation at transfer RNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2016-11-04T14:41:29Z [Term] id: FYPO:0005773 name: elongated mononucleate aseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is elongated, has no septum, and contains one nucleus." [PomBase:mah] synonym: "elongated aseptate mononucleate vegetative cell" EXACT [PomBase:mah] synonym: "elongated mononucleate aseptate cells during vegetative growth" EXACT [PomBase:mah] synonym: "elongated mononucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000950 ! elongated aseptate vegetative cell is_a: FYPO:0001916 ! elongated mononucleate vegetative cell is_a: FYPO:0003785 ! aseptate mononucleate vegetative cell created_by: midori creation_date: 2016-11-04T14:59:42Z [Term] id: FYPO:0005774 name: decreased cellular magnesium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of magnesium ions measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular magnesium ion level" EXACT [PomBase:mah] synonym: "decreased cellular magnesium level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular magnesium level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased magnesium accumulation" RELATED [PomBase:al] synonym: "reduced cellular magnesium level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2016-11-04T15:01:22Z [Term] id: FYPO:0005775 name: sensitive to acetaldehyde def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acetaldehyde. Cells stop growing (and may die) at a concentration of acetaldehyde that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to acetaldehyde" EXACT [PomBase:mah] synonym: "sensitive to acetaldehyde during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to acetaldehyde during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000266 ! sensitive to DNA damaging agents created_by: midori creation_date: 2016-11-04T15:04:47Z [Term] id: FYPO:0005776 name: normal growth on acetaldehyde def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing v." [PomBase:mah] synonym: "normal cell population growth in presence of acetaldehyde" EXACT [PomBase:mah] synonym: "normal cell population growth on acetaldehyde" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on acetaldehyde" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2016-11-04T15:05:40Z [Term] id: FYPO:0005777 name: increased number of Rad52 foci during cellular response to acetaldehyde def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to acetaldehyde." [PMID:27687866, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during cellular response to acetaldehyde" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to acetaldehyde during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to acetaldehyde during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2016-11-04T15:09:40Z [Term] id: FYPO:0005778 name: abnormal chromosome morphology during cellular response to acetaldehyde def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of one or more chromosomes is abnormal during a cellular response to acetaldehyde." [PomBase:mah] comment: Note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. synonym: "abnormal chromosome morphology during cellular response to acetaldehyde during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromosome morphology during cellular response to acetaldehyde during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth created_by: midori creation_date: 2016-11-04T15:11:12Z [Term] id: FYPO:0005779 name: normal protein localization to kinetochore during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein localization to kinetochore during mitotic nuclear division" RELATED [GO:0140014] is_a: FYPO:0002901 ! normal protein localization to kinetochore during vegetative growth created_by: midori creation_date: 2016-11-09T13:35:38Z [Term] id: FYPO:0005780 name: decreased response to mitotic spindle assembly checkpoint signaling def: "A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the mitotic spindle assembly checkpoint is decreased. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions." [GO:0072479, PomBase:mah] synonym: "decreased mitotic spindle assembly checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "decreased response to mitotic cell cycle spindle assembly checkpoint signaling" EXACT [GO:0072479] synonym: "decreased spindle assembly checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced response to mitotic spindle assembly checkpoint signaling" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint created_by: midori creation_date: 2016-11-09T13:49:57Z [Term] id: FYPO:0005781 name: decreased duration of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic spindle assembly checkpoint is lower than in wild type." [PomBase:mah] synonym: "decreased duration of mitotic cell cycle spindle assembly checkpoint" EXACT [GO:0007094] synonym: "decreased duration of mitotic spindle assembly checkpoint activation" EXACT [PomBase:mah] synonym: "decreased duration of mitotic spindle assembly checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of spindle assembly checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic spindle assembly checkpoint deactivation" RELATED [PomBase:mah] synonym: "reduced duration of mitotic spindle assembly checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint created_by: midori creation_date: 2016-11-09T13:50:11Z [Term] id: FYPO:0005782 name: decreased mitotic checkpoint complex level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer mitotic checkpoint complexes than normal." [GO:0033597, PMID:26882497, PomBase:mah] synonym: "decreased MCC level" RELATED [GO:0033597] synonym: "decreased mitotic checkpoint complex level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic checkpoint complex level during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic checkpoint complexes present at decreased level" EXACT [PomBase:mah] synonym: "reduced mitotic checkpoint complex level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2016-11-09T14:18:35Z [Term] id: FYPO:0005783 name: normal mitotic checkpoint complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic checkpoint complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal MCC assembly" EXACT [GO:1905660] synonym: "normal mitotic checkpoint complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic checkpoint complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2016-11-09T14:24:42Z [Term] id: FYPO:0005784 name: decreased extent and duration of protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent, and for a shorter time, than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PMID:26882497, PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased extent and duration of protein binding" EXACT [PomBase:mah] synonym: "decreased level and duration of protein-protein interaction" EXACT [PomBase:mah] synonym: "reduced extent and duration of protein-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0005785 ! decreased duration of protein-protein interaction created_by: midori creation_date: 2016-11-09T14:26:18Z [Term] id: FYPO:0005785 name: decreased duration of protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another occurs for a shorter time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PMID:26882497, PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased duration of protein binding" EXACT [PomBase:mah] synonym: "reduced duration of protein-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2016-11-09T14:27:22Z [Term] id: FYPO:0005786 name: decreased spatial extent of double-strand break processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a shorter distance from the breaks site than normal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang." [GO:0000729, PMID:27729451, PomBase:mah] synonym: "decreased spatial extent of double-strand break processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spatial extent of double-strand break processing during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spatial extent of double-strand break resection" EXACT [PomBase:mah] synonym: "decreased spatial extent of DSB processing" EXACT [PomBase:mah] synonym: "reduced spatial extent of double-strand break processing" EXACT [PomBase:mah] is_a: FYPO:0002553 ! abnormal double-strand break processing created_by: midori creation_date: 2016-11-09T14:36:22Z [Term] id: FYPO:0005787 name: normal spatial extent of double-strand break processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a normal (i.e. indistinguishable from wild type) distance from the break site. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang." [GO:0000729, PMID:27729451, PomBase:mah] synonym: "normal spatial extent of double-strand break processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spatial extent of double-strand break processing during vegetative growth" EXACT [PomBase:mah] synonym: "normal spatial extent of double-strand break resection" EXACT [PomBase:mah] synonym: "normal spatial extent of DSB processing" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-11-09T14:40:38Z [Term] id: FYPO:0005788 name: increased gene conversion during vegetative growth def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion occurs to a greater extent than normal." [PomBase:mah] synonym: "increased gene conversion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2016-11-11T11:28:28Z [Term] id: FYPO:0005789 name: C-shaped vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis to form a \"C\" shape. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a C-shaped cell, the curve is centered at the midpoint of the long axis of the cell." [PomBase:mah] synonym: "C-shaped cell" EXACT [PomBase:mah] synonym: "C-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "C-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell morphology, C-shaped" EXACT [PomBase:mah] is_a: FYPO:0000016 ! curved vegetative cell created_by: midori creation_date: 2016-11-11T11:39:05Z [Term] id: FYPO:0005790 name: J-shaped vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis to form a \"J\" shape. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a J-shaped cell, the curve is centered away from the midpoint of the long axis of the cell." [PomBase:mah] synonym: "cell morphology, J-shaped" EXACT [PomBase:mah] synonym: "J-shaped cell" EXACT [PomBase:mah] synonym: "J-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "J-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000016 ! curved vegetative cell created_by: midori creation_date: 2016-11-11T11:41:29Z [Term] id: FYPO:0005791 name: abnormal shmoo directionality def: "A cellular process phenotype in which a shmoo forms with normal morphology, but in an abnormal location." [GO:0000753, PMID:23200991, PomBase:mah] synonym: "abnormal cell morphogenesis involved in conjugation with cellular fusion" EXACT [GO:0000753] synonym: "abnormal shmoo orientation" NARROW [GO:0000753] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2016-11-23T12:50:31Z [Term] id: FYPO:0005792 name: T-shaped cell during G0 to G2 transition def: "A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell undergoes transition from G0 phase to G2. Cell length is normal." [PomBase:mah, PomBase:vw] comment: Cells enter quiescence (G0) from G2 when starved for glucose, and can re-enter the cell cycle at G2 when glucose again becomes available. A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell morphology, T shaped during G0 to G2 transition" EXACT [PomBase:mah] synonym: "T-shaped cell during cell cycle re-entry at G2" EXACT [PomBase:mah] synonym: "T-shaped cell during cell quiescence to G2 transition" EXACT [PomBase:mah] synonym: "T-shaped cell during exit from cell quiescence into G2" EXACT [PomBase:mah] synonym: "T-shaped cell during quiescence to G2 transition" EXACT [PomBase:mah] synonym: "T-shaped cell during recovery from quiescence following G2 arrest" EXACT [PomBase:mah] synonym: "T-shaped cell during recovery from quiescence into G2" EXACT [PomBase:vw] is_a: FYPO:0005810 ! T-shaped cell during recovery from quiescence created_by: midori creation_date: 2016-11-23T13:01:05Z [Term] id: FYPO:0005793 name: bent cell def: "A cell morphology phenotype in which a cell is bent along the long axis. In a bent cell, the long axis has one or more angles, rather than following a straight line." [PomBase:mah] synonym: "cell morphology, bent" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2016-11-23T13:06:05Z [Term] id: FYPO:0005794 name: bent cell during G0 to G1 transition def: "A cell morphology phenotype in which a cell is bent along the long axis when the cell undergoes transition from G0 phase to G1. In a bent cell, the long axis has one or more angles, rather than following a straight line." [PomBase:mah] comment: A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "bent cell during cell cycle re-entry at G1" EXACT [PomBase:mah] synonym: "bent cell during cell quiescence to G1 transition" EXACT [PomBase:mah] synonym: "bent cell during exit from cell quiescence into G1" EXACT [PomBase:mah] synonym: "bent cell during quiescence to G1 transition" EXACT [PomBase:mah] synonym: "bent cell during recovery from quiescence following G1 arrest" EXACT [PomBase:mah] synonym: "bent cell during recovery from quiescence into G1" EXACT [PomBase:vw] is_a: FYPO:0005793 ! bent cell created_by: midori creation_date: 2016-11-23T13:07:10Z [Term] id: FYPO:0005796 name: short disorganized microtubule bundle def: "A physical cellular phenotype in which microtubule bundles are shorter than normal and have an abnormal structure. Typically, microtubule bundles do not reach the cell tips and are not aligned parallel to the long axis of the cell." [PMID:11007487, PomBase:mah] synonym: "short disorganised microtubule bundle" EXACT [PomBase:mah] synonym: "short disorganized microtubule array" RELATED [PomBase:vw] synonym: "short microtubule bundle with abnormal structure" EXACT [PomBase:mah] is_a: FYPO:0005797 ! short microtubule bundle created_by: midori creation_date: 2016-11-23T13:21:21Z [Term] id: FYPO:0005797 name: short microtubule bundle def: "A physical cellular phenotype in which microtubule bundles are shorter than normal." [PomBase:mah] synonym: "decreased microtubule bundle length" EXACT [PomBase:mah] synonym: "short microtubule array" RELATED [PomBase:vw] synonym: "short MT bundles" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0005558 ! abnormal microtubule bundle created_by: midori creation_date: 2016-11-23T13:24:48Z [Term] id: FYPO:0005798 name: decreased protein localization to cell cortex of cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex of cell end during vegetative growth" RELATED [PomBase:mah] synonym: "decreased protein localization to cell cortex of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell tip cortex during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006875 ! abnormal protein localization to cell cortex of cell tip during vegetative growth created_by: midori creation_date: 2016-11-23T13:27:03Z [Term] id: FYPO:0005799 name: decreased microtubule dwell time at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule plus ends remain in contact with the cell cortex at cell tips for a shorter time than normal." [PMID:11007487, PomBase:mah] synonym: "decreased microtubule dwell time at cell end" EXACT [PomBase:mah] synonym: "decreased microtubule dwell time at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased microtubule dwell time at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule plus end dwell time at cell tip" EXACT [PMID:24530531] synonym: "reduced microtubule dwell time at cell tip" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2016-11-23T13:29:13Z [Term] id: FYPO:0005800 name: abnormal protein movement within plasma membrane during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane is abnormal." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein movement within plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2016-11-23T13:44:06Z [Term] id: FYPO:0005801 name: decreased rate of protein movement within plasma membrane at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the cell tip occurs more slowly than normal." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased rate of protein movement within plasma membrane at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of protein movement within plasma membrane at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of protein movement within plasma membrane at cell tip" EXACT [PomBase:mah] synonym: "slow protein movement within plasma membrane at cell tip" EXACT [PomBase:mah] is_a: FYPO:0005800 ! abnormal protein movement within plasma membrane during vegetative growth created_by: midori creation_date: 2016-11-23T13:45:53Z [Term] id: FYPO:0005802 name: increased rate of protein movement within plasma membrane at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the cell tip occurs more quickly than normal." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "fast protein movement within plasma membrane at cell tip" EXACT [PomBase:mah] synonym: "increased rate of protein movement within plasma membrane at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of protein movement within plasma membrane at cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005800 ! abnormal protein movement within plasma membrane during vegetative growth created_by: midori creation_date: 2016-11-23T13:48:01Z [Term] id: FYPO:0005803 name: decreased rate of protein movement within plasma membrane at cell side def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the lateral part of the cell occurs more slowly than normal." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased rate of protein movement within plasma membrane at cell side during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of protein movement within plasma membrane at cell side during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of protein movement within plasma membrane at lateral part of cell" EXACT [GO:0097574] synonym: "reduced rate of protein movement within plasma membrane at cell side" EXACT [PomBase:mah] synonym: "slow protein movement within plasma membrane at cell side" EXACT [PomBase:mah] is_a: FYPO:0005800 ! abnormal protein movement within plasma membrane during vegetative growth created_by: midori creation_date: 2016-11-23T13:48:58Z [Term] id: FYPO:0005804 name: normal protein movement within plasma membrane during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane is normal (i.e. indistinguishable from wild type)." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein movement within plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0005807 ! normal protein movement within plasma membrane created_by: midori creation_date: 2016-11-23T13:55:36Z [Term] id: FYPO:0005805 name: normal rate of protein movement within plasma membrane at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of movement of one or more proteins within the plasma membrane of the cell tip is normal (i.e. indistinguishable from wild type)." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal rate of protein movement within plasma membrane at cell end" EXACT [PomBase:mah] synonym: "normal rate of protein movement within plasma membrane at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of protein movement within plasma membrane at cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005804 ! normal protein movement within plasma membrane during vegetative growth created_by: midori creation_date: 2016-11-23T14:10:06Z [Term] id: FYPO:0005806 name: normal rate of protein movement within plasma membrane at cell side def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of movement of one or more proteins within the plasma membrane of the lateral part of the cell is normal (i.e. indistinguishable from wild type)." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal rate of protein movement within plasma membrane at cell side during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of protein movement within plasma membrane at cell side during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of protein movement within plasma membrane at lateral part of cell" EXACT [GO:0097574] is_a: FYPO:0005804 ! normal protein movement within plasma membrane during vegetative growth created_by: midori creation_date: 2016-11-23T14:11:26Z [Term] id: FYPO:0005807 name: normal protein movement within plasma membrane def: "A cellular process phenotype in which the movement of one or more proteins within the plasma membrane is normal (i.e. indistinguishable from wild type)." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2016-11-25T13:54:41Z [Term] id: FYPO:0005808 name: normal rate of protein movement within spore plasma membrane def: "A cellular process phenotype in which the rate, or speed, of movement of one or more proteins within the plasma membrane of a spore is normal (i.e. indistinguishable from wild type)." [PMID:25837586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0005807 ! normal protein movement within plasma membrane created_by: midori creation_date: 2016-11-25T13:57:04Z [Term] id: FYPO:0005809 name: short astral microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form astral microtubules that are shorter than normal." [PomBase:mah] synonym: "short astral microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short astral microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "short cytoplasmic astral microtubules" EXACT [PomBase:vw] is_a: FYPO:0002760 ! short cytoplasmic microtubules created_by: midori creation_date: 2016-11-25T14:08:36Z [Term] id: FYPO:0005810 name: T-shaped cell during recovery from quiescence def: "A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell undergoes transition from G0 phase, re-entering the cell cycle phase from which it entered G0 (G1 or G2). Cell length is normal." [PomBase:mah, PomBase:vw] comment: A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell morphology, T shaped during recovery from quiescence" EXACT [PomBase:mah] synonym: "T-shaped cell during cell cycle re-entry" EXACT [PomBase:mah] synonym: "T-shaped cell during exit from cell quiescence" EXACT [PomBase:mah] synonym: "T-shaped cell during recovery from stationary phase" RELATED [PomBase:jh, PomBase:vw] synonym: "T-shaped cell during transition from cell quiescence" EXACT [PomBase:mah] is_a: FYPO:0005566 ! T-shaped cell created_by: midori creation_date: 2016-11-25T14:22:18Z [Term] id: FYPO:0005811 name: abnormal nuclear membrane biogenesis involved in mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the biogenesis of nuclear membrane that normally forms part of mitosis is abnormal." [PMID:26869222, PomBase:mah] synonym: "abnormal membrane addition to the nuclear membrane during division" EXACT [PomBase:vw] synonym: "abnormal nuclear membrane biogenesis involved in mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nuclear membrane biogenesis involved in mitotic nuclear division" EXACT [GO:0101026] synonym: "abnormal nuclear membrane biogenesis involved nuclear division during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2016-11-25T14:50:59Z [Term] id: FYPO:0005813 name: normal protein localization to microtubule end during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or both ends of a microtubule is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to microtubule end during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to microtubule end during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to microtubule end during interphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0005397 ! normal intracellular protein transport during vegetative growth created_by: midori creation_date: 2016-11-28T15:00:40Z [Term] id: FYPO:0005814 name: abolished protein localization to microtubule plus-end def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends of microtubules does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule plus-end" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule plus end" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule plus-end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to microtubule plus-end during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to microtubule plus-end abolished" EXACT [PomBase:mah] is_a: FYPO:0000934 ! abolished protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2016-11-28T15:13:26Z [Term] id: FYPO:0005815 name: abnormal protein localization to perinuclear region of cytoplasm during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the perinuclear region of the cytoplasm is abnormal during mitotic nuclear division." [GO:1905719, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to perinuclear region of cytoplasm during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal protein localization to perinuclear region of cytoplasm during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to perinuclear region of cytoplasm during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein localisation to nuclear region during mitotic interphase" RELATED [PomBase:vw] synonym: "protein localization to nuclear region during mitotic interphase" RELATED [PomBase:vw] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2016-11-28T15:27:23Z [Term] id: FYPO:0005816 name: normal microtubule-based movement def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule-based movement is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal microtubule-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal microtubule-based movement during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2016-11-28T15:39:21Z [Term] id: FYPO:0005817 name: abolished protein localization to microtubule plus-end during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or both ends end of a microtubule does not occur during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule plus-end during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule plus end during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule plus-end during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule plus-end during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein localization to microtubule plus-end abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0005441 ! abolished protein localization to microtubule during mitotic interphase is_a: FYPO:0005814 ! abolished protein localization to microtubule plus-end created_by: midori creation_date: 2016-11-30T13:57:03Z [Term] id: FYPO:0005818 name: normal protein neddylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the neddylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein neddylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein neddylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein/peptide neddylation" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2016-11-30T14:17:47Z [Term] id: FYPO:0005819 name: abnormal protein neddylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the neddylation of one or more specific proteins, or of specific protein sites, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein neddylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2016-11-30T14:19:12Z [Term] id: FYPO:0005820 name: increased protein neddylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of neddylation of one or more specific proteins, or of specific protein sites, is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein neddylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005819 ! abnormal protein neddylation during vegetative growth created_by: midori creation_date: 2016-11-30T14:19:19Z [Term] id: FYPO:0005821 name: abnormal NEDD8-specific protease activity def: "A molecular function phenotype in which the observed rate of NEDD8-specific protease activity (deneddylase activity) is abnormal." [PomBase:mah] comment: Secreted invertase activity is usually measured. synonym: "abnormal deneddylase activity" EXACT [GO:0019784] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-11-30T14:21:44Z [Term] id: FYPO:0005822 name: decreased NEDD8-specific protease activity def: "A molecular function phenotype in which the observed rate of NEDD8-specific protease activity (deneddylase activity) is decreased under conditions of glucose starvation." [PomBase:mah] synonym: "decreased deneddylase activity" EXACT [GO:0019784] synonym: "reduced NEDD8-specific protease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005821 ! abnormal NEDD8-specific protease activity created_by: midori creation_date: 2016-11-30T14:21:50Z [Term] id: FYPO:0005823 name: increased phosphatidylserine externalization def: "A cell phenotype in which the amount of phosphatidylserine measured in the outer leaflet of the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle. Normally, phosphatidylserine is restricted to the inner leaflet of the plasma membrane." [PMID:20192774, PMID:27886462, PomBase:mah] comment: The appearance of phosphatidylserine on the external side of the plasma membrane is a marker for apoptosis. synonym: "increased phosphatidylserine externalisation" EXACT [PomBase:mah] synonym: "increased phosphatidylserine externalization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phosphatidylserine externalization during vegetative growth" EXACT [PomBase:mah] synonym: "increased phosphatidylserine level in external side of cell membrane during vegetative growth" EXACT [GO:0005886] synonym: "increased phosphatidylserine level in outer leaflet of plasma membrane" EXACT [GO:0009897] synonym: "increased PS externalization" EXACT [PomBase:mah] is_a: FYPO:0001505 ! increased cellular phosphatidylserine level created_by: midori creation_date: 2016-12-05T15:02:42Z [Term] id: FYPO:0005824 name: increased plasma membrane permeability def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the permeability of the plasma membrane to one or more substances is greater than normal." [PMID:27886462, PomBase:mah] comment: Note that an abnormal plasma membrane organization process may, but does not necessarily, result in abnormal plasma membrane morphology. synonym: "increased plasma membrane permeability during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased plasma membrane permeability during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000364 ! abnormal plasma membrane morphology during vegetative growth created_by: midori creation_date: 2016-12-05T15:08:33Z [Term] id: FYPO:0005825 name: sensitive to iron def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to iron ions. Cells stop growing (and may die) at a concentration of iron ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to iron" EXACT [PomBase:mah] synonym: "sensitive to iron during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to iron during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to iron ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2016-12-05T15:53:22Z [Term] id: FYPO:0005826 name: decreased level of generation of precursor metabolites and energy gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more generation of precursor metabolites and energy RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Generation of precursor metabolites and energy RNAs are transcribed from genes whose products are involved in the formation of precursor metabolites and the liberation of energy from these substances." [GO:0006091, PMID:25102102, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased generation of precursor metabolites and energy RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of generation of precursor metabolites and energy gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of generation of precursor metabolites and energy RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of generation of precursor metabolites and energy transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "reduced level of generation of precursor metabolites and energy gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2016-12-05T15:54:46Z [Term] id: FYPO:0005827 name: normal protein transport along microtubule during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein movement along microtubule during vegetative growth" EXACT [PomBase:vw] synonym: "normal protein transport along microtubule during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005397 ! normal intracellular protein transport during vegetative growth is_a: FYPO:0005816 ! normal microtubule-based movement created_by: midori creation_date: 2016-12-06T11:36:52Z [Term] id: FYPO:0005828 name: normal protein transport along microtubule to cell tip during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein movement along microtubule to cell tip during vegetative growth" EXACT [PomBase:vw] synonym: "normal protein transport along microtubule to cell tip during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005827 ! normal protein transport along microtubule during vegetative growth created_by: midori creation_date: 2016-12-06T11:39:20Z [Term] id: FYPO:0005830 name: abnormal protein transport along microtubule during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules is abnormal. Transport of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein movement along microtubule during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal protein transport along microtubule during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport during vegetative growth created_by: midori creation_date: 2016-12-06T12:03:55Z [Term] id: FYPO:0005831 name: abnormal protein transport along microtubule to cell tip during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip is abnormal. Transport of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein movement along microtubule to cell tip during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal protein transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005830 ! abnormal protein transport along microtubule during vegetative growth created_by: midori creation_date: 2016-12-06T12:04:42Z [Term] id: FYPO:0005832 name: abnormal protein transport along microtubule to cell tip cortex during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cortex of the cell tip is abnormal. Transport of all proteins or a specific protein may be affected." [GO:0099110, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein movement along microtubule to cell tip cortex during vegetative growth" EXACT [PomBase:vw] synonym: "abnormal protein transport along microtubule to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein transport along microtubule to cell tip cortex during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005830 ! abnormal protein transport along microtubule during vegetative growth created_by: midori creation_date: 2016-12-06T12:04:50Z [Term] id: FYPO:0005833 name: decreased protein transport along microtubule to cell tip during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip is decreased. Transport of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein movement along microtubule to cell tip during vegetative growth" EXACT [PomBase:vw] synonym: "decreased protein transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein transport along microtubule to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005831 ! abnormal protein transport along microtubule to cell tip during vegetative growth created_by: midori creation_date: 2016-12-06T12:09:45Z [Term] id: FYPO:0005834 name: decreased protein transport along microtubule to cell tip cortex during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached, is decreased. Transport of all proteins or a specific protein may be affected." [GO:0099110, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein movement along microtubule to cell tip cortex during vegetative growth" EXACT [PomBase:vw] synonym: "decreased protein transport along microtubule to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein transport along microtubule to cell tip cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein transport along microtubule to cell tip cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005494 ! decreased protein transport along microtubule during vegetative growth is_a: FYPO:0005832 ! abnormal protein transport along microtubule to cell tip cortex during vegetative growth is_a: FYPO:0005833 ! decreased protein transport along microtubule to cell tip during vegetative growth created_by: midori creation_date: 2016-12-06T12:10:02Z [Term] id: FYPO:0005835 name: abolished protein transport along microtubule during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins along microtubules does not occur. Transport of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay. synonym: "abolished protein movement along microtubule during vegetative growth" EXACT [PomBase:vw] synonym: "abolished protein transport along microtubule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein transport along microtubule abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005830 ! abnormal protein transport along microtubule during vegetative growth created_by: midori creation_date: 2016-12-06T12:15:12Z [Term] id: FYPO:0005836 name: abolished protein transport along microtubule to cell tip during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip does not occur. Transport of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein movement along microtubule to cell tip during vegetative growth" EXACT [PomBase:vw] synonym: "abolished protein transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein transport along microtubule to cell tip abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005831 ! abnormal protein transport along microtubule to cell tip during vegetative growth created_by: midori creation_date: 2016-12-06T12:16:24Z [Term] id: FYPO:0005837 name: abolished protein transport along microtubule to cell tip cortex during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cortex of the cell tip does not occur. Transport of all proteins or a specific protein may be affected." [GO:0099110, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein movement along microtubule to cell tip cortex during vegetative growth" EXACT [PomBase:vw] synonym: "abolished protein transport along microtubule to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein transport along microtubule to cell tip cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein transport along microtubule to cell tip cortex abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005832 ! abnormal protein transport along microtubule to cell tip cortex during vegetative growth is_a: FYPO:0005836 ! abolished protein transport along microtubule to cell tip during vegetative growth created_by: midori creation_date: 2016-12-06T12:16:30Z [Term] id: FYPO:0005838 name: symmetric mitochondrial aggregation def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal with a cluster distal to each side of the nucleus." [PomBase:mah] synonym: "bipolar intracellular mitochondrion distribution" RELATED [PomBase:mah] synonym: "bipolar intracellular mitochondrion localisation" RELATED [PomBase:mah] synonym: "bipolar intracellular mitochondrion localization" RELATED [PomBase:mah] synonym: "bipolar mitochondrial aggregation" RELATED [PomBase:mah] synonym: "bipolar mitochondrion distribution" RELATED [PomBase:mah] synonym: "symmetric mitochondrial aggregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "symmetric mitochondrial aggregation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000895 ! mitochondrial aggregation created_by: midori creation_date: 2016-12-09T14:54:04Z [Term] id: FYPO:0005839 name: increased rate of medial membrane band assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of medial membrane band assembly is increased. Medial membrane band assembly is the assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring." [GO:0032130, PomBase:mah] synonym: "increased rate of medial membrane band assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of medial membrane band assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of medial membrane band formation" EXACT [GO:0032130, PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2016-12-12T14:47:11Z [Term] id: FYPO:0005840 name: incomplete, asymmetric septum def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that does not have uniform thickness and does not extend over the entire cell division site." [PMID:26877082, PomBase:mah] synonym: "discontinuous, asymmetric secondary septum" EXACT [PMID:25473118] synonym: "incomplete, asymmetric secondary cell septum" EXACT [PomBase:mah] synonym: "incomplete, asymmetric secondary cell septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "incomplete, asymmetric secondary cell septum during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete, asymmetric secondary septum" EXACT [PomBase:mah] is_a: FYPO:0005870 ! incomplete septum created_by: midori creation_date: 2016-12-12T15:12:35Z [Term] id: FYPO:0005841 name: normal protein transport along microtubule to cell tip cortex during vegetative growth alt_id: FYPO:0005829 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cortex of the cell tip is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein movement along microtubule to cell tip cortex during vegetative growth" EXACT [PomBase:vw] synonym: "normal protein transport along microtubule to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein transport along microtubule to cell tip cortex during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005828 ! normal protein transport along microtubule to cell tip during vegetative growth is_a: FYPO:0006876 ! normal protein localization to cell cortex of cell tip created_by: midori creation_date: 2016-12-12T15:26:57Z [Term] id: FYPO:0005842 name: normal protein localization to interphase microtubule alt_id: FYPO:0005856 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a cytoplasmic microtubule is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cytoplasmic microtubule during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localisation to interphase microtubule" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic microtubule during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to interphase cytoplasmic microtubule" EXACT [PomBase:mah] synonym: "normal protein localization to interphase microtubule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to interphase microtubule during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2016-12-12T15:32:31Z [Term] id: FYPO:0005843 name: abolished histone H3-K9 trimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at centromere outer repeat region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3-K9 trimethylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone H3K9me3 at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "histone H3-K9 trimethylation abolished at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 trimethylation absent at centromere outer repeat during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000885 ! abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth created_by: midori creation_date: 2016-12-12T15:38:11Z [Term] id: FYPO:0005844 name: abolished histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me3 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished silent mating-type cassette histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 trimethylation abolished at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation during vegetative growth is_a: FYPO:0007373 ! abnormal histone methylation at silent mating-type cassette during vegetative growth created_by: midori creation_date: 2016-12-12T15:41:46Z [Term] id: FYPO:0005845 name: decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me3 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "decreased silent mating-type cassette histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000882 ! decreased histone H3-K9 trimethylation during vegetative growth is_a: FYPO:0007373 ! abnormal histone methylation at silent mating-type cassette during vegetative growth created_by: midori creation_date: 2016-12-12T15:45:03Z [Term] id: FYPO:0005846 name: abnormal histone methyltransferase activity (H3-K9 specific) activity def: "A molecular function phenotype in which the observed rate of H3-K9 specific histone methyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal H3-K9 specific histone methyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2016-12-12T15:48:30Z [Term] id: FYPO:0005847 name: decreased histone methyltransferase activity (H3-K9 specific) activity def: "A molecular function phenotype in which the observed rate of H3-K9 specific histone methyltransferase activity is decreased." [PomBase:mah] synonym: "decreased H3-K9 specific histone methyltransferase activity" EXACT [PomBase:mah] synonym: "reduced histone methyltransferase activity (H3-K9 specific) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0005846 ! abnormal histone methyltransferase activity (H3-K9 specific) activity created_by: midori creation_date: 2016-12-12T15:48:39Z [Term] id: FYPO:0005848 name: abolished histone methyltransferase activity (H3-K9 specific) activity def: "A molecular function phenotype in which H3-K9 specific histone methyltransferase activity is absent." [PomBase:mah] synonym: "abolished H3-K9 specific histone methyltransferase activity" EXACT [PomBase:mah] synonym: "histone methyltransferase activity (H3-K9 specific) activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0005846 ! abnormal histone methyltransferase activity (H3-K9 specific) activity created_by: midori creation_date: 2016-12-12T15:48:39Z [Term] id: FYPO:0005849 name: decreased spatial extent of heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a smaller portion of the chromosome than normal." [GO:0031507, PMID:27648579, PomBase:mah] synonym: "decreased heterochromatin spreading" RELATED [PomBase:mah] synonym: "decreased spatial extent of heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spatial extent of heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spatial extent of heterochromatin formation" EXACT [GO:0031507] synonym: "reduced spatial extent of heterochromatin assembly" EXACT [PomBase:mah] is_a: FYPO:0003044 ! abnormal heterochromatin assembly created_by: midori creation_date: 2016-12-12T15:57:56Z [Term] id: FYPO:0005850 name: abolished protein localization to heterochromatin at centromere outer repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions does not occur." [PMID:27648579, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "abolished protein localisation to heterochromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "abolished protein localization at centromere otr" EXACT [PomBase:mah] synonym: "abolished protein localization at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "abolished protein localization at pericentric region" RELATED [PomBase:mah] synonym: "abolished protein localization at pericentromeric region" RELATED [PomBase:mah] synonym: "abolished protein localization to centromere outer repeat heterochromatin" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere otr" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at centromeric outer repeat" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at pericentric region" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at pericentromeric region" RELATED [PomBase:mah] synonym: "abolished protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to heterochromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to heterochromatin at centromere outer repeat abolished" EXACT [PomBase:mah] is_a: FYPO:0003074 ! abolished protein localization to pericentric heterochromatin during vegetative growth created_by: midori creation_date: 2016-12-12T16:02:30Z [Term] id: FYPO:0005851 name: abnormal protein biotinylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biotinylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein biotinylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2016-12-12T16:13:02Z [Term] id: FYPO:0005852 name: decreased protein biotinylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biotinylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein biotinylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein biotinylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000545 ! decreased protein modification during vegetative growth is_a: FYPO:0005851 ! abnormal protein biotinylation during vegetative growth created_by: midori creation_date: 2016-12-12T16:13:17Z [Term] id: FYPO:0005853 name: aggregated filamentous actin in cytoplasm def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which filamentous actin (F-actin) is present in the cytoplasm in the form of dense, irregularly shaped aggregates." [PMID:12764130, PomBase:mah] synonym: "aggregated cytoplasmic F-actin" EXACT [PomBase:mah] synonym: "aggregated cytoplasmic filamentous actin" EXACT [PomBase:mah] synonym: "aggregated F- actin in cytoplasm" EXACT [PomBase:mah] synonym: "aggregated filamentous actin in cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "aggregated filamentous actin in cytoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "F-actin accumulation in cytoplasm" RELATED [PomBase:vw] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology during vegetative growth created_by: midori creation_date: 2016-12-12T16:22:53Z [Term] id: FYPO:0005854 name: increased actin cable assembly def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin cables is increased." [PMID:12764130, PomBase:mah] synonym: "actin bundling increased" RELATED [PomBase:vw] synonym: "increased actin bundling" RELATED [PomBase:vw] synonym: "increased actin cable assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased actin cable assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased formin-nucleated actin cable assembly" EXACT [GO:0070649] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth is_a: FYPO:0002030 ! abnormal actin cable organization created_by: midori creation_date: 2016-12-12T16:27:37Z [Term] id: FYPO:0005855 name: inviable after spore germination, single cell division, multiseptate cell def: "A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division to produce daughter cells that have two or more septa apiece, which then die." [PMID:12764130, PomBase:jh, PomBase:mah, PomBase:vw] synonym: "inviable following spore germination, single cell division, multiseptate cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, single cell division, multiseptate cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, single cell division, multiseptate cell" EXACT [PomBase:mah] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0002280 ! inviable after spore germination, single cell division relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2016-12-12T16:33:06Z [Term] id: FYPO:0005857 name: altered antisense RNA level during vegetative growth def: "A cell phenotype in which the amount of antisense RNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total antisense RNA or a specific antisense RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal antisense RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered antisense RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered antisense RNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "altered cellular antisense RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2016-12-15T14:54:37Z [Term] id: FYPO:0005858 name: altered level of translation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more translation RNAs measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells). Translation RNAs are transcribed from genes whose products are involved in translation." [PMID:26942678, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "abnormal level of translation gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of translation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered level of translation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of translation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "altered translation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2016-12-15T14:56:50Z [Term] id: FYPO:0005859 name: multiple Mei2 nuclear dots present in cell def: "A cell phenotype in which the cell contains two or more detectable Mei2 nuclear dot complexes instead of one." [PMID:26942678, PomBase:mah] synonym: "multiple Mei2 dots present in cell" EXACT [PomBase:vw] synonym: "multiple Mei2 nuclear dot complexes present in cell" EXACT [GO:0033620] synonym: "multiple Mei2 nuclear dots present in cell during meiotic cell cycle" EXACT [PomBase:mah] synonym: "multiple meiRNA nuclear dots present in cell" RELATED [PMID:24920274, PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2016-12-15T15:40:02Z [Term] id: FYPO:0005860 name: Mei2 nuclear dot present in cell during vegetative growth def: "A cell phenotype in which the cell contains a detectable Mei2 nuclear dot complex during the vegetative growth phase of the life cycle. Normally the Mei2 nuclear dot is only present during the meiotic cell cycle." [PMID:26942678, PomBase:mah] synonym: "Mei2 nuclear dot present in cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2016-12-15T15:43:04Z [Term] id: FYPO:0005861 name: abolished CCR4-NOT complex binding def: "A molecular function phenotype in which CCR4-NOT complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:26942678, PomBase:mah] synonym: "CCR4-NOT complex binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2016-12-15T15:52:37Z [Term] id: FYPO:0005862 name: abolished MTREC complex binding def: "A molecular function phenotype in which MTREC complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:26942678, PomBase:mah] synonym: "abolished NURS complex binding" EXACT [GO:1990477] synonym: "MTREC complex binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2016-12-15T16:06:09Z [Term] id: FYPO:0005863 name: loss of punctate nuclear protein localization def: "A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished punctate nuclear protein localization" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localisation" EXACT [PomBase:mah] synonym: "loss of punctate nuclear protein localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "loss of punctate nuclear protein localization during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear dots absent" RELATED [PomBase:mah] is_a: FYPO:0002624 ! decreased punctate nuclear protein localization created_by: midori creation_date: 2016-12-15T16:11:28Z [Term] id: FYPO:0005864 name: normal histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 in subtelomeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 methylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 methylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal subtelomeric histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2016-12-15T16:16:13Z [Term] id: FYPO:0005865 name: normal histone H3-K9 methylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 in silent mating-type cassettes is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 methylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 methylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9me at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "normal silent mating-type cassette histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2016-12-15T16:19:23Z [Term] id: FYPO:0005866 name: normal histone H3-K9 methylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 at ribosomal DNA is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 methylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 methylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K9me at rDNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2016-12-15T16:20:15Z [Term] id: FYPO:0005867 name: decreased histone H3-K9 dimethylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 at ribosomal DNA occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at rDNA during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at rDNA during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at rDNA during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at rDNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2016-12-15T16:23:14Z [Term] id: FYPO:0005868 name: increased mitotic recombination at rDNA def: "A cellular process phenotype in which the occurrence of mitotic recombination is increased at ribosomal DNA." [PomBase:mah] synonym: "increased mitotic recombination at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitotic recombination at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitotic recombination at ribosomal DNA" EXACT [PomBase:mah] is_a: FYPO:0000473 ! increased mitotic recombination created_by: midori creation_date: 2016-12-15T16:25:01Z [Term] id: FYPO:0005869 name: inviable stubby multiseptate vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable and has one nucleus and more than one septum, and the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable stubby multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable stubby multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable watermelon-shaped multiseptate vegetative cell" EXACT [PomBase:mah] synonym: "lethal; stubby multiseptate vegetative cell" EXACT [PomBase:mah] synonym: "stubby multiseptate inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0002200 ! inviable stubby septated vegetative cell relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2016-12-15T16:29:01Z [Term] id: FYPO:0005870 name: incomplete septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that does not completely bisect the cell." [PMID:21931816, PomBase:mah] synonym: "discontinuous septum" EXACT [PomBase:mah] synonym: "incomplete septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "incomplete septum during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete septum structure" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2016-12-15T16:32:37Z [Term] id: FYPO:0005871 name: thin, incomplete primary cell septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a primary septum that is thinner than normal and does not extend over the entire cell division site." [PMID:27898700, PomBase:mah] synonym: "incomplete primary cell septum with decreased thickness" EXACT [PomBase:mah] synonym: "incomplete primary cell septum with reduced thickness" EXACT [PomBase:mah] synonym: "thin, discontinuous primary septum" EXACT [PMID:27898700] synonym: "thin, incomplete primary cell septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "thin, incomplete primary cell septum during vegetative growth" EXACT [PomBase:mah] synonym: "thin, incomplete primary septum" EXACT [PomBase:mah] is_a: FYPO:0003205 ! decreased primary cell septum thickness is_a: FYPO:0005870 ! incomplete septum relationship: has_part FYPO:0003205 ! decreased primary cell septum thickness created_by: midori creation_date: 2016-12-15T16:35:08Z [Term] id: FYPO:0005872 name: incomplete septum formed from asymmetrically located sites def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the septum is in two asymmetrically located parts and does not completely bisect the cell. Arises when septum assembly begins at two sites which are not on opposite sides of the medial cortex and terminates prematurely on both sides." [PMID:27898700, PomBase:mah] comment: Consider also annotating to 'abnormal contractile ring localization' (FYPO:0000033) because if the contractile ring forms in an abnormal location, the septum will also do so. The positions of both the contractile ring and the septum are determined by the processes that select the site of cell division. synonym: "abnormal septum site selection from asymmetrically located sites, forming incomplete septum" RELATED [PomBase:mah] synonym: "incomplete division septum formed from asymmetrically located sites" EXACT [PomBase:mah] synonym: "incomplete septum formed from asymmetrically located sites during mitotic cell cycle" RELATED [PomBase:mah] synonym: "incomplete septum formed from asymmetrically located sites during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000339 ! mislocalized septum during vegetative growth is_a: FYPO:0005870 ! incomplete septum created_by: midori creation_date: 2016-12-15T16:43:32Z [Term] id: FYPO:0005873 name: increased secondary cell septum thickness def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thicker than normal." [PomBase:mah] synonym: "increased secondary cell septum thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased secondary cell septum thickness during vegetative growth" EXACT [PomBase:mah] synonym: "increased secondary septum thickness" EXACT [PomBase:mah] synonym: "thick secondary septum" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth relationship: output_of FYPO:0003211 ! abnormal secondary cell septum biogenesis created_by: midori creation_date: 2016-12-15T16:47:49Z [Term] id: FYPO:0005874 name: decreased rate of medial membrane band assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of medial membrane band assembly is decreased. Medial membrane band assembly is the assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring." [GO:0032130, PomBase:mah] synonym: "decreased rate of medial membrane band assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of medial membrane band assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of medial membrane band formation" EXACT [GO:0032130, PomBase:mah] synonym: "reduced rate of medial membrane band assembly" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis during vegetative growth created_by: midori creation_date: 2016-12-16T14:05:27Z [Term] id: FYPO:0005875 name: growth auxotrophic for proline def: "Auxotrophy in which a cell is unable to synthesize proline, and therefore requires proline in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for proline during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for proline during vegetative growth" EXACT [PomBase:mah] synonym: "proline auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2016-12-21T13:48:26Z [Term] id: FYPO:0005876 name: growth auxotrophic for tyrosine def: "Auxotrophy in which a cell is unable to synthesize tyrosine, and therefore requires tyrosine in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for tyrosine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for tyrosine during vegetative growth" EXACT [PomBase:mah] synonym: "tyrosine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2016-12-21T13:50:29Z [Term] id: FYPO:0005877 name: growth auxotrophic for glutamate def: "Auxotrophy in which a cell is unable to synthesize glutamate, and therefore requires glutamate in the medium for vegetative cell growth." [PomBase:mah] synonym: "glutamate auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for glutamate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for glutamate during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for glutamic acid" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2016-12-21T13:51:03Z [Term] id: FYPO:0005878 name: growth auxotrophic for tryptophan def: "Auxotrophy in which a cell is unable to synthesize tryptophan, and therefore requires tryptophan in the medium for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for tryptophan during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for tryptophan during vegetative growth" EXACT [PomBase:mah] synonym: "tryptophan auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2016-12-21T13:51:43Z [Term] id: FYPO:0005879 name: C-shaped interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are curved to form a \"C\" shape, i.e. they follow a smooth bend rather than a straight line, with the curve centered at or near the midpoint of the microtubule, during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "C-shaped cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "C-shaped interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "C-shaped interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "C-shaped interphase microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "curved C-shaped interphase microtubules" EXACT [PomBase:mah] is_a: FYPO:0003327 ! curved interphase microtubules created_by: midori creation_date: 2017-01-11T11:07:04Z [Term] id: FYPO:0005880 name: long interphase microtubules curved around cell end def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal and are curved, i.e. follow a smooth bend rather than a straight line, and extend around one or both ends of the cell, during interphase of the mitotic cell cycle." [PMID:14663827, PomBase:mah] synonym: "elongated interphase microtubules curved around cell end" EXACT [PomBase:mah] synonym: "long cytoplasmic microtubules curved around cell end during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "long cytoplasmic microtubules curved around cell end during mitotic interphase" EXACT [PomBase:mah] synonym: "long interphase cytoplasmic microtubules curved around cell end" EXACT [PomBase:mah] synonym: "long interphase microtubules curved around cell end during vegetative growth" EXACT [PomBase:mah] synonym: "long interphase microtubules curved around cell tip" EXACT [PomBase:mah] is_a: FYPO:0004511 ! long curved interphase microtubules created_by: midori creation_date: 2017-01-11T11:11:21Z [Term] id: FYPO:0005881 name: ophthalmic acid absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ophthalmic acid measured in a cell is too low to detect." [PomBase:mah] synonym: "ophthalmic acid absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "ophthalmic acid absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth created_by: midori creation_date: 2017-01-11T13:23:22Z [Term] id: FYPO:0005882 name: increased cellular gamma-glutamyl-2-aminobutyrate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of gamma-glutamyl-2-aminobutyrate (also called gamma-Glu-Abu) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular gamma-Glu-Abu level" RELATED [CHEBI:133092, PomBase:mah] synonym: "increased cellular gamma-Glu-Abu(1-) level" EXACT [CHEBI:133093] synonym: "increased cellular gamma-glutamyl-2-aminobutyrate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular gamma-glutamyl-2-aminobutyrate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased gamma-glutamyl-2-aminobutyrate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-01-11T13:42:21Z [Term] id: FYPO:0005883 name: abolished anaerobic cell population growth def: "A vegetative cell population growth phenotype in which a cell population does not grow under anaerobic conditions." [PomBase:mah] comment: Use this term for a population of cells that does not grow under anaerobic conditions, but does grow under aerobic or semi-aerobic conditions (a cell population that does not grow at any oxygen level would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished anaerobic vegetative cell population growth" EXACT [PomBase:mah] synonym: "anaerobic cell population growth abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2017-01-11T13:45:58Z [Term] id: FYPO:0005884 name: normal growth on myxothiazol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing myxothiazol." [PomBase:mah] synonym: "normal cell population growth in presence of myxothiazol" EXACT [PomBase:mah] synonym: "normal cell population growth on MXT" EXACT [PomBase:al] synonym: "normal cell population growth on myxothiazol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on myxothiazol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2017-01-11T13:49:08Z [Term] id: FYPO:0005885 name: sensitive to myxothiazol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to myxothiazol. Cells stop growing (and may die) at a concentration of myxothiazol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to myxothiazol" EXACT [PomBase:mah] synonym: "sensitive to MXT" EXACT [PomBase:al] synonym: "sensitive to myxothiazol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to myxothiazol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-01-11T13:50:03Z [Term] id: FYPO:0005886 name: increased transcription from HSE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more heat shock elements (HSEs) occurs to a greater extent than normal." [PomBase:mah] synonym: "expression of Hsf1 target genes increased" RELATED [PomBase:mah] synonym: "increased transcription from HSE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from HSE promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2017-01-11T14:01:06Z [Term] id: FYPO:0005887 name: ectopic CENP-A containing chromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled in one or more regions of the chromosome away from the centromere. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions." [GO:0034080, PMID:27666591, PomBase:mah, PomBase:vw] synonym: "CENP-A containing nucleosome assembly away from centromere" EXACT [PomBase:mah] synonym: "ectopic CenH3-containing nucleosome assembly at centromere" RELATED [GO:0034080] synonym: "ectopic CENP-A containing nucleosome assembly" RELATED [] synonym: "ectopic CENP-A containing nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "ectopic CENP-A containing nucleosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "ectopic CENP-A deposition" RELATED [GO:0034080] synonym: "ectopic CENP-A loading" RELATED [GO:0034080] synonym: "ectopic centromere-specific histone exchange" EXACT [GO:0034080] synonym: "ectopic centromere-specific nucleosome assembly" EXACT [GO:0034080] synonym: "ectopic centromeric DNA replication-independent nucleosome assembly" EXACT [GO:0034080] synonym: "multiple foci of CENP-A" RELATED [PomBase:vw] is_a: FYPO:0003409 ! abnormal CENP-A containing chromatin assembly created_by: midori creation_date: 2017-01-11T14:07:46Z [Term] id: FYPO:0005888 name: decreased protein localization to centromeric chromatin, with protein mislocalized to nucleoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased, and some of the protein is present in the nucleoplasm instead." [PMID:27666591, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromeric chromatin, with protein mislocalised to nucleoplasm" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin, with protein mislocalized to nucleoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin, with protein mislocalized to nucleoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere, with protein mislocalized to nucleoplasm" EXACT [PomBase:mah] synonym: "reduced protein localization to centromeric chromatin, with protein mislocalized to nucleoplasm" EXACT [PomBase:mah] is_a: FYPO:0002843 ! protein mislocalized to nucleoplasm is_a: FYPO:0006599 ! decreased protein localization to centromeric chromatin during vegetative growth relationship: has_part FYPO:0002843 ! protein mislocalized to nucleoplasm created_by: midori creation_date: 2017-01-11T14:31:45Z [Term] id: FYPO:0005889 name: sensitive to sodium chloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium chloride. Cells stop growing (and may die) at a concentration of sodium chloride that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium chloride" EXACT [PomBase:mah] synonym: "sensitive to NaCl" EXACT [PomBase:mah] synonym: "sensitive to sodium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium chloride during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-01-11T14:36:36Z [Term] id: FYPO:0005890 name: normal protein localization to nucleus during cellular response to calcium ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to calcium ions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during cellular response to calcium ion" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to calcium" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to calcium ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to calcium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2017-01-11T14:38:03Z [Term] id: FYPO:0005891 name: decreased nuclease activity during nitrogen starvation def: "A molecular function phenotype in which the observed rate of a nuclease activity is decreased when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased nuclease activity during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased nuclease activity during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced nuclease activity during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0004253 ! decreased nuclease activity created_by: midori creation_date: 2017-01-11T14:46:19Z [Term] id: FYPO:0005892 name: increased RNA catabolic process during nitrogen starvation def: "A cellular process phenotype in which the occurrence of an RNA catabolic process is increased when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "increased RNA breakdown during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased RNA catabolic process during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased RNA catabolic process during nitrogen deprivation" RELATED [PomBase:mah] synonym: "increased RNA catabolism during nitrogen starvation" EXACT [GO:0006401] synonym: "increased RNA degradation during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0003553 ! increased RNA catabolic process created_by: midori creation_date: 2017-01-11T14:50:41Z [Term] id: FYPO:0005893 name: increased protein level in chromatin def: "A cell phenotype in which the amount of protein found associated with chromatin is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein level at chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level in chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level in chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "protein accumulation in chromatin" EXACT [PomBase:vw] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2017-01-16T15:08:45Z [Term] id: FYPO:0005894 name: normal protein localization to chromatin during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin during mitotic G1 phase" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2017-01-17T12:20:26Z [Term] id: FYPO:0005895 name: decreased protein localization to centromeric chromatin during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromeric chromatin during mitotic G1 phase" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to centromeric chromatin during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0005896 ! decreased protein localization to chromatin during mitotic G1 phase is_a: FYPO:0006599 ! decreased protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2017-01-17T12:23:11Z [Term] id: FYPO:0005896 name: decreased protein localization to chromatin during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin during mitotic G1 phase" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to chromatin during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2017-01-17T12:26:54Z [Term] id: FYPO:0005897 name: increased protein localization to chromatin during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin during mitotic G1 phase" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2017-01-17T12:46:04Z [Term] id: FYPO:0005898 name: increased protein localization to centromeric chromatin during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is increased during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromeric chromatin during mitotic G1 phase" EXACT [PomBase:mah] synonym: "increased protein localization to centromeric chromatin during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to centromeric chromatin during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005306 ! abnormal protein localization to centromeric chromatin during vegetative growth is_a: FYPO:0005897 ! increased protein localization to chromatin during mitotic G1 phase created_by: midori creation_date: 2017-01-17T12:46:14Z [Term] id: FYPO:0005899 name: normal rate of actin filament-based movement def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament-based movement is normal (i.e. indistinguishable from wild type). Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GO:0030048, PMID:19570908, PomBase:mah] synonym: "normal rate of actin filament-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of actin filament-based movement during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2017-01-17T13:21:37Z [Term] id: FYPO:0005900 name: abnormal actin filament-based movement def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament-based movement is abnormal. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GO:0030048, PMID:19570908, PomBase:mah] synonym: "abnormal actin filament-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin filament-based movement during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2017-01-17T13:25:45Z [Term] id: FYPO:0005901 name: increased rate of actin filament-based movement def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament-based movement is increased. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GO:0030048, PMID:19570908, PomBase:mah] synonym: "increased rate of actin filament-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of actin filament-based movement during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005900 ! abnormal actin filament-based movement created_by: midori creation_date: 2017-01-17T13:27:47Z [Term] id: FYPO:0005902 name: decreased rate of actin filament-based movement def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament-based movement is decreased. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GO:0030048, PMID:19570908, PomBase:mah] synonym: "decreased rate of actin filament-based movement during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actin filament-based movement during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of actin filament-based movement" EXACT [PomBase:mah] is_a: FYPO:0005900 ! abnormal actin filament-based movement created_by: midori creation_date: 2017-01-17T13:28:49Z [Term] id: FYPO:0005903 name: incomplete actomyosin contractile ring contraction def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins, but stops before the ring completely constricts and is disassembled." [PMID:19570908, PomBase:mah] synonym: "incomplete actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "incomplete actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2017-01-17T13:30:09Z [Term] id: FYPO:0005904 name: normal rate of protein exchange in actomyosin contractile ring def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type). Normally, proteins including actin and myosin are turned over between the contractile ring and elsewhere in the cytoplasm; exchange is faster during than before ring constriction." [PMID:19570908, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal rate of protein exchange in actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of protein exchange in actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2017-01-17T13:34:20Z [Term] id: FYPO:0005905 name: normal onset of actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PMID:19570908, PomBase:mah] synonym: "normal onset of actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal onset of actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal onset of actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:vw] synonym: "normal onset of contractile ring assembly" EXACT [PomBase:mah] synonym: "normal onset of cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "normal onset of cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "normal onset of cytokinetic ring formation" RELATED [PomBase:vw] synonym: "normal onset of mitotic contractile ring assembly" EXACT [PomBase:vw] synonym: "normal timing of actomyosin contractile ring assembly" RELATED [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2017-01-17T13:44:54Z [Term] id: FYPO:0005906 name: normal onset of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cgontractile ring contraction begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PMID:19570908, PomBase:mah] synonym: "normal dwell time before actomyosin contractile ring contraction" EXACT [PomBase:mah] synonym: "normal onset of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal onset of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "normal onset of contractile ring contraction" EXACT [PomBase:mah] synonym: "normal onset of cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "normal onset of cytokinetic ring contraction" RELATED [PomBase:vw] synonym: "normal onset of mitotic contractile ring contraction" EXACT [PomBase:vw] synonym: "normal timing of actomyosin contractile ring contraction" RELATED [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2017-01-17T14:00:11Z [Term] id: FYPO:0005907 name: normal protein localization to nucleus during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to heat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during cellular response to heat" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2017-01-18T13:52:53Z [Term] id: FYPO:0005908 name: decreased level of stress responsive gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell is lower than normal (i.e. lower than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased level of cellular response to stress gene mRNA during vegetative growth" EXACT [PomBase:al] synonym: "decreased level of stress responsive gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of stress responsive gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of stress responsive gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased mRNA level of stress responsive genes during vegetative growth" EXACT [PomBase:al] synonym: "decreased stress responsive gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced level of stress responsive gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0004363 ! altered level of stress responsive gene mRNA during vegetative growth created_by: midori creation_date: 2017-01-18T13:55:15Z [Term] id: FYPO:0005909 name: abnormal RNA 3'-end processing during cellular response to endoplasmic reticulum stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an RNA molecule is abnormal during a cellular response to endoplasmic reticulum stress." [GO:0031123, PMID:23066505, PomBase:mah] synonym: "abnormal RNA 3'-end processing during cellular response to endoplasmic reticulum stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal RNA 3'-end processing during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal RNA 3'-end processing during cellular response to ER stress" EXACT [PomBase:mah] is_a: FYPO:0007918 ! abnormal RNA 3'-end processing created_by: midori creation_date: 2017-01-23T15:16:31Z [Term] id: FYPO:0005910 name: decreased protein level during cellular response to endoplasmic reticulum stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to endoplasmic reticulum stress is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to endoplasmic reticulum stress" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to endoplasmic reticulum stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to ER stress" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to endoplasmic reticulum stress" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2017-01-23T15:19:33Z [Term] id: FYPO:0005911 name: delayed onset of meiotic recombination double-strand break repair def: "A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination begins later than normal." [PMID:19023408, PomBase:mah] synonym: "delayed meiotic recombination double-strand break repair" EXACT [PomBase:mah] synonym: "delayed onset of double-strand break repair during meiotic recombination" EXACT [PomBase:mah] synonym: "delayed onset of double-strand break repair involved in reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "delayed onset of DSB repair involved in reciprocal meiotic recombination" EXACT [PomBase:vw] synonym: "delayed onset of meiotic DNA double-strand break repair" EXACT [PomBase:mah] is_a: FYPO:0005139 ! abnormal meiotic recombination double-strand break repair created_by: midori creation_date: 2017-02-01T14:46:59Z [Term] id: FYPO:0005912 name: normal meiosis-specific chromatin remodeling def: "A cellular process phenotype in which chromatin remodeling that occurs as part of meiosis I is normal (i.e. indistinguishable from wild type)." [GO:1905886, PMID:19139281, PomBase:mah] synonym: "normal chromatin remodeling during meiosis I" EXACT [PomBase:mah] synonym: "normal chromatin remodeling involved in meiosis I" EXACT [GO:1905886] synonym: "normal meiotic nuclear division-specific chromatin remodeling" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2017-02-01T14:50:11Z [Term] id: FYPO:0005913 name: abnormal chromatin remodeling during meiosis I def: "A cellular process phenotype in which chromatin remodeling that occurs as part of meiosis I is abnormal." [GO:1905886, PMID:19139281, PomBase:mah] synonym: "abnormal chromatin remodeling involved in meiosis I" EXACT [GO:1905886] synonym: "abnormal meiotic nuclear division-specific chromatin remodeling" EXACT [PomBase:mah] is_a: FYPO:0006356 ! abnormal chromatin remodeling is_a: FYPO:0007943 ! abnormal chromatin organization during meiotic cell cycle created_by: midori creation_date: 2017-02-01T14:52:47Z [Term] id: FYPO:0005914 name: elongated linear element def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form linear element that are longer than normal." [PMID:19139281, PomBase:mah] synonym: "increased linear element length" EXACT [PomBase:mah] synonym: "long linear element" EXACT [PomBase:mah] is_a: FYPO:0004585 ! abnormal linear element morphology created_by: midori creation_date: 2017-02-01T14:55:49Z [Term] id: FYPO:0005915 name: decreased nucleosome occupancy at 5S rRNA genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at the portion of ribosomal DNA encoding 5S rRNA. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:25798942, PomBase:mah] synonym: "decreased nucleosome occupancy at 5S rRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at 5S rRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy in 5S rRNA genes" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at 5S rRNA genes" EXACT [PomBase:mah] is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: midori creation_date: 2017-02-01T15:06:27Z [Term] id: FYPO:0005916 name: decreased nucleosome occupancy at tRNA genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at tRNA genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:25798942, PomBase:mah] synonym: "decreased nucleosome occupancy at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at tRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy in tRNA genes" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at tRNA genes" EXACT [PomBase:mah] is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: midori creation_date: 2017-02-01T15:08:48Z [Term] id: FYPO:0005917 name: increased subtelomeric heterochromatin RNA level def: "A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin regions is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:25798942] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "accumulation of subtelomere-derived RNA transcripts" RELATED [] synonym: "increased transcription at subtelomere" NARROW [] synonym: "increased transcription at subtelomeric heterochromatin during vegetative growth" NARROW [] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0002875 ! increased transcription created_by: midori creation_date: 2017-02-01T15:10:38Z [Term] id: FYPO:0005918 name: decreased protein localization to subtelomeric heterochromatin def: "A cell phenotype the localization of a protein to heterochromatin in subtelomeric regions is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to subtelomeric heterochromatin" EXACT [PomBase:mah] synonym: "decreased protein localization to heterochromatin at subtelomere" EXACT [PomBase:mah] synonym: "decreased protein localization to telomeric heterochromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "reduced protein localization to subtelomeric heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2017-02-01T15:12:05Z [Term] id: FYPO:0005919 name: sensitive to TOP-53 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to TOP-53. Cells stop growing (and may die) at a concentration of TOP-53 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to TOP-53" EXACT [PomBase:mah] synonym: "sensitive to TOP-53 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to TOP-53 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-02-01T15:15:01Z [Term] id: FYPO:0005920 name: normal nucleosome occupancy at tRNA genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is normal (i.e. indistinguishable from wild type) at tRNA genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:21437270, PomBase:mah] synonym: "normal nucleosome occupancy at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleosome occupancy at tRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome occupancy in tRNA genes" EXACT [PomBase:mah] is_a: FYPO:0000856 ! normal nucleosome positioning created_by: midori creation_date: 2017-02-07T14:34:49Z [Term] id: FYPO:0005921 name: increased histone H4-K12 acetylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in centromere inner repeat regions occurs to a greater extent than normal." [PMID:21437270, PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "increased histone H4-K12 acetylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H4-K12 acetylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K12 acetylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0007631 ! increased histone H4-K12 acetylation during vegetative growth created_by: midori creation_date: 2017-02-07T14:39:20Z [Term] id: FYPO:0005922 name: decreased heterochromatin assembly at subtelomere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly occurs to a lower extent than normal in subtelomeric regions. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PMID:21437270, PomBase:mah] synonym: "decreased heterochromatin assembly at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased heterochromatin assembly at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased heterochromatin formation at subtelomere" EXACT [GO:0031507, PomBase:mah] synonym: "decreased subtelomeric heterochromatin assembly" EXACT [PomBase:mah] synonym: "reduced heterochromatin assembly at subtelomere" EXACT [PomBase:mah] is_a: FYPO:0004543 ! abnormal heterochromatin organization during vegetative growth is_a: FYPO:0006356 ! abnormal chromatin remodeling created_by: midori creation_date: 2017-02-07T14:44:54Z [Term] id: FYPO:0005923 name: increased H2A.Z level at subtelomere def: "A cell phenotype in which the amount of the histone variant H2A.Z found associated with chromatin in subtelomeric regions is higher than normal when the cell is in the vegetative growth phase of the life cycle." [PMID:21437270, PomBase:mah] synonym: "H2A.Z accumulation at subtelomere" EXACT [PomBase:vw] synonym: "increased H2A.Z level at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased H2A.Z level at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased H2A.Z level in chromatin at subtelomere" EXACT [PomBase:mah] is_a: FYPO:0005893 ! increased protein level in chromatin created_by: midori creation_date: 2017-02-07T14:58:25Z [Term] id: FYPO:0005924 name: increased H2A.Z level at centromere inner repeat def: "A cell phenotype in which the amount of the histone variant H2A.Z found associated with chromatin in centromere inner repeat regions is higher than normal when the cell is in the vegetative growth phase of the life cycle." [PMID:21437270, PomBase:mah] synonym: "H2A.Z accumulation at centromere inner repeat" EXACT [PomBase:vw] synonym: "increased H2A.Z level at centromere imr during vegetative growth" EXACT [PomBase:mah] synonym: "increased H2A.Z level at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased H2A.Z level at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased H2A.Z level in chromatin at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0005893 ! increased protein level in chromatin created_by: midori creation_date: 2017-02-07T15:02:09Z [Term] id: FYPO:0005925 name: normal protein level during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during mitosis" RELATED [PomBase:mah] synonym: "normal protein level during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during mitotic M phase" RELATED [PomBase:mah] synonym: "normal protein level during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2017-02-07T15:14:35Z [Term] id: FYPO:0005926 name: normal protein level during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during mitotic G1 phase" RELATED [PomBase:mah] synonym: "normal protein level during G1 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2017-02-07T15:20:48Z [Term] id: FYPO:0005927 name: normal protein monoubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the monoubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein monoubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein monoubiquitinylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein monoubiquitylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein/peptide monoubiquitination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2017-02-07T15:29:26Z [Term] id: FYPO:0005928 name: abolished protein polyubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the polyubiquitination of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein polyubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein polyubiquitinylation during vegetative growth" RELATED [GO:0000209, PomBase:mah] synonym: "abolished protein polyubiquitylation during vegetative growth" EXACT [GO:0000209, PomBase:mah] synonym: "protein polyubiquitination abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0000905 ! abnormal protein ubiquitination during vegetative growth created_by: midori creation_date: 2017-02-07T15:30:14Z [Term] id: FYPO:0005929 name: decreased chromatin binding at centromere outer repeat def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at the centromere outer repeat region is decreased." [PomBase:mah] synonym: "decreased chromatin binding at centromere otr" EXACT [PomBase:mah] synonym: "decreased chromatin binding at centromere outer repeat region" EXACT [PomBase:mah] synonym: "decreased chromatin binding at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "decreased chromatin binding at pericentric region" RELATED [PomBase:mah] synonym: "decreased chromatin binding at pericentromeric region" RELATED [PomBase:mah] synonym: "reduced chromatin binding at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2017-02-07T15:32:45Z [Term] id: FYPO:0005930 name: normal chromatin binding at centromere outer repeat def: "A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at the centromere outer repeat region." [PomBase:mah] synonym: "normal chromatin binding at centromere otr" EXACT [PomBase:mah] synonym: "normal chromatin binding at centromere outer repeat region" EXACT [PomBase:mah] synonym: "normal chromatin binding at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "normal chromatin binding at pericentric region" RELATED [PomBase:mah] synonym: "normal chromatin binding at pericentromeric region" RELATED [PomBase:mah] is_a: FYPO:0003086 ! normal chromatin binding created_by: midori creation_date: 2017-02-07T15:34:34Z [Term] id: FYPO:0005931 name: decreased nucleosome occupancy at silent mating-type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at the silent mating-type cassettes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:24662054, PomBase:mah] synonym: "decreased nucleosome occupancy at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy in silent mating-type cassette" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at silent mating-type cassette" EXACT [PomBase:mah] is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: midori creation_date: 2017-02-07T15:35:26Z [Term] id: FYPO:0005932 name: decreased nucleosome occupancy at long terminal repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at long terminal repeat (LTR) regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:25798942, PomBase:mah] synonym: "decreased nucleosome occupancy at long terminal repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at long terminal repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy at LTR" EXACT [PomBase:mah] synonym: "decreased nucleosome occupancy in long terminal repeat" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at long terminal repeat" EXACT [PomBase:mah] is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: midori creation_date: 2017-02-07T15:42:08Z [Term] id: FYPO:0005933 name: decreased protein level during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G1 phase of the mitotic cell cycle is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during mitotic G1 phase" RELATED [PomBase:mah] synonym: "decreased protein level during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein level during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2017-02-08T11:57:56Z [Term] id: FYPO:0005934 name: abolished protein sumoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the sumoylation of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein sumoylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein sumoylation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0002777 ! abnormal protein sumoylation during vegetative growth created_by: midori creation_date: 2017-02-20T14:45:49Z [Term] id: FYPO:0005935 name: normal meiotic recombination frequency def: "A cellular process phenotype in which the frequency of occurrence of meiotic recombination is normal (i.e. indistinguishable from wild type). Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes." [GO:0007131, PMID:19470480, PomBase:mah] synonym: "normal occurrence of meiotic recombination" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2017-02-20T15:13:46Z [Term] id: FYPO:0005936 name: normal intragenic meiotic recombination frequency def: "A cellular process phenotype in which the frequency of occurrence of intragenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intragenic meiotic recombination can result in gene conversion events." [PMID:19470480, PomBase:mah] synonym: "normal meiotic intragenic recombination frequency" EXACT [PomBase:al] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2017-02-20T15:18:45Z [Term] id: FYPO:0005937 name: decreased protein localization to chromatin at late replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at late replication origins is decreased." [PMID:24656819, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at late replication origin" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at late origin" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at late replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at late replication origins during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at late replication origin" EXACT [PomBase:mah] is_a: FYPO:0003950 ! decreased protein localization to chromatin at replication origin created_by: midori creation_date: 2017-02-20T15:33:06Z [Term] id: FYPO:0005938 name: normal protein localization to chromatin at late replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at late replication origins is normal (i.e. indistinguishable from wild type)." [PMID:24656819, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at late replication origin" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at late origin" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at late replication origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at late replication origin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004962 ! normal protein localization to chromatin at replication origin created_by: midori creation_date: 2017-02-20T15:35:46Z [Term] id: FYPO:0005939 name: decreased replicative lifespan def: "A cell population phenotype in which the replicative lifespan of a cell population, i.e. the number of divisions cells in the population undergo before death, is lower than normal." [PMID:28139976, PomBase:mah] comment: Although each cell has a replicative lifespan in that it divides a certain number of times and then dies, replicative lifespan is often measured at the population level, where it is defined by the number of generations at which 50% of the starting cells are dead. synonym: "decreased cell population replicative lifespan" EXACT [PomBase:mah] synonym: "decreased population replicative lifespan" EXACT [PomBase:mah] synonym: "reduced replicative lifespan" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2017-02-20T16:04:56Z [Term] id: FYPO:0005940 name: increased replicative lifespan def: "A cell population phenotype in which the replicative lifespan of a cell population, i.e. the number of divisions cells in the population undergo before death, is higher than normal." [PMID:28139976, PomBase:mah] comment: Although each cell has a replicative lifespan in that it divides a certain number of times and then dies, replicative lifespan is often measured at the population level, where it is defined by the number of generations at which 50% of the starting cells are dead. synonym: "increased cell population replicative lifespan" EXACT [PomBase:mah] synonym: "increased population replicative lifespan" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2017-02-20T16:06:55Z [Term] id: FYPO:0005941 name: normal meiotic DNA double-strand break clipping def: "A cellular process phenotype in which meiotic DNA double-strand break clipping is normal (i.e. indistinguishable from wild type). Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis." [GO:1990898, PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2017-03-09T14:34:21Z [Term] id: FYPO:0005942 name: normal intergenic meiotic recombination frequency def: "A cellular process phenotype in which the frequency of occurrence of intergenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intergenic meiotic recombination reflects crossovers between homologous chromosomes." [PMID:19752195, PomBase:mah] synonym: "normal meiotic intergenic recombination frequency" EXACT [PomBase:al] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2017-03-09T14:49:08Z [Term] id: FYPO:0005943 name: decreased break-induced loss of heterozygosity via chromosomal translocation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal translocation that would result in the loss of one of two different alleles of a gene occurs to a lower extent than normal." [PMID:19798055, PomBase:mah] comment: This phenotype may be observed in diploid cells, or in cells that have two copies of one or more reporter loci but are otherwise haploid. Loss of heterozygosity associated with chromosomal translocation may result from allelic crossover or break-induced replication. In cells with this phenotype, loss of heterozygosity may or may not occur via a different mechanism, such as chromosomal truncation. synonym: "decreased break-induced loss of heterozygosity via chromosomal translocation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased break-induced loss of heterozygosity via chromosomal translocation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced break-induced loss of heterozygosity via chromosomal translocation" EXACT [PomBase:mah] is_a: FYPO:0005451 ! decreased break-induced loss of heterozygosity created_by: midori creation_date: 2017-03-09T15:01:56Z [Term] id: FYPO:0005944 name: increased break-induced loss of heterozygosity via chromosomal truncation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal truncation that would result in the loss of one of two different alleles of a gene occurs to a greater extent than normal." [PMID:19798055, PomBase:mah] comment: This phenotype may be observed in diploid cells, or in cells that have two copies of one or more reporter loci but are otherwise haploid. Loss of heterozygosity associated with chromosomal translocation may result from allelic crossover or break-induced replication. In cells with this phenotype, loss of heterozygosity may or may not occur via a different mechanism, such as chromosomal truncation. synonym: "increased break-induced loss of heterozygosity via chromosomal truncation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased break-induced loss of heterozygosity via chromosomal truncation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005452 ! increased break-induced loss of heterozygosity is_a: FYPO:0007424 ! increased chromosomal truncation created_by: midori creation_date: 2017-03-09T15:04:12Z [Term] id: FYPO:0005945 name: normal frequency of break-induced loss of heterozygosity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal truncation that would result in the loss of one of two different alleles of a gene occurs at a normal (i.e. indistinguishable from wild type) frequency." [PMID:19798055, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-03-09T15:08:26Z [Term] id: FYPO:0005946 name: decreased level of cell cycle regulated gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell cycle-regulated mRNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cell cycle-regulated mRNAs are transcribed from genes whose level of transcription varies depending on cell cycle phase." [PMID:15195092, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased cell cycle regulated gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased level of cell cycle regulated gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of cell cycle regulated gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of cell cycle regulated gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "decreased level of cell cycle-regulated gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of cell cycle regulated gene mRNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2017-03-09T15:17:59Z [Term] id: FYPO:0005947 name: normal growth on potassium chloride def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing potassium chloride." [PomBase:mah] synonym: "normal cell population growth in presence of potassium chloride" EXACT [PomBase:mah] synonym: "normal cell population growth on KCl" EXACT [PomBase:mah] synonym: "normal cell population growth on potassium chloride" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to potassium chloride" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on potassium chloride" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2017-03-15T16:00:11Z [Term] id: FYPO:0005948 name: decreased protein localization to chromatin at highly transcribed RNA polymerase II genes during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin regions where RNA polymerase II actively transcribes genes is decreased." [PMID:28218250, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at polymerase II highly transcribed genes during vegetative growth" EXACT [PomBase:vw] synonym: "reduced protein localization to chromatin at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004161 ! decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth created_by: midori creation_date: 2017-03-15T16:05:50Z [Term] id: FYPO:0005949 name: normal protein localization to chromatin at highly transcribed RNA polymerase II genes during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin regions where RNA polymerase II actively transcribes genes is normal (i.e. indistinguishable from wild type)." [PMID:28218250, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at polymerase II highly transcribed genes during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0007536 ! normal protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth created_by: midori creation_date: 2017-03-15T16:09:21Z [Term] id: FYPO:0005950 name: increased nucleosome occupancy at highly transcribed RNA polymerase II genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal in chromatin regions where RNA polymerase II actively transcribes genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:28218250, PomBase:mah] synonym: "increased nucleosome occupancy at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000854 ! abnormal nucleosome positioning in euchromatin created_by: midori creation_date: 2017-03-15T16:12:25Z [Term] id: FYPO:0005951 name: decreased nucleosome occupancy at highly transcribed RNA polymerase II genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in chromatin regions where RNA polymerase II actively transcribes genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:28218250, PomBase:mah] synonym: "decreased nucleosome occupancy at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at highly transcribed RNA polymerase II genes" EXACT [PomBase:mah] is_a: FYPO:0005516 ! decreased nucleosome occupancy in euchromatin created_by: midori creation_date: 2017-03-15T16:14:10Z [Term] id: FYPO:0005952 name: normal nucleosome occupancy at highly transcribed RNA polymerase II genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is normal (i.e. indistinguishable from wild type) in chromatin regions where RNA polymerase II actively transcribes genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:28218250, PomBase:mah] synonym: "normal nucleosome occupancy at highly transcribed RNA polymerase II genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleosome occupancy at highly transcribed RNA polymerase II genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000857 ! normal nucleosome positioning in euchromatin created_by: midori creation_date: 2017-03-15T16:15:39Z [Term] id: FYPO:0005953 name: increased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic G2 DNA damage checkpoint is greater than in wild type during a cellular response to ionizing radiation." [PomBase:mah] synonym: "delayed mitotic G2 DNA damage checkpoint deactivation during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "increased duration of mitotic G2 DNA damage checkpoint during cellular response to IR" EXACT [PomBase:mah] synonym: "prolonged mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0003489 ! abnormal mitotic cell cycle regulation during cellular response to ionizing radiation is_a: FYPO:0004373 ! abnormal mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2017-03-24T11:37:32Z [Term] id: FYPO:0005954 name: normal histone H2A phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured." [PomBase:mah] synonym: "normal histone H2A phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H2A phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002601 ! normal histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2017-03-24T11:41:09Z [Term] id: FYPO:0005955 name: increased duration of mitotic cell cycle def: "A cellular process phenotype in which the duration of the entire mitotic cell cycle is longer than normal." [PomBase:mah] comment: This term should only be used when the experiment does not distinguish which specific cell cycle phase is longer than normal (for example, if the time from one septation peak to the next is measured). synonym: "increased duration of mitotic cell cycle during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000059 ! abnormal mitotic cell cycle created_by: midori creation_date: 2017-03-24T11:46:56Z [Term] id: FYPO:0005956 name: abnormal protein dephosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein dephosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004426 ! abnormal protein dephosphorylation created_by: midori creation_date: 2017-03-24T13:32:07Z [Term] id: FYPO:0005957 name: decreased protein dephosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [GO:0006470, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein dephosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein dephosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005956 ! abnormal protein dephosphorylation during vegetative growth created_by: midori creation_date: 2017-03-24T13:33:38Z [Term] id: FYPO:0005958 name: decreased protein dephosphorylation during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein dephosphorylation during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein dephosphorylation during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased protein dephosphorylation during mitotic M-phase" RELATED [PomBase:vw] synonym: "decreased protein dephosphorylation during mitotic nuclear division" EXACT [GO:0140014] synonym: "decreased protein/peptide dephosphorylation during mitosis" EXACT [PomBase:mah] synonym: "reduced protein dephosphorylation during mitosis" EXACT [PomBase:mah] is_a: FYPO:0005957 ! decreased protein dephosphorylation during vegetative growth created_by: midori creation_date: 2017-03-24T13:34:53Z [Term] id: FYPO:0005959 name: multipolar spindle def: "A physical cellular phenotype in which a spindle forms with microtubules emanating from three or more poles." [PMID:15992541, PomBase:mah] is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2017-03-24T13:49:14Z [Term] id: FYPO:0005960 name: multipolar mitotic spindle def: "A physical cellular phenotype in which a mitotic spindle forms with microtubules emanating from three or more poles." [PMID:15797925, PomBase:mah] synonym: "multipolar spindle during mitosis" EXACT [PomBase:mah] synonym: "multipolar spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle is_a: FYPO:0005959 ! multipolar spindle created_by: midori creation_date: 2017-03-24T13:50:33Z [Term] id: FYPO:0005961 name: multipolar meiotic spindle def: "A physical cellular phenotype in which a meiotic spindle forms with microtubules emanating from three or more poles." [PMID:15992541, PomBase:mah] synonym: "multipolar meiotic spindles" EXACT [PomBase:mah] synonym: "multipolar spindle during meiosis" EXACT [PomBase:mah] is_a: FYPO:0000734 ! abnormal meiotic spindle is_a: FYPO:0005959 ! multipolar spindle created_by: midori creation_date: 2017-03-24T13:51:49Z [Term] id: FYPO:0005962 name: abnormal sodium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sodium ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular sodium import" EXACT [PomBase:al] synonym: "abnormal sodium import across plasma membrane" EXACT [GO:0098719] synonym: "abnormal sodium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal sodium import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sodium import into cell" EXACT [PomBase:mah] synonym: "abnormal sodium ion import" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2017-03-31T11:34:17Z [Term] id: FYPO:0005963 name: decreased sodium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sodium ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular sodium import" EXACT [PomBase:al] synonym: "decreased sodium import across plasma membrane" EXACT [GO:0098719] synonym: "decreased sodium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased sodium import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sodium import into cell" EXACT [PomBase:mah] synonym: "decreased sodium ion import" EXACT [PomBase:mah] synonym: "reduced sodium import" EXACT [PomBase:mah] is_a: FYPO:0005962 ! abnormal sodium import created_by: midori creation_date: 2017-03-31T11:34:26Z [Term] id: FYPO:0005964 name: abnormal lithium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of lithium ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular lithium import" EXACT [PomBase:al] synonym: "abnormal lithium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal lithium import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal lithium import into cell" EXACT [PomBase:mah] synonym: "abnormal lithium ion import" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2017-03-31T11:36:28Z [Term] id: FYPO:0005965 name: decreased lithium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of lithium ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular lithium import" EXACT [PomBase:al] synonym: "decreased lithium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased lithium import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lithium import into cell" EXACT [PomBase:mah] synonym: "decreased lithium ion import" EXACT [PomBase:mah] synonym: "reduced lithium import" EXACT [PomBase:mah] is_a: FYPO:0005964 ! abnormal lithium import created_by: midori creation_date: 2017-03-31T11:36:35Z [Term] id: FYPO:0005966 name: abnormal potassium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of potassium ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular potassium import" EXACT [PomBase:al] synonym: "abnormal potassium import across plasma membrane" EXACT [GO:1990573] synonym: "abnormal potassium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal potassium import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal potassium import into cell" EXACT [PomBase:mah] synonym: "abnormal potassium ion import" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2017-03-31T11:38:35Z [Term] id: FYPO:0005967 name: decreased potassium import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of potassium ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular potassium import" EXACT [PomBase:al] synonym: "decreased potassium import across plasma membrane" EXACT [GO:1990573] synonym: "decreased potassium import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased potassium import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased potassium import into cell" EXACT [PomBase:mah] synonym: "decreased potassium ion import" EXACT [PomBase:mah] synonym: "reduced potassium import" EXACT [PomBase:mah] is_a: FYPO:0005966 ! abnormal potassium import created_by: midori creation_date: 2017-03-31T11:38:41Z [Term] id: FYPO:0005968 name: resistance to sodium chloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium chloride than normal." [PomBase:mah] synonym: "resistance to NaCl" EXACT [PomBase:mah] synonym: "resistance to sodium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to sodium chloride during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to sodium chloride" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2017-03-31T11:51:37Z [Term] id: FYPO:0005969 name: resistance to magnesium chloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of magnesium chloride than normal." [PomBase:mah] synonym: "resistance to magnesium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to magnesium chloride during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to magnesium dichloride" EXACT [CHEBI:6636] synonym: "resistance to MgCl2" EXACT [PomBase:mah] synonym: "resistant to magnesium chloride" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2017-03-31T11:52:18Z [Term] id: FYPO:0005970 name: normal growth on magnesium chloride def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing magnesium chloride." [PomBase:mah] synonym: "normal cell population growth in presence of magnesium chloride" EXACT [PomBase:mah] synonym: "normal cell population growth on magnesium chloride" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on MgCl2" EXACT [PomBase:mah] synonym: "normal cellular response to magnesium chloride" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on magnesium dichloride" EXACT [CHEBI:6636] synonym: "normal vegetative cell population growth on magnesium chloride" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2017-03-31T11:54:48Z [Term] id: FYPO:0005971 name: abnormal proton transport def: "A cellular process phenotype in which proton transport is abnormal." [PomBase:mah] synonym: "abnormal H+ ion transport" EXACT [PomBase:mah] synonym: "abnormal hydrogen ion transport" EXACT [PomBase:mah] synonym: "abnormal proton transmembrane transport" EXACT [GO:1902600] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2017-03-31T12:18:20Z [Term] id: FYPO:0005972 name: decreased proton export during cellular response to glucose stimulus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of proton export is decreased during a cellular response to glucose stimulus." [PomBase:mah] synonym: "decreased H+ ion export during cellular response to glucose stimulus" RELATED [PomBase:mah] synonym: "decreased hydrogen ion export during cellular response to glucose stimulus" EXACT [PomBase:mah] synonym: "decreased proton export across plasma membrane during cellular response to glucose stimulus" EXACT [PomBase:mah] synonym: "decreased proton export during cellular response to glucose stimulus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased proton export from cell during cellular response to glucose stimulus" EXACT [PomBase:mah] synonym: "reduced proton export during cellular response to glucose stimulus" EXACT [PomBase:mah] is_a: FYPO:0005971 ! abnormal proton transport is_a: FYPO:0005973 ! abnormal transport during vegetative growth created_by: midori creation_date: 2017-03-31T12:19:20Z [Term] id: FYPO:0005973 name: abnormal transport during vegetative growth def: "A phenotype in which a specific transport process is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2017-03-31T12:20:20Z [Term] id: FYPO:0005974 name: normal mitochondrial protein level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in the mitochondria is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be measured." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal mitochondrial protein accumulation" RELATED [PomBase:mah] synonym: "normal mitochondrial protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth is_a: FYPO:0004959 ! normal level of substance in mitochondrion created_by: midori creation_date: 2017-03-31T14:07:13Z [Term] id: FYPO:0005975 name: normal lithium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lithium ion export from the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal lithium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal lithium export during vegetative growth" EXACT [PomBase:mah] synonym: "normal lithium export from cell" EXACT [PomBase:al] synonym: "normal lithium ion export from cell" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2017-03-31T14:50:24Z [Term] id: FYPO:0005976 name: increased rate of mitotic spindle elongation during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during anaphase B." [PMID:27872152, PomBase:mah] synonym: "increased rate of mitotic spindle elongation during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of mitotic spindle elongation during mitotic anaphase B" EXACT [PomBase:mah] synonym: "increased rate of mitotic spindle extension during anaphase B" EXACT [PomBase:vw] synonym: "increased rate of spindle elongation during anaphase B of mitosis" EXACT [PomBase:mah] is_a: FYPO:0007958 ! increased rate of mitotic spindle elongation created_by: midori creation_date: 2017-04-03T14:21:20Z [Term] id: FYPO:0005977 name: prion formation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a soluble protein forms prions, by refolding and assembling into highly ordered, self-propagating detergent- and protease-resistant polymers. Phenotypes associated with prions are inherited in a non-Mendelian manner." [PMID:24021964, PMID:28191457, PomBase:mah] synonym: "prion formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "prion formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2017-04-10T14:17:25Z [Term] id: FYPO:0005978 name: increased spliced cen-dg RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which spliced forms of RNAs transcribed from dg repeats in the centromere outer repeat region are present at higher levels than normal." [PMID:28231281, PomBase:mah] synonym: "increased level of spliced cen-dg RNA" EXACT [PomBase:mah] synonym: "increased level of spliced cen-dg transcripts" EXACT [PomBase:mah] synonym: "increased level of spliced centromeric dg repeat RNA" EXACT [PomBase:mah] synonym: "increased level of spliced centromeric dg repeat transcripts" EXACT [PomBase:mah] synonym: "increased spliced cen-dg RNA accumulation" RELATED [PomBase:mah] synonym: "increased spliced cen-dg RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spliced cen-dg RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased spliced cen-dg transcript level" EXACT [PomBase:mah] is_a: FYPO:0007339 ! increased cen-dg RNA level created_by: midori creation_date: 2017-04-10T14:20:45Z [Term] id: FYPO:0005979 name: abnormal actin filament bundle organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament bundle organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. Actin filament bundles are assemblies of actin filaments organized along a single axis." [GO:0061572, PomBase:mah] synonym: "abnormal actin filament bundle organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin filament bundle organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin filament bundle organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2017-04-10T14:35:37Z [Term] id: FYPO:0005980 name: decreased actin filament bundle assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles is decreased." [PMID:27075176, PomBase:mah] synonym: "actin bundling decreased" EXACT [PomBase:vw] synonym: "decreased actin bundling" EXACT [PomBase:vw] synonym: "decreased actin filament bundle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased actin filament bundle assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced filament bundle assembly" EXACT [PomBase:mah] is_a: FYPO:0006094 ! abnormal actin filament bundle assembly created_by: midori creation_date: 2017-04-10T14:35:49Z [Term] id: FYPO:0005981 name: abnormal termination of RNA polymerase I transcription def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription RNA polymerase I from a DNA template is abnormal." [GO:0006363, PomBase:mah] synonym: "abnormal RNA polymerase I transcription termination" EXACT [GO:0006363] synonym: "abnormal termination of RNA polymerase I transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal termination of RNA polymerase I transcription during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal transcription termination from Pol I promoter" EXACT [GO:0006363] synonym: "abnormal transcription termination from RNA polymerase I promoter" EXACT [GO:0006363] is_a: FYPO:0003556 ! abnormal transcription termination created_by: midori creation_date: 2017-04-13T13:41:36Z [Term] id: FYPO:0005982 name: abnormal potassium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of potassium ions out of a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular potassium export" EXACT [PomBase:al] synonym: "abnormal potassium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal potassium export during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal potassium export from cell" EXACT [PomBase:mah] synonym: "abnormal potassium ion export" EXACT [PomBase:mah] synonym: "abnormal potassium ion export across plasma membrane" EXACT [GO:0097623] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2017-04-13T13:48:18Z [Term] id: FYPO:0005983 name: decreased potassium export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of potassium ions out of a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular potassium export" EXACT [PomBase:al] synonym: "decreased potassium export during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased potassium export during vegetative growth" EXACT [PomBase:mah] synonym: "decreased potassium export from cell" EXACT [PomBase:mah] synonym: "decreased potassium ion export" EXACT [PomBase:mah] synonym: "decreased potassium ion export across plasma membrane" EXACT [GO:0097623] synonym: "reduced potassium export" EXACT [PomBase:mah] is_a: FYPO:0005982 ! abnormal potassium export created_by: midori creation_date: 2017-04-13T13:48:37Z [Term] id: FYPO:0005984 name: sensitive to Congo Red def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to the dye Congo Red. Cells stop growing (and may die) at a concentration of Congo Red that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Congo Red" EXACT [PomBase:mah] synonym: "sensitive to Congo Red during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to Congo Red during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-04-13T13:55:40Z [Term] id: FYPO:0005985 name: sensitive to acetic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acetic acid. Cells stop growing (and may die) at a concentration of acetic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to acetic acid" EXACT [PomBase:mah] synonym: "sensitive to acetic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to acetic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-04-13T13:56:32Z [Term] id: FYPO:0005986 name: linear elements present in decreased numbers def: "A physical cellular phenotype in which cells contain fewer linear elements than normal." [PomBase:mah] synonym: "decreased linear element formation" RELATED [PomBase:al] synonym: "fewer linear elements present" EXACT [PomBase:mah] synonym: "linear elements present in reduced numbers" EXACT [PomBase:mah] synonym: "reduced number of linear elements" EXACT [PomBase:vw] is_a: FYPO:0000287 ! abnormal subcellular component created_by: midori creation_date: 2017-04-13T14:10:21Z [Term] id: FYPO:0005987 name: abnormal protein localization to cell tip def: "A cell phenotype in which the localization of a protein to the cell tip is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell tip and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell tip" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell end" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2017-04-13T14:31:56Z [Term] id: FYPO:0005988 name: abolished microtubule anchoring at cell cortex of cell tip during meiotic cell cycle def: "A cell phenotype in which microtubule anchoring at the cell cortex of the cell tip does not occur during the meiotic cell cycle. Normally, anchoring maintains the localization of microtubules with their plus ends at the cell cortex." [PMID:25736293, PomBase:mah] synonym: "abolished microtubule anchoring at cell tip cortex during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abolished microtubule cortical anchoring at cell tip during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0004094 ! abnormal protein localization during meiotic cell cycle is_a: FYPO:0005987 ! abnormal protein localization to cell tip is_a: FYPO:0006393 ! localization phenotype during meiotic cell cycle created_by: midori creation_date: 2017-04-13T14:51:40Z [Term] id: FYPO:0005989 name: abnormal protein localization during mating def: "A cell phenotype that affects the localization of a protein in a cell during conjugation with cellular fusion. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abnormal cellular protein localisation during mating" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization during mating" EXACT [PomBase:mah] synonym: "abnormal protein localisation during mating" EXACT [PomBase:mah] synonym: "abnormal protein localization during conjugation with cellular fusion" EXACT [GO:0000747] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2017-04-13T15:00:29Z [Term] id: FYPO:0005990 name: abnormal maintenance of protein location in cell cortex of cell tip during karyogamy def: "A cell phenotype in which a protein is localized to the cell cortex of the cell tip during karyogamy involved in conjugation with cellular fusion, but does not remain there continuously." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal maintenance of protein localization in cell cortex of cell tip during karyogamy" EXACT [PomBase:mah] synonym: "abnormal maintenance of protein location in cell cortex of cell tip during karyogamy involved in conjugation with cellular fusion" EXACT [GO:0000742] synonym: "abnormal maintenance of protein location in cell cortex of cell tip during nuclear fusion during mating" EXACT [PomBase:mah] synonym: "unstable protein localisation to cell cortex of cell tip during karyogamy" EXACT [PomBase:mah] synonym: "unstable protein localization to cell cortex of cell tip during karyogamy" EXACT [PomBase:mah] is_a: FYPO:0005989 ! abnormal protein localization during mating created_by: midori creation_date: 2017-04-13T15:13:02Z [Term] id: FYPO:0005991 name: normal protein localization to cell cortex of cell tip during karyogamy def: "A cell phenotype in which the localization of a protein to the cell cortex of the cell tip during karyogamy involved in conjugation with cellular fusion is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell cortex of cell tip during karyogamy" EXACT [PomBase:mah] synonym: "normal protein localization to cell cortex of cell tip during karyogamy involved in conjugation with cellular fusion" EXACT [GO:0000742] synonym: "normal protein localization to cell cortex of cell tip during nuclear fusion during mating" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip cortex during karyogamy" EXACT [PomBase:mah] is_a: FYPO:0006876 ! normal protein localization to cell cortex of cell tip created_by: midori creation_date: 2017-04-13T15:18:20Z [Term] id: FYPO:0005992 name: decreased protein localization to P-bodies def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to P-bodies is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to P-bodies" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasmic P-bodies" EXACT [PomBase:vw] synonym: "decreased protein localization to P-bodies during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to P-bodies during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to P-body" EXACT [PomBase:mah] synonym: "reduced protein localization to P-bodies" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2017-04-13T15:32:32Z [Term] id: FYPO:0005993 name: normal cytoplasmic translation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translation in the cytoplasm is normal (i.e. indistinguishable from wild type). Translation is the synthesis of a protein using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain." [GO:0002181, PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by measuring incorporation of a radiolabeled amino acid. Consider annotating to 'normal protein level' (FYPO:0004083) or one of its descendants. synonym: "normal cytoplasmic protein biosynthesis" EXACT [GO:0006412, PomBase:mah] synonym: "normal cytoplasmic protein synthesis" EXACT [GO:0006412, PomBase:mah] synonym: "normal cytoplasmic translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cytoplasmic translation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000291 ! translation phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-04-13T15:56:48Z [Term] id: FYPO:0005994 name: normal mRNA deadenylation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which shortening of the poly(A) tail of a nuclear-transcribed mRNA is normal (i.e. indistinguishable from wild type)." [GO:0002183, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal deadenylation" BROAD [PomBase:vw] synonym: "normal mRNA deadenylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mRNA deadenylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear-transcribed mRNA poly(A) tail shortening" EXACT [GO:0000289, PomBase:mah] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2017-04-13T16:05:22Z [Term] id: FYPO:0005995 name: increased lncRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature long non-coding RNA (lncRNA) measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased lncRNA accumulation" RELATED [PomBase:mah] synonym: "increased lncRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased lncRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased lncRNA transcript level" BROAD [PomBase:vw] synonym: "increased long non-coding RNA level" EXACT [PomBase:mah] synonym: "increased mature lncRNA level" EXACT [PomBase:mah] is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2017-04-13T16:15:10Z [Term] id: FYPO:0005996 name: altered rRNA or precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any ribosomal RNA (rRNA) primary transcript, rRNA precursor or processing intermediate, or mature rRNA measured in a cell differs from normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal rRNA or precursor level" EXACT [PomBase:mah] synonym: "altered rRNA or precursor accumulation" RELATED [PomBase:mah] synonym: "altered rRNA or precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered rRNA or precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "altered rRNA or precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2017-04-18T16:33:05Z [Term] id: FYPO:0005997 name: altered snRNA or precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any small nuclear RNA (snRNA) primary transcript, snRNA precursor or processing intermediate, or mature snRNA measured in a cell differs from normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal snRNA or precursor level" EXACT [PomBase:mah] synonym: "altered snRNA or precursor accumulation" RELATED [PomBase:mah] synonym: "altered snRNA or precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered snRNA or precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "altered snRNA or precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2017-04-18T16:42:59Z [Term] id: FYPO:0005998 name: altered snoRNA or precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any small nucleolar RNA (snoRNA) primary transcript, snoRNA precursor or processing intermediate, or mature snoRNA measured in a cell differs from normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal snoRNA or precursor level" EXACT [PomBase:mah] synonym: "altered snoRNA or precursor accumulation" RELATED [PomBase:mah] synonym: "altered snoRNA or precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered snoRNA or precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "altered snoRNA or precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2017-04-18T16:46:19Z [Term] id: FYPO:0005999 name: altered tRNA or precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any transfer RNA (tRNA) primary transcript, tRNA precursor or processing intermediate, or mature tRNA measured in a cell differs from normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal tRNA or precursor level" EXACT [PomBase:mah] synonym: "altered tRNA or precursor accumulation" RELATED [PomBase:mah] synonym: "altered tRNA or precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered tRNA or precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "altered tRNA or precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2017-04-18T16:47:49Z [Term] id: FYPO:0006000 name: normal rRNA or precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any ribosomal RNA (rRNA) primary transcript, rRNA precursor or processing intermediate, or mature rRNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal rRNA or precursor accumulation" RELATED [PomBase:mah] synonym: "normal rRNA or precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rRNA or precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "normal rRNA or precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2017-04-18T16:48:59Z [Term] id: FYPO:0006001 name: abolished protein localization to P-bodies def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to P-bodies does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to P-bodies" EXACT [PomBase:mah] synonym: "abolished protein localization to cytoplasmic P-bodies" EXACT [PomBase:vw] synonym: "abolished protein localization to P-bodies during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to P-bodies during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to P-body" EXACT [PomBase:mah] synonym: "protein localization to P-bodies abolished" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2017-04-18T17:03:07Z [Term] id: FYPO:0006002 name: normal protein localization to P-bodies def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to P-bodies is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to P-bodies" EXACT [PomBase:mah] synonym: "normal protein localization to cytoplasmic P-bodies" EXACT [PomBase:vw] synonym: "normal protein localization to P-bodies during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to P-bodies during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to P-body" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-04-18T17:03:11Z [Term] id: FYPO:0006003 name: normal cellular component organization def: "A cellular process phenotype in which any process of cellular component organization at the cellular level is normal (i.e. indistinguishable from wild type)." [GO:0016043, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal cellular component organisation" EXACT [PomBase:mah] synonym: "normal cellular component organization at cellular level" EXACT [PomBase:mah] is_a: FYPO:0000334 ! cellular component organization phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2017-04-24T13:58:39Z [Term] id: FYPO:0006004 name: normal interphase microtubule organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule organization is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [GO:0031122, PomBase:mah] synonym: "normal cytoplasmic microtubule organization during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule organization during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule organization during mitotic interphase" EXACT [PomBase:mah] synonym: "normal interphase cytoplasmic microtubule organization" EXACT [PomBase:mah] synonym: "normal interphase microtubule organisation" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-04-24T14:14:55Z [Term] id: FYPO:0006005 name: normal actomyosin contractile ring localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring localization is normal (i.e. indistinguishable from wild type). Actomyosin contractile ring localization is the part of cytokinesis in which the actomyosin contractile ring is assembled and/or maintained in a specific location." [GO:1902405, PomBase:mah] synonym: "normal actomyosin contractile ring localisation" EXACT [PomBase:mah] synonym: "normal actomyosin contractile ring localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal actomyosin contractile ring positioning" EXACT [Pombase:vw] synonym: "normal cytokinetic contractile ring localization" EXACT [PomBase:vw] synonym: "normal mitotic actomyosin contractile ring localization" EXACT [GO:1902405, PomBase:mah] synonym: "normal mitotic contractile ring localization" EXACT [PomBase:vw] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0007827 ! normal actomyosin contractile ring organization created_by: midori creation_date: 2017-04-24T14:27:31Z [Term] id: FYPO:0006006 name: inviable binucleate aseptate cell with cell cycle arrest in mitotic telophase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested in telophase. The post-anaphase microtubule array is present." [PMID:12791993, PomBase:mah] synonym: "inviable binucleate aseptate cell with arrest in telophase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable binucleate aseptate cell with cell cycle arrest in mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "inviable binucleate aseptate cell with mitotic cell cycle arrest in telophase" EXACT [PomBase:mah] synonym: "lethal; binucleate aseptate cell with cell cycle arrest in mitotic telophase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in telophase with inviable binucleate aseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000622 ! abnormal cell cycle arrest in mitotic telophase is_a: FYPO:0005689 ! inviable binucleate aseptate cell with mitotic cell cycle arrest before cell separation relationship: has_part FYPO:0000622 ! abnormal cell cycle arrest in mitotic telophase created_by: midori creation_date: 2017-04-24T14:34:26Z [Term] id: FYPO:0006007 name: normal duration of protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the site of cell division is normal (i.e. indistinguishable from wild type)." [PMID:26941334, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal duration of protein localisation to cell division site" EXACT [PomBase:mah] synonym: "normal duration of protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal duration of protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "normal duration of protein recruitment to cell division site" RELATED [PomBase:vw] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-04-24T14:49:59Z [Term] id: FYPO:0006008 name: normal onset of protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PMID:26941334, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal onset of protein localisation to cell division site" EXACT [PomBase:mah] synonym: "normal onset of protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal onset of protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "normal onset of protein recruitment to cell division site" RELATED [PomBase:vw] synonym: "normal timing of protein localization to cell division site" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-04-24T14:51:03Z [Term] id: FYPO:0006009 name: actin cables present in decreased numbers during cytokinesis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cables than normal during cytokinesis." [PMID:26941334, PomBase:mah] synonym: "actin cables present in decreased numbers during cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cables present in decreased numbers during cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "actin cables present in reduced numbers during cytokinesis" EXACT [PomBase:mah] synonym: "decreased level of actin cables during cytokinesis" RELATED [PomBase:al] synonym: "fewer actin cables present during cytokinesis" EXACT [PomBase:mah] synonym: "formin-nucleated actin cables present in decreased numbers during cytokinesis" EXACT [GO:0070648, PomBase:mah] is_a: FYPO:0006215 ! actin cables present in decreased numbers created_by: midori creation_date: 2017-04-24T14:55:37Z [Term] id: FYPO:0006010 name: abolished shmoo contact with partner cell def: "A cellular process phenotype in which a mating projection is assembled but does not meet a cell of the opposite mating type." [PMID:28410370, PomBase:mah] comment: The difference between this term and FYPO:0001873 is that the former describes failure to make contact with available cells of the opposite mating type, whereas the latter describes shmoo formation when no compatible cells are present. synonym: "abolished shmoo contact with partner cell during conjugation" EXACT [PomBase:mah] synonym: "shmoo does not meet partner cell" EXACT [PomBase:mah] synonym: "shmoo without partner cell" BROAD [PMID:28410370] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2017-04-26T15:12:54Z [Term] id: FYPO:0006011 name: shmoo formation at cell side def: "A cellular process phenotype in which mating projection assembly occurs along the lateral portion of the long axis of the cell instead of at one cell end." [PMID:28410370, PomBase:mah] synonym: "lateral shmoo formation" EXACT [PomBase:mah] synonym: "mating projection assembly at cell side" EXACT [PomBase:mah] synonym: "shmoo formation on cell side" EXACT [PomBase:mah] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2017-04-26T15:31:07Z [Term] id: FYPO:0006012 name: elongated cell with abolished shmoo formation def: "A cell morphology phenotype in which a cell is elongated, and does not form a mating projection under conditions that normally induce shmooing." [PMID:28410370, PomBase:mah] synonym: "elongated cell with abolished shmoo formation during nitrogen starvation" EXACT [PomBase:mah] synonym: "elongated non-mated cell" RELATED [PomBase:mah] synonym: "large non-mated cells" RELATED [PMID:28410370] is_a: FYPO:0000569 ! abolished shmoo formation is_a: FYPO:0000998 ! elongated cell during nitrogen starvation created_by: midori creation_date: 2017-04-26T15:35:29Z [Term] id: FYPO:0006013 name: large ascus def: "A phenotype in which the ascus is larger than normal." [PMID:28410370, PomBase:mah] synonym: "enlarged ascus" EXACT [PomBase:mah] synonym: "increased ascus size" EXACT [PomBase:mah] synonym: "large asci" EXACT [PomBase:mah] is_a: FYPO:0005156 ! abnormal ascus morphology created_by: midori creation_date: 2017-04-26T15:37:44Z [Term] id: FYPO:0006014 name: promiscuous mating def: "A cellular process phenotype in which one cell forms multiple mating projections that engage multiple partner cells." [PMID:28410370, PomBase:mah] synonym: "conjugation with multiple partner cells" EXACT [PomBase:mah] synonym: "formation of multiple mating projections" RELATED [PomBase:mah] synonym: "formation of multiple shmoos" RELATED [PomBase:mah] synonym: "mating with multiple partner cells" EXACT [PomBase:mah] synonym: "promiscuous conjugation" EXACT [PomBase:mah] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2017-04-26T15:40:21Z [Term] id: FYPO:0006015 name: multiseptate cell with shmoo def: "A cell phenotype in which a cell has more than one septum, and forms a mating projection." [PMID:28410370, PomBase:mah] synonym: "large non-mated cells" RELATED [PMID:28410370] synonym: "multiseptate shmooing cell" EXACT [PomBase:mah] is_a: FYPO:0004295 ! multiseptate cell created_by: midori creation_date: 2017-04-28T12:13:25Z [Term] id: FYPO:0006016 name: sensitive to urea def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to urea. Cells stop growing (and may die) at a concentration of urea that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to urea" EXACT [PomBase:mah] synonym: "sensitive to urea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to urea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-05-03T15:56:01Z [Term] id: FYPO:0006017 name: normal growth on urea def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing urea." [PomBase:mah] synonym: "normal cell population growth in presence of urea" EXACT [PomBase:mah] synonym: "normal cell population growth on urea" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on urea" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2017-05-03T15:58:00Z [Term] id: FYPO:0006018 name: decreased nuclear pore density def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer nuclear pore complexes than normal." [PMID:28242692, PomBase:mah] synonym: "decreased NPC density" EXACT [PomBase:mah] synonym: "decreased nuclear pore complex density" EXACT [PomBase:mah] synonym: "decreased nuclear pore density during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased nuclear pore density during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear pore complexes present in decreased number" EXACT [GO:0005643] synonym: "nuclear pores present in decreased number" EXACT [PomBase:mah] synonym: "reduced nuclear pore density" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2017-05-03T16:11:02Z [Term] id: FYPO:0006019 name: karmellae present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which excess endoplasmic reticulum (ER) membrane forms stacks adjacent to the nucleus, known as karmellae." [PMID:16607018, PMID:28242692, PomBase:mah] synonym: "karmellae formation" RELATED [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth is_a: FYPO:0001784 ! excess endoplasmic reticulum membrane present created_by: midori creation_date: 2017-05-05T12:06:55Z [Term] id: FYPO:0006020 name: abnormal protein distribution along RNA polymerase II-transcribed genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is abnormal." [PMID:28366642, PomBase:mah] comment: Usually assayed for RNA polymerase, transcription factors, or other components of the transcription machinery. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein distribution across RNA polymerase II-transcribed genes" EXACT [PMID:28366642] synonym: "abnormal protein distribution along RNA polymerase II-regulated genes" EXACT [PomBase:mah] synonym: "abnormal protein distribution along RNA polymerase II-transcribed genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein distribution along RNA polymerase II-transcribed genes during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein distribution in chromatin along RNA polymerase II-transcribed genes" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromatin along RNA polymerase II-transcribed genes" EXACT [PomBase:mah] is_a: FYPO:0007465 ! altered spatial extent of protein localization to chromatin created_by: midori creation_date: 2017-05-08T15:28:06Z [Term] id: FYPO:0006021 name: normal protein distribution along RNA polymerase II-transcribed genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type)." [PMID:28366642, PomBase:mah] comment: Usually assayed for RNA polymerase, transcription factors, or other components of the transcription machinery. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein distribution across RNA polymerase II-transcribed genes" EXACT [PMID:28366642] synonym: "normal protein distribution along RNA polymerase II-regulated genes" EXACT [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-transcribed genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-transcribed genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein distribution in chromatin along RNA polymerase II-transcribed genes" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin along RNA polymerase II-transcribed genes" EXACT [PomBase:mah] is_a: FYPO:0007536 ! normal protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth created_by: midori creation_date: 2017-05-08T15:32:57Z [Term] id: FYPO:0006022 name: abnormal spindle pole body morphology during meiosis I def: "A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal during the first meiotic nuclear division." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "abnormal SPB morphology during meiosis I" EXACT [PomBase:mah] synonym: "abnormal spindle pole body morphology during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal spindle pole body structure during meiosis I" NARROW [PomBase:mah] is_a: FYPO:0006406 ! abnormal spindle pole body morphology during meiotic cell cycle relationship: output_of FYPO:0003561 ! abnormal prospore-specific spindle pole body remodeling created_by: midori creation_date: 2017-05-08T15:38:36Z [Term] id: FYPO:0006023 name: elongated multinucleate multiseptate vegetative cell, irregular septum position def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, has two or more nuclei and more than one septum, and the septa are neither grouped together nor all placed with each septum forming a compartment with a single nucleus. Septa may be present singly or in pairs, and in any location relative to the nuclei." [PMID:11294907, PomBase:mah] synonym: "elongated multinucleate multiseptate vegetative cell, irregular septum position during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated multinucleate multiseptate vegetative cell, irregular septum position during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell created_by: midori creation_date: 2017-05-12T11:46:53Z [Term] id: FYPO:0006024 name: normal actin filament binding def: "A molecular function phenotype in which the binding of a protein to one or more actin filaments is normal (i.e. indistinguishable from wild type). The relevant actin-binding protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal F-actin binding" EXACT [PomBase:mah] synonym: "normal filamentous actin binding" EXACT [PomBase:mah] is_a: FYPO:0000703 ! normal protein-protein interaction created_by: midori creation_date: 2017-05-12T12:13:19Z [Term] id: FYPO:0006025 name: abolished actin filament binding def: "A molecular function phenotype in which the binding of a protein to one or more actin filaments does not occur. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished F-actin binding" EXACT [PomBase:mah] synonym: "abolished filamentous actin binding" EXACT [PomBase:mah] synonym: "actin filament binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction created_by: midori creation_date: 2017-05-12T12:15:35Z [Term] id: FYPO:0006026 name: abolished actin filament bundle assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles does not occur." [PMID:11694585, PomBase:mah] synonym: "abolished actin bundling" EXACT [PomBase:vw] synonym: "abolished actin filament bundle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished actin filament bundle assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished actin filament bundle formation" EXACT [PomBase:mah] synonym: "actin bundling abolished" EXACT [PomBase:vw] is_a: FYPO:0006094 ! abnormal actin filament bundle assembly created_by: midori creation_date: 2017-05-12T13:44:01Z [Term] id: FYPO:0006027 name: actin cables present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cables than normal." [PMID:11694585, PomBase:mah] synonym: "actin cables present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cables present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "extra actin cables present" EXACT [PomBase:mah] synonym: "formin-nucleated actin cables present in increased numbers" EXACT [GO:0070648, PomBase:mah] synonym: "increased level of actin cables" RELATED [PomBase:al] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2017-05-12T13:51:19Z [Term] id: FYPO:0006028 name: decreased protein localization to actin cortical patch, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is decreased, and some of the protein is present in the cytoplasm instead." [PMID:11694585, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actin cortical patch, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actin cortical patch, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to actin cortical patch, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actin patch, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "reduced protein localization to actin cortical patch, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0006120 ! decreased protein localization to actin cortical patch relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2017-05-12T14:03:04Z [Term] id: FYPO:0006029 name: decreased actin filament depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament depolymerization, i.e. the removal of actin monomers from a filament, occurs to a lower extent than normal." [PMID:11694585, PomBase:mah] synonym: "decreased actin filament depolymerisation" EXACT [PomBase:mah] synonym: "decreased actin filament depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased actin filament depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced actin filament depolymerization" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth created_by: midori creation_date: 2017-05-12T14:08:24Z [Term] id: FYPO:0006030 name: actin cortical patches absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable actin cortical patches." [PomBase:mah] synonym: "absent actin cortical patches" EXACT [PomBase:mah] synonym: "actin cortical patches absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cortical patches absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "actin patches absent from cell" EXACT [PomBase:mah] is_a: FYPO:0004964 ! actin cortical patches present in decreased numbers created_by: midori creation_date: 2017-05-12T14:14:09Z [Term] id: FYPO:0006031 name: delayed onset of mitotic DNA replication initiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins later than normal." [PMID:28481910, PomBase:mah] synonym: "delayed mitotic DNA replication initiation" EXACT [PomBase:mah] synonym: "delayed onset of DNA replication initiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "delayed onset of DNA replication initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001344 ! abnormal mitotic DNA replication initiation created_by: midori creation_date: 2017-05-15T15:48:52Z [Term] id: FYPO:0006032 name: decreased protein localization to chromatin during mitotic DNA replication def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during mitotic DNA replication." [PMID:28481910, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin during mitotic DNA replication" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin during DNA replication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin during DNA replication during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin during mitotic DNA replication" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2017-05-15T15:51:03Z [Term] id: FYPO:0006033 name: normal protein localization to chromatin during mitotic DNA replication def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during mitotic DNA replication." [PMID:28481910, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin during mitotic DNA replication" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during DNA replication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin during DNA replication during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2017-05-15T15:53:29Z [Term] id: FYPO:0006034 name: normal mitochondrion def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, morphology, or other physical characteristic of the mitochondrion is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitochondria" EXACT [PomBase:mah] synonym: "normal mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2017-06-05T16:22:28Z [Term] id: FYPO:0006035 name: normal mitochondrial membrane potential def: "A physical cellular phenotype in which the mitochondrial membrane potential, i.e. the electric potential existing across the mitochondrial membrane, is normal (i.e. indistinguishable from wild type)." [GO:0051881, PMID:14767070, PomBase:mah] synonym: "normal mitochondrial membrane polarization" EXACT [PomBase:mah] synonym: "normal mitochondrial membrane potential during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial membrane potential during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006034 ! normal mitochondrion created_by: midori creation_date: 2017-06-05T16:22:48Z [Term] id: FYPO:0006036 name: increased cytosolic monomeric ribosome level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more monomeric ribosomes (80S monosomes) in the cytosol than normal." [PMID:10462529, PomBase:mah] synonym: "cytosolic monomeric ribosomes present at increased level" EXACT [PomBase:mah] synonym: "increased cytosolic 80S monosome level" EXACT [PomBase:mah] synonym: "increased cytosolic monomeric 80S ribosome level" EXACT [PomBase:mah] synonym: "increased cytosolic monomeric ribosome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cytosolic monomeric ribosome level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cytosolic ribosome level" BROAD [PomBase:mah] synonym: "increased level of cytosolic monomeric ribosomes" EXACT [PomBase:al] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2017-06-05T16:26:56Z [Term] id: FYPO:0006037 name: decreased cytosolic half-mer polysome level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer half-mer polysomes in the cytosol than normal. A half-mer polysome is a complex consisting of an mRNA bound to a single small ribosomal subunit, followed by one or more complete bound ribosomes." [PMID:10462529, PMID:18611858, PMID:19806183, PMID:26122634, PomBase:mah] synonym: "cytosolic half-mer polysomes present at decreased level" EXACT [PomBase:mah] synonym: "decreased cytosolic half-mer polysome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytosolic half-mer polysome level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cytosolic halfmer polysome level" EXACT [PomBase:mah] synonym: "decreased level of cytosolic half-mer polysomes" RELATED [PomBase:al] synonym: "reduced cytosolic half-mer polysome level" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: midori creation_date: 2017-06-05T16:28:21Z [Term] id: FYPO:0006038 name: normal cytoplasmic translational initiation def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which the initiation of translation in the cytoplasm is normal (i.e. indistinguishable from wild type). Translational initiation is he process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm." [GO:0002183, PomBase:mah] synonym: "normal cytoplasmic translation initiation" EXACT [PomBase:vw] synonym: "normal cytoplasmic translational initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cytoplasmic translational initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000291 ! translation phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-06-05T16:29:49Z [Term] id: FYPO:0006039 name: incomplete mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic metaphase chromosome recapture does not proceed until the kinetochore has moved all the way to the spindle pole body (SPB), but kinetochores instead pause abnormally near the SPB." [PMID:27146110, PomBase:mah] synonym: "incomplete chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "incomplete chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "incomplete kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "incomplete metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "incomplete mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "incomplete mitotic metaphase kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "incomplete sister kinetochore recapture" EXACT [GO:1990942] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2017-06-07T11:24:42Z [Term] id: FYPO:0006040 name: abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubules attached to the kinetochore lengthen instead of shortening during mitotic metaphase chromosome recapture." [PMID:27146110, PomBase:mah] synonym: "abnormal kinetochore microtubule polymerization during chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "abnormal kinetochore microtubule polymerization during chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "abnormal kinetochore microtubule polymerization during kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "abnormal kinetochore microtubule polymerization during metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal kinetochore microtubule polymerization during mitotic metaphase kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "abnormal kinetochore microtubule polymerization during sister kinetochore recapture" EXACT [GO:1990942] is_a: FYPO:0004614 ! abnormal microtubule polymerization during vegetative growth is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2017-06-07T11:32:18Z [Term] id: FYPO:0006041 name: decreased rate of mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic metaphase chromosome recapture is decreased." [PMID:27146110, PomBase:mah] synonym: "decreased rate of chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "decreased rate of chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "decreased rate of kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "decreased rate of metaphase chromosome recapture during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of mitotic kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "decreased rate of mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of mitotic metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "decreased rate of mitotic sister kinetochore recapture" EXACT [GO:1990942] synonym: "increased time to mitotic metaphase chromosome recapture" RELATED [PMID:27146110] synonym: "reduced rate of mitotic metaphase chromosome recapture" EXACT [PomBase:mah] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2017-06-07T11:34:31Z [Term] id: FYPO:0006042 name: increased rate of mitotic metaphase chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic metaphase chromosome recapture is increased." [PMID:27146110, PomBase:mah] synonym: "decreased time to mitotic metaphase chromosome recapture" RELATED [PMID:27146110] synonym: "increased rate of chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "increased rate of chromosome recapture during mitotic metaphase" EXACT [PomBase:mah] synonym: "increased rate of kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "increased rate of metaphase chromosome recapture during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of mitotic kinetochore retrieval" EXACT [GO:1990942, PomBase:mah] synonym: "increased rate of mitotic metaphase chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of mitotic metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "increased rate of mitotic sister kinetochore recapture" EXACT [GO:1990942] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2017-06-07T11:37:06Z [Term] id: FYPO:0006043 name: increased rate of kinetochore sliding during chromosome recapture def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of kinetochore sliding, i.e. the movement of a kinetochore along spindle microtubules, during mitotic chromosome recapture is increased." [PMID:27146110, PomBase:mah] comment: Note that, although the movement affected in this phenotype is often described as "kinetochore migration" or "kinetochore sliding", the entire chromosome moves along the spindle microtubules. synonym: "increased rate of chromosome migration during chromosome recapture" EXACT [PomBase:vw] synonym: "increased rate of chromosome movement during chromosome recapture" EXACT [PomBase:vw] synonym: "increased rate of kinetochore migration during chromosome recapture" EXACT [PomBase:vw] synonym: "increased rate of kinetochore sliding along kinetochore microtubule towards spindle pole body during chromosome recapture" EXACT [PomBase:vw] synonym: "increased rate of kinetochore sliding during chromosome recapture during mitosis" EXACT [PomBase:mah] synonym: "increased rate of kinetochore sliding during chromosome recapture during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of kinetochore sliding during kinetochore retrieval" EXACT [GO:1990942] synonym: "increased rate of kinetochore sliding during kinetochore retrieval in mitotic metaphase" EXACT [PomBase:vw] synonym: "increased rate of kinetochore sliding during metaphase chromosome retrieval to the spindle pole body" EXACT [GO:1990942] synonym: "increased rate of kinetochore sliding during mitotic metaphase chromosome recapture" EXACT [PomBase:vw] synonym: "increased rate of kinetochore sliding during sister kinetochore recapture" EXACT [GO:1990942] synonym: "increased rate of kinetochore sliding towards SPB during chromosome recapture" EXACT [PomBase:vw] synonym: "increased rate of kinetochore sliding towards spindle pole body during chromosome recapture" EXACT [PomBase:vw] is_a: FYPO:0005362 ! abnormal mitotic metaphase chromosome recapture created_by: midori creation_date: 2017-06-07T11:38:20Z [Term] id: FYPO:0006044 name: long mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form mitotic spindle microtubules that are longer than normal, and the protruding kinetochore microtubules are surrounded by an extension of the nuclear envelope, with the kinetochore-attached end at the distal tip of the protrusion." [PMID:27146110, PomBase:mah] synonym: "elongated mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion" EXACT [PomBase:mah] synonym: "elongated mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion during M-phase" EXACT [PomBase:vw] synonym: "long mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope deformation" RELATED [PomBase:vw] synonym: "long mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion during vegetative growth" EXACT [PomBase:mah] synonym: "long mitotic spindle microtubules with nuclear envelope protrusion from the kinetochore attached end of the microtubule" EXACT [PomBase:vw] synonym: "nuclear envelope protrusion with long mitotic kinetochore microtubules and kinetochore at tip of nuclear envelope protrusion" EXACT [PomBase:vw] is_a: FYPO:0000055 ! long microtubules is_a: FYPO:0000733 ! long mitotic spindle is_a: FYPO:0003788 ! nuclear envelope protrusion present during mitosis relationship: has_part FYPO:0003788 ! nuclear envelope protrusion present during mitosis created_by: midori creation_date: 2017-06-07T11:40:19Z [Term] id: FYPO:0006045 name: delayed onset of mitotic sister chromatid biorientation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid biorientation begins later than normal." [PMID:27146110, PomBase:mah] synonym: "delayed mitotic sister chromatid biorientation" EXACT [PomBase:mah] synonym: "delayed onset of mitotic sister chromatid biorientation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of sister chromatid biorientation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic sister chromatid biorientation delayed" EXACT [PomBase:vw] is_a: FYPO:0000326 ! abnormal mitotic sister chromatid biorientation created_by: midori creation_date: 2017-06-07T11:51:34Z [Term] id: FYPO:0006046 name: uncentered mitotic chromosome congression def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which in which chromosomes do not align at the midpoint of the long axis of the mitotic spindle during metaphase chromosome congression." [PMID:27146110, PomBase:mah] synonym: "abnormal mitotic chromosome congression with loss of chromosome centering" EXACT [PomBase:vw] synonym: "loss of mitotic chromosome centering" EXACT [PMID:27146110] synonym: "uncentered chromosome congression during mitosis" EXACT [PomBase:mah] synonym: "uncentered chromosome congression during mitotic metaphase" EXACT [PomBase:mah] synonym: "uncentered mitotic chromosome congression during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000030 ! abnormal mitotic chromosome congression created_by: midori creation_date: 2017-06-07T11:54:57Z [Term] id: FYPO:0006047 name: decreased interkinetochore distance before mitotic anaphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between sister kinetochores is smaller than normal before the onset of mitotic anaphase." [PMID:27146110, PomBase:mah] comment: Use this term in cases where "stretching" refers to the distance between sister kinetochores of duplicated chromosomes that are bioriented on the spindle during mitosis. Also see 'abnormal kinetochore localization' (FYPO:0001778) and 'abnormal mitotic sister chromatid segregation' (FYPO:0000141). synonym: "decreased distance between mitotic kinetochores" RELATED [PomBase:vw] synonym: "decreased interkinetochore distance before anaphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased interkinetochore distance before anaphase onset" EXACT [PomBase:mah] synonym: "decreased interkinetochore distance before mitotic anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased kinetochore stretching before mitotic anaphase" RELATED [PomBase:mah] synonym: "decreased sister kinetochore distance before mitotic anaphase" EXACT [PomBase:mah] synonym: "reduced interkinetochore distance before mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0001778 ! abnormal centromere localization created_by: midori creation_date: 2017-06-07T11:57:57Z [Term] id: FYPO:0006048 name: unstable mitotic spindle def: "A cell phenotype in which a mitotic spindle assembles, but does not remain at a constant length or gradually elongate." [PMID:23885124, PMID:27146110, PomBase:mah] synonym: "unstable mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "unstable mitotic spindle length" EXACT [PMID:23885124, PMID:27146110] synonym: "unstable spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation created_by: midori creation_date: 2017-06-07T11:59:45Z [Term] id: FYPO:0006049 name: fluctuating mitotic spindle length def: "A cell phenotype in which a mitotic spindle assembles, but then undergoes large changes in length, instead of remaining at a constant length or gradually elongating." [PMID:27146110, PomBase:mah] synonym: "fluctuating mitotic spindle length during vegetative growth" EXACT [PomBase:mah] synonym: "fluctuating spindle length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0006048 ! unstable mitotic spindle created_by: midori creation_date: 2017-06-07T12:01:47Z [Term] id: FYPO:0006050 name: normal rate of mitotic sister chromatid separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [PMID:27146110, PomBase:mah] synonym: "normal mitotic sister chromatid separation rate" EXACT [PomBase:mah] synonym: "normal rate of mitotic sister chromatid separation during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of sister chromatid separation during mitosis" EXACT [PomBase:mah] synonym: "normal rate of sister chromatid separation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004301 ! normal mitotic sister chromatid separation created_by: midori creation_date: 2017-06-07T12:14:38Z [Term] id: FYPO:0006051 name: decreased lipid droplet localization to prospore membrane leading edge def: "A cellular process phenotype in which the localization of lipid droplets to the prospore membrane occurs to a lower extent than normal." [PMID:28011631, PomBase:mah] synonym: "decreased lipid droplet localization to forespore membrane leading edge" EXACT [PomBase:mah] synonym: "decreased lipid droplet localization to FSM leading edge" EXACT [PomBase:vw] synonym: "decreased lipid particle localization to prospore membrane leading edge" EXACT [PomBase:mah] synonym: "reduced lipid droplet localization to prospore membrane leading edge" EXACT [PomBase:mah] is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2017-06-07T13:02:13Z [Term] id: FYPO:0006052 name: normal lipid droplet localization to prospore membrane leading edge def: "A cellular process phenotype in which the localization of lipid droplets to the prospore membrane occurs to a normal (i.e. indistinguishable from wild type) extent." [PMID:28011631, PomBase:mah] synonym: "normal lipid droplet localization to forespore membrane leading edge" EXACT [PomBase:mah] synonym: "normal lipid droplet localization to FSM leading edge" EXACT [PomBase:vw] synonym: "normal lipid particle localization to prospore membrane leading edge" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2017-06-07T13:06:33Z [Term] id: FYPO:0006053 name: lipid droplets present in spore cytoplasm in decreased numbers, mislocalized to ascus epiplasm def: "A physical cellular phenotype in which the spore cytoplasm contains fewer lipid droplets than normal. Some lipid droplets are present in the ascus epiplasm instead." [PomBase:mah] synonym: "decreased lipid droplet level in spore cytoplasm, with droplets mislocalized to ascus epiplasm" EXACT [PomBase:mah] synonym: "lipid droplets present in spore cytoplasm in reduced numbers, mislocalized to ascus epiplasm" EXACT [PomBase:mah] synonym: "reduced inclusion of lipid droplets in spore cytoplasm, mislocalized to ascus cytoplasm" EXACT [PomBase:vw] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2017-06-07T13:10:42Z [Term] id: FYPO:0006054 name: decreased lipid droplet formation def: "A cellular process phenotype in which the occurrence of lipid droplet formation is decreased." [PomBase:mah] synonym: "decreased lipid droplet assembly" EXACT [PomBase:mah] synonym: "decreased lipid particle formation" EXACT [PomBase:mah] synonym: "reduced lipid droplet formation" EXACT [PomBase:mah] is_a: FYPO:0008430 ! abnormal lipid droplet formation relationship: has_output FYPO:0002552 ! lipid droplets present in decreased numbers created_by: midori creation_date: 2017-06-07T13:22:18Z [Term] id: FYPO:0006055 name: normal protein localization to meiotic spindle pole body during meiosis II def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is normal (i.e. indistinguishable from wild type) during the second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to meiotic spindle pole body during meiosis II" EXACT [PomBase:mah] synonym: "normal protein localization to meiotic SPB during meiosis II" EXACT [PomBase:mah] synonym: "normal protein localization to meiotic spindle pole body during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003541 ! normal protein localization to meiotic spindle pole body created_by: midori creation_date: 2017-06-07T13:46:41Z [Term] id: FYPO:0006056 name: prospore formation with spindle pole body dissociated from prospore membrane def: "A cellular process phenotype in which the spindle pole body does not attach to the prospore membrane during prospore membrane formation and closure. Normally, the prospore membrane associates with the spindle pole body from late anaphase of meiosis II until the membrane has completely closed." [PMID:18411246, PomBase:mah] synonym: "forespore formation with spindle pole body dissociated from forespore membrane" EXACT [PomBase:mah] synonym: "forespore formation with spindle pole body dissociated from FSM" EXACT [PomBase:mah] synonym: "prospore formation with SPB dissociated from prospore membrane" EXACT [PomBase:mah] synonym: "spindle pole body separated from the FSM" EXACT [PomBase:vw] is_a: FYPO:0000196 ! abnormal prospore formation created_by: midori creation_date: 2017-06-07T14:25:03Z [Term] id: FYPO:0006057 name: abnormal vacuole fusion def: "A cellular process phenotype in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is abnormal." [GO:0042144, PomBase:mah] synonym: "abnormal homotypic vacuole fusion" EXACT [GO:0042144] synonym: "abnormal vacuole fusion, non-autophagic" EXACT [GO:0042144] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2017-06-07T14:34:26Z [Term] id: FYPO:0006058 name: abnormal vacuole fusion during sporulation def: "A cellular process phenotype in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is abnormal during sporulation." [GO:0042144, PomBase:mah] synonym: "abnormal homotypic vacuole fusion during sporulation" EXACT [GO:0042144] synonym: "abnormal vacuole fusion, non-autophagic, during sporulation" EXACT [GO:0042144] is_a: FYPO:0006057 ! abnormal vacuole fusion created_by: midori creation_date: 2017-06-07T14:36:25Z [Term] id: FYPO:0006059 name: abnormal protein localization to septin ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to septin ring" EXACT [PomBase:mah] synonym: "abnormal protein localization to septin ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to septin ring during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2017-06-07T15:30:14Z [Term] id: FYPO:0006060 name: abolished protein localization to septin ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to septin ring" EXACT [PomBase:mah] synonym: "abolished protein localization to septin ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from septin ring" RELATED [PomBase:mah] synonym: "protein localization to septin ring abolished" EXACT [PomBase:mah] synonym: "protein localization to septin ring abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0006059 ! abnormal protein localization to septin ring created_by: midori creation_date: 2017-06-07T15:32:08Z [Term] id: FYPO:0006061 name: abnormal septin ring assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring assembly is abnormal." [PomBase:mah] synonym: "abnormal septin ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septin ring formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2017-06-07T15:34:51Z [Term] id: FYPO:0006062 name: ectopic septin ring assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which one septin ring assembles in the normal location, but one or more additional septin rings also form in abnormal locations." [PMID:15385632, PomBase:mah] synonym: "ectopic septin ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "ectopic septin ring formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006061 ! abnormal septin ring assembly during vegetative growth created_by: midori creation_date: 2017-06-07T15:36:43Z [Term] id: FYPO:0006063 name: septin ring assembly during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring assembly begins in mitotic interphase instead of during nuclear division." [PMID:15385632, PomBase:mah] synonym: "septin ring assembly during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "septin ring assembly during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "septin ring formation during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0006061 ! abnormal septin ring assembly during vegetative growth created_by: midori creation_date: 2017-06-07T15:38:49Z [Term] id: FYPO:0006064 name: abnormal septin ring disassembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring disassembly is abnormal." [PMID:15385632, PomBase:mah] synonym: "abnormal septin ring disassembly during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2017-06-07T15:42:04Z [Term] id: FYPO:0006065 name: delayed onset of septin ring disassembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring disassembly begins later than normal." [PMID:15385632, PomBase:mah] synonym: "delayed onset of septin ring disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed septin ring disassembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006064 ! abnormal septin ring disassembly during vegetative growth created_by: midori creation_date: 2017-06-07T15:42:11Z [Term] id: FYPO:0006066 name: abolished tubulin heterodimer binding def: "A molecular function phenotype in which the binding of a protein to one or more alpha/beta tubulin heterodimers does not occur. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with tubulin dimers that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished protein-protein interaction with tubulin dimer" EXACT [PomBase:mah] synonym: "abolished protein-protein interaction with tubulin heterodimer" EXACT [PomBase:mah] synonym: "abolished tubulin dimer binding" EXACT [PomBase:mah] synonym: "tubulin heterodimer binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction created_by: midori creation_date: 2017-06-07T15:49:23Z [Term] id: FYPO:0006067 name: abolished microtubule polymerization def: "A cell phenotype in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, does not occur." [PMID:22696680, PomBase:mah] synonym: "abolished microtubule catastrophe" RELATED [PomBase:mah] synonym: "abolished microtubule polymerisation" EXACT [PomBase:mah] synonym: "abolished microtubule polymerization" RELATED [PomBase:mah] synonym: "abolished microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished microtubule polymerization during vegetative growth" EXACT [PomBase:mah] synonym: "abolished microtubule shrinkage" RELATED [PomBase:vw] synonym: "microtubule polymerization abolished" EXACT [PomBase:mah] is_a: FYPO:0004614 ! abnormal microtubule polymerization during vegetative growth created_by: midori creation_date: 2017-06-07T15:53:31Z [Term] id: FYPO:0006068 name: increased protein localization to endoplasmic reticulum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "increased protein localization to endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to ER" EXACT [PomBase:mah] is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth created_by: midori creation_date: 2017-06-09T14:23:50Z [Term] id: FYPO:0006069 name: increased small RNA binding def: "A molecular function phenotype in which an interaction between a protein and a small RNA (sRNA) is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PMID:28541282, PomBase:mah] synonym: "increased protein-small RNA interaction" EXACT [PomBase:mah] synonym: "increased small regulatory RNA binding" EXACT [SO:0000370] synonym: "increased sRNA binding" EXACT [PomBase:mah] is_a: FYPO:0002135 ! increased protein-RNA interaction created_by: midori creation_date: 2017-06-09T14:27:12Z [Term] id: FYPO:0006070 name: increased small RNA 3' adenylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more adenylyl residues to the 3' end of a small RNA (sRNA) molecule occurs to a greater extent than normal." [PMID:28541282, PomBase:mah] synonym: "increased small regulatory RNA 3' adenylation" EXACT [SO:0000370] synonym: "increased small RNA 3' adenylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased small RNA 3' adenylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased sRNA 3' adenylation" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2017-06-09T14:32:06Z [Term] id: FYPO:0006071 name: decreased small RNA 3' adenylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more adenylyl residues to the 3' end of a small RNA (sRNA) molecule occurs to a lower extent than normal." [PMID:28541282, PomBase:mah] synonym: "decreased small regulatory RNA 3' adenylation" EXACT [SO:0000370] synonym: "decreased small RNA 3' adenylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased small RNA 3' adenylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sRNA 3' adenylation" EXACT [PomBase:mah] synonym: "reduced small RNA 3' adenylation" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2017-06-09T14:36:12Z [Term] id: FYPO:0006072 name: abolished small RNA 3' uridylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the 3' end of a small RNA (sRNA) molecule does not occur." [PMID:28541282, PomBase:mah] synonym: "abolished small regulatory RNA 3' uridylation" EXACT [SO:0000370] synonym: "abolished small RNA 3' uridylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished small RNA 3' uridylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished sRNA 3' uridylation" EXACT [PomBase:mah] synonym: "small RNA 3' uridylation abolished" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2017-06-09T14:37:54Z [Term] id: FYPO:0006073 name: decreased small RNA degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process that specifically degrades small RNA molecules is decreased." [PMID:28541282, PomBase:mah] synonym: "decreased degradation of sRNA" EXACT [PomBase:al] synonym: "decreased small regulatory RNA 3' degradation" EXACT [SO:0000370] synonym: "decreased small RNA catabolic process" EXACT [PomBase:mah] synonym: "decreased small RNA catabolism" EXACT [PomBase:mah] synonym: "decreased small RNA degradation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased small RNA degradation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased sRNA 3' degradation" EXACT [PomBase:mah] synonym: "reduced small RNA degradation" EXACT [PomBase:mah] is_a: FYPO:0002137 ! decreased RNA catabolic process during vegetative growth created_by: midori creation_date: 2017-06-09T14:40:37Z [Term] id: FYPO:0006074 name: increased histone H3-K9 dimethylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at ribosomal DNA." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at rDNA during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation at rDNA during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at rDNA during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2017-06-09T14:47:33Z [Term] id: FYPO:0006075 name: increased mature 25S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 25S rRNA measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 25S rRNA level" BROAD [PomBase:mah] synonym: "increased mature 25S rRNA accumulation" RELATED [PomBase:mah] synonym: "increased mature 25S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature 25S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature 25S rRNA transcript level" EXACT [PomBase:vw] is_a: FYPO:0005996 ! altered rRNA or precursor level is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2017-06-09T14:49:30Z [Term] id: FYPO:0006076 name: siRNA absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature siRNA measured in a cell is too low to detect." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "siRNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "siRNA absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "small interfering RNA absent from cell" EXACT [PomBase:mah] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth is_a: FYPO:0004205 ! decreased siRNA level created_by: midori creation_date: 2017-06-09T14:52:05Z [Term] id: FYPO:0006077 name: increased histone H3-K9 methylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at ribosomal DNA." [PomBase:mah] synonym: "increased histone H3 K9 methylation at rDNA during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 methylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 methylation at rDNA during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 methylation at rDNA during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000871 ! increased histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2017-06-09T14:54:51Z [Term] id: FYPO:0006078 name: increased ribosomal RNA-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from ribosomal RNA are present at greater levels than normal." [PMID:28541282, PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of ribosomal RNA. synonym: "increased accumulation of ribosomal RNA-derived siRNA" EXACT [PomBase:mah] synonym: "increased accumulation of siRNAs homologous to ribosomal RNA" RELATED [PomBase:vw] synonym: "increased level of ribosomal RNA-derived siRNA" EXACT [PomBase:mah] synonym: "increased level of siRNAs homologous to rRNA" RELATED [PomBase:vw] synonym: "increased ribosomal RNA-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased ribosomal RNA-derived siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased rRNA-derived siRNA level" EXACT [PomBase:mah] is_a: FYPO:0004207 ! increased siRNA level created_by: midori creation_date: 2017-06-09T14:56:51Z [Term] id: FYPO:0006079 name: increased chromatin silencing at rDNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeat regions is increased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "increased chromatin silencing at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased chromatin silencing at ribosomal DNA" EXACT [PomBase:mah] is_a: FYPO:0000206 ! abnormal chromatin silencing at rDNA is_a: FYPO:0004540 ! increased chromatin silencing created_by: midori creation_date: 2017-06-09T14:59:33Z [Term] id: FYPO:0006080 name: normal protein localization to nuclear exosome focus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is normal (i.e. indistinguishable from wild type). Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1." [PMID:21317872, PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear exosome focus during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to Mmi1 focus during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to Mmi1 nuclear focus during vegetative growth" EXACT [GO:1990251] synonym: "normal protein localization to nuclear exosome foci during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to nuclear exosome focus during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-06-09T15:05:35Z [Term] id: FYPO:0006081 name: increased protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is increased." [PMID:20705466, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to actin patch" EXACT [PomBase:mah] synonym: "increased protein localization to F-actin patch" EXACT [PomBase:mah] is_a: FYPO:0000742 ! abnormal protein localization to actin cortical patch created_by: midori creation_date: 2017-06-09T15:10:55Z [Term] id: FYPO:0006082 name: normal actin filament depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament depolymerization, i.e. the removal of actin monomers from an actin filament, is normal (i.e. indistinguishable from wild type)." [GO:0030042, PomBase:mah] synonym: "normal actin filament depolymerisation" EXACT [PomBase:mah] synonym: "normal actin filament depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal microtubule actin filament during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization is_a: FYPO:0006003 ! normal cellular component organization created_by: midori creation_date: 2017-06-09T15:14:32Z [Term] id: FYPO:0006083 name: abnormal sporulation resulting in formation of ascus with four spores def: "A sporulation phenotype in which asci that contain four spores form following conjugation and subsequent sporulation, but sporulation is not entirely normal." [PMID:28011631, PomBase:mah] comment: Use this term if sporulation forms four-spored asci but is abnormal in some other respect. If all aspects of sporulation are normal, use 'normal sporulation (FYPO:0000590)'. synonym: "ascospore formation resulting in formation of asci with four spores" EXACT [GO:0030437, PomBase:mah] synonym: "normal spore number" EXACT [PomBase:vw] synonym: "sporulation resulting in formation of asci with four spores" EXACT [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2017-06-28T13:53:21Z [Term] id: FYPO:0006084 name: sensitive to cold shock def: "A cell phenotype in which cells show increased sensitivity to cold shock. Cold shock is a form of temperature stress in which cells are briefly exposed to a very low temperature." [PomBase:mah] synonym: "decreased growth during cellular response to cold shock" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to cold shock" EXACT [PomBase:mah] synonym: "hypersensitive to cold shock" EXACT [PomBase:mah] is_a: FYPO:0000080 ! decreased cell population growth at low temperature created_by: midori creation_date: 2017-06-28T14:06:50Z [Term] id: FYPO:0006085 name: normal snRNA pseudouridylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which intramolecular conversion of uridine to pseudouridine in an snRNA molecule is normal (i.e. indistinguishable from wild type)." [GO:0031120, PomBase:mah] synonym: "normal snRNA pseudouridine synthesis" EXACT [GO:0031120] synonym: "normal snRNA pseudouridylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal snRNA pseudouridylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-06-28T14:17:49Z [Term] id: FYPO:0006086 name: increased mitotic sister chromatid bridge formation during replication fork processing def: "A cell phenotype in which one or more bridges consisting of unresolved intertwined sister chromatids form following replication fork arrest, and persist until mitotic anaphase. Bridges contain dsDNA and RPA-bound ssDNA, and may break, resulting in unequal sister chromatid segregation." [PMID:28475874, PomBase:mah] synonym: "anaphase bridge formation following replication fork processing" RELATED [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2017-06-28T14:25:09Z [Term] id: FYPO:0006087 name: abolished DNA resection during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA resection does not occur upstream of a stalled replication fork. DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA." [PMID:28475874, PomBase:mah] synonym: "abolished DNA resection during replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished DNA resection during replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "abolished DNA resectioning during replication fork processing" EXACT [PomBase:amc] synonym: "abolished exonucleolytic DNA cleavage during replication fork processing" EXACT [PomBase:mah] synonym: "DNA resection during replication fork processing abolished" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2017-06-28T14:31:46Z [Term] id: FYPO:0006088 name: normal DNA binding during cellular response to DNA damage def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type) during a cellular response to DNA damage. The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal DNA binding in response to DNA damage" RELATED [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2017-06-28T14:33:58Z [Term] id: FYPO:0006089 name: abnormal glutathione hydrolase activity def: "A molecular function phenotype in which the observed rate of glutathione hydrolase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2017-06-30T10:57:40Z [Term] id: FYPO:0006090 name: increased glutathione hydrolase activity def: "A molecular function phenotype in which the observed rate of glutathione hydrolase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0006089 ! abnormal glutathione hydrolase activity created_by: midori creation_date: 2017-06-30T10:57:48Z [Term] id: FYPO:0006091 name: premature actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization begins earlier than normal. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell." [PMID:20705471, PomBase:mah] synonym: "advanced actin cortical patch internalization" EXACT [PomBase:mah] synonym: "premature actin cortical patch internalization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "premature actin patch internalization" EXACT [PomBase:mah] is_a: FYPO:0000743 ! abnormal actin cortical patch internalization created_by: midori creation_date: 2017-07-05T15:13:49Z [Term] id: FYPO:0006092 name: polarized actin cortical patch localization during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized more towards the end of the cell, with fewer patches in the lateral cortex, than normal." [PMID:20705471, PomBase:mah] synonym: "polarised actin cortical patch localisation during vegetative growth" EXACT [PomBase:mah] synonym: "polarized actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "polarized actin cortical patch location during vegetative growth" RELATED [PomBase:mah] synonym: "polarized actin patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "polarized F-actin patch localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003988 ! mislocalized actin cortical patches during vegetative growth created_by: midori creation_date: 2017-07-05T15:17:05Z [Term] id: FYPO:0006093 name: abnormal microfilament motor activity def: "A molecular function phenotype in which the observed rate or other property of a microfilament motor activity is abnormal." [PomBase:mah] synonym: "abnormal actin filament motor activity" EXACT [GO:0000146] synonym: "abnormal microfilament motor (ATPase) activity" EXACT [PomBase:vw] synonym: "abnormal myosin ATPase activity" RELATED [GO:0000146] is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2017-07-05T15:19:48Z [Term] id: FYPO:0006094 name: abnormal actin filament bundle assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles is abnormal." [GO:0061572, PomBase:mah] synonym: "abnormal actin bundling" EXACT [PomBase:mah] synonym: "abnormal actin filament bundle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin filament bundle assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2017-07-05T15:38:54Z [Term] id: FYPO:0006095 name: normal actin filament bundle assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin bundling" EXACT [PomBase:mah] synonym: "normal actin filament bundle assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actin filament bundle assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2017-07-05T15:42:06Z [Term] id: FYPO:0006096 name: abnormal protein localization to actin cable def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at actin cables and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actin cable" EXACT [PomBase:mah] synonym: "abnormal protein localization to actin cable during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to formin-nucleated actin cable" EXACT [GO:0070648] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2017-07-05T15:47:07Z [Term] id: FYPO:0006097 name: increased protein localization to actin cable def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is increased." [PMID:20705471, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to actin cable during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to formin-nucleated actin cable" EXACT [GO:0070648] is_a: FYPO:0006096 ! abnormal protein localization to actin cable created_by: midori creation_date: 2017-07-05T15:47:31Z [Term] id: FYPO:0006098 name: abnormal protein localization to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the cytoplasm is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cytoplasm" EXACT [PomBase:mah] synonym: "abnormal protein localization to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to cytoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2017-07-05T15:55:13Z [Term] id: FYPO:0006099 name: decreased protein localization to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cytoplasm" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cytoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0006098 ! abnormal protein localization to cytoplasm created_by: midori creation_date: 2017-07-05T15:56:11Z [Term] id: FYPO:0006100 name: decreased protein localization to cytoplasm, with protein mislocalized to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased, and some of the protein is present in the nucleus instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cytoplasm, with protein mislocalised to nucleus" EXACT [PomBase:mah] synonym: "decreased protein localization in cytoplasm, with protein mislocalized to nucleus" EXACT [GO:0034504] synonym: "decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cytoplasm, with protein mislocalized to nucleus" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth is_a: FYPO:0006099 ! decreased protein localization to cytoplasm relationship: has_part FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2017-07-05T16:03:02Z [Term] id: FYPO:0006101 name: abnormal interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the morphology of cytoplasmic microtubules is abnormal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "abnormal cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "abnormal interphase microtubule morphology" EXACT [PomBase:al] synonym: "abnormal interphase microtubule structure" NARROW [PomBase:mah] synonym: "abnormal interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004088 ! abnormal cytoplasmic microtubules created_by: midori creation_date: 2017-07-10T14:03:50Z [Term] id: FYPO:0006102 name: interphase microtubules absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable cytoplasmic microtubules during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "absent interphase microtubules" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules absent from cell during mitotic interphase" EXACT [PomBase:mah] synonym: "interphase cytoplasmic microtubules absent from cell" EXACT [PomBase:mah] synonym: "interphase microtubules absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "interphase microtubules absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004702 ! cytoplasmic microtubules absent from cell created_by: midori creation_date: 2017-07-10T14:50:43Z [Term] id: FYPO:0006103 name: short interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are shorter than normal during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "short cytoplasmic microtubules during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "short cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "short interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "short interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002760 ! short cytoplasmic microtubules is_a: FYPO:0003625 ! abnormal microtubule cytoskeleton morphology during mitotic interphase is_a: FYPO:0006101 ! abnormal interphase microtubules created_by: midori creation_date: 2017-07-10T15:28:42Z [Term] id: FYPO:0006104 name: decreased retrotransposon integration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of retrotransposon integration is decreased." [PMID:26358720, PomBase:mah] synonym: "decreased retrotransposon integration during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased retrotransposon integration during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transposon integration involved in RNA-mediated transposition" EXACT [GO:0120085] synonym: "reduced retrotransposon integration" EXACT [PomBase:mah] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2017-07-12T10:51:37Z [Term] id: FYPO:0006105 name: increased microtubule depolymerization at cell side def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the removal of tubulin dimers from a microtubule occurs to a greater extent than normal in the lateral part of the cell." [GO:0007019, PMID:26443240, PomBase:mah] synonym: "increased microtubule catastrophe at cell side" RELATED [PomBase:mah] synonym: "increased microtubule depolymerisation at cell side" EXACT [PomBase:mah] synonym: "increased microtubule depolymerization at cell side during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased microtubule depolymerization at cell side during vegetative growth" EXACT [PomBase:mah] synonym: "increased microtubule depolymerization at lateral part of cell" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth created_by: midori creation_date: 2017-07-12T10:56:06Z [Term] id: FYPO:0006106 name: abolished chromatin binding at centromere central core def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at the central core of the centromeric regions does not occur." [PomBase:mah] synonym: "chromatin binding at centromere central core abolished" EXACT [PomBase:mah] is_a: FYPO:0001093 ! abolished chromatin binding created_by: midori creation_date: 2017-07-12T11:12:32Z [Term] id: FYPO:0006107 name: mating, meiosis, and sporulation without starvation def: "A cellular process phenotype in which haploid cells mate and undergo meiotic nuclear division and sporulation in the presence of nutrients, notably nitrogen and glucose. Normally, fission yeast mate, undergo meiosis, and sporulate only under conditions of nitrogen and carbon starvation." [PMID:27613427, PomBase:mah] synonym: "conjugation, meiosis, and sporulation without starvation" EXACT [PomBase:mah] synonym: "deregulated sporulation" RELATED [PMID:27613427] synonym: "mating, meiotic nuclear division, and sporulation without starvation" EXACT [PomBase:mah] synonym: "meiotic cell cycle in presence of nutrients" EXACT [PomBase:mah] synonym: "meiotic cell cycle without starvation" EXACT [PomBase:mah] synonym: "sporulation in presence of nutrients" RELATED [PomBase:mah] is_a: FYPO:0000052 ! abnormal meiotic cell cycle created_by: midori creation_date: 2017-07-12T11:14:21Z [Term] id: FYPO:0006108 name: abnormal actin fusion focus assembly def: "A cellular process phenotype in which actin fusion focus assembly is abnormal. An actin fusion focus normally forms during mating at the site where the two cells will fuse." [PMID:28410370, PomBase:mah] synonym: "abnormal actin fusion focus formation" EXACT [PomBase:mah] is_a: FYPO:0004803 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2017-07-12T11:31:47Z [Term] id: FYPO:0006109 name: increased subtelomeric transcript-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from subtelomeric regions are present at greater levels than normal." [PMID:28404620, PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of RNA from the subtelomeric region. synonym: "increased accumulation of siRNAs homologous to subtelomeres" RELATED [PomBase:vw] synonym: "increased accumulation of subtelomeric transcript-derived siRNA" EXACT [PomBase:mah] synonym: "increased level of subtelomeric transcript-derived siRNA" EXACT [PomBase:mah] synonym: "increased subtelomere transcript-derived siRNA level" EXACT [PomBase:mah] synonym: "increased subtelomeric transcript-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased subtelomeric transcript-derived siRNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004207 ! increased siRNA level created_by: midori creation_date: 2017-07-12T11:39:55Z [Term] id: FYPO:0006110 name: increased silent mating-type cassette transcript-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the silent mating-type cassettes are present at greater levels than normal." [PMID:28404620, PomBase:mah] comment: This term refers specifically to siRNAs derived by dicer-mediated processing of RNA from the silent mating-type cassettes. synonym: "increased accumulation of silent mating-type cassette transcript-derived siRNA" EXACT [PomBase:mah] synonym: "increased accumulation of siRNAs homologous to silent mating-type cassette" RELATED [PomBase:vw] synonym: "increased level of silent mating-type cassette transcript-derived siRNA" EXACT [PomBase:mah] synonym: "increased mating-type region heterochromatin transcript-derived siRNA level" EXACT [PomBase:mah] synonym: "increased silent mating-type cassette transcript-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased silent mating-type cassette transcript-derived siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased silent mating-type region transcript-derived siRNA level" EXACT [PomBase:mah] is_a: FYPO:0004207 ! increased siRNA level created_by: midori creation_date: 2017-07-12T11:42:17Z [Term] id: FYPO:0006111 name: abolished histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in subtelomeric regions does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at subtelomeric region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me2 at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished subtelomeric histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0007886 ! abolished histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2017-07-12T11:50:08Z [Term] id: FYPO:0006112 name: abolished histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur." [PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K9me2 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished silent mating-type cassette histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent at silent mating-type cassette during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0004170 ! abolished histone H3-K9 dimethylation at centromere during vegetative growth is_a: FYPO:0007373 ! abnormal histone methylation at silent mating-type cassette during vegetative growth is_a: FYPO:0008212 ! abolished histone H3-K9 methylation at silent mating-type cassette during vegetative growth created_by: midori creation_date: 2017-07-12T11:50:43Z [Term] id: FYPO:0006113 name: obsolete increased chromatin-associated RNA level comment: OBSOLETE. Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. comment: This term was made obsolete because its meaning was unclear. is_obsolete: true [Term] id: FYPO:0006114 name: increased protein level during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during S phase of the mitotic cell cycle is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during mitotic S phase" RELATED [PomBase:mah] synonym: "increased protein level during mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during S phase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2017-07-12T13:56:34Z [Term] id: FYPO:0006115 name: increased protein oxidation during mitotic S phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins, during S phase of the mitotic cell cycle." [PMID:28640807, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "accumulation of carbonylated proteins during S phase during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of disulfides during mitotic S phase" RELATED [PomBase:al] synonym: "increased level of oxidised thiols in proteins during mitotic S phase" RELATED [PomBase:al] synonym: "increased level of oxidized protein thiols during mitotic S phase" RELATED [PomBase:mah] synonym: "increased protein oxidation during S phase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000219 ! increased protein oxidation during vegetative growth created_by: midori creation_date: 2017-07-12T13:57:34Z [Term] id: FYPO:0006116 name: abolished protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to actin cortical patch" EXACT [PomBase:mah] synonym: "abolished protein localization to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to actin patch" EXACT [PomBase:mah] synonym: "protein localization to actin cortical patch abolished" EXACT [PomBase:mah] is_a: FYPO:0000742 ! abnormal protein localization to actin cortical patch created_by: midori creation_date: 2017-07-12T14:10:22Z [Term] id: FYPO:0006117 name: multiseptate spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid and has two or more septa." [PomBase:mah] synonym: "multiseptate rounded vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0005149 ! septated spheroid vegetative cell relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2017-07-12T14:13:42Z [Term] id: FYPO:0006118 name: sensitive to 5-fluoroorotic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 5-fluoroorotic acid (5-FOA). Cells stop growing (and may die) at a concentration of 5-FOA that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 5-fluoroorotic acid" EXACT [PomBase:mah] synonym: "sensitive to 5-fluoroorotic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 5-fluoroorotic acid during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to 5-FOA" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-07-17T13:34:47Z [Term] id: FYPO:0006119 name: protein mislocalized to actin cable def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in or on actin cables is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at actin cables in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to actin cable" EXACT [PomBase:vw] synonym: "protein mislocalised to actin cable" EXACT [PomBase:mah] synonym: "protein mislocalised to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to actin cable during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to formin-nucleated actin cable" EXACT [GO:0070648] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2017-07-17T13:54:15Z [Term] id: FYPO:0006120 name: decreased protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to actin patch" EXACT [PomBase:mah] synonym: "reduced protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000742 ! abnormal protein localization to actin cortical patch created_by: midori creation_date: 2017-07-17T14:15:07Z [Term] id: FYPO:0006121 name: abnormal membrane raft distribution def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which membrane raft distribution, i.e. the process that establishes the spatial arrangement of membrane rafts within a cellular membrane, is abnormal." [GO:0031580, PMID:19808887, PomBase:mah] synonym: "abnormal lipid raft distribution" EXACT [GO:0031580] synonym: "abnormal membrane raft distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal membrane raft distribution during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2017-07-17T14:17:21Z [Term] id: FYPO:0006122 name: abnormal protein methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of one or more specific proteins is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein methylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2017-07-17T14:42:39Z [Term] id: FYPO:0006123 name: abolished asymmetric protein arginine dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine in one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished asymmetric protein arginine dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished peptidyl-arginine methylation, to asymmetrical-dimethyl arginine, during vegetative growth" EXACT [GO:0019919] synonym: "asymmetric protein arginine dimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "asymmetric protein arginine dimethylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth is_a: FYPO:0006122 ! abnormal protein methylation during vegetative growth created_by: midori creation_date: 2017-07-17T14:44:10Z [Term] id: FYPO:0006124 name: normal asymmetric protein arginine dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine in one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal asymmetric protein arginine dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal peptidyl-arginine methylation, to asymmetrical-dimethyl arginine, during vegetative growth" EXACT [GO:0019919] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2017-07-17T14:59:10Z [Term] id: FYPO:0006125 name: normal protein localization to nuclear body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a nuclear body is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear body" EXACT [PomBase:mah] synonym: "normal protein localization to nuclear body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nuclear body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-07-17T15:05:44Z [Term] id: FYPO:0006126 name: normal poly(A) RNA binding def: "A molecular function phenotype in which an interaction between a protein and polyadenylated RNA (poly(A) RNA) is normal (i.e. indistinguishable from wild type). One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "normal polyA RNA binding" EXACT [PomBase:mah] synonym: "normal polyadenylated RNA binding" EXACT [PomBase:mah] synonym: "normal protein-poly(A) RNA interaction" EXACT [PomBase:mah] is_a: FYPO:0002357 ! normal protein-RNA interaction created_by: midori creation_date: 2017-07-17T15:07:15Z [Term] id: FYPO:0006127 name: increased protein oligomerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oligomerization is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein oligomerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein oligomerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005220 ! abnormal protein oligomerization created_by: midori creation_date: 2017-07-17T15:09:55Z [Term] id: FYPO:0006128 name: normal duration of meiosis II def: "A cellular process phenotype in which the duration of the second meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of second meiotic nuclear division" EXACT [GO:0007135] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2017-07-19T11:14:09Z [Term] id: FYPO:0006129 name: obsolete decreased nuclear migration during mating def: "OBSOLETE. A cellular process phenotype in which the occurrence of nuclear migration involved in conjugation with cellular fusion is decreased." [PomBase:mah] comment: This term was made obsolete because the definition of the term was ambiguous. It was not clear whether it referred to nuclear congression or horsetail. synonym: "decreased nuclear migration involved in conjugation with cellular fusion" EXACT [GO:0000743] synonym: "decreased nuclear movement during mating" EXACT [PomBase:mah] synonym: "decreased nuclear movement during shmooing" RELATED [PomBase:vw] synonym: "reduced nuclear migration during mating" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0003062 consider: FYPO:0004605 created_by: midori creation_date: 2017-07-19T11:19:30Z [Term] id: FYPO:0006130 name: abolished protein localization to microtubule during meiosis def: "A cell phenotype in which the localization of a protein to one or more microtubules does not occur during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to microtubule during meiosis" EXACT [PomBase:mah] synonym: "abolished protein localization to microtubule during meiotic nuclear division" EXACT [GO:0140013] synonym: "protein absent from microtubule during meiosis" RELATED [PomBase:mah] synonym: "protein localization to microtubule abolished during meiosis" EXACT [PomBase:mah] is_a: FYPO:0004091 ! abolished protein localization to microtubule cytoskeleton created_by: midori creation_date: 2017-07-19T11:27:11Z [Term] id: FYPO:0006131 name: increased cellular gluconate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of gluconate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular gluconate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular gluconate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased gluconate accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T11:30:44Z [Term] id: FYPO:0006132 name: increased cellular mevalonate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mevalonate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular mevalonate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular mevalonate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mevalonate accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T11:35:04Z [Term] id: FYPO:0006133 name: increased cellular phytosphingosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytosphingosine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phytosphingosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phytosphingosine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased phytosphingosine accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T11:35:49Z [Term] id: FYPO:0006134 name: increased cellular 2-palmitoleoylglycerophosphoinositol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2-palmitoleoylglycerophosphoinositol measured in a cell is higher than normal." [PMID:28667014, PomBase:mah] synonym: "increased 2-palmitoleoylglycerophosphoinositol accumulation" RELATED [PomBase:al] synonym: "increased cellular 2-palmitoleoyl-sn-glycero-3-phospho-D-myo-inositol level during vegetative growth" EXACT [CHEBI:138108] synonym: "increased cellular 2-palmitoleoylglycerophosphoinositol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 2-palmitoleoylglycerophosphoinositol level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:22:57Z [Term] id: FYPO:0006135 name: increased cellular citrate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of citrate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular citrate anion level" EXACT [CHEBI:133748] synonym: "increased cellular citrate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular citrate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased citrate accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:27:21Z [Term] id: FYPO:0006136 name: increased cellular 2,3-butanediol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2,3-butanediol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased 2,3-butanediol accumulation" RELATED [PomBase:al] synonym: "increased cellular 2,3-butanediol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 2,3-butanediol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular butane-2,3-diol level" EXACT [CHEBI:62064] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:28:33Z [Term] id: FYPO:0006137 name: increased cellular 1-stearoylglycerophosphocholine (18:0) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-stearoylglycerophosphocholine (18:0) measured in a cell is higher than normal." [PMID:28667014, PomBase:mah] synonym: "increased 1-stearoylglycerophosphocholine (18:0) accumulation" RELATED [PomBase:al] synonym: "increased cellular 1-stearoyl-sn-glycero-3-phosphocholine level" EXACT [CHEBI:73858] synonym: "increased cellular 1-stearoylglycerophosphocholine (18:0) level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 1-stearoylglycerophosphocholine (18:0) level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:29:39Z [Term] id: FYPO:0006138 name: increased cellular cis-aconitate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cis-aconitate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular cis-aconitate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular cis-aconitate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular cis-aconitate(3-) anion level" EXACT [CHEBI:16383] synonym: "increased cis-aconitate accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:31:43Z [Term] id: FYPO:0006139 name: increased cellular 2-myristoylglycerophosphocholine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2-myristoylglycerophosphocholine measured in a cell is higher than normal." [PMID:28667014, PomBase:mah] synonym: "increased 2-myristoylglycerophosphocholine accumulation" RELATED [PomBase:al] synonym: "increased cellular 2-myristoylglycerophosphocholine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 2-myristoylglycerophosphocholine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular 2-tetradecanoyl-sn-glycero-3-phosphocholine level" EXACT [CHEBI:131738] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:32:47Z [Term] id: FYPO:0006140 name: increased cellular 1-eicosenoylglycerophosphocholine (20:1n9) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-eicosenoylglycerophosphocholine (20:1n9) measured in a cell is higher than normal." [PMID:28667014, PomBase:mah] synonym: "increased 1-eicosenoylglycerophosphocholine (20:1n9) accumulation" RELATED [PomBase:al] synonym: "increased cellular 1-(11Z)-icosenoyl-sn-glycero-3-phosphocholine level" EXACT [CHEBI:88685] synonym: "increased cellular 1-eicosenoylglycerophosphocholine (20:1n9) level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 1-eicosenoylglycerophosphocholine (20:1n9) level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-21T12:33:40Z [Term] id: FYPO:0006141 name: abolished cell population growth on gluconate carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing gluconate as the carbon source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with gluconate as the carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished gluconate utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished growth on gluconate carbon source" BROAD [PomBase:mah] synonym: "abolished vegetative cell population growth on gluconate carbon source" EXACT [PomBase:mah] synonym: "cell population growth on gluconate carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth is_a: FYPO:0001830 ! decreased cell population growth on gluconate carbon source created_by: midori creation_date: 2017-07-21T12:39:12Z [Term] id: FYPO:0006142 name: normal G0 to G1 transition def: "A cellular process phenotype in which the transition from G0 phase (quiescence) to G1 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal exit from cell quiescence" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2017-07-24T14:11:14Z [Term] id: FYPO:0006143 name: obsolete delayed onset of protein tyrosine dephosphorylation during vegetative growth def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of protein tyrosine residues begins later than normal. All protein tyrosine dephosphorylation may be affected, or tyrosine residues in one or more specific proteins, or at specific protein sites, or even specific sites within specific proteins." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "delayed onset of peptidyl-tyrosine dephosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein tyrosine dephosphorylation during mitotic cell cycle" RELATED [GO:0035335] synonym: "delayed protein tyrosine dephosphorylation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0002830 created_by: midori creation_date: 2017-07-24T14:13:49Z [Term] id: FYPO:0006144 name: decreased cellular gluconate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of gluconate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular gluconate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular gluconate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased gluconate accumulation" RELATED [PomBase:al] synonym: "reduced cellular gluconate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-07-31T14:06:04Z [Term] id: FYPO:0006145 name: decreased RNA level during cellular response to copper ion during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ions is lower than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected." [PMID:24569997, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to copper ion during meiotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased RNA level during meiotic cell cycle during copper excess" RELATED [PomBase:vw] synonym: "decreased transcript level during cellular response to copper ion during meiotic cell cycle" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to copper ion during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle created_by: midori creation_date: 2017-07-31T14:09:41Z [Term] id: FYPO:0006146 name: normal RNA level during cellular response to copper ion starvation during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ion starvation and during the meiotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:24569997, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal cellular RNA level during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "normal mRNA level during cellular response to copper ion starvation during meiotic cell cycle" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to copper ion starvation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during meiotic cell cycle during copper starvation" EXACT [PomBase:vw] synonym: "normal transcript level during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0006976 ! normal RNA level during meiotic cell cycle created_by: midori creation_date: 2017-07-31T14:13:28Z [Term] id: FYPO:0006147 name: decreased level of early meiotic gene mRNA during cellular response to copper ion starvation during meiotic cell cycle def: "A cell phenotype in which the amount of RNA transcribed from early meiotic genes measured in a cell is lower than normal during a cellular response to copper ion starvation during the meiotic cell cycle. Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination." [PMID:24569997, PomBase:al, PomBase:mah] synonym: "decreased level of early meiosis gene mRNA during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of early meiotic gene RNA during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of early meiotic gene transcripts during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:vw] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle created_by: midori creation_date: 2017-07-31T14:18:20Z [Term] id: FYPO:0006148 name: abolished transcription during nitrogen starvation def: "A cellular process phenotype in which transcription does not occur when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "abolished nitrogen deprivation induced gene expression" RELATED [PomBase:vw] synonym: "abolished transcription during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished transcription during nitrogen depletion" EXACT [PomBase:vw] synonym: "abolished transcription during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abolished transcription during nitrogen limitation" EXACT [PomBase:mah] synonym: "abolished transcription during nitrogen starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished transcription during nitrogen starvation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished transcription in response to nitrogen starvation" EXACT [PomBase:vw] synonym: "transcription abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0002877 ! abolished transcription is_a: FYPO:0005118 ! decreased transcription during nitrogen starvation created_by: midori creation_date: 2017-07-31T14:25:39Z [Term] id: FYPO:0006149 name: sensitive to idarubicin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to idarubicin. Cells stop growing (and may die) at a concentration of idarubicin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to idarubicin" EXACT [PomBase:mah] synonym: "sensitive to idarubicin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to idarubicin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-07-31T14:30:08Z [Term] id: FYPO:0006150 name: normal growth on etoposide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing etoposide." [PomBase:mah] synonym: "normal cell population growth in presence of etoposide" EXACT [PomBase:mah] synonym: "normal cell population growth on etoposide" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to etoposide" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on etoposide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2017-07-31T14:31:00Z [Term] id: FYPO:0006151 name: abnormal SUMO-specific protease activity def: "A molecular function phenotype in which the observed rate of SUMO-specific protease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2017-07-31T14:31:55Z [Term] id: FYPO:0006152 name: decreased SUMO-specific protease activity def: "A molecular function phenotype in which the observed rate of SUMO-specific protease activity is decreased." [PomBase:mah] synonym: "reduced SUMO-specific protease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0006151 ! abnormal SUMO-specific protease activity created_by: midori creation_date: 2017-07-31T14:32:11Z [Term] id: FYPO:0006153 name: abolished DNA binding at STREP motif def: "A molecular function phenotype in which DNA binding at a STREP motif by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished DNA binding at stress-starvation response element of Schizosaccharomyces pombe" EXACT [SO:0001859] synonym: "DNA binding at STREP motif abolished" EXACT [PomBase:mah] synonym: "STREP motif binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2017-07-31T14:44:29Z [Term] id: FYPO:0006154 name: increased level of pheromone response gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pheromone response mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Pheromone response genes are normally transcribed in response to a pheromone stimulus." [PMID:22900017, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of pheromone response gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of pheromone response gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of pheromone response gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased pheromone response gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2017-07-31T14:47:33Z [Term] id: FYPO:0006155 name: increased level of mating gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more mating mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Mating genes are normally transcribed during conjugation with cellular fusion (i.e. mating)." [PMID:19056896, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of conjugation gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of mating gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of mating gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of mating gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of mating with cellular fusion gene mRNA during vegetative growth" EXACT [GO:0000743] synonym: "increased mating gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2017-07-31T14:51:49Z [Term] id: FYPO:0006156 name: sensitive to sodium arsenite def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium arsenite (AsNaO2). Cells stop growing (and may die) at a concentration of sodium arsenite that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium arsenite" EXACT [PomBase:mah] synonym: "sensitive to AsNaO2" EXACT [CHEBI:29678] synonym: "sensitive to sodium arsenite during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium arsenite during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-08-01T12:19:39Z [Term] id: FYPO:0006157 name: increased duration of protein oxidation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of oxidation of one or more specific proteins, or of specific protein sites is longer than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein oxidation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "prolonged protein oxidation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification during vegetative growth created_by: midori creation_date: 2017-08-04T11:03:08Z [Term] id: FYPO:0006158 name: normal RNA level during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during mitotic S phase" NARROW [PomBase:mah] synonym: "normal RNA accumulation during mitotic S phase" RELATED [PomBase:mah] synonym: "normal RNA level during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal transcript level during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2017-08-04T11:06:57Z [Term] id: FYPO:0006159 name: increased protein localization to linear element def: "A cell phenotype in which the localization of a protein to linear elements is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to linear element" EXACT [GO:0036181, PomBase:mah] is_a: FYPO:0000909 ! abnormal protein localization to linear element created_by: midori creation_date: 2017-08-04T11:20:07Z [Term] id: FYPO:0006160 name: decreased number of Rad51 foci during meiotic prophase I def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad51 accumulates is lower than normal during prophase of the first meiotic nuclear division." [PMID:16532353, PomBase:mah] synonym: "decreased number of Rad51 foci during prophase I" EXACT [PomBase:mah] synonym: "reduced number of Rad51 foci during prophase I" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2017-08-04T11:21:23Z [Term] id: FYPO:0006161 name: abolished protein localization to chromatin during meiosis I def: "A cell phenotype in which the localization of a protein to chromatin is abolished during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "protein localization to chromatin during meiosis I replication abolished" EXACT [PomBase:mah] is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2017-08-04T11:29:53Z [Term] id: FYPO:0006162 name: normal protein localization to chromatin during meiosis I def: "A cell phenotype in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0006163 ! normal protein localization to chromatin created_by: midori creation_date: 2017-08-04T11:32:31Z [Term] id: FYPO:0006163 name: normal protein localization to chromatin def: "A cell phenotype in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2017-08-04T11:32:59Z [Term] id: FYPO:0006164 name: decreased protein localization to linear element def: "A cell phenotype in which the localization of a protein to linear elements is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to linear element" EXACT [GO:0036181, PomBase:mah] synonym: "reduced protein localization to linear element" EXACT [PomBase:mah] is_a: FYPO:0000909 ! abnormal protein localization to linear element created_by: midori creation_date: 2017-08-04T11:39:07Z [Term] id: FYPO:0006165 name: branched, swollen, elongated, multinucleate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched, has more than one nucleus, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:jh, PomBase:mah] synonym: "branched, elongated, swollen, multinucleate vegetative cell" EXACT [PomBase:mah] synonym: "branched, swollen, elongated, multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, swollen, elongated, multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell is_a: FYPO:0001429 ! swollen elongated cell is_a: FYPO:0001512 ! branched, elongated cell is_a: FYPO:0004257 ! swollen multinucleate vegetative cell created_by: midori creation_date: 2017-08-04T13:32:21Z [Term] id: FYPO:0006166 name: inviable branched, swollen, elongated, multinucleate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, has more than one nucleus, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:jh, PomBase:mah] synonym: "inviable branched, elongated, swollen, multinucleate vegetative cell" EXACT [PomBase:vw] synonym: "inviable branched, swollen, elongated, multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, swollen, elongated, multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; branched, swollen, elongated, multinucleate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0004494 ! inviable branched, swollen, elongated vegetative cell is_a: FYPO:0006165 ! branched, swollen, elongated, multinucleate vegetative cell created_by: midori creation_date: 2017-08-04T13:32:48Z [Term] id: FYPO:0006167 name: viable branched, swollen, elongated, multinucleate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, has more than one nucleus, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:jh, PomBase:mah] synonym: "viable branched, elongated, swollen, multinucleate vegetative cell" EXACT [PomBase:vw] synonym: "viable branched, swollen, elongated, multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, swollen, elongated, multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001495 ! viable elongated multinucleate vegetative cell is_a: FYPO:0002479 ! viable swollen elongated vegetative cell is_a: FYPO:0006165 ! branched, swollen, elongated, multinucleate vegetative cell is_a: FYPO:0007282 ! viable branched, swollen vegetative cell created_by: midori creation_date: 2017-08-04T13:32:54Z [Term] id: FYPO:0006168 name: normal protein phosphorylation during cellular response to paraquat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to paraquat." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to paraquat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to paraquat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2017-08-04T14:01:07Z [Term] id: FYPO:0006169 name: normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to 4-nitroquinoline N-oxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to 4-NQO" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to 4NQO" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: midori creation_date: 2017-08-04T14:01:49Z [Term] id: FYPO:0006170 name: decreased RNA level during cellular response to copper ion starvation during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected." [PMID:24569997, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to copper ion starvation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper starvation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased RNA level during meiotic cell cycle during copper starvation" RELATED [PomBase:vw] synonym: "decreased transcript level during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to copper ion starvation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004630 ! decreased RNA level during meiotic cell cycle is_a: FYPO:0006209 ! decreased RNA level during cellular response to copper ion starvation created_by: midori creation_date: 2017-08-07T11:44:48Z [Term] id: FYPO:0006171 name: mitotic spindle elongation during anaphase A def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation takes place during anaphase A. Normally, the spindle elongates immediately following assembly during prophase, remains at a static length during metaphase and anaphase A, and elongates further during anaphase B." [PMID:21920317, PMID:9802907, PomBase:mah] synonym: "abnormal mitotic spindle elongation during anaphase A" EXACT [PomBase:mah] synonym: "mitotic spindle elongation during anaphase A during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle extension during anaphase A" EXACT [PomBase:vw] synonym: "premature mitotic spindle elongation during anaphase" RELATED [PomBase:mah] synonym: "spindle elongation during anaphase A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle elongation during mitotic anaphase A" EXACT [PomBase:mah] is_a: FYPO:0005417 ! premature mitotic spindle elongation created_by: midori creation_date: 2017-08-07T11:52:20Z [Term] id: FYPO:0006172 name: mitotic spindle collapse without elongation during anaphase B def: "A cell phenotype in which a short mitotic spindle assembles and elongates during prophase, but does not elongate further during anaphase B and eventually collapses." [PMID:25375240, PomBase:mah] synonym: "broken mitotic spindle without elongation during anaphase B" RELATED [PomBase:vw] synonym: "mitotic spindle breakage without elongation during anaphase B" EXACT [PomBase:vw] synonym: "mitotic spindle collapse without elongation during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle collapse without extension during anaphase B" EXACT [PomBase:vw] synonym: "spindle collapse without elongation during anaphase B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle collapse without elongation during mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0006174 ! abolished mitotic spindle elongation during anaphase B is_a: FYPO:0006475 ! mitotic spindle collapse relationship: has_part FYPO:0006174 ! abolished mitotic spindle elongation during anaphase B created_by: midori creation_date: 2017-08-07T12:04:25Z [Term] id: FYPO:0006173 name: abolished mitotic spindle elongation during prophase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation does not occur during prophase. Normally, the spindle elongates immediately following assembly during prophase, remains at a static length during metaphase and anaphase A, and elongates further during anaphase B." [PMID:21920317, PomBase:mah] synonym: "abolished spindle elongation during mitotic prophase" EXACT [PomBase:mah] synonym: "abolished spindle elongation during prophase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic spindle elongation abolished during prophase" EXACT [PomBase:mah] synonym: "mitotic spindle elongation abolished during prophase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003829 ! abolished mitotic spindle elongation created_by: midori creation_date: 2017-08-07T12:04:37Z [Term] id: FYPO:0006174 name: abolished mitotic spindle elongation during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation does not occur during anaphase B. Normally, the spindle elongates immediately following assembly during prophase, remains at a static length during metaphase and anaphase A, and elongates further during anaphase B." [PMID:21920317, PomBase:mah] synonym: "abolished mitotic spindle extension during anaphase B" EXACT [PomBase:vw] synonym: "abolished spindle elongation during anaphase B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished spindle elongation during mitotic anaphase B" EXACT [PomBase:mah] synonym: "mitotic spindle elongation abolished during anaphase B" EXACT [PomBase:mah] synonym: "mitotic spindle elongation abolished during anaphase B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003829 ! abolished mitotic spindle elongation created_by: midori creation_date: 2017-08-07T12:08:16Z [Term] id: FYPO:0006175 name: abnormal protein localization to centromere during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is abnormal during metaphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to centromere during mitotic metaphase" EXACT [PomBase:mah] synonym: "abnormal protein localisation to chromosome, centromeric region during mitotic metaphase" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to centromere during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromosome, centric region during mitotic metaphase" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centromeric region during mitotic metaphase" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere during vegetative growth created_by: midori creation_date: 2017-08-07T12:28:53Z [Term] id: FYPO:0006176 name: decreased rate of actin cortical patch localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cortical patch localization is decreased." [PomBase:mah] synonym: "decreased rate of actin cortical patch localisation" EXACT [PomBase:mah] synonym: "decreased rate of actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actin cortical patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of actin cortical patch movement" RELATED [PomBase:mah] synonym: "decreased rate of actin patch localization" EXACT [PomBase:vw] synonym: "reduced rate of actin cortical patch localization" EXACT [PomBase:mah] is_a: FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth created_by: midori creation_date: 2017-08-07T13:17:13Z [Term] id: FYPO:0006177 name: undirected actin cortical patch movement def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches move within the cell cortex in a less directed manner than normal. The rate of movement may be normal." [PMID:11231572, PomBase:mah] synonym: "undirected actin cortical patch localization" RELATED [PomBase:mah] synonym: "undirected actin patch movement" EXACT [PomBase:mah] is_a: FYPO:0000190 ! abnormal actin cortical patch localization during vegetative growth created_by: midori creation_date: 2017-08-07T13:17:31Z [Term] id: FYPO:0006178 name: normal rate of actin cortical patch localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cortical patch localization is normal (i.e. indistinguishable from wild type)." [PMID:11231572, PomBase:mah] synonym: "normal rate of actin cortical patch localisation" EXACT [PomBase:mah] synonym: "normal rate of actin cortical patch localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of actin cortical patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of actin patch localization" EXACT [PomBase:mah] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2017-08-07T13:53:46Z [Term] id: FYPO:0006179 name: abnormal lateral attachment of mitotic spindle microtubules to kinetochore def: "A cellular process phenotype in which the lateral attachment of sister chromatids to mitotic spindle microtubules is abnormal. Normally, sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate)." [GO:0099607, PomBase:mah] synonym: "abnormal lateral attachment of mitotic spindle microtubules to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal lateral attachment of spindle microtubules to kinetochore during mitosis" EXACT [PomBase:mah] synonym: "abnormal lateral attachment of spindle microtubules to kinetochore during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore created_by: midori creation_date: 2017-08-09T12:00:50Z [Term] id: FYPO:0006180 name: increased microtubule polymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers, occurs to a greater extent than normal." [GO:0046785, PomBase:mah] synonym: "increased microtubule growth" EXACT [PomBase:vw] synonym: "increased microtubule polymerisation" EXACT [PomBase:mah] synonym: "increased microtubule polymerization" RELATED [PomBase:mah] synonym: "increased microtubule polymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased microtubule polymerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004614 ! abnormal microtubule polymerization during vegetative growth created_by: midori creation_date: 2017-08-09T12:15:02Z [Term] id: FYPO:0006181 name: decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased, and some of the protein is present in the nucleus instead, during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cytoplasm, with protein mislocalised to nucleus, during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localization in cytoplasm, with protein mislocalized to nucleus, during mitotic interphase" EXACT [GO:0034504] synonym: "decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during mitotic interphase, during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cytoplasm, with protein mislocalized to nucleus, during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0006100 ! decreased protein localization to cytoplasm, with protein mislocalized to nucleus created_by: midori creation_date: 2017-08-09T12:22:34Z [Term] id: FYPO:0006182 name: decreased protein localization to interphase microtubule def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a cytoplasmic microtubule is decreased during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cytoplasmic microtubule during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localisation to interphase microtubule" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasmic microtubule during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasmic microtubule during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasmic microtubule during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to interphase cytoplasmic microtubule" EXACT [PomBase:mah] synonym: "decreased protein localization to interphase microtubule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to interphase microtubule during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to interphase microtubule" EXACT [PomBase:mah] is_a: FYPO:0000933 ! decreased protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2017-08-09T13:22:31Z [Term] id: FYPO:0006183 name: abnormal protein localization to nucleus during meiotic prophase I def: "A cell phenotype in which the localization of a protein to the nucleus is abnormal during prophase of the first meiotic nuclear division." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the nucleus and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleus during meiotic prophase I" EXACT [GO:0034504, PomBase:mah] synonym: "abnormal protein localization to nucleus during prophase I" EXACT [PomBase:mah] is_a: FYPO:0002956 ! abnormal protein localization to nucleus created_by: midori creation_date: 2017-08-09T13:42:19Z [Term] id: FYPO:0006184 name: altered level of osmotic stress responsive gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to osmotic stress measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells during vegetative growth)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "abnormal level of osmotic stress responsive gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of cellular response to osmotic stress responsive gene mRNA" EXACT [PomBase:al] synonym: "altered level of osmotic stress responsive gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered level of osmotic stress responsive gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "altered level of osmotic stress responsive gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "altered mRNA level of osmotic stress responsive genes during vegetative growth" EXACT [PomBase:al] synonym: "altered osmotic stress responsive gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0004363 ! altered level of stress responsive gene mRNA during vegetative growth created_by: midori creation_date: 2017-08-09T14:18:20Z [Term] id: FYPO:0006185 name: decreased protein localization to nucleus during prophase I def: "A cell phenotype in which the localization of a protein to the nucleus is decreased during prophase of the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during prophase I" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during prophase I" EXACT [PomBase:mah] is_a: FYPO:0004455 ! decreased protein localization to nucleus is_a: FYPO:0006183 ! abnormal protein localization to nucleus during meiotic prophase I created_by: midori creation_date: 2017-08-14T14:10:01Z [Term] id: FYPO:0006186 name: increased rate of actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of contractile ring assembly is increased. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins." [PomBase:mah] synonym: "increased rate of actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of contractile ring assembly" EXACT [PomBase:mah] synonym: "increased rate of cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "increased rate of mitotic contractile ring assembly" EXACT [PomBase:mah] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly created_by: midori creation_date: 2017-08-14T14:19:49Z [Term] id: FYPO:0006187 name: normal rate of actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring assembly is normal (i.e. indistinguishable from wild type). Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins." [GO:1903475, PomBase:mah] synonym: "normal rate of actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal rate of actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of contractile ring assembly" EXACT [PomBase:vw] synonym: "normal rate of cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "normal rate of mitotic actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "normal rate of mitotic contractile ring assembly" EXACT [PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-08-14T14:20:46Z [Term] id: FYPO:0006188 name: decreased rate of protein exchange in actomyosin contractile ring def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the actomyosin contractile ring is decreased. Normally, proteins including actin and myosin are turned over between the contractile ring and elsewhere in the cytoplasm; exchange is faster during than before ring constriction." [PMID:19570908, PMID:20110347, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased rate of protein exchange in actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of protein exchange in actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of protein exchange in actomyosin contractile ring" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004738 ! abnormal actomyosin contractile ring organization is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2017-08-14T14:24:36Z [Term] id: FYPO:0006189 name: normal protein localization to actin cable def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is normal (i.e. indistinguishable from wild type). Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to actin cable" EXACT [PomBase:mah] synonym: "normal protein localization to actin cable during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to actin cable during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to formin-nucleated actin cable" EXACT [GO:0070648] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-08-14T14:40:34Z [Term] id: FYPO:0006190 name: long mitotic spindle during anaphase A def: "A spindle phenotype in which the mitotic spindle is longer than normal during anaphase A." [PMID:12426374, PomBase:mah] synonym: "elongated mitotic spindle during anaphase A" EXACT [PomBase:mah] synonym: "increased mitotic spindle length during anaphase A" EXACT [PomBase:vw] synonym: "long bipolar mitotic spindle during anaphase A" EXACT [PomBase:vw] synonym: "long mitotic spindle during anaphase A during vegetative growth" EXACT [PomBase:mah] synonym: "long mitotic spindles during anaphase A" EXACT [PomBase:mah] synonym: "long spindle during anaphase A of mitosis" EXACT [PomBase:mah] synonym: "long spindle during mitotic anaphase A" EXACT [PomBase:mah] is_a: FYPO:0004438 ! long mitotic spindle during anaphase created_by: midori creation_date: 2017-08-14T14:56:21Z [Term] id: FYPO:0006191 name: decreased protein localization to nucleus, with protein mislocalized to cytoplasm during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased, and some of the protein is present in the cytoplasm instead, during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus, with protein mislocalised to cytoplasm during mitosis" EXACT [PomBase:mah] synonym: "decreased protein localization in nucleus, with protein mislocalized to cytoplasm during mitosis" EXACT [GO:0034504] synonym: "decreased protein localization to nucleus, with protein mislocalized to cytoplasm, during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus, with protein mislocalized to cytoplasm, during mitotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus, with protein mislocalized to cytoplasm during mitosis" EXACT [PomBase:mah] is_a: FYPO:0004056 ! decreased protein localization to nucleus, with protein mislocalized to cytoplasm is_a: FYPO:0005672 ! decreased protein localization to nucleus during mitosis created_by: midori creation_date: 2017-08-14T14:58:12Z [Term] id: FYPO:0006192 name: normal volume aseptate spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, has no septum, and has a normal volume." [PomBase:mah] synonym: "normal volume aseptate rounded vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000946 ! normal volume spheroid vegetative cell is_a: FYPO:0000949 ! aseptate relationship: has_part FYPO:0000949 ! aseptate created_by: midori creation_date: 2017-08-16T10:59:43Z [Term] id: FYPO:0006193 name: normal shmoo morphology def: "A physical cellular phenotype in which the size, shape, or structure of the mating projection is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal conjugation tube morphology" EXACT [PomBase:mah] synonym: "normal mating projection morphology" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component relationship: output_of FYPO:0000573 ! normal shmoo formation created_by: midori creation_date: 2017-08-16T11:03:38Z [Term] id: FYPO:0006194 name: inviable after spore germination, single or double cell division, spherical cell with cell lysis def: "A phenotype in which a spore germinates to produce a cell that is spherical, and undergoes one or two rounds of cell division before all cells die, and some cells lyse." [PMID:12456722, PomBase:mah] synonym: "inviable following spore germination, single or double cell division, spherical cell with cell lysis" EXACT [PomBase:mah] synonym: "inviable germinated spore, single or double cell division, spherical cell with cell lysis" EXACT [PomBase:mah] synonym: "lethal after spore germination, single or double cell division, spherical cell with cell lysis" EXACT [PomBase:mah] is_a: FYPO:0002421 ! inviable after spore germination, single or double cell division, abnormal cell shape created_by: midori creation_date: 2017-08-16T11:15:38Z [Term] id: FYPO:0006195 name: decreased number of elongated microtubule bundles curved around cell end def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which all detectable microtubules are present in fewer bundles than normal (usually only one or two), and bundles are longer than normal and curved around one or both ends of the cell." [PMID:14742702, PMID:16481403, PomBase:mah, PomBase:vw] comment: Curved microtubules follow a smooth bend rather than a straight line. This phenotype is observed during interphase of the mitotic cell cycle. synonym: "decreased number of elongated interphase microtubule bundles curved around cell end" EXACT [PomBase:mah] synonym: "decreased number of elongated microtubule bundles curved around cell end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of elongated microtubule bundles curved around cell end during vegetative growth" EXACT [PomBase:mah] synonym: "decreased number of elongated microtubule bundles curved around cell tip" EXACT [PomBase:mah] synonym: "decreased number of elongated microtubule bundles curved around end of cell" EXACT [PomBase:vw] synonym: "decreased number of elongated MT bundles curved around cell end" EXACT [PomBase:mah] synonym: "decreased number of microtubule arrays curved around cell end" RELATED [PomBase:vw] synonym: "single elongated microtubule bundle curved around cell end" NARROW [PomBase:mah] is_a: FYPO:0004511 ! long curved interphase microtubules is_a: FYPO:0005558 ! abnormal microtubule bundle relationship: has_part FYPO:0005880 ! long interphase microtubules curved around cell end created_by: midori creation_date: 2017-08-16T11:20:43Z [Term] id: FYPO:0006196 name: short misoriented interphase microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are shorter than normal and have abnormal orientation. The normal orientation is parallel to the long axis of the cell." [PMID:11432827, PomBase:mah] synonym: "short misoriented cytoplasmic microtubules during mitotic interphase" EXACT [PomBase:mah] synonym: "short misoriented interphase cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "short misoriented interphase microtubules during mitotic cell cycle" RELATED [PomBase:mah] synonym: "short misoriented interphase microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth relationship: has_part FYPO:0003328 ! misoriented interphase microtubules relationship: has_part FYPO:0006103 ! short interphase microtubules created_by: midori creation_date: 2017-08-16T13:50:18Z [Term] id: FYPO:0006197 name: inviable mononucleate vegetative cell, with normal cell length and increased cell diameter def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, has one nucleus, and has normal length but a greater diameter than normal." [PMID:20805322, PomBase:mah] synonym: "inviable mononucleate cell, with normal cell length and increased cell diameter, during vegetative growth" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell, with increased cell diameter and normal cell length" EXACT [PomBase:mah] synonym: "inviable mononucleate vegetative cell, with normal cell length and increased cell diameter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable mononucleate vegetative cell, with normal length and increased diameter" EXACT [PomBase:mah] synonym: "inviable swollen mononucleate vegetative cell, with normal cell length" RELATED [PomBase:mah] synonym: "lethal; mononucleate vegetative cell, with normal cell length and increased cell diameter" EXACT [PomBase:mah] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0002199 ! inviable vegetative cell with normal cell morphology is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0003503 ! normal vegetative cell length relationship: has_part FYPO:0000060 ! mononucleate vegetative cell relationship: has_part FYPO:0003503 ! normal vegetative cell length created_by: midori creation_date: 2017-08-29T13:16:57Z [Term] id: FYPO:0006198 name: inviable binucleate vegetative cell, with normal cell length and increased cell diameter def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, has two nuclei, and has normal length but a greater diameter than normal." [PMID:20805322, PomBase:mah] comment: When using this term, also consider annotating to a cell cycle arrest term, such as 'abnormal cell cycle arrest in mitotic telophase' (FYPO:0000622); 'abnormal cell cycle arrest in mitotic anaphase' (FYPO:0000619) may be applicable if the assay detects DNA masses. Binucleate cells often arise as a result of cell cycle arrest. synonym: "inviable binucleate cell, with normal cell length and increased cell diameter, during vegetative growth" EXACT [PomBase:mah] synonym: "inviable binucleate vegetative cell, with increased cell diameter and normal cell length" EXACT [PomBase:mah] synonym: "inviable binucleate vegetative cell, with normal cell length and increased cell diameter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable binucleate vegetative cell, with normal length and increased diameter" EXACT [PomBase:mah] synonym: "inviable swollen binucleate vegetative cell, with normal cell length" RELATED [PomBase:mah] synonym: "lethal; binucleate vegetative cell, with normal cell length and increased cell diameter" EXACT [PomBase:mah] is_a: FYPO:0001222 ! binucleate vegetative cell is_a: FYPO:0002199 ! inviable vegetative cell with normal cell morphology is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0003503 ! normal vegetative cell length relationship: has_part FYPO:0001222 ! binucleate vegetative cell relationship: has_part FYPO:0003503 ! normal vegetative cell length created_by: midori creation_date: 2017-08-29T13:22:16Z [Term] id: FYPO:0006199 name: inviable stubby multinucleate vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable and has more than one nucleus, and the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable stubby multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable stubby multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable watermelon-shaped multinucleate vegetative cell" EXACT [PomBase:mah] synonym: "lethal; stubby multinucleate vegetative cell" EXACT [PomBase:mah] synonym: "stubby multinucleate inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0002107 ! inviable stubby vegetative cell relationship: has_part FYPO:0000061 ! multinucleate vegetative cell created_by: midori creation_date: 2017-08-29T13:23:12Z [Term] id: FYPO:0006200 name: sensitive to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phosphate starvation." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to calcium starvation in culture. If you have assayed the response to calcium starvation at the subcellular or molecular level, consider annotating to 'abnormal cellular response to calcium starvation' (FYPO:0001200). synonym: "decreased growth during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "hypersensitive to phosphate starvation" EXACT [PomBase:mah] synonym: "reduced growth in low phosphate" RELATED [PomBase:vw] synonym: "sensitive to phosphate depletion" EXACT [PomBase:vw] synonym: "sensitive to phosphate deprivation" EXACT [PomBase:vw] synonym: "sensitive to phosphate ion starvation" EXACT [PomBase:mah] synonym: "sensitive to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to phosphate starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2017-09-04T14:13:57Z [Term] id: FYPO:0006201 name: abnormal regulation of adenine biosynthetic process def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of an adenine biosynthetic process is abnormal." [PomBase:mah] synonym: "abnormal regulation of adenine anabolism" EXACT [GO:0046084] synonym: "abnormal regulation of adenine biosynthesis" EXACT [GO:0046084] synonym: "abnormal regulation of adenine biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of adenine biosynthetic process during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of adenine formation" EXACT [GO:0046084] synonym: "abnormal regulation of adenine synthesis" EXACT [GO:0046084] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2017-09-04T14:31:49Z [Term] id: FYPO:0006202 name: normal RNA level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydroxyurea is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to hydroxyurea" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to HU" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcript level during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2017-09-04T14:39:21Z [Term] id: FYPO:0006203 name: decreased cellular dATP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dATP measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular dATP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular dATP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular dATP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-09-04T14:41:26Z [Term] id: FYPO:0006204 name: normal cellular dCTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dCTP measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular dCTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular dCTP level during vegetative growth" EXACT [PomBase:mah] synonym: "normal dCTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2017-09-04T14:42:30Z [Term] id: FYPO:0006205 name: normal cellular dGTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dGTP measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular dGTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular dGTP level during vegetative growth" EXACT [PomBase:mah] synonym: "normal dGTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2017-09-04T14:43:29Z [Term] id: FYPO:0006206 name: decreased protein localization to chromatin during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during a cellular response to phosphate starvation." [PMID:19933844, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin during cellular response to phosphate starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin during cellular response to phosphate ion starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2017-09-04T14:44:37Z [Term] id: FYPO:0006207 name: decreased rate of actin filament depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament depolymerization, i.e. the removal of actin monomers from a filament, is decreased." [PMID:16866873, PomBase:mah] synonym: "decreased rate of actin filament depolymerisation" EXACT [PomBase:mah] synonym: "decreased rate of actin filament depolymerization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actin filament depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of actin filament depolymerization" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth created_by: midori creation_date: 2017-09-12T13:16:19Z [Term] id: FYPO:0006208 name: altered RNA level during cellular response to copper ion starvation def: "A cell phenotype in which the amount of RNA measured in a cell differs from normal during a cellular response to copper ion starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal RNA level during cellular response to copper ion starvation" EXACT [PomBase:mah] synonym: "altered cellular RNA level during cellular response to copper ion starvation" EXACT [PomBase:mah] synonym: "altered RNA level during cellular response to copper starvation" EXACT [PomBase:mah] synonym: "altered RNA level during copper starvation" EXACT [PomBase:mah] synonym: "altered transcript level during cellular response to copper ion starvation" EXACT [PomBase:vw] is_a: FYPO:0000824 ! altered RNA level created_by: midori creation_date: 2017-09-12T13:33:11Z [Term] id: FYPO:0006209 name: decreased RNA level during cellular response to copper ion starvation def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during cellular response to copper ion starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper starvation" EXACT [PomBase:mah] synonym: "decreased transcript level during cellular response to copper ion starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to copper ion starvation" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level is_a: FYPO:0006208 ! altered RNA level during cellular response to copper ion starvation created_by: midori creation_date: 2017-09-12T13:34:34Z [Term] id: FYPO:0006210 name: decreased RNA level during cellular response to copper ion starvation during spore germination def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal during spore germination. Total RNA or a specific RNA may be affected." [PMID:28572514, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to copper ion starvation during spore germination" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to copper ion starvation during spore germination" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper ion depletion during spore germination" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to copper ion deprivation during spore germination" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to copper ion starvation during spore germination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to copper starvation during spore germination" EXACT [PomBase:mah] synonym: "decreased RNA level during copper ion starvation during spore germination" EXACT [PomBase:al] synonym: "decreased transcript level during cellular response to copper ion starvation during spore germination" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to copper ion starvation during spore germination" EXACT [PomBase:mah] is_a: FYPO:0003280 ! decreased RNA level during cellular response to copper ion starvation during vegetative growth created_by: midori creation_date: 2017-09-12T13:38:47Z [Term] id: FYPO:0006211 name: inviable after spore germination, before germ tube formation def: "A phenotype in which a spore germinates but dies before forming a germ tube or dividing. Such spores exit dormancy and undergo isotropic swelling but the spore wall does not rupture and no germ tube emerges." [PMID:28572514, PomBase:mah] comment: Spores with this phenotype can be identified by loss of spore refractility that can be observed by light microscopy or by a decrease in optical absorbance of the spore suspension. synonym: "inviable following spore germination, before germ tube formation" EXACT [PomBase:mah] synonym: "inviable germinated spore, without germ tube formation" EXACT [PomBase:mah] synonym: "lethal after spore germination, before germ tube formation" EXACT [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2017-09-12T13:44:02Z [Term] id: FYPO:0006212 name: inviable after spore germination, before germ tube formation, during copper ion starvation def: "A phenotype in which a spore germinates but dies before forming a germ tube or dividing, when spore germination takes place under conditions of copper ion starvation. Such spores exit dormancy and undergo isotropic swelling but the spore wall does not rupture and no germ tube emerges." [PMID:28572514, PomBase:mah] comment: Spores with this phenotype can be identified by loss of spore refractility that can be observed by light microscopy or by a decrease in optical absorbance of the spore suspension. synonym: "inviable after spore germination, before germ tube formation, during cellular response to copper ion starvation" EXACT [PomBase:mah] synonym: "inviable after spore germination, before germ tube formation, during copper starvation" EXACT [PomBase:mah] synonym: "inviable following spore germination, before germ tube formation, during copper ion starvation" EXACT [PomBase:mah] synonym: "inviable germinated spore, without germ tube formation, during copper ion starvation" EXACT [PomBase:mah] synonym: "lethal after spore germination, before germ tube formation, during copper ion starvation" EXACT [PomBase:mah] is_a: FYPO:0006211 ! inviable after spore germination, before germ tube formation created_by: midori creation_date: 2017-09-12T13:50:59Z [Term] id: FYPO:0006213 name: normal septum morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the septum is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal septum morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septum morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2017-09-12T14:34:09Z [Term] id: FYPO:0006214 name: decreased spore germination frequency during copper ion starvation def: "A cell population phenotype in which the frequency of occurrence of spore germination is decreased when germination takes place under conditions of copper ion starvation." [PMID:28572514, PomBase:mah] comment: Note that this phenotype is usually assayed by observing a population of spores and observing how many germinate. Also consider annotating to 'inviable spore (FYPO:0002151)' with an extension to indicate incomplete penetrance, especially if you have a quantitative measurement. synonym: "decreased spore germination during copper ion starvation" EXACT [PomBase:mah] synonym: "decreased spore germination frequency during cellular response to copper ion starvation" EXACT [PomBase:mah] synonym: "decreased spore germination frequency during copper starvation" EXACT [PomBase:mah] synonym: "decreased spore viability during copper ion starvation" RELATED [PomBase:mah] synonym: "reduced spore germination frequency during copper ion starvation" EXACT [PomBase:mah] synonym: "reduced spore viability during copper ion starvation" RELATED [PomBase:mah] is_a: FYPO:0000581 ! decreased spore germination frequency created_by: midori creation_date: 2017-09-13T11:17:58Z [Term] id: FYPO:0006215 name: actin cables present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cables than normal." [PomBase:mah] synonym: "actin cables present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cables present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "actin cables present in reduced numbers" EXACT [PomBase:mah] synonym: "decreased level of actin cables" RELATED [PomBase:al] synonym: "fewer actin cables present" EXACT [PomBase:mah] synonym: "formin-nucleated actin cables present in decreased numbers" EXACT [GO:0070648, PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2017-09-13T16:03:29Z [Term] id: FYPO:0006216 name: normal establishment of actomyosin contractile ring localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which establishment of actomyosin contractile ring localization is normal (i.e. indistinguishable from wild type). Establishment of actomyosin contractile ring localization is the part of cytokinesis in which the actomyosin contractile ring is assembled in a specific location." [GO:1903486, PomBase:mah] synonym: "normal establishment of actomyosin contractile ring localisation" EXACT [PomBase:mah] synonym: "normal establishment of actomyosin contractile ring localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal establishment of actomyosin contractile ring localization during vegetative growth" EXACT [PomBase:mah] synonym: "normal establishment of actomyosin contractile ring positioning" EXACT [Pombase:vw] synonym: "normal establishment of cytokinetic contractile ring localization" EXACT [PomBase:vw] synonym: "normal establishment of mitotic actomyosin contractile ring localization" EXACT [GO:1903486, PomBase:mah] synonym: "normal establishment of mitotic contractile ring localization" EXACT [PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2017-09-18T12:59:18Z [Term] id: FYPO:0006217 name: increased protein localization to nucleolar periphery def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the border of the nuclear and nucleolar regions is increased." [PMID:16251348, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleolar periphery" EXACT [PomBase:mah] synonym: "increased protein localization to nucleolar periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleolar periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003687 ! abnormal protein localization to nucleolus created_by: midori creation_date: 2017-09-18T13:55:03Z [Term] id: FYPO:0006218 name: sensitive to potassium ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium ion starvation." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to potassium starvation in culture. synonym: "decreased growth during cellular response to potassium ion starvation" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to potassium ion starvation" EXACT [PomBase:mah] synonym: "hypersensitive to potassium ion starvation" EXACT [PomBase:mah] synonym: "reduced growth in low potassium" RELATED [PomBase:vw] synonym: "sensitive to potassium ion depletion" EXACT [PomBase:vw] synonym: "sensitive to potassium ion deprivation" EXACT [PomBase:vw] synonym: "sensitive to potassium ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to potassium ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to potassium starvation" EXACT [GO:0051365, PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2017-09-18T14:09:37Z [Term] id: FYPO:0006219 name: normal cell population growth during potassium ion starvation def: "A cell growth phenotype in which vegetative cell population growth is cell population growth is normal (i.e. indistinguishable from wild type) under conditions of potassium ion starvation." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to potassium starvation in culture. synonym: "normal cell population growth during potassium ion depletion" EXACT [PomBase:mah] synonym: "normal cell population growth during potassium ion deprivation" EXACT [PomBase:mah] synonym: "normal cell population growth during potassium starvation" EXACT [PomBase:mah] synonym: "normal cell population growth in response to potassium ion starvation" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth during potassium ion starvation" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2017-09-18T14:12:05Z [Term] id: FYPO:0006220 name: abolished protein localization to septum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to septum" EXACT [PomBase:mah] synonym: "abolished protein localization to septum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from septum" RELATED [PomBase:mah] synonym: "protein localization to septum abolished" EXACT [PomBase:mah] synonym: "protein localization to septum abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0002718 ! abnormal protein localization to septum created_by: midori creation_date: 2017-09-18T15:14:27Z [Term] id: FYPO:0006221 name: decreased protein localization to cell division site, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is decreased, and some of the protein is present in the cytoplasm instead." [PMID:26132084, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell division site, with protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "decreased protein localization to cell division site, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell division site, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein recruitment to cell division site, with protein mislocalized to cytoplasm" RELATED [PomBase:vw] synonym: "reduced protein localization to cell division site, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0002869 ! decreased protein localization to cell division site relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2017-09-18T15:22:35Z [Term] id: FYPO:0006222 name: decreased phosphatidylinositol phosphate level in plasma membrane def: "A cell phenotype in which the amount of one or more phosphatidylinositol phosphates measured in the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] comment: An increased level of a protein in the plasma membrane may result from increased protein transport to the membrane ('increased protein localization to plasma membrane FYPO:0002127), decreased endocytosis from the membrane ('abolished endocytosis' FYPO:0000421 or 'decreased endocytosis' FYPO:0000422), or both. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased phosphatidylinositol phosphate level in cell membrane during vegetative growth" EXACT [GO:0005886] synonym: "decreased phosphatidylinositol phosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phosphatidylinositol phosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "decreased plasma membrane phosphatidylinositol phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced phosphatidylinositol phosphate level in plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth is_a: FYPO:0005588 ! decreased cellular phosphoinositide level created_by: midori creation_date: 2017-09-19T14:26:18Z [Term] id: FYPO:0006223 name: abnormal ferrous iron import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferrous iron ions into a cell is abnormal." [PomBase:mah] synonym: "abnormal cellular ferrous iron import" EXACT [PomBase:al] synonym: "abnormal ferrous ion import" EXACT [PomBase:mah] synonym: "abnormal ferrous ion import across plasma membrane" EXACT [GO:0098711] synonym: "abnormal ferrous iron import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ferrous iron import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ferrous iron import into cell" EXACT [PomBase:mah] synonym: "abnormal ferrous iron ion import" EXACT [PomBase:mah] is_a: FYPO:0005973 ! abnormal transport during vegetative growth created_by: midori creation_date: 2017-09-19T14:33:18Z [Term] id: FYPO:0006224 name: decreased ferrous iron import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferrous iron ions into a cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cellular ferrous iron import" EXACT [PomBase:al] synonym: "decreased ferrous ion import" EXACT [PomBase:mah] synonym: "decreased ferrous ion import across plasma membrane" EXACT [GO:0098711] synonym: "decreased ferrous iron import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ferrous iron import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ferrous iron import into cell" NARROW [PomBase:mah] synonym: "decreased ferrous iron ion import" EXACT [PomBase:mah] synonym: "reduced ferrous iron import" EXACT [PomBase:mah] is_a: FYPO:0006223 ! abnormal ferrous iron import creation_date: 2017-09-19T14:33:25Z [Term] id: FYPO:0006225 name: sensitive to tetramethylammonium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tetramethylammonium. Cells stop growing (and may die) at a concentration of tetramethylammonium that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tetramethylammonium" EXACT [PomBase:mah] synonym: "sensitive to tetramethylammonium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tetramethylammonium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to TMA" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-09-19T14:47:39Z [Term] id: FYPO:0006226 name: sensitive to spermidine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to spermidine. Cells stop growing (and may die) at a concentration of spermidine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to spermidine" EXACT [PomBase:mah] synonym: "sensitive to spermidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to spermidine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-09-19T14:48:45Z [Term] id: FYPO:0006227 name: abnormal plasma membrane potential def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the plasma membrane potential, i.e. the electric potential existing across the plasma membrane, is abnormal." [PMID:16164595, PomBase:mah] synonym: "abnormal plasma membrane polarization" EXACT [PomBase:mah] synonym: "abnormal plasma membrane potential during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal plasma membrane potential during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth created_by: midori creation_date: 2017-09-19T14:53:35Z [Term] id: FYPO:0006228 name: increased plasma membrane potential def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the plasma membrane potential, i.e. the electric potential existing across the plasma membrane, is greater than normal." [PMID:16164595, PomBase:mah] synonym: "hyperpolarized plasma membrane" EXACT [PMID:16164595, PomBase:al] synonym: "increased plasma membrane polarization" EXACT [PomBase:mah] synonym: "increased plasma membrane potential during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased plasma membrane potential during vegetative growth" EXACT [PomBase:mah] synonym: "plasma membrane hyperpolarization" EXACT [PMID:16164595] is_a: FYPO:0006227 ! abnormal plasma membrane potential created_by: midori creation_date: 2017-09-19T14:55:14Z [Term] id: FYPO:0006229 name: increased duration of protein phosphorylation during cellular response to phosphate starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to phosphate starvation. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein phosphorylation during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein phosphorylation during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein phosphorylation during phosphate starvation" EXACT [PomBase:mah] synonym: "prolonged protein phosphorylation during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0000548 ! increased duration of protein modification during vegetative growth created_by: midori creation_date: 2017-09-19T15:02:41Z [Term] id: FYPO:0006230 name: decreased cytoplasmic translational initiation during cellular response to oxidative stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translational initiation in the cytoplasm is decreased during a cellular response to oxidative stress." [PMID:16278445, PomBase:mah] comment: Note that this term should be used only when an experiment measures the initiation of protein synthesis directly, e.g. by ribosome profiling. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "decreased cytoplasmic translation initiation during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during oxidative stress response" EXACT [PomBase:vw] synonym: "reduced cytoplasmic translational initiation during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0003125 ! decreased cytoplasmic translational initiation created_by: midori creation_date: 2017-10-10T15:28:24Z [Term] id: FYPO:0006231 name: decreased cytoplasmic translational initiation during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translational initiation in the cytoplasm is decreased during a cellular response to osmotic stress." [PMID:16278445, PomBase:mah] comment: Note that this term should be used only when an experiment measures the initiation of protein synthesis directly, e.g. by ribosome profiling. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "decreased cytoplasmic translation initiation during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytoplasmic translational initiation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cytoplasmic translational initiation during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0003125 ! decreased cytoplasmic translational initiation created_by: midori creation_date: 2017-10-10T15:29:34Z [Term] id: FYPO:0006232 name: abolished protein phosphorylation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2017-10-10T15:30:59Z [Term] id: FYPO:0006233 name: decreased protein localization to vacuolar membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to vacuolar membrane" EXACT [PomBase:mah] synonym: "decreased protein localization in vacuolar membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to vacuolar membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to vacuolar membrane during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to vacuole membrane" EXACT [PomBase:mah] synonym: "reduced protein localization to vacuolar membrane" EXACT [PomBase:mah] is_a: FYPO:0004249 ! abnormal protein localization to vacuolar membrane created_by: midori creation_date: 2017-10-10T15:34:25Z [Term] id: FYPO:0006234 name: increased cell population growth on gluconate carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing gluconate as the carbon source." [PomBase:al, PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on gluconate carbon source" BROAD [PomBase:mah] synonym: "increased vegetative cell growth on gluconate carbon source" EXACT [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2017-10-10T15:52:02Z [Term] id: FYPO:0006235 name: normal level of macromolecular complex def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of any macromolecular complex present in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of macromolecular complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of macromolecular complex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2017-10-10T15:54:17Z [Term] id: FYPO:0006236 name: normal cytosolic monomeric ribosome level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of monomeric ribosomes (80S monosomes) in the cytosol." [PMID:18065650, PomBase:mah] synonym: "cytosolic monomeric ribosomes present at normal level" EXACT [PomBase:mah] synonym: "normal cytosolic 80S monosome level" EXACT [PomBase:mah] synonym: "normal cytosolic monomeric 80S ribosome level" EXACT [PomBase:mah] synonym: "normal cytosolic monomeric ribosome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cytosolic monomeric ribosome level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cytosolic ribosome level" BROAD [PomBase:mah] synonym: "normal level of cytosolic monomeric ribosomes" EXACT [PomBase:al] is_a: FYPO:0006235 ! normal level of macromolecular complex created_by: midori creation_date: 2017-10-10T15:54:38Z [Term] id: FYPO:0006237 name: normal cytosolic half-mer polysome level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of half-mer polysomes in the cytosol. A half-mer polysome is a complex consisting of an mRNA bound to a single small ribosomal subunit, followed by one or more complete bound ribosomes." [PMID:18065650, PomBase:mah] synonym: "cytosolic half-mer polysomes present at normal level" EXACT [PomBase:mah] synonym: "normal cytosolic half-mer polysome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cytosolic half-mer polysome level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cytosolic halfmer polysome level" EXACT [PomBase:mah] synonym: "normal level of cytosolic half-mer polysomes" RELATED [PomBase:al] is_a: FYPO:0006235 ! normal level of macromolecular complex created_by: midori creation_date: 2017-10-10T15:54:43Z [Term] id: FYPO:0006238 name: decreased protein localization to centromere def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromere" EXACT [PomBase:mah] synonym: "decreased protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "reduced protein localization to centromere" EXACT [PomBase:mah] is_a: FYPO:0005597 ! abnormal protein localization to centromere created_by: midori creation_date: 2017-10-10T16:03:56Z [Term] id: FYPO:0006239 name: increased protein localization to centromere def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromere" EXACT [PomBase:mah] synonym: "increased protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0005597 ! abnormal protein localization to centromere created_by: midori creation_date: 2017-10-10T16:04:09Z [Term] id: FYPO:0006240 name: decreased rate of mitotic DNA replication elongation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is decreased during a cellular response to DNA damage." [PMID:28806726, PomBase:mah] synonym: "decreased rate of DNA replication elongation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of DNA strand elongation involved in mitotic DNA replication during cellular response to DNA damage" EXACT [PomBase:mah] synonym: "decreased rate of DNA strand elongation involved in nuclear cell cycle DNA replication during cellular response to DNA damage" EXACT [GO:1902319] synonym: "decreased rate of mitotic DNA replication elongation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of mitotic DNA replication elongation during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0003923 ! decreased rate of mitotic DNA replication elongation created_by: midori creation_date: 2017-10-11T16:16:07Z [Term] id: FYPO:0006241 name: abnormal negative regulation of mitotic DNA replication initiation during cellular response to DNA damage def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal during a cellular response to DNA damage. May result in re-replication of all or part of the genome." [PMID:28806726, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000216 ! abnormal negative regulation of mitotic DNA replication initiation created_by: midori creation_date: 2017-10-11T16:18:32Z [Term] id: FYPO:0006242 name: decreased replication fork stalling during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication forks stall at a lower frequency in mutant cells than in wild type during a cellular response to DNA damage." [PMID:28806726, PomBase:mah] comment: Use this term in cases where a DNA damaging agent causes increased replication fork stalling at a lower frequency in mutant cells than in wild type. synonym: "decreased frequency of replication fork stalling during cellular response to DNA damage" EXACT [PomBase:mah] synonym: "decreased replication fork stalling during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork stalling during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "reduced replication fork stalling during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2017-10-11T16:22:28Z [Term] id: FYPO:0006243 name: obsolete abnormal short range intra-arm mitotic chromosome condensation during interphase def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is abnormal over short (less than 90 kb) ranges within a chromosome arm." [PMID:28825727, PomBase:mah] comment: This term was made obsolete because it was added in error and does not describe an observed phenotype. synonym: "abnormal short range intra-arm chromosome condensation during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal short range intra-arm chromosome condensation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal short range intra-arm mitotic chromosome condensation during interphase during vegetative growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0006302 created_by: midori creation_date: 2017-10-17T13:38:34Z [Term] id: FYPO:0006244 name: obsolete abolished short range intra-arm mitotic chromosome condensation during interphase def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation does not occur over short (less than 90 kb) ranges within a chromosome arm." [PMID:28825727, PomBase:mah] comment: This term was made obsolete because it was added in error and does not describe an observed phenotype. is_obsolete: true consider: FYPO:0006302 created_by: midori creation_date: 2017-10-17T13:42:29Z [Term] id: FYPO:0006245 name: obsolete decreased medium range intra-arm mitotic chromosome condensation during interphase def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is decreased over medium (90-940 kb) ranges within a chromosome arm." [PMID:28825727, PomBase:mah] comment: This term was made obsolete because it was added in error and does not describe an observed phenotype. synonym: "decreased medium range intra-arm chromosome condensation during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased medium range intra-arm chromosome condensation during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased medium range intra-arm mitotic chromosome condensation during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced medium range intra-arm mitotic chromosome condensation during interphase" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0006302 created_by: midori creation_date: 2017-10-17T13:47:24Z [Term] id: FYPO:0006246 name: increased protein localization to nucleus during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to osmotic stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus during cellular response to osmotic stress during vegetative growth" EXACT [GO:0034504, PomBase:mah] synonym: "increased protein localization to nucleus during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to nucleus during osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001130 ! increased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2017-10-17T13:55:26Z [Term] id: FYPO:0006247 name: premature mitotic G2/M phase transition during cellular response to osmotic stress def: "A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins earlier than normal during a cellular response to osmotic stress. The duration of G2 phase is thus shorter than normal. The mitotic G2/M transition is the point at which a cell commits to entering M phase, and begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed." [GO:0000086, PomBase:mah] comment: Use this term if you have measured CDK activity or calculated the transition point to detect the transition; otherwise, consider using 'premature mitosis' (FYPO:0001046) or one of its descendants. A G2/M advance may indicate that a checkpoint, such as the DNA replication checkpoint or the G2/M DNA damage checkpoint, is impaired. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "advanced mitotic G2 phase progression during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "advanced mitotic G2/M transition during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "cell cycle, mitotic G2 advance during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "decreased duration of mitotic G2 phase during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "decreased duration of mitotic G2 phase during cellular response to osmotic stress during vegetative growth" RELATED [PomBase:mah] synonym: "decreased mitotic G2 duration during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "increased rate of mitotic G2 phase progression during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "mitotic cell cycle advance at G2/M transition during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "mitotic G2 advance during cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "mitotic G2/M transition advance during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "mitotic G2/M transition advance during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "premature cell cycle progression through mitotic G2/M phase transition during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "premature G2/M phase transition during cellular response to osmotic stress during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic G2/M phase transition during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic G2/M transition during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0002516 ! premature mitotic G2/M phase transition created_by: midori creation_date: 2017-10-17T14:13:09Z [Term] id: FYPO:0006248 name: increased centromere clustering at nuclear periphery during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is increased during mitosis. Normally, centromere-kinetochore complexes cluster near the old spindle pole body during interphase of the mitotic cell cycle, but are not as tightly clustered during mitosis." [PMID:28825727, PomBase:mah] synonym: "increased centromere clustering at nuclear periphery during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased centromere clustering at nuclear periphery during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased centromere clustering at old mitotic spindle pole body during mitosis" RELATED [PomBase:vw] synonym: "increased centromere clustering at SPB during mitosis" RELATED [PomBase:mah] synonym: "increased centromere clustering at spindle pole body during mitosis" RELATED [GO:0072766, PomBase:mah] synonym: "increased centromere-SPB clustering during mitosis" RELATED [GO:0072766] synonym: "increased inter-centromere connection during mitosis" EXACT [PomBase:vw] synonym: "increased kinetochore clustering at old mitotic spindle pole body during mitosis" RELATED [PomBase:vw] synonym: "increased kinetochore clustering at SPB during mitosis" RELATED [GO:0072766] synonym: "increased kinetochore clustering at spindle pole body during mitosis" RELATED [PomBase:mah] synonym: "increased kinetochore localization at spindle pole body during mitosis" RELATED [GO:0072766] synonym: "increased kinetochores to spindle pole body clustering during mitosis" RELATED [PomBase:vw] synonym: "increased mitotic centromere clustering at nuclear periphery during mitosis" EXACT [PomBase:vw] is_a: FYPO:0001779 ! abnormal centromere clustering at nuclear periphery during vegetative growth created_by: midori creation_date: 2017-10-17T16:06:21Z [Term] id: FYPO:0006249 name: normal tRNA aminoacylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA aminoacylation, the formation of an ester bond between a tRNA molecule and an amino acid specified by the tRNA anticodon, is normal (i.e. indistinguishable from wild type)." [GO:0006418, PomBase:mah] synonym: "normal tRNA aminoacylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA aminoacylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal tRNA aminoacylation for protein translation" EXACT [GO:0006418] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-10-18T14:10:14Z [Term] id: FYPO:0006250 name: abnormal tRNA aminoacylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA aminoacylation, the formation of an ester bond between a tRNA molecule and an amino acid specified by the tRNA anticodon, is abnormal. All tRNAs aminoacylation may be abnormal, or the aminoacylation of one or more specific tRNAs may be affected." [GO:0006418, PomBase:mah] synonym: "abnormal tRNA aminoacylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tRNA aminoacylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal tRNA aminoacylation for protein translation" EXACT [GO:0006418] synonym: "abnormal tRNA charging" NARROW [GO:0006418] is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth is_a: FYPO:0004851 ! abnormal RNA metabolic process created_by: midori creation_date: 2017-10-18T14:20:31Z [Term] id: FYPO:0006251 name: decreased tRNA aminoacylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA aminoacylation, the formation of an ester bond between a tRNA molecule and an amino acid specified by the tRNA anticodon, is decreased. All tRNAs aminoacylation may be decreased, or the aminoacylation of one or more specific tRNAs may be affected." [GO:0006418, PomBase:mah] synonym: "decreased tRNA aminoacylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tRNA aminoacylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tRNA aminoacylation for protein translation" EXACT [GO:0006418] synonym: "decreased tRNA charging" NARROW [GO:0006418] synonym: "reduced tRNA aminoacylation" EXACT [PomBase:mah] is_a: FYPO:0006250 ! abnormal tRNA aminoacylation created_by: midori creation_date: 2017-10-18T14:22:39Z [Term] id: FYPO:0006252 name: abnormal tRNA folding def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the folding of tRNAs into the correct tertiary structure is abnormal. All tRNA folding may be abnormal, or the aminoacylation of one or more specific tRNAs may be affected." [GO:0061818, PomBase:mah] synonym: "abnormal tRNA folding during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tRNA folding during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2017-10-18T14:27:34Z [Term] id: FYPO:0006253 name: normal tRNA binding def: "A molecular function phenotype in which an interaction between a protein and transfer RNA (tRNA) is normal (i.e. indistinguishable from wild type). One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "normal protein-transfer RNA interaction" EXACT [PomBase:mah] synonym: "normal protein-tRNA interaction" EXACT [PomBase:mah] synonym: "normal transfer RNA binding" EXACT [PomBase:mah] is_a: FYPO:0002357 ! normal protein-RNA interaction created_by: midori creation_date: 2017-10-18T14:53:22Z [Term] id: FYPO:0006254 name: abnormal ribosome footprint size distribution def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of ribosomal footprint lengths in a cell differs from wild type. Ribosomal footprints are RNA fragments protected by the ribosome, and normally range from 28-31 nucleotides long." [PMID:28945192, PomBase:mah] synonym: "abnormal ribosome footprint length distribution" EXACT [PomBase:mah] synonym: "abnormal ribosome footprint size distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ribosome footprint size distribution during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2017-10-23T13:58:48Z [Term] id: FYPO:0006255 name: increased level of short ribosome footprints during endoplasmic reticulum unfolded protein response def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of ribosomal footprint lengths in a cell includes more short footprints than wild type when the cell undergoes an endoplasmic reticulum unfolded protein response (UPR). Ribosomal footprints are RNA fragments protected by the ribosome, and normally range from 28-31 nucleotides long." [PMID:28945192, PomBase:mah] synonym: "increased level of short ribosome footprints during endoplasmic reticulum unfolded protein response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of short ribosome footprints during endoplasmic reticulum unfolded protein response during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of short ribosome footprints during ER unfolded protein response" EXACT [GO:0030968] synonym: "increased level of short ribosome footprints during erUPR" EXACT [GO:0030968] synonym: "increased level of short ribosome footprints upon UPR induction" EXACT [PomBase:vw] is_a: FYPO:0006254 ! abnormal ribosome footprint size distribution created_by: midori creation_date: 2017-10-23T14:14:08Z [Term] id: FYPO:0006256 name: normal mitotic cohesin unloading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin unloading is normal (i.e. indistinguishable from wild type). Cohesin unloading is the topological unlinking of a cohesin ring complex from chromatin, which negatively regulates sister chromatid cohesion." [GO:0061781, PomBase:mah] synonym: "normal cohesin unloading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal cohesin unloading during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2017-10-23T14:29:10Z [Term] id: FYPO:0006257 name: normal duration of mitotic prophase def: "A cell cycle phenotype in which the duration of prophase of mitosis normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of mitotic prophase during vegetative growth" EXACT [PomBase:mah] synonym: "normal duration of prophase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal duration of prophase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2017-10-23T14:31:42Z [Term] id: FYPO:0006258 name: normal rate of mitotic spindle elongation during prophase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is normal (i.e. indistinguishable from wild type) during prophase." [PMID:28455357, PomBase:mah] synonym: "normal mitotic spindle elongation rate during prophase" EXACT [PomBase:mah] synonym: "normal rate of mitotic spindle elongation during prophase during vegetative growth" EXACT [PomBase:mah] synonym: "normal rate of spindle elongation during mitotic prophase" EXACT [PomBase:mah] synonym: "normal rate of spindle elongation during prophase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0004429 ! normal rate of mitotic spindle elongation created_by: midori creation_date: 2017-10-23T14:32:55Z [Term] id: FYPO:0006259 name: normal mitotic spindle length during metaphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the length of the mitotic spindle is normal (i.e. indistinguishable from wild type) during metaphase." [PomBase:mah] synonym: "normal mitotic spindle length during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal spindle length during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal spindle length during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth relationship: part_of FYPO:0001399 ! normal mitotic spindle created_by: midori creation_date: 2017-10-23T14:34:51Z [Term] id: FYPO:0006260 name: abolished subtelomeric chromatin knob formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin knobs in subtelomeric regions does not occur. Chromatin knobs are highly condensed chromatin bodies formed from subtelomeric heterochromatin (observed on chromosomes 1 and 2)." [PMID:26804021, PomBase:mah] synonym: "abolished subtelomeric chromatin condensation" BROAD [PomBase:mah] synonym: "abolished subtelomeric chromatin knob assembly" EXACT [PomBase:mah] synonym: "knob-containing nuclei absent" RELATED [Pombase:al] synonym: "subtelomeric chromatin knob formation abolished" EXACT [PomBase:mah] is_a: FYPO:0004543 ! abnormal heterochromatin organization during vegetative growth created_by: midori creation_date: 2017-10-23T14:37:56Z [Term] id: FYPO:0006261 name: abolished histone H3-K36 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K36 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K36me3 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 trimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 trimethylation absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002919 ! abolished histone H3-K36 methylation during vegetative growth created_by: midori creation_date: 2017-10-23T14:39:59Z [Term] id: FYPO:0006262 name: inviable stubby binucleate vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is inviable and has two nuclei, and the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable stubby binucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable stubby binucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable watermelon-shaped binucleate vegetative cell" EXACT [PomBase:mah] synonym: "lethal; stubby binucleate vegetative cell" EXACT [PomBase:mah] synonym: "stubby binucleate inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001222 ! binucleate vegetative cell is_a: FYPO:0006199 ! inviable stubby multinucleate vegetative cell relationship: has_part FYPO:0001222 ! binucleate vegetative cell created_by: midori creation_date: 2017-10-23T15:50:41Z [Term] id: FYPO:0006263 name: increased histone H3-K36 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is increased." [PomBase:mah] synonym: "increased histone H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K36 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K36me3 during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002918 ! abnormal histone H3-K36 methylation during vegetative growth created_by: midori creation_date: 2017-10-25T16:07:35Z [Term] id: FYPO:0006264 name: decreased telomeric DNA separation during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation is decreased at the telomeric regions during anaphase B. The remainder of the sister chromatids may or may not separate normally." [PMID:21540296, PomBase:mah] synonym: "decreased DNA separation at telomere during anaphase B" EXACT [PomBase:mah] synonym: "decreased mitotic sister chromatid separation at telomere during anaphase B" EXACT [PomBase:mah] synonym: "decreased mitotic telomeric DNA separation during anaphase B" EXACT [PomBase:vw] synonym: "decreased segregation of telomeric DNA during anaphase B" RELATED [PomBase:mah] synonym: "decreased telomere disjunction during anaphase B" EXACT [PomBase:vw] synonym: "decreased telomere separation during anaphase B" EXACT [PomBase:mah] synonym: "decreased telomeric DNA separation during anaphase B during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased telomeric DNA separation during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "decreased telomeric DNA separation during anaphase B of mitosis" EXACT [PomBase:mah] synonym: "increased sister chromatid telomere nondisjunction at anaphase B" EXACT [PomBase:vw] synonym: "increased taz1 foci at anaphase B" RELATED [PomBase:vw] synonym: "reduced telomeric DNA separation during anaphase B" RELATED [PomBase:mah] is_a: FYPO:0005442 ! abnormal telomeric DNA separation created_by: midori creation_date: 2017-10-25T16:12:15Z [Term] id: FYPO:0006265 name: large vacuoles present following cellular hypotonic response def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are larger than normal after a cell has been subjected to hypotonic osmotic stress. Normally, vacuoles enlarge during hypotonic stress, and return to the original smaller size when the stress is relieved, either due to shrinking or fission." [PMID:28944093, PomBase:mah] synonym: "enlarged vacuoles present following cellular hypotonic response" EXACT [PomBase:mah] synonym: "large vacuoles large vacuoles present following cellular hypotonic response during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large vacuoles present during recovery from cellular hypotonic response" EXACT [PomBase:mah] synonym: "large vacuoles present following cellular hypotonic response during vegetative growth" EXACT [PomBase:mah] synonym: "large vacuoles present following hypotonic stress" EXACT [PomBase:mah] is_a: FYPO:0000123 ! large vacuoles during vegetative growth created_by: midori creation_date: 2017-10-30T13:22:41Z [Term] id: FYPO:0006266 name: normal vacuole size during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size of the fungal-type vacuole is normal (i.e. indistinguishable from wild type).." [PomBase:mah] synonym: "normal vacuolar size during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuole size during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2017-10-30T13:28:34Z [Term] id: FYPO:0006267 name: increased telomere clustering and tethering at nuclear periphery during mitotic metaphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering and tethering at the nuclear periphery is increased during mitotic metaphase." [GO:0120109, PMID:25778919, PomBase:mah] synonym: "decreased mitotic telomere dispersion during metaphase" EXACT [PomBase:vw] synonym: "increased telomere clustering and tethering at nuclear periphery during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased telomere clustering and tethering at nuclear periphery during mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased telomere clustering at nuclear periphery during mitotic metaphase" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0007418 ! abnormal telomere localization to nuclear periphery created_by: midori creation_date: 2017-10-30T13:35:39Z [Term] id: FYPO:0006268 name: increased histone H3-K9 dimethylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at protein coding gene during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me2 at protein coding gene during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at protein coding gene during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2017-10-30T13:51:19Z [Term] id: FYPO:0006269 name: decreased histone H3-K9 dimethylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at protein coding gene during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9me2 at protein coding gene during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at protein coding gene during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at protein coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2017-10-30T13:53:04Z [Term] id: FYPO:0006270 name: increased RNA level during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to phosphate starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to phosphate starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to phosphate depletion" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to phosphate deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during phosphate starvation" EXACT [PomBase:al] synonym: "increased transcript level during cellular response to phosphate starvation" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth is_a: FYPO:0003195 ! altered RNA level during cellular response to phosphate starvation created_by: midori creation_date: 2017-10-30T13:56:52Z [Term] id: FYPO:0006271 name: sensitive to floxuridine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to floxuridine (5-fluoro-2'-deoxyuridine). Cells stop growing (and may die) at a concentration of floxuridine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to floxuridine" EXACT [PomBase:mah] synonym: "sensitive to 5-fluoro-2'-deoxyuridine" EXACT [CHEBI:60761] synonym: "sensitive to 5-fluoro-2-deoxyuridine" EXACT [PomBase:mah] synonym: "sensitive to FdU" EXACT [PomBase:mah] synonym: "sensitive to floxuridin" EXACT [PomBase:mah] synonym: "sensitive to floxuridine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to floxuridine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to FUDR" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2017-10-30T14:12:23Z [Term] id: FYPO:0006272 name: premature mitotic DNA replication initiation from late origin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins earlier than normal at origins that normally fire late." [PMID:26804021, PomBase:mah] synonym: "advanced mitotic DNA replication initiation from late origin" EXACT [PomBase:mah] synonym: "premature DNA replication initiation from late origin during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature DNA replication initiation from late origin during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic DNA replication initiation at late origin" EXACT [PomBase:mah] synonym: "premature mitotic DNA replication initiation from late replication origin" EXACT [PomBase:mah] is_a: FYPO:0003498 ! premature mitotic DNA replication initiation relationship: output_of FYPO:0005758 ! abnormal regulation of mitotic DNA replication initiation from late origin created_by: midori creation_date: 2017-10-30T14:42:48Z [Term] id: FYPO:0006273 name: abnormal glycoprotein glycan structure in endoplasmic reticulum lumen def: "A phenotype in which the structure of the glycan moiety of a nascent glycoprotein in the endoplasmic reticulum lumen differs from wild type." [PMID:27587357, PomBase:mah] synonym: "abnormal glycoprotein glycan structure in ER lumen" EXACT [PomBase:mah] synonym: "abnormal glycoprotein oligosaccharide structure in endoplasmic reticulum lumen" RELATED [Pombase:vw] is_a: FYPO:0003290 ! abnormal glycoprotein glycan structure created_by: midori creation_date: 2017-10-30T16:01:44Z [Term] id: FYPO:0006274 name: abolished protein localization via NVT pathway def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the localization of soluble cytosolic proteins to the vacuole lumen via the NVT pathway does not occur." [PMID:26365378, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished localization of cytosolic proteins to the vacuole via the NVT pathway" EXACT [PomBase:vw] synonym: "abolished protein localization by the NVT pathway" EXACT [GO:0120113] synonym: "abolished protein localization from cytosol to vacuole via NVT pathway" EXACT [PomBase:mah] synonym: "abolished protein transport via NVT pathway" RELATED [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport during vegetative growth relationship: has_output FYPO:0006292 ! abolished protein localization to vacuole, with protein mislocalized to cytosol created_by: midori creation_date: 2017-10-30T16:04:44Z [Term] id: FYPO:0006275 name: increased pyknosis during stationary phase def: "A cellular process phenotype in which pyknosis, the form of chromatin condensation typical of cell death by apoptosis, occurs at a greater frequency than normal when the population in which the cell is found is in stationary phase." [GO:0030263, PMID:18653539, PomBase:mah] synonym: "increased apoptotic chromosome condensation during stationary phase" EXACT [GO:0030263] is_a: FYPO:0000629 ! abnormal apoptotic process created_by: midori creation_date: 2017-11-06T13:48:49Z [Term] id: FYPO:0006276 name: increased karyorrhexis during stationary phase def: "A cellular process phenotype in which karyorrhexis, the nuclear fragmentation typical of cell death by apoptosis, occurs at a greater frequency than normal when the population in which the cell is found is in stationary phase." [GO:0097194, PMID:18653539, PomBase:mah] synonym: "fragmented nuclear envelope during stationary phase entry" RELATED [PomBase:vw] synonym: "increased apoptotic nuclear fragmentation during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000629 ! abnormal apoptotic process created_by: midori creation_date: 2017-11-06T13:55:58Z [Term] id: FYPO:0006277 name: abnormal N-linked glycoprotein glycan structure def: "A phenotype in which the structure of an N-linked glycan moiety of a nascent or mature glycoprotein differs from wild type." [PMID:22988247, PomBase:mah] synonym: "abnormal N-linked glycoprotein oligosaccharide structure" RELATED [Pombase:vw] is_a: FYPO:0003290 ! abnormal glycoprotein glycan structure created_by: midori creation_date: 2017-11-07T15:54:21Z [Term] id: FYPO:0006278 name: abnormal O-linked glycoprotein glycan structure def: "A phenotype in which the structure of an O-linked glycan moiety of a nascent or mature glycoprotein differs from wild type." [PMID:22988247, PomBase:mah] synonym: "abnormal O-linked glycoprotein oligosaccharide structure" RELATED [Pombase:vw] is_a: FYPO:0003290 ! abnormal glycoprotein glycan structure created_by: midori creation_date: 2017-11-07T15:55:56Z [Term] id: FYPO:0006279 name: normal termination of RNA polymerase II transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II is normal (i.e. indistinguishable from wild type)." [GO:0006369, PomBase:mah] synonym: "normal RNA polymerase II transcription termination" EXACT [GO:0006369] synonym: "normal termination of RNA polymerase II transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal termination of RNA polymerase II transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0000859 ! normal metabolic process during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2017-11-15T14:05:06Z [Term] id: FYPO:0006280 name: increased mitotic recombination with crossover formation at centromere def: "A cellular process phenotype in which the occurrence of crossover formation as part of mitotic recombination is increased in centromeric regions." [PMID:28977643, PomBase:mah] is_a: FYPO:0000481 ! abnormal mitotic recombination created_by: midori creation_date: 2017-11-15T14:28:45Z [Term] id: FYPO:0006281 name: decreased mitotic recombination at centromere def: "A cellular process phenotype in which the occurrence of mitotic recombination is decreased in centromeric regions." [PMID:28977643, PomBase:mah] is_a: FYPO:0000482 ! decreased mitotic recombination created_by: midori creation_date: 2017-11-15T14:30:56Z [Term] id: FYPO:0006282 name: decreased mitotic recombination at chromosome arms def: "A cellular process phenotype in which the occurrence of mitotic recombination is decreased at chromosome arms." [PMID:28977643, PomBase:mah] is_a: FYPO:0000482 ! decreased mitotic recombination created_by: midori creation_date: 2017-11-15T14:32:00Z [Term] id: FYPO:0006283 name: abolished protein-proline dihydroxylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dihydroxylation of one or more proline residues in specific proteins, or at specific protein sites, does not occur." [PMID:29083304, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein-proline dihydroxylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein-proline dioxygenation during vegetative growth" EXACT [PomBase:al] synonym: "protein-proline dihydroxylation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification during vegetative growth created_by: midori creation_date: 2017-11-15T14:48:57Z [Term] id: FYPO:0006284 name: decreased protein-proline dihydroxylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dihydroxylation of one or more proline residues in specific proteins, or at specific protein sites, occurs to a lower extent than normal." [PMID:29083304, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein-proline dihydroxylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein-proline dioxygenation during vegetative growth" EXACT [PomBase:al] synonym: "reduced protein-proline dihydroxylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000545 ! decreased protein modification during vegetative growth created_by: midori creation_date: 2017-11-15T14:54:17Z [Term] id: FYPO:0006285 name: increased duration of protein localization to telomere during mitotic anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the telomere of a chromosome is longer than normal during anaphase B of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to telomere during mitotic anaphase B" EXACT [PomBase:mah] synonym: "increased duration of protein localization to chromosome, telomeric region during mitotic anaphase B" EXACT [GO:0070198, PomBase:mah] synonym: "increased duration of protein localization to telomere during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to telomere during anaphase B of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased duration of protein localization to telomeric region during mitotic anaphase B" EXACT [PomBase:vw] synonym: "prolonged protein localization to telomere during mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0005649 ! increased duration of protein localization to telomere created_by: midori creation_date: 2017-11-15T15:30:06Z [Term] id: FYPO:0006286 name: normal cyclin B1-CDK1 complex level def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of protein complexes consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1)." [PMID:7796804, PomBase:mah] synonym: "cyclin B1-CDK1 complexes present at normal level" EXACT [PomBase:mah] synonym: "normal cyclin B1-CDK1 complex level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cyclin B1-CDK1 complex level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006235 ! normal level of macromolecular complex created_by: midori creation_date: 2017-11-15T15:21:01Z [Term] id: FYPO:0006287 name: obsolete increased protein tyrosine phosphorylation during cellular response to hydroxyurea def: "OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to hydroxyurea." [PomBase:mah] comment: This term was made obsolete to implement a decision that protein modification terms should only include residue-specific information in cases where it is especially biologically significant, such as in histones or the RNA polymerase II CTD. In all other cases, phenotypic effects on specific modified residues should be captured in annotation extensions. synonym: "increased peptidyl-tyrosine phosphorylation during cellular response to hydroxyurea" EXACT [GO:0018108, PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to HU" EXACT [PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein tyrosine phosphorylation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "increased tyrosine phosphorylation during cellular response to hydroxyurea" EXACT [PomBase:al] is_obsolete: true replaced_by: FYPO:0002096 created_by: midori creation_date: 2017-11-15T15:49:16Z [Term] id: FYPO:0006288 name: decreased protein level during mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during mitotic G2 phase" RELATED [PomBase:mah] synonym: "decreased protein level during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein level during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during mitotic G2 phase" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2017-11-15T15:50:46Z [Term] id: FYPO:0006289 name: increased cellular phytoceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phytoceramide measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phytoceramide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phytoceramide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased phytoceramide accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2017-11-15T16:07:29Z [Term] id: FYPO:0006290 name: normal protein phosphorylation during mitotic S phase during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle and during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during cellular response to hydroxyurea during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during S phase during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002099 ! normal protein phosphorylation during cellular response to hydroxyurea created_by: midori creation_date: 2017-11-20T14:29:10Z [Term] id: FYPO:0006291 name: increased protein level during mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during mitotic G2 phase" RELATED [PomBase:mah] synonym: "increased protein level during G2 phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2017-11-20T14:32:40Z [Term] id: FYPO:0006292 name: abolished protein localization to vacuole, with protein mislocalized to cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which protein localization to the vacuole does not occur, and the protein is present in the cytoplasm instead." [PMID:26365378, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to vacuole, with protein mislocalised to cytosol" EXACT [PomBase:mah] synonym: "abolished protein localization to vacuole, with protein mislocalized to cytosol, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to vacuole, with protein mislocalized to cytosol, during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to vacuole abolished, with protein mislocalized to cytosol" EXACT [PomBase:mah] synonym: "protein mislocalized from vacuole to cytosol" RELATED [PomBase:vw] is_a: FYPO:0005490 ! abnormal protein localization to vacuole created_by: midori creation_date: 2017-12-08T13:46:28Z [Term] id: FYPO:0006293 name: normal protein localization via NVT pathway def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuole lumen via the NVT pathway is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation via NVT pathway" EXACT [PomBase:mah] synonym: "normal protein localization by the NVT pathway" EXACT [GO:0120113] synonym: "normal protein localization via NVT pathway during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization via NVT pathway during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein transport via NVT pathway" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2017-12-08T13:52:52Z [Term] id: FYPO:0006294 name: normal macroautophagy during nitrogen starvation def: "A cellular process phenotype in which macroautophagy is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm." [GO:0016236, PomBase:mah] synonym: "normal macroautophagy during cellular response to nitrogen starvation" EXACT [] synonym: "normal macroautophagy during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal macroautophagy during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype is_a: FYPO:0000385 ! normal macroautophagy created_by: midori creation_date: 2017-12-08T13:56:38Z [Term] id: FYPO:0006295 name: abolished macroautophagy during nitrogen starvation def: "A cellular process phenotype in which macroautophagy does not occur when the cell is subject to nitrogen starvation." [GO:0016236, PomBase:mah] synonym: "abolished macroautophagy during cellular response to nitrogen starvation" EXACT [] synonym: "abolished macroautophagy during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished macroautophagy during nitrogen deprivation" EXACT [PomBase:mah] synonym: "macroautophagy abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000380 ! abolished macroautophagy is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2017-12-08T13:58:57Z [Term] id: FYPO:0006296 name: increased negative regulation of transcription by glucose def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) occurs to a greater extent than normal. Specific genes that are normally not transcribed in the presence of glucose are not derepressed in the mutant under conditions that derepress transcription in wild type cells." [GO:0045014, PMID:20139237, PomBase:mah] synonym: "glucose repression defects" RELATED [PomBase:mah] synonym: "increased glucose repression" EXACT [GO:0045014, PomBase:mah] synonym: "increased glucose repression during vegetative growth" EXACT [PomBase:mah] synonym: "increased negative regulation of transcription by glucose during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased negative regulation of transcription by glucose during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription of glucose starvation gene during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000044 ! abnormal negative regulation of transcription by glucose created_by: midori creation_date: 2017-12-08T14:10:59Z [Term] id: FYPO:0006297 name: increased 5.8S rRNA length def: "A phenotype in which the processed 5.8S ribosomal RNA is longer than normal." [PMID:18438419, PomBase:mah] synonym: "increased 5.8S ribosomal RNA length" EXACT [PomBase:mah] synonym: "increased length of 5.8S rRNA" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2017-12-08T14:31:26Z [Term] id: FYPO:0006298 name: abnormal 5.8S rRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of the 5.8S ribosomal RNA molecule is abnormal." [GO:0000467, PomBase:mah] synonym: "abnormal 5.8S rRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal 5.8S rRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" EXACT [GO:0000467] is_a: FYPO:0007918 ! abnormal RNA 3'-end processing created_by: midori creation_date: 2017-12-08T14:36:13Z [Term] id: FYPO:0006299 name: increased chromatin silencing at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is increased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "increased chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "increased chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "increased chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "increased heterochromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] is_a: FYPO:0002346 ! abnormal chromatin silencing at centromere outer repeat is_a: FYPO:0005071 ! increased chromatin silencing at centromere created_by: midori creation_date: 2017-12-08T14:43:56Z [Term] id: FYPO:0006300 name: increased protein localization to heterochromatin at centromere inner repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere inner repeat regions is increased." [PMID:16797182, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at centromere inner repeat" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at centromere imr" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth is_a: FYPO:0004380 ! increased protein localization to pericentric heterochromatin during vegetative growth created_by: midori creation_date: 2017-12-08T14:54:51Z [Term] id: FYPO:0006301 name: abolished ribonuclease activity def: "A molecular function phenotype in which a ribonuclease activity is absent." [PomBase:mah] synonym: "ribonuclease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003821 ! abnormal ribonuclease activity created_by: midori creation_date: 2017-12-08T14:56:56Z [Term] id: FYPO:0006302 name: abolished intra-arm chromosome contact change during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which changes in contacts within a chromosome arm that normally take place during mitosis do not occur." [PMID:28825727, PomBase:mah] synonym: "abolished changes in intra-arm contacts in mitosis" EXACT [PomBase:vw] synonym: "abolished intra-arm chromosome contact change during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished intra-arm chromosome contact change during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "intra-arm chromosome contact change abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000214 ! abnormal mitotic chromosome condensation created_by: midori creation_date: 2017-12-11T13:50:17Z [Term] id: FYPO:0006303 name: decreased protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased, and some of the protein is present in the cytoplasm instead." [PMID:1903478, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actomyosin contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:al] synonym: "decreased protein localization to cytokinetic contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:vw] synonym: "decreased protein localization to mitotic contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:vw] synonym: "decreased protein recruitment to actomyosin contractile ring, with protein mislocalized to cytoplasm" RELATED [PomBase:vw] synonym: "reduced protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0002699 ! decreased protein localization to actomyosin contractile ring created_by: midori creation_date: 2017-12-11T14:05:55Z [Term] id: FYPO:0006304 name: medial F-actin spot present def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which F-actin forms a large spot in the medial region of the cell, instead of assembling into a contractile ring." [PMID:19713940, PMID:9635188, PomBase:mah] synonym: "actomyosin contractile ring absent, with medial F-actin spot present" EXACT [PomBase:mah] synonym: "medial F-actin spot present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "medial F-actin spot present during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001008 ! actomyosin contractile ring absent is_a: FYPO:0002398 ! abnormal actin cytoskeleton during vegetative growth relationship: has_part FYPO:0001008 ! actomyosin contractile ring absent created_by: midori creation_date: 2017-12-11T14:15:45Z [Term] id: FYPO:0006305 name: normal actin monomer binding def: "A molecular function phenotype in which the binding of a protein to one or more actin monomers is normal (i.e. indistinguishable from wild type). The relevant actin-binding protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal G-actin binding" EXACT [PomBase:mah] is_a: FYPO:0000703 ! normal protein-protein interaction created_by: midori creation_date: 2017-12-12T14:41:34Z [Term] id: FYPO:0006306 name: abnormal actin filament-based process def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which an actin filament-based process, i.e. any process that depends upon or alters the actin cytoskeleton, is abnormal." [GO:0030029, PomBase:mah] synonym: "abnormal actin filament-based process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actin filament-based process during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal microfilament-based process" RELATED [GO:0030029] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2017-12-12T14:44:34Z [Term] id: FYPO:0006307 name: decreased actin filament severing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament severing is decreased. Actin filament severing is the process in which an actin filament is broken down into smaller filaments." [GO:0051014, PMID:22024167, PomBase:mah] synonym: "decreased actin filament severing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased actin filament severing during vegetative growth" EXACT [PomBase:mah] synonym: "decreased F-actin severing" EXACT [GO:0051014] synonym: "reduced actin filament severing" EXACT [PomBase:mah] is_a: FYPO:0006306 ! abnormal actin filament-based process created_by: midori creation_date: 2017-12-12T14:44:43Z [Term] id: FYPO:0006308 name: thick actin cables in medial region def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are thicker than normal in the medial region of the cell." [PomBase:mah] comment: Cells with this phenotype usually have thick actin cables instead of a well-formed contractile ring near the midpoint of the cell, when the ring would normally form and contract during cytokinesis. synonym: "increased actin cable thickness in medial region" EXACT [PomBase:mah] synonym: "thick actin cables in medial region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "thick actin cables in medial region during vegetative growth" EXACT [PomBase:mah] synonym: "thick actin cables in medial region of cell" EXACT [PomBase:mah] synonym: "thick formin-nucleated actin cables in medial region" EXACT [PomBase:mah] is_a: FYPO:0002437 ! thick actin cables created_by: midori creation_date: 2017-12-12T14:49:31Z [Term] id: FYPO:0006309 name: increased nucleosome occupancy at FLEX element def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing FLEX elements. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:26804917, PomBase:mah] synonym: "increased nucleosome occupancy at FLEX element during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy at FLEX element during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003812 ! abnormal nucleosome positioning at stress response genes created_by: midori creation_date: 2017-12-15T15:16:34Z [Term] id: FYPO:0006310 name: abnormal DNA-3'-diphospho-5'-guanosine diphosphatase activity def: "A molecular function phenotype in which the observed rate of DNA-3'-diphospho-5'-guanosine diphosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2018-01-03T11:55:23Z [Term] id: FYPO:0006311 name: abolished DNA-3'-diphospho-5'-guanosine diphosphatase activity def: "A molecular function phenotype in which DNA-3'-diphospho-5'-guanosine diphosphatase activity is absent." [PomBase:mah] synonym: "DNA-3'-diphospho-5'-guanosine diphosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0006310 ! abnormal DNA-3'-diphospho-5'-guanosine diphosphatase activity created_by: midori creation_date: 2018-01-03T11:55:29Z [Term] id: FYPO:0006312 name: decreased DNA-3'-diphospho-5'-guanosine diphosphatase activity def: "A molecular function phenotype in which the observed rate of DNA-3'-diphospho-5'-guanosine diphosphatase activity is decreased." [PomBase:mah] synonym: "reduced DNA-3'-diphospho-5'-guanosine diphosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0006310 ! abnormal DNA-3'-diphospho-5'-guanosine diphosphatase activity created_by: midori creation_date: 2018-01-03T11:55:34Z [Term] id: FYPO:0006313 name: abolished meiotic G2/MI transition def: "A cell phenotype in which progression from meiotic G2 phase to M phase of meiosis I does not occur." [PMID:29259000, PomBase:mah] synonym: "abolished entry into meiosis" RELATED [PMID:29259000, PomBase:mah, PomBase:vw] synonym: "abolished G2/MI transition of meiotic cell cycle" EXACT [GO:0008315] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2018-01-05T11:19:57Z [Term] id: FYPO:0006314 name: abolished ascus formation def: "A cell phenotype in which formation of the ascus, the sac-like structure that encloses spores, does not occur." [PMID:29259000, PomBase:mah] synonym: "abolished asci formation" EXACT [PMID:29259000, PomBase:vw] synonym: "abolished ascus development" RELATED [GO:0008315] is_a: FYPO:0000680 ! abnormal ascus development created_by: midori creation_date: 2018-01-05T11:27:01Z [Term] id: FYPO:0006315 name: abolished homologous chromosome segregation def: "A cellular process phenotype in which homologous chromosome segregation does not occur. Homologous chromosome segregation is the process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle." [GO:0045143, PMID:29259000, PomBase:mah] synonym: "abolished chromosome segregation during meiosis I" EXACT [PomBase:mah] synonym: "homologous chromosome segregation abolished" EXACT [PomBase:mah] is_a: FYPO:0004159 ! abnormal homologous chromosome segregation created_by: midori creation_date: 2018-01-05T11:30:51Z [Term] id: FYPO:0006316 name: spindle pole bodies present in increased numbers during meiosis II def: "A physical cellular phenotype in which cells contain more spindle pole bodies (SPBs) than normal during the second meiotic nuclear division." [PMID:29259000, PomBase:mah] synonym: "excess meiotic spindle pole bodies present during meiosis II" EXACT [PomBase:mah] synonym: "excess spindle pole bodies present during meiosis II" EXACT [PomBase:mah] synonym: "extra spindle pole bodies present during meiosis II" EXACT [PomBase:mah] synonym: "SPBs present in increased numbers during meiosis II" EXACT [PomBase:mah] synonym: "spindle pole bodies present in greater numbers during meiosis II" EXACT [PomBase:mah] synonym: "spindle pole bodies present in increased numbers during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004609 ! spindle pole bodies present in increased numbers during meiosis created_by: midori creation_date: 2018-01-05T11:33:22Z [Term] id: FYPO:0006317 name: decreased protein localization to meiotic spindle pole body during meiosis II def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during the second meiotic nuclear division." [PMID:29259000, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Use this term for cells in which in which the re-accumulation of some spindle pole body components does not occur at the onset of meiosis I. synonym: "decreased protein localisation to meiotic spindle pole body during meiosis II" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic SPB during meiosis II" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic spindle pole body during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during meiosis II" EXACT [PomBase:mah] synonym: "reduced protein localization to meiotic spindle pole body during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0002772 ! decreased protein localization to meiotic spindle pole body created_by: midori creation_date: 2018-01-05T11:35:19Z [Term] id: FYPO:0006318 name: decreased DNA resection during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the extent of DNA resection upstream of a stalled replication fork is lower than normal. DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA." [PMID:29215009, PomBase:mah] synonym: "decreased DNA resection during replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased DNA resection during replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "decreased DNA resectioning during replication fork processing" EXACT [PomBase:amc] synonym: "decreased extent of DNA resection during replication fork processing" EXACT [PomBase:mah] synonym: "decreased extent of exonucleolytic DNA cleavage during replication fork processing" EXACT [PomBase:mah] synonym: "reduced DNA resection during replication fork processing" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2018-01-05T11:38:30Z [Term] id: FYPO:0006319 name: normal extent of DNA resection during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the extent of DNA resection upstream of a stalled replication fork is normal (i.e. indistinguishable from wild type). DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA." [PMID:29215009, PomBase:mah] synonym: "normal DNA resectioning during replication fork processing" RELATED [PomBase:mah] synonym: "normal extent of DNA resection during replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal extent of DNA resection during replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "normal extent of exonucleolytic DNA cleavage during replication fork processing" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2018-01-05T11:40:37Z [Term] id: FYPO:0006320 name: normal replication slippage during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications (\"replication slippage\") that normally results from processing arrested replication forks is normal (i.e. indistinguishable from wild type)." [PMID:29215009, PomBase:mah] synonym: "normal replication slippage during replication fork processing during vegetative growth" RELATED [PomBase:mah] synonym: "normal replication slippage during replication fork processing during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2018-01-05T11:44:15Z [Term] id: FYPO:0006321 name: decreased protein localization to chromatin at stalled replication fork def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is decreased." [PMID:29215009, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at stalled replication fork during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at stalled replication fork during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to chromatin at stalled replication fork during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-01-05T11:50:11Z [Term] id: FYPO:0006322 name: increased protein localization to chromatin at stalled replication fork def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is increased." [PMID:29215009, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at stalled replication fork during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at stalled replication fork during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-01-05T11:50:52Z [Term] id: FYPO:0006323 name: loss of viability following replication fork stalling def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after stalled replication forks accumulate." [PMID:29215009, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under conditions that cause replication fork stalling, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth (without fork stalling) is measured and compared to wild type. synonym: "decreased viability following replication fork stalling" EXACT [PomBase:mah] synonym: "loss of cell population viability following replication fork stalling" EXACT [PomBase:mah] synonym: "reduced viability following replication fork stalling" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2018-01-05T11:52:54Z [Term] id: FYPO:0006324 name: normal septin ring morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the septin ring is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal medial cortex septin ring morphology" EXACT [GO:0036391] synonym: "normal septin ring morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septin ring morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2018-01-05T13:16:35Z [Term] id: FYPO:0006325 name: elongated multinucleate vegetative cell with multinucleate compartment def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, may contain a septum, and contains multiple nuclei (usually four or more) per compartment." [PMID:18272786, PomBase:mah] synonym: "elongated multinucleate vegetative cell with multinucleate compartment during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated multinucleate vegetative cell with multinucleate compartment during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate vegetative cell with tetranucleate compartment" NARROW [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell created_by: midori creation_date: 2018-01-05T13:18:12Z [Term] id: FYPO:0006326 name: decreased protein localization to medial cortical node def: "A cell phenotype in which the localization of a protein to the medial cortical nodes is decreased in the vegetative growth phase of the life cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "decreased protein localization to cytokinetic nodes" RELATED [PomBase:mah] synonym: "decreased protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein recruitment to medial cortical node" RELATED [PomBase:vw] synonym: "reduced protein localization to medial cortical node" EXACT [PomBase:mah] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node created_by: midori creation_date: 2018-01-10T15:52:02Z [Term] id: FYPO:0006327 name: abnormal rate of protein exchange in medial cortical node def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the medial cortical nodes is abnormal. Normally, myosin and other node proteins are turned over between the nodes and elsewhere at rates consistent for each protein." [PMID:21422229, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal rate of protein exchange in medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal rate of protein exchange in medial cortical node during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly created_by: midori creation_date: 2018-01-10T16:04:00Z [Term] id: FYPO:0006328 name: decreased protein level in spliceosomal complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in any spliceosomal complex is lower than normal." [PMID:28947618, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the proteasome is decreased, altering the proteasome stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level in spliceosomal complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level in spliceosomal complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in spliceosome" BROAD [GO:0005681] synonym: "decreased spliceosomal complex protein level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level in spliceosomal complex" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0005003 ! abnormal protein complex composition created_by: midori creation_date: 2018-01-10T16:13:53Z [Term] id: FYPO:0006329 name: abnormal organelle localization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which organelle localization, i.e. any process in which an organelle is transported to, and/or maintained in, a specific location, is abnormal." [GO:0051640, PomBase:mah] synonym: "abnormal organelle localisation" EXACT [PomBase:mah] synonym: "abnormal organelle localization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal organelle localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2018-01-23T13:13:16Z [Term] id: FYPO:0006330 name: decreased endoplasmic reticulum-plasma membrane tethering def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers occurs to a lower extent than normal." [GO:0061817, PomBase:mah] synonym: "abnormal ER-PM contact formation" RELATED [PomBase:vw] synonym: "decreased endoplasmic reticulum-plasma membrane tethering during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased endoplasmic reticulum-plasma membrane tethering during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ER-plasma membrane tethering" EXACT [GO:0061817] synonym: "decreased ER-PM tethering" EXACT [PomBase:mah] synonym: "increased ER-PM contact removal" RELATED [PomBase:vw] synonym: "increased ER-PM uncoupling" RELATED [PomBase:vw] synonym: "reduced endoplasmic reticulum-plasma membrane tethering" EXACT [PomBase:mah] is_a: FYPO:0006329 ! abnormal organelle localization created_by: midori creation_date: 2018-01-23T13:15:46Z [Term] id: FYPO:0006331 name: decreased mating efficiency during stationary phase def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal when the population in which the mating cells are found is in stationary phase." [PMID:25204792, PMID:28160081, PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). synonym: "reduced mating efficiency during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000708 ! decreased mating efficiency created_by: midori creation_date: 2018-01-23T14:00:34Z [Term] id: FYPO:0006332 name: normal mating efficiency during stationary phase def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is normal (i.e. the same as in wild-type cells) when the population in which the mating cells are found is in stationary phase." [PMID:25204792, PMID:28160081, PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). is_a: FYPO:0001147 ! normal mating efficiency created_by: midori creation_date: 2018-01-23T14:02:18Z [Term] id: FYPO:0006333 name: decreased zinc ion binding def: "A molecular function phenotype in which occurrence of zinc ion binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds zinc less than wild type, or that a mutation in one gene decreases zinc binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "decreased zinc binding" EXACT [PomBase:mah] synonym: "reduced zinc ion binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2018-01-23T14:03:57Z [Term] id: FYPO:0006334 name: decreased RNA level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to zinc ion starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to zinc ion limitation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to zinc ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "decreased RNA level in response to zinc ion starvation" EXACT [PomBase:vw] synonym: "decreased transcript level during cellular response to zinc ion starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to zinc ion starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2018-01-23T14:08:47Z [Term] id: FYPO:0006335 name: decreased microtubule nucleation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) occurs to a lesser extent than normal." [GO:0051418, PomBase:mah] synonym: "decreased microtubule nucleation by microtubule organizing center during vegetative growth" EXACT [GO:0051418] synonym: "decreased microtubule nucleation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced microtubule nucleation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005692 ! abnormal microtubule nucleation during vegetative growth created_by: midori creation_date: 2018-01-23T14:49:01Z [Term] id: FYPO:0006336 name: decreased mitotic microtubule nucleation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) occurs to a lesser extent than normal during mitosis." [GO:0051418, PMID:8834801, PomBase:mah] synonym: "decreased microtubule nucleation by microtubule organizing center during mitosis" EXACT [GO:0051418] synonym: "decreased microtubule nucleation during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased microtubule nucleation during mitosis" EXACT [PomBase:mah] synonym: "decreased mitotic microtubule nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitotic microtubule nucleation" EXACT [PomBase:mah] is_a: FYPO:0006335 ! decreased microtubule nucleation during vegetative growth created_by: midori creation_date: 2018-01-23T14:59:22Z [Term] id: FYPO:0006337 name: decreased interphase microtubule nucleation from spindle pole body def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the spindle pole body (SPB) occurs to a lesser extent than normal during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the SPB." [PMID:8834801, PomBase:mah] synonym: "decreased cytoplasmic microtubule nucleation from spindle pole body during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased interphase microtubule nucleation by spindle pole body" EXACT [GO:0051417] synonym: "decreased interphase microtubule nucleation from SPB" EXACT [PomBase:mah] synonym: "decreased interphase microtubule nucleation from spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule nucleation from spindle pole body during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced interphase microtubule nucleation from spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0005694 ! decreased interphase microtubule nucleation created_by: midori creation_date: 2018-01-23T15:01:06Z [Term] id: FYPO:0006338 name: nucleus mislocalized towards cell tip during mitotic telophase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the divided nuclei are located near the cell tips (instead of at the midpoint of the long axis of each daughter cell) during telophase of the mitotic cell cycle." [PMID:15937127, PomBase:mah] synonym: "nuclear displacement towards cell tip during mitotic telophase" EXACT [PomBase:vw] synonym: "nucleus displaced towards cell tip during mitotic telophase" EXACT [PomBase:vw] synonym: "nucleus mislocalised to cell tip during mitotic telophase" EXACT [PomBase:mah] synonym: "nucleus mislocalized towards cell end during mitotic telophase" EXACT [PomBase:mah] synonym: "nucleus mislocalized towards cell tip during mitotic telophase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nucleus mislocalized towards cell tip during mitotic telophase during vegetative growth" EXACT [PomBase:mah] synonym: "telophase nucleus mislocalized to cell tip" EXACT [PomBase:vw] is_a: FYPO:0009105 ! mislocalized nucleus during mitotic telophase created_by: midori creation_date: 2018-01-23T15:05:46Z [Term] id: FYPO:0006339 name: mononucleate vegetative cell with mislocalized nucleus def: "A cell phenotype in which a cell has one nucleus that is not in the normal location." [PMID:15937127, PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "lethal; mononucleate vegetative cell with mislocalized nucleus" EXACT [PomBase:mah] synonym: "mononucleate cell with abnormal nucleus location" EXACT [PomBase:mah] synonym: "mononucleate cell with abnormal nucleus position" EXACT [PomBase:mah] synonym: "mononucleate cell with asymmetrically localized nucleus" EXACT [PomBase:vw] synonym: "mononucleate cell with displaced nucleus" EXACT [PomBase:mah] synonym: "mononucleate cell with mislocalised nucleus" EXACT [PomBase:mah] synonym: "mononucleate cell with mislocalized nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "mononucleate cell with misplaced nucleus" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with mislocalized nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "vegetative cell with mislocalized mononucleus" EXACT [PomBase:vw] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0002069 ! mislocalized nucleus relationship: has_part FYPO:0000060 ! mononucleate vegetative cell relationship: has_part FYPO:0002069 ! mislocalized nucleus created_by: midori creation_date: 2018-01-23T15:13:12Z [Term] id: FYPO:0006340 name: endocytosis restricted to old cell end def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis occurs only at the old end of the cell during interphase of the mitotic cell cycle. Normally, endocytosis takes place at the old cell end throughout interphase, and also at the new end after NETO." [PMID:16141239, PomBase:mah] synonym: "endocytosis abolished at new cell end" EXACT [PomBase:mah] synonym: "endocytosis restricted to old cell end during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "endocytosis restricted to old cell end during mitotic interphase" EXACT [PomBase:mah] synonym: "endocytosis restricted to old cell end during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis restricted to old cell tip" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth created_by: midori creation_date: 2018-01-23T15:30:42Z [Term] id: FYPO:0006341 name: abolished equatorial endocytosis during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis does not occur in the equatorial region of the cell during mitosis as in wild-type cells." [PMID:16141239, PomBase:mah] synonym: "abolished endocytosis to cell division site" RELATED [PomBase:vw] synonym: "abolished equatorial endocytosis during cell division" RELATED [PomBase:mah] synonym: "abolished equatorial endocytosis during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished equatorial endocytosis during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished equatorial endocytosis during mitotic M phase" RELATED [PomBase:mah] synonym: "endocytosis restricted to cell end during mitosis" RELATED [PomBase:vw] synonym: "equatorial endocytosis abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis during vegetative growth created_by: midori creation_date: 2018-01-23T15:32:38Z [Term] id: FYPO:0006342 name: decreased microtubule binding def: "A molecular function phenotype in which the binding of a protein to one or more microtubules occurs to a lower extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "reduced microtubule binding" EXACT [PomBase:mah] is_a: FYPO:0001943 ! abnormal microtubule binding created_by: midori creation_date: 2018-01-26T11:11:38Z [Term] id: FYPO:0006343 name: abolished microtubule bundle formation def: "A cellular process phenotype in which microtubule bundle formation, which normally results in a parallel arrangement of microtubules, does not occur." [GO:0001578, PomBase:mah] synonym: "abolished microtubule array formation" RELATED [PomBase:vw] synonym: "abolished microtubule bundling" EXACT [GO:0001578] synonym: "microtubule bundle formation abolished" EXACT [PomBase:mah] is_a: FYPO:0002761 ! abnormal microtubule bundle formation created_by: midori creation_date: 2018-01-26T11:19:54Z [Term] id: FYPO:0006344 name: protein mislocalized to plasma membrane during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the plasma membrane is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the medial cortex in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to plasma membrane during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalised to plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2018-01-26T11:41:52Z [Term] id: FYPO:0006345 name: increased duration of protein phosphorylation during nitrogen starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal the cell is subject to nitrogen starvation. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein phosphorylation during cellular response to nitrogen starvation" EXACT [PomBase:mah] synonym: "prolonged protein phosphorylation during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0005033 ! abnormal protein phosphorylation during nitrogen starvation created_by: midori creation_date: 2018-01-26T11:49:06Z [Term] id: FYPO:0006346 name: bipolar mitotic spindle with decreased, irregular thickness def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle has two poles and can elongate during anaphase, but has decreased and non-uniform thickness along its length." [PMID:12951601, PomBase:mah] comment: In images of thin spindles, polar microtubules may appear not to reach continuously from pole to pole. synonym: "bipolar mitotic spindle with decreased, irregular thickness during mitotic cell cycle" EXACT [PomBase:mah] synonym: "bipolar mitotic spindle with decreased, irregular thickness during vegetative growth" EXACT [PomBase:mah] synonym: "decreased, irregular bipolar mitotic spindle thickness" EXACT [PomBase:mah] synonym: "thin, discontinuous bipolar mitotic spindle" RELATED [PomBase:mah] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle created_by: midori creation_date: 2018-01-26T11:59:01Z [Term] id: FYPO:0006347 name: sensitive to mechlorethamine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mechlorethamine. Cells stop growing (and may die) at a concentration of mechlorethamine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mechlorethamine" EXACT [PomBase:mah] synonym: "sensitive to 2-chloro-N-(2-chloroethyl)-N-methylethanamine" EXACT [CHEBI:28925] synonym: "sensitive to bis(2-chloroethyl)methylamine" EXACT [CHEBI:28925] synonym: "sensitive to HN2" EXACT [PMID:24192486] synonym: "sensitive to mechlorethamine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to mechlorethamine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2018-01-29T15:23:41Z [Term] id: FYPO:0006348 name: normal growth on mechlorethamine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mechlorethamine." [PomBase:mah] synonym: "normal cell population growth in presence of mechlorethamine" EXACT [PomBase:mah] synonym: "normal cell population growth on mechlorethamine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal growth on 2-chloro-N-(2-chloroethyl)-N-methylethanamine" EXACT [CHEBI:28925] synonym: "normal growth on bis(2-chloroethyl)methylamine" EXACT [CHEBI:28925] synonym: "normal growth on HN2" EXACT [PMID:124192486] synonym: "normal vegetative cell population growth on mechlorethamine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2018-01-29T15:26:43Z [Term] id: FYPO:0006349 name: abolished protein localization to chromatin at promoter def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at promoter element" EXACT [PomBase:mah, SO:0001659] synonym: "protein localization to chromatin at promoter abolished" EXACT [PomBase:mah] is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-01-31T13:36:31Z [Term] id: FYPO:0006351 name: mitotic spindle microtubules detached from spindle pole body def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubules become disconnected from the spindle pole body." [PMID:17579515, PomBase:mah] synonym: "mitotic spindle microtubules detached from SPB" EXACT [PomBase:mah] synonym: "mitotic spindle microtubules detached from spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "spindle microtubules detached from spindle pole body during mitosis" EXACT [PomBase:mah] synonym: "spindle microtubules detached from spindle pole body during mitotic cell cycle" EXACT [PomBase:mah] synonym: "spindle pole body detached from mitotic spindle microtubules" EXACT [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle is_a: FYPO:0001474 ! abnormal mitotic spindle pole body morphology is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2018-02-06T11:29:33Z [Term] id: FYPO:0006352 name: normal F-actin level in actomyosin contractile ring during early mitosis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type) during early mitosis (before anaphase)." [PMID:29343550, PomBase:mah] synonym: "normal abundance of actin in actomyosin contractile ring in early mitosis" EXACT [PomBase:vw] synonym: "normal actomyosin contractile ring F-actin level during early mitosis" EXACT [PomBase:mah] synonym: "normal F-actin level in actomyosin contractile ring during early mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal F-actin level in actomyosin contractile ring during early mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "normal F-actin level in contractile ring during early mitosis" EXACT [PomBase:al] synonym: "normal F-actin level in cytokinetic contractile ring during early mitosis" EXACT [PomBase:vw] synonym: "normal filamentous actin level in actomyosin contractile ring during early mitosis" EXACT [PomBase:mah] is_a: FYPO:0004740 ! normal actomyosin contractile ring created_by: midori creation_date: 2018-02-06T11:41:29Z [Term] id: FYPO:0006353 name: increased centromere central core transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere central core are present at greater levels than normal. Normally, the central core is not transcribed." [PMID:23267073, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "accumulation of centromere central core-derived RNA transcripts" RELATED [PomBase:vw] synonym: "increased centromere central core RNA level" EXACT [PomBase:al] synonym: "increased centromere central core-derived RNA accumulation" RELATED [PomBase:mah] synonym: "increased centromere central core-derived RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased centromere central core-derived RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased centromere central core-derived RNA transcript level" EXACT [PomBase:vw] synonym: "increased centromeric core transcript level" EXACT [PomBase:mah] is_a: FYPO:0004982 ! increased centromeric transcript level created_by: midori creation_date: 2018-02-06T12:14:14Z [Term] id: FYPO:0006354 name: abnormal transcription during glucose starvation def: "A cellular process phenotype in which transcription is abnormal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abnormal transcription during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "abnormal transcription during glucose depletion" EXACT [PomBase:vw] synonym: "abnormal transcription during glucose deprivation" EXACT [PomBase:vw] synonym: "abnormal transcription during glucose limitation" RELATED [PomBase:mah] synonym: "abnormal transcription in response to glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0005502 ! abnormal transcription created_by: midori creation_date: 2018-02-06T13:14:29Z [Term] id: FYPO:0006355 name: delayed onset of transcription during glucose starvation def: "A cellular process phenotype in which transcription begins later than normal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "delayed onset of transcription during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "delayed onset of transcription during glucose depletion" EXACT [PomBase:vw] synonym: "delayed onset of transcription during glucose deprivation" EXACT [PomBase:vw] synonym: "delayed onset of transcription during glucose limitation" RELATED [PomBase:mah] synonym: "delayed onset of transcription in response to glucose starvation" EXACT [PomBase:vw] synonym: "delayed transcription during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0006354 ! abnormal transcription during glucose starvation created_by: midori creation_date: 2018-02-06T13:15:30Z [Term] id: FYPO:0006356 name: abnormal chromatin remodeling def: "A cellular process phenotype in which chromatin remodeling, i.e. any dynamic structural change to chromatin, is abnormal." [GO:0006338, PomBase:mah] synonym: "abnormal chromatin modeling" EXACT [GO:0006338] synonym: "abnormal chromatin remodelling" EXACT [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2018-02-06T13:49:37Z [Term] id: FYPO:0006357 name: decreased chromatin remodeling during glucose starvation def: "A cellular process phenotype in which chromatin remodeling, i.e. any dynamic structural change to chromatin, occurs to a lower extent than normal when the cell is subject to glucose starvation." [GO:0006338, PMID:28674280, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased chromatin modeling during glucose starvation" EXACT [GO:0006338] synonym: "decreased chromatin remodeling during glucose depletion" EXACT [PomBase:mah] synonym: "decreased chromatin remodeling during glucose deprivation" RELATED [PomBase:mah] synonym: "decreased chromatin remodeling during glucose limitation" RELATED [PomBase:mah] synonym: "decreased chromatin remodelling during glucose starvation" EXACT [PomBase:mah] synonym: "reduced decreased chromatin remodeling during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0006356 ! abnormal chromatin remodeling created_by: midori creation_date: 2018-02-06T13:56:39Z [Term] id: FYPO:0006358 name: abolished chromatin remodeling during glucose starvation def: "A cellular process phenotype in which chromatin remodeling, i.e. any dynamic structural change to chromatin, does not occur when the cell is subject to glucose starvation." [GO:0006338, PMID:28674280, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abolished chromatin modeling during glucose starvation" EXACT [GO:0006338] synonym: "abolished chromatin remodeling during glucose depletion" EXACT [PomBase:mah] synonym: "abolished chromatin remodeling during glucose deprivation" RELATED [PomBase:mah] synonym: "abolished chromatin remodeling during glucose limitation" RELATED [PomBase:mah] synonym: "abolished chromatin remodelling during glucose starvation" EXACT [PomBase:mah] synonym: "chromatin remodeling during glucose starvation abolished" EXACT [PomBase:mah] is_a: FYPO:0006356 ! abnormal chromatin remodeling created_by: midori creation_date: 2018-02-06T13:59:56Z [Term] id: FYPO:0006359 name: decreased protein exchange at pericentric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of a protein in cis and trans between heterochromatin domains occurs to a lower extent than normal in regions of pericentric heterochromatin." [GO:0005721, PMID:26438724, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein exchange at centromeric heterochromatin" EXACT [GO:0005721] synonym: "decreased protein exchange at pericentric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein exchange at pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein motility on centromeric heterochromatin" EXACT [PomBase:al] synonym: "reduced protein exchange at pericentric heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2018-02-06T14:08:16Z [Term] id: FYPO:0006360 name: increased protein exchange at pericentric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of a protein in cis and trans between heterochromatin domains occurs to a greater extent than normal in regions of pericentric heterochromatin." [GO:0005721, PMID:26438724, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein exchange at centromeric heterochromatin" EXACT [GO:0005721] synonym: "increased protein exchange at pericentric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein exchange at pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein motility on centromeric heterochromatin" EXACT [PomBase:al] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2018-02-06T14:22:03Z [Term] id: FYPO:0006361 name: increased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a greater extent than normal." [PMID:26438724, PMID:29214404, PomBase:mah] synonym: "increased histone H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at subtelomeres during vegetative growth" EXACT [PomBase:al] synonym: "increased histone H3-K9 dimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "increased histone H3K9me2 at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2018-02-06T14:49:28Z [Term] id: FYPO:0006362 name: decreased borderline-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the lncRNA borderline are present at lower levels than normal." [PMID:26438724, PomBase:mah] synonym: "decreased accumulation of borderline-derived siRNA" EXACT [PomBase:mah] synonym: "decreased accumulation of siRNAs homologous to borderline" RELATED [PomBase:vw] synonym: "decreased borderline-derived siRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased borderline-derived siRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased brdrRNA-derived siRNA level" EXACT [PomBase:al] synonym: "decreased level of borderline-derived siRNA" EXACT [PomBase:mah] synonym: "decreased level of siRNAs homologous to borderline" RELATED [PomBase:vw] synonym: "reduced borderline-derived siRNA level" EXACT [PomBase:mah] is_a: FYPO:0004205 ! decreased siRNA level created_by: midori creation_date: 2018-02-06T14:52:52Z [Term] id: FYPO:0006363 name: monopolar spindle during meiosis I def: "A physical cellular phenotype in which the spindle forms with microtubules emanating from only one pole during the first meiotic nuclear division." [PMID:24954111, PomBase:mah] comment: Note that an abnormal spindle organization process may, but does not necessarily, result in abnormal spindle morphology. synonym: "fan-shaped spindle during meiosis I" EXACT [PomBase:vw] synonym: "monopolar spindle during first meiotic nuclear division" EXACT [GO:0007127] synonym: "V-shaped spindle during meiosis I" RELATED [PomBase:vw] is_a: FYPO:0005652 ! abnormal spindle morphology during meiosis I created_by: midori creation_date: 2018-02-06T15:03:58Z [Term] id: FYPO:0006364 name: spindle microtubules detached from spindle pole body during meiosis I def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which meiotic spindle microtubules become disconnected from the spindle pole body during the first meiotic nuclear division." [PMID:24954111, PomBase:mah] synonym: "meiotic spindle microtubules detached from spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "non-polar spindle during meiosis I" RELATED [PMID:24954111] synonym: "spindle microtubules detached from SPB during meiosis I" EXACT [PomBase:mah] synonym: "spindle microtubules detached from spindle pole body during first meiotic nuclear division" EXACT [GO:0007127] synonym: "spindle pole body detached from spindle microtubules during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0005652 ! abnormal spindle morphology during meiosis I is_a: FYPO:0006022 ! abnormal spindle pole body morphology during meiosis I created_by: midori creation_date: 2018-02-06T15:05:51Z [Term] id: FYPO:0006365 name: meiotic spindle pole body detached from nucleus def: "A cell phenotype in which the meiotic spindle pole body (SPB) dissociates from the nucleus. Normally the SPB is embedded in the nuclear envelope." [PMID:24954111, PomBase:mah] synonym: "meiotic SPB detached from nucleus" EXACT [PomBase:mah] synonym: "meiotic spindle pole body detached from nuclear envelope" RELATED [PomBase:mah] synonym: "meiotic spindle pole body dissociated from nucleus" EXACT [PomBase:mah] synonym: "spindle pole body detached from nucleus during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0006406 ! abnormal spindle pole body morphology during meiotic cell cycle created_by: midori creation_date: 2018-02-06T15:11:10Z [Term] id: FYPO:0006366 name: abolished meiotic telomere clustering def: "A meiosis phenotype in which meiotic telomere clustering does not occur. Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body." [GO:0045141, PMID:24954111, PomBase:mah] synonym: "abolished bouquet formation" EXACT [PomBase:vw] synonym: "meiotic telomere clustering abolished" EXACT [PomBase:mah] is_a: FYPO:0000172 ! abnormal meiotic telomere clustering created_by: midori creation_date: 2018-02-06T15:20:21Z [Term] id: FYPO:0006368 name: normal spatial extent of centromeric heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a normal (i.e. indistinguishable from wild type) portion of the centromeric region of the chromosome." [PMID:29214404, PomBase:mah] synonym: "normal spatial extent of centromeric heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spatial extent of centromeric heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal spatial extent of centromeric heterochromatin formation" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2018-02-06T15:38:37Z [Term] id: FYPO:0006369 name: increased histone H3-K9 dimethylation at heterochromatin domain during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin domains occurs to a greater extent than normal." [PMID:29214404, PomBase:mah] synonym: "increased histone H3 K9 dimethylation at heterochromatin domain during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at heterochromatin domain during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at heterochromatin domain during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at heterochromatin domain during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at heterochromatin domain during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2018-02-06T15:42:16Z [Term] id: FYPO:0006370 name: decreased protein exchange at subtelomeric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of a protein in cis and trans between heterochromatin domains occurs to a lower extent than normal in regions of subtelomeric heterochromatin." [GO:1990707, PMID:26438724, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein exchange at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein exchange at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein exchange at telomeric heterochromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "decreased protein motility on subtelomeric heterochromatin" EXACT [PomBase:al] synonym: "reduced protein exchange at subtelomeric heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2018-02-09T13:12:19Z [Term] id: FYPO:0006371 name: normal duration of meiotic prophase I def: "A cellular process phenotype in which the duration of prophase of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0003833 ! normal cell cycle phase created_by: midori creation_date: 2018-02-09T13:21:30Z [Term] id: FYPO:0006372 name: incomplete meiotic chromosome segregation, with chromosomal bridge def: "A cellular process phenotype in which homologous chromosomes or sister chromatids do not separate completely during meiosis I or meiosis II, and partially separated DNA masses are connected by one or more bridges formed of chromatin." [PMID:29123917, PomBase:mah] comment: Chromosome lagging may reflect a delay in detachment of homologous chromosomes or sister chromatids from each other ('chromosome separation' as defined by GO:0051307), polewards movement (GO:0016344), or both. synonym: "abnormal meiotic chromosome segregation, with chromosomal bridge" EXACT [PomBase:al] synonym: "incomplete chromosome segregation, with chromosomal bridge, during meiosis" EXACT [PomBase:mah] synonym: "incomplete meiotic chromosome segregation, with chromatin bridge" EXACT [PomBase:mah] is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2018-02-09T14:17:53Z [Term] id: FYPO:0006373 name: increased histone H3-K9 dimethylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a greater extent than normal." [PMID:29214404, PomBase:mah] synonym: "increased histone H3 K9 dimethylation at heterochromatin island during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at heterochromatin island during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at heterochromatin island during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at heterochromatin island during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2018-02-12T14:01:16Z [Term] id: FYPO:0006374 name: abnormal protein processing def: "A cellular process phenotype in which protein processing is abnormal. Protein processing is the cleavage of one or more bonds within a protein that leads to the formation of mature, fully functional protein." [GO:0030163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein cleavage" RELATED [PomBase:vw] synonym: "abnormal protein maturation by peptide bond cleavage" EXACT [GO:0016485] synonym: "abnormal protein maturation by peptide bond hydrolysis" EXACT [GO:0016485] is_a: FYPO:0002274 ! abnormal protein metabolic process created_by: midori creation_date: 2018-02-12T14:06:12Z [Term] id: FYPO:0006375 name: abolished protein processing during nitrogen starvation def: "A cell phenotype in which the protein processing does not occur when the cell is subject to nitrogen starvation. Processing of all proteins or of one or more specific proteins may be affected. Protein processing is any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein." [GO:0016485, PMID:25803873, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein processing during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished protein processing during nitrogen deprivation" EXACT [PomBase:mah] synonym: "protein processing abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0006374 ! abnormal protein processing created_by: midori creation_date: 2018-02-12T14:07:06Z [Term] id: FYPO:0006376 name: decreased protein processing during nitrogen starvation def: "A cellular metabolism phenotype in which the observed occurrence of protein processing is decreased when the cell is subject to nitrogen starvation." [PMID:25803873, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein cleavage during nitrogen starvation" RELATED [PomBase:vw] synonym: "decreased protein maturation by peptide bond cleavage during nitrogen starvation" EXACT [GO:0016485] synonym: "decreased protein maturation by peptide bond hydrolysis during nitrogen starvation" EXACT [GO:0016485] synonym: "decreased protein processing during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased protein processing during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced protein processing during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0006374 ! abnormal protein processing created_by: midori creation_date: 2018-02-12T14:07:06Z [Term] id: FYPO:0006377 name: abnormal protein localization to endoplasmic reticulum def: "A cell phenotype in which the localization of a protein to the endoplasmic reticulum is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the ER and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "abnormal protein localization to ER" EXACT [GO:0005783, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2018-02-12T14:31:02Z [Term] id: FYPO:0006378 name: normal protein localization to endoplasmic reticulum during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in the ER and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to ER during vegetative growth" EXACT [GO:0005783, PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2018-02-12T14:34:40Z [Term] id: FYPO:0006379 name: abolished protein localization to endoplasmic reticulum during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the nucleus does not occur when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to endoplasmic reticulum during nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to endoplasmic reticulum during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to endoplasmic reticulum during nitrogen deprivation" EXACT [PomBase:mah] synonym: "abolished protein localization to ER during nitrogen starvation" EXACT [PomBase:mah] synonym: "protein localization to endoplasmic reticulum abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001375 ! abolished protein localization is_a: FYPO:0008405 ! abolished protein localization to endoplasmic reticulum created_by: midori creation_date: 2018-02-12T14:43:15Z [Term] id: FYPO:0006380 name: normal protein localization to vacuole during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the vacuole is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to vacuole during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein localization to vacuole during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal protein localization to vacuole during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2018-02-12T14:46:48Z [Term] id: FYPO:0006381 name: increased cellular reactive oxygen species level during nitrogen starvation def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "increased cellular reactive oxygen species accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased cellular reactive oxygen species level during nitrogen deprivation" EXACT [PomBase:mah] synonym: "increased cellular ROS accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "increased cellular ROS level during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased ROS accumulation during nitrogen starvation" RELATED [PomBase:al] is_a: FYPO:0000990 ! increased level of substance in cell is_a: FYPO:0002142 ! altered cellular reactive oxygen species level created_by: midori creation_date: 2018-02-12T14:48:35Z [Term] id: FYPO:0006382 name: abnormal cell wall organization during nitrogen starvation def: "A cellular process phenotype in which cell wall organization is abnormal when the cell is subject to nitrogen starvation. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GO:0031505, PomBase:mah] synonym: "abnormal cell wall organisation during nitrogen starvation" EXACT [PomBase:mah] synonym: "abnormal cell wall organization during nitrogen depletion" EXACT [PomBase:mah] synonym: "abnormal cell wall organization during nitrogen deprivation" EXACT [PomBase:mah] synonym: "abnormal fungal-type cell wall organization during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0004805 ! abnormal cell wall organization created_by: midori creation_date: 2018-02-12T14:50:43Z [Term] id: FYPO:0006383 name: abnormal sporulation resulting in formation of ascus containing non-uniform spores and unencapsulated DNA def: "A sporulation phenotype that results in the formation of an ascus that contains spores of non-uniform size and DNA content, as well as DNA that is not contained within any of the spores. There may also be fewer than four spores." [PMID:17632059, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation ascus containing non-uniform spores and unencapsulated DNA" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of asci containing non-uniform spores and unencapsulated DNA" RELATED [PomBase:mah] synonym: "abnormal sporulation resulting in formation of ascus containing non-uniform spores and DNA excluded from spores" EXACT [PomBase:mah, PomBase:vw] is_a: FYPO:0000913 ! abnormal sporulation resulting in formation of ascus containing non-uniform spores created_by: midori creation_date: 2018-02-13T14:06:36Z [Term] id: FYPO:0006384 name: decreased rate of endocytosis during nitrogen starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of endocytosis is decreased when the cell is subject to nitrogen starvation. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein." [PomBase:mah] synonym: "decreased rate of actin-mediated endocytosis during nitrogen starvation" EXACT [PomBase:vw] synonym: "decreased rate of endocytosis during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased rate of endocytosis during nitrogen deprivation" EXACT [PomBase:mah] synonym: "decreased rate of protein internalization during nitrogen starvation" NARROW [PomBase:vw] synonym: "reduced rate of endocytosis during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0003886 ! abnormal endocytosis created_by: midori creation_date: 2018-02-12T14:53:35Z [Term] id: FYPO:0006385 name: normal protein localization to cell tip during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell tip during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein localization to cell end during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2018-02-12T15:05:02Z [Term] id: FYPO:0006386 name: protein abnormally dispersed at shmoo tip def: "A cell phenotype in which a protein that normally localizes to a compact region at the tip of a shmoo, or mating projection, is more dispersed than normal." [PMID:19627505, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormally dispersed protein localization at shmoo tip" EXACT [PomBase:mah] synonym: "protein abnormally dispersed at mating projection tip" EXACT [PomBase:mah] synonym: "protein abnormally dispersed at shmoo projection" RELATED [PomBase:al] is_a: FYPO:0004802 ! abnormal protein localization to shmoo tip created_by: midori creation_date: 2018-02-12T15:16:11Z [Term] id: FYPO:0006387 name: abnormal mitotic spindle pole body organization def: "A cell phenotype in which mitotic spindle pole body organization is abnormal. Mitotic spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the mitotic spindle pole body (SPB)." [GO:1905047, PomBase:mah] synonym: "abnormal mitotic SPB organization" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle pole body organisation" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0003560 ! abnormal spindle pole body organization created_by: midori creation_date: 2018-02-12T15:25:49Z [Term] id: FYPO:0006388 name: abnormal meiotic spindle pole body organization during meiosis I def: "A cell phenotype in which meiotic spindle pole body organization is abnormal during the first meiotic nuclear division. Meiotic spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body (SPB)." [GO:1990395, PomBase:mah] synonym: "abnormal meiotic SPB organization during meiosis I" EXACT [PomBase:mah] synonym: "abnormal meiotic spindle pole body organisation during meiosis I" EXACT [PomBase:mah] synonym: "abnormal spindle pole body organization during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003560 ! abnormal spindle pole body organization created_by: midori creation_date: 2018-02-12T15:26:32Z [Term] id: FYPO:0006389 name: normal meiotic spindle pole body oscillation during prophase I def: "A cellular process phenotype in which the meiotic spindle pole body (SPB) moves rapidly back and forth within the nuclear envelope to a normal (i.e. indistinguishable from wild type) extent during prophase of the first meiotic nuclear division." [PMID:17632059, PomBase:mah] synonym: "normal meiotic SPB oscillation during prophase I" EXACT [PomBase:mah] synonym: "normal meiotic spindle pole body movement during prophase I" EXACT [PomBase:mah] synonym: "normal spindle pole body oscillation during prophase I" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2018-02-12T15:49:27Z [Term] id: FYPO:0006390 name: multiple meiotic spindles def: "A physical cellular phenotype in which a cell contains more than one meiotic spindle during one or both meiotic nuclear divisions." [PomBase:mah] synonym: "additional meiotic spindles present" EXACT [PomBase:mah] synonym: "extra meiotic spindles" EXACT [PomBase:mah] synonym: "increased number of meiotic spindles" EXACT [PomBase:vw] synonym: "meiotic spindles present in greater numbers" EXACT [PomBase:mah] synonym: "multiple spindles during meiosis" EXACT [PomBase:mah] is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2018-02-12T15:59:54Z [Term] id: FYPO:0006391 name: meiotic spindle absent from cell during meiosis def: "A cell phenotype in which the cell does not contain a detectable meiotic spindle during one or both meiotic nuclear divisions." [PomBase:mah] synonym: "absent meiotic spindle during meiosis" EXACT [PomBase:mah] synonym: "meiotic spindle absent from cell during meiotic nuclear division" EXACT [PomBase:mah] synonym: "spindle absent from cell during meiosis" EXACT [PomBase:mah] is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2018-02-12T16:03:13Z [Term] id: FYPO:0006392 name: abolished protein localization to meiotic spindle pole body during meiosis I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abolished during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to meiotic spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to meiotic SPB during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to meiotic spindle pole body during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished protein localization to spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "protein localization to meiotic spindle pole body abolished during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003542 ! abolished protein localization to meiotic spindle pole body created_by: midori creation_date: 2018-02-12T16:19:30Z [Term] id: FYPO:0006393 name: localization phenotype during meiotic cell cycle def: "A cell phenotype that affects the localization of a structure or substance in a cell during a meiotic cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate synonym: "fission yeast localization phenotype during meiotic cell cycle" EXACT [PomBase:mah] synonym: "localisation phenotype during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype created_by: midori creation_date: 2018-02-12T16:25:38Z [Term] id: FYPO:0006394 name: abnormal meiotic spindle localization def: "A cellular process phenotype in which localization of the meiotic spindle is abnormal during one or both meiotic nuclear divisions." [PomBase:mah] synonym: "abnormal establishment of meiotic spindle localization" EXACT [GO:0051295] synonym: "abnormal meiotic spindle localisation" EXACT [PomBase:mah] synonym: "abnormal spindle localization during meiosis" EXACT [PomBase:mah] synonym: "abnormal spindle localization during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0006393 ! localization phenotype during meiotic cell cycle created_by: midori creation_date: 2018-02-12T16:28:28Z [Term] id: FYPO:0006395 name: normal histone H3-K9 acetylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 acetylation at subtelomere during vegetative growth" EXACT [PomBase:vw] synonym: "normal histone H3-K9 acetylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 acetylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "normal histone H3K9 acetylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0043970, PomBase:vw] is_a: FYPO:0003223 ! normal histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2018-02-12T16:37:40Z [Term] id: FYPO:0006396 name: abnormal iMTOC assembly def: "A cellular process phenotype in which interphase microtubule organizing center (iMTOC) assembly is abnormal. iMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an interphase microtubule organizing center." [GO:0031024, PomBase:mah] synonym: "abnormal iMTOC assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal iMTOC assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal iMTOC formation" EXACT [PomBase:mah] synonym: "abnormal interphase microtubule organizing center assembly" EXACT [PomBase:mah] synonym: "abnormal interphase microtubule organizing center formation" EXACT [GO:0031024] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2018-02-13T14:23:43Z [Term] id: FYPO:0006397 name: cytoplasmic microtubules detached from nuclear envelope def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules become detached from the nuclear envelope (NE). Normally, some cytoplasmic microtubules are nucleated at the NE and remain attached." [PMID:16481403, PomBase:mah] comment: This phenotype may result from either absence of the microtubule bundle that would normally attach to the SPB, or from a problem with the SPB-microtubule attachment process. synonym: "cytoplasmic microtubules detached from nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cytoplasmic microtubules detached from nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "cytoplasmic microtubules dissociated from nuclear envelope" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology during vegetative growth is_a: FYPO:0004088 ! abnormal cytoplasmic microtubules created_by: midori creation_date: 2018-02-13T14:39:25Z [Term] id: FYPO:0006398 name: abolished protein phosphorylation during cellular response to leucine starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to leucine starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to leucine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to leucine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to leucine starvation" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2018-02-14T16:06:10Z [Term] id: FYPO:0006399 name: abnormal septin ring morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the septin ring is abnormal." [PomBase:mah] synonym: "abnormal medial cortex septin ring morphology" EXACT [GO:0036391] synonym: "abnormal septin ring morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septin ring morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2018-02-16T15:18:30Z [Term] id: FYPO:0006400 name: increased mitotic DNA replication initiation from inefficient origin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the frequency of DNA replication initiation is higher than normal at inefficient origins, i.e. replication origins that normally rarely fire." [PMID:28903048, PomBase:mah] synonym: "increased DNA replication initiation from inefficient origin during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased DNA replication initiation from inefficient origin during vegetative growth" EXACT [PomBase:mah] synonym: "increased firing of inefficient replication origins" EXACT [PomBase:mah] synonym: "increased mitotic DNA replication initiation at inefficient origin" EXACT [PomBase:mah] synonym: "increased mitotic DNA replication initiation from inefficient replication origin" RELATED [PomBase:mah] is_a: FYPO:0001344 ! abnormal mitotic DNA replication initiation created_by: midori creation_date: 2018-02-20T13:15:47Z [Term] id: FYPO:0006401 name: decreased cellular dNTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular dNTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular dNTP level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased dNTP accumulation" RELATED [PomBase:mah] synonym: "reduced cellular dNTP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-02-20T13:27:42Z [Term] id: FYPO:0006402 name: abolished histone H3-K36 trimethylation at promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 in one or more promoter regions does not occur." [PMID:28903048, PomBase:mah] synonym: "abolished histone H3 K36 trimethylation at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K36 trimethylation at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K36me3 at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K36 trimethylation at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 trimethylation abolished at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 trimethylation absent at promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006261 ! abolished histone H3-K36 trimethylation during vegetative growth created_by: midori creation_date: 2018-02-20T13:30:20Z [Term] id: FYPO:0006403 name: abolished histone H3-K36 dimethylation at promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 36 of histone H3 in one or more promoter regions does not occur." [PMID:28903048, PomBase:mah] synonym: "abolished histone H3 K36 dimethylation at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K36 dimethylation at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K36me2 at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K36 dimethylation at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 dimethylation abolished at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K36 dimethylation absent at promoter during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation during vegetative growth is_a: FYPO:0002919 ! abolished histone H3-K36 methylation during vegetative growth created_by: midori creation_date: 2018-02-20T13:30:39Z [Term] id: FYPO:0006404 name: fragmented spindle pole body def: "A cell phenotype in which the spindle pole body is broken into fragments." [PomBase:mah] synonym: "fragmented SPB" EXACT [PomBase:mah] synonym: "spindle pole body fragmentation" EXACT [PomBase:vw] is_a: FYPO:0004607 ! abnormal spindle pole body morphology created_by: midori creation_date: 2018-02-20T13:47:29Z [Term] id: FYPO:0006405 name: fragmented meiotic spindle pole body def: "A cell phenotype in which the meiotic spindle pole body is broken into fragments." [PomBase:mah] synonym: "fragmented meiotic SPB" EXACT [PomBase:mah] synonym: "fragmented spindle pole body during meiotic cell cycle" EXACT [PomBase:mah] synonym: "meiotic spindle pole body fragmentation" EXACT [PomBase:vw] is_a: FYPO:0006404 ! fragmented spindle pole body created_by: midori creation_date: 2018-02-20T13:47:48Z [Term] id: FYPO:0006406 name: abnormal spindle pole body morphology during meiotic cell cycle def: "A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal during the meiotic cell cycle." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "abnormal SPB morphology during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004607 ! abnormal spindle pole body morphology created_by: midori creation_date: 2018-02-20T13:48:04Z [Term] id: FYPO:0006407 name: sensitive to nitrosative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nitrosative stress." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to nitrosative stress in culture. synonym: "decreased growth during cellular response to nitrosative stress" EXACT [PomBase:mah] synonym: "decreased vegetative cell population growth during cellular response to nitrosative stress" EXACT [PomBase:mah] synonym: "hypersensitive to nitrosative stress" EXACT [PomBase:mah] synonym: "sensitive to nitric oxide" RELATED [PomBase:mah] synonym: "sensitive to nitrosative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to nitrosative stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress during vegetative growth created_by: midori creation_date: 2018-03-01T13:53:42Z [Term] id: FYPO:0006408 name: altered cellular nitric oxide level def: "A cell phenotype in which the amount of nitric oxide measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular nitric oxide accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular nitric oxide level" EXACT [PomBase:mah] synonym: "altered cellular NO level" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2018-03-01T14:00:18Z [Term] id: FYPO:0006409 name: increased cellular nitric oxide level during stationary phase def: "A cell phenotype in which the amount of nitric oxide measured in a cell is higher than normal when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "increased cellular nitric oxide level in stationary phase" EXACT [PomBase:mah] synonym: "increased cellular NO level during stationary phase" EXACT [CHEBI:16480] synonym: "increased nitric oxide accumulation during stationary phase" RELATED [PomBase:mah] is_a: FYPO:0006408 ! altered cellular nitric oxide level created_by: midori creation_date: 2018-03-01T14:01:22Z [Term] id: FYPO:0006410 name: decreased cellular nitric oxide level during stationary phase def: "A cell phenotype in which the amount of nitric oxide measured in a cell is lower than normal when the population in which the cell is found is in stationary phase." [PomBase:mah] synonym: "decreased cellular nitric oxide level in stationary phase" EXACT [PomBase:mah] synonym: "decreased cellular NO level during stationary phase" EXACT [CHEBI:16480] synonym: "decreased nitric oxide accumulation during stationary phase" RELATED [PomBase:mah] synonym: "reduced cellular nitric oxide level during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0006408 ! altered cellular nitric oxide level created_by: midori creation_date: 2018-03-01T14:01:49Z [Term] id: FYPO:0006411 name: abolished histone RNA level oscillation during mitotic cell cycle def: "A gene expression phenotype in which the levels of RNAs that encode histones, which normally vary over the course of the mitotic cell cycle, remain constant. All RNAs encoding histones, or one or more specific histone RNA, may be affected." [PMID:17452352, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abolished histone mRNA level oscillation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished histone RNA level fluctuation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished histone RNA level oscillation during vegetative growth" RELATED [PomBase:mah] synonym: "abolished histone transcript level oscillation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished periodic expression of histone RNA during mitotic cell cycle" EXACT [PomBase:al] synonym: "histone RNA level oscillation abolished during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004988 ! abnormal RNA level oscillation during mitotic cell cycle created_by: midori creation_date: 2018-03-01T14:26:08Z [Term] id: FYPO:0006412 name: decreased level of histone gene mRNA during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) during S phase of the mitotic cell cycle. Histone RNAs are transcribed from genes encoding histones." [PMID:17452352, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased histone gene mRNA accumulation during mitotic S phase" RELATED [PomBase:mah] synonym: "decreased level of histone gene mRNA during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased level of histone gene RNA during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased level of histone gene transcripts during mitotic S phase" EXACT [PomBase:vw] synonym: "reduced level of histone gene mRNA during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0004906 ! decreased level of histone gene mRNA during vegetative growth created_by: midori creation_date: 2018-03-01T14:30:11Z [Term] id: FYPO:0006413 name: increased level of histone gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is higher than normal (i.e. lower than observed in wild-type cells). Histone RNAs are transcribed from genes encoding histones." [PMID:17452352, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased histone gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of histone gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of histone gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of histone gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2018-03-01T14:31:48Z [Term] id: FYPO:0006414 name: increased level of histone gene mRNA during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is higher than normal (i.e. lower than observed in wild-type cells) during interphase of the mitotic cell cycle. Histone RNAs are transcribed from genes encoding histones." [PMID:17452352, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased histone gene mRNA accumulation during mitotic interphase" RELATED [PomBase:mah] synonym: "increased level of histone gene mRNA during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased level of histone gene RNA during mitotic interphase" EXACT [PomBase:mah] synonym: "increased level of histone gene transcripts during mitotic interphase" EXACT [PomBase:vw] is_a: FYPO:0006413 ! increased level of histone gene mRNA during vegetative growth created_by: midori creation_date: 2018-03-01T14:32:44Z [Term] id: FYPO:0006415 name: overlapping meiosis II spindles def: "A spindle phenotype in which the meiotic spindles in adjacent dividing nuclei overlap during meiosis II." [PMID:27304859, PomBase:mah] synonym: "overlapping spindles at meiosis II" EXACT [PomBase:vw] synonym: "overlapping spindles during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2018-03-01T14:53:40Z [Term] id: FYPO:0006417 name: increased duration of resolution of meiotic recombination intermediates def: "A cellular process phenotype in which the duration of the cleavage and rejoining of intermediates formed during meiotic recombination is longer than normal. All intermediates or a subset (such as a specific type or configuration of intermediate) may remain present for longer than normal." [PMID:27304859, PomBase:mah] synonym: "increased duration of joint molecule resolution" EXACT [PomBase:mah] synonym: "persistent meiotic joint molecules" RELATED [PomBase:mah] synonym: "prolonged resolution of meiotic recombination intermediates" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2018-03-01T14:55:52Z [Term] id: FYPO:0006418 name: normal resolution of meiotic recombination intermediates def: "A cellular process phenotype in which the cleavage and rejoining of intermediates formed during meiotic recombination is normal (i.e. indistinguishable from wild type)." [PMID:27304859, PomBase:mah] is_a: FYPO:0007277 ! normal cellular process during meiotic cell cycle created_by: midori creation_date: 2018-03-01T14:57:40Z [Term] id: FYPO:0006419 name: increased duration of Rad51 focus presence during meiotic cell cycle def: "A cell phenotype in which sites at which the protein Rad51 accumulates remain present for longer than normal during the meiotic cell cycle. Normally, Rad51 foci form during prophase I but disappear before metaphase I." [PMID:27304859, PomBase:mah] synonym: "prolonged Rad51 focus presence during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2018-03-01T14:58:58Z [Term] id: FYPO:0006420 name: normal duration of Rad51 focus presence during meiotic cell cycle def: "A cell phenotype in which sites at which the protein Rad51 accumulates remain present for a normal (i.e. indistinguishable from wild type) amount of time during the meiotic cell cycle. Normally, Rad51 foci form during prophase I but disappear before metaphase I." [PMID:27304859, PomBase:mah] is_a: FYPO:0000136 ! cellular physical quality phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2018-03-01T14:59:46Z [Term] id: FYPO:0006421 name: decreased number of Fbh1 foci during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Fbh1 (also called Rad22) accumulates is lower than normal." [PMID:27304859, PomBase:mah] synonym: "decreased number of Fbh1 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced number of Fbh1 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2018-03-01T15:00:53Z [Term] id: FYPO:0006422 name: increased level of histone gene mRNA during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is higher than normal (i.e. lower than observed in wild-type cells) during S phase of the mitotic cell cycle. Histone RNAs are transcribed from genes encoding histones." [PMID:27901072, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased histone gene mRNA accumulation during mitotic S phase" RELATED [PomBase:mah] synonym: "increased level of histone gene mRNA during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased level of histone gene RNA during mitotic S phase" EXACT [PomBase:mah] synonym: "increased level of histone gene transcripts during mitotic S phase" EXACT [PomBase:vw] is_a: FYPO:0006413 ! increased level of histone gene mRNA during vegetative growth created_by: midori creation_date: 2018-03-02T13:20:01Z [Term] id: FYPO:0006423 name: decreased meiotic sister chromatid cohesion at centromere during meiosis I def: "A cellular process phenotype in which cohesion between sister chromatids is decreased in centromeric regions during the first meiotic nuclear division." [PomBase:mah] synonym: "decreased meiotic sister chromatid cohesion at centromere during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased meiotic sister chromatid cohesion, centromeric, during meiosis I" EXACT [GO:0051754] synonym: "decreased sister chromatid cohesion at centromere during meiosis I" EXACT [PomBase:mah] synonym: "reduced meiotic sister chromatid cohesion at centromere during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0005579 ! decreased meiotic sister chromatid cohesion at centromere created_by: midori creation_date: 2018-03-09T13:14:21Z [Term] id: FYPO:0006424 name: abolished meiotic sister chromatid cohesion at centromere during meiosis I def: "A cellular process phenotype in which cohesion between sister chromatids does not occur in centromeric regions during the first meiotic nuclear division." [PomBase:mah] synonym: "abolished meiotic sister chromatid cohesion at centromere during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished meiotic sister chromatid cohesion, centromeric, during meiosis I" EXACT [GO:0051754] synonym: "abolished sister chromatid cohesion at centromere during meiosis I" EXACT [PomBase:mah] synonym: "meiotic sister chromatid cohesion abolished at centromere during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0002092 ! abnormal meiotic sister chromatid cohesion created_by: midori creation_date: 2018-03-09T13:14:39Z [Term] id: FYPO:0006425 name: normal meiotic sister chromatid cohesion at centromere during meiosis I def: "A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) in centromeric regions during the first meiotic nuclear division." [PomBase:mah] synonym: "normal meiotic sister chromatid cohesion at centromere during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal meiotic sister chromatid cohesion, centromeric, during meiosis I" EXACT [GO:0051754] synonym: "normal sister chromatid cohesion at centromere during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0002094 ! normal meiotic sister chromatid cohesion is_a: FYPO:0004667 ! normal meiotic sister chromatid cohesion at centromere created_by: midori creation_date: 2018-03-09T13:15:01Z [Term] id: FYPO:0006426 name: normal attachment of spindle microtubules to kinetochore during meiosis I def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal attachment of spindle microtubules to kinetochore during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [PomBase:mah] synonym: "normal attachment of spindle microtubules to meiosis I kinetochore" EXACT [PomBase:vw] synonym: "normal kinetochore mono-orientation at meiosis I" EXACT [PomBase:vw] synonym: "normal sister kinetochore mono-orientation" EXACT [GO:0051455] is_a: FYPO:0003570 ! normal attachment of spindle microtubules to kinetochore is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2018-03-09T13:15:09Z [Term] id: FYPO:0006427 name: abolished attachment of spindle microtubules to kinetochore during meiosis I def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division does not occur." [PomBase:mah] synonym: "abolished attachment of spindle microtubules to kinetochore during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [PomBase:mah] synonym: "abolished attachment of spindle microtubules to meiosis I kinetochore" EXACT [PomBase:vw] synonym: "abolished kinetochore mono-orientation at meiosis I" EXACT [PomBase:vw] synonym: "abolished sister kinetochore mono-orientation" EXACT [GO:0051455] synonym: "attachment of spindle microtubules to kinetochore abolished during meiosis I" EXACT [PomBase:mah] synonym: "attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation abolished" EXACT [GO:0051455] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore is_a: FYPO:0003250 ! premature septum assembly relationship: has_part FYPO:0003250 ! premature septum assembly created_by: midori creation_date: 2018-03-09T13:19:30Z [Term] id: FYPO:0006428 name: normal mitotic sister chromatid biorientation def: "A cellular process phenotype in which the stable attachment of sister chromatids to microtubules emanating from opposite poles of the mitotic spindle during metaphase plate congression is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal sister chromatid biorientation during mitosis" EXACT [PomBase:mah] synonym: "normal sister chromatid biorientation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal sister chromatid biorientation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0003570 ! normal attachment of spindle microtubules to kinetochore is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2018-03-09T13:19:34Z [Term] id: FYPO:0006429 name: normal histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in subtelomeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 methylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "normal histone H3-K9 methylation at subtelomeres during vegetative growth" EXACT [PomBase:al] synonym: "normal histone H3-K9 methylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 methylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "normal histone H3K9me2 at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0051567, PomBase:mah] synonym: "normal histone lysine H3 K9 methylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2018-03-09T13:19:39Z [Term] id: FYPO:0006430 name: inviable mononucleate vegetative cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and contains a single nucleus." [PomBase:mah] synonym: "inviable mononucleate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000060 ! mononucleate vegetative cell relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2018-03-09T13:19:43Z [Term] id: FYPO:0006431 name: enlarged mitotic spindle pole body def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body is larger than normal." [PomBase:mah] synonym: "enlarged mitotic SPB" EXACT [] {comment="PomBase:vw"} synonym: "enlarged spindle pole body during mitotic cell cycle" EXACT [PomBase:mah] synonym: "enlarged spindle pole body during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001474 ! abnormal mitotic spindle pole body morphology created_by: midori creation_date: 2018-03-09T13:19:49Z [Term] id: FYPO:0006432 name: normal vesicle-mediated transport during vegetative growth def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term can be used for protein transport or for the movement of other substances (e.g. lipids or ions) via vesicles. If it is used for a protein transport phenotype, we recommend noting which protein(s) were used in the assay. synonym: "normal vesicle-mediated protein transport during vegetative growth" NARROW [PomBase:mah] synonym: "normal vesicle-mediated transport during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2018-03-09T13:19:53Z [Term] id: FYPO:0006433 name: abnormal tubular endoplasmic reticulum morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the tubular endoplasmic reticulum (ER) is abnormal. The tubular ER is the portion of the ER that consists of tubules having membranes with high curvature in cross-section." [GO:0071782, PomBase:mah] synonym: "abnormal endoplasmic reticulum tubular network morphology" EXACT [GO:0071782] synonym: "abnormal ER tubular network morphology" EXACT [GO:0071782] synonym: "abnormal tubular endoplasmic reticulum morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal tubular endoplasmic reticulum morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal tubular ER morphology" EXACT [PomBase:mah] is_a: FYPO:0000354 ! abnormal endoplasmic reticulum morphology created_by: midori creation_date: 2018-03-09T13:20:19Z [Term] id: FYPO:0006434 name: decreased protein localization to medial cortical node, with protein distributed in cell cortex, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical node of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortical node." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "cortical drift" RELATED [PomBase:vw] synonym: "decreased protein localisation to medial cortical node during vegetative growth, with protein distributed in cell cortex" EXACT [PomBase:mah] synonym: "decreased protein localisation to medial cortical node, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cytokinetic nodes, with protein distributed in cell cortex, during vegetative growth" RELATED [PomBase:mah] synonym: "decreased protein localization to medial cortical node during vegetative growth, with protein distributed in cell cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to medial cortical node during vegetative growth, with protein distributed in cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to medial cortical node, with protein distributed in cell cortex, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to medial cortical node, with protein distributed in cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein recruitment to medial cortical node, with protein distributed in cell cortex, during vegetative growth" RELATED [PomBase:mah] synonym: "reduced protein localization to medial cortical node during vegetative growth, with protein distributed in cell cortex" EXACT [PomBase:mah] synonym: "reduced protein localization to medial cortical node, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006326 ! decreased protein localization to medial cortical node created_by: midori creation_date: 2018-03-09T13:20:24Z [Term] id: FYPO:0006435 name: increased FAD binding def: "A molecular function phenotype in which occurrence of FAD binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds FAD more than wild type, or that a mutation in one gene increases FAD binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "increased oxidized flavin adenine dinucleotide binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2018-03-09T13:20:28Z [Term] id: FYPO:0006436 name: abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate def: "A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage." [PomBase:mah] synonym: "abnormal intra-S phase DNA damage checkpoint during cellular response to methyl methanesulfonate" EXACT [GO:0031573] synonym: "abnormal mitotic S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint activation during cellular response to methyl methanesulfonate" EXACT [PomBase:al] synonym: "abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0000007 ! abnormal S-phase DNA damage checkpoint is_a: FYPO:0005268 ! abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate created_by: midori creation_date: 2018-03-09T13:20:32Z [Term] id: FYPO:0006437 name: normal mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate def: "A cell cycle checkpoint phenotype in which the mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage." [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint activation during cellular response to methyl methanesulfonate" EXACT [PomBase:al] synonym: "normal mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0001705 ! normal mitotic DNA damage checkpoint is_a: FYPO:0005373 ! normal mitotic cell cycle regulation during cellular response to methyl methanesulfonate created_by: midori creation_date: 2018-03-09T13:20:36Z [Term] id: FYPO:0006438 name: alkylation damage repair intermediates absent def: "A cell phenotype in which DNA molecules corresponding to alkylation damage repair intermediates are absent from the cell during DNA replication." [PMID:23071723, PomBase:mah] synonym: "alkylation damage repair intermediates absent during mitotic cell cycle" RELATED [PomBase:mah] synonym: "alkylation damage repair intermediates absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2018-03-09T13:20:40Z [Term] id: FYPO:0006439 name: increased level of X-shaped replication intermediates def: "A cell phenotype in which the level of X-shaped DNA replication intermediates is greater than normal. X-shaped intermediates may be formed by replication forks moving bidirectionally from outside the region, or by the increased formation or persistence of Holliday junctions or similar recombination intermediates." [PMID:23071723, PomBase:mah] synonym: "abnormal proportion of X-shaped replication intermediates" RELATED [PomBase:mah] synonym: "increased level of X-shaped DNA replication intermediates" EXACT [PomBase:mah] synonym: "increased level of X-shaped replication intermediates during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of X-shaped replication intermediates during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2018-03-09T13:20:55Z [Term] id: FYPO:0006440 name: abolished protein kinase activity during cellular response to hydroxyurea def: "A molecular function phenotype in which a protein kinase activity is absent during a cellular response to hydroxyurea." [PomBase:mah] synonym: "abolished protein kinase activity during cellular response to HU" EXACT [PomBase:mah] synonym: "protein kinase activity abolished during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001384 ! abolished protein kinase activity created_by: midori creation_date: 2018-03-09T13:21:01Z [Term] id: FYPO:0006441 name: increased protein kinase activity during cellular response to hydroxyurea def: "A molecular function phenotype in which the observed rate of a protein kinase activity is increased during a cellular response to hydroxyurea." [PomBase:mah] synonym: "increased protein kinase activity during cellular response to HU" EXACT [PomBase:mah] is_a: FYPO:0002700 ! increased protein kinase activity created_by: midori creation_date: 2018-03-09T13:21:04Z [Term] id: FYPO:0006442 name: constitutively activated sterol regulatory element binding protein cleavage def: "A cellular process phenotype in which the proteolytic processing of sterol regulatory element binding protein (SREBP) into its transcriptionally active form is activated continuously. Normally, SREBP is cleaved only in response to altered levels of one or more lipids." [GO:0035103, PMID:18503029, PomBase:mah] synonym: "constitutively activated SREBP cleavage" EXACT [PomBase:mah] synonym: "constitutively activated sterol regulatory element binding protein cleavage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "constitutively activated sterol regulatory element binding protein cleavage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001421 ! abnormal protein processing during vegetative growth created_by: midori creation_date: 2018-03-09T13:21:08Z [Term] id: FYPO:0006443 name: decreased transcription of amino acid biosynthesis genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of amino acid biosynthesis genes from RNA polymerase II promoters occurs to a lower extent than normal. Amino acid biosynthesis genes are those whose products are involved in amino acid biosynthetic processes." [PMID:29432178, PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes from RNA pol II promoter" EXACT [PomBase:mah] synonym: "reduced transcription of amino acid biosynthesis genes" EXACT [PomBase:mah] is_a: FYPO:0005229 ! decreased transcription from RNA polymerase II promoter during vegetative growth created_by: midori creation_date: 2018-03-19T13:35:26Z [Term] id: FYPO:0006444 name: abnormal transcriptional response to amino acid starvation def: "A conjugation phenotype in which regulation of transcription in response to starvation for one or more amino acids is abnormal." [PMID:29432178, PomBase:mah] synonym: "abnormal regulation of transcription from RNA polymerase II promoter in response to amino acid starvation" EXACT [PomBase:mah] is_a: FYPO:0001339 ! abnormal cellular response to starvation during vegetative growth is_a: FYPO:0004527 ! abnormal regulation of transcription during vegetative growth created_by: midori creation_date: 2018-03-19T14:17:05Z [Term] id: FYPO:0006445 name: decreased translation of amino acid biosynthesis proteins during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more proteins involved in amino acid biosynthesis is decreased." [PMID:29432178, PomBase:mah] synonym: "decreased translation of amino acid biosynthesis genes during vegetative growth" EXACT [PomBase:vw] synonym: "decreased translation of amino acid biosynthesis mRNAs during vegetative growth" EXACT [PomBase:mah] synonym: "decreased translation of amino acid biosynthesis proteins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced translation of amino acid biosynthesis proteins during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001798 ! decreased translation created_by: midori creation_date: 2018-03-19T14:19:26Z [Term] id: FYPO:0006446 name: increased mitochondrial pre-mRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in the mitochondrion is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "accumulation of mitochondrial pre-mRNA transcripts" RELATED [PomBase:vw] synonym: "increased mitochondrial pre-mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitochondrial pre-mRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitochondrial pre-mRNA transcript level" EXACT [PomBase:vw] synonym: "increased mitochondrial re-mRNA accumulation" RELATED [PomBase:mah] synonym: "increased pre-mRNA level in mitochondrion" EXACT [PomBase:mah] is_a: FYPO:0001908 ! increased pre-mRNA level is_a: FYPO:0003424 ! increased mitochondrial RNA level created_by: midori creation_date: 2018-03-19T13:35:47Z [Term] id: FYPO:0006447 name: abolished protein localization to cleavage furrow during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cleavage furrow does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to cleavage furrow during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from cleavage furrow during vegetative growth" RELATED [PomBase:mah] synonym: "protein localization to cleavage furrow abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth is_a: FYPO:0005570 ! abnormal protein localization to cell periphery during vegetative growth created_by: midori creation_date: 2018-03-19T14:34:47Z [Term] id: FYPO:0006448 name: decreased rate of protein localization from Golgi apparatus to cleavage furrow def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein from the Golgi apparatus to the cleavage furrow ring is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased rate of protein localisation from Golgi apparatus to cleavage furrow" EXACT [PomBase:mah] synonym: "decreased rate of protein localization from Golgi apparatus to cleavage furrow during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of protein localization from Golgi apparatus to cleavage furrow during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of protein localization from Golgi apparatus to cleavage furrow" EXACT [PomBase:mah] is_a: FYPO:0001401 ! abnormal protein localization to cell division site is_a: FYPO:0005570 ! abnormal protein localization to cell periphery during vegetative growth created_by: midori creation_date: 2018-03-19T14:36:17Z [Term] id: FYPO:0006449 name: decreased rate of histone H3 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of histone H3 acetylation is lower extent than normal." [PMID:26401015, PomBase:mah] synonym: "decreased rate of histone H3 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced rate of histone H3 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002361 ! abnormal histone H3 acetylation during vegetative growth created_by: midori creation_date: 2018-03-21T11:04:39Z [Term] id: FYPO:0006450 name: altered histone H3 acetyltransferase substrate specificity def: "A molecular function phenotype in which the substrate specificity of a gene product that executes histone H3 acetyltransferase activity is altered. For example, preference for modified (e.g. methylated) H3 molecules may be enhanced or diminished." [PMID:26401015, PomBase:mah] synonym: "altered H3 histone acetyltransferase substrate specificity" EXACT [GO:0010484] is_a: FYPO:0003347 ! altered substrate specificity is_a: FYPO:0006453 ! abnormal histone acetyltransferase activity created_by: midori creation_date: 2018-03-21T11:06:36Z [Term] id: FYPO:0006451 name: decreased methylated histone binding def: "A molecular function phenotype in which methylated histone binding by a gene product (usually a protein) in a mutant occurs to a lower extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "reduced methylated histone binding" EXACT [PomBase:mah] is_a: FYPO:0004231 ! abnormal methylated histone binding created_by: midori creation_date: 2018-03-21T11:25:12Z [Term] id: FYPO:0006452 name: decreased histone H3 acetyltransferase processivity def: "A molecular function phenotype in which the observed processivity of a histone H3 acetyltransferase activity is lower than normal. Processivity refers to the number of methylation reactions catalyzed (methyl residues added) per histone binding event." [PMID:26401015, PomBase:mah] synonym: "decreased H3 histone acetyltransferase processivity" EXACT [GO:0010484] synonym: "reduced histone H3 acetyltransferase processivity" EXACT [PomBase:mah] is_a: FYPO:0006453 ! abnormal histone acetyltransferase activity created_by: midori creation_date: 2018-03-21T11:26:42Z [Term] id: FYPO:0006453 name: abnormal histone acetyltransferase activity def: "A molecular function phenotype in which the observed rate or other catalytic property of a histone acetyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal histone acetylase activity" EXACT [GO:0004402] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2018-03-21T11:28:11Z [Term] id: FYPO:0006454 name: abnormal protein localization to meiotic spindle def: "A cell phenotype in which the localization of a protein to the meiotic spindle is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to meiotic spindle" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle during meiosis" EXACT [PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0007863 ! abnormal protein localization to spindle created_by: midori creation_date: 2018-03-23T11:44:14Z [Term] id: FYPO:0006455 name: abolished protein localization to meiotic spindle during meiosis I def: "A cell phenotype in which the localization of a protein to the meiotic spindle is abolished during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to meiosis I spindle" EXACT [PomBase:al] synonym: "abolished protein localization to meiotic spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished protein localization to spindle during meiosis I" EXACT [PomBase:mah] synonym: "protein localization to meiotic spindle abolished during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle created_by: midori creation_date: 2018-03-23T11:44:22Z [Term] id: FYPO:0006456 name: abolished protein localization to meiotic spindle during meiosis II def: "A cell phenotype in which the localization of a protein to the meiotic spindle is abolished during the second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to meiotic spindle during meiosis II" EXACT [PomBase:mah] synonym: "abolished protein localization to meiosis II spindle" EXACT [PomBase:al] synonym: "abolished protein localization to meiotic spindle pole body during second meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished protein localization to spindle during meiosis II" EXACT [PomBase:mah] synonym: "protein localization to meiotic spindle abolished during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle created_by: midori creation_date: 2018-03-23T11:44:26Z [Term] id: FYPO:0006457 name: abolished protein localization to centromere central core during meiosis I def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is abolished during the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to centromere central core during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localisation to chromatin at centromere central core during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to centromere central core during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at centromere central core during meiosis I" EXACT [PomBase:mah] synonym: "protein localization to centromere central core abolished during meiosis I" EXACT [PomBase:mah] synonym: "protein localization to chromatin at centromere central core abolished during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle is_a: FYPO:0006161 ! abolished protein localization to chromatin during meiosis I is_a: FYPO:0006529 ! abnormal protein localization to centromere during meiotic cell cycle created_by: midori creation_date: 2018-03-23T11:52:43Z [Term] id: FYPO:0006458 name: abnormal histone modification def: "A cellular process phenotype that affects histone modification." [PomBase:mah] is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2018-03-23T12:00:09Z [Term] id: FYPO:0006459 name: abnormal protein modification during meiotic cell cycle def: "A cellular process phenotype in which protein modification is abnormal during the meiotic cell cycle. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2018-03-23T12:01:19Z [Term] id: FYPO:0006460 name: increased histone H2A phosphorylation at protein coding gene during meiosis I def: "A cellular process phenotype in which histone H2A phosphorylation occurs to a greater extent than normal in regions containing protein-coding genes during the first meiotic nuclear division. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:19965387, PomBase:mah] synonym: "increased histone H2A phosphorylation at protein coding gene during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation at protein-coding gene during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003565 ! increased protein phosphorylation during meiosis I is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: midori creation_date: 2018-03-23T12:07:57Z [Term] id: FYPO:0006461 name: increased histone H2A phosphorylation at telomere during meiosis I def: "A cellular process phenotype in which histone H2A phosphorylation occurs to a greater extent than normal in telomeric regions during the first meiotic nuclear division. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:19965387, PomBase:mah] synonym: "increased histone H2A phosphorylation at telomere during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased telomeric histone H2A phosphorylation during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003565 ! increased protein phosphorylation during meiosis I is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: midori creation_date: 2018-03-23T12:12:20Z [Term] id: FYPO:0006462 name: increased histone H2A phosphorylation at silent mating-type cassette during meiosis I def: "A cellular process phenotype in which histone H2A phosphorylation occurs to a greater extent than normal at the silent mating-type cassette during the first meiotic nuclear division. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PMID:19965387, PomBase:mah] synonym: "increased histone H2A phosphorylation at silent mating-type cassette during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation at silent mating-type region during meiosis I" EXACT [PomBase:al] is_a: FYPO:0003565 ! increased protein phosphorylation during meiosis I is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: midori creation_date: 2018-03-23T12:13:32Z [Term] id: FYPO:0006463 name: abnormal mRNA cleavage and polyadenylation specificity factor complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA cleavage and polyadenylation specificity factor complex assembly is abnormal." [PMID:27401558, PomBase:mah] synonym: "abnormal mRNA cleavage and polyadenylation specificity factor complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mRNA cleavage and polyadenylation specificity factor complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2018-03-26T15:58:40Z [Term] id: FYPO:0006464 name: abnormal telomere length during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomere length is abnormal." [PomBase:mah] comment: Note that an abnormal telomere organization process may, but does not necessarily, result in abnormal telomere morphology. synonym: "abnormal telomere length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002254 ! abnormal telomere morphology during vegetative growth is_a: FYPO:0006509 ! abnormal telomere length created_by: midori creation_date: 2018-03-28T11:17:51Z [Term] id: FYPO:0006465 name: altered mature ncRNA level during vegetative growth def: "A cell phenotype in which the amount of mature non-coding RNA (ncRNA) measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total ncRNA or a specific ncRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal ncRNA level during vegetative growth" BROAD [PomBase:mah] synonym: "altered cellular mature ncRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered mature ncRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered mature ncRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "altered mature non-coding RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001326 ! altered RNA level during vegetative growth created_by: midori creation_date: 2018-03-28T11:30:11Z [Term] id: FYPO:0006466 name: decreased mature ncRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is lower than normal. Total ncRNA or a specific ncRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature ncRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature ncRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature ncRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature ncRNA transcript level" EXACT [PomBase:vw] synonym: "decreased mature non-coding RNA level" EXACT [PomBase:mah] synonym: "decreased ncRNA level" BROAD [PomBase:mah] synonym: "reduced mature ncRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0006465 ! altered mature ncRNA level during vegetative growth created_by: midori creation_date: 2018-03-28T11:30:22Z [Term] id: FYPO:0006467 name: increased mature ncRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is higher than normal. Total ncRNA or a specific ncRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mature ncRNA accumulation" RELATED [PomBase:mah] synonym: "increased mature ncRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mature ncRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mature ncRNA transcript level" EXACT [PomBase:vw] synonym: "increased mature non-coding RNA level" EXACT [PomBase:mah] synonym: "increased ncRNA level" BROAD [PomBase:mah] is_a: FYPO:0006465 ! altered mature ncRNA level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2018-03-28T11:34:21Z [Term] id: FYPO:0006468 name: altered mature rRNA level during vegetative growth def: "A cell phenotype in which the amount of mature ribosomal RNA (rRNA) measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total rRNA or a specific rRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "abnormal rRNA level during vegetative growth" BROAD [PomBase:mah] synonym: "altered cellular mature rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered mature ribosomal RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered mature rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered mature rRNA transcript level during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0005996 ! altered rRNA or precursor level created_by: midori creation_date: 2018-03-28T11:45:15Z [Term] id: FYPO:0006469 name: normal mature ncRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total ncRNA or a specific ncRNA may be measured." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mature ncRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature ncRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature ncRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature ncRNA transcript level" EXACT [PomBase:mah] synonym: "normal mature non-coding RNA level" EXACT [PomBase:mah] synonym: "normal ncRNA level" BROAD [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2018-03-28T11:47:34Z [Term] id: FYPO:0006470 name: decreased mature rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature ribosomal RNA (rRNA) measured in a cell is lower than normal. Total rRNA or a specific rRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mature ribosomal RNA level" EXACT [PomBase:mah] synonym: "decreased mature rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased mature rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mature rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature rRNA transcript level" EXACT [PomBase:vw] synonym: "decreased rRNA level" BROAD [PomBase:mah] synonym: "reduced mature rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0006468 ! altered mature rRNA level during vegetative growth created_by: midori creation_date: 2018-03-28T12:10:53Z [Term] id: FYPO:0006472 name: decreased translation of amino acid biosynthesis proteins in response to amino acid starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more proteins involved in amino acid biosynthesis is decreased in response to starvation for one or more amino acids." [PMID:29432178, PomBase:mah] synonym: "decreased translation of amino acid biosynthesis genes in response to amino acid starvation" EXACT [PomBase:mah] synonym: "decreased translation of amino acid biosynthesis mRNAs in response to amino acid starvation" EXACT [PomBase:mah] synonym: "decreased translation of amino acid biosynthesis proteins during cellular response to amino acid starvation" EXACT [PomBase:mah] synonym: "decreased translation of amino acid biosynthesis proteins in response to amino acid starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased translation of amino acid biosynthesis proteins in response to amino acid starvation during vegetative growth" EXACT [PomBase:vw] synonym: "reduced translation of amino acid biosynthesis proteins in response to amino acid starvation" EXACT [PomBase:mah] is_a: FYPO:0006445 ! decreased translation of amino acid biosynthesis proteins during vegetative growth created_by: midori creation_date: 2018-04-04T11:27:25Z [Term] id: FYPO:0006473 name: decreased transcription of amino acid biosynthesis genes in response to amino acid starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of amino acid biosynthesis genes from RNA polymerase II promoters occurs to a lower extent than normal in response to starvation for one or more amino acids. Amino acid biosynthesis genes are those whose products are involved in amino acid biosynthetic processes." [PMID:29432178, PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes during cellular response to amino acid starvation" EXACT [PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes from RNA pol II promoter in response to amino acid starvation" EXACT [PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes in response to amino acid starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription of amino acid biosynthesis genes in response to amino acid starvation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription of amino acid biosynthesis genes in response to amino acid starvation" EXACT [PomBase:mah] is_a: FYPO:0006443 ! decreased transcription of amino acid biosynthesis genes created_by: midori creation_date: 2018-04-04T11:41:08Z [Term] id: FYPO:0006474 name: abnormal regulation of translation in response to amino acid starvation def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to starvation for one or more amino acids is abnormal." [PMID:29432178, PomBase:mah] synonym: "abnormal regulation of translation during cellular response to amino acid starvation" EXACT [PomBase:mah] synonym: "abnormal regulation of translation in response to amino acid starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of translation in response to amino acid starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0005044 ! translation regulation phenotype during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2018-04-04T11:47:41Z [Term] id: FYPO:0006475 name: mitotic spindle collapse def: "A cell phenotype in which a short mitotic spindle assembles, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink." [PMID:15147872, PMID:23885124, PMID:25375240, PMID:27697865, PomBase:mah] synonym: "broken mitotic spindle" RELATED [PomBase:vw] synonym: "mitotic spindle breakage" EXACT [PMID:27697865] synonym: "mitotic spindle collapse during vegetative growth" EXACT [PomBase:mah] synonym: "spindle collapse during mitosis" EXACT [PomBase:mah] synonym: "spindle collapse during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0006048 ! unstable mitotic spindle created_by: midori creation_date: 2018-04-04T12:12:40Z [Term] id: FYPO:0006476 name: premature mitotic metaphase/anaphase transition def: "A cellular process phenotype in which the onset of anaphase of the mitotic cell cycle begins earlier than normal." [PomBase:mah] synonym: "advanced mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of metaphase during mitosis" RELATED [PomBase:mah] synonym: "decreased duration of mitotic metaphase" RELATED [PomBase:mah] synonym: "premature cell cycle passage through mitotic metaphase-anaphase transition" EXACT [PomBase:mah] synonym: "premature cell cycle progression through mitotic metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "premature metaphase/anaphase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature mitotic metaphase/anaphase phase transition" EXACT [PomBase:mah] synonym: "premature mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] synonym: "premature onset of mitotic anaphase" EXACT [PomBase:vw] is_a: FYPO:0006477 ! abnormal mitotic metaphase/anaphase transition relationship: has_output FYPO:0006490 ! decreased duration of mitotic M phase created_by: midori creation_date: 2018-04-04T15:01:14Z [Term] id: FYPO:0006477 name: abnormal mitotic metaphase/anaphase transition def: "A cellular process phenotype in which the metaphase/anaphase transition of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal cell cycle passage through mitotic metaphase-anaphase transition" EXACT [PomBase:mah] synonym: "abnormal cell cycle progression through the metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "abnormal metaphase/anaphase transition during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic metaphase/anaphase cell cycle phase transition" EXACT [PomBase:mah] synonym: "abnormal mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal onset of mitotic anaphase" RELATED [PomBase:vw] is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2018-04-04T15:02:33Z [Term] id: FYPO:0006478 name: decreased mitotic cohesin dsDNA (leading strand) loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin dsDNA (leading strand) loading is decreased during the mitotic cell cycle. Cohesin dsDNA (leading strand) loading is the topological linking of a cohesin ring complex to double-stranded DNA, i.e. the leading strand, in chromatin." [GO:0062021, PomBase:mah] synonym: "decreased cohesin dsDNA (leading strand) loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased cohesin dsDNA (leading strand) loading during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic cohesin association with dsDNA (leading strand) chromatin" EXACT [GO:0071921] synonym: "decreased mitotic cohesin localization to dsDNA (leading strand) chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "reduced mitotic cohesin dsDNA (leading strand) loading" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2018-04-06T14:47:18Z [Term] id: FYPO:0006479 name: abnormal cohesin loading def: "A cell phenotype in which cohesin loading is abnormal. Cohesin loading is the topological linking of a cohesin ring complex to chromatin." [GO:0071921, PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal cohesin association with chromatin" EXACT [GO:0071921] synonym: "abnormal cohesin localisation to chromatin" EXACT [GO:0071921] synonym: "abnormal cohesin localization to chromatin" EXACT [GO:0071921] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2018-04-06T14:51:50Z [Term] id: FYPO:0006480 name: normal cohesin loading def: "A cell phenotype in which cohesin loading is normal (i.e. indistinguishable from wild type). Cohesin loading is the topological linking of a cohesin ring complex to chromatin." [GO:0071921, PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cohesin association with chromatin" EXACT [GO:0071921] synonym: "normal cohesin localisation to chromatin" EXACT [GO:0071921] synonym: "normal cohesin localization to chromatin" EXACT [GO:0071921] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0002333 ! protein localization phenotype created_by: midori creation_date: 2018-04-06T14:54:41Z [Term] id: FYPO:0006481 name: increased mitotic cohesin ssDNA (lagging strand) loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin ssDNA (lagging strand) loading is increased during the mitotic cell cycle. Cohesin ssDNA (lagging strand) loading is the topological linking of a cohesin ring complex to single-stranded DNA, i.e. the lagging strand, in chromatin." [GO:0062022, PomBase:mah] synonym: "increased cohesin ssDNA (lagging strand) loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased cohesin ssDNA (lagging strand) loading during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitotic cohesin association with ssDNA (lagging strand) chromatin" EXACT [GO:0071921] synonym: "increased mitotic cohesin localization to ssDNA (lagging strand) chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "increased second-DNA capture" EXACT [GO:0062022, PomBase:vw] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0000682 ! abnormal regulation of molecular function is_a: FYPO:0006479 ! abnormal cohesin loading created_by: midori creation_date: 2018-04-06T14:56:43Z [Term] id: FYPO:0006482 name: normal mitotic cohesin ssDNA (lagging strand) loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin ssDNA (lagging strand) loading is normal (i.e. indistinguishable from wild type) during the mitotic cell cycle. Cohesin ssDNA (lagging strand) loading is the topological linking of a cohesin ring complex to single-stranded DNA, i.e. the lagging strand, in chromatin." [GO:0062022, PomBase:mah] synonym: "normal cohesin ssDNA (lagging strand) loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal cohesin ssDNA (lagging strand) loading during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic cohesin association with ssDNA (lagging strand) chromatin" EXACT [GO:0071921] synonym: "normal mitotic cohesin localization to ssDNA (lagging strand) chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "normal second-DNA capture" EXACT [GO:0062022, PomBase:vw] is_a: FYPO:0006480 ! normal cohesin loading created_by: midori creation_date: 2018-04-06T14:59:15Z [Term] id: FYPO:0006483 name: decreased mitotic cohesin ssDNA (lagging strand) loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin ssDNA (lagging strand) loading is decreased during the mitotic cell cycle. Cohesin ssDNA (lagging strand) loading is the topological linking of a cohesin ring complex to single-stranded DNA, i.e. the lagging strand, in chromatin." [GO:0062022, PomBase:mah] synonym: "decreased cohesin ssDNA (lagging strand) loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased cohesin ssDNA (lagging strand) loading during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic cohesin association with ssDNA (lagging strand) chromatin" EXACT [GO:0071921] synonym: "decreased mitotic cohesin localization to ssDNA (lagging strand) chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "reduced mitotic cohesin ssDNA (lagging strand) loading" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2018-04-06T15:01:58Z [Term] id: FYPO:0006484 name: abolished mitotic cohesin dsDNA (leading strand) loading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin dsDNA (leading strand) loading does not occur during the mitotic cell cycle. Cohesin dsDNA (leading strand) loading is the topological linking of a cohesin ring complex to double-stranded DNA of the leading strand in chromatin." [GO:0062021, PomBase:mah] synonym: "abolished cohesin dsDNA (leading strand) loading during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished cohesin dsDNA (leading strand) loading during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic cohesin association with dsDNA (leading strand) chromatin" EXACT [GO:0071921] synonym: "abolished mitotic cohesin localization to dsDNA (leading strand) chromatin" EXACT [GO:0071921, PomBase:mah] synonym: "mitotic cohesin dsDNA (leading strand) loading abolished" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2018-04-06T15:03:25Z [Term] id: FYPO:0006485 name: decreased cellular phosphatidylinositol-3,4-bisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4-bisphosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate level" EXACT [CHEBI:16152] synonym: "decreased cellular phosphatidylinositol-3,4-bisphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-3,4-bisphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PI(3,4)P2 level" EXACT [PomBase:vw] synonym: "reduced cellular phosphatidylinositol-3,4-bisphosphate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-04-06T15:26:30Z [Term] id: FYPO:0006486 name: decreased cellular phosphatidylinositol-3,4,5-trisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate level" EXACT [CHEBI:16618] synonym: "decreased cellular phosphatidylinositol-3,4,5-trisphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-3,4,5-trisphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PI(3,4,5)P3 level" EXACT [PomBase:vw] synonym: "reduced cellular phosphatidylinositol-3,4,5-trisphosphate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-04-06T15:30:16Z [Term] id: FYPO:0006487 name: increased cellular phosphatidylinositol-3,4-bisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4-bisphosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate level" EXACT [CHEBI:16152] synonym: "increased cellular phosphatidylinositol-3,4-bisphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphatidylinositol-3,4-bisphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PI(3,4)P2 level" EXACT [PomBase:vw] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-04-06T15:32:18Z [Term] id: FYPO:0006488 name: increased cellular phosphatidylinositol-3,4,5-trisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate level" EXACT [CHEBI:16618] synonym: "increased cellular phosphatidylinositol-3,4,5-trisphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular phosphatidylinositol-3,4,5-trisphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PI(3,4,5)P3 level" EXACT [PomBase:vw] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-04-06T15:32:31Z [Term] id: FYPO:0006489 name: normal cellular phosphatidylinositol-3-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular phosphatidylinositol-3-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylinositol-3-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular PI(3)P level" EXACT [PomBase:vw] synonym: "normal cellular PI-3-P level" EXACT [PomBase:al] synonym: "normal PI-3-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2018-04-06T15:37:10Z [Term] id: FYPO:0006490 name: decreased duration of mitotic M phase def: "A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "decreased duration of M phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased duration of mitosis" RELATED [PomBase:mah] synonym: "decreased duration of mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of mitosis during vegetative growth" RELATED [PomBase:mah] synonym: "decreased duration of mitotic nuclear division" RELATED [PomBase:mah] synonym: "decreased mitotic M phase duration" EXACT [PomBase:mah] synonym: "decreased mitotic M phase duration during vegetative growth" EXACT [PomBase:mah] synonym: "reduced duration of mitotic M phase" EXACT [PomBase:mah] is_a: FYPO:0000607 ! abnormal mitotic M phase progression is_a: FYPO:0001070 ! decreased duration of mitotic cell cycle phase created_by: midori creation_date: 2018-04-06T13:31:07Z [Term] id: FYPO:0006491 name: abnormal chitin synthase activity def: "A molecular function phenotype in which the observed rate of chitin synthase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2018-04-09T13:35:59Z [Term] id: FYPO:0006492 name: abolished chitin synthase activity def: "A molecular function phenotype in which chitin synthase activity is absent." [PomBase:mah] synonym: "chitin synthase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0006491 ! abnormal chitin synthase activity created_by: midori creation_date: 2018-04-09T13:36:10Z [Term] id: FYPO:0006493 name: increased chitin synthase activity def: "A molecular function phenotype in which the observed rate of chitin synthase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0006491 ! abnormal chitin synthase activity created_by: midori creation_date: 2018-04-09T13:36:21Z [Term] id: FYPO:0006494 name: decreased rDNA copy number during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells." [PMID:19205745, PomBase:mah] synonym: "decreased copy number of rDNA repeats" EXACT [PomBase:jh] synonym: "decreased copy number of rDNA repeats during mitotic cell cycle" RELATED [PomBase:jh] synonym: "decreased rDNA copy number during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ribosomal DNA copy number during vegetative growth" EXACT [PomBase:mah] synonym: "shortened rDNA during vegetative growth" RELATED [PomBase:al] is_a: FYPO:0004823 ! abnormal rDNA copy number created_by: midori creation_date: 2018-04-09T15:44:54Z [Term] id: FYPO:0006495 name: increased number of R-loops at tRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal at tRNA genes." [PMID:29622660, PomBase:mah] synonym: "increased level of DNA:RNA hybrids at tRNA genes" EXACT [PomBase:al] synonym: "increased level of RNA-DNA hybrids at tDNA" EXACT [PomBase:mah] synonym: "increased level of RNA-DNA hybrids at tRNA genes" EXACT [] synonym: "increased level of RNA-DNA hybrids at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of RNA-DNA hybrids at tRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA-DNA hybrid level at tRNA genes" EXACT [PomBase:mah] is_a: FYPO:0007901 ! increased number of R-loops created_by: midori creation_date: 2018-04-13T11:22:54Z [Term] id: FYPO:0006496 name: normal plasma membrane phosphatidylserine distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of phosphatidylserine in the plasma membrane is normal (i.e. indistinguishable from wild type)." [PMID:27852900, PomBase:mah] synonym: "normal plasma membrane phosphatidylserine distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal plasma membrane phosphatidylserine distribution during vegetative growth" EXACT [PomBase:mah] synonym: "normal plasma membrane PS distribution" EXACT [PomBase:mah] is_a: FYPO:0006546 ! normal membrane lipid distribution created_by: midori creation_date: 2018-04-16T16:05:30Z [Term] id: FYPO:0006497 name: abnormal plasma membrane phosphatidylserine distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of phosphatidylserine in the plasma membrane is abnormal." [PMID:27852900, PomBase:mah] synonym: "abnormal plasma membrane phosphatidylserine distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal plasma membrane phosphatidylserine distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal plasma membrane PS distribution" EXACT [PomBase:mah] is_a: FYPO:0006545 ! abnormal membrane lipid distribution created_by: midori creation_date: 2018-04-16T16:07:16Z [Term] id: FYPO:0006498 name: increased protein phosphorylation during cellular response to UV def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to ultraviolet light." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to UV during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to UV during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2018-04-18T11:20:17Z [Term] id: FYPO:0006499 name: abnormal cell wall disassembly at cell fusion site def: "A cellular process phenotype in which disassembly of the cell wall at the site of cell-cell fusion during mating is abnormal." [PomBase:mah] synonym: "abnormal cell wall disassembly at cell fusion site during conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "abnormal cell wall disassembly at cell fusion site during mating" EXACT [PomBase:mah] synonym: "abnormal cell wall disassembly at cell-cell fusion focus" EXACT [PomBase:al] synonym: "abnormal cell wall disassembly at cell-cell fusion site" EXACT [PomBase:mah] synonym: "abnormal cell wall disassembly during mating" EXACT [PomBase:mah] synonym: "abnormal fungal-type cell wall disassembly at cell fusion site" EXACT [GO:0071853] synonym: "abnormal fungal-type cell wall disassembly involved in conjugation with cellular fusion" EXACT [GO:1904541] is_a: FYPO:0000031 ! abnormal mating created_by: midori creation_date: 2018-04-18T11:28:29Z [Term] id: FYPO:0006500 name: premature cell wall disassembly at cell fusion site def: "A cellular process phenotype in which disassembly of the cell wall at the site of cell-cell fusion during mating begins earlier than normal, e.g. before pairing with a partner cell. Premature cell wall breakdown often results in cell lysis." [PMID:29453312, PomBase:mah] synonym: "advanced cell wall disassembly at cell fusion site" EXACT [PomBase:mah] synonym: "premature cell wall disassembly at cell fusion site during conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "premature cell wall disassembly at cell fusion site during mating" EXACT [PomBase:mah] synonym: "premature cell wall disassembly at cell-cell fusion focus" EXACT [PomBase:al] synonym: "premature cell wall disassembly at cell-cell fusion site" EXACT [PomBase:mah] synonym: "premature fungal-type cell wall disassembly at cell fusion site" EXACT [GO:0071853] synonym: "premature fungal-type cell wall disassembly involved in conjugation with cellular fusion" EXACT [GO:1904541] is_a: FYPO:0006499 ! abnormal cell wall disassembly at cell fusion site created_by: midori creation_date: 2018-04-18T11:36:26Z [Term] id: FYPO:0006501 name: premature actin fusion focus assembly def: "A cellular process phenotype in which actin fusion focus assembly begins earlier than normal. An actin fusion focus normally forms during mating at the site where the two cells will fuse." [PMID:29453312, PomBase:mah] synonym: "advanced actin fusion focus assembly" EXACT [PomBase:mah] synonym: "premature actin fusion focus formation" EXACT [PomBase:mah] is_a: FYPO:0006108 ! abnormal actin fusion focus assembly created_by: midori creation_date: 2018-04-18T11:43:05Z [Term] id: FYPO:0006502 name: abolished protein localization to cell cortex of cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell cortex of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to cell cortex of cell tip abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000930 ! abolished protein localization to cell cortex during vegetative growth created_by: midori creation_date: 2018-04-18T11:44:31Z [Term] id: FYPO:0006503 name: abnormal protein localization to actin fusion focus def: "A cell phenotype in which the localization of a protein to the actin fusion focus is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with heterochromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actin fusion focus" EXACT [PomBase:mah] is_a: FYPO:0005989 ! abnormal protein localization during mating created_by: midori creation_date: 2018-04-18T13:28:06Z [Term] id: FYPO:0006504 name: multiple shmoo formation def: "A cellular process phenotype in which a cell forms two or more shmoos, usually in succession, without fusing with a partner cell. Cell fusion may or may not subsequently occur." [PMID:29453312, PomBase:mah] synonym: "formation of multiple mating projections" EXACT [PomBase:mah] synonym: "formation of multiple shmoos" EXACT [PomBase:mah] synonym: "multiple mating projection assembly" EXACT [PomBase:mah] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2018-04-18T13:29:07Z [Term] id: FYPO:0006505 name: abolished protein localization to shmoo tip def: "A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to shmoo tip" EXACT [PomBase:mah] synonym: "abolished protein localization to mating projection tip" EXACT [PomBase:mah] synonym: "protein localization to shmoo tip abolished" EXACT [PomBase:mah] is_a: FYPO:0004802 ! abnormal protein localization to shmoo tip created_by: midori creation_date: 2018-04-18T13:31:44Z [Term] id: FYPO:0006506 name: normal RNA level during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during mitotic G1 phase" NARROW [PomBase:mah] synonym: "normal RNA accumulation during mitotic G1 phase" RELATED [PomBase:mah] synonym: "normal RNA level during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal transcript level during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2018-04-18T13:51:15Z [Term] id: FYPO:0006507 name: increased subtelomeric DNA amplification during G0 def: "A cell phenotype in which duplication of DNA sequences in the subtelomeric region occur more frequently than in wild type cells during G0 phase." [PMID:29167439, PomBase:mah] synonym: "increased occurrence of subtelomeric DNA amplification during G0" EXACT [PomBase:mah] synonym: "increased subtelomeric amplification during G0" EXACT [PomBase:vw] synonym: "increased subtelomeric DNA amplification during cell quiescence" EXACT [PomBase:mah] synonym: "increased subtelomeric DNA amplification during quiescence" EXACT [PomBase:mah] synonym: "increased subtelomeric DNA sequence duplication during G0" EXACT [PomBase:mah] is_a: FYPO:0001740 ! increased gross chromosomal rearrangement created_by: midori creation_date: 2018-04-25T13:24:33Z [Term] id: FYPO:0006508 name: abnormal telomere morphology def: "A physical cellular phenotype in which the size, shape, or structure of the telomere is abnormal." [PomBase:mah] comment: Note that an abnormal telomere organization process may, but does not necessarily, result in abnormal telomere morphology. is_a: FYPO:0000287 ! abnormal subcellular component relationship: RO:0002353 FYPO:0007415 ! abnormal telomere maintenance created_by: midori creation_date: 2018-04-25T13:31:56Z [Term] id: FYPO:0006509 name: abnormal telomere length def: "A physical cellular phenotype in which telomere length is abnormal." [PomBase:mah] comment: Note that an abnormal telomere organization process may, but does not necessarily, result in abnormal telomere morphology. is_a: FYPO:0006508 ! abnormal telomere morphology created_by: midori creation_date: 2018-04-25T13:34:47Z [Term] id: FYPO:0006510 name: abnormal telomere structure def: "A physical cellular phenotype in which chromosome structure is abnormal at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region." [PomBase:mah] comment: Note that an abnormal telomere organization process may, but does not necessarily, result in abnormal telomere morphology. synonym: "abnormal chromosome structure at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal telomere structure during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal telomeric region structure during vegetative growth" EXACT [GO:0000781, PomBase:mah] is_a: FYPO:0006508 ! abnormal telomere morphology created_by: midori creation_date: 2018-04-25T13:35:49Z [Term] id: FYPO:0006511 name: shortened telomeres during G0 def: "A physical cellular phenotype in which cells form telomeres that are shorter than normal during G0 phase. Normally, telomere length is stable in G0, whereas telomere sequences can be lost in mutants." [PMID:29167439, PomBase:mah] synonym: "decreased telomere length during G0" RELATED [PomBase:mah] synonym: "loss of telomeric sequence during G0" EXACT [PomBase:vw] synonym: "loss of telomeric sequence during quiescence" EXACT [PomBase:vw] synonym: "reduced telomere length during G0" EXACT [PomBase:mah] synonym: "short telomeres during G0" EXACT [PomBase:mah] synonym: "shortened telomeres during cell quiescence" EXACT [GO:0044838, PomBase:mah] synonym: "shortened telomeres during quiescence" EXACT [PomBase:mah] is_a: FYPO:0006509 ! abnormal telomere length is_a: FYPO:0007413 ! abnormal telomere morphology during G0 created_by: midori creation_date: 2018-04-25T13:45:31Z [Term] id: FYPO:0006512 name: normal telomere morphology def: "A physical cellular phenotype in which the size, shape, or structure of the telomere is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2018-04-25T14:01:26Z [Term] id: FYPO:0006513 name: normal telomere morphology during vegetative growth def: "A physical cellular phenotype in which the size, shape, or structure of the telomere is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal telomere morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth is_a: FYPO:0006512 ! normal telomere morphology created_by: midori creation_date: 2018-04-25T14:01:33Z [Term] id: FYPO:0006514 name: normal telomere structure def: "A physical cellular phenotype in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region." [PomBase:mah] synonym: "normal chromosome structure at telomere" EXACT [PomBase:mah] synonym: "normal chromosome structure at telomeric region" EXACT [GO:0000781, PomBase:mah] synonym: "normal telomeric region structure" EXACT [GO:0000781, PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2018-04-25T14:03:38Z [Term] id: FYPO:0006515 name: normal telomere length def: "A physical cellular phenotype in which telomere length is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2018-04-25T14:08:46Z [Term] id: FYPO:0006516 name: normal telomere length during G0 def: "A physical cellular phenotype in which telomere length is normal (i.e. indistinguishable from wild type) during G0 phase." [PMID:29167439, PomBase:mah] synonym: "normal telomere length during cell quiescence" EXACT [GO:0044838, PomBase:mah] synonym: "normal telomere length during quiescence" EXACT [PomBase:mah] is_a: FYPO:0006515 ! normal telomere length created_by: midori creation_date: 2018-04-25T14:11:20Z [Term] id: FYPO:0006517 name: normal telomere structure during G0 def: "A physical cellular phenotype in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions during G0 phase. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region." [PMID:29167439, PomBase:mah] synonym: "normal chromosome structure at telomere during G0" EXACT [PomBase:mah] synonym: "normal chromosome structure at telomeric region during G0" EXACT [GO:0000781, PomBase:mah] synonym: "normal telomere structure during cell quiescence" EXACT [GO:0044838, PomBase:mah] synonym: "normal telomere structure during quiescence" EXACT [PomBase:mah] synonym: "normal telomeric region structure during G0" EXACT [GO:0000781, PomBase:mah] is_a: FYPO:0006514 ! normal telomere structure created_by: midori creation_date: 2018-04-25T14:13:20Z [Term] id: FYPO:0006518 name: loss of viability in G0 def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering G0 phase." [PMID:29167439, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under nitrogen-depleted conditions until cells enter G0, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "loss of viability in cell quiescence" EXACT [GO:0044838, PomBase:mah] synonym: "loss of viability in quiescence" EXACT [PomBase:mah] is_a: FYPO:0001178 ! loss of viability upon nitrogen starvation created_by: midori creation_date: 2018-04-25T14:18:53Z [Term] id: FYPO:0006519 name: decreased protein degradation during mitotic G1 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during G1 phase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown during mitotic G1 phase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during mitotic G1 phase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during mitotic G1 phase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during G1 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein degradation during mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein degradation during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000846 ! decreased protein degradation during vegetative growth created_by: midori creation_date: 2018-04-25T14:35:03Z [Term] id: FYPO:0006520 name: increased cytoplasmic translation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cytoplasmic translation is increased." [PomBase:mah] comment: Note that this term should be used only when an experiment measures the initiation of protein synthesis directly, e.g. by ribosome profiling. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "increased cytoplasmic translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cytoplasmic translation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003124 ! abnormal cytoplasmic translation created_by: midori creation_date: 2018-04-25T14:58:43Z [Term] id: FYPO:0006521 name: abnormal mitotic sister chromatid cohesion def: "A cellular process phenotype in which mitotic sister chromatid cohesion is abnormal. Mitotic sister chromatid cohesion is the process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle." [GO:0007064, PomBase:mah] synonym: "abnormal mitotic chromosome cohesion" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0002737 ! abnormal mitotic cell cycle process created_by: midori creation_date: 2018-04-25T15:02:09Z [Term] id: FYPO:0006522 name: loss of viability following cell cycle arrest at mitotic G2/M phase transition def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after arrest at the mitotic G2/M phase transition of the mitotic cell cycle." [PMID:11598020, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under conditions that arrest at the G2/M phase transition (e.g. restrictive temperature for a cdc mutant), and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "decreased viability following cell cycle arrest in mitotic G2 phase" EXACT [PomBase:mah] synonym: "loss of cell population viability following cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "loss of viability following mitotic G2/M arrest" EXACT [PomBase:mah] synonym: "loss of viability of mitotic G2-arrested cells" RELATED [PomBase:vw] synonym: "reduced viability following cell cycle arrest at mitotic G2/M phase transition" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2018-04-25T15:17:55Z [Term] id: FYPO:0006523 name: loss of viability in stationary phase following entry from mitotic G2 phase def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase following arrest at the mitotic G2/M phase transition of the mitotic cell cycle." [PMID:11598020, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under conditions that induce stationary phase entry from G2 phase (e.g. minimal medium lacking either glucose or sulfate), and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "decreased viability in stationary phase following entry from mitotic G2 phase" EXACT [PomBase:mah] synonym: "loss of cell population viability in stationary phase following entry from mitotic G2 phase" EXACT [PomBase:mah] synonym: "loss of viability following mitotic G2 arrest and stationary phase entry" EXACT [PomBase:mah] synonym: "loss of viability in stationary phase following entry from mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "loss of viability of following entry into stationary phase from mitotic G2 phase" EXACT [PomBase:mah] synonym: "reduced viability in stationary phase following entry from mitotic G2 phase" RELATED [PomBase:mah] is_a: FYPO:0000245 ! loss of viability in stationary phase is_a: FYPO:0006522 ! loss of viability following cell cycle arrest at mitotic G2/M phase transition created_by: midori creation_date: 2018-04-25T15:20:18Z [Term] id: FYPO:0006524 name: premature sister kinetochore separation during mitotic G2 phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which sister kinetochores separate during G2 phase of the mitotic cell cycle." [PMID:11598020, PomBase:mah] synonym: "premature sister kinetochore separation during G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "premature sister kinetochore separation during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "split kinetochores during mitotic G2 phase" RELATED [PomBase:vw] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2018-05-01T13:38:06Z [Term] id: FYPO:0006525 name: premature sister kinetochore separation during stationary phase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which sister kinetochores of a replicated chromosome separate prematurely when the population in which the cell is found is in stationary phase." [PMID:11598020, PomBase:mah] synonym: "split kinetochores during stationary phase" RELATED [PomBase:vw] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2018-05-01T13:38:14Z [Term] id: FYPO:0006526 name: abnormal meiosis II def: "A cellular process phenotype in which the second meiotic nuclear division is abnormal." [PomBase:mah] synonym: "abnormal second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2018-05-01T13:50:47Z [Term] id: FYPO:0006527 name: decreased proteolysis def: "A cellular process phenotype in which the occurrence of hydrolysis of peptide bonds within a protein is decreased. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased peptidolysis" EXACT [PomBase:mah] synonym: "decreased protein cleavage" RELATED [PomBase:mah] synonym: "reduced proteolysis" EXACT [PomBase:mah] is_a: FYPO:0002498 ! decreased protein modification is_a: FYPO:0005376 ! abnormal proteolysis created_by: midori creation_date: 2018-05-01T14:01:18Z [Term] id: FYPO:0006528 name: decreased proteolysis during meiotic cell cycle def: "A cellular process phenotype in which the occurrence of hydrolysis of peptide bonds within a protein is decreased during the meiotic cell cycle. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased peptidolysis during meiotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein cleavage during meiotic cell cycle" RELATED [PomBase:mah] synonym: "reduced proteolysis during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0006527 ! decreased proteolysis created_by: midori creation_date: 2018-05-01T14:02:21Z [Term] id: FYPO:0006529 name: abnormal protein localization to centromere during meiotic cell cycle def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is abnormal during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to centromere during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal protein localisation to chromosome, centromeric region during meiotic cell cycle" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centric region during meiotic cell cycle" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centromeric region during meiotic cell cycle" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0005597 ! abnormal protein localization to centromere created_by: midori creation_date: 2018-05-01T14:08:18Z [Term] id: FYPO:0006530 name: abolished protein localization to centromere during meiotic prophase II def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is abolished during prophase of the second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to centromere during meiotic prophase II" EXACT [PomBase:mah] synonym: "abolished protein localisation to centromere during prophase II" EXACT [PomBase:mah] synonym: "abolished protein localization to chromosome, centric region during meiotic prophase II" EXACT [GO:0071459, PomBase:mah] synonym: "abolished protein localization to chromosome, centromeric region during meiotic prophase II" EXACT [GO:0071459, PomBase:mah] synonym: "protein localization to centromere abolished during meiotic prophase II" EXACT [PomBase:mah] is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle is_a: FYPO:0006529 ! abnormal protein localization to centromere during meiotic cell cycle created_by: midori creation_date: 2018-05-01T14:12:42Z [Term] id: FYPO:0006531 name: delayed onset of protein degradation during meiosis def: "A cellular process phenotype which protein degradation begins later than normal during one or both meiotic nuclear divisions." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein breakdown during meiosis" EXACT [GO:0030163] synonym: "delayed onset of protein catabolic process during meiosis" EXACT [GO:0030163] synonym: "delayed onset of protein catabolism during meiosis" EXACT [GO:0030163, PomBase:mah] synonym: "delayed onset of protein degradation during meiotic nuclear division" EXACT [PomBase:mah] synonym: "delayed protein degradation during meiosis" EXACT [PomBase:mah] is_a: FYPO:0002275 ! abnormal protein degradation created_by: midori creation_date: 2018-05-01T14:19:37Z [Term] id: FYPO:0006532 name: normal protein localization to centromere during meiotic prophase II def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is normal (i.e. indistinguishable from wild type) during prophase of the second meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to centromere during meiotic prophase II" EXACT [PomBase:mah] synonym: "normal protein localisation to centromere during prophase II" EXACT [PomBase:mah] synonym: "normal protein localization to chromosome, centric region during meiotic prophase II" EXACT [GO:0071459, PomBase:mah] synonym: "normal protein localization to chromosome, centromeric region during prophase II" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0003790 ! normal protein localization during meiosis is_a: FYPO:0006529 ! abnormal protein localization to centromere during meiotic cell cycle created_by: midori creation_date: 2018-05-01T14:23:06Z [Term] id: FYPO:0006533 name: abnormal protein localization to cell periphery def: "A cell phenotype in which the localization of a protein to the cell periphery is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell periphery and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell periphery" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2018-05-01T14:31:41Z [Term] id: FYPO:0006534 name: abolished protein localization to cell periphery during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the cell periphery does not occur when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell periphery during nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to cell periphery during nitrogen depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to cell periphery during nitrogen deprivation" EXACT [PomBase:mah] synonym: "protein absent from cell periphery during nitrogen starvation" RELATED [PomBase:mah] synonym: "protein localization to cell periphery abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0006533 ! abnormal protein localization to cell periphery created_by: midori creation_date: 2018-05-01T14:37:54Z [Term] id: FYPO:0006535 name: increased protein localization to cell periphery during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the cell periphery is increased when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell periphery during nitrogen starvation" EXACT [PomBase:mah] synonym: "increased protein localization to cell periphery during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased protein localization to cell periphery during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0006533 ! abnormal protein localization to cell periphery created_by: midori creation_date: 2018-05-01T14:51:23Z [Term] id: FYPO:0006536 name: increased protein localization to cell periphery during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell periphery during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to cell periphery during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0005570 ! abnormal protein localization to cell periphery during vegetative growth created_by: midori creation_date: 2018-05-01T14:42:04Z [Term] id: FYPO:0006537 name: loss of viability following cellular response to pheromone def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to a pheromone." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown in the presence of hydroxyurea, and then the number of cells viable enough to form a colony upon hydroxyurea removal is measured and compared to wild type. synonym: "decreased viability following cellular response to pheromone" EXACT [PomBase:mah] synonym: "loss of cell population viability following cellular response to pheromone" EXACT [PomBase:mah] synonym: "loss of viability following pheromone exposure" EXACT [PomBase:mah] synonym: "loss of viability upon cellular response to pheromone" EXACT [PomBase:al] synonym: "reduced viability following cellular response to pheromone" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2018-05-01T15:11:19Z [Term] id: FYPO:0006538 name: spheroid cell during cellular response to pheromone def: "A cell morphology phenotype in which a cell is shaped in the form of a spheroid during a cellular response to a pheromone. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "cell morphology, round cells during cellular response to pheromone" RELATED [PomBase:mah] synonym: "cell morphology, rounded cells during cellular response to pheromone" RELATED [PomBase:mah] synonym: "rounded cell during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0001955 ! spheroid cell created_by: midori creation_date: 2018-05-01T15:13:30Z [Term] id: FYPO:0006539 name: multiseptate cell during cellular response to pheromone def: "A cell phenotype in which a cell contains more than one septum during a cellular response to a pheromone." [PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. is_a: FYPO:0004295 ! multiseptate cell created_by: midori creation_date: 2018-05-01T15:25:06Z [Term] id: FYPO:0006540 name: abnormal actin cytoskeleton organization during cellular response to pheromone def: "A cellular process phenotype in which actin cytoskeleton organization is abnormal during a cellular response to pheromone." [GO:0030036, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton' (FYPO:0002398), but note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in a physically abnormal actin cytoskeleton. synonym: "abnormal actin cytoskeleton organisation during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0004803 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2018-05-01T15:29:23Z [Term] id: FYPO:0006541 name: decreased protein level during mating def: "A cell phenotype in which the amount of protein measured in a cell during mating is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during mating" RELATED [PomBase:mah] synonym: "decreased protein level during conjugation with cellular fusion" EXACT [GO:0000747, PomBase:mah] synonym: "reduced protein level during mating" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2018-05-01T15:40:20Z [Term] id: FYPO:0006542 name: increased RNA level during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during mitosis is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during mitosis" NARROW [PomBase:mah] synonym: "increased RNA accumulation during mitosis" RELATED [PomBase:mah] synonym: "increased RNA level during M phase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during mitotic M phase" RELATED [PomBase:mah] synonym: "increased transcript level during mitosis" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2018-05-01T15:56:26Z [Term] id: FYPO:0006543 name: increased protein level during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during metaphase of mitosis is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during mitotic metaphase" RELATED [PomBase:mah] synonym: "increased protein level during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during metaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0004157 ! increased protein level during mitosis created_by: midori creation_date: 2018-05-01T16:03:01Z [Term] id: FYPO:0006544 name: decreased transcription during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during mitosis. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "decreased transcription during cellular response to calcium ion during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased transcription during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription during mitotic nuclear division" EXACT [GO:0140014] synonym: "reduced transcription during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2018-05-02T15:30:45Z [Term] id: FYPO:0006545 name: abnormal membrane lipid distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of one or more lipids in a cellular membrane is abnormal." [GO:0097035, PomBase:mah] synonym: "abnormal membrane lipid distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal membrane lipid distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of membrane lipid distribution" EXACT [GO:0097035, PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2018-05-08T12:12:07Z [Term] id: FYPO:0006546 name: normal membrane lipid distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of one or more lipids in a cellular membrane is normal (i.e. indistinguishable from wild type)." [GO:0097035, PomBase:mah] synonym: "normal membrane lipid distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal membrane lipid distribution during vegetative growth" EXACT [PomBase:mah] synonym: "normal regulation of membrane lipid distribution" EXACT [GO:0097035, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2018-05-08T12:18:19Z [Term] id: FYPO:0006547 name: abnormal plasma membrane phosphatidylserine distribution resulting in decreased concentration at cell tip def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of phosphatidylserine (PS) in the plasma membrane is abnormal such that the PS level is lower than normal at one or both cell tips. Normally, PS shows a polarized distribution with a higher concentration at the cell tips than in the lateral plasma membrane." [PMID:27852900, PomBase:mah] synonym: "abnormal plasma membrane phosphatidylserine distribution resulting in decreased concentration at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal plasma membrane phosphatidylserine distribution resulting in decreased concentration at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal plasma membrane phosphatidylserine distribution resulting in reduced concentration at cell tip" EXACT [PomBase:mah] synonym: "abnormal plasma membrane PS distribution resulting in decreased concentration at cell tip" EXACT [PomBase:mah] synonym: "decreased plasma membrane phosphatidylserine polarity" RELATED [PomBase:vw] synonym: "reduced plasma membrane phosphatidylserine polarity" RELATED [PomBase:vw] is_a: FYPO:0006497 ! abnormal plasma membrane phosphatidylserine distribution created_by: midori creation_date: 2018-05-08T12:23:07Z [Term] id: FYPO:0006548 name: increased gene expression def: "A cellular process phenotype in which gene expression occurs to a greater extent than normal. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected." [PomBase:mah] is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2018-05-08T13:21:14Z [Term] id: FYPO:0006549 name: decreased gene expression def: "A cellular process phenotype in which gene expression occurs to a lower extent than normal. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "reduced gene expression" EXACT [PomBase:mah] is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2018-05-08T13:21:14Z [Term] id: FYPO:0006550 name: decreased gene expression during nitrogen starvation def: "A cellular process phenotype in which gene expression occurs to a lower extent than normal when the cell is subject to nitrogen starvation. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "decreased gene expression during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased gene expression during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced gene expression during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0006549 ! decreased gene expression created_by: midori creation_date: 2018-05-08T13:25:54Z [Term] id: FYPO:0006551 name: abnormal gene expression def: "A cellular process phenotype in which gene expression is abnormal. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected." [GO:0010467, PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2018-05-08T13:26:41Z [Term] id: FYPO:0006552 name: increased protein localization to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cytoplasm" EXACT [PomBase:mah] synonym: "increased protein localization to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to cytoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006098 ! abnormal protein localization to cytoplasm created_by: midori creation_date: 2018-05-08T13:46:57Z [Term] id: FYPO:0006553 name: normal protein localization to nucleus def: "A cell phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization created_by: midori creation_date: 2018-05-08T13:50:21Z [Term] id: FYPO:0006554 name: normal protein localization to nucleus during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0006553 ! normal protein localization to nucleus created_by: midori creation_date: 2018-05-08T13:50:37Z [Term] id: FYPO:0006555 name: abnormal multiple protein binding to DNA def: "A molecular function phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes." [PMID:20924116, PomBase:mah] synonym: "abnormal cooperative DNA binding" RELATED [PomBase:mah] synonym: "abnormal protein-DNA ternary complex formation" NARROW [PomBase:mah] synonym: "abnormal protein-protein interaction on DNA" RELATED [PomBase:mah] synonym: "abnormal ternary complex formation" RELATED [PomBase:mah] synonym: "abolished protein-DNA ternary complex formation" NARROW [PomBase:mah] synonym: "abolished ternary complex formation" RELATED [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2018-05-08T13:56:52Z [Term] id: FYPO:0006556 name: inviable elongated tetranucleate triseptate vegetative cell, single septa between nuclei def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is elongated, has four nuclei and three septa, and the septa are not grouped together, but are located so as to form separate compartments with a single nucleus in each." [PomBase:mah, PomBase:vw] synonym: "inviable elongated multiseptate vegetative cell, with four nuclei and single septa between nuclei" EXACT [PomBase:mah] synonym: "inviable elongated tetranucleate triseptate cell, single septa between nuclei during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated tetranucleate triseptate vegetative cell, single septa between nuclei during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated tetranucleate triseptate vegetative cell, single septa between nuclei" EXACT [PomBase:mah] is_a: FYPO:0001253 ! elongated multinucleate multiseptate vegetative cell, single septa between nuclei is_a: FYPO:0001493 ! inviable elongated multinucleate vegetative cell is_a: FYPO:0001494 ! inviable elongated multiseptate vegetative cell is_a: FYPO:0004044 ! elongated tetranucleate vegetative cell created_by: midori creation_date: 2018-06-05T13:22:46Z [Term] id: FYPO:0006557 name: abolished cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis does not occur." [PomBase:mah] synonym: "abolished cell separation after cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic cytokinetic cell separation" EXACT [PomBase:mah] synonym: "abolished septum digestion after cytokinesis" EXACT [GO:0000920] synonym: "cell separation after cytokinesis abolished" EXACT [PomBase:mah] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: midori creation_date: 2018-06-05T13:44:05Z [Term] id: FYPO:0006558 name: abolished septum disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum disassembly does not occur." [PomBase:mah] synonym: "abolished primary cell septum disassembly" RELATED [GO:0030994] synonym: "abolished primary septum disassembly" EXACT [PomBase:mah] synonym: "abolished septum disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished septum disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "septum disassembly abolished" EXACT [PomBase:mah] is_a: FYPO:0000132 ! abnormal septum disassembly relationship: has_output FYPO:0006557 ! abolished cell separation after cytokinesis created_by: midori creation_date: 2018-06-05T13:45:20Z [Term] id: FYPO:0006559 name: delayed onset of mitotic spindle disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle disassembly begins later than normal." [GO:0051228, PomBase:mah] synonym: "delayed mitotic spindle disassembly" EXACT [PomBase:mah] synonym: "delayed onset of mitotic spindle disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of spindle disassembly during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004621 ! abnormal mitotic spindle disassembly created_by: midori creation_date: 2018-06-05T13:50:44Z [Term] id: FYPO:0006560 name: decreased protein kinase activity during mitotic G1 phase def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the G1 phase of the mitotic cell cycle." [PomBase:mah] synonym: "reduced protein kinase activity during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0003331 ! decreased protein kinase activity during mitotic interphase created_by: midori creation_date: 2018-06-05T14:15:14Z [Term] id: FYPO:0006561 name: normal CDK-cyclin complex binding during mitotic G1 phase def: "A molecular function phenotype in which the binding of one protein to a CDK-cyclin complex is normal (i.e. indistinguishable from wild type) during the G1 phase of the mitotic cell cycle. The protein whose binding to the CDK-cyclin complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." [PMID:8521500, PomBase:mah] comment: This term can be used for any interaction with a protein complex that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal CDK-cyclin complex binding during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal CDK-cyclin complex binding during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal cyclin-CDK complex binding during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0005232 ! normal protein complex binding created_by: midori creation_date: 2018-06-05T14:16:50Z [Term] id: FYPO:0006562 name: increased RNA level during mitotic G2 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during G2 phase of the mitotic cell cycle is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during mitotic G2 phase" NARROW [PomBase:mah] synonym: "increased RNA accumulation during mitotic G2 phase" RELATED [PomBase:mah] synonym: "increased RNA level during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased RNA level during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during mitotic G2 phase" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2018-06-05T14:25:19Z [Term] id: FYPO:0006563 name: abolished MBF complex assembly during mitotic G1 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MBF complex assembly is abolished during G1 phase of the mitotic cell cycle." [PomBase:mah] synonym: "abolished MBF complex assembly during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished MBF complex assembly during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished MBF transcription complex assembly during mitotic G1 phase" EXACT [PomBase:mah] synonym: "MBF complex assembly abolished during mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2018-06-05T14:27:07Z [Term] id: FYPO:0006564 name: sensitive to ethanol in stationary phase def: "A phenotype in which cells show increased sensitivity to ethanol when the cell population is in stationary phase. Cells stop growing (and may die) at a concentration of ethanol that allows wild type cells to grow." [PMID:9372444, PomBase:mah] synonym: "decreased cell population growth during cellular response to ethanol in stationary phase" EXACT [PomBase:mah] synonym: "decreased growth during cellular response to ethanol in stationary phase" EXACT [PomBase:mah] synonym: "hypersensitive to ethanol in stationary phase" EXACT [PomBase:mah] synonym: "sensitive to ethanol during stationary phase" EXACT [PomBase:mah] synonym: "sensitive to ethyl alcohol in stationary phase" EXACT [CHEBI:16236] is_a: FYPO:0008000 ! increased sensitivity to chemical in stationary phase created_by: midori creation_date: 2018-06-08T13:50:44Z [Term] id: FYPO:0006565 name: normal viability upon phosphate starvation def: "A cell population phenotype in which a normal proportion of cells in the population remains viable under conditions of phosphate starvation." [PMID:9372444, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase under phosphate-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "normal cell population viability upon phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2018-06-08T13:58:06Z [Term] id: FYPO:0006566 name: normal viability upon sulfur starvation def: "A cell population phenotype in which a normal proportion of cells in the population remains viable under conditions of sulfur starvation." [PMID:9372444, PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase under sulfur-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "normal cell population viability upon sulfur starvation" EXACT [PomBase:mah] synonym: "normal viability upon sulphur starvation" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2018-06-08T14:01:17Z [Term] id: FYPO:0006567 name: abnormal DNA repair def: "A cellular process phenotype in which DNA repair is abnormal." [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype created_by: midori creation_date: 2018-06-08T14:08:13Z [Term] id: FYPO:0006568 name: abnormal meiotic mismatch repair def: "A cellular process phenotype in which meiotic mismatch repair is abnormal. Meiotic mismatch repair is the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules." [GO:0000710, PomBase:mah] is_a: FYPO:0006567 ! abnormal DNA repair created_by: midori creation_date: 2018-06-08T14:10:51Z [Term] id: FYPO:0006569 name: normal DNA repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA repair is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal DNA repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2018-06-08T14:27:20Z [Term] id: FYPO:0006570 name: normal UV-damage excision repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair is normal (i.e. indistinguishable from wild type). UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [GO:0070914, PomBase:mah] synonym: "normal UV-damage excision repair during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal UV-damage excision repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2018-06-08T14:28:42Z [Term] id: FYPO:0006571 name: increased cyclin-dependent protein kinase activity during cellular response to pheromone def: "A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased during a cellular response to a pheromone." [PMID:9614176, PomBase:mah] is_a: FYPO:0004319 ! increased cyclin-dependent protein kinase activity created_by: midori creation_date: 2018-06-08T14:32:32Z [Term] id: FYPO:0006572 name: abolished protein degradation during cellular response to pheromone def: "A cellular process phenotype in which protein degradation does not occur during a cellular response to a pheromone. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [PMID:9614176, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein breakdown during cellular response to pheromone" EXACT [GO:0030163, PomBase:mah] synonym: "abolished protein catabolic process during cellular response to pheromone" EXACT [GO:0030163, PomBase:mah] synonym: "abolished protein catabolism during cellular response to pheromone" EXACT [GO:0030163, PomBase:mah] synonym: "protein degradation abolished during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0002275 ! abnormal protein degradation created_by: midori creation_date: 2018-06-08T14:39:58Z [Term] id: FYPO:0006573 name: normal protein level during cellular response to pheromone def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to a pheromone is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to pheromone" RELATED [PomBase:mah] is_a: FYPO:0004083 ! normal protein level created_by: midori creation_date: 2018-06-08T14:45:03Z [Term] id: FYPO:0006574 name: normal RNA level during cellular response to pheromone def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to a pheromone is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to pheromone" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to pheromone" RELATED [PomBase:mah] synonym: "normal transcript level during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2018-06-08T14:50:28Z [Term] id: FYPO:0006575 name: abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with otherwise normal S phase def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which abnormal negative regulation of the initiation of mitotic DNA replication results in one or more rounds of rereplication of the entire genome, but takes place during S phases that appear nearly normal apart from occurring without intervening mitoses. Origin usage is normal, rounds of DNA synthesis are correlated with G1/S phase gene expression and cell mass increase, and the genome is replicated evenly." [PMID:19487461, PMID:20736315, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with otherwise normal S phase, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with otherwise normal S phase, during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycling without mitosis" RELATED [PomBase:al, PomBase:jh] is_a: FYPO:0001425 ! abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication created_by: midori creation_date: 2018-06-13T13:41:06Z [Term] id: FYPO:0006576 name: abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with abnormal S phase def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which abnormal negative regulation of the initiation of mitotic DNA replication results in one or more rounds of rereplication of the entire genome, and other features of S phase are abnormal. Rounds of replication are not correlated with G1/S phase gene expression, and origin usage is altered." [PMID:19487461, PMID:20736315, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with abnormal S phase, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with abnormal S phase, during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in continuous DNA synthesis" RELATED [PomBase:al] is_a: FYPO:0001425 ! abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication created_by: midori creation_date: 2018-06-13T13:43:39Z [Term] id: FYPO:0006577 name: increased cellular P(1),P(4)-bis(5'-adenosyl) tetraphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of P(1),P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A) measured in a cell is higher than normal." [PMID:10970777, PomBase:mah] synonym: "increased cellular Ap4A level" EXACT [PMID:10970777] synonym: "increased cellular diadenosine 5',5'''-P1,P4-tetraphosphate level" RELATED [PMID:10970777] synonym: "increased cellular diadenosine tetraphosphate level" RELATED [PomBase:mah] synonym: "increased cellular diadenosyl tetraphosphate level" BROAD [PomBase:mah] synonym: "increased cellular P(1),P(4)-bis(5'-adenosyl) tetraphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular P(1),P(4)-bis(5'-adenosyl) tetraphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased P(1),P(4)-bis(5'-adenosyl) tetraphosphate accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-06-13T14:14:14Z [Term] id: FYPO:0006578 name: normal mitotic G2 DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is normal (i.e. indistinguishable from wild type). The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage." [PomBase:mah] synonym: "normal G2 DNA damage checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G2 DNA damage checkpoint activation" EXACT [PomBase:al] synonym: "normal mitotic G2 DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2018-06-13T14:24:56Z [Term] id: FYPO:0006579 name: sensitive to manganese def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to manganese. Cells stop growing (and may die) at a concentration of manganese ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to manganese" EXACT [PomBase:mah] synonym: "sensitive to manganese during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to manganese during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to manganese ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2018-06-13T14:42:04Z [Term] id: FYPO:0006580 name: resistance to amiodarone def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amiodarone than normal." [PomBase:mah] synonym: "resistance to amiodarone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to amiodarone during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to amiodarone" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2018-06-13T15:06:15Z [Term] id: FYPO:0006581 name: sensitive to fenpropimorph def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fenpropimorph. Cells stop growing (and may die) at a concentration of fenpropimorph that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to fenpropimorph" EXACT [PomBase:mah] synonym: "sensitive to fenpropimorph during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to fenpropimorph during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2018-06-13T15:07:46Z [Term] id: FYPO:0006582 name: decreased bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity def: "A molecular function phenotype in which the observed rate of bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity is decreased." [PomBase:mah] synonym: "reduced bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0004644 ! abnormal bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity created_by: midori creation_date: 2018-06-19T12:38:22Z [Term] id: FYPO:0006583 name: decreased protein localization to nuclear periphery during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is decreased during interphase of the mitotic cell cycle. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane." [GO:0034399, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nuclear periphery during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to nuclear periphery during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nuclear periphery during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein localization to nuclear periphery during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0002339 ! decreased protein localization to nuclear periphery created_by: midori creation_date: 2018-06-19T12:44:56Z [Term] id: FYPO:0006584 name: abnormal protein localization to shmoo tip membrane def: "A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to shmoo tip membrane" EXACT [PomBase:mah] synonym: "abnormal protein localization to mating projection tip membrane" EXACT [PomBase:mah] synonym: "abnormal protein localization to plasma membrane at shmoo tip" EXACT [PomBase:mah] synonym: "abnormal protein localization to shmoo membrane fusion domain" EXACT [PMID:29134248] synonym: "abnormal protein localization to shmoo projection membrane" RELATED [PomBase:al] is_a: FYPO:0004802 ! abnormal protein localization to shmoo tip is_a: FYPO:0004838 ! abnormal protein localization to plasma membrane created_by: midori creation_date: 2018-06-20T11:47:58Z [Term] id: FYPO:0006585 name: abolished protein localization to shmoo tip membrane, with protein mislocalized to endoplasmic reticulum def: "A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abolished, and the protein is present in the endoplasmic reticulum instead." [PMID:29134248, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localization to plasma membrane at shmoo tip, with protein mislocalized to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "abnormal protein localization to shmoo membrane fusion domain, with protein mislocalized to endoplasmic reticulum" EXACT [PMID:29134248] synonym: "abnormal protein localization to shmoo projection membrane, with protein mislocalized to endoplasmic reticulum" RELATED [PomBase:al] synonym: "abolished protein localisation to mating projection tip membrane, with protein mislocalised to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "abolished protein localization to mating projection tip membrane, with protein mislocalized to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "abolished protein localization to shmoo tip membrane, with protein mislocalized to ER" EXACT [PomBase:mah] synonym: "protein localization to shmoo tip membrane abolished, with protein mislocalized to endoplasmic reticulum" RELATED [PomBase:mah] is_a: FYPO:0006505 ! abolished protein localization to shmoo tip is_a: FYPO:0006584 ! abnormal protein localization to shmoo tip membrane is_a: FYPO:0006590 ! protein mislocalized to endoplasmic reticulum relationship: has_part FYPO:0006590 ! protein mislocalized to endoplasmic reticulum created_by: midori creation_date: 2018-06-20T11:51:25Z [Term] id: FYPO:0006586 name: abolished protein localization to shmoo tip membrane, with protein distributed in plasma membrane def: "A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abolished, and the protein is instead detected distributed over a greater area of the plasma membrane than normal." [PMID:29134248, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to mating projection tip membrane, with protein distributed in plasma membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to mating projection tip membrane, with protein distributed in plasma membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to plasma membrane at shmoo tip, with protein distributed in plasma membrane" EXACT [PomBase:mah] synonym: "abolished protein localization to shmoo membrane fusion domain, with protein distributed in plasma membrane" EXACT [PMID:29134248] synonym: "abolished protein localization to shmoo projection membrane, with protein distributed in plasma membrane" RELATED [PomBase:al] synonym: "protein localization to shmoo tip membrane abolished, with protein distributed in plasma membrane" RELATED [PomBase:mah] is_a: FYPO:0006584 ! abnormal protein localization to shmoo tip membrane relationship: has_part FYPO:0006386 ! protein abnormally dispersed at shmoo tip created_by: midori creation_date: 2018-06-20T11:55:21Z [Term] id: FYPO:0006587 name: decreased protein localization to shmoo tip membrane def: "A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is decreased." [PMID:29134248, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to shmoo tip membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to mating projection tip membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to plasma membrane at shmoo tip" EXACT [PomBase:mah] synonym: "decreased protein localization to shmoo membrane fusion domain" EXACT [PMID:29134248] synonym: "decreased protein localization to shmoo projection membrane" RELATED [PomBase:al] synonym: "reduced protein localization to shmoo tip membrane" EXACT [PomBase:mah] is_a: FYPO:0006584 ! abnormal protein localization to shmoo tip membrane created_by: midori creation_date: 2018-06-20T12:00:21Z [Term] id: FYPO:0006588 name: decreased protein localization to shmoo tip membrane, with protein mislocalized to endoplasmic reticulum def: "A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is decreased, and some of the protein is present in the endoplasmic reticulum instead." [PMID:29134248, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mating projection tip membrane, with protein mislocalised to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "decreased protein localization to mating projection tip membrane, with protein mislocalized to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "decreased protein localization to plasma membrane at shmoo tip, with protein mislocalized to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "decreased protein localization to shmoo membrane fusion domain, with protein mislocalized to endoplasmic reticulum" EXACT [PMID:29134248] synonym: "decreased protein localization to shmoo projection membrane, with protein mislocalized to endoplasmic reticulum" RELATED [PomBase:al] synonym: "decreased protein localization to shmoo tip membrane, with protein mislocalized to ER" EXACT [PomBase:mah] synonym: "reduced protein localization to shmoo tip membrane, with protein mislocalized to endoplasmic reticulum" RELATED [PomBase:mah] is_a: FYPO:0006587 ! decreased protein localization to shmoo tip membrane is_a: FYPO:0006590 ! protein mislocalized to endoplasmic reticulum created_by: midori creation_date: 2018-06-20T12:05:46Z [Term] id: FYPO:0006589 name: decreased protein localization to shmoo tip membrane, with protein distributed in plasma membrane def: "A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is decreased, and some of the protein is instead detected distributed over a greater area of the plasma membrane than normal." [PMID:29134248, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mating projection tip membrane, with protein distributed in plasma membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to mating projection tip membrane, with protein distributed in plasma membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to plasma membrane at shmoo tip, with protein distributed in plasma membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to shmoo membrane fusion domain, with protein distributed in plasma membrane" EXACT [PMID:29134248] synonym: "decreased protein localization to shmoo projection membrane, with protein distributed in plasma membrane" RELATED [PomBase:al] synonym: "reduced protein localization to shmoo tip membrane, with protein distributed in plasma membrane" RELATED [PomBase:mah] is_a: FYPO:0006587 ! decreased protein localization to shmoo tip membrane created_by: midori creation_date: 2018-06-20T12:07:45Z [Term] id: FYPO:0006590 name: protein mislocalized to endoplasmic reticulum def: "A cell phenotype in which a protein that is not normally found in the endoplasmic reticulum is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the ER in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to endoplasmic reticulum" EXACT [PomBase:vw] synonym: "protein mislocalised to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "protein mislocalized to ER" EXACT [PomBase:mah] is_a: FYPO:0003452 ! mislocalized protein created_by: midori creation_date: 2018-06-20T14:07:57Z [Term] id: FYPO:0006591 name: increased DNA damage during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured in a cell during S phase of the mitotic cell cycle is greater than normal. The number, extent, or both of damage sites may be increased." [PomBase:mah] synonym: "increased DNA damage during S phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased DNA damage during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased number of DNA lesions during mitotic S phase" RELATED [PomBase:al] is_a: FYPO:0003547 ! increased DNA damage during vegetative growth created_by: midori creation_date: 2018-06-25T12:03:37Z [Term] id: FYPO:0006592 name: monopolar mitotic spindle nucleated from old spindle pole body def: "A physical cellular phenotype in which the mitotic spindle forms with microtubules emanating from only one pole, nucleated from the old spindle pole body." [PMID:19942852, PomBase:mah] synonym: "monopolar mitotic spindle nucleated from old SPB" EXACT [PomBase:mah] synonym: "monopolar mitotic spindle nucleated from old spindle pole body during mitotic cell cycle" EXACT [PomBase:mah] synonym: "monopolar mitotic spindle nucleated from old spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000276 ! monopolar mitotic spindle relationship: RO:0002353 FYPO:0007422 ! abolished mitotic spindle microtubule nucleation from spindle pole body created_by: midori creation_date: 2018-06-25T12:07:05Z [Term] id: FYPO:0006593 name: decreased mitotic spindle microtubule nucleation from spindle pole body def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of spindle microtubules from the spindle pole body (SPB) occurs to a lesser extent than normal." [PMID:19942852, PomBase:mah] synonym: "decreased microtubule nucleation from spindle pole body during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased mitotic spindle microtubule nucleation by spindle pole body" EXACT [GO:0051417] synonym: "decreased mitotic spindle microtubule nucleation from SPB" EXACT [PomBase:mah] synonym: "decreased mitotic spindle microtubule nucleation from spindle pole body during mitotic M phase" EXACT [PomBase:vw] synonym: "decreased mitotic spindle microtubule nucleation from spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spindle microtubule nucleation from mitotic SPB" EXACT [PomBase:mah] synonym: "decreased spindle microtubule nucleation from mitotic spindle pole body" EXACT [PomBase:mah] synonym: "reduced mitotic spindle microtubule nucleation from spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0006336 ! decreased mitotic microtubule nucleation created_by: midori creation_date: 2018-06-25T13:44:31Z [Term] id: FYPO:0006594 name: normal gamma-tubulin complex localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which localization of the gamma-tubulin complex to the spindle pole body is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal gamma-tubulin complex localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "normal gamma-tubulin complex localization to mitotic SPB" EXACT [PomBase:mah] synonym: "normal gamma-tubulin complex localization to mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "normal gamma-tubulin complex localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2018-06-25T13:49:24Z [Term] id: FYPO:0006596 name: increased level of flocculin gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs transcribed from genes encoding flocculins measured in a cell is higher than normal (i.e. higher than observed in wild-type cells)." [PMID:29878109, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased flocculin gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of flocculin gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of flocculin gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of flocculin gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2018-06-25T14:19:53Z [Term] id: FYPO:0006597 name: increased level of cell wall organization gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell wall organization RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Cell wall organization RNAs are transcribed from genes whose products are involved in assembly, alteration, or disassembly of the cell wall." [PMID:29878109, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased cell wall organization gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of cell wall organization gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of cell wall organization gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of cell wall organization gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased level of cell wall remodeling gene mRNA during vegetative growth" EXACT [PMID:29878109] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2018-06-25T14:22:14Z [Term] id: FYPO:0006598 name: decreased histone H3-T3 phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of threonine at position 3 of histone H3 is decreased." [PomBase:mah] synonym: "decreased histone H3 phosphorylation at T3 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-pT3 during vegetative growth" RELATED [PomBase:vw] synonym: "decreased histone H3-T3 phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3T3 phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-T3 phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: midori creation_date: 2018-06-27T14:08:16Z [Term] id: FYPO:0006599 name: decreased protein localization to centromeric chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromeric chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to centromeric chromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000450 ! decreased protein localization to centromere during vegetative growth is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth is_a: FYPO:0005306 ! abnormal protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2018-06-27T14:12:08Z [Term] id: FYPO:0006600 name: decreased protein localization to centromeric chromatin during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased during metaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromeric chromatin during mitotic metaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to centromeric chromatin during metaphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to centromeric chromatin during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0003002 ! decreased protein localization to centromere during mitotic metaphase is_a: FYPO:0006599 ! decreased protein localization to centromeric chromatin during vegetative growth created_by: midori creation_date: 2018-06-27T14:13:46Z [Term] id: FYPO:0006601 name: normal protein localization to centromeric chromatin during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is normal (i.e. indistinguishable from wild type during metaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to centromeric chromatin during mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to centromeric chromatin during metaphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at centromere during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0005072 ! normal protein localization to centromeric chromatin created_by: midori creation_date: 2018-06-27T14:15:16Z [Term] id: FYPO:0006602 name: decreased replication fork arrest at MPS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the MPS1 barrier in the mating-type locus occurs to a lower extent than normal." [PMID:26201080, PomBase:mah] synonym: "decreased replication fork arrest at MPS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork arrest at MPS1 barrier during vegetative growth" EXACT [PomBase:mah] synonym: "decreased replication fork arrest at MPS1 element" EXACT [PomBase:mah] synonym: "reduced replication fork arrest at MPS1 barrier" EXACT [PomBase:mah] is_a: FYPO:0003085 ! decreased replication fork arrest at mating-type locus created_by: midori creation_date: 2018-06-27T14:18:25Z [Term] id: FYPO:0006603 name: decreased replication fork arrest at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the RTS1 barrier (normally located in the mating-type region) occurs to a lower extent than normal." [PMID:26201080, PomBase:mah] synonym: "decreased replication fork arrest at RTS1 barrier during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork arrest at RTS1 barrier during vegetative growth" EXACT [PomBase:mah] synonym: "decreased replication fork arrest at RTS1 element" EXACT [PomBase:mah] synonym: "reduced replication fork arrest at RTS1 barrier" EXACT [PomBase:mah] is_a: FYPO:0003088 ! abnormal replication fork arrest created_by: midori creation_date: 2018-06-27T14:21:45Z [Term] id: FYPO:0006604 name: decreased replication fork arrest at tRNA locus def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic tRNA transcription unit occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased replication fork arrest at tRNA genes" EXACT [PomBase:mah] synonym: "decreased replication fork arrest at tRNA locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork arrest at tRNA locus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced replication fork arrest at tRNA locus" EXACT [PomBase:mah] is_a: FYPO:0003088 ! abnormal replication fork arrest created_by: midori creation_date: 2018-06-27T14:36:30Z [Term] id: FYPO:0006605 name: normal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate def: "A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type) when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage." [PomBase:mah] synonym: "normal intra-S phase DNA damage checkpoint during cellular response to methyl methanesulfonate" EXACT [GO:0031573] synonym: "normal mitotic S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint activation during cellular response to methyl methanesulfonate" EXACT [PomBase:al] synonym: "normal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal S-phase DNA damage checkpoint during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0003530 ! normal S-phase DNA damage checkpoint is_a: FYPO:0005373 ! normal mitotic cell cycle regulation during cellular response to methyl methanesulfonate created_by: midori creation_date: 2018-06-27T14:41:48Z [Term] id: FYPO:0006606 name: abnormal dynamic protein localization pattern def: "A cell phenotype in which a protein that is normally dynamically localized to a specific place in the cell shows an abnormal temporal pattern of localization. For example, a protein may move to or from the location more or less frequently than normal." [PomBase:mah] subset: qc_do_not_manually_annotate synonym: "abnormal dynamic pattern of protein localization" EXACT [PomBase:mah] synonym: "abnormal dynamic protein localisation pattern" EXACT [PomBase:mah] synonym: "abnormal protein exchange" EXACT [PomBase:mlr] synonym: "abnormal protein turnover" EXACT [PomBase:mlr] synonym: "abnormal temporal protein localization pattern" RELATED [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2018-07-04T13:27:38Z [Term] id: FYPO:0006607 name: abnormal intermittent protein localization to Cdr2 medial cortical node complex def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex shows an abnormal pattern of localization to the complex over time." [PMID:29514920, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal bursts of intermittent protein localization to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "abnormal intermittent protein localization to Cdr2 medial cortical node complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal intermittent protein localization to Cdr2 medial cortical node complex during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal pattern of intermittent protein localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] synonym: "abnormal pattern of protein visits to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "abnormal protein localization bursts to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "abnormal transient protein localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2018-07-04T13:36:02Z [Term] id: FYPO:0006608 name: intermittent protein localization to Cdr2 medial cortical node complex decoupled from cell size def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex shows a pattern of localization to the complex over time that is not correlated with cell size as normal." [PMID:29514920, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "bursts of intermittent protein localization to Cdr2 medial cortical node complex decoupled from cell size" RELATED [PomBase:mah] synonym: "intermittent protein localization to Cdr2 medial cortical node complex decoupled from cell size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "intermittent protein localization to Cdr2 medial cortical node complex decoupled from cell size during vegetative growth" EXACT [PomBase:mah] synonym: "loss of correlation between intermittent protein localization to Cdr2 medial cortical node complex and cell size" EXACT [PomBase:mah] synonym: "pattern of protein visits to Cdr2 medial cortical node complex decoupled from cell size" RELATED [PomBase:mah] synonym: "protein localization bursts to Cdr2 medial cortical node complex decoupled from cell size" RELATED [PomBase:mah] synonym: "transient protein localization to Cdr2 medial cortical node complex decoupled from cell size" EXACT [PomBase:mah] is_a: FYPO:0006607 ! abnormal intermittent protein localization to Cdr2 medial cortical node complex created_by: midori creation_date: 2018-07-04T13:40:05Z [Term] id: FYPO:0006609 name: decreased protein dwell time during intermittent localization to Cdr2 medial cortical node complex def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex is associated with the complex for periods of shorter duration than normal." [PMID:29514920, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased duration of bursts of intermittent protein localization to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "decreased duration of protein localization bursts to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "decreased duration of protein visits to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "decreased protein dwell time during intermittent localization to Cdr2 medial cortical node complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein dwell time during intermittent localization to Cdr2 medial cortical node complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein dwell time during transient localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] synonym: "reduced protein dwell time during intermittent localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] is_a: FYPO:0006607 ! abnormal intermittent protein localization to Cdr2 medial cortical node complex created_by: midori creation_date: 2018-07-04T13:48:37Z [Term] id: FYPO:0006610 name: increased protein dwell time during intermittent localization to Cdr2 medial cortical node complex def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex is associated with the complex for periods of longer duration than normal." [PMID:29514920, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of bursts of intermittent protein localization to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "increased duration of protein localization bursts to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "increased duration of protein visits to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "increased protein dwell time during intermittent localization to Cdr2 medial cortical node complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein dwell time during intermittent localization to Cdr2 medial cortical node complex during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein dwell time during transient localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] is_a: FYPO:0006607 ! abnormal intermittent protein localization to Cdr2 medial cortical node complex created_by: midori creation_date: 2018-07-04T14:11:33Z [Term] id: FYPO:0006611 name: decreased frequency of protein localization to Cdr2 medial cortical node complex during intermittent localization to Cdr2 medial cortical node complex def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex is associated with the complex less frequently than normal." [PMID:29514920, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased frequency of bursts of intermittent protein localization to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "decreased frequency of protein localization bursts to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "decreased frequency of protein localization to Cdr2 medial cortical node complex during intermittent localization to Cdr2 medial cortical node complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased frequency of protein localization to Cdr2 medial cortical node complex during intermittent localization to Cdr2 medial cortical node complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased frequency of protein localization to Cdr2 medial cortical node complex during transient localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] synonym: "decreased frequency of protein visits to Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "reduced frequency of protein localization to Cdr2 medial cortical node complex during intermittent localization to Cdr2 medial cortical node complex" EXACT [PomBase:mah] is_a: FYPO:0006607 ! abnormal intermittent protein localization to Cdr2 medial cortical node complex created_by: midori creation_date: 2018-07-04T13:52:50Z [Term] id: FYPO:0006612 name: decreased protein localization to chromatin at transcription termination site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased at sequences that cause RNA polymerase to terminate transcription." [PMID:29899453, PomBase:mah, SO:0002213] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at transcription termination site" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at transcription termination signal" EXACT [SO:0002213] synonym: "decreased protein localization to chromatin at transcription termination site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at transcription termination site during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at transcription termination site" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-07-10T12:42:22Z [Term] id: FYPO:0006613 name: decreased termination of RNA polymerase II transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II occurs to a lower extent than normal. Termination of all transcripts, or a subset of transcripts, may be affected." [GO:0006369, PomBase:mah] synonym: "decreased RNA polymerase II transcription termination" EXACT [GO:0006369] synonym: "decreased termination of RNA polymerase II transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased termination of RNA polymerase II transcription during vegetative growth" EXACT [PomBase:mah] synonym: "reduced termination of RNA polymerase II transcription" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth is_a: FYPO:0004811 ! abnormal termination of RNA polymerase II transcription created_by: midori creation_date: 2018-07-10T13:14:32Z [Term] id: FYPO:0006614 name: increased termination of RNA polymerase II transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II occurs to a greater extent than normal. Termination of all transcripts, or a subset of transcripts, may be affected." [GO:0006369, PomBase:mah] synonym: "increased RNA polymerase II transcription termination" EXACT [GO:0006369] synonym: "increased termination of RNA polymerase II transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased termination of RNA polymerase II transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth is_a: FYPO:0004811 ! abnormal termination of RNA polymerase II transcription created_by: midori creation_date: 2018-07-10T13:20:04Z [Term] id: FYPO:0006615 name: increased cell diameter def: "A cell morphology phenotype in which a cell has a greater diameter (thickness; width) than normal." [PomBase:mah] synonym: "increased cell thickness" EXACT [PomBase:mah] synonym: "increased cell width" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape is_a: FYPO:0001127 ! abnormal cell size created_by: midori creation_date: 2018-07-10T13:54:33Z [Term] id: FYPO:0006616 name: viable vegetative cell with increased cell diameter def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a diameter greater than normal. Cell volume may or may not be increased." [PomBase:mah] synonym: "viable cell with increased cell diameter during vegetative growth" EXACT [PomBase:mah] synonym: "viable vegetative cell with increased cell diameter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable vegetative cell with increased cell thickness" EXACT [PomBase:mah] synonym: "viable vegetative cell with increased cell width" EXACT [PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0002196 ! abnormal vegetative cell shape is_a: FYPO:0006615 ! increased cell diameter relationship: has_part FYPO:0006615 ! increased cell diameter created_by: midori creation_date: 2018-07-10T14:05:59Z [Term] id: FYPO:0006617 name: viable elongated vegetative cell with increased cell diameter def: "A cell morphology phenotype in which a vegetative cell is viable, elongated, and has a greater diameter than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable elongated cell with increased cell diameter during vegetative growth" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell with increased cell diameter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable elongated vegetative cell with increased cell thickness" EXACT [PomBase:mah] synonym: "viable elongated vegetative cell with increased cell width" EXACT [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell is_a: FYPO:0006616 ! viable vegetative cell with increased cell diameter created_by: midori creation_date: 2018-07-10T14:10:01Z [Term] id: FYPO:0006618 name: increased number of Rad52 foci during cellular response to bleomycin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to bleomycin." [PMID:22064477, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during cellular response to bleomycin" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to bleomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to bleomycin during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to DNA damage" RELATED [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2018-07-16T14:06:42Z [Term] id: FYPO:0006619 name: normal nuclear polyadenylated mRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated messenger RNA (mRNA) measured in the nucleus is normal (i.e. indistinguishable from wild type). Total mRNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal nuclear poly(A)+ mRNA level during vegetative growth" EXACT [PomBase:vw] synonym: "normal nuclear polyadenylated messenger RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal nuclear polyadenylated mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "normal nuclear polyadenylated mRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear polyadenylated mRNA transcript level during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2018-07-16T14:33:56Z [Term] id: FYPO:0006620 name: abnormal chromatin organization during recovery from glucose starvation def: "A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is returned to glucose-rich medium following glucose starvation." [GO:0006325, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abnormal chromatin organisation during recovery from glucose starvation" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during recovery from glucose depletion" EXACT [PomBase:vw] synonym: "abnormal chromatin organization during recovery from glucose deprivation" EXACT [PomBase:vw] synonym: "abnormal chromatin organization during recovery from glucose limitation" RELATED [PomBase:mah] synonym: "abnormal chromatin organization following glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2018-07-16T14:45:28Z [Term] id: FYPO:0006621 name: normal H3-K4 deacetylation during recovery from glucose starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deacetylation of lysine at position 4 of histone H3 is normal (i.e. indistinguishable from wild type) when the cell is returned to glucose-rich medium following glucose starvation." [PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal H3-K4 deacetylation during recovery from glucose depletion" EXACT [PomBase:vw] synonym: "normal H3-K4 deacetylation during recovery from glucose deprivation" EXACT [PomBase:vw] synonym: "normal H3-K4 deacetylation during recovery from glucose limitation" RELATED [PomBase:mah] synonym: "normal H3-K4 deacetylation following glucose starvation" EXACT [PomBase:mah] synonym: "normal H3K4 deacetylation during recovery from glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0002495 ! normal protein modification created_by: midori creation_date: 2018-07-16T14:48:17Z [Term] id: FYPO:0006622 name: decreased T-G mismatch DNA binding def: "A molecular function phenotype in which occurrence of binding to double-stranded DNA containing a G/T mispair by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased G/T mispair binding" EXACT [GO:0032137] synonym: "decreased guanine/thymine mispair binding" EXACT [GO:0032137] synonym: "decreased T/G mispair binding" EXACT [GO:0032137] synonym: "decreased thymine/guanine mispair binding" EXACT [GO:0032137] synonym: "reduced T-G mismatch DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2018-07-16T15:09:49Z [Term] id: FYPO:0006623 name: decreased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in the plasma membrane is lower than normal." [PomBase:mah] synonym: "decreased 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate level in plasma membrane" EXACT [CHEBI:16618] synonym: "decreased phosphatidylinositol-3,4,5-trisphosphate level in cell membrane" EXACT [PomBase:mah] synonym: "decreased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "decreased plasma membrane phosphatidylinositol-3,4,5-trisphosphate level" EXACT [PomBase:mah] synonym: "decreased plasma membrane PI(3,4,5)P3 level" EXACT [PomBase:vw] synonym: "reduced phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0006222 ! decreased phosphatidylinositol phosphate level in plasma membrane is_a: FYPO:0006486 ! decreased cellular phosphatidylinositol-3,4,5-trisphosphate level created_by: midori creation_date: 2018-07-16T15:15:45Z [Term] id: FYPO:0006624 name: increased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in the plasma membrane is higher than normal." [PomBase:mah] synonym: "increased 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate level in plasma membrane" EXACT [CHEBI:16618] synonym: "increased phosphatidylinositol-3,4,5-trisphosphate level in cell membrane" EXACT [PomBase:mah] synonym: "increased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "increased plasma membrane phosphatidylinositol-3,4,5-trisphosphate level" EXACT [PomBase:mah] synonym: "increased plasma membrane PI(3,4,5)P3 level" EXACT [PomBase:vw] is_a: FYPO:0001286 ! increased cellular phosphoinositide level is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth is_a: FYPO:0006488 ! increased cellular phosphatidylinositol-3,4,5-trisphosphate level created_by: midori creation_date: 2018-07-16T15:20:41Z [Term] id: FYPO:0006625 name: decreased phosphatidylinositol-4,5-bisphosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the plasma membrane is lower than normal." [PomBase:mah] synonym: "decreased 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate level in plasma membrane" EXACT [CHEBI:18348] synonym: "decreased phosphatidylinositol-4,5-bisphosphate level in cell membrane" EXACT [PomBase:mah] synonym: "decreased phosphatidylinositol-4,5-bisphosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phosphatidylinositol-4,5-bisphosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "decreased plasma membrane phosphatidylinositol-4,5-bisphosphate level" EXACT [PomBase:mah] synonym: "decreased plasma membrane PI(4,5)P2 level" EXACT [PomBase:vw] synonym: "reduced phosphatidylinositol-4,5-bisphosphate level in plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0006222 ! decreased phosphatidylinositol phosphate level in plasma membrane created_by: midori creation_date: 2018-07-16T15:22:27Z [Term] id: FYPO:0006626 name: increased phosphatidylinositol-4,5-bisphosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the plasma membrane is higher than normal." [PomBase:mah] synonym: "increased 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate level in plasma membrane" EXACT [CHEBI:18348] synonym: "increased phosphatidylinositol-4,5-bisphosphate level in cell membrane" EXACT [PomBase:mah] synonym: "increased phosphatidylinositol-4,5-bisphosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phosphatidylinositol-4,5-bisphosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "increased plasma membrane phosphatidylinositol-4,5-bisphosphate level" EXACT [PomBase:mah] synonym: "increased plasma membrane PI(4,5)P2 level" EXACT [PomBase:vw] is_a: FYPO:0001286 ! increased cellular phosphoinositide level is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth created_by: midori creation_date: 2018-07-16T15:24:13Z [Term] id: FYPO:0006627 name: normal phosphatidylinositol-4,5-bisphosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the plasma membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate level in plasma membrane" EXACT [CHEBI:18348] synonym: "normal phosphatidylinositol-4,5-bisphosphate level in cell membrane" EXACT [PomBase:mah] synonym: "normal phosphatidylinositol-4,5-bisphosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phosphatidylinositol-4,5-bisphosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "normal plasma membrane phosphatidylinositol-4,5-bisphosphate level" EXACT [PomBase:mah] synonym: "normal plasma membrane PI(4,5)P2 level" EXACT [PomBase:vw] is_a: FYPO:0001507 ! normal cellular phosphatidylinositol level created_by: midori creation_date: 2018-07-16T15:26:46Z [Term] id: FYPO:0006628 name: decreased phosphatidylinositol-4-phosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the plasma membrane is lower than normal." [PomBase:mah] synonym: "decreased 1-phosphatidyl-1D-myo-inositol 4-phosphate level in plasma membrane" EXACT [CHEBI:37530] synonym: "decreased phosphatidylinositol-4-phosphate level in cell membrane" EXACT [PomBase:mah] synonym: "decreased phosphatidylinositol-4-phosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased phosphatidylinositol-4-phosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "decreased plasma membrane phosphatidylinositol-4-phosphate level" EXACT [PomBase:mah] synonym: "decreased plasma membrane PI(5)P level" EXACT [PomBase:vw] synonym: "reduced phosphatidylinositol-4-phosphate level in plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0006222 ! decreased phosphatidylinositol phosphate level in plasma membrane is_a: FYPO:0006775 ! decreased cellular phosphatidylinositol-4-phosphate level created_by: midori creation_date: 2018-07-16T15:28:17Z [Term] id: FYPO:0006629 name: normal phosphatidylinositol-4-phosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the plasma membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 1-phosphatidyl-1D-myo-inositol 4-phosphate level in plasma membrane" EXACT [CHEBI:37530] synonym: "normal phosphatidylinositol-4-phosphate level in cell membrane" EXACT [PomBase:mah] synonym: "normal phosphatidylinositol-4-phosphate level in plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phosphatidylinositol-4-phosphate level in plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "normal plasma membrane phosphatidylinositol-4-phosphate level" EXACT [PomBase:mah] synonym: "normal plasma membrane PI(5)P level" EXACT [PomBase:vw] is_a: FYPO:0001507 ! normal cellular phosphatidylinositol level created_by: midori creation_date: 2018-07-16T15:30:15Z [Term] id: FYPO:0006630 name: inviable elongated tetranucleate aseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, elongated, has no septum, and contains four nuclei." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated tetranucleate aseptate inviable vegetative cell" EXACT [PomBase:mah] synonym: "inviable elongated tetranucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated tetranucleate aseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; elongated tetranucleate aseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002024 ! inviable elongated multinucleate aseptate vegetative cell is_a: FYPO:0004044 ! elongated tetranucleate vegetative cell created_by: midori creation_date: 2018-07-16T15:37:04Z [Term] id: FYPO:0006631 name: decreased protein localization to chromatin def: "A cell phenotype in which the localization of a protein to chromatin is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin" EXACT [PomBase:mah] is_a: FYPO:0001679 ! abnormal protein localization to chromatin created_by: midori creation_date: 2018-08-08T12:27:14Z [Term] id: FYPO:0006632 name: normal cellular free fatty acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more free fatty acids measured in the cell is normal (i.e. indistinguishable from wild type)." [PMID:30003614, PomBase:mah] synonym: "normal cellular fatty acid level" EXACT [CHEBI:35366] synonym: "normal cellular free fatty acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular free fatty acid level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of free fatty acids in cell" EXACT [PomBase:vw] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2018-08-08T16:41:29Z [Term] id: FYPO:0006633 name: increased cell length def: "A cell morphology phenotype in which cell length, i.e. the maximum distance between the cell ends, is greater than normal." [PomBase:mah] comment: This term includes both elongated cells, in which both the length and length:diameter ratio are increased relative to wild type, and cells that have increased length but a wild-type length:diameter ratio. is_a: FYPO:0001126 ! abnormal cell shape is_a: FYPO:0001127 ! abnormal cell size created_by: midori creation_date: 2018-08-10T10:56:43Z [Term] id: FYPO:0006634 name: increased vegetative cell length def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cell length, i.e. the maximum distance between the cell ends, is greater than normal." [PomBase:mah] comment: This term includes both elongated cells, in which both the length and length:diameter ratio are increased relative to wild type, and cells that have increased length but a wild-type length:diameter ratio. synonym: "increased cell length during vegetative growth" EXACT [PomBase:mah] synonym: "increased vegetative cell length during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape is_a: FYPO:0006633 ! increased cell length created_by: midori creation_date: 2018-08-10T10:57:42Z [Term] id: FYPO:0006635 name: normal protein localization to cell tip during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to cell end during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip during interphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cell tip during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001587 ! normal protein localization to cell tip during vegetative growth created_by: midori creation_date: 2018-08-10T11:35:10Z [Term] id: FYPO:0006636 name: mislocalized protein distributed in cell cortex def: "A cell phenotype in which a protein is detected abnormally distributed throughout the cell cortex. The protein may normally be restricted to part of the cell cortex, or not normally located in the cell cortex at all." [PomBase:mah] comment: This term can be used for protein that do not normally localize to discrete cytoplasmic regions, or for proteins that do normally show punctate localization but with such localization increased in a mutant. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein distributed in cell cortex" EXACT [PomBase:mah] synonym: "mislocalized protein distributed at cell surface" RELATED [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth created_by: midori creation_date: 2018-08-10T11:54:39Z [Term] id: FYPO:0006637 name: decreased protein localization to cell cortex of cell tip, with protein distributed in cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is decreased, and an increased amount of the protein is instead detected distributed throughout the cell cortex." [PMID:29930085, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell cortex of cell tip, with protein distributed in cortex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex of cell end, with protein distributed in cortex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex of cell tip, with protein distributed in cortex, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to of cell tip cortex, with protein distributed in cortex" EXACT [PomBase:mah] synonym: "reduced protein localization to cell cortex of cell tip, with protein distributed in cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth is_a: FYPO:0003208 ! decreased protein localization to cell tip, with protein distributed in plasma membrane or cortex is_a: FYPO:0005798 ! decreased protein localization to cell cortex of cell tip during vegetative growth relationship: has_part FYPO:0006636 ! mislocalized protein distributed in cell cortex created_by: midori creation_date: 2018-08-10T11:59:24Z [Term] id: FYPO:0006638 name: decreased protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex." [PMID:29930085, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to medial cortex, with protein distributed in cortex, during vegetative growth" NARROW [PomBase:mah] synonym: "decreased protein localisation to medial cortex, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to medial cortex during vegetative growth, with protein distributed in cell cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to medial cortex, with protein distributed in cell cortex, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to medial ring, with protein distributed in cell cortex, during vegetative growth" EXACT [GO:0031097, GO:0071574] synonym: "reduced protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002557 ! decreased protein localization to medial cortex during vegetative growth is_a: FYPO:0007405 ! abnormal protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth created_by: midori creation_date: 2018-08-10T12:04:41Z [Term] id: FYPO:0006639 name: normal vegetative cell diameter def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal diameter (thickness; width)." [PomBase:mah] synonym: "normal cell diameter during vegetative growth" EXACT [PomBase:mah] synonym: "normal vegetative cell diameter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal vegetative cell thickness" EXACT [PomBase:mah] synonym: "normal vegetative cell width" EXACT [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2018-08-10T12:54:26Z [Term] id: FYPO:0006640 name: abnormal protein localization to mitotic spindle pole body during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is abnormal during anaphase B of mitosis." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to mitotic spindle pole body during anaphase B" EXACT [PomBase:mah] synonym: "abnormal protein localization to mitotic SPB during anaphase B" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle pole body during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle pole body during mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body created_by: midori creation_date: 2018-08-10T14:11:19Z [Term] id: FYPO:0006641 name: normal protein localization to kinetochore during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during metaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during metaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0005779 ! normal protein localization to kinetochore during mitosis created_by: midori creation_date: 2018-08-10T14:18:30Z [Term] id: FYPO:0006642 name: decreased protein localization to nucleus during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth is_a: FYPO:0002338 ! abnormal protein localization to nuclear periphery created_by: midori creation_date: 2018-08-10T14:20:01Z [Term] id: FYPO:0006643 name: mitotic spindle collapse without elongation during metaphase def: "A cell phenotype in which a short mitotic spindle assembles and elongates during prophase, but does not elongate further and eventually collapses during metaphase." [PMID:28178520, PomBase:mah] synonym: "broken mitotic spindle without elongation during metaphase" RELATED [PomBase:vw] synonym: "mitotic spindle breakage without elongation during metaphase" EXACT [PomBase:vw] synonym: "mitotic spindle collapse without elongation during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle collapse without extension during metaphase" EXACT [PomBase:vw] synonym: "spindle collapse without elongation during metaphase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle collapse without elongation during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0006475 ! mitotic spindle collapse created_by: midori creation_date: 2018-08-10T14:22:10Z [Term] id: FYPO:0006644 name: decreased protein localization to mitotic spindle midzone, with protein distributed along spindle, during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased, and some of the protein is present along the entire length of the spindle, during anaphase B of mitosis." [PMID:28178520, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle midzone, with protein distributed along spindle, during anaphase B" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic spindle midzone, with protein distributed along spindle, during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone, with protein distributed along spindle, during anaphase B during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle midzone, with protein distributed along spindle, during anaphase B of mitosis" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle midzone, with protein distributed along spindle, during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0003841 ! decreased protein localization to mitotic spindle midzone is_a: FYPO:0004833 ! decreased protein localization to mitotic spindle midzone during anaphase B created_by: midori creation_date: 2018-08-10T14:35:59Z [Term] id: FYPO:0006645 name: normal protein localization to mitotic spindle midzone during metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during metaphase is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle midzone during metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle midzone during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to spindle midzone during metaphase during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004692 ! normal protein localization to mitotic spindle midzone created_by: midori creation_date: 2018-08-10T14:47:00Z [Term] id: FYPO:0006646 name: normal duration of mitotic prometaphase def: "A cell cycle phenotype in which the duration of prometaphase of mitosis normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal duration of mitotic prometaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal duration of prometaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal duration of prometaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0002740 ! normal mitotic cell cycle phase created_by: midori creation_date: 2018-08-10T14:54:15Z [Term] id: FYPO:0006647 name: abnormal 5'-3' DNA/RNA helicase activity def: "A molecular function phenotype in which the observed rate of 5'-3' DNA/RNA helicase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2018-08-13T15:01:20Z [Term] id: FYPO:0006648 name: decreased 5'-3' DNA/RNA helicase activity def: "A molecular function phenotype in which the observed rate of 5'-3' DNA/RNA helicase activity is decreased." [PomBase:mah] synonym: "reduced 5'-3' DNA/RNA helicase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0006647 ! abnormal 5'-3' DNA/RNA helicase activity created_by: midori creation_date: 2018-08-13T15:01:29Z [Term] id: FYPO:0006649 name: abolished 5'-3' DNA/RNA helicase activity def: "A molecular function phenotype in which 5'-3' DNA/RNA helicase activity is absent." [PomBase:mah] synonym: "5'-3' DNA/RNA helicase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0006647 ! abnormal 5'-3' DNA/RNA helicase activity created_by: midori creation_date: 2018-08-13T15:01:29Z [Term] id: FYPO:0006650 name: abnormal ATP-dependent protein-DNA complex displacement activity def: "A molecular function phenotype in which the observed rate of an ATP-dependent protein-DNA complex displacement activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2018-08-13T15:04:42Z [Term] id: FYPO:0006651 name: abolished ATP-dependent protein-DNA complex displacement activity def: "A molecular function phenotype in which an ATP-dependent protein-DNA complex displacement activity is absent." [PomBase:mah] synonym: "ATP-dependent protein-DNA complex displacement activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0006650 ! abnormal ATP-dependent protein-DNA complex displacement activity created_by: midori creation_date: 2018-08-13T15:05:04Z [Term] id: FYPO:0006652 name: increased DNA/DNA annealing activity def: "A molecular function phenotype in which the observed rate of a DNA/DNA annealing activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0005438 ! abnormal DNA/DNA annealing activity created_by: midori creation_date: 2018-08-13T15:11:11Z [Term] id: FYPO:0006653 name: normal flap-structured DNA binding def: "A molecular function phenotype in which occurrence of flap-structured DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2018-08-13T15:16:11Z [Term] id: FYPO:0006654 name: normal G-quadruplex DNA binding def: "A molecular function phenotype in which occurrence of G-quadruplex DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal G-quartet DNA binding" EXACT [GO:0051880] synonym: "normal G4 DNA binding" EXACT [PMID:30053106] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2018-08-13T15:18:00Z [Term] id: FYPO:0006655 name: abolished G-quadruplex DNA unwinding def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the unwinding of G-quadruplex DNA structures does not occur." [PomBase:mah] synonym: "abolished G-quadruplex DNA unwinding during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished G-quadruplex DNA unwinding during vegetative growth" EXACT [PomBase:mah] synonym: "abolished G-quartet DNA unwinding" EXACT [PomBase:mah] synonym: "abolished G4 DNA unwinding" EXACT [GO:0044806] synonym: "G-quadruplex DNA unwinding abolished" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2018-08-13T15:36:13Z [Term] id: FYPO:0006656 name: decreased G-quadruplex DNA unwinding def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the unwinding of G-quadruplex DNA structures occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased G-quadruplex DNA unwinding during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased G-quadruplex DNA unwinding during vegetative growth" EXACT [PomBase:mah] synonym: "decreased G-quartet DNA unwinding" EXACT [PomBase:mah] synonym: "decreased G4 DNA unwinding" EXACT [GO:0044806] synonym: "reduced G-quadruplex DNA unwinding" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2018-08-13T15:36:48Z [Term] id: FYPO:0006657 name: abolished acid phosphatase activity during cellular response to phosphate starvation def: "A molecular function phenotype in which acid phosphatase activity is absent during a cellular response to phosphate starvation." [PomBase:mah] synonym: "acid phosphatase activity abolished during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0002244 ! abolished acid phosphatase activity created_by: midori creation_date: 2018-08-20T14:08:47Z [Term] id: FYPO:0006658 name: decreased acid phosphatase activity during cellular response to phosphate starvation def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is decreased during a cellular response to phosphate starvation." [PomBase:mah] synonym: "reduced acid phosphatase activity during cellular response to phosphate starvation" EXACT [PomBase:mah] is_a: FYPO:0001045 ! decreased acid phosphatase activity created_by: midori creation_date: 2018-08-20T14:08:55Z [Term] id: FYPO:0006659 name: delayed onset of protein phosphorylation during mitotic G1/S transition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during the G1/S transition of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein phosphorylation during G1/S transition of mitotic cell cycle" EXACT [GO:0000082] synonym: "delayed onset of protein phosphorylation during mitotic G1/S transition during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of protein/peptide phosphorylation during mitotic G1/S transition" EXACT [PomBase:mah] synonym: "delayed protein phosphorylation during mitotic G1/S transition" EXACT [PomBase:mah] is_a: FYPO:0002830 ! delayed onset of protein phosphorylation during vegetative growth created_by: midori creation_date: 2018-08-22T14:30:58Z [Term] id: FYPO:0006660 name: loss of viability upon G0 to G1 transition def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable upon exiting G0 phase." [PMID:30116786, PomBase:mah] comment: Also see the cell-level term 'inviable cell upon G0 to G1 transition' (FYPO:0000238). Use this term to annotate experiments in which a culture is grown under nitrogen-depleted conditions until cells have entered and remained for some time in G0, and then the number of cells that can exit G0 and form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "loss of mitotic competence upon recovery from cell quiescence" EXACT [PomBase:vw] synonym: "loss of mitotic competence upon recovery from G0" EXACT [PMID:30116786] synonym: "loss of mitotic competence upon recovery from quiescence" EXACT [PomBase:vw] synonym: "loss of viability upon exit from cell quiescence" EXACT [GO:0044838, PomBase:mah] synonym: "loss of viability upon exit from quiescence" EXACT [PomBase:mah] is_a: FYPO:0001178 ! loss of viability upon nitrogen starvation created_by: midori creation_date: 2018-08-29T14:12:46Z [Term] id: FYPO:0006661 name: fragmented nucleus def: "A cell phenotype in which the nucleus is broken into multiple small fragments that are smaller than a normal nucleus." [PomBase:mah] comment: Use 'fragmented DNA' (FYPO:0000160) or one of its descendants if DNA was detected using a method that can resolve molecule sizes (e.g. gel electrophoresis) or detect DNA ends (e.g. TUNEL assay). Otherwise, consider using 'fragmented nucleus' (FYPO:0001919) or one of its descendants. synonym: "fragmented nuclear DNA" RELATED [PomBase:mah] synonym: "loss of nuclear integrity" RELATED [PomBase:al] is_a: FYPO:0002256 ! abnormal nuclear morphology created_by: midori creation_date: 2018-08-29T15:04:42Z [Term] id: FYPO:0006662 name: fragmented nucleus during G0 def: "A cell phenotype observed during G0 phase in which the nucleus is broken into multiple small fragments that are smaller than a normal nucleus." [PomBase:mah] synonym: "degraded nucleus during cell quiescence" RELATED [PomBase:vw] synonym: "fragmented nuclear DNA during G0" RELATED [PomBase:mah] synonym: "fragmented nucleus during cell quiescence" EXACT [PomBase:mah] synonym: "fragmented nucleus during quiescence" EXACT [PomBase:mah] synonym: "loss of nuclear integrity during G0" RELATED [PomBase:al] is_a: FYPO:0006661 ! fragmented nucleus is_a: FYPO:0006667 ! abnormal nuclear morphology during G0 created_by: midori creation_date: 2018-08-29T15:09:39Z [Term] id: FYPO:0006663 name: elongated nucleus def: "A physical cellular phenotype in which the nucleus is longer than normal." [PomBase:mah] synonym: "elongated nuclei" EXACT [PomBase:vw] synonym: "long nucleus" EXACT [PomBase:vw] is_a: FYPO:0002256 ! abnormal nuclear morphology created_by: midori creation_date: 2018-08-29T15:18:04Z [Term] id: FYPO:0006664 name: elongated nucleus during G0 def: "A cell phenotype observed during G0 phase in which the nucleus is longer than normal." [PomBase:mah] synonym: "elongated nuclei during G0" EXACT [PomBase:al] synonym: "elongated nucleus during cell quiescence" EXACT [PomBase:mah] synonym: "elongated nucleus during quiescence" EXACT [PomBase:mah] synonym: "long nucleus during G0" EXACT [PomBase:mah] is_a: FYPO:0006663 ! elongated nucleus is_a: FYPO:0006667 ! abnormal nuclear morphology during G0 created_by: midori creation_date: 2018-08-29T15:19:18Z [Term] id: FYPO:0006665 name: increased nucleophagy during G0 def: "A cellular process phenotype in which autophagy of the nucleus occurs to a greater extent than normal during G0 phase." [GO:0044804, PMID:30116786, PomBase:mah] synonym: "increased autophagy of nucleus during G0" EXACT [GO:0044804] synonym: "increased nucleophagy during cell quiescence" EXACT [PomBase:mah] synonym: "increased nucleophagy during quiescence" EXACT [PomBase:mah] is_a: FYPO:0008085 ! abnormal nucleophagy created_by: midori creation_date: 2018-08-29T15:23:44Z [Term] id: FYPO:0006666 name: increased spatial extent of double-strand break processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a longer distance from the breaks site than normal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang." [GO:0000729, PMID:29697047, PomBase:mah] synonym: "increased spatial extent of double-strand break processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spatial extent of double-strand break processing during vegetative growth" EXACT [PomBase:mah] synonym: "increased spatial extent of double-strand break resection" EXACT [PomBase:mah] synonym: "increased spatial extent of DSB processing" EXACT [PomBase:mah] is_a: FYPO:0002553 ! abnormal double-strand break processing created_by: midori creation_date: 2018-08-30T16:47:20Z [Term] id: FYPO:0006667 name: abnormal nuclear morphology during G0 def: "A physical cellular phenotype observed during G0 phase in which the size, shape, or structure of the nucleus is abnormal." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "abnormal nuclear morphology during cell quiescence" EXACT [GO:0007127] synonym: "abnormal nuclear morphology during quiescence" EXACT [PomBase:mah] synonym: "deformed nucleus during G0" EXACT [PomBase:vw] synonym: "nuclear morphology defects during G0" EXACT [PomBase:mah] is_a: FYPO:0002256 ! abnormal nuclear morphology created_by: midori creation_date: 2018-09-12T16:13:54Z [Term] id: FYPO:0006668 name: normal nuclear morphology during G0 def: "A physical cellular phenotype observed during G0 phase in which the size, shape, or structure of the nucleus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "normal nuclear morphology during cell quiescence" EXACT [GO:0007127] synonym: "normal nuclear morphology during quiescence" EXACT [PomBase:mah] is_a: FYPO:0001673 ! normal nuclear morphology created_by: midori creation_date: 2018-09-12T16:16:44Z [Term] id: FYPO:0006669 name: abnormal mating between three cells def: "A cellular process phenotype in which one cell mates with two partners, leading to the fusion of three cells. The resulting zygote can then undergo sporulation to form an ascus containing more than four spores." [PMID:30089908, PomBase:mah] synonym: "abnormal conjugation between three cells" EXACT [PomBase:mah] synonym: "abnormal mating among three cells" EXACT [PomBase:mah] is_a: FYPO:0000031 ! abnormal mating relationship: has_output FYPO:0003263 ! abnormal sporulation resulting in formation of ascus with more than four spores created_by: midori creation_date: 2018-09-14T13:40:24Z [Term] id: FYPO:0006670 name: meiotic cell cycle entry in haploid cell def: "A cellular process phenotype in which a haploid cell undergoes meiotic cell cycle." [PMID:31278118, PMID:9755190, PomBase:mah, PomBase:mlr] synonym: "haploid meiosis" NARROW [PomBase:al] synonym: "meiosis in haploid cell" RELATED [PomBase:mah] is_a: FYPO:0009006 ! abnormal meiotic cell cycle entry created_by: midori creation_date: 2018-09-14T13:48:44Z [Term] id: FYPO:0006671 name: transient cell fusion during mating def: "A cellular process phenotype in which cells fuse for a much shorter time than normal during mating, separate with incomplete exchange of cytosol contents, and the conjugation pore then reseals." [PMID:30089908, PomBase:mah] synonym: "transient cell fusion during conjugation" EXACT [PomBase:mah] synonym: "transient cytogamy during conjugation" EXACT [PomBase:mah] synonym: "transient cytogamy during mating" EXACT [PomBase:mah] is_a: FYPO:0000412 ! abnormal cell fusion during mating relationship: has_output FYPO:0003263 ! abnormal sporulation resulting in formation of ascus with more than four spores created_by: midori creation_date: 2018-09-14T14:02:13Z [Term] id: FYPO:0006672 name: transient cell fusion during mating followed by meiotic cell cycle entry and sporulation def: "A cellular process phenotype in which mating cells undergo transient cell fusion (cytogamy), and then one or both cells undergo haploid meiosis and sporulation. In transient cytogamy, cells fuse for a much shorter time than normal during mating, separate with incomplete exchange of cytosol contents, and the conjugation pore then reseals." [PMID:30089908, PomBase:mah] synonym: "transient cell fusion during mating followed by meiotic cell cycle entry and sporulation in haploid" EXACT [PomBase:mah] synonym: "transient cytogamy followed by meiotic cell cycle entry and sporulation in haploid" EXACT [PomBase:mah] is_a: FYPO:0000031 ! abnormal mating is_a: FYPO:0000052 ! abnormal meiotic cell cycle is_a: FYPO:0000511 ! abolished nuclear fusion during mating relationship: has_part FYPO:0000511 ! abolished nuclear fusion during mating relationship: has_part FYPO:0009006 ! abnormal meiotic cell cycle entry created_by: midori creation_date: 2018-09-14T14:31:52Z [Term] id: FYPO:0006673 name: decreased DNA content in spore def: "A cell phenotype in which the total amount of DNA in a spore is lower than normal." [PomBase:mah] synonym: "decreased DNA level in spore" EXACT [PomBase:mah] synonym: "DNA content decreased in spore" EXACT [PomBase:mah] synonym: "reduced DNA content in spore" EXACT [PomBase:mah] synonym: "spores with less than 1C DNA content" EXACT [PomBase:vw] is_a: FYPO:0004320 ! altered DNA level created_by: midori creation_date: 2018-09-14T14:41:12Z [Term] id: FYPO:0006674 name: abolished protein localization to nucleus during mating def: "A cell phenotype in which the localization of a protein to the nucleus is abolished during conjugation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus during mating" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during conjugation" EXACT [PomBase:mah] synonym: "nuclear exclusion during mating" RELATED [PomBase:vw] synonym: "nuclear protein exclusion during mating" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished during mating" EXACT [PomBase:mah] is_a: FYPO:0003450 ! abolished protein localization to nucleus created_by: midori creation_date: 2018-09-14T14:51:52Z [Term] id: FYPO:0006675 name: reversed parental genome-dependent asymmetric transcription def: "A transcription regulation phenotype observed during conjugation in which a pattern of transcriptional regulation that normally differs between parental genomes has the opposite parental specificity compared to normal. For example, a gene that is normally transcribed first from the P (h+) parental genome is instead transcribed from the M (h-) genome earlier." [PMID:30089908, PomBase:mah] synonym: "reversed asymmetric transcription from parental genomes" EXACT [PomBase:mah] synonym: "reversed parental genome-dependent transcriptional asymmetry" EXACT [PomBase:mah] is_a: FYPO:0004526 ! abnormal regulation of transcription created_by: midori creation_date: 2018-09-14T14:56:49Z [Term] id: FYPO:0006676 name: decreased transcription during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to hydroxyurea. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "decreased transcription during cellular response to HU" EXACT [PomBase:mah] synonym: "decreased transcription during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcription in response to HU" EXACT [PomBase:mah] synonym: "decreased transcription in response to hydroxyurea" EXACT [PomBase:mah] synonym: "reduced transcription during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth created_by: midori creation_date: 2018-09-14T15:03:08Z [Term] id: FYPO:0006677 name: decreased DNA binding at double-strand break def: "A molecular function phenotype in which occurrence of DNA binding at double-strand break sites by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:30104346, PomBase:mah] synonym: "decreased DNA binding at site of double-strand break" EXACT [PomBase:mah] synonym: "decreased double-stranded DNA break binding" EXACT [PMID:30104346] synonym: "reduced DNA binding at double-strand break" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2018-09-14T15:09:59Z [Term] id: FYPO:0006678 name: increased number of Rad52 foci during cellular response to chromium def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to chromium ions." [PMID:30148840, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of double-strand break sites during vegetative growth' (FYPO:0000455). synonym: "increased number of Rad22 foci during cellular response to chromium" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to chromium during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to chromium during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to chromium ions" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2018-09-14T15:19:55Z [Term] id: FYPO:0006679 name: normal growth on chromium def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chromium ions." [PomBase:mah] synonym: "normal cell population growth in presence of chromium" EXACT [PomBase:mah] synonym: "normal cell population growth on chromium" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on chromium ion" EXACT [PomBase:mah] synonym: "normal cellular response to chromium" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on chromium ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on chromium" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2018-09-14T15:21:23Z [Term] id: FYPO:0006680 name: sensitive to bisphenol A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bisphenol A. Cells stop growing (and may die) at a concentration of bisphenol A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bisphenol A" EXACT [PomBase:mah] synonym: "sensitive to bisphenol A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to bisphenol A during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to BPA" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2018-09-21T14:01:29Z [Term] id: FYPO:0006681 name: increased histone H3-K9 acetylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PMID:19111658, PomBase:mah] synonym: "increased histone H3-K9 acetylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "increased histone H3-K9 acetylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 acetylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah, PomBase:vw] synonym: "increased histone H3K9 acetylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2018-09-21T14:05:56Z [Term] id: FYPO:0006682 name: DEPRECATED increased protein localization to chromatin at centromere outer repeat comment: DEPRECATED We recommend noting which protein(s) were used in the assay when annotating to this term. comment: replaced by increased protein localization to heterochromatin at centromere outer repeat property_value: seeAlso FYPO:0004237 is_obsolete: true [Term] id: FYPO:0006683 name: normal histone H3-K9 methylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K9 methylation at centromere inner repeat during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone H3-K9 methylation at centromere imr during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 methylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 methylation at centromeric inner repeat region during vegetative growth" EXACT [PMID:24210919] synonym: "normal histone H3K9me at centromere inner repeat during vegetative growth" EXACT [GO:0010452, PomBase:mah] synonym: "normal histone lysine H3 K9 methylation at centromere inner repeat during vegetative growth" EXACT [GO:0010452, PomBase:mah] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth created_by: midori creation_date: 2018-09-21T14:22:09Z [Term] id: FYPO:0006684 name: decreased centromeric transcript binding def: "A molecular function phenotype in which an interaction between a protein and RNAs transcribed from the centromeric region is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PMID:19111658, PomBase:mah] synonym: "decreased cen transcript binding" EXACT [PomBase:mah] synonym: "decreased centromeric RNA binding" EXACT [PomBase:mah] synonym: "decreased protein-centromeric transcript interaction" EXACT [PomBase:mah] synonym: "reduced centromeric transcript binding" EXACT [PomBase:mah] is_a: FYPO:0002134 ! decreased protein-RNA interaction created_by: midori creation_date: 2018-09-21T14:23:56Z [Term] id: FYPO:0006685 name: abolished protein localization to mating partner nucleus in zygote def: "A cellular process phenotype observed during mating in which the localization of a protein produced by one cell to the nucleus of its mating partner (i.e. of the opposite mating type) does not occur. Such protein localization normally occurs after cell fusion but prior to karyogamy." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to conjugation partner nucleus in zygote" EXACT [PomBase:mah] synonym: "abolished protein localisation to mating partner nucleus in zygote" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus of opposite mating type cell" EXACT [PomBase:vw] synonym: "abolished protein localization to partner nucleus during mating" EXACT [PomBase:mah] synonym: "nuclear exclusion from mating partner nucleus in zygote" RELATED [PomBase:vw] synonym: "protein localization to mating partner nucleus abolished in zygote" EXACT [PomBase:mah] is_a: FYPO:0003450 ! abolished protein localization to nucleus created_by: midori creation_date: 2018-09-28T14:05:23Z [Term] id: FYPO:0006686 name: decreased DNA double-strand break processing def: "A cellular process phenotype in which DNA double-strand break resection is decreased. DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed." [GO:0000729, PMID:21931565, PomBase:mah] synonym: "decreased DNA double-strand break resection" EXACT [PomBase:mah] synonym: "decreased DNA double-strand break resectioning" EXACT [PomBase:mah] synonym: "decreased DSB processing" EXACT [PomBase:mah] synonym: "reduced DNA double-strand break processing" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2018-09-28T14:33:13Z [Term] id: FYPO:0006687 name: decreased DNA double-strand break processing during double-strand break repair via homologous recombination def: "A cellular process phenotype in which DNA double-strand break resection that occurs as part of double-strand break repair via homologous recombination is decreased. DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed." [PMID:21931565, PomBase:mah] synonym: "decreased DNA double-strand break resection during double-strand break repair via homologous recombination" EXACT [PomBase:mah] synonym: "decreased DNA double-strand break resectioning during double-strand break repair via homologous recombination" EXACT [PomBase:mah] synonym: "decreased DSB processing during double-strand break repair via homologous recombination" EXACT [PomBase:mah] synonym: "reduced DNA double-strand break processing during double-strand break repair via homologous recombination" EXACT [PomBase:mah] is_a: FYPO:0006686 ! decreased DNA double-strand break processing created_by: midori creation_date: 2018-09-28T14:46:18Z [Term] id: FYPO:0006688 name: increased transversion frequency def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which transversion mutations occur at a higher frequency than normal." [PMID:14599746, PomBase:mah] comment: See SO:1000017. is_a: FYPO:0000256 ! mutator created_by: midori creation_date: 2018-10-10T10:31:10Z [Term] id: FYPO:0006689 name: increased insertion/deletion frequency def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which insertion or deletion mutations occur at a higher frequency than normal." [PMID:14599746, PomBase:mah] synonym: "increased indel frequency" RELATED [PomBase:mah] synonym: "increased insertion or deletion frequency" EXACT [PomBase:mah] is_a: FYPO:0000256 ! mutator created_by: midori creation_date: 2018-10-10T10:42:11Z [Term] id: FYPO:0006690 name: obsolete mitotic catastrophe with abnormal chromosome segregation def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell proceeds through the mitotic metaphase/anaphase transition in the presence of an uncorrected problem (such as chromosome structure or kinetochore attachment), and as a result undergoes abnormal chromosome segregation and subsequently dies." [PomBase:mah] comment: This term was made obsolete because "mitotic catastrophe" has not been clearly defined for fission yeast. synonym: "mitotic catastrophe with abnormal chromosome segregation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe with abnormal chromosome segregation during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2018-10-16T13:32:39Z [Term] id: FYPO:0006691 name: obsolete mitotic catastrophe with abnormal nuclear envelope partitioning def: "OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell proceeds through the mitotic metaphase/anaphase transition in the presence of an uncorrected problem (such as chromosome structure or kinetochore attachment), and as a result undergoes abnormal nuclear envelope partitioning and subsequently dies." [PomBase:mah] comment: This term was made obsolete because "mitotic catastrophe" has not been clearly defined for fission yeast. synonym: "cut-like" RELATED [PomBase:vw] synonym: "mitotic catastrophe with abnormal nuclear envelope partitioning during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitotic catastrophe with abnormal nuclear envelope partitioning during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2018-10-16T13:38:48Z [Term] id: FYPO:0006692 name: cut with septum between unequally sized nuclei def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal mitotic sister chromatid separation, producing inviable daughter cells, and in which the septum forms so as to separate the nucleus into two unequal masses, each in one compartment." [PomBase:mah, PomBase:vw] comment: In cells with this phenotype, septation has proceeded despite chromosome segregation failing to complete normally. Chromosome separation is entirely abolished. Consider also annotating to 'cut' (FYPO:0003155) or its descendants, because these phenotypes often co-occur. synonym: "cut with septum between unequally sized nuclei during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut with septum between unequally sized nuclei during vegetative growth" EXACT [PomBase:mah] synonym: "cut with unequally sized nuclei, one either side of septum" EXACT [PomBase:mah] synonym: "septation following abnormal mitotic sister chromatid segregation, with septum between unequally sized nuclei" EXACT [PomBase:mah] is_a: FYPO:0000229 ! cut created_by: midori creation_date: 2018-10-16T14:20:39Z [Term] id: FYPO:0006693 name: decreased histone H3-K4 dimethylation during G0 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal during G0 phase." [PomBase:mah] synonym: "decreased histone H3 K4 dimethylation during G0" EXACT [GO:0044648, PomBase:mah] synonym: "decreased histone H3-K4 dimethylation during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K4 dimethylation during quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3K4 dimethylation during G0" EXACT [PomBase:vw] synonym: "decreased histone H3K4me2 during G0" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K4 dimethylation during G0" EXACT [GO:0044648, PomBase:mah] synonym: "reduced histone H3-K4 dimethylation during G0" EXACT [PomBase:mah] is_a: FYPO:0003871 ! abnormal chromatin organization during G0 is_a: FYPO:0006870 ! abnormal histone methylation created_by: midori creation_date: 2018-10-16T15:15:01Z [Term] id: FYPO:0006694 name: decreased histone H3-K4 trimethylation during G0 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal during G0 phase." [PomBase:mah] synonym: "decreased histone H3 K4 trimethylation during G0" EXACT [GO:0080182, PomBase:mah] synonym: "decreased histone H3-K4 trimethylation during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K4 trimethylation during quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3K4 trimethylation during G0" EXACT [PomBase:vw] synonym: "decreased histone H3K4me3 during G0" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K4 trimethylation during G0" EXACT [GO:0080182, PomBase:mah] synonym: "reduced histone H3-K4 trimethylation during G0" EXACT [PomBase:mah] is_a: FYPO:0003871 ! abnormal chromatin organization during G0 is_a: FYPO:0006870 ! abnormal histone methylation created_by: midori creation_date: 2018-10-16T15:15:28Z [Term] id: FYPO:0006695 name: decreased cellular S-adenosyl-L-methionine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-adenosyl-L-methionine (SAM) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular S-adenosyl-L-methionine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular S-adenosylmethionine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular SAM level during vegetative growth" EXACT [CHEBI:15414, PomBase:al] synonym: "decreased S-adenosyl-L-methionine accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced cellular S-adenosyl-L-methionine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:28:31Z [Term] id: FYPO:0006696 name: decreased cellular S-adenosyl-L-homocysteine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-adenosyl-L-homocysteine (SAH) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular S-adenosyl-L-homocysteine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular S-adenosylhomocysteine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular SAH level during vegetative growth" EXACT [CHEBI:16680, PomBase:al] synonym: "decreased S-adenosyl-L-homocysteine accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced cellular S-adenosyl-L-homocysteine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:30:55Z [Term] id: FYPO:0006697 name: increased cellular methionine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-methionine level" EXACT [PomBase:mah] synonym: "increased cellular methionine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular methionine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of methionine in cell" EXACT [PomBase:mah] synonym: "induced cellular methionine level" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:33:24Z [Term] id: FYPO:0006698 name: decreased cellular 5-phosphoribosyl diphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-phosphoribosyl diphosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased 5-phosphoribosyl diphosphate accumulation" RELATED [PomBase:mah] synonym: "decreased cellular 5-phosphoribosyl diphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular 5-phosphoribosyl diphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PRPP level" EXACT [PomBase:mah] synonym: "reduced cellular 5-phosphoribosyl diphosphate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:36:17Z [Term] id: FYPO:0006699 name: decreased cellular hercynylcysteine sulfoxide level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylcysteine sulfoxide measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular hercynylcysteine sulfoxide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular hercynylcysteine sulphoxide level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased hercynylcysteine sulfoxide level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular hercynylcysteine sulfoxide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:38:07Z [Term] id: FYPO:0006700 name: decreased cellular CDP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of CDP measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular CDP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular CDP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular CDP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:49:58Z [Term] id: FYPO:0006701 name: decreased cellular UMP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UMP measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular UMP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular UMP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular UMP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:50:43Z [Term] id: FYPO:0006702 name: decreased cellular adenine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of adenine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular adenine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular adenine level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular adenine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:51:21Z [Term] id: FYPO:0006703 name: decreased cellular UDP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular UDP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular UDP level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular UDP level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:52:28Z [Term] id: FYPO:0006704 name: decreased cellular sedoheptulose-7-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sedoheptulose-7-phosphate measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular sedoheptulose-7-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular sedoheptulose-7-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular sedoheptulose-7-phosphate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T15:53:18Z [Term] id: FYPO:0006705 name: decreased cellular pentose phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pentose phosphates measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular pentose phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular pentose phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular pentose-phosphate level" EXACT [PomBase:mah] synonym: "decreased pentose phosphate accumulation" RELATED [PomBase:mah] synonym: "reduced cellular pentose phosphate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-16T16:07:39Z [Term] id: FYPO:0006706 name: abolished calcium-transporting ATPase activity def: "A molecular function phenotype in which a calcium-transporting ATPase activity is absent." [PomBase:mah] synonym: "calcium-transporting ATPase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0002116 ! abnormal transmembrane transporter activity created_by: midori creation_date: 2018-10-30T12:06:02Z [Term] id: FYPO:0006707 name: decreased calcium ion transport from cytosol to endoplasmic reticulum def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the movement of calcium ions from the cytosol to the endoplasmic reticulum is decreased." [GO:1903515, PomBase:mah] synonym: "decreased calcium ion transport from cytosol to endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased calcium ion transport from cytosol to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "decreased calcium ion transport from cytosol to ER during vegetative growth" EXACT [PomBase:mah] synonym: "decreased calcium transport from cytosol to endoplasmic reticulum" EXACT [PomBase:mah] synonym: "reduced calcium ion transport from cytosol to endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2018-10-30T12:12:51Z [Term] id: FYPO:0006708 name: abolished protein phosphorylation during glucose starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur when the cell is subject to glucose starvation." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "abolished protein phosphorylation during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during glucose deprivation" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0002678 ! abolished protein phosphorylation created_by: midori creation_date: 2018-10-30T12:46:35Z [Term] id: FYPO:0006709 name: abolished protein phosphorylation during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to salt stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "protein phosphorylation abolished during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2018-10-30T12:47:32Z [Term] id: FYPO:0006710 name: decreased protein phosphorylation during cellular response to alkaline pH def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to a pH above 7." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to alkaline pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to alkaline pH during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to high pH" EXACT [PomBase:al] synonym: "decreased protein phosphorylation in high pH" RELATED [PomBase:al] synonym: "reduced protein phosphorylation during cellular response to alkaline pH" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth created_by: midori creation_date: 2018-10-30T12:48:37Z [Term] id: FYPO:0006711 name: abolished protein phosphorylation during cellular response to alkaline pH def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to a pH above 7." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein phosphorylation during cellular response to alkaline pH during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to alkaline pH during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein phosphorylation during cellular response to high pH" EXACT [PomBase:al] synonym: "abolished protein phosphorylation in high pH" RELATED [PomBase:al] synonym: "protein phosphorylation abolished during cellular response to alkaline pH" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2018-10-30T12:50:09Z [Term] id: FYPO:0006712 name: decreased cellular acetyl-CoA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of acetyl-CoA measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular acetyl-CoA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular acetyl-CoA level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular acetyl-CoA level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-30T12:57:08Z [Term] id: FYPO:0006713 name: increased cellular malonyl-CoA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of malonyl-CoA measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular malonyl-CoA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular malonyl-CoA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased malonyl-CoA accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-30T12:58:50Z [Term] id: FYPO:0006714 name: increased cellular free fatty acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more free fatty acids measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular free fatty acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular free fatty acid level during vegetative growth" EXACT [PomBase:mah] synonym: "increased free fatty acid accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-10-30T12:59:15Z [Term] id: FYPO:0006715 name: large and small daughter nuclei def: "A mitosis phenotype observed in the vegetative growth phase of the life cycle in which the nucleus divides unequally to produce one daughter nucleus that is larger than the other." [PomBase:jh, PomBase:mah, PomBase:vw] comment: This phenotype does not necessarily reflect a chromosome segregation defect. It may instead arise from abnormal nuclear envelope assembly, following normal chromosome segregation. synonym: "large and small daughter nuclei during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large and small daughter nuclei during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology during vegetative growth created_by: midori creation_date: 2018-10-30T13:23:50Z [Term] id: FYPO:0006716 name: large and small daughter nuclei, with unequal nuclear envelope distribution def: "A mitosis phenotype observed in the vegetative growth phase of the life cycle in which chromosomes segregate equally (i.e. normally), but the nuclear envelope is not distributed equally between daughter nuclei. As a result, the nucleus divides unequally to produce one daughter nucleus that is larger than the other." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "large and small daughter nuclei, with unequal nuclear envelope and equal mitotic sister chromatid segregation" EXACT [PomBase:mah] synonym: "large and small daughter nuclei, with unequal nuclear envelope distribution, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large and small daughter nuclei, with unequal nuclear envelope distribution, during vegetative growth" EXACT [PomBase:mah] synonym: "large and small daughter nuclei, with unequal nuclear envelope partitioning" EXACT [PomBase:mah] is_a: FYPO:0006715 ! large and small daughter nuclei created_by: midori creation_date: 2018-10-30T13:23:56Z [Term] id: FYPO:0006717 name: normal growth on sodium chloride def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium chloride, usually at a higher level than in standard media." [PomBase:mah] synonym: "normal cell population growth in presence of sodium chloride" EXACT [PomBase:mah] synonym: "normal cell population growth on sodium chloride" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to sodium chloride" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on NaCl" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on sodium chloride" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2018-10-30T16:18:16Z [Term] id: FYPO:0006718 name: increased duration of protein phosphorylation during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to osmotic stress. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein phosphorylation during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein phosphorylation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein phosphorylation during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0000548 ! increased duration of protein modification during vegetative growth created_by: midori creation_date: 2018-11-01T10:44:39Z [Term] id: FYPO:0006719 name: abolished mitochondrial fission during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission does not occur during a cellular response to osmotic stress. Normally, mitochondria undergo fission when the cell is exposed to hyperosmotic conditions." [PMID:28515144, PomBase:mah] synonym: "abolished mitochondrial fission during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitochondrial fission during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitochondrial fragmentation during cellular response to osmotic stress" EXACT [PMID:28515144] synonym: "mitochondrial fission abolished during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0004340 ! abnormal mitochondrial fission created_by: midori creation_date: 2018-11-01T10:46:07Z [Term] id: FYPO:0006720 name: normal cell cycle regulation during cellular response to osmotic stress def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to osmotic stress is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to osmotic stress." [PMID:28924043, PomBase:mah] synonym: "normal cell cycle delay following osmotic stress" NARROW [PomBase:al] synonym: "normal cell cycle regulation during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell cycle regulation during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell cycle regulation in response to osmotic stress" EXACT [PomBase:mah] synonym: "normal mitotic cell cycle regulation during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2018-11-01T10:56:00Z [Term] id: FYPO:0006721 name: abolished protein localization to Cdr2 medial cortical node complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Cdr2 medial cortical node complex does not occur." [PMID:28924043, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to Cdr2 medial cortical node complex" EXACT [PomBase:mah] synonym: "abolished protein localization to Cdr2 medial cortical node complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from Cdr2 medial cortical node complex" RELATED [PomBase:mah] synonym: "protein localization to Cdr2 medial cortical node complex abolished" EXACT [PomBase:mah] synonym: "protein localization to Cdr2 medial cortical node complex abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! abolished protein localization during vegetative growth created_by: midori creation_date: 2018-11-01T10:59:42Z [Term] id: FYPO:0006722 name: normal protein localization to Cdr2 medial cortical node complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Cdr2 medial cortical node complex is normal (i.e. indistinguishable from wild type)." [PMID:28924043, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to Cdr2 medial cortical node complex" EXACT [PomBase:mah] synonym: "normal protein localization to Cdr2 medial cortical node complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to Cdr2 medial cortical node complex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2018-11-01T11:03:59Z [Term] id: FYPO:0006723 name: decreased protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that normally moves away from Cdr2 medial cortical node complexes during a cellular response to osmotic stress instead remains predominantly in the nodes." [PMID:28924043, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2018-11-01T11:00:42Z [Term] id: FYPO:0006724 name: normal protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which movement of a protein away from Cdr2 medial cortical node complexes during a cellular response to osmotic stress is normal (i.e. indistinguishable from wild type)." [PMID:28924043, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2018-11-01T11:07:02Z [Term] id: FYPO:0006725 name: normal microtubule binding def: "A molecular function phenotype in which occurrence of microtubule binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with microtubules that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2018-11-06T13:45:56Z [Term] id: FYPO:0006726 name: normal CMG complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which CMG complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal CMG complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal CMG complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: midori creation_date: 2018-11-06T13:49:18Z [Term] id: FYPO:0006727 name: abolished mitotic DNA replication elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA strand elongation involved in mitotic nuclear DNA replication does not occur." [PomBase:mah] synonym: "abolished DNA strand elongation involved in mitotic DNA replication" EXACT [PomBase:mah] synonym: "abolished DNA strand elongation involved in nuclear cell cycle DNA replication" EXACT [GO:1902319] synonym: "abolished mitotic DNA replication elongation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitotic DNA replication elongation during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic DNA replication elongation abolished" EXACT [PomBase:mah] is_a: FYPO:0006730 ! abnormal mitotic DNA replication elongation created_by: midori creation_date: 2018-11-06T14:00:35Z [Term] id: FYPO:0006728 name: abolished mitotic DNA replication initiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication does not occur at one or more origins." [PomBase:mah] synonym: "abolished mitotic DNA replication initiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished mitotic DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic DNA replication initiation abolished" EXACT [PomBase:mah] is_a: FYPO:0001344 ! abnormal mitotic DNA replication initiation created_by: midori creation_date: 2018-11-06T14:19:00Z [Term] id: FYPO:0006729 name: decreased protein localization to chromatin distal to replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin distal to replication origins is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin distal to replication origin" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin distal to replication origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin distal to replication origin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin distal to replication origin" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-11-06T14:23:15Z [Term] id: FYPO:0006730 name: abnormal mitotic DNA replication elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which strand elongation during nuclear DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA replication elongation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal DNA replication elongation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal DNA replication strand elongation" EXACT [PomBase:mah] synonym: "abnormal DNA strand elongation involved in nuclear cell cycle DNA replication" EXACT [GO:1902319] is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2018-11-06T14:25:43Z [Term] id: FYPO:0006731 name: decreased CMG complex progression from replication origin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the CMG complex moves away from replication origins to a lesser extent than normal." [PMID:22718908, PomBase:mah] synonym: "decreased CMG complex translocation from replication origin" EXACT [PMID:22718908] synonym: "decreased replicative helicase progression from replication origin" EXACT [PomBase:mah] synonym: "reduced CMG complex progression from replication origin" EXACT [PomBase:mah] is_a: FYPO:0006730 ! abnormal mitotic DNA replication elongation created_by: midori creation_date: 2018-11-06T14:28:43Z [Term] id: FYPO:0006732 name: normal protein localization to chromatin distal to replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to transcribed regions of chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin distal to replication origin" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin distal to replication origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin distal to replication origin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-11-06T14:33:35Z [Term] id: FYPO:0006733 name: normal CMG complex progression from replication origin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which movement of the CMG complex away from replication origins during DNA replication is normal." [PMID:22718908, PomBase:mah] synonym: "normal CMG complex translocation from replication origin" EXACT [PMID:22718908] synonym: "normal replicative helicase progression from replication origin" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2018-11-06T14:35:24Z [Term] id: FYPO:0006734 name: delayed onset of protein localization to chromatin at replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins begins later than normal." [PMID:22718908, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to chromatin at replication origin" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to chromatin at replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to chromatin at replication origins during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to chromatin at replication origin" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-11-06T14:42:23Z [Term] id: FYPO:0006735 name: resistance to tschimganine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tschimganine than normal." [PomBase:mah] synonym: "resistance to TMN" EXACT [PomBase:mah] synonym: "resistance to tschimganine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tschimganine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tschimganine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2018-11-06T14:47:00Z [Term] id: FYPO:0006736 name: stationary phase viability unaffected by tschimganine def: "A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of tschimganine. Normally, wild-type cell populations survive longer in the presence of tschimganine than in its absence." [PMID:29900664, PomBase:mah] comment: Although each cell has a replicative lifespan in that it divides a certain number of times and then dies, replicative lifespan is often measured at the population level, where it is defined by the number of generations at which 50% of the starting cells are dead. synonym: "chronological lifespan unaffected by tschimganine" RELATED [PomBase:mah] synonym: "loss of chronological lifespan extension by tschimganine" RELATED [PomBase:mah] synonym: "loss of stationary phase viability extension in presence of tschimganine" EXACT [PomBase:mah] synonym: "stationary phase viability unaffected by TMN" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2018-11-06T14:54:22Z [Term] id: FYPO:0006737 name: stationary phase viability unaffected by alpha-hibitakanine def: "A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of alpha-hibitakanine. Normally, wild-type cell populations survive longer in the presence of alpha-hibitakanine than in its absence." [PMID:29900664, PomBase:mah] comment: Although each cell has a replicative lifespan in that it divides a certain number of times and then dies, replicative lifespan is often measured at the population level, where it is defined by the number of generations at which 50% of the starting cells are dead. synonym: "chronological lifespan unaffected by alpha-hibitakanine" RELATED [PomBase:mah] synonym: "loss of chronological lifespan extension by alpha-hibitakanine" RELATED [PomBase:mah] synonym: "loss of stationary phase viability extension in presence of alpha-hibitakanine" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2018-11-06T14:59:01Z [Term] id: FYPO:0006738 name: stationary phase viability unaffected by beta-hibitakanine def: "A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of beta-hibitakanine. Normally, wild-type cell populations survive longer in the presence of beta-hibitakanine than in its absence." [PMID:29900664, PomBase:mah] comment: Although each cell has a replicative lifespan in that it divides a certain number of times and then dies, replicative lifespan is often measured at the population level, where it is defined by the number of generations at which 50% of the starting cells are dead. synonym: "chronological lifespan unaffected by beta-hibitakanine" RELATED [PomBase:mah] synonym: "loss of chronological lifespan extension by beta-hibitakanine" RELATED [PomBase:mah] synonym: "loss of stationary phase viability extension in presence of beta-hibitakanine" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2018-11-06T14:59:43Z [Term] id: FYPO:0006739 name: normal protein localization to chromatin at MCB promoters during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is normal (i.e. indistinguishable from wild type)." [PMID:30134042, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at MCB promoters during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at MCB promoters during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at MCB target genes during vegetative growth" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at MCB-containing promoters during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-11-07T14:47:54Z [Term] id: FYPO:0006740 name: increased protein localization to chromatin at MCB promoters during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is increased." [PMID:30134042, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at MCB promoters during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at MCB promoters during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at MCB target genes during vegetative growth" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at MCB-containing promoters during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2018-11-07T14:45:57Z [Term] id: FYPO:0006741 name: increased nucleosome occupancy at MCB promoters def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing one or more MluI cell cycle box factor elements (MCBs). Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:30134042, PomBase:mah] synonym: "increased nucleosome occupancy at MCB promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy at MCB promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased nucleosome occupancy at MCB promoters target genes" RELATED [PomBase:mah] is_a: FYPO:0000854 ! abnormal nucleosome positioning in euchromatin created_by: midori creation_date: 2018-11-07T14:49:27Z [Term] id: FYPO:0006742 name: normal transcription from MCB promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more MluI cell cycle box factor elements (MCBs) is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc." [PMID:30134042, PomBase:mah] synonym: "normal expression of MBF target genes" RELATED [PomBase:mah] synonym: "normal transcription from MCB promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription from MCB promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2018-11-07T14:52:02Z [Term] id: FYPO:0006743 name: decreased protein localization to nucleus during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to osmotic stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to osmotic stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during osmotic stress" EXACT [PomBase:al] synonym: "reduced protein localization to nucleus during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001514 ! decreased protein localization to nucleus during vegetative growth created_by: midori creation_date: 2018-11-09T12:00:30Z [Term] id: FYPO:0006744 name: decreased protein localization to nucleus during cellular response to tschimganine def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to tschimganine." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus during cellular response to tschimganine" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to TMN" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to tschimganine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleus during cellular response to tschimganine during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus during cellular response to tschimganine" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2018-11-09T12:01:39Z [Term] id: FYPO:0006745 name: abnormal cell wall thickness during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the thickness of the cell wall is abnormal. The wall may be uniformly thicker or thinner than normal, or thickness may be irregular." [PomBase:mah] synonym: "abnormal cell wall thickness during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000351 ! abnormal cell wall morphology during vegetative growth created_by: midori creation_date: 2018-11-09T15:04:00Z [Term] id: FYPO:0006746 name: decreased cell wall thickness at cell tip during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thinner than normal at one or both cell tips." [PMID:29689193, PomBase:mah] synonym: "decreased cell wall thickness at cell end during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cell wall thickness at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced cell wall thickness at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "thin cell wall at cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002163 ! decreased cell wall thickness during vegetative growth created_by: midori creation_date: 2018-11-09T15:06:37Z [Term] id: FYPO:0006747 name: asymmetric mitochondrial aggregation at old end def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal, distal to the side of the nucleus near the old cell end." [PMID:8876193, PomBase:mah] synonym: "asymmetric mitochondrial aggregation at old cell end" EXACT [PomBase:mah] synonym: "asymmetric mitochondrial aggregation at old cell tip" EXACT [PomBase:mah] synonym: "asymmetric mitochondrial aggregation at old end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric mitochondrial aggregation at old end during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondria localized to one cell end" RELATED [PomBase:vw] synonym: "monopolar intracellular mitochondrion distribution" RELATED [PomBase:mah] synonym: "monopolar intracellular mitochondrion localisation" RELATED [PomBase:mah] synonym: "monopolar intracellular mitochondrion localization" RELATED [PomBase:mah] synonym: "monopolar mitochondrial aggregation" RELATED [PomBase:mah] synonym: "monopolar mitochondrion distribution" RELATED [PomBase:mah] is_a: FYPO:0003811 ! asymmetric mitochondrial aggregation created_by: midori creation_date: 2018-11-09T15:31:28Z [Term] id: FYPO:0006748 name: decreased pre-tRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more precursor transfer RNAs (pre-tRNA) measured in a cell is lower than normal. pre-tRNA oncludes any unspliced or incompletely spliced tRNA. Total pre-tRNA or a specific pre-tRNA may be affected." [PomBase:vw] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased pre-tRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased pre-tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased pre-tRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "decreased transfer RNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tRNA level during vegetative growth" BROAD [PomBase:mah] synonym: "decreased tRNA primary transcript level during vegetative growth" EXACT [SO:0000210] synonym: "reduced pre-tRNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0008342 ! decreased pre-tRNA or mature level during vegetative growth created_by: midori creation_date: 2018-11-20T14:17:33Z [Term] id: FYPO:0006749 name: increased pre-tRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transfer RNA precursor(s) (pre-tRNA) measured in a cell is higher than normal. Total pre-tRNA or a specific pre-tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased pre-tRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased pre-tRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased pre-tRNA transcript level during vegetative growth" EXACT [PomBase:vw] synonym: "increased transfer RNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased tRNA level during vegetative growth" BROAD [PomBase:mah] synonym: "increased tRNA primary transcript level during vegetative growth" EXACT [SO:0000210] is_a: FYPO:0008101 ! altered tRNA or precursor level during vegetative growth is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: midori creation_date: 2018-11-20T14:19:57Z [Term] id: FYPO:0006750 name: normal pre-tRNA level during nitrogen starvation def: "A cell phenotype in which the amount of one or more transfer RNA precursor(s) (pre-tRNA) measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total pre-tRNA or a specific pre-tRNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal pre-tRNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "normal pre-tRNA level during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal pre-tRNA level during nitrogen deprivation" EXACT [PomBase:mah] synonym: "normal pre-tRNA transcript level during nitrogen starvation" EXACT [PomBase:vw] synonym: "normal transfer RNA precursor level during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal tRNA level during nitrogen starvation" BROAD [PomBase:mah] synonym: "normal tRNA primary transcript level during nitrogen starvation" EXACT [SO:0000210] is_a: FYPO:0001096 ! normal RNA level during nitrogen starvation created_by: midori creation_date: 2018-11-20T14:21:46Z [Term] id: FYPO:0006751 name: increased histone H3-K4 trimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 in heterochromatin at subtelomeric regions occurs to a greater extent than normal." [PMID:29632066, PomBase:mah] synonym: "increased histone H3 K4 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K4 trimethylation at subtelomeres during vegetative growth" EXACT [PomBase:al] synonym: "increased histone H3-K4 trimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K4 trimethylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "increased histone H3K4me3 at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000869 ! increased histone methylation during vegetative growth is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2018-11-20T15:21:00Z [Term] id: FYPO:0006752 name: increased histone H4-K16 acetylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in heterochromatin at subtelomeric regions occurs to a greater extent than normal." [PMID:29632066, PomBase:mah] synonym: "increased histone H4-K16 acetylation at subtelomere during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K16 acetylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K16 acetylation at subtelomeric heterochromatin region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H4K16 acetylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased subtelomeric heterochromatin histone H4K16 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0007632 ! increased histone H4-K16 acetylation during vegetative growth created_by: midori creation_date: 2018-11-20T15:23:15Z [Term] id: FYPO:0006753 name: decreased histone H4-K20 dimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 in heterochromatin at subtelomeric regions occurs to a lower extent than normal." [PMID:29632066, PomBase:mah] synonym: "decreased histone H4 K20 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "decreased histone H4-K20 dimethylation at subtelomeres during vegetative growth" EXACT [PomBase:al] synonym: "decreased histone H4-K20 dimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H4-K20 dimethylation at telomeric heterochromatin during vegetative growth" RELATED [PomBase:mah, PomBase:vw] synonym: "decreased histone H4K20me2 at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H4 K20 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0034772, PomBase:mah] synonym: "reduced histone H4-K20 dimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005028 ! decreased H4-K20 dimethylation during vegetative growth created_by: midori creation_date: 2018-11-20T15:27:11Z [Term] id: FYPO:0006754 name: decreased promoter-enhancer looping during glucose starvation def: "A cellular process phenotype in which promoter-enhancer looping occurs to a lower extent than normal when the cell is subject to glucose starvation. Promoter-enhancer looping is mediated by interactions between proteins bound to DNA at promoters and at enhancers, or by a single protein binding at both sites." [PMID:28934464, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased promoter-enhancer looping during glucose depletion" EXACT [PomBase:mah] synonym: "decreased promoter-enhancer looping during glucose deprivation" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2018-11-20T15:39:37Z [Term] id: FYPO:0006755 name: decreased chromatin binding at promoter element during glucose starvation def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more specific promoter element(s) is decreased when the cell is subject to glucose starvation." [PMID:28934464, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased chromatin binding at promoter element during glucose depletion" EXACT [PomBase:mah] synonym: "decreased chromatin binding at promoter element during glucose deprivation" RELATED [PomBase:mah] synonym: "reduced chromatin binding at promoter element during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding created_by: midori creation_date: 2018-11-20T15:51:09Z [Term] id: FYPO:0006756 name: increased chromatin binding at promoter element during glucose starvation def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more specific promoter element(s) is increased when the cell is subject to glucose starvation." [PMID:28934464, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "increased chromatin binding at promoter element during glucose depletion" EXACT [PomBase:mah] synonym: "increased chromatin binding at promoter element during glucose deprivation" RELATED [PomBase:mah] is_a: FYPO:0002980 ! increased chromatin binding created_by: midori creation_date: 2018-11-20T15:53:42Z [Term] id: FYPO:0006757 name: normal chromatin binding at promoter element during glucose starvation def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more specific promoter element(s) is normal (i.e. indistinguishable from wild type) when the cell is subject to glucose starvation." [PMID:28934464, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal chromatin binding at promoter element during glucose depletion" EXACT [PomBase:mah] synonym: "normal chromatin binding at promoter element during glucose deprivation" RELATED [PomBase:mah] is_a: FYPO:0003086 ! normal chromatin binding created_by: midori creation_date: 2018-11-20T15:54:33Z [Term] id: FYPO:0006758 name: protein absent from cell during mitotic G1 phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect during G1 phase of the mitotic cell cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein absent from cell during G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "protein absent from cell during G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "undetectable cellular protein level during mitotic G1 phase" EXACT [PomBase:al] is_a: FYPO:0001984 ! protein absent from cell during vegetative growth created_by: midori creation_date: 2018-11-20T15:57:42Z [Term] id: FYPO:0006759 name: abnormal meiotic chromosome organization def: "A cellular process phenotype in which chromosome organization is abnormal during the meiotic cell cycle." [GO:0070192, PomBase:mah] synonym: "abnormal chromosome organization during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal chromosome organization involved in meiotic cell cycle" EXACT [GO:0070192] synonym: "abnormal meiotic chromosome organisation" EXACT [PomBase:mah] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process created_by: midori creation_date: 2018-11-20T16:13:35Z [Term] id: FYPO:0006760 name: abnormal centromere detachment from spindle pole body during meiotic chromosome organization def: "A cellular process phenotype in which centromeres do not detach properly from the spindle pole body (SPB) during the meiotic cell cycle. Normally, centromeres are located at the SPB during mitotic interphase, and upon entering meiosis, telomeres cluster at the SPB, followed by centromere detachment from the SPB." [PMID:27611693, PomBase:mah] synonym: "abnormal centromere detachment from SPB during meiotic chromosome organization" EXACT [PomBase:mah] synonym: "abnormal centromere detachment from spindle pole body during meiotic chromosome organisation" EXACT [PomBase:mah] synonym: "abnormal centromere detachment from spindle pole body involved in chromosome organization involved in meiotic cell cycle" EXACT [GO:0070192] synonym: "abnormal centromere detachment from spindle pole body involved in meiotic chromosome organization" EXACT [PomBase:mah] synonym: "defective centromere detachment from the SPB during karyogamy and meiotic prophase" EXACT [PMID:27611693] is_a: FYPO:0006759 ! abnormal meiotic chromosome organization created_by: midori creation_date: 2018-11-20T16:16:26Z [Term] id: FYPO:0006761 name: increased transcription during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to hydroxyurea. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased transcription during cellular response to HU" EXACT [PomBase:mah] synonym: "increased transcription during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription in response to HU" EXACT [PomBase:mah] synonym: "increased transcription in response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth created_by: midori creation_date: 2018-11-21T14:47:41Z [Term] id: FYPO:0006762 name: normal transcription during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to hydroxyurea. All genes, or a specific subset of genes, may be measured." [PomBase:mah] synonym: "normal transcription during cellular response to HU" EXACT [PomBase:mah] synonym: "normal transcription during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription in response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth created_by: midori creation_date: 2018-11-21T14:49:06Z [Term] id: FYPO:0006763 name: abolished meiotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the meiotic cell cycle DNA replication checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. The meiotic DNA replication checkpoint normally prevents the initiation of meiotic nuclear division until pre-meiotic DNA replication is complete." [GO:0033315, PMID:10521402, PomBase:mah] synonym: "abolished meiotic DNA replication checkpoint" EXACT [PomBase:mah] synonym: "abolished meiotic G2/MI DNA replication checkpoint" EXACT [GO:0033315] is_a: FYPO:0005511 ! meiotic cell cycle checkpoint phenotype created_by: midori creation_date: 2018-11-21T15:02:02Z [Term] id: FYPO:0006764 name: normal activation of meiotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype in which the meiotic cell cycle DNA replication checkpoint is activated at a normal (i.e. indistinguishable from wild type) frequency, under conditions that cause checkpoint activation in wild-type cells. The meiotic DNA replication checkpoint delays the meiotic nuclear division until pre-meiotic DNA replication is complete." [PMID:10521402, PomBase:mah] comment: Checkpoint activation in a mutant usually implies that the mutation is causing problems that the checkpoint detects. synonym: "normal activation of meiotic DNA replication checkpoint" EXACT [PomBase:mah] synonym: "normal activation of meiotic G2/MI DNA replication checkpoint" EXACT [GO:0033315] synonym: "normal meiotic DNA replication checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0005511 ! meiotic cell cycle checkpoint phenotype is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2018-11-21T15:13:22Z [Term] id: FYPO:0006765 name: abnormal protein phosphorylation during meiotic cell cycle def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: midori creation_date: 2018-11-21T15:20:32Z [Term] id: FYPO:0006766 name: decreased protein phosphorylation in absence of meiotic DNA replication checkpoint arrest def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response." [PMID:10521402, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation with abolished meiotic DNA replication checkpoint arrest" EXACT [PomBase:jh] synonym: "reduced protein phosphorylation in absence of meiotic DNA replication checkpoint arrest" EXACT [PomBase:mah] is_a: FYPO:0005577 ! decreased protein phosphorylation during meiotic cell cycle created_by: midori creation_date: 2018-11-21T15:23:43Z [Term] id: FYPO:0006767 name: increased cyclin-dependent protein kinase activity in absence of meiotic DNA replication checkpoint arrest def: "A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response." [PMID:10521402, PomBase:mah] synonym: "increased cyclin-dependent protein kinase activity with abolished meiotic DNA replication checkpoint arrest" EXACT [PomBase:jh] is_a: FYPO:0004319 ! increased cyclin-dependent protein kinase activity created_by: midori creation_date: 2018-11-21T15:27:28Z [Term] id: FYPO:0006768 name: increased protein degradation in absence of meiotic DNA replication checkpoint arrest def: "A cellular process phenotype in which the occurrence of protein degradation is increased during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response." [PMID:10521402, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein breakdown in absence of meiotic DNA replication checkpoint arrest" EXACT [GO:0030163] synonym: "increased protein catabolic process in absence of meiotic DNA replication checkpoint arrest" EXACT [GO:0030163] synonym: "increased protein catabolism in absence of meiotic DNA replication checkpoint arrest" EXACT [GO:0030163] synonym: "increased protein degradation with abolished meiotic DNA replication checkpoint arrest" EXACT [PomBase:jh] is_a: FYPO:0002276 ! increased protein degradation created_by: midori creation_date: 2018-11-21T15:28:53Z [Term] id: FYPO:0006770 name: abnormal kinetochore disassembly during meiotic prophase I def: "A cellular process phenotype in which kinetochore disassembly is abnormal during prophase of meiosis I. Normally, outer kinetochore components delocalize from the centromere during bouquet formation in meiotic prophase I." [PMID:27611693, PomBase:mah] comment: Sister chromatids may separate in meiosis I due to problems with either cohesion or kinetochore attachment to microtubules. Therefore consider also annotating to 'abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation' (FYPO:0000209), 'decreased meiotic sister chromatid cohesion' (FYPO:0002093), or 'merotelic kinetochore attachment during meiosis I' (FYPO:0005638). synonym: "abnormal kinetochore disassembly during prophase I" EXACT [Pombase:mah] synonym: "abnormal kinetochore disassembly during prophase of meiosis I" EXACT [Pombase:mah] synonym: "defective kinetochore disassembly during meiotic prophase I" EXACT [PMID:27611693] is_a: FYPO:0003603 ! abnormal meiosis I created_by: midori creation_date: 2018-11-23T15:01:07Z [Term] id: FYPO:0006771 name: mislocalized actin cortical patches def: "A physical cellular phenotype in which a cell has actin cortical patches in one or more abnormal locations." [PomBase:mah] synonym: "abnormal actin cortical patch location" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch position" EXACT [PomBase:mah] synonym: "mislocalised actin cortical patches" EXACT [PomBase:mah] synonym: "mislocalized actin patches" EXACT [PomBase:mah] synonym: "mislocalized F-actin patches" EXACT [PomBase:mah] is_a: FYPO:0000136 ! cellular physical quality phenotype created_by: midori creation_date: 2018-11-27T14:06:24Z [Term] id: FYPO:0006772 name: dispersed actin cortical patch localization during mating def: "A physical cellular phenotype in which actin cortical patches are localized throughout the cell cortex during mating. Normally, actin cortical patches concentrate in the mating projection tip and conjugation bridge during cell fusion, and then disperse after karyogamy." [PMID:20123972, PomBase:mah] synonym: "delocalised actin cortical patches during mating" EXACT [PomBase:vw] synonym: "delocalized actin cortical patches during mating" EXACT [PomBase:vw] synonym: "depolarized actin cortical patch localization during mating" EXACT [PomBase:vw] synonym: "dispersed actin cortical patch localisation during mating" EXACT [PomBase:mah] synonym: "dispersed actin cortical patch localization during conjugation with cellular fusion" EXACT [GO:0000747] synonym: "dispersed actin cortical patch location during mating" RELATED [PomBase:mah] synonym: "dispersed actin patch localization during mating" EXACT [PomBase:mah] synonym: "dispersed F-actin patch localization during mating" EXACT [PomBase:mah] is_a: FYPO:0006771 ! mislocalized actin cortical patches created_by: midori creation_date: 2018-11-27T14:10:35Z [Term] id: FYPO:0006773 name: abolished protein localization to prospore septin ring def: "A cell phenotype in which the localization of a protein to the prospore septin ring does not occur." [PMID:20123972, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to prospore septin ring" EXACT [PomBase:mah] synonym: "abolished protein localization to forespore septin ring" EXACT [PomBase:mah] synonym: "abolished protein localization to septin ring during prospore membrane assembly" EXACT [PomBase:mah] synonym: "protein localization to prospore septin ring abolished" EXACT [PomBase:mah] is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle created_by: midori creation_date: 2018-11-27T14:38:12Z [Term] id: FYPO:0006774 name: normal protein localization to prospore septin ring def: "A cell phenotype in which the localization of a protein to the prospore septin ring is normal (i.e. indistinguishable from wild type)." [PMID:20123972, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to prospore septin ring" EXACT [PomBase:mah] synonym: "normal protein localization to forespore septin ring" EXACT [PomBase:mah] synonym: "normal protein localization to septin ring during prospore membrane assembly" EXACT [PomBase:mah] is_a: FYPO:0004095 ! normal protein localization during meiotic cell cycle created_by: midori creation_date: 2018-11-27T14:41:43Z [Term] id: FYPO:0006775 name: decreased cellular phosphatidylinositol-4-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-4-phosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-4-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PI(4)P level" EXACT [PomBase:vw] synonym: "decreased cellular PI-4-P level" EXACT [PomBase:al] synonym: "decreased PI-4-P accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphatidylinositol-4-phosphate level" EXACT [PomBase:mah] is_a: FYPO:0001015 ! altered cellular phosphatidylinositol-4-phosphate level is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2018-11-27T14:53:04Z [Term] id: FYPO:0006776 name: decreased phosphatidylinositol-4-phosphate binding def: "A molecular function phenotype in which occurrence of phosphatidylinositol-4-phosphate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds phosphatidylinositol-3-phosphate less than wild type, or that a mutation in one gene decreases phosphatidylinositol-3-phosphate binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "decreased phosphatidylinositol 4-phosphate binding" EXACT [PomBase:mah] synonym: "decreased PtdIns-4-P binding" EXACT [PomBase:mah] synonym: "reduced phosphatidylinositol-4-phosphate binding" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2018-11-27T14:54:25Z [Term] id: FYPO:0006777 name: prospore membrane formation excluding nucleus def: "A cellular process phenotype in which the prospore membrane forms, and may complete closure, without enclosing a nucleus; one or more nuclei may be present in the ascus, not enclosed by any prospore membrane." [PMID:20123972, PomBase:mah] synonym: "ectopic prospore membrane formation" RELATED [PomBase:mah] synonym: "prospore membrane assembly excluding nucleus" EXACT [PomBase:mah] synonym: "prospore membrane closure excluding nucleus" RELATED [PomBase:mah] synonym: "prospore membrane excluding nucleus" EXACT [PomBase:mah] is_a: FYPO:0001914 ! abnormal prospore membrane formation created_by: midori creation_date: 2018-11-27T14:56:36Z [Term] id: FYPO:0006778 name: prospore formation with septin ring dissociated from prospore membrane def: "A cellular process phenotype in which the septin ring does not associate with the prospore membrane during prospore membrane formation and closure. Normally, the septin ring forms in close association with the assembling prospore membrane." [PMID:20123972, PomBase:mah] synonym: "forespore formation with septin ring dissociated from forespore membrane" EXACT [PomBase:mah] synonym: "forespore formation with septin ring dissociated from FSM" EXACT [PomBase:mah] synonym: "prospore septin ring dissociated from prospore membrane" EXACT [PomBase:mah] synonym: "septin ring separated from FSM" EXACT [PomBase:vw] is_a: FYPO:0000196 ! abnormal prospore formation created_by: midori creation_date: 2018-11-27T15:39:08Z [Term] id: FYPO:0006779 name: resistance to spermidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of spermidine than normal." [PomBase:mah] synonym: "resistance to spermidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to spermidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to spermidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2018-11-27T16:17:40Z [Term] id: FYPO:0006780 name: sensitive to Rbin-1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Rbin-1. Cells stop growing (and may die) at a concentration of Rbin-1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Rbin-1" EXACT [PomBase:mah] synonym: "sensitive to Rbin-1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to Rbin-1 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ribozinoindole-1" EXACT [CHEBI:142676] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2018-11-30T09:42:12Z [Term] id: FYPO:0006781 name: resistance to Rbin-1 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of Rbin-1 than normal." [PomBase:mah] synonym: "resistance to Rbin-1 during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to Rbin-1 during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to ribozinoindole-1" EXACT [PomBase:mah] synonym: "resistant to Rbin-1" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2018-11-30T09:46:35Z [Term] id: FYPO:0006782 name: decreased protein level in large ribosomal subunit precursor def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in a complex that is a precursor of the large ribosomal subunit is lower than normal." [PMID:27667686, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the proteasome is decreased, altering the proteasome stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased large ribosomal subunit precursor complex protein level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in large ribosomal subunit precursor during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level in large ribosomal subunit precursor during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in preribosome, large subunit precursor" EXACT [GO:0030687] synonym: "reduced protein level in large ribosomal subunit precursor" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0005003 ! abnormal protein complex composition created_by: midori creation_date: 2018-11-30T09:52:16Z [Term] id: FYPO:0006783 name: increased level of carbohydrate metabolism gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more carbohydrate metabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Carbohydrate metabolism RNAs are transcribed from genes whose products are involved in metabolism of one or more carbohydrates." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased carbohydrate metabolism gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased level of carbohydrate metabolism gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of carbohydrate metabolism gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of carbohydrate metabolism gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2018-12-05T15:12:43Z [Term] id: FYPO:0006784 name: tubular vacuole morphology during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles tubule-shaped." [PMID:30451685, PomBase:mah] synonym: "tubular vacuole morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "tubular-shaped vacuoles during vegetative growth" EXACT [PMID:30451685] is_a: FYPO:0000368 ! abnormal vacuolar morphology during vegetative growth created_by: midori creation_date: 2018-12-07T15:31:06Z [Term] id: FYPO:0006785 name: normal growth on cobalt def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cobalt ions." [PomBase:mah] synonym: "normal cell population growth in presence of cobalt" EXACT [PomBase:mah] synonym: "normal cell population growth on cobalt" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on cobalt ion" EXACT [PomBase:mah] synonym: "normal cellular response to cobalt" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cobalt ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on cobalt" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2018-12-07T15:35:48Z [Term] id: FYPO:0006786 name: normal growth on manganese def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing manganese ions." [PomBase:mah] synonym: "normal cell population growth in presence of manganese" EXACT [PomBase:mah] synonym: "normal cell population growth on manganese" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on manganese ion" EXACT [PomBase:mah] synonym: "normal cellular response to manganese" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on manganese ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on manganese" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2018-12-07T16:08:52Z [Term] id: FYPO:0006787 name: abnormal poly(A)-specific ribonuclease activity def: "A molecular function phenotype in which the observed rate of poly(A)-specific ribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2018-12-13T15:13:46Z [Term] id: FYPO:0006788 name: decreased poly(A)-specific ribonuclease activity def: "A molecular function phenotype in which the observed rate of poly(A)-specific ribonuclease activity is decreased." [PomBase:mah] synonym: "reduced poly(A)-specific ribonuclease activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0006787 ! abnormal poly(A)-specific ribonuclease activity created_by: midori creation_date: 2018-12-13T15:13:54Z [Term] id: FYPO:0006789 name: normal poly(A)-specific ribonuclease activity def: "A molecular function phenotype in which the observed rate of poly(A)-specific ribonuclease activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2018-12-13T15:24:29Z [Term] id: FYPO:0006790 name: meiotic drive suppression def: "A biological process phenotype in which meiotic drive occurs to a lower extent than normal, or does not occur at all, despite the presence of a gene or allele that normally causes drive. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the \"driver\" is overrepresented) among the surviving products of meiosis." [PMID:30475921, PomBase:mah] synonym: "abolished meiotic drive" RELATED [PomBase:mah] synonym: "decreased meiotic drive" RELATED [PomBase:mah] synonym: "suppression of meiotic drive" EXACT [PomBase:mah] is_a: FYPO:0005447 ! abnormal biological process created_by: midori creation_date: 2018-12-13T15:30:16Z [Term] id: FYPO:0006791 name: lipid droplets present in normal numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a normal number of lipid droplets." [PMID:30355493, PomBase:mah] synonym: "lipid droplets present in normal numbers during mitotic cell cycle" EXACT [PomBase:mah] synonym: "lipid droplets present in normal numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2018-12-13T15:43:56Z [Term] id: FYPO:0006792 name: abolished urease activity def: "A molecular function phenotype in which urease activity is absent." [PomBase:mah] synonym: "urease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0003642 ! abnormal urease activity created_by: midori creation_date: 2018-12-18T14:03:25Z [Term] id: FYPO:0006793 name: altered meiotic drive suppression specificity def: "A biological process phenotype in which the specificity between a meiotic driver gene and a drive suppressor gene differs from that observed when both genes are wild type. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the \"driver\" is overrepresented) among the surviving products of meiosis." [PMID:30475921, PomBase:mah] synonym: "abnormal meiotic drive suppression specificity" EXACT [PomBase:mah] synonym: "abnormal specificity of suppression of meiotic drive" EXACT [PomBase:mah] is_a: FYPO:0005447 ! abnormal biological process created_by: midori creation_date: 2018-12-18T14:10:23Z [Term] id: FYPO:0006794 name: inviable branched, swollen vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PMID:11076964, PomBase:mah] synonym: "inviable branched, swollen cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable branched, swollen vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; branched, swollen vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000015 ! branched vegetative cell is_a: FYPO:0002273 ! inviable vegetative cell with abnormal cell morphology is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape relationship: has_part FYPO:0000015 ! branched vegetative cell created_by: midori creation_date: 2018-12-19T15:31:13Z [Term] id: FYPO:0006795 name: abolished protein localization to actin cortical patch, with protein mislocalized to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abolished, and some of the protein is present in the nucleus instead." [PMID:11076964, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to actin cortical patch, with protein mislocalised to nucleus, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to actin cortical patch, with protein mislocalized to nucleus, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to actin cortical patch, with protein mislocalized to nucleus, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to actin patch, with protein mislocalized to nucleus" EXACT [PomBase:mah] synonym: "protein localization to actin cortical patch abolished, with protein mislocalized to nucleus, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth is_a: FYPO:0006116 ! abolished protein localization to actin cortical patch relationship: has_part FYPO:0000784 ! protein mislocalized to nucleus during vegetative growth created_by: midori creation_date: 2018-12-19T15:32:52Z [Term] id: FYPO:0006796 name: abolished protein localization to actin cortical patch, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abolished, and some of the protein is present in the cytoplasm instead." [PMID:11076964, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to actin cortical patch, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to actin cortical patch, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to actin cortical patch, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to actin patch, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] synonym: "protein localization to actin cortical patch abolished, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005501 ! abolished protein localization to cell cortex, with protein mislocalized to cytoplasm, during vegetative growth is_a: FYPO:0006116 ! abolished protein localization to actin cortical patch created_by: midori creation_date: 2018-12-19T15:43:01Z [Term] id: FYPO:0006797 name: delayed onset of cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis begins later than normal." [PomBase:mah] synonym: "delayed cell separation after cytokinesis" EXACT [PomBase:mah] synonym: "delayed onset of cell separation after cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitotic cytokinetic cell separation" EXACT [GO:0000920] synonym: "delayed onset of septum digestion after cytokinesis" EXACT [GO:0000920, PomBase:mah] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: midori creation_date: 2018-12-19T15:45:07Z [Term] id: FYPO:0006798 name: normal nuclear MIS12/MIND complex binding def: "A molecular function phenotype in which the binding of one protein to the nuclear MIS12/MIND complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." [PMID:29180432, PomBase:mah] comment: This term can be used for any interaction with a protein complex that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal nuclear MIS12/MIND complex binding during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nuclear MIS12/MIND complex binding during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005232 ! normal protein complex binding created_by: midori creation_date: 2019-01-04T14:16:29Z [Term] id: FYPO:0006799 name: abolished nuclear MIS12/MIND complex binding def: "A molecular function phenotype in which nuclear MIS12/MIND complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:29180432, PomBase:mah] comment: This term can be used for any interaction with a protein complex that is assayed in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished nuclear MIS12/MIND complex binding during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished nuclear MIS12/MIND complex binding during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear MIS12/MIND complex binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000705 ! abolished protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2019-01-04T14:18:57Z [Term] id: FYPO:0006800 name: decreased centromere clustering at nuclear periphery during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is decreased during interphase of the mitotic cell cycle. Centromere-kinetochore complexes normally cluster near the old spindle pole body during mitotic interphase." [PMID:29180432, PomBase:mah] synonym: "centromere declustering during mitotic interphase" EXACT [PMID:29180432] synonym: "decreased centromere clustering at nuclear periphery during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased centromere clustering at nuclear periphery during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased centromere clustering at SPB during mitotic interphase" RELATED [PomBase:mah] synonym: "decreased centromere clustering at spindle pole body during mitotic interphase" RELATED [GO:0072766, PomBase:mah] synonym: "decreased centromere-SPB clustering during mitotic interphase" RELATED [GO:0072766] synonym: "decreased inter-centromere connection during mitotic interphase" EXACT [PomBase:vw] synonym: "decreased kinetochore clustering at old mitotic spindle pole body during mitotic interphase" RELATED [PomBase:vw] synonym: "decreased kinetochore clustering at SPB during mitotic interphase" RELATED [GO:0072766] synonym: "decreased kinetochore clustering at spindle pole body during mitotic interphase" RELATED [PomBase:mah] synonym: "decreased kinetochore localization at spindle pole body during mitotic interphase" RELATED [GO:0072766] synonym: "decreased mitotic centromere clustering at nuclear periphery during mitotic interphase" EXACT [PomBase:vw] is_a: FYPO:0001779 ! abnormal centromere clustering at nuclear periphery during vegetative growth created_by: midori creation_date: 2019-01-04T14:35:16Z [Term] id: FYPO:0006801 name: spindle pole bodies present in increased numbers during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more spindle pole bodies (SPBs) than normal. In this phenotype, extra SPBs typically contain normal components but seldom attach to spindle microtubules." [PMID:9763447, PomBase:mah] synonym: "excess mitotic spindle pole bodies present" EXACT [PomBase:mah] synonym: "excess spindle pole bodies present during vegetative growth" EXACT [PomBase:mah] synonym: "extra spindle pole bodies present during vegetative growth" EXACT [PomBase:mah] synonym: "multiple mitotic spindle pole bodies" EXACT [PomBase:vw] synonym: "overreplicated mitotic spindle pole bodies" RELATED [PomBase:vw] synonym: "SPBs present in increased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "spindle pole bodies present in greater numbers during vegetative growth" EXACT [PomBase:mah] synonym: "spindle pole bodies present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth relationship: output_of FYPO:0001791 ! abnormal mitotic spindle pole body duplication created_by: midori creation_date: 2019-01-04T14:45:52Z [Term] id: FYPO:0006802 name: dispersed filamentous actin def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which filamentous actin (F-actin) is present in a dispersed form in the cell. Normal F-actin structures (cables and cortical patches) may or may not also be present." [PMID:9786952, PomBase:mah] synonym: "delocalised actin" RELATED [PomBase:vw] synonym: "delocalised F-actin" EXACT [PomBase:mah] synonym: "delocalized F-actin" EXACT [PomBase:mah] synonym: "dispersed actin localization during vegetative growth" EXACT [PomBase:vw] synonym: "dispersed F-actin" EXACT [PomBase:mah] synonym: "dispersed filamentous actin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "dispersed filamentous actin during vegetative growth" EXACT [PomBase:mah] synonym: "dispersed filamentous actin in cell" EXACT [PomBase:mah] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology during vegetative growth created_by: midori creation_date: 2019-01-04T15:00:53Z [Term] id: FYPO:0006803 name: abolished DNA-directed DNA polymerase activity def: "A molecular function phenotype in which a DNA-directed DNA polymerase activity is absent." [PomBase:mah] synonym: "abolished DNA polymerase activity" BROAD [PomBase:mah] synonym: "DNA-directed DNA polymerase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0004519 ! abnormal DNA-directed DNA polymerase activity created_by: midori creation_date: 2019-01-09T10:55:05Z [Term] id: FYPO:0006804 name: normal 5'-deoxyribose-5-phosphate lyase activity def: "A molecular function phenotype in which the observed rate and other catalytic properties of a 5'-deoxyribose-5-phosphate lyase activity are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal dRP lyase activity" BROAD [GO:0051575] synonym: "normal dRPase activity" BROAD [GO:0051575] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2019-01-09T11:23:15Z [Term] id: FYPO:0006805 name: abnormal galactosyltransferase activity def: "A molecular function phenotype in which the observed rate of a galactosyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2019-01-18T10:13:39Z [Term] id: FYPO:0006806 name: decreased galactosyltransferase activity def: "A molecular function phenotype in which the observed rate of a galactosyltransferase activity is decreased." [PomBase:mah] synonym: "reduced galactosyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0006805 ! abnormal galactosyltransferase activity created_by: midori creation_date: 2019-01-18T10:30:51Z [Term] id: FYPO:0006807 name: decreased galactose level in cell surface glycoprotein glycan def: "A phenotype in which the glycan moiety of a glycoprotein found at the cell surface contains a lower amount of galactose residues than normal. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages." [PMID:9839953, PomBase:mah] synonym: "decreased cell surface protein glycan galactosylation" RELATED [PMID:8782411, PomBase:al] synonym: "decreased galactose level in cell surface glycoprotein oligosaccharide" RELATED [PomBase:vw] synonym: "decreased galactose level in glycoprotein glycan at cell surface" EXACT [PomBase:mah] synonym: "decreased level of alpha 1,2-linked galactose residues in cell surface glycoprotein glycan" EXACT [PomBase:mah] synonym: "reduced galactose level in cell surface glycoprotein glycan" EXACT [PomBase:mah] is_a: FYPO:0003354 ! decreased galactose level in glycoprotein glycan created_by: midori creation_date: 2019-01-18T10:35:14Z [Term] id: FYPO:0006808 name: abnormal deadenylation-dependent decay def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules via the deadenylation-dependent pathway, which includes poly(A) tail shortening, is abnormal." [PomBase:mah] synonym: "abnormal deadenylation-dependent decay during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal deadenylation-dependent decay during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GO:0000288] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0006551 ! abnormal gene expression created_by: midori creation_date: 2019-01-18T11:04:50Z [Term] id: FYPO:0006809 name: decreased nuclear-transcribed mRNA poly(A) tail shortening def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which shortening of the poly(A) tail of a messenger RNA (mRNA) molecule is decreased." [PomBase:mah] synonym: "decreased nuclear-transcribed mRNA poly(A) tail shortening during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nuclear-transcribed mRNA poly(A) tail shortening during vegetative growth" EXACT [PomBase:mah] synonym: "reduced nuclear-transcribed mRNA poly(A) tail shortening" EXACT [PomBase:mah] is_a: FYPO:0006808 ! abnormal deadenylation-dependent decay created_by: midori creation_date: 2019-01-18T11:06:51Z [Term] id: FYPO:0006810 name: decreased gross chromosomal rearrangement def: "A cell phenotype in which large chromosomal rearrangements occur less frequently than in wild type cells. Chromosomal rearrangements may include deletions, duplications, inversions, and translocations." [PMID:30652128, PomBase:mah] synonym: "decreased occurrence of gross chromosomal rearrangement" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2019-01-28T15:37:25Z [Term] id: FYPO:0006811 name: normal gross chromosomal rearrangement frequency def: "A cell phenotype in which large chromosomal rearrangements occur at a normal (i.e. indistinguishable from wild type) frequency. Chromosomal rearrangements may include deletions, duplications, inversions, and translocations." [PMID:30652128, PomBase:mah] synonym: "normal occurrence of gross chromosomal rearrangement" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-01-28T16:55:00Z [Term] id: FYPO:0006812 name: decreased protein level in RNA polymerase II core complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the RNA polymerase II core complex is lower than normal." [PMID:10503538, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the proteasome is decreased, altering the proteasome stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level in RNA polymerase II complex" BROAD [GO:0005665] synonym: "decreased protein level in RNA polymerase II core complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level in RNA polymerase II core complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in RNAP II core complex" EXACT [PomBase:mah] synonym: "decreased RNA polymerase II core complex protein level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level in RNA polymerase II core complex" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0005003 ! abnormal protein complex composition created_by: midori creation_date: 2019-01-28T15:38:06Z [Term] id: FYPO:0006813 name: abolished histone H3-K9 trimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions does not occur." [PMID:30652128, PomBase:mah] synonym: "abolished histone H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at centromere CENP-A containing region during vegetative growth" RELATED [PomBase:vw] synonym: "abolished histone H3-K9 trimethylation at centromere imr during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3-K9 trimethylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:vw] synonym: "abolished histone H3K9me3 at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [GO:0036124, PomBase:mah] synonym: "histone H3-K9 trimethylation abolished at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 trimethylation absent at centromere inner repeat during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0008368 ! abolished histone H3-K9 trimethylation at centromere during vegetative growth created_by: midori creation_date: 2019-01-30T15:25:34Z [Term] id: FYPO:0006814 name: increased histone H3-K9 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PMID:30652128, PomBase:mah] synonym: "abnormal histone H3-K9 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K9 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3-K9 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal histone H3-K9 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K9 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0043970, PomBase:vw] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth is_a: FYPO:0002363 ! increased histone H3 acetylation during vegetative growth created_by: midori creation_date: 2019-01-30T15:31:33Z [Term] id: FYPO:0006815 name: increased histone H3-K14 acetylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PMID:30652128, PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "increased histone H3-K14 acetylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah, PomBase:vw] synonym: "increased histone H3K14 acetylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2019-01-30T15:36:27Z [Term] id: FYPO:0006816 name: normal histone H3-K9 acetylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PMID:30652128, PomBase:mah] synonym: "normal histone H3-K9 acetylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "normal histone H3-K9 acetylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 acetylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah, PomBase:vw] synonym: "normal histone H3K9 acetylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003223 ! normal histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2019-01-30T15:39:05Z [Term] id: FYPO:0006817 name: normal histone H3-K14 acetylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PMID:30652128, PomBase:mah] synonym: "normal histone H3-K14 acetylation at centromere imr during vegetative growth" EXACT [PomBase:mah, SO:0001798] synonym: "normal histone H3-K14 acetylation at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K14 acetylation at centromere inner repeat region during vegetative growth" EXACT [PomBase:mah, PomBase:vw] synonym: "normal histone H3K14 acetylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003224 ! normal histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2019-01-30T15:39:10Z [Term] id: FYPO:0006818 name: decreased protein localization to chromatin at centromere outer repeat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere outer repeat regions is decreased." [PMID:30652128, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at centromere outer repeat" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere otr" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "reduced protein localization to chromatin at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2019-01-30T15:43:53Z [Term] id: FYPO:0006819 name: normal vegetative cell growth rate def: "A cellular process phenotype in which cells elongate at a normal (i.e. indistinguishable from wild type) rate during the vegetative growth phase of the life cycle. Cell growth is the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GO:0016049, PomBase:mah] comment: Note that this term refers to growth at the level of any individual cell, and that it specifies only that the rate of increase in cell size due to metabolism is normal. Other aspects of the cell's biology may be abnormal, and other abnormalities may affect increase in cell number (population growth). Also see 'cell population growth phenotype' (FYPO:0000139) and its descendants. is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2019-02-01T13:09:35Z [Term] id: FYPO:0006820 name: abnormal cell growth rate def: "A cellular process phenotype in which the rate of cell growth is abnormal. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present." [GO:0016049, PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the 'cell population growth' terms. is_a: FYPO:0002862 ! abnormal cell growth created_by: midori creation_date: 2019-02-01T13:17:19Z [Term] id: FYPO:0006821 name: slow vegetative cell growth def: "A cellular process phenotype in which cells elongate more slowly than normal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Note that this term refers to growth, i.e. increase in size, of an individual cell. If you have measured the rate or extent of growth of a culture in liquid medium or on plates, use one of the 'cell population growth' terms. is_a: FYPO:0006820 ! abnormal cell growth rate created_by: midori creation_date: 2019-02-01T13:19:17Z [Term] id: FYPO:0006822 name: viable small vegetative cell with normal cell growth rate def: "A cell morphology phenotype in which a vegetatively growing cell is viable and elongates at a normal rate, but divides when a shorter time than normal has elapsed since the previous cell division. Daughter cells therefore have an abnormally low volume. Note that these small viable cells result from a cell cycle size regulation defect." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "mitosis with small cell size and normal cell growth rate" RELATED [PomBase:vw] synonym: "reduced size at cell division with normal cell growth rate" RELATED [PomBase:vw] synonym: "small viable vegetative cell with normal cell growth rate" EXACT [PomBase:mah] synonym: "viable small cell with normal cell growth rate during vegetative growth" EXACT [PomBase:mah] synonym: "viable small vegetative cell with normal cell growth rate" BROAD [] synonym: "viable small vegetative cell with normal cell growth rate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable small vegetative cell with premature mitosis" EXACT [PomBase:vw] synonym: "wee" EXACT [PomBase:jh, PomBase:mah] is_a: FYPO:0000648 ! viable small vegetative cell relationship: has_part FYPO:0001046 ! premature mitosis relationship: has_part FYPO:0006819 ! normal vegetative cell growth rate created_by: midori creation_date: 2019-02-01T13:31:57Z [Term] id: FYPO:0006823 name: viable small vegetative cell with slow cell growth def: "A cell morphology phenotype in which a vegetatively growing cell is viable, but elongates at a slower rate than normal and divides with an abnormally low volume." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "mitosis with small cell size and slow cell growth" RELATED [PomBase:vw] synonym: "reduced size at cell division with slow cell growth" RELATED [PomBase:vw] synonym: "small viable vegetative cell with slow cell growth" EXACT [PomBase:mah] synonym: "viable small cell with slow cell growth during vegetative growth" EXACT [PomBase:mah] synonym: "viable small vegetative cell with slow cell growth during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000648 ! viable small vegetative cell is_a: FYPO:0006821 ! slow vegetative cell growth relationship: has_part FYPO:0006821 ! slow vegetative cell growth created_by: midori creation_date: 2019-02-01T13:34:34Z [Term] id: FYPO:0006824 name: premature protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body begins earlier than normal." [PMID:12479804, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "precocious protein localization to mitotic spindle pole body" RELATED [PATO:0000694] synonym: "premature protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "premature protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "premature protein localization to spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body created_by: midori creation_date: 2019-02-01T13:48:16Z [Term] id: FYPO:0006825 name: abolished protein localization to mitotic spindle pole body during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body does not occur during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to mitotic spindle pole body during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization to mitotic SPB during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization to mitotic spindle pole body during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to mitotic spindle pole body during mitotic M-phase" RELATED [PomBase:vw] synonym: "abolished protein localization to mitotic spindle pole body during mitotic nuclear division" EXACT [GO:0140014] synonym: "protein absent from mitotic spindle pole body during mitosis" RELATED [PomBase:mah] synonym: "protein localisation to mitotic spindle pole body abolished during mitosis" EXACT [PomBase:mah] synonym: "protein localization to mitotic spindle pole body abolished during mitosis" EXACT [PomBase:mah] synonym: "protein localization to spindle pole body abolished during mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000941 ! abolished protein localization to mitotic spindle pole body created_by: midori creation_date: 2019-02-01T13:54:26Z [Term] id: FYPO:0006826 name: sensitive to 4-fluorophenylalanine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-fluorophenylalanine. Cells stop growing (and may die) at a concentration of 4-fluorophenylalanine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 4-fluorophenylalanine" EXACT [PomBase:mah] synonym: "sensitive to 4-fluorophenylalanine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to 4-fluorophenylalanine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to p-fluoro-phenylalanine" EXACT [PMID:8505375] synonym: "sensitive to p-fluorophenylalanine" EXACT [CHEBI:84060] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-02-01T14:00:32Z [Term] id: FYPO:0006827 name: decreased cytosolic zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in the cytosol is lower than normal." [PomBase:mah] synonym: "decreased cytosolic zinc ion level" EXACT [PomBase:mah] synonym: "decreased cytosolic zinc ion level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cytosolic zinc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of zinc ions in cytosol" EXACT [PomBase:mah] synonym: "decreased levels of free cytosolic zinc" EXACT [PomBase:vw] synonym: "reduced cytosolic zinc level" EXACT [PomBase:mah] is_a: FYPO:0001534 ! decreased cellular zinc level is_a: FYPO:0001605 ! decreased level of substance in cytosol created_by: midori creation_date: 2019-02-06T15:58:13Z [Term] id: FYPO:0006828 name: increased cytosolic zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in the cytosol is higher than normal." [PomBase:mah] synonym: "increased cytosolic zinc ion level" EXACT [PomBase:mah] synonym: "increased cytosolic zinc ion level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cytosolic zinc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of zinc ions in cytosol" EXACT [PomBase:mah] synonym: "increased levels of free cytosolic zinc" EXACT [PomBase:vw] is_a: FYPO:0001552 ! increased cellular zinc level is_a: FYPO:0001948 ! increased level of substance in cytosol created_by: midori creation_date: 2019-02-06T16:12:06Z [Term] id: FYPO:0006829 name: normal RNA level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to zinc ion starvation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to zinc ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "normal RNA level during zinc ion starvation" EXACT [PomBase:al] synonym: "normal RNA level in response to zinc ion starvation" EXACT [PomBase:vw] synonym: "normal transcript level during cellular response to zinc ion starvation" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2019-02-06T16:22:34Z [Term] id: FYPO:0006830 name: normal RNA level during cellular response to replete zinc def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to replete levels of zinc ion is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PMID:29529046, PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal mRNA level during cellular response to replete zinc" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to replete zinc" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to replete zinc during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to replete zinc during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during replete zinc" EXACT [PomBase:al] synonym: "normal RNA level in response to replete zinc" EXACT [PomBase:vw] synonym: "normal transcript level during cellular response to replete zinc" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2019-02-06T16:23:50Z [Term] id: FYPO:0006831 name: delayed onset of primary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins later than normal." [GO:0031671, PomBase:mah] synonym: "delayed onset of primary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of primary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of primary cell septum formation" EXACT [PomBase:mah] synonym: "delayed onset of primary septum biogenesis" EXACT [PomBase:mah] synonym: "delayed onset of primary septum synthesis" RELATED [PomBase:mah] synonym: "delayed primary cell septum biogenesis" EXACT [PomBase:mah] is_a: FYPO:0003890 ! abnormal primary cell septum biogenesis created_by: midori creation_date: 2019-02-11T15:24:25Z [Term] id: FYPO:0006832 name: premature primary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins earlier than normal." [GO:0031671, PomBase:mah] synonym: "advanced primary cell septum biogenesis" EXACT [PomBase:mah] synonym: "premature primary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature primary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "premature primary cell septum formation" EXACT [PomBase:mah] synonym: "premature primary septum biogenesis" EXACT [PomBase:mah] synonym: "premature primary septum synthesis" RELATED [PomBase:mah] is_a: FYPO:0003890 ! abnormal primary cell septum biogenesis created_by: midori creation_date: 2019-02-11T15:27:17Z [Term] id: FYPO:0006833 name: normal onset of primary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [GO:0031671, PomBase:mah] synonym: "normal onset of primary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal onset of primary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "normal onset of primary cell septum formation" EXACT [PomBase:mah] synonym: "normal onset of primary septum biogenesis" EXACT [PomBase:mah] synonym: "normal onset of primary septum synthesis" RELATED [PomBase:mah] synonym: "normal timing of primary cell septum biogenesis" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-02-11T15:30:56Z [Term] id: FYPO:0006834 name: increased rate of primary cell septum biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of primary cell septum biogenesis is increased." [PomBase:al, PomBase:mah] synonym: "decreased duration of primary cell septum biogenesis" RELATED [PomBase:mah] synonym: "increased rate of primary cell septum biogenesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of primary cell septum biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of primary septum biogenesis" EXACT [PomBase:mah] synonym: "increased rate of primary septum synthesis" RELATED [PomBase:mah] is_a: FYPO:0003890 ! abnormal primary cell septum biogenesis created_by: midori creation_date: 2019-02-11T15:37:14Z [Term] id: FYPO:0006835 name: normal glucan endo-1,3-beta-glucanase activity def: "A molecular function phenotype in which the observed rate of glucan endo-1,3-beta-glucanase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group" EXACT [GO:0052861] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2019-02-11T15:57:51Z [Term] id: FYPO:0006836 name: sensitive to magnesium chloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to magnesium chloride. Cells stop growing (and may die) at a concentration of magnesium chloride that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to magnesium chloride" EXACT [PomBase:mah] synonym: "sensitive to magnesium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to magnesium chloride during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to MgCl2" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-03-04T13:42:56Z [Term] id: FYPO:0006837 name: increased protein dephosphorylation during cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during cytokinesis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein dephosphorylation during cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein/peptide dephosphorylation during cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification during vegetative growth is_a: FYPO:0005956 ! abnormal protein dephosphorylation during vegetative growth created_by: midori creation_date: 2019-03-04T14:07:05Z [Term] id: FYPO:0006838 name: abnormal linear element maturation def: "A cellular process phenotype in which linear element maturation is abnormal. Linear element maturation is the close association of assembled LinE complexes with chromatin during meiotic prophase to form mature linear elements." [PMID:30640914, PomBase:mah] synonym: "LinE chromosome loading" EXACT [PMID:30640914] synonym: "LinE focus formation" EXACT [PMID:30640914] is_a: FYPO:0000900 ! abnormal linear element assembly created_by: midori creation_date: 2019-03-04T14:44:04Z [Term] id: FYPO:0006839 name: normal protein-containing complex assembly def: "A cellular process phenotype in which the assembly of a protein complex at the cellular level is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular protein complex assembly" EXACT [GO:0034622] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2019-03-04T14:51:16Z [Term] id: FYPO:0006840 name: normal LinE complex assembly def: "A cellular process phenotype in which LinE complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal linear element protein complex assembly" EXACT [PomBase:mah] is_a: FYPO:0006839 ! normal protein-containing complex assembly created_by: midori creation_date: 2019-03-04T14:53:00Z [Term] id: FYPO:0006841 name: increased duration of meiotic S phase def: "A cellular process phenotype in which the duration of progression through S phase of the meiotic cell cycle (preceding meiosis I) is longer than normal." [PomBase:mah] synonym: "delayed meiotic S phase progression" RELATED [PomBase:mah] synonym: "increased duration of meiotic S phase progression" EXACT [PomBase:mah] synonym: "increased duration of premeiotic DNA replication" RELATED [PomBase:mah] synonym: "prolonged meiotic S phase" EXACT [PomBase:mah] synonym: "prolonged premeiotic DNA replication" RELATED [PomBase:mah] is_a: FYPO:0002220 ! increased duration of meiotic cell cycle phase created_by: midori creation_date: 2019-03-04T14:58:55Z [Term] id: FYPO:0006842 name: normal spatial extent of CENP-A containing nucleosome assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosomes containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a normal (i.e. indistinguishable from wild type) portion of the centromeric region of the chromosome. CENP-A-containing nucleosomes are assembled into chromatin around centromeres, encompassing the central core and centromeric inner repeat regions." [GO:0000729, PMID:28904333, PomBase:mah] synonym: "normal extent of CENP-A containing nucleosome" RELATED [PomBase:vw] synonym: "normal spatial extent of CenH3-containing nucleosome assembly at centromere" RELATED [GO:0034080] synonym: "normal spatial extent of CENP-A containing nucleosome assembly at centromere" EXACT [GO:0034080] synonym: "normal spatial extent of CENP-A containing nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spatial extent of CENP-A containing nucleosome assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal spatial extent of CENP-A deposition" RELATED [GO:0034080] synonym: "normal spatial extent of CENP-A loading" RELATED [GO:0034080] synonym: "normal spatial extent of centromere-specific histone exchange" EXACT [GO:0034080] synonym: "normal spatial extent of centromere-specific nucleosome assembly" EXACT [GO:0034080] synonym: "normal spatial extent of centromeric DNA replication-independent nucleosome assembly" EXACT [GO:0034080] synonym: "normal spatial extent of DNA replication-independent nucleosome assembly at centromere" EXACT [GO:0034080] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-03-04T15:09:53Z [Term] id: FYPO:0006843 name: increased histone H3 localization to chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of histone H3 to chromatin is increased." [PMID:28904333, PomBase:mah] synonym: "increased histone H3 localisation to chromatin" EXACT [PomBase:mah] synonym: "increased histone H3 localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3 localization to chromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2019-03-04T15:21:15Z [Term] id: FYPO:0006844 name: normal H2A.Z level at centromere def: "A cell phenotype in which the amount of the histone variant H2A.Z found associated with chromatin in centromeric regions is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle." [PMID:28904333, PomBase:mah] synonym: "normal H2A.Z level at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal H2A.Z level at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "normal H2A.Z level in chromatin at centromere" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2019-03-04T15:23:09Z [Term] id: FYPO:0006845 name: normal histone methyltransferase activity (H3-K9 specific) activity def: "A molecular function phenotype in which the observed rate of H3-K9 specific histone methyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal H3-K9 specific histone methyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2019-03-04T15:37:15Z [Term] id: FYPO:0006846 name: decreased total protein level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of protein measured in a cell is lower than normal." [PomBase:jh, PomBase:mah] synonym: "decreased total protein accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased total protein content during vegetative growth" EXACT [PomBase:jh] synonym: "decreased total protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced total protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2019-03-13T11:44:19Z [Term] id: FYPO:0006847 name: increased total protein level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of protein measured in a cell is higher than normal." [PomBase:jh, PomBase:mah] synonym: "increased total protein accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased total protein content during vegetative growth" EXACT [PomBase:jh] synonym: "increased total protein level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2019-03-13T11:52:24Z [Term] id: FYPO:0006848 name: decreased total RNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of RNA measured in a cell is lower than normal." [PomBase:jh, PomBase:mah] synonym: "decreased total RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "decreased total RNA content during vegetative growth" EXACT [PomBase:jh] synonym: "decreased total RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced total RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2019-03-13T11:54:06Z [Term] id: FYPO:0006849 name: increased total RNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of RNA measured in a cell is higher than normal." [PomBase:jh, PomBase:mah] synonym: "increased total RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased total RNA content during vegetative growth" EXACT [PomBase:jh] synonym: "increased total RNA level during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2019-03-13T11:54:31Z [Term] id: FYPO:0006850 name: abnormal cell cycle arrest at mitotic G2/M phase transition following single cell division during nitrogen starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition, instead of the normal G1 phase, and after the cell undergoes one cell division instead of the normal two, when the cell is subject to nitrogen starvation." [PMID:9472077, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. This term differs from 'abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation' (FYPO:0001001) because it additionally specifies a single cell division, and from 'single cell division prior to G0 entry' (FYPO:0003877) because it does not apply only to G0, and does specify arrest in G2. synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition following single cell division during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition following single cell division during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal cell cycle arrest in mitotic G2 phase following single cell division during nitrogen starvation" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest at mitotic G2/M phase transition following single cell division during nitrogen starvation" EXACT [PomBase:mah] synonym: "abolished mitotic G2/M phase transition following single cell division during nitrogen starvation" RELATED [PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition following single cell division during nitrogen starvation" EXACT [PomBase:mah] synonym: "mitotic G2 phase arrest following single cell division during nitrogen starvation" EXACT [PomBase:mah] synonym: "one cell division prior to cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation" EXACT [PomBase:al] is_a: FYPO:0001001 ! abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation created_by: midori creation_date: 2019-04-03T14:29:21Z [Term] id: FYPO:0006851 name: decreased duration of meiotic cell cycle phase def: "A cellular process phenotype in which the duration of one or more meiotic cell cycle phases is shorter than normal." [PomBase:mah] synonym: "reduced duration of meiotic cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0000410 ! decreased duration of cell cycle phase is_a: FYPO:0002738 ! abnormal meiotic cell cycle phase created_by: midori creation_date: 2019-04-17T11:23:14Z [Term] id: FYPO:0006852 name: decreased duration of meiotic S phase def: "A cellular process phenotype in which the duration of progression through S phase of the meiotic cell cycle (preceding meiosis I) is shorter than normal." [PomBase:mah] synonym: "decreased duration of premeiotic DNA replication" RELATED [PomBase:mah] synonym: "decreased duration of S phase during meiotic cell cycle" EXACT [PomBase:mah] synonym: "reduced duration of meiotic S phase" EXACT [PomBase:mah] is_a: FYPO:0006851 ! decreased duration of meiotic cell cycle phase created_by: midori creation_date: 2019-04-17T11:23:27Z [Term] id: FYPO:0006853 name: increased protein localization to medial cortex during mitotic telophase def: "A cell phenotype in which the localization of a protein to the medial cortex is increased during mitotic telophase." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to medial cortex during mitotic telophase" EXACT [GO:0071574, PomBase:mah] synonym: "increased protein localization to medial cortex during telophase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to medial ring during mitotic telophase" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001677 ! increased protein localization to medial cortex during vegetative growth created_by: midori creation_date: 2019-04-17T11:36:44Z [Term] id: FYPO:0006854 name: normal growth on EGTA def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing EGTA." [PomBase:mah] synonym: "normal cell population growth in presence of EGTA" EXACT [PomBase:mah] synonym: "normal cell population growth on EGTA" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on ethylene glycol bis(2-aminoethyl)tetraacetic acid" EXACT [CHEBI:30740] synonym: "normal vegetative cell population growth on EGTA" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-04-17T11:42:13Z [Term] id: FYPO:0006855 name: abnormal histone H3-K37 methylation def: "A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K37 methylation" EXACT [PomBase:mah] synonym: "abnormal histone H3K37me" EXACT [PomBase:mah] synonym: "abnormal histone lysine H3 K37 methylation" EXACT [PomBase:mah] is_a: FYPO:0006870 ! abnormal histone methylation created_by: midori creation_date: 2019-04-17T13:37:26Z [Term] id: FYPO:0006856 name: increased histone H3-K37 methylation def: "A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is increased." [PomBase:mah] synonym: "increased histone H3 K37 methylation" EXACT [PomBase:mah] synonym: "increased histone H3K37me" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K37 methylation" EXACT [PomBase:mah] is_a: FYPO:0006855 ! abnormal histone H3-K37 methylation created_by: midori creation_date: 2019-04-17T13:38:02Z [Term] id: FYPO:0006857 name: decreased histone H3-K37 methylation def: "A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is decreased." [PomBase:mah] synonym: "decreased histone H3 K37 methylation" EXACT [PomBase:mah] synonym: "decreased histone H3K37me" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K37 methylation" EXACT [PomBase:mah] synonym: "reduced histone H3-K37 trimethylation" EXACT [PomBase:mah] is_a: FYPO:0006855 ! abnormal histone H3-K37 methylation created_by: midori creation_date: 2019-04-17T13:38:06Z [Term] id: FYPO:0006858 name: abolished histone H3-K37 methylation def: "A cellular process phenotype in which methylation of lysine at position 37 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K37 methylation" EXACT [GO:0010452, PomBase:mah] synonym: "abolished histone H3K37me" EXACT [GO:0010452, PomBase:mah] synonym: "abolished histone lysine H3 K37 methylation" EXACT [GO:0010452, PomBase:mah] synonym: "histone H3-K37 methylation abolished" EXACT [PomBase:mah] synonym: "histone H3-K37 methylation absent" EXACT [PomBase:mah] is_a: FYPO:0006855 ! abnormal histone H3-K37 methylation created_by: midori creation_date: 2019-04-17T13:38:21Z [Term] id: FYPO:0006859 name: decreased mitotic DNA replication at telomere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA replication is decreased in telomeric regions." [PMID:30796050, PomBase:mah] synonym: "decreased DNA replication at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic DNA replication at telomere during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitotic DNA replication at telomere" EXACT [PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2019-04-29T13:55:00Z [Term] id: FYPO:0006860 name: decreased mitotic DNA replication at rDNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA replication is decreased in ribosomal DNA repeats." [PMID:30796050, PomBase:mah] synonym: "decreased DNA replication at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitotic DNA replication at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic DNA replication at ribosomal DNA" EXACT [PomBase:mah] synonym: "reduced mitotic DNA replication at rDNA" EXACT [PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication created_by: midori creation_date: 2019-04-29T13:58:50Z [Term] id: FYPO:0006861 name: mislocalized RNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which an RNA is observed in a particular location where it is not normally found." [PomBase:mah] synonym: "mislocalised RNA during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized RNA during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth relationship: output_of FYPO:0000360 ! abnormal RNA localization during vegetative growth created_by: midori creation_date: 2019-04-29T14:06:34Z [Term] id: FYPO:0006862 name: RNA mislocalized to cytoplasm during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which an RNA that is not normally found in the cytoplasm is observed there." [PMID:29424342, PomBase:mah] synonym: "ectopic RNA localization to cytoplasm during vegetative growth" EXACT [PomBase:vw] synonym: "RNA mislocalised to cytoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "RNA mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0006861 ! mislocalized RNA during vegetative growth created_by: midori creation_date: 2019-04-29T14:07:39Z [Term] id: FYPO:0006863 name: loss of viability following cellular response to bleomycin def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to bleomycin." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown in the presence of hydroxyurea, and then the number of cells viable enough to form a colony upon hydroxyurea removal is measured and compared to wild type. synonym: "decreased viability following cellular response to bleomycin" EXACT [PomBase:mah] synonym: "loss of cell population viability following cellular response to bleomycin" EXACT [PomBase:mah] synonym: "loss of viability following bleomycin exposure" EXACT [PomBase:mah] synonym: "reduced viability following cellular response to bleomycin" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2019-04-29T14:24:15Z [Term] id: FYPO:0006864 name: obsolete cut during cellular response to streptonigrin def: "OBSOLETE. A cut phenotype that is observed when a cell is exposed to streptonigrin. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation." [PomBase:mah] comment: This term was made obsolete because it should be represented using experimental conditions with FYPO:0000229. synonym: "cut during cellular response to rufocromomycin" EXACT [CHEBI:9287] synonym: "cut during cellular response to streptonigrin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cut during cellular response to streptonigrin during vegetative growth" EXACT [PomBase:mah] synonym: "septation following abnormal chromosome segregation during cellular response to streptonigrin" EXACT [PomBase:mah] is_obsolete: true replaced_by: FYPO:0000229 created_by: midori creation_date: 2019-05-01T15:13:29Z [Term] id: FYPO:0006865 name: normal mitotic DNA damage checkpoint during cellular response to streptonigrin def: "A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to streptonigrin. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage." [PomBase:mah] synonym: "normal DNA damage checkpoint during cellular response to streptonigrin during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic DNA damage checkpoint activation during cellular response to streptonigrin" EXACT [PomBase:al] synonym: "normal mitotic DNA damage checkpoint during cellular response to rufocromomycin" EXACT [CHEBI:9287] synonym: "normal mitotic DNA damage checkpoint during cellular response to streptonigrin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001705 ! normal mitotic DNA damage checkpoint created_by: midori creation_date: 2019-05-01T15:16:10Z [Term] id: FYPO:0006866 name: increased rate of protein exchange in actomyosin contractile ring def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the actomyosin contractile ring is increased. Normally, proteins including actin and myosin are turned over between the contractile ring and elsewhere in the cytoplasm; exchange is faster during than before ring constriction." [PMID:30928696, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased rate of protein exchange in actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of protein exchange in actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0004738 ! abnormal actomyosin contractile ring organization is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2019-05-01T15:18:45Z [Term] id: FYPO:0006867 name: abnormal protein localization to cell cortex def: "A cell phenotype in which the localization of a protein to the cell cortex is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell cortex" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2019-05-03T10:49:04Z [Term] id: FYPO:0006868 name: decreased protein localization to cell cortex during meiotic prophase I def: "A cell phenotype in which the localization of a protein to the cell cortex is decreased during prophase of the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell cortex during meiotic prophase I" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex during prophase I" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex during prophase of meiosis I" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex in zygote" RELATED [PomBase:vw] synonym: "reduced protein localization to cell cortex during meiotic prophase I" EXACT [PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0006867 ! abnormal protein localization to cell cortex created_by: midori creation_date: 2019-05-03T10:49:59Z [Term] id: FYPO:0006869 name: abolished histone H3-K36 methylation def: "A cellular process phenotype in which methylation of lysine at position 36 of histone H3 does not occur." [PomBase:mah] synonym: "abolished histone H3 K36 methylation" EXACT [GO:0010452, PomBase:mah] synonym: "abolished histone H3K36me" EXACT [GO:0010452, PomBase:mah] synonym: "abolished histone lysine H3 K36 methylation" EXACT [GO:0010452, PomBase:mah] synonym: "histone H3-K36 methylation abolished" EXACT [PomBase:mah] synonym: "histone H3-K36 methylation absent" EXACT [PomBase:mah] is_a: FYPO:0006870 ! abnormal histone methylation created_by: midori creation_date: 2019-05-03T11:23:43Z [Term] id: FYPO:0006870 name: abnormal histone methylation def: "A cellular process phenotype in which histone methylation is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered." [PomBase:mah] is_a: FYPO:0006458 ! abnormal histone modification created_by: midori creation_date: 2019-05-03T11:27:25Z [Term] id: FYPO:0006871 name: increased protein phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to ionizing radiation." [PomBase:mah] comment: Also consider annotating to 'increased protein phosphorylation during cellular response to DNA damage' (FYPO:0002095). When using this term, it is recommended to note the specific protein(s) affected. synonym: "increased protein phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth created_by: midori creation_date: 2019-05-08T14:16:31Z [Term] id: FYPO:0006872 name: increased histone H2A phosphorylation during cellular response to ionizing radiation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased." [PomBase:mah] synonym: "increased histone H2A phosphorylation during cellular response to ionizing radiation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H2A phosphorylation during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H2A phosphorylation during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0002596 ! increased histone H2A phosphorylation during vegetative growth created_by: midori creation_date: 2019-05-08T14:56:46Z [Term] id: FYPO:0006873 name: protein mislocalized to cell cortex of cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cell cortex at one or both cell tips is observed there." [PMID:17895368, PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found at the non-growing cell tip in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to cell cortex of cell tip" EXACT [PomBase:vw] synonym: "protein mislocalised to cell cortex of cell tip" EXACT [PomBase:mah] synonym: "protein mislocalised to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cell cortex of cell end" EXACT [PomBase:mah] synonym: "protein mislocalized to cell cortex of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cell tip cortex" EXACT [PomBase:mah] is_a: FYPO:0003527 ! protein mislocalized to cell tip created_by: midori creation_date: 2019-05-08T15:18:03Z [Term] id: FYPO:0006874 name: increased protein localization to cell cortex of old growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex at an old growing cell tip is increased." [PMID:17895368, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell cortex of old growing cell tip" EXACT [GO:0035840, PomBase:mah] synonym: "increased protein localization to cell cortex of old growing cell end" EXACT [PomBase:mah] synonym: "increased protein localization to cell cortex of old growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to cell cortex of old growing cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to old growing cell tip cortex" EXACT [PomBase:mah] is_a: FYPO:0004362 ! increased protein localization to old growing cell tip created_by: midori creation_date: 2019-05-08T15:22:59Z [Term] id: FYPO:0006875 name: abnormal protein localization to cell cortex of cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is abnormal." [PMID:17895368, PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell cortex of cell end during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell cortex of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to cell tip cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth is_a: FYPO:0006867 ! abnormal protein localization to cell cortex created_by: midori creation_date: 2019-05-08T15:38:41Z [Term] id: FYPO:0006876 name: normal protein localization to cell cortex of cell tip def: "A cell phenotype in which the localization of a protein to the cell cortex of the cell tip is normal (i.e. indistinguishable from wild type)." [PMID:29249658, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell cortex of cell tip" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip cortex" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2019-05-08T15:42:18Z [Term] id: FYPO:0006877 name: inviable after spore germination, multiple cell divisions, cell lysis during cytokinesis def: "A phenotype in which a spore germinates to produce an inviable cell that undergoes two or more rounds of cell division, but then lyses during cytokinesis and dies." [PMID:30044717, PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, cytolysis during cytokinesis" EXACT [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, lysed cell during cytokinesis" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, cell lysis during cytokinesis" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, cell lysis during cytokinesis" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, cell lysis during cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0003440 ! cell lysis during cytokinesis is_a: FYPO:0006878 ! inviable after spore germination, multiple cell divisions, with abnormal septation relationship: has_part FYPO:0003440 ! cell lysis during cytokinesis created_by: midori creation_date: 2019-05-13T14:34:19Z [Term] id: FYPO:0006878 name: inviable after spore germination, multiple cell divisions, with abnormal septation def: "A phenotype in which a spore germinates to produce a cell of normal morphology (i.e. size, shape, and structure) that undergoes two or more rounds of cell division in which septum assembly is abnormal, and then dies." [PomBase:mah, PomBase:vw] synonym: "inviable after spore germination, multiple cell divisions, with abnormal septum assembly" EXACT [PomBase:mah] synonym: "inviable after spore germination, multiple cell divisions, with abnormal septum formation" EXACT [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, with abnormal septation" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, with abnormal septation" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, with abnormal septation" EXACT [PomBase:mah] is_a: FYPO:0002430 ! inviable after spore germination, multiple cell divisions created_by: midori creation_date: 2019-05-13T14:42:50Z [Term] id: FYPO:0006879 name: normal cleavage furrow ingression def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cleavage furrow ingression is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cleavage furrow ingression during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cleavage furrow ingression during vegetative growth" EXACT [PomBase:mah] synonym: "normal membrane closure during cytokinesis" RELATED [PomBase:vw] is_a: FYPO:0001367 ! normal cytokinesis created_by: midori creation_date: 2019-05-13T14:47:12Z [Term] id: FYPO:0006880 name: increased protein localization to center of cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the center (as observed end-on) of the site of cell division is increased." [PMID:30044717] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localization to cell division site, protein concentrated at division site center" EXACT [PomBase:vw] synonym: "increased protein localization at division center" EXACT [PMID:30044717] synonym: "increased protein recruitment to center of cell division site" RELATED [PomBase:vw] is_a: FYPO:0001401 ! abnormal protein localization to cell division site created_by: midori creation_date: 2019-05-13T14:48:59Z [Term] id: FYPO:0006881 name: decreased cellular phytoceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phytoceramide measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular phytoceramide level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phytoceramide level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased phytoceramide accumulation" RELATED [PomBase:al] synonym: "reduced cellular phytoceramide level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-05-14T13:33:19Z [Term] id: FYPO:0006882 name: imperforate nuclear envelope def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope is imperforate (i.e. has no openings in the membranes, like wild type)." [PMID:30975915, PomBase:mah] comment: Note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "continuous nuclear envelope" RELATED [PomBase:vw] synonym: "imperforate nuclear envelope during mitotic cell cycle" EXACT [PomBase:mah] synonym: "imperforate nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "imperforate nuclear membrane" NARROW [PomBase:mah] synonym: "normal nuclear integrity" RELATED [PomBase:vw] synonym: "unperforated nuclear envelope" EXACT [PATO:0001821] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth relationship: part_of FYPO:0003751 ! normal nuclear envelope morphology created_by: midori creation_date: 2019-05-14T14:14:12Z [Term] id: FYPO:0006883 name: decreased exocytosis at cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which exocytosis occurs to a lower extent than normal at the cell division site." [PMID:30044717, PomBase:mah] synonym: "decreased exocytosis at cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased exocytosis at cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "reduced exocytosis at cell division site" EXACT [PomBase:mah] is_a: FYPO:0004572 ! decreased exocytosis during vegetative growth created_by: midori creation_date: 2019-06-03T13:31:42Z [Term] id: FYPO:0006884 name: thick mitotic spindle during mitotic metaphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle is thicker than normal during mitotic metaphase." [PMID:30463883, PomBase:mah] comment: In images of thin spindles, polar microtubules may appear not to reach continuously from pole to pole. synonym: "increased mitotic spindle thickness during mitotic metaphase" EXACT [PomBase:mah] synonym: "thick mitotic spindle during mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "thick spindle during mitotic metaphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2019-06-03T14:13:13Z [Term] id: FYPO:0006885 name: decreased protein level at mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured at or associated with the mitotic spindle is lower than normal." [PMID:30463883, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the proteasome is decreased, altering the proteasome stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level at mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level at mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in mitotic spindle" EXACT [PomBase:mah] synonym: "reduced protein level at mitotic spindle" EXACT [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2019-06-03T14:18:36Z [Term] id: FYPO:0006886 name: increased protein level at mitotic spindle def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured at or associated with the mitotic spindle is greater than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein level at mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level at mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level in mitotic spindle" EXACT [PomBase:mah] synonym: "protein accumulation at mitotic spindle" EXACT [PomBase:vw] is_a: FYPO:0000338 ! abnormal mitotic spindle is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2019-06-03T14:20:25Z [Term] id: FYPO:0006887 name: normal protein sumoylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the sumoylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein sumolation during vegetative growth" EXACT [GO:0016925, PomBase:mah] synonym: "normal protein sumoylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2019-06-03T13:55:03Z [Term] id: FYPO:0006888 name: normal protein localization to plasma membrane during iron starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is normal (i.e. indistinguishable from wild type) when the cell is subject to iron ion starvation." [PMID:29549126, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to plasma membrane during iron starvation" EXACT [PomBase:mah] synonym: "normal protein localization to plasma membrane during iron ion starvation" EXACT [PomBase:mah] synonym: "normal protein localization to plasma membrane during iron starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to plasma membrane during iron starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002674 ! normal protein localization to plasma membrane created_by: midori creation_date: 2019-06-03T14:31:34Z [Term] id: FYPO:0006889 name: decreased cellular iron level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ion measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular iron ion level" EXACT [PomBase:mah] synonym: "decreased cellular iron level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular iron level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased iron accumulation" RELATED [PomBase:al] synonym: "reduced cellular iron level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-06-03T14:33:41Z [Term] id: FYPO:0006890 name: decreased heme export from vacuole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of heme export from the vacuole to the cytoplasm is decreased." [PomBase:mah] synonym: "decreased heme export from vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased heme export from vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "heme export from vacuole to cytoplasm" EXACT [GO:0140357] synonym: "reduced heme export from vacuole" EXACT [PomBase:mah] is_a: FYPO:0000598 ! decreased vacuolar transport is_a: FYPO:0001217 ! abnormal nuclear import created_by: midori creation_date: 2019-06-03T14:36:33Z [Term] id: FYPO:0006891 name: abnormal inositol hexakisphosphate kinase activity def: "A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2019-06-03T15:06:32Z [Term] id: FYPO:0006892 name: abolished inositol hexakisphosphate kinase activity def: "A molecular function phenotype in which inositol hexakisphosphate kinase activity is absent." [PomBase:mah] synonym: "inositol hexakisphosphate kinase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0006891 ! abnormal inositol hexakisphosphate kinase activity created_by: midori creation_date: 2019-06-03T15:06:41Z [Term] id: FYPO:0006893 name: decreased inositol hexakisphosphate kinase activity def: "A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is decreased." [PomBase:mah] synonym: "reduced inositol hexakisphosphate kinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0006891 ! abnormal inositol hexakisphosphate kinase activity created_by: midori creation_date: 2019-06-03T15:06:49Z [Term] id: FYPO:0006894 name: increased inositol hexakisphosphate kinase activity def: "A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0006891 ! abnormal inositol hexakisphosphate kinase activity created_by: midori creation_date: 2019-06-03T15:06:56Z [Term] id: FYPO:0006895 name: decreased protein localization to cell tip during meiosis def: "A cell phenotype in which the localization of a protein to the cell tip is decreased during one or both meiotic nuclear divisions." [PMID:30649994, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell tip during meiosis" EXACT [PomBase:mah] synonym: "decreased protein localization to cell end during meiosis" EXACT [PomBase:mah] synonym: "decreased protein localization to cell tip during meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced protein localization to cell tip during meiosis" EXACT [PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0005987 ! abnormal protein localization to cell tip created_by: midori creation_date: 2019-06-03T15:12:29Z [Term] id: FYPO:0006896 name: decreased mitochondrion localization to cell tip during meiosis def: "A cell phenotype in which the localization of mitochondria to the cell tip is decreased during one or both meiotic nuclear divisions." [PMID:30649994, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased mitochondrial localization to cell tip during meiosis" EXACT [PomBase:al] synonym: "decreased mitochondrion localisation to cell tip during meiosis" EXACT [PomBase:mah] synonym: "decreased mitochondrion localization to cell end during meiosis" EXACT [PomBase:mah] synonym: "decreased mitochondrion localization to cell tip during meiotic nuclear division" EXACT [PomBase:mah] synonym: "reduced mitochondrion localization to cell tip during meiosis" EXACT [PomBase:mah] is_a: FYPO:0003549 ! abnormal protein localization during meiosis is_a: FYPO:0005987 ! abnormal protein localization to cell tip created_by: midori creation_date: 2019-06-03T15:20:08Z [Term] id: FYPO:0006897 name: increased rate of actomyosin contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring contraction is increased. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:1902404, PomBase:mah] synonym: "increased rate of actomyosin contractile ring constriction" EXACT [PomBase:mah] synonym: "increased rate of actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of contractile ring contraction" EXACT [PomBase:vw] synonym: "increased rate of cytokinetic contractile ring contraction" EXACT [PomBase:vw] synonym: "increased rate of mitotic actomyosin contractile ring contraction" EXACT [GO:1902404, PomBase:mah] synonym: "increased rate of mitotic contractile ring contraction" EXACT [PomBase:vw] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction is_a: FYPO:0004428 ! increased rate of cytokinesis created_by: midori creation_date: 2019-06-03T15:29:21Z [Term] id: FYPO:0006898 name: normal cell wall thickness during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the thickness of the cell wall is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell wall thickness during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2019-06-03T15:49:02Z [Term] id: FYPO:0006899 name: asymmetric cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormally asymmetric, i.e. cells separate asymmetrically by usually detaching one side of the new ends before the other. Normally, separate symmetrically by detaching both sides of the new ends from each other simultaneously." [PMID:31116668, PomBase:mah] comment: This phenotype usually results from a defect late in septum degradation. synonym: "asymmetric cell separation after cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric cell separation after cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "asymmetric mitotic cytokinetic cell separation" EXACT [GO:0000920] synonym: "asymmetric septum digestion after cytokinesis" EXACT [GO:0000920] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: midori creation_date: 2019-06-03T15:50:21Z [Term] id: FYPO:0006900 name: decreased septum thickness def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is thinner than normal." [PomBase:mah] synonym: "decreased septum thickness during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased septum thickness during vegetative growth" EXACT [PomBase:mah] synonym: "thin septum" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology during vegetative growth created_by: midori creation_date: 2019-06-03T15:57:06Z [Term] id: FYPO:0006901 name: cell deflation and reinflation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cell shrinks temporarily, but then recovers its original size." [PMID:31116668, PomBase:mah] comment: This phenotype usually results from a defect late in septum degradation. synonym: "cell deflation and reinflation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cell deflation and reinflation during vegetative growth" EXACT [PomBase:mah] synonym: "vegetative cell deflation and reinflation" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2019-06-03T15:58:50Z [Term] id: FYPO:0006902 name: loss of viability following cellular response to 4-nitroquinoline N-oxide def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to 4-nitroquinoline N-oxide." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown in the presence of hydroxyurea, and then the number of cells viable enough to form a colony upon hydroxyurea removal is measured and compared to wild type. synonym: "decreased viability following cellular response to 4-nitroquinoline N-oxide" EXACT [PomBase:mah] synonym: "loss of cell population viability following cellular response to 4-nitroquinoline N-oxide" EXACT [PomBase:mah] synonym: "loss of viability following 4-NQO exposure" EXACT [PomBase:mah] synonym: "loss of viability following cellular response to 4-NQO" EXACT [PomBase:mah] synonym: "reduced viability following cellular response to 4-nitroquinoline N-oxide" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2019-06-03T16:03:03Z [Term] id: FYPO:0006903 name: decreased total protein level during mitotic S phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of protein measured in a cell is lower than normal during S phase of the mitotic cell cycle." [PomBase:jh, PomBase:mah] synonym: "decreased total protein accumulation during mitotic S phase" RELATED [PomBase:mah] synonym: "decreased total protein content during mitotic S phase" EXACT [PomBase:jh] synonym: "decreased total protein level during S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced total protein level during mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0006846 ! decreased total protein level during vegetative growth created_by: midori creation_date: 2019-06-10T14:25:34Z [Term] id: FYPO:0006904 name: normal mitotic cell size control checkpoint def: "A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type). A mitotic cell size control checkpoint normally prevents cell cycle progression until the cell reaches a certain size." [GO:0031567, PomBase:mah] synonym: "normal cell size control checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic cell size control checkpoint activation" EXACT [PomBase:mah] synonym: "normal mitotic cell size control checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001703 ! normal mitotic cell cycle checkpoint created_by: midori creation_date: 2019-06-10T14:29:45Z [Term] id: FYPO:0006905 name: normal mitotic G1 cell size control checkpoint def: "A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type). A mitotic cell size control checkpoint normally prevents cell cycle progression from G1 to S phase until the cell reaches a certain size." [GO:0031568, PomBase:mah] synonym: "normal G1 cell size control checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint activation" EXACT [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006904 ! normal mitotic cell size control checkpoint created_by: midori creation_date: 2019-06-10T14:32:06Z [Term] id: FYPO:0006906 name: normal mitotic G2 cell size control checkpoint def: "A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type). A mitotic cell size control checkpoint normally prevents cell cycle progression from G2 to M phase until the cell reaches a certain size." [GO:0031569, PomBase:mah] synonym: "normal G2 cell size control checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitotic G2 cell size control checkpoint activation" EXACT [PomBase:mah] synonym: "normal mitotic G2 cell size control checkpoint during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006904 ! normal mitotic cell size control checkpoint created_by: midori creation_date: 2019-06-10T14:34:31Z [Term] id: FYPO:0006907 name: normal mitotic G1 cell size control checkpoint following nitrogen starvation-induced arrest in G1 phase def: "A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type) when the cell re-enters the mitotic cell cycle following nitrogen starvation-induced arrest in G1 phase. A mitotic cell size control checkpoint normally prevents cell cycle progression from G1 to S phase until the cell reaches a certain size." [GO:0031568, PMID:872890, PomBase:mah] synonym: "normal G1 cell size control checkpoint following nitrogen starvation-induced arrest in G1 phase during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint activation following nitrogen starvation-induced arrest in G1 phase" EXACT [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint following nitrogen starvation-induced arrest in G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint following nitrogen starvation-induced G1 phase arrest" EXACT [PomBase:al] is_a: FYPO:0006905 ! normal mitotic G1 cell size control checkpoint created_by: midori creation_date: 2019-06-10T14:35:47Z [Term] id: FYPO:0006908 name: normal mitotic G1 cell size control checkpoint following spore germination def: "A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type) in the cell cycle following spore germination. A mitotic cell size control checkpoint normally prevents cell cycle progression from G1 to S phase until the cell reaches a certain size." [GO:0031568, PMID:872890, PomBase:mah] synonym: "normal G1 cell size control checkpoint following spore germination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint activation following spore germination" EXACT [PomBase:mah] synonym: "normal mitotic G1 cell size control checkpoint following spore germination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006905 ! normal mitotic G1 cell size control checkpoint created_by: midori creation_date: 2019-06-10T14:59:41Z [Term] id: FYPO:0006909 name: mitotic G1/S phase transition at small cell size def: "A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle occurs at a smaller cell size than normal after the cell has been arrested in G1 phase due to nitrogen starvation. The cell remains arrested in G1." [PMID:872890, PomBase:mah] comment: A G1/S delay may indicate that a checkpoint, such as the cell size checkpoint or the G1/S DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "G1/S phase transition at small cell size during mitotic cell cycle" EXACT [PomBase:mah] synonym: "mitotic G1/S phase transition at abnormally small cell size" EXACT [PomBase:mah] synonym: "mitotic G1/S phase transition at small cell size during vegetative growth" EXACT [PomBase:mah] synonym: "small cell size at G1/S transition of mitotic cell cycle" EXACT [PomBase:al] is_a: FYPO:0000394 ! abnormal mitotic G1/S phase transition created_by: midori creation_date: 2019-06-10T15:02:50Z [Term] id: FYPO:0006910 name: normal growth on vanoxerine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing vanoxerine." [PomBase:mah] synonym: "normal cell population growth in presence of vanoxerine" EXACT [PomBase:mah] synonym: "normal cell population growth on vanoxerine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to vanoxerine" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on vanoxerine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-06-10T15:10:50Z [Term] id: FYPO:0006911 name: normal growth on hexestrol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hexestrol." [PomBase:mah] synonym: "normal cell population growth in presence of hexestrol" EXACT [PomBase:mah] synonym: "normal cell population growth on hexestrol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to hexestrol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on hexestrol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-06-10T15:11:47Z [Term] id: FYPO:0006912 name: normal growth on clomiphene def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing clomiphene." [PomBase:mah] synonym: "normal cell population growth in presence of clomiphene" EXACT [PomBase:mah] synonym: "normal cell population growth on clomiphene" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to clomiphene" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on clomiphene" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-06-10T15:12:23Z [Term] id: FYPO:0006913 name: normal growth on ketoconazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ketoconazole." [PomBase:mah] synonym: "normal cell population growth in presence of ketoconazole" EXACT [PomBase:mah] synonym: "normal cell population growth on ketoconazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to ketoconazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on ketoconazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-06-10T15:13:23Z [Term] id: FYPO:0006914 name: normal growth on terconazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing terconazole." [PomBase:mah] synonym: "normal cell population growth in presence of terconazole" EXACT [PomBase:mah] synonym: "normal cell population growth on terconazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to terconazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on terconazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-06-10T15:16:22Z [Term] id: FYPO:0006915 name: normal cell cycle process def: "A cellular process phenotype in which a cell executes a cell cycle process normally (i.e. indistinguishably from wild type). A cell cycle process is any of the processes that form part of the cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation." [GO:0022402, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0003832 ! normal cell cycle created_by: midori creation_date: 2019-06-10T15:23:05Z [Term] id: FYPO:0006916 name: normal cell cycle phase transition def: "A cellular process phenotype in which a cell executes a cell cycle phase transition normally (i.e. indistinguishably from wild type)." [GO:0044770, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2019-06-10T15:23:15Z [Term] id: FYPO:0006917 name: normal onset of mitotic metaphase/anaphase transition def: "A cellular process phenotype in which the metaphase/anaphase transition of mitosis begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [PomBase:mah] synonym: "normal duration of metaphase during mitosis" RELATED [PomBase:mah] synonym: "normal duration of mitotic metaphase" RELATED [PomBase:mah] synonym: "normal onset of metaphase/anaphase transition of mitotic nuclear division" EXACT [GO:0140014] synonym: "normal timing of mitotic metaphase/anaphase transition" RELATED [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle is_a: FYPO:0006916 ! normal cell cycle phase transition created_by: midori creation_date: 2019-06-10T15:28:46Z [Term] id: FYPO:0006918 name: abolished protein localization to nucleoplasm during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleoplasm during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nucleoplasm during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleoplasm abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0002531 ! abolished protein localization to nucleoplasm is_a: FYPO:0002537 ! abnormal protein localization to nucleoplasm during cellular response to hydroxyurea created_by: midori creation_date: 2019-06-10T15:33:05Z [Term] id: FYPO:0006919 name: normal protein localization to nucleus during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to nucleus during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000838 ! normal protein localization to nucleus during vegetative growth created_by: midori creation_date: 2019-06-10T15:36:53Z [Term] id: FYPO:0006920 name: decreased DNA recombination at mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of DNA recombination at replication fork barriers is decreased." [PMID:28586299, PMID:31149897, PomBase:mah] synonym: "decreased DNA recombination at mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased DNA recombination at mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] synonym: "decreased recombination at mitotic DNA replication fork barriers" EXACT [PomBase:vw] synonym: "reduced DNA recombination at mitotic DNA replication fork barriers" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2019-06-10T15:44:30Z [Term] id: FYPO:0006921 name: decreased gene conversion at mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of gene conversion at replication fork barriers is decreased." [PMID:28586299, PMID:31149897, PomBase:mah] synonym: "decreased gene conversion at mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased gene conversion at mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] synonym: "reduced gene conversion at mitotic DNA replication fork barriers" EXACT [PomBase:mah] is_a: FYPO:0000185 ! decreased gene conversion during vegetative growth is_a: FYPO:0006920 ! decreased DNA recombination at mitotic DNA replication fork barriers created_by: midori creation_date: 2019-06-10T16:12:22Z [Term] id: FYPO:0006922 name: abnormal DNA clamp unloading def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the removal of a sliding clamp such as PCNA from DNA during replication is abnormal." [GO:0090618, PomBase:mah] synonym: "abnormal DNA clamp unloading during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal DNA clamp unloading during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal PCNA unloading" RELATED [GO:0090618] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2019-06-12T16:58:02Z [Term] id: FYPO:0006923 name: normal DNA recombination frequency at mitotic DNA replication fork barriers def: "A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) at DNA replication fork barriers." [PMID:31149897, PomBase:mah] synonym: "normal DNA recombination frequency at mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA recombination frequency at mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-06-12T17:09:51Z [Term] id: FYPO:0006924 name: decreased number of Rad52 foci at mitotic DNA replication fork barriers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates at or near replication fork barriers is lower than normal." [PMID:31149897, PomBase:mah] synonym: "decreased number of Rad22 foci at mitotic DNA replication fork barriers" EXACT [PomBase:mah] synonym: "decreased number of Rad52 foci at mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Rad52 foci at mitotic DNA replication fork barriers during vegetative growth" RELATED [PomBase:mah] synonym: "reduced number of Rad52 foci at mitotic DNA replication fork barriers" EXACT [PomBase:mah] is_a: FYPO:0004516 ! decreased number of Rad52 foci during vegetative growth created_by: midori creation_date: 2019-06-12T17:13:14Z [Term] id: FYPO:0006925 name: decreased number of Rad51 foci at mitotic DNA replication fork barriers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad51 accumulates at or near replication fork barriers is lower than normal." [PMID:31149897, PomBase:mah] synonym: "decreased number of Rad51 foci at mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Rad51 foci at mitotic DNA replication fork barriers during vegetative growth" RELATED [PomBase:mah] synonym: "reduced number of Rad51 foci at mitotic DNA replication fork barriers" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2019-06-12T17:14:48Z [Term] id: FYPO:0006926 name: increased nucleus:cytoplasm ratio def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is greater than normal (the ration observed in wild type is approximately 0.076-0.089)." [PMID:31015410, PomBase:mah] comment: Consider also annotating to 'enlarged nucleus during vegetative growth' (FYPO:0000344). synonym: "increased nuclear:cytoplasmic ratio" EXACT [PomBase:mah] synonym: "increased nuclear:cytoplasmic volume ratio" EXACT [PomBase:mah] synonym: "increased nucleus:cell volume ratio" EXACT [PomBase:mah] synonym: "increased nucleus:cytoplasm ratio during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleus:cytoplasm ratio during vegetative growth" EXACT [PomBase:mah] synonym: "increased nucleus:cytoplasm volume ratio" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2019-06-17T13:16:24Z [Term] id: FYPO:0006927 name: decreased nucleus:cytoplasm ratio def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is lower than normal (the ration observed in wild type is approximately 0.076-0.089)." [PMID:31015410, PomBase:mah] comment: Consider also annotating to 'small nucleus' (FYPO:0000365). synonym: "decreased nuclear:cytoplasmic ratio" EXACT [PomBase:mah] synonym: "decreased nuclear:cytoplasmic volume ratio" EXACT [PomBase:mah] synonym: "decreased nucleus:cell volume ratio" EXACT [PomBase:mah] synonym: "decreased nucleus:cytoplasm ratio during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleus:cytoplasm ratio during vegetative growth" EXACT [PomBase:mah] synonym: "decreased nucleus:cytoplasm volume ratio" EXACT [PomBase:mah] synonym: "reduced nucleus:cytoplasm ratio" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2019-06-17T13:25:25Z [Term] id: FYPO:0006928 name: nuclear membrane blebbing def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or both nuclear membrane(s) form blebs. Membrane blebbing usually leads to decreases in nuclear size and the nucleus:cytoplasm volume ratio." [PMID:31015410, PomBase:mah] synonym: "nuclear envelope blebbing" RELATED [PomBase:mah] synonym: "nuclear membrane blebbing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear membrane blebbing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: midori creation_date: 2019-06-17T13:27:53Z [Term] id: FYPO:0006929 name: sensitive to silver nanoparticles def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to silver nanoparticles. Cells stop growing (and may die) at a concentration of silver nanoparticles that allows wild type cells to grow." [PMID:29294138, PomBase:mah] synonym: "hypersensitive to silver nanoparticles" EXACT [PomBase:mah] synonym: "sensitive to AgNP" EXACT [PMID:29294138] synonym: "sensitive to silver nanoparticles during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to silver nanoparticles during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-06-17T15:04:44Z [Term] id: FYPO:0006930 name: sensitive to butylated hydroxyanisole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to butylated hydroxyanisole (BHA). Cells stop growing (and may die) at a concentration of butylated hydroxyanisole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to butylated hydroxyanisole" EXACT [PomBase:mah] synonym: "sensitive to BHA" EXACT [CHEBI:76359, PomBase:mah] synonym: "sensitive to butylated hydroxyanisole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to butylated hydroxyanisole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-06-17T15:13:09Z [Term] id: FYPO:0006931 name: sensitive to butylated hydroxytoluene def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to butylated hydroxytoluene (dibutylhydroxytoluene; BHT). Cells stop growing (and may die) at a concentration of butylated hydroxytoluene that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to butylated hydroxytoluene" EXACT [PomBase:mah] synonym: "sensitive to 2,6-di-tert-butyl-4-methylphenol" EXACT [CHEBI:34247] synonym: "sensitive to BHT" EXACT [CHEBI:34247, PomBase:mah] synonym: "sensitive to butylated hydroxytoluene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to butylated hydroxytoluene during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to dibutylhydroxytoluene" EXACT [CHEBI:34247] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-06-17T15:13:22Z [Term] id: FYPO:0006932 name: resistance to butylated hydroxyanisole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of butylated hydroxyanisole than normal." [PomBase:mah] synonym: "resistance to BHA" EXACT [CHEBI:76359] synonym: "resistance to butylated hydroxyanisole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to butylated hydroxyanisole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to BHA" EXACT [CHEBI:76359, PomBase:mah] synonym: "resistant to butylated hydroxyanisole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2019-06-17T16:03:27Z [Term] id: FYPO:0006933 name: resistance to butylated hydroxytoluene def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of butylated hydroxytoluene (dibutylhydroxytoluene; BHT) than normal." [PomBase:mah] synonym: "resistance to 2,6-di-tert-butyl-4-methylphenol" EXACT [CHEBI:34247] synonym: "resistance to BHT" EXACT [CHEBI:34247] synonym: "resistance to butylated hydroxytoluene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to butylated hydroxytoluene during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to dibutylhydroxytoluene" EXACT [CHEBI:34247] synonym: "resistant to BHT" EXACT [CHEBI:34247, PomBase:mah] synonym: "resistant to butylated hydroxytoluene" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2019-06-17T16:04:42Z [Term] id: FYPO:0006934 name: normal cellular triglyceride level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular TAG level" EXACT [PomBase:mah] synonym: "normal cellular triacylglycerol level" EXACT [PomBase:mah] synonym: "normal cellular triglyceride accumulation" RELATED [PomBase:mah] synonym: "normal cellular triglyceride level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular triglyceride level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2019-06-24T14:35:40Z [Term] id: FYPO:0006935 name: viable cell with normal cell morphology during nitrogen starvation def: "A cell phenotype in which a cell has normal volume, dimensions and shape, and is viable, when subject to nitrogen starvation." [PomBase:mah] synonym: "small viable spherical cell during nitrogen starvation" EXACT [PomBase:vw] synonym: "viable cell with normal cell morphology during nitrogen depletion" EXACT [PomBase:vw] synonym: "viable cell with normal cell morphology during nitrogen deprivation" EXACT [PomBase:vw] synonym: "viable cell with normal cell shape and size during nitrogen starvation" EXACT [PomBase:vw] synonym: "viable cell with normal morphology during nitrogen starvation" EXACT [PomBase:vw] synonym: "viable orb during nitrogen starvation" EXACT [PomBase:jh, PomBase:vw] synonym: "viable round cells during nitrogen starvation" RELATED [PomBase:mah] synonym: "viable rounded cell during nitrogen starvation" RELATED [PomBase:mah] synonym: "viable rounded cells during nitrogen starvation" RELATED [PomBase:mah] synonym: "viable spherical cell during nitrogen depletion" EXACT [PomBase:vw] synonym: "viable spherical cell during nitrogen deprivation" EXACT [PomBase:vw] synonym: "viable spherical cell during nitrogen starvation" EXACT [PomBase:vw] synonym: "viable spheroid cell during nitrogen depletion" RELATED [PomBase:vw] synonym: "viable spheroid cell during nitrogen deprivation" RELATED [PomBase:vw] synonym: "viable spheroid cell during nitrogen starvation" RELATED [PomBase:vw] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0002048 ! normal cell morphology during nitrogen starvation relationship: has_part FYPO:0002048 ! normal cell morphology during nitrogen starvation created_by: midori creation_date: 2019-06-26T10:28:59Z [Term] id: FYPO:0006936 name: abolished protein localization to plasma membrane at cell division site during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to plasma membrane at cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization in plasma membrane at cell division site during vegetative growth" EXACT [GO:0072659] synonym: "abolished protein localization to cell membrane at cell division site during vegetative growth" EXACT [GO:0005886] synonym: "abolished protein localization to plasma membrane at cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to plasma membrane at cell division site abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002126 ! abolished protein localization to plasma membrane during vegetative growth is_a: FYPO:0005544 ! abnormal protein localization to plasma membrane at cell division site during vegetative growth created_by: midori creation_date: 2019-07-02T14:01:44Z [Term] id: FYPO:0006937 name: abolished lipid binding def: "A molecular function phenotype in which lipid binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "lipid binding abolished" EXACT [PomBase:mah] is_a: FYPO:0007250 ! abnormal lipid binding created_by: midori creation_date: 2019-07-02T14:18:42Z [Term] id: FYPO:0006938 name: actin cables present in increased numbers during cytokinesis def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cables than normal during cytokinesis." [PMID:30709916, PomBase:mah] synonym: "actin cables present in increased numbers during cytokinesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "actin cables present in increased numbers during cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "formin-nucleated actin cables present in increased numbers during cytokinesis" EXACT [GO:0070648, PomBase:mah] synonym: "increased level of actin cables during cytokinesis" RELATED [PomBase:al] synonym: "more actin cables present during cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0006027 ! actin cables present in increased numbers created_by: midori creation_date: 2019-07-02T16:08:32Z [Term] id: FYPO:0006939 name: asymmetric actomyosin contractile ring contraction def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction progresses in a radially asymmetric fashion." [PMID:30709916, PomBase:mah] synonym: "asymmetric actomyosin contractile ring contraction during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric actomyosin contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "non-concentric actomyosin contractile ring contraction" EXACT [PMID:30709916] is_a: FYPO:0001364 ! abnormal actomyosin contractile ring contraction created_by: midori creation_date: 2019-07-02T16:17:38Z [Term] id: FYPO:0006940 name: asymmetric protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is radially asymmetric." [PMID:30709916, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein distribution within the actomyosin contractile ring" RELATED [PomBase:vw] synonym: "asymmetric protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "asymmetric protein localization to actomyosin contractile ring during mitotic cell cycle" RELATED [PomBase:mah] synonym: "asymmetric protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "asymmetric protein recruitment to actomyosin contractile ring" RELATED [PomBase:vw] synonym: "inhomogeneous protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "inhomogeneous protein localization to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "non-homogeneous protein localization to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "uneven protein localization to actomyosin contractile ring" EXACT [PMID:30709916] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring created_by: midori creation_date: 2019-07-02T16:20:40Z [Term] id: FYPO:0006941 name: increased duration of protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to actin cortical patches for a longer time than normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to actin cortical patch" EXACT [PomBase:mah] synonym: "increased duration of protein localization to actin cortical patch during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of protein localization to actin cortical patch involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "increased duration of protein localization to actin patch" EXACT [PomBase:mah] synonym: "increased duration of protein localization to F-actin patch" EXACT [PomBase:mah] is_a: FYPO:0000742 ! abnormal protein localization to actin cortical patch created_by: midori creation_date: 2019-07-02T16:28:46Z [Term] id: FYPO:0006942 name: normal lipid binding def: "A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2019-07-03T15:01:57Z [Term] id: FYPO:0006943 name: normal 3'-5' RNA helicase activity def: "A molecular function phenotype in which the observed rate of an 3'-5' RNA helicase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2019-07-05T11:22:33Z [Term] id: FYPO:0006944 name: decreased ribosomal protein level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount on one or more ribosomal proteins measured in a cell is lower than normal." [PMID:30862564, PomBase:mah] comment: Also consider annotating to 'decreased translation of ribosomal proteins during vegetative growth' (FYPO:0004010), 'increased degradation of ribosomal proteins during vegetative growth' (FYPO:0004011), or both; bear in mind that either can lower the observed level of ribosomal proteins in a cell. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased cellular ribosomal protein level" EXACT [PomBase:mah] synonym: "decreased ribosomal protein level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ribosomal protein level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced ribosomal protein level" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2019-07-08T13:24:14Z [Term] id: FYPO:0006945 name: increased lipid droplet formation def: "A cellular process phenotype in which the occurrence of lipid droplet formation is increased." [PomBase:mah] synonym: "increased lipid droplet assembly" EXACT [PomBase:mah] synonym: "increased lipid particle formation" EXACT [PomBase:mah] is_a: FYPO:0008430 ! abnormal lipid droplet formation relationship: has_output FYPO:0002552 ! lipid droplets present in decreased numbers created_by: midori creation_date: 2019-07-11T14:28:49Z [Term] id: FYPO:0006946 name: inviable swollen elongated multiseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and contains more than one septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] comment: The distinction between this phenotype and centrally constricted (dumbbell-shaped) cells (FYPO:0000779) is that swollen elongated cells do not have a constriction along the long axis. Swollen elongated cells may have a uniform diameter, or may be swollen only around the nucleus. synonym: "inviable large elongated multiseptate vegetative cell" RELATED [PomBase:vw] synonym: "lethal; swollen elongated multiseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001494 ! inviable elongated multiseptate vegetative cell is_a: FYPO:0002845 ! inviable swollen elongated septated vegetative cell is_a: FYPO:0007436 ! swollen elongated multiseptate vegetative cell created_by: midori creation_date: 2019-07-11T14:43:14Z [Term] id: FYPO:0006947 name: protein mislocalized to cytoplasm during glucose starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there when the cell is subject to glucose starvation." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the cytoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "ectopic protein localization to cytoplasm during glucose starvation" EXACT [PomBase:vw] synonym: "protein mislocalised to cytoplasm during glucose starvation" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during glucose depletion" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during glucose deprivation" EXACT [PomBase:mah] is_a: FYPO:0004842 ! protein mislocalized to cytoplasm created_by: midori creation_date: 2019-07-11T14:45:41Z [Term] id: FYPO:0006948 name: normal protein level during glucose starvation def: "A cell phenotype in which the amount of protein measured in a cell that is subject to glucose starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "normal cellular protein level during glucose starvation" EXACT [PomBase:mah] synonym: "normal protein accumulation during glucose starvation" RELATED [PomBase:mah] synonym: "normal protein level during glucose depletion" EXACT [PomBase:vw] synonym: "normal protein level during glucose deprivation" EXACT [PomBase:vw] is_a: FYPO:0004083 ! normal protein level created_by: midori creation_date: 2019-07-11T14:50:00Z [Term] id: FYPO:0006949 name: increased cellular S-methyl-L-ergothioneine level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-methyl-L-ergothioneine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular S-methyl-L-ergothioneine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased S-methyl-L-ergothioneine accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:51:07Z [Term] id: FYPO:0006950 name: increased cellular myo-inositol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of myo-inositol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular myo-inositol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular myo-inositol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased myo-inositol accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:51:39Z [Term] id: FYPO:0006951 name: increased cellular N(alpha),N(alpha)-dimethyl-L-histidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of N(alpha),N(alpha)-dimethyl-L-histidines measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dimethyl-histidine level" EXACT [PomBase:al] synonym: "increased cellular dimethylhistidine level" EXACT [PomBase:mah] synonym: "increased cellular N(alpha),N(alpha)-dimethyl-L-histidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular N(alpha),N(alpha)-dimethyl-L-histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased N(alpha),N(alpha)-dimethyl-L-histidine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:51:55Z [Term] id: FYPO:0006952 name: increased cellular N2-acetyl-L-lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of N2-acetyl-L-lysine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular N2-acetyl-L-lysine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular N2-acetyl-L-lysine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular N2-acetyl-lysine level" EXACT [PomBase:al] synonym: "increased N2-acetyl-L-lysine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:52:20Z [Term] id: FYPO:0006953 name: increased cellular asparagine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased asparagine accumulation" RELATED [PomBase:mah] synonym: "increased cellular asparagine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular asparagine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-asparagine level" EXACT [CHEBI:17196, PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:53:44Z [Term] id: FYPO:0006954 name: increased cellular isoleucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular isoleucine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular isoleucine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-isoleucine level" EXACT [CHEBI:17191, PomBase:al] synonym: "increased isoleucine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:53:47Z [Term] id: FYPO:0006955 name: increased cellular glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-glutamine level" EXACT [CHEBI:18050, PomBase:al] synonym: "increased glutamine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:53:54Z [Term] id: FYPO:0006956 name: increased cellular deferrichrome level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of deferrichrome measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular deferrichrome level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular deferrichrome level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular deferriferrichrome level" EXACT [PomBase:al] synonym: "increased deferrichrome accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:53:57Z [Term] id: FYPO:0006957 name: increased cellular histidinol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidinol measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular histidinol level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular histidinol level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-histidinol level" EXACT [CHEBI:16255] synonym: "increased histidinol accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:54:03Z [Term] id: FYPO:0006958 name: increased cellular 2-oxoglutarate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2-oxoglutarate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased 2-oxoglutarate accumulation" RELATED [PomBase:mah] synonym: "increased cellular 2-oxoglutarate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 2-oxoglutarate level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:54:14Z [Term] id: FYPO:0006959 name: increased cellular succinate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of succinate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular succinate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular succinate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular succinate(2-) level" EXACT [CHEBI:30031] synonym: "increased succinate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:54:19Z [Term] id: FYPO:0006960 name: increased cellular adenosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of adenosine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased adenosine accumulation" RELATED [PomBase:mah] synonym: "increased cellular adenosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular adenosine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:54:31Z [Term] id: FYPO:0006961 name: increased cellular inosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of inosine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular inosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular inosine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased inosine accumulation" RELATED [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:55:06Z [Term] id: FYPO:0006962 name: increased cellular UDP-N-acetylglucosamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP-N-acetylglucosamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular UDP-N-acetyl-alpha-D-glucosamine level" EXACT [CHEBI:16264] synonym: "increased cellular UDP-N-acetylglucosamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular UDP-N-acetylglucosamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased UDP-N-acetylglucosamine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:55:18Z [Term] id: FYPO:0006963 name: increased cellular 1-methyladenosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-methyladenosine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased 1-methyladenosine accumulation" RELATED [PomBase:mah] synonym: "increased cellular 1-methyladenosine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular 1-methyladenosine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:55:23Z [Term] id: FYPO:0006964 name: increased cellular coenzyme A level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme A measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular CoA level" EXACT [PomBase:mah] synonym: "increased cellular coenzyme A level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular coenzyme A level during vegetative growth" EXACT [PomBase:mah] synonym: "increased coenzyme A accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:55:28Z [Term] id: FYPO:0006965 name: increased cellular HMG-CoA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of HMG-CoA measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular 3-hydroxy-3-methylglutaryl-CoA level" EXACT [CHEBI:11814] synonym: "increased cellular HMG-CoA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular HMG-CoA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular hydroxymethylglutaryl-CoA level" EXACT [PomBase:mah] synonym: "increased HMG-CoA accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:55:38Z [Term] id: FYPO:0006966 name: increased cellular acetyl-CoA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of acetyl-CoA measured in a cell is higher than normal." [PomBase:mah] synonym: "increased acetyl-CoA accumulation" RELATED [PomBase:mah] synonym: "increased cellular acetyl-CoA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular acetyl-CoA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T15:55:42Z [Term] id: FYPO:0006967 name: decreased cellular AICAR level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of AICAR measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular AICAR level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular AICAR level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular AICAR level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:02:56Z [Term] id: FYPO:0006968 name: decreased cellular SAICAR level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of SAICAR measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular SAICAR level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular SAICAR level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular SAICAR level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:00Z [Term] id: FYPO:0006969 name: decreased cellular cytidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cytidine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular cytidine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular cytidine level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular cytidine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:05Z [Term] id: FYPO:0006970 name: decreased cellular bisphosphoglyceric acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of bisphosphoglyceric acid measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular bisphosphoglyceric acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular bisphosphoglyceric acid level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular diphosphoglycerate level" RELATED [PomBase:mah] synonym: "decreased level of bisphosphoglyceric acid in cell" EXACT [PomBase:mah] synonym: "reduced cellular bisphosphoglyceric acid level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:12Z [Term] id: FYPO:0006971 name: decreased cellular biotin level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of biotin measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular biotin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular biotin level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular biotin level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:16Z [Term] id: FYPO:0006972 name: decreased cellular S-adenosyl-L-cysteine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-adenosyl-L-cysteine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular S-adenosyl-L-cysteine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular S-adenosyl-L-cysteine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of S-adenosyl-L-cysteine in cell" EXACT [PomBase:mah] synonym: "reduced cellular S-adenosyl-L-cysteine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:20Z [Term] id: FYPO:0006973 name: decreased cellular L-glutamate methyl ester level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate methyl ester measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glutamate methyl ester level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-glutamate methyl ester level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular L-glutamate methyl ester level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular L-glutamate methyl ester level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:24Z [Term] id: FYPO:0006974 name: triglyceride absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is too low to detect." [PomBase:mah] synonym: "TAG absent from cell" EXACT [PomBase:mah] synonym: "triacylglycerol absent from cell" EXACT [PomBase:mah] synonym: "triglyceride absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "triglyceride absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0005585 ! decreased cellular triglyceride level during vegetative growth created_by: midori creation_date: 2019-07-11T16:03:41Z [Term] id: FYPO:0006975 name: RNA absent from cell during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell is too low to detect during the meiotic cell cycle. Total RNA or a specific RNA may be affected." [PomBase:mah] synonym: "transcripts absent from cell during meiotic cell cycle" EXACT [PomBase:vw] synonym: "undetectable cellular RNA level during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001889 ! RNA absent from cell is_a: FYPO:0002959 ! decreased RNA level during meiosis created_by: midori creation_date: 2019-07-12T12:04:48Z [Term] id: FYPO:0006976 name: normal RNA level during meiotic cell cycle def: "A cell phenotype in which the amount of RNA measured in a cell during the meiotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal cellular RNA level during meiotic cell cycle" EXACT [PomBase:mah] synonym: "normal mRNA level during meiotic cell cycle" NARROW [PomBase:mah] synonym: "normal RNA accumulation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcript level during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2019-07-12T12:06:48Z [Term] id: FYPO:0006977 name: abnormal protein ubiquitination def: "A cellular process phenotype in which the ubiquitination of one or more specific proteins, or of specific protein sites, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein ubiquitinylation" RELATED [GO:0016567, PomBase:mah] synonym: "abnormal protein ubiquitylation" EXACT [GO:0016567, PomBase:mah] is_a: FYPO:0002494 ! abnormal protein modification created_by: midori creation_date: 2019-07-12T13:12:43Z [Term] id: FYPO:0006978 name: decreased cellular coenzyme Q10 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular coenzyme Q10 level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular coenzyme Q10 level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular ubiquinone 10 level" EXACT [CHEBI:46245] synonym: "decreased cellular UQ10 level" EXACT [PomBase:al] synonym: "reduced cellular coenzyme Q10 level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-12T13:18:36Z [Term] id: FYPO:0006979 name: increased cellular coenzyme Q10 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in the cell is higher than normal." [PomBase:mah] synonym: "increased cellular coenzyme Q10 level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular coenzyme Q10 level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular ubiquinone 10 level" EXACT [CHEBI:46245] synonym: "increased cellular UQ10 level" EXACT [PomBase:al] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-07-12T13:20:51Z [Term] id: FYPO:0006980 name: increased Glc3Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc3Man9GlcNAc measured in a cell is higher than normal. Glc3Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing three D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:53019, PMID:30389790, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "increased G3M9 glycan accumulation" RELATED [PMID:30389790, PomBase:mah] synonym: "increased G3M9 glycan level" EXACT [PMID:30389790] synonym: "increased Glc3Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "increased Glc3Man9GlcNAc level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased Glc3Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level during vegetative growth created_by: midori creation_date: 2019-07-24T14:11:12Z [Term] id: FYPO:0006981 name: normal cell wall polysaccharide composition during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the levels and proportions of polysaccharides in the cell wall are normal (i.e. indistinguishable from wild type)." [PMID:30389790, PomBase:mah] synonym: "normal cell wall polysaccharide composition during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2019-07-24T14:18:33Z [Term] id: FYPO:0006982 name: normal cell wall morphology during vegetative growth def: "A physical cellular phenotype in which the size, shape, and structure of the cell wall are normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal cell wall morphology during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2019-07-24T14:20:12Z [Term] id: FYPO:0006983 name: abnormal termination of RNA polymerase III transcription def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription RNA polymerase III from a DNA template is abnormal." [GO:0006386, PomBase:mah] synonym: "abnormal RNA polymerase III transcription termination" EXACT [GO:0006386] synonym: "abnormal termination of RNA polymerase III transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal termination of RNA polymerase III transcription during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal transcription termination from Pol III promoter" EXACT [GO:0006386] synonym: "abnormal transcription termination from RNA polymerase III promoter" EXACT [GO:0006386] is_a: FYPO:0003556 ! abnormal transcription termination created_by: midori creation_date: 2019-07-24T14:27:14Z [Term] id: FYPO:0006984 name: increased transcriptional readthrough at RNA polymerase III-transcribed genes def: "A phenotype in which a transcript synthesized on a DNA template by RNA polymerase III is longer than normal due to transcription beyond the normal termination site." [PMID:31294478, PomBase:mah] synonym: "3'-extended transcript at RNA polymerase III-transcribed genes" RELATED [PomBase:mah] synonym: "increased transcript length by 3' extension of RNA polymerase III-transcribed genes" RELATED [PomBase:mah] synonym: "increased transcript length due to transcriptional readthrough at RNA polymerase III-transcribed genes" EXACT [PomBase:mah] synonym: "poly(A) readthrough at RNA polymerase III-transcribed genes" RELATED [PomBase:vw] is_a: FYPO:0003049 ! increased transcriptional readthrough relationship: output_of FYPO:0006983 ! abnormal termination of RNA polymerase III transcription created_by: midori creation_date: 2019-07-24T14:29:42Z [Term] id: FYPO:0006985 name: heterochromatin assembly beyond boundary element IRL def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the silent mating-type cassette than normal, such that it extends beyond the IRL boundary element." [PMID:26518661, PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRL during mitotic cell cycle" RELATED [PomBase:mah] synonym: "heterochromatin assembly beyond boundary element IRL during vegetative growth" EXACT [PomBase:mah] synonym: "heterochromatin formation beyond boundary element IRL" EXACT [PomBase:mah] is_a: FYPO:0007953 ! increased spatial extent of heterochromatin assembly created_by: midori creation_date: 2019-07-30T14:07:39Z [Term] id: FYPO:0006986 name: normal spatial extent of heterochromatin assembly to boundary element IRL def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled up to, but not beyond, the IRL boundary element in the silent mating-type cassette, as in wild type." [PMID:26518661, PomBase:mah] synonym: "normal spatial extent of heterochromatin assembly to boundary element IRL at silent mating type locus" EXACT [PomBase:al] synonym: "normal spatial extent of heterochromatin assembly to boundary element IRL during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spatial extent of heterochromatin assembly to boundary element IRL during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-07-30T14:13:02Z [Term] id: FYPO:0006987 name: increased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased silent mating-type cassette histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth is_a: FYPO:0007373 ! abnormal histone methylation at silent mating-type cassette during vegetative growth created_by: midori creation_date: 2019-07-30T14:19:43Z [Term] id: FYPO:0006988 name: increased histone H3-K9 dimethylation at transposable element during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at transposable elements." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at transposable element during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at transposable element during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at transposon during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation at transposable element during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H3K9me2 at transposable element during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation at transposable element during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2019-07-30T14:27:27Z [Term] id: FYPO:0006989 name: normal histone H3-K9 dimethylation at transposable element during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 is normal (i.e. indistinguishable from wild type) at transposable elements." [PomBase:mah] synonym: "normal histone H3 K9 dimethylation at transposable element during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "normal histone H3-K9 dimethylation at transposable element during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at transposon during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K9 dimethylation at transposable element during vegetative growth" EXACT [PomBase:vw] synonym: "normal histone H3K9me2 at transposable element during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H3 K9 dimethylation at transposable element during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: midori creation_date: 2019-07-30T14:28:32Z [Term] id: FYPO:0006990 name: increased spatial extent of heterochromatin assembly at protein coding gene def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the chromosome than normal in regions containing protein-coding genes." [GO:0031509, PMID:26518661, PomBase:mah] synonym: "heterochromatin spreading at protein coding gene" RELATED [PomBase:mah] synonym: "increased spatial extent of heterochromatin assembly at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spatial extent of heterochromatin assembly at protein coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "increased spatial extent of heterochromatin formation at protein coding gene" EXACT [GO:0031509] is_a: FYPO:0007953 ! increased spatial extent of heterochromatin assembly created_by: midori creation_date: 2019-07-30T14:40:03Z [Term] id: FYPO:0006991 name: normal spatial extent of heterochromatin assembly at protein coding gene def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a normal (i.e. indistinguishable from wild type) portion of the chromosome in regions containing protein-coding genes." [GO:0031509, PMID:26518661, PomBase:mah] synonym: "normal spatial extent of heterochromatin assembly at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spatial extent of heterochromatin assembly at protein coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "normal spatial extent of heterochromatin formation at protein coding gene" EXACT [GO:0031509] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-07-30T14:43:18Z [Term] id: FYPO:0006992 name: normal chromatin silencing at centromere otr1R def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the right outer repeat region (otr1R) of the centromere is normal (i.e. indistinguishable from wild type)." [PMID:26518661, PomBase:mah] comment: Note that the centromere outer repeat region corresponds to SO:0001799. Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "normal centromere outer repeat region chromatin silencing at otr1R" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere otr1R during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at centromere otr1R during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere otr1R region" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromeric otr1R" EXACT [PomBase:mah] synonym: "normal chromatin silencing at pericentric region otr1R" RELATED [PomBase:mah] synonym: "normal chromatin silencing at pericentromeric region otr1R" RELATED [PomBase:mah] synonym: "normal heterochromatic silencing at centromere otr1R" EXACT [PomBase:mah] synonym: "normal heterochromatin silencing at centromere otr1R" EXACT [PomBase:mah] is_a: FYPO:0004742 ! normal chromatin silencing at centromere outer repeat created_by: midori creation_date: 2019-07-30T14:50:50Z [Term] id: FYPO:0006993 name: decreased chromatin silencing at centromere otr1R def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is decreased at the right outer repeat region (otr1R) of the centromere." [PMID:26518661, PomBase:mah] comment: Note that the centromere outer repeat region corresponds to SO:0001799. Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased centromere outer repeat region chromatin silencing at otr1R" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromere otr1R during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at centromere otr1R during vegetative growth" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromere otr1R region" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at centromeric otr1R" EXACT [PomBase:mah] synonym: "decreased chromatin silencing at pericentric region otr1R" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at pericentromeric region otr1R" RELATED [PomBase:mah] synonym: "decreased heterochromatic silencing at centromere otr1R" EXACT [PomBase:mah] synonym: "decreased heterochromatin silencing at centromere otr1R" EXACT [PomBase:mah] synonym: "reduced chromatin silencing at centromere otr1R" EXACT [PomBase:mah] is_a: FYPO:0003412 ! decreased chromatin silencing at centromere outer repeat created_by: midori creation_date: 2019-07-30T14:56:07Z [Term] id: FYPO:0006994 name: increased chromatin silencing at centromere otr1L def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is increased at the left outer repeat region (otr1L) of the centromere." [PMID:26518661, PomBase:mah] comment: Note that the centromere outer repeat region corresponds to SO:0001799. Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "increased centromere outer repeat region chromatin silencing at otr1L" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromere otr1L during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin silencing at centromere otr1L during vegetative growth" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromere otr1L region" EXACT [PomBase:mah] synonym: "increased chromatin silencing at centromeric otr1L" EXACT [PomBase:mah] synonym: "increased chromatin silencing at pericentric region otr1L" RELATED [PomBase:mah] synonym: "increased chromatin silencing at pericentromeric region otr1L" RELATED [PomBase:mah] synonym: "increased heterochromatic silencing at centromere otr1L" EXACT [PomBase:mah] synonym: "increased heterochromatin silencing at centromere otr1L" EXACT [PomBase:mah] is_a: FYPO:0006299 ! increased chromatin silencing at centromere outer repeat created_by: midori creation_date: 2019-07-30T14:57:46Z [Term] id: FYPO:0006995 name: normal chromatin silencing at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "normal chromatin silencing at centromere imr" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "normal chromatin silencing at centromeric inner repeat region" EXACT [PomBase:mah] synonym: "normal heterochromatin silencing at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0002360 ! normal chromatin silencing at centromere created_by: midori creation_date: 2019-07-30T15:02:16Z [Term] id: FYPO:0006996 name: normal antisense RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell normal (i.e. indistinguishable from wild type). Antisense RNA is transcribed from the coding, rather than the template, strand of DNA." [PomBase:mah, SO:0000644] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "normal antisense RNA accumulation" RELATED [PomBase:mah] synonym: "normal antisense RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal antisense RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal antisense RNA transcript level" EXACT [PomBase:vw] synonym: "normal level of antisense transcripts" EXACT [PomBase:al] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2019-07-30T15:14:59Z [Term] id: FYPO:0006997 name: decreased histone exchange at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal at the silent mating-type cassette. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "decreased histone exchange at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone exchange at silent mating-type locus during vegetative growth" EXACT [PomBase:al] synonym: "reduced histone turnover at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] {EXACT="reduced histone exchange at silent mating-type cassette during vegetative growth"} is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth is_a: FYPO:0006356 ! abnormal chromatin remodeling is_a: FYPO:0007472 ! abnormal histone exchange created_by: midori creation_date: 2019-07-30T15:17:23Z [Term] id: FYPO:0006998 name: decreased histone exchange at transposable element during vegetative growth {EXACT="decreased histone exchange at transposable element during vegetative growth"} def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal at transposable elements. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "decreased histone exchange at transposable element during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone exchange at transposon during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone exchange at transposable element during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth is_a: FYPO:0006356 ! abnormal chromatin remodeling is_a: FYPO:0007472 ! abnormal histone exchange created_by: midori creation_date: 2019-07-30T15:19:43Z [Term] id: FYPO:0006999 name: normal dynamic protein localization pattern def: "A cell phenotype in which a protein that is normally dynamically localized to a specific place in the cell shows a normal (i.e. indistinguishable from wild type) temporal pattern of localization. For example, a protein may move to or from the location more or less frequently than normal." [PomBase:mah] subset: qc_do_not_manually_annotate synonym: "normal dynamic pattern of protein localization" EXACT [PomBase:mah] synonym: "normal dynamic protein localisation pattern" EXACT [PomBase:mah] synonym: "normal temporal protein localization pattern" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2019-07-30T15:37:28Z [Term] id: FYPO:0007000 name: normal histone exchange at transposable element def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent at transposable elements. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "normal histone exchange at transposable element during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone exchange at transposable element during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone exchange at transposon" EXACT [PomBase:mah] is_a: FYPO:0006999 ! normal dynamic protein localization pattern created_by: midori creation_date: 2019-07-30T15:37:52Z [Term] id: FYPO:0007001 name: normal histone exchange at pericentric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "normal histone exchange at centromeric heterochromatin" EXACT [GO:0005721] synonym: "normal histone exchange at dh repeat" NARROW [PomBase:al] synonym: "normal histone exchange at pericentric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone exchange at pericentric heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006999 ! normal dynamic protein localization pattern created_by: midori creation_date: 2019-07-30T15:52:26Z [Term] id: FYPO:0007002 name: normal histone exchange at silent mating-type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent at the silent mating-type cassette. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "normal histone exchange at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone exchange at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone exchange at silent mating-type locus" EXACT [PomBase:al] is_a: FYPO:0006999 ! normal dynamic protein localization pattern created_by: midori creation_date: 2019-07-30T15:55:57Z [Term] id: FYPO:0007003 name: normal histone exchange at tRNA genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent at tRNA genes. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "normal histone exchange at transfer RNA genes" EXACT [PomBase:mah] synonym: "normal histone exchange at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone exchange at tRNA genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006999 ! normal dynamic protein localization pattern created_by: midori creation_date: 2019-07-30T15:57:02Z [Term] id: FYPO:0007004 name: decreased histone exchange at protein coding gene during vegetative growth {EXACT="decreased histone exchange at protein coding gene during vegetative growth"} def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal in regions containing protein coding genes. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0005721, GO:0043486, PMID:26518661, PomBase:mah] synonym: "decreased histone exchange at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone exchange at protein coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth is_a: FYPO:0006356 ! abnormal chromatin remodeling is_a: FYPO:0007472 ! abnormal histone exchange created_by: midori creation_date: 2019-07-30T15:57:56Z [Term] id: FYPO:0007005 name: decreased DNA recombination downstream of mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of DNA recombination downstream of replication fork barriers is decreased." [PMID:30667359, PomBase:mah] synonym: "decreased DNA recombination downstream of mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased DNA recombination downstream of mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] synonym: "decreased recombination downstream of mitotic DNA replication fork barriers" EXACT [PomBase:vw] synonym: "decreased template switching recombination downstream of mitotic DNA replication fork barriers" EXACT [PMID:30667359] synonym: "reduced DNA recombination downstream of mitotic DNA replication fork barriers" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2019-07-30T16:12:47Z [Term] id: FYPO:0007006 name: increased DNA recombination downstream of mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of DNA recombination downstream of replication fork barriers is increased." [PMID:30667359, PomBase:mah] synonym: "increased DNA recombination downstream of mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA recombination downstream of mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] synonym: "increased recombination downstream of mitotic DNA replication fork barriers" EXACT [PomBase:vw] synonym: "increased template switching recombination downstream of mitotic DNA replication fork barriers" EXACT [PMID:30667359] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2019-07-30T16:27:30Z [Term] id: FYPO:0007007 name: normal DNA recombination frequency downstream of mitotic DNA replication fork barriers def: "A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) downstream of DNA replication fork barriers." [PMID:30667359, PomBase:mah] synonym: "normal DNA recombination frequency downstream of mitotic DNA replication fork barriers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA recombination frequency downstream of mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] synonym: "normal template switching recombination frequency downstream of mitotic DNA replication fork barriers" EXACT [PMID:30667359] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-07-30T16:31:28Z [Term] id: FYPO:0007008 name: normal termination of RNA polymerase III transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase III is normal (i.e. indistinguishable from wild type)." [GO:0006386, PomBase:mah] synonym: "normal RNA polymerase III transcription termination" EXACT [GO:0006386] synonym: "normal termination of RNA polymerase III transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal termination of RNA polymerase III transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0000859 ! normal metabolic process during vegetative growth is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2019-07-31T11:34:06Z [Term] id: FYPO:0007009 name: decreased heterochromatin assembly by small RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is decreased." [PomBase:mah] synonym: "decreased chromatin silencing by small RNA" EXACT [PomBase:mah] synonym: "decreased heterochromatin assembly by small RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased heterochromatin assembly by small RNA during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNAi-mediated chromatin silencing" EXACT [PomBase:al] synonym: "reduced heterochromatin assembly by small RNA" EXACT [PomBase:mah] is_a: FYPO:0000187 ! abnormal heterochromatin assembly by small RNA is_a: FYPO:0006356 ! abnormal chromatin remodeling created_by: midori creation_date: 2019-07-31T11:52:29Z [Term] id: FYPO:0007010 name: secondary siRNA absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of secondary siRNA measured in a cell is too low to detect. Secondary siRNAs are sequences homologous to regions 5' and 3' to the initial siRNA, and their production amplifies the primary siRNA signal." [PMID:20062003, PMID:22542102, PomBase:al, PomBase:mah] synonym: "secondary siRNA absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "secondary siRNA absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "secondary small interfering RNA absent from cell" EXACT [PomBase:mah] is_a: FYPO:0006076 ! siRNA absent from cell created_by: midori creation_date: 2019-07-31T12:03:41Z [Term] id: FYPO:0007011 name: increased protein localization to chromatin at ncRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA genes is increased." [PMID:31294478, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at ncRNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at ncRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at ncRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at non-coding RNA genes" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2019-07-31T13:12:14Z [Term] id: FYPO:0007012 name: normal mature 28S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 28S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 28S rRNA level" BROAD [PomBase:mah] synonym: "normal mature 28S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature 28S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature 28S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature 28S rRNA transcript level" EXACT [PomBase:mah] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2019-07-31T13:20:05Z [Term] id: FYPO:0007013 name: normal mature 5S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 5S rRNA level" BROAD [PomBase:mah] synonym: "normal mature 5S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature 5S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature 5S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature 5S rRNA transcript level" EXACT [PomBase:mah] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2019-07-31T13:43:43Z [Term] id: FYPO:0007014 name: normal mature 5.8S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5.8S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 5.8S rRNA level" BROAD [PomBase:mah] synonym: "normal mature 5.8S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal mature 5.8S rRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mature 5.8S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mature 5.8S rRNA transcript level" EXACT [PomBase:mah] is_a: FYPO:0006000 ! normal rRNA or precursor level created_by: midori creation_date: 2019-07-31T13:45:12Z [Term] id: FYPO:0007015 name: increased protein localization to chromatin at 3' end of tRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the 3' ends of tRNA genes is increased." [PMID:31294478, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at 3' end of tRNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of transfer RNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of tRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at tRNA genes at 3' end" EXACT [PomBase:mah] is_a: FYPO:0004033 ! increased protein localization to chromatin at tRNA genes is_a: FYPO:0007734 ! increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes created_by: midori creation_date: 2019-07-31T13:56:35Z [Term] id: FYPO:0007016 name: increased protein localization to chromatin at 3' end of rRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the 3' ends of rRNA genes in ribosomal DNA repeat regions is increased." [PMID:31294478, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at 3' end of rRNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of ribosomal RNA genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of rRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of rRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at rRNA genes at 3' end" EXACT [PomBase:mah] is_a: FYPO:0004032 ! increased protein localization to chromatin at rDNA is_a: FYPO:0007733 ! abnormal protein localization to chromatin at 3' end of genes created_by: midori creation_date: 2019-07-31T14:06:50Z [Term] id: FYPO:0007017 name: normal tRNA pseudouridylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA pseudouridylation, the intramolecular conversion of uridine to pseudouridine in a tRNA molecule, is normal (i.e. indistinguishable from wild type)." [GO:0031119, PomBase:mah] synonym: "normal pseudouridine level in tRNA" RELATED [PomBase:vw] synonym: "normal tRNA pseudouridine synthesis" EXACT [GO:0031119] synonym: "normal tRNA pseudouridylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA pseudouridylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001762 ! normal tRNA modification created_by: midori creation_date: 2019-07-31T14:36:42Z [Term] id: FYPO:0007018 name: normal tRNA guanosine 2'-O-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 2'-O-methylguanosine is normal (i.e. indistinguishable from wild type)." [http://modomics.genesilico.pl/modifications/Gm/, PMID:25404562, PomBase:mah] synonym: "normal 2'-O-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "normal tRNA 2'-O-methylguanosine formation" EXACT [PomBase:mah] synonym: "normal tRNA Gm formation" EXACT [http://modomics.genesilico.pl/modifications/Gm/] synonym: "normal tRNA guanosine 2'-O-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA guanosine 2'-O-methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001763 ! normal tRNA methylation created_by: midori creation_date: 2019-07-31T14:44:15Z [Term] id: FYPO:0007019 name: normal tRNA guanosine 7-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 7-methylguanosine is normal (i.e. indistinguishable from wild type)." [http://modomics.genesilico.pl/modifications/m7G/, PMID:25404562, PomBase:mah] synonym: "normal 7-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "normal tRNA 7-methylguanosine formation" EXACT [PomBase:mah] synonym: "normal tRNA guanosine 7-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA guanosine 7-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal tRNA m7G formation" EXACT [http://modomics.genesilico.pl/modifications/m7G/] is_a: FYPO:0001763 ! normal tRNA methylation created_by: midori creation_date: 2019-07-31T15:00:40Z [Term] id: FYPO:0007020 name: normal tRNA guanosine N2-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form N2-methylguanosine is normal (i.e. indistinguishable from wild type)." [http://modomics.genesilico.pl/modifications/m2G/, PMID:25404562, PomBase:mah] synonym: "normal N2-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "normal tRNA guanosine N2-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal tRNA guanosine N2-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal tRNA m2G formation" EXACT [http://modomics.genesilico.pl/modifications/m2G/] synonym: "normal tRNA N2-methylguanosine formation" EXACT [PomBase:mah] is_a: FYPO:0001763 ! normal tRNA methylation created_by: midori creation_date: 2019-07-31T15:06:01Z [Term] id: FYPO:0007021 name: abolished tRNA cytosine 2'-O-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a cytosine residue in a tRNA molecule to form 2'-O-methylcytidine does not occur." [http://modomics.genesilico.pl/modifications/Cm/, PMID:25404562, PomBase:mah] synonym: "2'-O-methylcytidine absent from tRNA" RELATED [PomBase:vw] synonym: "abolished tRNA 2'-O-methylcytidine formation" EXACT [PomBase:mah] synonym: "abolished tRNA Cm formation" EXACT [http://modomics.genesilico.pl/modifications/Cm/] synonym: "abolished tRNA cytosine 2'-O-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA cytosine 2'-O-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "tRNA cytosine 2'-O-methylation abolished" RELATED [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2019-07-31T15:23:20Z [Term] id: FYPO:0007022 name: abolished tRNA guanosine 2'-O-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 2'-O-methylguanosine does not occur." [http://modomics.genesilico.pl/modifications/Gm/, PMID:25404562, PomBase:mah] synonym: "2'-O-methylguanosine absent from tRNA" RELATED [PomBase:vw] synonym: "abolished tRNA 2'-O-methylguanosine formation" EXACT [PomBase:mah] synonym: "abolished tRNA Gm formation" EXACT [http://modomics.genesilico.pl/modifications/Gm/] synonym: "abolished tRNA guanosine 2'-O-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA guanosine 2'-O-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "tRNA guanosine 2'-O-methylation abolished" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2019-07-31T15:29:03Z [Term] id: FYPO:0007023 name: increased tRNA guanosine 1-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 1-methylguanosine occurs to a greater extent than normal." [http://modomics.genesilico.pl/modifications/m1G/, PMID:25404562, PomBase:mah] synonym: "increased 1-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "increased guanosine N1-methylation" EXACT [PomBase:mah] synonym: "increased tRNA 1-methylguanosine formation" EXACT [PomBase:mah] synonym: "increased tRNA guanosine 1-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased tRNA guanosine 1-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased tRNA m1G formation" EXACT [http://modomics.genesilico.pl/modifications/m1G/] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2019-07-31T15:30:31Z [Term] id: FYPO:0007024 name: decreased tRNA guanosine 7-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 7-methylguanosine occurs to a lower extent than normal." [http://modomics.genesilico.pl/modifications/m7G/, PMID:25404562, PomBase:mah] synonym: "decreased 7-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "decreased tRNA 7-methylguanosine formation" EXACT [PomBase:mah] synonym: "decreased tRNA guanosine 7-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tRNA guanosine 7-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tRNA m7G formation" EXACT [http://modomics.genesilico.pl/modifications/m7G/] synonym: "reduced tRNA guanosine 7-methylation" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2019-07-31T15:36:27Z [Term] id: FYPO:0007025 name: decreased tRNA guanosine N2-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form N2-methylguanosine occurs to a lower extent than normal." [http://modomics.genesilico.pl/modifications/m2G/, PMID:25404562, PomBase:mah] synonym: "decreased N2-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "decreased tRNA guanosine N2-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tRNA guanosine N2-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tRNA m2G formation" EXACT [http://modomics.genesilico.pl/modifications/m2G/] synonym: "decreased tRNA N2-methylguanosine formation" EXACT [PomBase:mah] synonym: "reduced tRNA guanosine N2-methylation" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation created_by: midori creation_date: 2019-07-31T15:36:38Z [Term] id: FYPO:0007026 name: decreased tRNA wybutosine biosynthesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional modification of a guanosine residue in a tRNA molecule to form wybutosine occurs to a lower extent than normal." [http://modomics.genesilico.pl/modifications/yW/, PMID:25404562, PomBase:mah] synonym: "decreased tRNA wybutosine biosynthesis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased tRNA wybutosine biosynthesis during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tRNA wybutosine biosynthetic process" EXACT [GO:0031591] synonym: "decreased tRNA wybutosine formation" EXACT [PomBase:mah] synonym: "decreased tRNA yW formation" EXACT [http://modomics.genesilico.pl/modifications/yW/] synonym: "decreased wybutosine level in tRNA" RELATED [PomBase:vw] synonym: "reduced tRNA wybutosine biosynthesis" EXACT [PomBase:mah] is_a: FYPO:0001765 ! abnormal tRNA modification created_by: midori creation_date: 2019-07-31T15:40:18Z [Term] id: FYPO:0007027 name: abolished protein localization to medial cortex, with protein mislocalized to cytoplasm, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex is abolished, and the protein is present in the cytoplasm instead." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortex, with protein mislocalised to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortex, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to medial ring, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [GO:0031097] synonym: "protein localization to medial cortex abolished, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0002555 ! abolished protein localization to medial cortex during vegetative growth relationship: has_part FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth created_by: midori creation_date: 2019-07-31T15:55:26Z [Term] id: FYPO:0007028 name: normal protein localization to medial cortex septin ring during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring at the medial cortex is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to medial cortex septin ring during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to medial cortex septin ring during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2019-08-05T13:21:07Z [Term] id: FYPO:0007029 name: decreased protein localization to polysome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to polysomes is decreased." [PMID:31285271, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to polysome" EXACT [PomBase:mah] synonym: "decreased protein localization to polyribosome" EXACT [PomBase:mah] synonym: "decreased protein localization to polysome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to polysome during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to polysome" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2019-08-05T13:49:42Z [Term] id: FYPO:0007030 name: normal cell wall monosaccharide composition during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the levels and proportions of monosaccharides in the cell wall are normal (i.e. indistinguishable from wild type)." [PMID:30389790, PomBase:mah] synonym: "normal cell wall monosaccharide composition during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2019-08-05T13:52:32Z [Term] id: FYPO:0007031 name: abolished protein localization to cell cortex of cell tip during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips does not occur during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell cortex of cell tip during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cell cortex of cell end during mitotic interphase during vegetative growth" RELATED [PomBase:mah] synonym: "abolished protein localization to cell cortex of cell tip during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip cortex during mitotic interphase" EXACT [PomBase:mah] synonym: "protein localization to cell cortex of cell tip abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0006502 ! abolished protein localization to cell cortex of cell tip during vegetative growth is_a: FYPO:0006875 ! abnormal protein localization to cell cortex of cell tip during vegetative growth created_by: midori creation_date: 2019-08-05T13:55:19Z [Term] id: FYPO:0007032 name: increased protein glycosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the glycosylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid." [GO:0006486, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein glycosylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein hyperglycosylation during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001910 ! abnormal protein glycosylation during vegetative growth created_by: midori creation_date: 2019-08-05T14:47:17Z [Term] id: FYPO:0007033 name: resistance to fluconazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of fluconazole than normal." [PomBase:mah] synonym: "resistance to fluconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to fluconazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to fluconazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2019-08-12T11:30:18Z [Term] id: FYPO:0007034 name: resistance to phenylglyoxal def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phenylglyoxal than normal." [PomBase:mah] synonym: "resistance to 2-oxo-2-phenylacetaldehyde" EXACT [CHEBI:88868] synonym: "resistance to phenylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to phenylglyoxal during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to phenylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2019-08-12T11:32:16Z [Term] id: FYPO:0007035 name: normal growth on 5-fluorouracil def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 5-fluorouracil." [PomBase:mah] synonym: "normal cell population growth in presence of 5-fluorouracil" EXACT [PomBase:mah] synonym: "normal cell population growth on 5-fluorouracil" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on 5-FU" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on 5-fluorouracil" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-08-12T11:34:47Z [Term] id: FYPO:0007036 name: normal growth on phenylglyoxal def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing phenylglyoxal." [PomBase:mah] synonym: "normal cell population growth in presence of phenylglyoxal" EXACT [PomBase:mah] synonym: "normal cell population growth on 2-oxo-2-phenylacetaldehyde" EXACT [CHEBI:88868] synonym: "normal cell population growth on phenylglyoxal" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on phenylglyoxal" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-08-12T11:35:29Z [Term] id: FYPO:0007037 name: sensitive to phenylglyoxal def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phenylglyoxal. Cells stop growing (and may die) at a concentration of phenylglyoxal that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to phenylglyoxal" EXACT [PomBase:mah] synonym: "sensitive to 2-oxo-2-phenylacetaldehyde" EXACT [CHEBI:88868] synonym: "sensitive to phenylglyoxal during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to phenylglyoxal during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-08-12T11:36:59Z [Term] id: FYPO:0007038 name: decreased protein localization to mitochondrion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitochondrion" EXACT [PomBase:mah] synonym: "decreased protein localization to mitochondrion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to mitochondrion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitochondrion" EXACT [PomBase:mah] is_a: FYPO:0004336 ! abnormal protein localization to mitochondrion created_by: midori creation_date: 2019-08-12T11:40:52Z [Term] id: FYPO:0007039 name: decreased protein localization to mitochondrion, with protein mislocalized to cytoplasmic foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is decreased, and the protein is instead visible in one or a few foci or dots in the cytoplasm." [PMID:30181366, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitochondrion, with protein mislocalised to cytoplasmic foci" EXACT [PomBase:mah] synonym: "decreased protein localization to mitochondrion, with protein mislocalized to cytoplasmic foci, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007038 ! decreased protein localization to mitochondrion created_by: midori creation_date: 2019-08-12T11:41:38Z [Term] id: FYPO:0007040 name: abnormal alkaline phosphatase activity def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2019-08-14T11:06:11Z [Term] id: FYPO:0007041 name: increased alkaline phosphatase activity def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0007040 ! abnormal alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:09:28Z [Term] id: FYPO:0007042 name: decreased alkaline phosphatase activity def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is decreased." [PomBase:mah] synonym: "reduced alkaline phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0007040 ! abnormal alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:09:28Z [Term] id: FYPO:0007043 name: abolished alkaline phosphatase activity def: "A molecular function phenotype in which alkaline phosphatase activity is absent." [PomBase:mah] synonym: "alkaline phosphatase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0007040 ! abnormal alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:09:28Z [Term] id: FYPO:0007044 name: decreased alkaline phosphatase activity during stress response to zinc ion def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is decreased during a cellular stress response to zinc ions." [PomBase:mah] synonym: "decreased alkaline phosphatase activity during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "decreased alkaline phosphatase activity during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "decreased alkaline phosphatase activity during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "decreased alkaline phosphatase activity during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "decreased alkaline phosphatase activity during response to zinc ion stress" EXACT [GO:1990359] synonym: "decreased alkaline phosphatase activity during response to zinc toxicity" RELATED [GO:1990359] synonym: "decreased alkaline phosphatase activity during stress response to zinc" BROAD [GO:1990359] synonym: "reduced alkaline phosphatase activity during stress response to zinc ion" EXACT [PomBase:mah] is_a: FYPO:0007042 ! decreased alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:09:50Z [Term] id: FYPO:0007045 name: decreased alkaline phosphatase activity during cellular response to zinc ion starvation def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is decreased during a cellular response to zinc ion starvation." [PomBase:mah] synonym: "decreased alkaline phosphatase activity during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "decreased alkaline phosphatase activity during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "decreased alkaline phosphatase activity during cellular response to zinc ion limitation" EXACT [PomBase:vw] synonym: "decreased alkaline phosphatase activity during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "reduced alkaline phosphatase activity during cellular response to zinc ion starvation" EXACT [PomBase:mah] is_a: FYPO:0007042 ! decreased alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:09:52Z [Term] id: FYPO:0007046 name: abolished alkaline phosphatase activity during cellular response to zinc ion starvation def: "A molecular function phenotype in which alkaline phosphatase activity is absent during a cellular response to zinc ion starvation." [PomBase:mah] synonym: "abolished alkaline phosphatase activity during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "abolished alkaline phosphatase activity during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "abolished alkaline phosphatase activity during cellular response to zinc ion limitation" EXACT [PomBase:vw] synonym: "abolished alkaline phosphatase activity during cellular response to zinc starvation" EXACT [PomBase:mah] synonym: "alkaline phosphatase activity abolished during cellular response to zinc ion starvation" EXACT [PomBase:mah] is_a: FYPO:0007043 ! abolished alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:10:03Z [Term] id: FYPO:0007047 name: normal alkaline phosphatase activity def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2019-08-14T11:18:19Z [Term] id: FYPO:0007048 name: normal alkaline phosphatase activity during stress response to zinc ion def: "A molecular function phenotype in which the observed rate of alkaline phosphatase activity is normal (i.e. indistinguishable from wild type) during a cellular stress response to zinc ions." [PomBase:mah] synonym: "normal alkaline phosphatase activity during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "normal alkaline phosphatase activity during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "normal alkaline phosphatase activity during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "normal alkaline phosphatase activity during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "normal alkaline phosphatase activity during response to zinc ion stress" EXACT [GO:1990359] synonym: "normal alkaline phosphatase activity during response to zinc toxicity" RELATED [GO:1990359] synonym: "normal alkaline phosphatase activity during stress response to zinc" BROAD [GO:1990359] is_a: FYPO:0007047 ! normal alkaline phosphatase activity created_by: midori creation_date: 2019-08-14T11:19:09Z [Term] id: FYPO:0007049 name: decreased RNA level during stress response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular stress response to zinc ions is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during stress response to zinc ion" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during stress response to zinc ion" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "decreased RNA level during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "decreased RNA level during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "decreased RNA level during response to zinc ion stress" EXACT [GO:1990359] synonym: "decreased RNA level during response to zinc toxicity" RELATED [GO:1990359] synonym: "decreased RNA level during stress response to zinc" EXACT [PomBase:mah] synonym: "decreased RNA level during stress response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during stress response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased transcript level during stress response to zinc ion" EXACT [PomBase:vw] synonym: "reduced RNA level during stress response to zinc ion" EXACT [PomBase:mah] is_a: FYPO:0001546 ! decreased RNA level during cellular response to zinc ion created_by: midori creation_date: 2019-08-14T11:40:00Z [Term] id: FYPO:0007050 name: increased RNA level during stress response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular stress response to zinc ions is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during stress response to zinc ion" NARROW [PomBase:mah] synonym: "increased RNA accumulation during stress response to zinc ion" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "increased RNA level during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "increased RNA level during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "increased RNA level during response to zinc ion stress" EXACT [GO:1990359] synonym: "increased RNA level during response to zinc toxicity" RELATED [GO:1990359] synonym: "increased RNA level during stress response to zinc" EXACT [PomBase:mah] synonym: "increased RNA level during stress response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during stress response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcript level during stress response to zinc ion" EXACT [PomBase:vw] is_a: FYPO:0005291 ! increased RNA level during cellular response to zinc ion created_by: midori creation_date: 2019-08-14T11:42:18Z [Term] id: FYPO:0007051 name: altered protein level during stress response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular stress response to zinc ions. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein level during stress response to zinc ion" EXACT [PomBase:mah] synonym: "altered cellular protein level during stress response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "altered protein level during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "altered protein level during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "altered protein level during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "altered protein level during response to zinc ion stress" EXACT [GO:1990359] synonym: "altered protein level during response to zinc toxicity" RELATED [GO:1990359] synonym: "altered protein level during stress response to zinc" EXACT [PomBase:mah] synonym: "altered protein level during stress response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001550 ! altered protein level during cellular response to zinc ion created_by: midori creation_date: 2019-08-14T11:44:44Z [Term] id: FYPO:0007052 name: increased protein level during stress response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular stress response to zinc ions is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased protein accumulation during stress response to zinc ion" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "increased protein level during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "increased protein level during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "increased protein level during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "increased protein level during response to zinc ion stress" EXACT [GO:1990359] synonym: "increased protein level during response to zinc toxicity" RELATED [GO:1990359] synonym: "increased protein level during stress response to zinc" EXACT [PomBase:mah] synonym: "increased protein level during stress response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein level during stress response to zinc ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0007051 ! altered protein level during stress response to zinc ion created_by: midori creation_date: 2019-08-14T11:46:57Z [Term] id: FYPO:0007053 name: decreased protein level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "decreased protein level during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "decreased protein level during cellular response to zinc ion limitation" EXACT [PomBase:vw] synonym: "decreased protein level during cellular response to zinc ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to zinc starvation" EXACT [GO:0071453] synonym: "reduced protein level during cellular response to zinc ion starvation" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth created_by: midori creation_date: 2019-08-14T11:49:36Z [Term] id: FYPO:0007054 name: normal protein level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to zinc ion depletion" EXACT [PomBase:vw] synonym: "normal protein level during cellular response to zinc ion deprivation" EXACT [PomBase:vw] synonym: "normal protein level during cellular response to zinc ion limitation" EXACT [PomBase:vw] synonym: "normal protein level during cellular response to zinc ion starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to zinc starvation" EXACT [PomBase:mah] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: midori creation_date: 2019-08-14T11:51:00Z [Term] id: FYPO:0007055 name: normal endosome organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endosome organization is normal (i.e. indistinguishable from wild type)." [GO:0007032, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal endosome organisation" EXACT [PomBase:mah] synonym: "normal endosome organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0006003 ! normal cellular component organization created_by: midori creation_date: 2019-08-14T13:07:07Z [Term] id: FYPO:0007056 name: abnormal post-Golgi vesicle-mediated transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of substances via vesicles from the Golgi to other parts of the cell is abnormal.." [GO:0006892, PomBase:mah] synonym: "abnormal exit from TGN" EXACT [PomBase:vw] synonym: "abnormal post-Golgi transport" EXACT [GO:0006892] synonym: "abnormal post-Golgi vesicle-mediated transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal post-Golgi vesicle-mediated transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport during vegetative growth created_by: midori creation_date: 2019-08-14T13:10:52Z [Term] id: FYPO:0007057 name: abnormal recycling endosome to Golgi transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of substances via vesicles from recycling endosomes to the Golgi is abnormal." [GO:0071955, PomBase:mah] synonym: "abnormal recycling endosome to Golgi transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal recycling endosome to Golgi transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport during vegetative growth created_by: midori creation_date: 2019-08-14T13:14:01Z [Term] id: FYPO:0007058 name: normal protein localization to vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to vacuole" EXACT [PomBase:mah] synonym: "normal protein localization in vacuole" EXACT [PomBase:mah] synonym: "normal protein localization to vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to vacuole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2019-08-14T13:16:00Z [Term] id: FYPO:0007059 name: decreased protein localization to late endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes is decreased." [PMID:31341193, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to late endosome" EXACT [PomBase:mah] synonym: "decreased protein localization to late endosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to late endosome during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to prevacuolar compartment" EXACT [GO:0005770] synonym: "decreased protein localization to prevacuolar endosome" EXACT [PomBase:vw] synonym: "decreased protein localization to PVE" EXACT [PomBase:vw] synonym: "reduced protein localization to late endosome" EXACT [PomBase:mah] is_a: FYPO:0007587 ! abnormal protein localization to endosome created_by: midori creation_date: 2019-08-14T13:35:22Z [Term] id: FYPO:0007060 name: decreased actin filament depolymerization involved in actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament polymerization, i.e. the addition of actin monomers to a filament, occurs to a lower extent than normal as part of contractile ring assembly during cytokinesis." [PomBase:mah] synonym: "decreased actin filament depolymerisation involved in actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "decreased actin filament depolymerization involved in actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased actin filament depolymerization involved in actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased actin filament depolymerization involved in mitotic actomyosin contractile ring assembly" EXACT [GO:1903475] synonym: "reduced actin filament depolymerization involved in actomyosin contractile ring assembly" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization during vegetative growth created_by: midori creation_date: 2019-08-14T15:37:09Z [Term] id: FYPO:0007061 name: normal Arp2/3 complex-mediated actin nucleation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin monomers associate to form a new branch on the side of an existing actin filament, mediated by the Arp2/3 protein complex, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin filament branch nucleation" EXACT [GO:0034314] synonym: "normal Arp2/3 complex-mediated actin filament nucleation" EXACT [PomBase:mah] synonym: "normal Arp2/3 complex-mediated actin nucleation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal Arp2/3 complex-mediated actin nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "normal branched actin filament nucleation" EXACT [GO:0034314] is_a: FYPO:0001366 ! normal actin cytoskeleton organization created_by: midori creation_date: 2019-08-14T15:40:43Z [Term] id: FYPO:0007062 name: decreased Atg1/ULK1 kinase complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of Atg1/ULK1 kinase complex assembly is decreased." [PomBase:mah] synonym: "decreased Atg1/ULK1 kinase complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Atg1/ULK1 kinase11 complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced Atg1/ULK1 kinase complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2019-08-19T15:02:35Z [Term] id: FYPO:0007063 name: increased 23S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 23S rRNA precursor measured in a cell is higher than normal." [PMID:29641590, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 23S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased 23S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased 23S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased 23S rRNA precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0003600 ! increased rRNA precursor level created_by: midori creation_date: 2019-08-19T15:12:00Z [Term] id: FYPO:0007064 name: increased 22S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 22S rRNA precursor measured in a cell is higher than normal." [PMID:29641590, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 22S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased 22S rRNA precursor level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased 22S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased 22S rRNA precursor transcript level" EXACT [PomBase:vw] is_a: FYPO:0003600 ! increased rRNA precursor level created_by: midori creation_date: 2019-08-19T15:14:18Z [Term] id: FYPO:0007065 name: 20S rRNA precursor absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 20S rRNA precursor measured in a cell is too low to detect." [PMID:29641590, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "20S rRNA precursor absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "20S rRNA precursor absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "20S rRNA precursor transcripts absent from cell during vegetative growth" EXACT [PomBase:vw] synonym: "undetectable 20S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth is_a: FYPO:0005996 ! altered rRNA or precursor level created_by: midori creation_date: 2019-08-19T15:15:11Z [Term] id: FYPO:0007066 name: normal 90S preribosome assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of the 90S preribosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal 90S preribosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal 90S preribosome assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-08-19T15:25:45Z [Term] id: FYPO:0007067 name: decreased protein level during stress response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular stress response to zinc ions is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during stress response to zinc ion" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to excess zinc" EXACT [Pombase:vw] synonym: "decreased protein level during cellular response to high zinc level" EXACT [PomBase:vw] synonym: "decreased protein level during cellular response to replete zinc" RELATED [PomBase:vw] synonym: "decreased protein level during cellular stress response to zinc ion" EXACT [PomBase:mah] synonym: "decreased protein level during response to zinc ion stress" EXACT [GO:1990359] synonym: "decreased protein level during response to zinc toxicity" RELATED [GO:1990359] synonym: "decreased protein level during stress response to zinc" EXACT [PomBase:mah] synonym: "decreased protein level during stress response to zinc ion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during stress response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during stress response to zinc ion" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0007051 ! altered protein level during stress response to zinc ion created_by: midori creation_date: 2019-08-19T15:31:39Z [Term] id: FYPO:0007068 name: increased origin firing efficiency in subtelomeric heterochromatin def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin located in heterochromatin at subtelomeric regions is higher than in wild type. In cells with increased origin firing efficiency, genomic DNA replication initiates from more origins than wild type, and is completed in more, smaller segments, than wild type." [PMID:18093330, PomBase:mah] synonym: "increased origin firing efficiency at subtelomeric heterochromatin" EXACT [PomBase:mah] synonym: "increased origin firing efficiency in subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased origin firing efficiency in subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased origin firing efficiency in telomeric heterochromatin" RELATED [PomBase:mah, PomBase:vw] is_a: FYPO:0001249 ! increased origin firing efficiency created_by: midori creation_date: 2019-08-19T15:33:34Z [Term] id: FYPO:0007069 name: abnormal cytosolic ribosome small subunit assembly def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which assembly of the cytosolic ribosomal small subunit is abnormal." [PomBase:mah] synonym: "abnormal 40S preribosome assembly" NARROW [PomBase:mah] synonym: "abnormal 40S ribosomal subunit assembly" NARROW [GO:0000028] synonym: "abnormal pre-40S ribosome assembly" NARROW [PMID:29641590] synonym: "abnormal ribosomal small subunit assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal ribosomal small subunit assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005017 ! abnormal ribosome biogenesis created_by: midori creation_date: 2019-08-27T15:23:17Z [Term] id: FYPO:0007070 name: abolished NLS binding def: "A molecular function phenotype in which binding to a nuclear localization sequence (NLS) in a protein by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished nuclear localisation sequence binding" EXACT [GO:0008139] synonym: "abolished nuclear localization sequence binding" EXACT [GO:0008139] synonym: "abolished nuclear localization signal binding" EXACT [GO:0008139] synonym: "NLS binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2019-08-28T16:01:54Z [Term] id: FYPO:0007071 name: increased rate of mitotic spindle elongation during anaphase A def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during anaphase a." [PMID:31427431, PomBase:mah] synonym: "increased rate of mitotic spindle elongation during anaphase A during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of mitotic spindle elongation during mitotic anaphase A" EXACT [PomBase:mah] synonym: "increased rate of mitotic spindle extension during anaphase A" EXACT [PomBase:vw] synonym: "increased rate of spindle elongation during anaphase A of mitosis" EXACT [PomBase:mah] is_a: FYPO:0007958 ! increased rate of mitotic spindle elongation created_by: midori creation_date: 2019-09-04T11:36:05Z [Term] id: FYPO:0007072 name: decreased duration of mitotic anaphase B def: "A cellular process phenotype in which the duration of progression through anaphase B of mitosis is shorter than normal. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart." [GO:0000092, PMID:31427431, PomBase:mah] synonym: "decreased duration of anaphase B during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased duration of mitotic anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of mitotic anaphase B progression" EXACT [PomBase:mah] synonym: "reduced duration of mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0000616 ! abnormal mitotic anaphase progression created_by: midori creation_date: 2019-09-04T11:38:17Z [Term] id: FYPO:0007073 name: decreased protein localization to nuclear envelope during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein localization to nuclear envelope during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004885 ! abnormal protein localization to nuclear envelope during vegetative growth created_by: midori creation_date: 2019-10-02T11:16:50Z [Term] id: FYPO:0007074 name: normal growth on mycophenolic acid def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mycophenolic acid." [PomBase:mah] synonym: "normal cell population growth in presence of mycophenolic acid" EXACT [PomBase:mah] synonym: "normal cell population growth on MPA" EXACT [PomBase:mah] synonym: "normal cell population growth on mycophenolic acid" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on mycophenolic acid" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-10-02T11:19:00Z [Term] id: FYPO:0007075 name: decreased histone H3-K14 ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 14 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3-K14 ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K14 ubiquitination during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K14 ubiquitination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002921 ! abnormal histone ubiquitination during vegetative growth created_by: midori creation_date: 2019-10-02T11:29:52Z [Term] id: FYPO:0007076 name: altered histone H3-K9 methyltransferase substrate specificity def: "A molecular function phenotype in which the substrate specificity of a gene product that executes histone H3-K9 specific methyltransferase activity is altered. For example, preference for modified (e.g. ubiquitinated) H3 molecules may be enhanced or diminished." [PMID:31468675, PomBase:mah] synonym: "altered histone methyltransferase activity (H3-K9 specific) substrate specificity" EXACT [GO:0046974] is_a: FYPO:0003347 ! altered substrate specificity is_a: FYPO:0006453 ! abnormal histone acetyltransferase activity created_by: midori creation_date: 2019-10-02T11:43:38Z [Term] id: FYPO:0007077 name: abolished ubiquitin binding def: "A molecular function phenotype in which binding to ubiquitin by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "ubiquitin binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2019-10-02T11:47:52Z [Term] id: FYPO:0007078 name: normal meiotic cell cycle process def: "A cellular process phenotype in which a cell executes a meiotic cell cycle process normally (i.e. indistinguishably from wild type). A meiotic cell cycle process is any of the processes that form part of the meiotic cell cycle, and thereby ensures successive accurate and complete genome replication and meiotic chromosome segregation." [GO:0022402, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0006915 ! normal cell cycle process created_by: midori creation_date: 2019-10-07T15:14:07Z [Term] id: FYPO:0007079 name: normal initial meiotic spindle pole body separation in meiosis II def: "A cellular process phenotype in which the initial release of duplicated spindle pole bodies that occurs as part of the second meiotic nuclear division, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. synonym: "normal initial meiotic spindle pole body separation in second meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal initial mitotic SPB separation in meiosis II" EXACT [PomBase:mah] synonym: "normal initial spindle pole body separation at meiosis II" EXACT [PomBase:vw] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2019-10-07T15:15:49Z [Term] id: FYPO:0007080 name: abnormal initial meiotic spindle pole body separation in meiosis I def: "A cellular process phenotype in which the initial release of duplicated spindle pole bodies that begins with the nucleation of microtubules from each SPB within the nucleus, and occurs as part of the first meiotic nuclear division, is abnormal." [PMID:31532702, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. synonym: "abnormal initial meiotic spindle pole body separation in first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal initial mitotic SPB separation in meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003603 ! abnormal meiosis I created_by: midori creation_date: 2019-10-07T15:21:00Z [Term] id: FYPO:0007081 name: abolished initial meiotic spindle pole body separation in meiosis I def: "A cellular process phenotype in which the initial release of duplicated spindle pole bodies that begins with the nucleation of microtubules from each SPB within the nucleus, and normally occurs as part of the first meiotic nuclear division, does not occur." [PMID:31532702, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. synonym: "abolished initial meiotic spindle pole body separation in first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abolished initial mitotic SPB separation in meiosis I" EXACT [PomBase:mah] synonym: "abolished meiotic spindle pole body separation during meiosis I" EXACT [PomBase:vw] synonym: "initial meiotic spindle pole body separation in meiosis I abolished" EXACT [PomBase:mah] is_a: FYPO:0007080 ! abnormal initial meiotic spindle pole body separation in meiosis I created_by: midori creation_date: 2019-10-07T15:21:19Z [Term] id: FYPO:0007082 name: normal spindle elongation in meiosis II def: "A cellular process phenotype in which the lengthening of the distance between poles of the meiotic spindle that occurs as part of the second meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. synonym: "normal meiotic spindle elongation in meiosis II" EXACT [PomBase:vw] synonym: "normal meiotic spindle elongation in second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2019-10-07T15:27:19Z [Term] id: FYPO:0007083 name: meiotic spindle collapse def: "A cell phenotype in which a short meiotic spindle assembles, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink." [PMID:31532702, PomBase:mah] synonym: "broken meiotic spindle" RELATED [PomBase:vw] synonym: "meiotic spindle breakage" EXACT [PomBase:mah] synonym: "spindle collapse during meiosis" EXACT [PomBase:mah] synonym: "spindle collapse during meiotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0003603 ! abnormal meiosis I created_by: midori creation_date: 2019-10-07T15:30:44Z [Term] id: FYPO:0007084 name: decreased RNA level during cellular response to sulfur starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to sulfur starvation is lower than normal. Total RNA or a specific RNA may be affected." [PMID:28388826, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to sulfur starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to sulfur starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to sulfur depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to sulfur deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to sulfur starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to sulfur starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during cellular response to sulphur starvation" EXACT [PomBase:mah] synonym: "decreased RNA level during sulfur starvation" EXACT [Pombase:al] synonym: "decreased transcript level during cellular response to sulfur starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to sulfur starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2019-10-07T15:48:04Z [Term] id: FYPO:0007085 name: increased RNA level during cellular response to sulfur starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to sulfur starvation is higher than normal. Total RNA or a specific RNA may be affected." [PMID:28388826, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to sulfur starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to sulfur starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to sulfur depletion" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to sulfur deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to sulfur starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to sulfur starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to sulphur starvation" EXACT [PomBase:mah] synonym: "increased RNA level during sulfur starvation" EXACT [PomBase:al] synonym: "increased transcript level during cellular response to sulfur starvation" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2019-10-07T15:49:41Z [Term] id: FYPO:0007086 name: elongated vegetative cell during sulfur starvation def: "A cell morphology phenotype in which a vegetative cell is elongated when the cell is subject to sulfur starvation." [PMID:28388826, PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated cell during sulfur starvation during vegetative growth" EXACT [PomBase:mah] synonym: "elongated vegetative cell during cellular response to sulfur starvation" EXACT [PomBase:mah] synonym: "elongated vegetative cell during sulfur starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "elongated vegetative cell during sulphur starvation" EXACT [PomBase:mah] is_a: FYPO:0001492 ! viable elongated vegetative cell created_by: midori creation_date: 2019-10-07T15:54:57Z [Term] id: FYPO:0007087 name: abolished sporulation during sulfur starvation def: "A cellular process phenotype in which ascospore formation does not occur when cells are subject to sulfur starvation." [PMID:28388826, PomBase:mah] synonym: "abolished sporulation during cellular response to sulfur starvation" EXACT [PomBase:mah] synonym: "absent sporulation during sulfur starvation" EXACT [PomBase:mah] synonym: "ascospore formation abolished during sulfur starvation" EXACT [PomBase:mah] synonym: "sporulation abolished during sulfur starvation" EXACT [PomBase:mah] is_a: FYPO:0000583 ! abolished sporulation created_by: midori creation_date: 2019-10-07T15:56:58Z [Term] id: FYPO:0007088 name: loss of viability upon sulfur starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to sulfur starvation." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under glucose-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "decreased viability upon sulfur starvation" EXACT [PomBase:mah] synonym: "loss of cell population viability upon sulfur starvation" EXACT [PomBase:mah] synonym: "loss of viability upon sulfur depletion" EXACT [PomBase:al] synonym: "loss of viability upon sulfur deprivation" EXACT [PomBase:mah] synonym: "loss of viability upon sulfur limitation" EXACT [PomBase:mah] synonym: "loss of viability upon sulphur starvation" EXACT [PomBase:mah] synonym: "reduced viability upon sulfur starvation" EXACT [PomBase:mah] is_a: FYPO:0000244 ! loss of viability upon nutrient depletion created_by: midori creation_date: 2019-10-07T16:00:43Z [Term] id: FYPO:0007089 name: normal cell cycle arrest at mitotic G2/M phase transition during sulfur starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally at the mitotic G2/M phase transition when the cell is subject to sulfur starvation." [PomBase:al, PomBase:mah] synonym: "normal cell cycle arrest at mitotic G2/M phase transition during sulfur depletion" EXACT [PomBase:vw] synonym: "normal cell cycle arrest at mitotic G2/M phase transition during sulfur deprivation" EXACT [PomBase:vw] synonym: "normal cell cycle arrest at mitotic G2/M phase transition during sulfur limitation" EXACT [PomBase:mah] synonym: "normal cell cycle arrest in mitotic G2 phase during sulfur starvation" RELATED [PomBase:mah] synonym: "normal mitotic cell cycle arrest at mitotic G2/M phase transition during sulfur starvation" EXACT [PomBase:mah] is_a: FYPO:0001025 ! normally arrested mitotic cell cycle progression is_a: FYPO:0001151 ! cell cycle arrest at mitotic G2/M phase transition during starvation created_by: midori creation_date: 2019-10-07T16:01:59Z [Term] id: FYPO:0007090 name: abnormal regulation of transcription by nutrient def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription as a consequence of the presence of one or more specific nutrient(s) is abnormal. For example, specific genes that are normally not transcribed in the presence of the nutrient may be transcribed in the mutant, or vice versa." [PomBase:mah] synonym: "abnormal regulation of transcription by nutrient during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of transcription by nutrient during vegetative growth" EXACT [PomBase:mah] synonym: "nutrient-insensitive transcription" RELATED [PomBase:vw] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0004527 ! abnormal regulation of transcription during vegetative growth created_by: midori creation_date: 2019-10-11T11:26:53Z [Term] id: FYPO:0007091 name: increased negative regulation of transcription by zinc def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by zinc occurs to a greater extent than normal. Specific genes that are normally not transcribed in the presence of zinc ions are not derepressed in the mutant under conditions that derepress transcription in wild type cells." [PMID:31515876, PomBase:mah] synonym: "increased gene repression in response to zinc" EXACT [PomBase:vw] synonym: "increased negative regulation of transcription by zinc during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased negative regulation of transcription by zinc during vegetative growth" EXACT [PomBase:mah] synonym: "increased negative regulation of transcription in response to zinc" EXACT [PomBase:mah] is_a: FYPO:0000624 ! abnormal negative regulation of transcription during vegetative growth is_a: FYPO:0007090 ! abnormal regulation of transcription by nutrient created_by: midori creation_date: 2019-10-11T11:27:14Z [Term] id: FYPO:0007092 name: increased DNA binding during cellular response to zinc ion def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is increased during a cellular response to zinc ions, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:31515876, PomBase:mah] synonym: "increased DNA binding during cellular response to zinc" EXACT [PomBase:mah] is_a: FYPO:0000657 ! increased DNA binding created_by: midori creation_date: 2019-10-11T11:33:00Z [Term] id: FYPO:0007093 name: increased level of ribosomal protein gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs transcribed from genes encoding ribosomal proteins measured in a cell is higher than normal (i.e. higher than observed in wild-type cells)." [PMID:28388826, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased level of ribosomal protein gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of ribosomal protein gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of ribosomal protein gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased ribosomal protein gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2019-10-11T11:42:15Z [Term] id: FYPO:0007094 name: increased duration of cell fusion during mating def: "A cellular process phenotype in which cells fuse for a longer time than normal during mating." [PMID:31495586, PomBase:mah] synonym: "increased duration of cell fusion during conjugation" EXACT [PomBase:mah] synonym: "increased duration of plasma membrane fusion involved in cytogamy" EXACT [GO:0032220, PomBase:mah] synonym: "prolonged cell fusion during mating" EXACT [PomBase:mah] is_a: FYPO:0000412 ! abnormal cell fusion during mating is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth created_by: midori creation_date: 2019-10-11T11:59:08Z [Term] id: FYPO:0007095 name: increased protein localization to actin fusion focus def: "A cell phenotype in which the localization of a protein to the actin fusion focus is increased." [PMID:31495586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to actin fusion focus" EXACT [PomBase:mah] is_a: FYPO:0004802 ! abnormal protein localization to shmoo tip is_a: FYPO:0006503 ! abnormal protein localization to actin fusion focus created_by: midori creation_date: 2019-10-11T12:03:29Z [Term] id: FYPO:0007096 name: decreased protein localization to actin fusion focus def: "A cell phenotype in which the localization of a protein to the actin fusion focus is decreased." [PMID:31495586, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to actin fusion focus" EXACT [PomBase:mah] synonym: "reduced protein localization to actin fusion focus" EXACT [PomBase:mah] is_a: FYPO:0004802 ! abnormal protein localization to shmoo tip is_a: FYPO:0006503 ! abnormal protein localization to actin fusion focus created_by: midori creation_date: 2019-10-11T12:05:08Z [Term] id: FYPO:0007097 name: ectopic actin fusion focus assembly def: "A cellular process phenotype in which actin fusion focus assembly takes place in one or more abnormal locations. An actin fusion focus normally forms during mating at the site where the two cells will fuse. Ectopic fusion foci often form near actin cortical patches, and may also have abnormal composition." [PMID:31495586, PomBase:mah] synonym: "ectopic actin fusion focus formation" EXACT [PomBase:mah] synonym: "mislocalized actin fusion focus assembly" EXACT [PomBase:mah] is_a: FYPO:0006108 ! abnormal actin fusion focus assembly created_by: midori creation_date: 2019-10-11T12:12:09Z [Term] id: FYPO:0007098 name: normal growth on vanadate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing vanadate ions (VO4(3-))." [PomBase:mah] synonym: "normal cell population growth in presence of vanadate" EXACT [PomBase:mah] synonym: "normal cell population growth on vanadate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on vanadate ions" EXACT [PomBase:mah] synonym: "normal growth on orthovanadate" EXACT [CHEBI:46442] synonym: "normal growth on vanadate(3-)" EXACT [CHEBI:46442] synonym: "normal growth on vanadium oxoanion" BROAD [CHEBI:30528] synonym: "normal vegetative cell population growth on vanadate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-10-11T13:43:34Z [Term] id: FYPO:0007099 name: normal spindle elongation in meiosis I def: "A cellular process phenotype in which the lengthening of the distance between poles of the meiotic spindle that occurs as part of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. synonym: "normal meiotic spindle elongation in first meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal meiotic spindle elongation in meiosis I" EXACT [PomBase:vw] is_a: FYPO:0002739 ! abnormal meiotic cell cycle process is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2019-10-11T13:55:16Z [Term] id: FYPO:0007100 name: abnormal cell cycle arrest in meiotic prophase I with clustered telomeres def: "A cellular process phenotype in which the first meiotic nuclear division is arrested in prophase I under conditions where arrest does not normally occur, and with telomeres clustered at the spindle pole body. Telomere clustering at the SPB indicates that the cell has reached or passed the pachytene stage." [PMID:21449049, PomBase:mah] synonym: "abnormal cell cycle arrest in meiotic prophase I at or after pachytene" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in meiotic prophase I with telomeres clustered at SPB" EXACT [PomBase:al] synonym: "abnormal cell cycle arrest in meiotic prophase I with telomeres clustered at spindle pole bodies" EXACT [PomBase:al] is_a: FYPO:0002817 ! abnormally arrested meiosis I created_by: midori creation_date: 2019-10-11T14:08:51Z [Term] id: FYPO:0007101 name: bent spindle during meiosis I def: "A spindle phenotype in which the meiotic spindle is not straight, but instead forms an angle where microtubules from opposite poles interdigitate, during meiosis I." [PMID:22292001, PomBase:mah] synonym: "bent bipolar spindle during meiosis I" EXACT [PomBase:vw] synonym: "bent meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "bent spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "V-shaped bipolar spindle during meiosis I" EXACT [PomBase:vw] is_a: FYPO:0000734 ! abnormal meiotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology created_by: midori creation_date: 2019-10-16T14:41:07Z [Term] id: FYPO:0007102 name: multiple spindles during meiosis II def: "A physical cellular phenotype in which a cell contains more than one meiotic spindle per nucleus during the second meiotic nuclear division." [PMID:22292001, PomBase:mah] synonym: "additional spindles present during meiosis II" EXACT [PomBase:mah] synonym: "extra spindles during meiosis II" EXACT [PomBase:mah] synonym: "increased number of spindles during meiosis II" EXACT [PomBase:vw] synonym: "multiple meiotic spindles during meiosis II" EXACT [PomBase:mah] synonym: "spindles present in greater numbers during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0006390 ! multiple meiotic spindles created_by: midori creation_date: 2019-10-16T14:43:31Z [Term] id: FYPO:0007103 name: spindle collapse during meiosis I def: "A cell phenotype in which a short meiotic spindle assembles during meiosis I, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink." [PMID:22292001, PomBase:mah] comment: Sister chromatids may separate in meiosis I due to problems with either cohesion or kinetochore attachment to microtubules. Therefore consider also annotating to 'abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation' (FYPO:0000209), 'decreased meiotic sister chromatid cohesion' (FYPO:0002093), or 'merotelic kinetochore attachment during meiosis I' (FYPO:0005638). synonym: "broken spindle during meiosis I" RELATED [PomBase:mah] synonym: "meiotic spindle collapse during meiosis I" EXACT [PomBase:mah] synonym: "spindle breakage during meiosis I" RELATED [PomBase:mah] synonym: "spindle collapse during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007083 ! meiotic spindle collapse created_by: midori creation_date: 2019-10-16T14:50:27Z [Term] id: FYPO:0007104 name: abnormal homologous chromosome arm segregation def: "A cellular process phenotype in which homologous chromosome segregation is abnormal along the chromosome arms." [PMID:22292001, PomBase:mah] synonym: "abnormal homologous chromosome arm segregation during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome arm segregation during meiosis I" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome arm separation" RELATED [PomBase:mah] is_a: FYPO:0004159 ! abnormal homologous chromosome segregation created_by: midori creation_date: 2019-10-16T15:06:11Z [Term] id: FYPO:0007105 name: increased duration of Rad52 focus presence during meiotic cell cycle def: "A cell phenotype in which sites at which the protein Rad52 accumulates remain present for a longer time than normal during the meiotic cell cycle. Normally, Rad52 foci form during prophase I but disappear before metaphase I." [PMID:22292001, PomBase:mah] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2019-10-16T15:13:59Z [Term] id: FYPO:0007106 name: normal mitotic spindle morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the mitotic spindle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "normal mitotic spindle morphology during vegetative growth" EXACT [PomBase:mah] synonym: "normal spindle morphology during mitosis" EXACT [PomBase:mah] synonym: "normal spindle morphology during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2019-10-16T15:17:00Z [Term] id: FYPO:0007107 name: normal microtubule cytoskeleton organization during meiosis I def: "A cellular process phenotype in which microtubule cytoskeleton organization is normal (i.e. indistinguishable from wild type) during meiosis I. Microtubule cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] synonym: "normal microtubule cytoskeleton organisation during meiosis I" EXACT [PomBase:mah] synonym: "normal microtubule cytoskeleton organization during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "normal microtubule dynamics during meiosis I" EXACT [GO:0000226, PomBase:mah] synonym: "normal microtubule organization during meiosis I" RELATED [GO:0000226, PomBase:mah] is_a: FYPO:0007277 ! normal cellular process during meiotic cell cycle created_by: midori creation_date: 2019-10-16T15:44:20Z [Term] id: FYPO:0007108 name: abnormal meiotic centromere clustering during meiotic prophase I def: "A cellular process phenotype in which centromere clustering takes place during meiotic prophase I, and remains incomplete. Normally, centromeres and SPBs associate during prometaphase I, but not earlier." [PMID:15298676, PomBase:mah] synonym: "abnormal centromere clustering during meiotic prophase I" EXACT [GO:1990571] synonym: "abnormal chromosome retrieval during meiotic prophase I" RELATED [PomBase:vw] synonym: "abnormal kinetochore retrieval during meiotic prophase I" RELATED [Pombase:vw] synonym: "abnormal meiotic centromere clustering during prophase I" EXACT [PomBase:mah] synonym: "increased unclustered centromeres during meiotic prophase I" RELATED [PomBase:vw] synonym: "premature meiotic centromere clustering during meiotic prophase I" RELATED [PomBase:mah] is_a: FYPO:0004086 ! abnormal meiotic centromere clustering created_by: midori creation_date: 2019-10-16T15:54:47Z [Term] id: FYPO:0007109 name: normal meiotic centromere clustering during meiotic prometaphase I def: "A cellular process phenotype in which centromere clustering is normal (i.e. indistinguishable from wild type during meiotic prometaphase I." [PomBase:mah] synonym: "normal centromere clustering during meiotic prometaphase I" EXACT [GO:1990571] synonym: "normal chromosome retrieval during meiotic prometaphase I" RELATED [PomBase:vw] synonym: "normal kinetochore retrieval during meiotic prometaphase I" RELATED [Pombase:vw] synonym: "normal meiotic centromere clustering during prometaphase I" EXACT [PomBase:mah] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: midori creation_date: 2019-10-16T16:04:39Z [Term] id: FYPO:0007110 name: microtubule bundles present in decreased numbers at spindle pole body during meiosis I def: "A physical cellular phenotype in which cells contain fewer microtubule bundles associated with the spindle pole body than normal during meiosis I." [PomBase:mah] synonym: "decreased level of MT bundles at spindle pole body during meiosis I" EXACT [PomBase:al] synonym: "decreased number of microtubule bundles at spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "meiosis I SPB microtubule bundles present in decreased numbers" EXACT [PomBase:vw] synonym: "microtubule bundles present in decreased numbers at SPB during meiosis I" EXACT [PomBase:mah] synonym: "microtubule bundles present in lower numbers at spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "microtubule bundles present in reduced numbers at spindle pole body during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0002818 ! microtubule bundles present in decreased numbers created_by: midori creation_date: 2019-10-16T16:06:05Z [Term] id: FYPO:0007111 name: abnormal microtubule depolymerization def: "A cellular process phenotype in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal." [GO:0007019, PomBase:mah] synonym: "abnormal microtubule catastrophe" RELATED [PomBase:mah] synonym: "abnormal microtubule depolymerisation" EXACT [PomBase:mah] synonym: "abnormal microtubule shrinkage" RELATED [PomBase:vw] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization created_by: midori creation_date: 2019-10-30T11:45:25Z [Term] id: FYPO:0007112 name: decreased rate of microtubule depolymerization involved in meiotic centromere clustering during meiotic prophase I def: "A cellular process in which depolymerization (i.e. removal of tubulin dimers) of microtubules occurs at a lower rate, or speed, as part of centromere clustering during meiotic prophase I." [PMID:23770679, PomBase:mah] synonym: "decreased microtubule depolymerisation speed involved in meiotic centromere clustering during meiotic prophase I" EXACT [] synonym: "decreased microtubule depolymerization speed involved in meiotic centromere clustering during meiotic prophase I" EXACT [] synonym: "decreased microtubule shrinkage shrinkage speed involved in meiotic centromere clustering during meiotic prophase I" EXACT [PomBase:vw] synonym: "decreased microtubule shrinkage speed involved in meiotic centromere clustering during meiotic prophase I" EXACT [] synonym: "decreased rate of microtubule depolymerisation involved in meiotic centromere clustering during meiotic prophase I" EXACT [PomBase:mah] synonym: "decreased rate of microtubule depolymerization involved in meiotic centromere clustering during prophase I" EXACT [PomBase:mah] synonym: "decreased rate of microtubule depolymerization involved in meiotic chromosome clustering during meiotic prophase I" RELATED [PomBase:vw] synonym: "decreased rate of microtubule depolymerization involved in meiotic kinetochore retrieval during meiotic prophase I" RELATED [PomBase:vw] synonym: "reduced rate of microtubule depolymerization involved in meiotic centromere clustering during meiotic prophase I" EXACT [PomBase:mah] is_a: FYPO:0007111 ! abnormal microtubule depolymerization is_a: FYPO:0009058 ! decreased microtubule depolymerisation involved in meitotic centromere clustering during meiotic prophase I created_by: midori creation_date: 2019-10-30T11:45:53Z [Term] id: FYPO:0007113 name: abnormal microtubule cytoskeleton organization during meiotic cell cycle def: "A phenotype that affects the organization of the microtubule cytoskeleton during all or part of the meiotic cell cycle. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] comment: Consider annotating to 'abnormal microtubule cytoskeleton' (FYPO:0002399), but note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in a physically abnormal microtubule cytoskeleton. synonym: "abnormal microtubule cytoskeleton organisation during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal microtubule organisation during meiotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal microtubule organization during meiotic cell cycle" RELATED [PomBase:mah] synonym: "disorganized microtubule cytoskeleton during meiotic cell cycle" RELATED [PomBase:vw] synonym: "microtubule cytoskeleton defects during meiotic cell cycle" EXACT [PomBase:mah] synonym: "microtubule organization defects during meiotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization created_by: midori creation_date: 2019-10-30T11:46:27Z [Term] id: FYPO:0007114 name: normal microtubule bundle def: "A physical cellular phenotype in which the amount, distribution, and morphology of microtubule bundles are normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal microtubule array" RELATED [PomBase:vw] synonym: "normal microtubule bundle physical object quality" EXACT [PomBase:mah] synonym: "normal MT bundle" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2019-10-30T13:58:21Z [Term] id: FYPO:0007115 name: abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished, and the protein is present in the cytoplasm instead, during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortical node, with protein mislocalised to cytoplasm during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cortical medial dot, with protein mislocalized to cytoplasm during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cytokinetic nodes, with protein mislocalized to cytoplasm during mitotic interphase" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm, during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm, during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortical nodes, with protein mislocalized to cytoplasm during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein recruitment to medial cortical node, with protein mislocalized to cytoplasm during mitotic interphase" RELATED [PomBase:vw] synonym: "protein localization to medial cortical node abolished, with protein mislocalized to cytoplasm during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0004735 ! abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm is_a: FYPO:0007139 ! abolished protein localization to medial cortical node during mitotic interphase created_by: midori creation_date: 2019-10-30T14:00:13Z [Term] id: FYPO:0007116 name: decreased protein level in actomyosin contractile ring during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein in the actomyosin contractile ring is lower than normal during interphase of the mitotic cell cycle." [PMID:23615450, PomBase:mah] comment: Use this term for cases where the relative abundance of one or more specific proteins in the proteasome is decreased, altering the proteasome stoichiometry. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level in actomyosin contractile ring during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in actomyosin contractile ring during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased protein level in contractile ring during mitotic interphase" EXACT [PomBase:vw] synonym: "reduced protein level in actomyosin contractile ring during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0004736 ! abnormal actomyosin contractile ring created_by: midori creation_date: 2019-10-30T14:07:25Z [Term] id: FYPO:0007117 name: decreased RNA level during cellular response to leucine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to leucine starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased mRNA level during cellular response to leucine starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to leucine starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to leucine depletion" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to leucine deprivation" EXACT [PomBase:vw] synonym: "decreased RNA level during cellular response to leucine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to leucine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA level during leucine starvation" EXACT [PomBase:al] synonym: "decreased transcript level during cellular response to leucine starvation" EXACT [PomBase:vw] synonym: "reduced RNA level during cellular response to leucine starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2019-10-30T14:13:15Z [Term] id: FYPO:0007118 name: increased RNA level during cellular response to leucine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to leucine starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased mRNA level during cellular response to leucine starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to leucine starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to leucine depletion" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to leucine deprivation" EXACT [PomBase:vw] synonym: "increased RNA level during cellular response to leucine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to leucine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during leucine starvation" EXACT [PomBase:al] synonym: "increased transcript level during cellular response to leucine starvation" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2019-10-30T14:14:32Z [Term] id: FYPO:0007119 name: loss of viability upon amino acid starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to starvation for one or more amino acids." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under glucose-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "decreased viability upon amino acid starvation" EXACT [PomBase:mah] synonym: "loss of cell population viability upon amino acid starvation" EXACT [PomBase:mah] synonym: "loss of viability upon amino acid depletion" EXACT [PomBase:al] synonym: "loss of viability upon amino acid deprivation" EXACT [PomBase:mah] synonym: "loss of viability upon amino acid limitation" EXACT [PomBase:mah] synonym: "reduced viability upon amino acid starvation" EXACT [PomBase:mah] is_a: FYPO:0000244 ! loss of viability upon nutrient depletion created_by: midori creation_date: 2019-10-30T14:15:40Z [Term] id: FYPO:0007120 name: abolished cell cycle arrest in mitotic G1 phase in response to leucine starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to leucine starvation does not occur; arrest normally occurs in G1 phase." [PMID:31456006, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abolished cell cycle arrest in mitotic G1 phase during cellular response to leucine starvation" EXACT [PomBase:mah] synonym: "abolished cell cycle arrest in mitotic G1 phase in response to leucine depletion" EXACT [PomBase:vw] synonym: "abolished cell cycle arrest in mitotic G1 phase in response to leucine deprivation" EXACT [PomBase:vw] synonym: "abolished leucine deprivation-induced G1 arrest" EXACT [PomBase:vw] synonym: "abolished mitotic cell cycle arrest in G1 phase in response to leucine starvation" EXACT [PomBase:mah] synonym: "abolished mitotic G1 arrest in response to leucine starvation" EXACT [PomBase:mah] synonym: "cell cycle arrest in mitotic G1 phase in response to leucine starvation abolished" EXACT [PomBase:mah] is_a: FYPO:0001026 ! abnormal occurrence of normal mitotic cell cycle arrest created_by: midori creation_date: 2019-10-30T14:18:15Z [Term] id: FYPO:0007121 name: normal growth on iron def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing iron ions." [PomBase:mah] synonym: "normal cell population growth in presence of iron" EXACT [PomBase:mah] synonym: "normal cell population growth on iron" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on iron ion" EXACT [PomBase:mah] synonym: "normal cellular response to iron" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on iron ions" EXACT [PomBase:mah] synonym: "normal vegetative cell population growth on iron" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-10-30T14:25:37Z [Term] id: FYPO:0007122 name: decreased mitochondrial respiratory chain complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of assembly of one or more mitochondrial respiratory chain complexes is decreased." [PMID:31350787, PomBase:mah] synonym: "decreased mitochondrial respiratory chain complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial respiratory chain complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitochondrial respiratory complex assembly" EXACT [PomBase:vw] synonym: "reduced mitochondrial respiratory chain complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: midori creation_date: 2019-10-30T14:26:49Z [Term] id: FYPO:0007123 name: unbundled spindle during mitotic prophase def: "A physical cellular phenotype observed during mitotic prophase (in the vegetative growth phase of the life cycle) in which the mitotic spindle has two poles, but spindle microtubules (MTs) are not aligned into parallel or anti-parallel bundles. Instead, MTs extend in random directions from the asters, and the spindle does not elongate." [PMID:31615768, PomBase:mah] comment: In images of thin spindles, polar microtubules may appear not to reach continuously from pole to pole. synonym: "unbundled spindle during mitotic prophase during prophase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "unbundled spindle during mitotic prophase during vegetative growth" EXACT [PomBase:mah] synonym: "unbundled spindle microtubules during mitotic prophase" EXACT [PomBase:mah] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle created_by: midori creation_date: 2019-10-30T14:45:17Z [Term] id: FYPO:0007124 name: normal protein localization to mitotic spindle midzone during prophase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during prophase is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GO:1990023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle midzone during prophase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle midzone during prophase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to spindle midzone during prophase during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0004692 ! normal protein localization to mitotic spindle midzone created_by: midori creation_date: 2019-10-30T14:49:48Z [Term] id: FYPO:0007125 name: mitotic sister chromatid separation in absence of mitotic spindle def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation begins when the mitotic spindle is not present." [PMID:9864354, PomBase:mah] synonym: "mitotic chromosome separation in absence of mitotic spindle" EXACT [PomBase:mah] synonym: "mitotic sister chromatid separation in absence of mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic sister chromatid separation without mitotic spindle" EXACT [PomBase:mah] synonym: "sister chromatid separation in absence of spindle during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2019-11-04T12:09:34Z [Term] id: FYPO:0007126 name: abnormal microtubule bundle formation during mitotic spindle assembly def: "A cellular process phenotype in which microtubule bundle formation that takes place as part of mitotic spindle assembly, and which normally results in a parallel arrangement of microtubules, is abnormal." [GO:0001578, PMID:31615768, PomBase:mah] synonym: "abnormal microtubule array formation during mitotic spindle assembly" RELATED [PomBase:vw] synonym: "abnormal microtubule bundle formation in spindle during mitotic prophase" RELATED [PomBase:vw] synonym: "abnormal microtubule bundle formation involved in mitotic spindle assembly" EXACT [PomBase:mah] synonym: "abnormal mitotic spindle microtubule bundling during prophase" EXACT [PomBase:vw] synonym: "abnormal mitotic spindle microtubule bundling during spindle assembly" RELATED [PomBase:vw] is_a: FYPO:0002761 ! abnormal microtubule bundle formation created_by: midori creation_date: 2019-11-04T13:39:51Z [Term] id: FYPO:0007127 name: abnormal actomyosin contractile ring maturation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring maturation is abnormal." [GO:1902406, PomBase:mah] synonym: "abnormal actomyosin contractile ring maintenance" EXACT [GO:1902406] synonym: "abnormal actomyosin contractile ring maturation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal actomyosin contractile ring maturation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring maturation" EXACT [PomBase:mah] synonym: "abnormal mitotic actomyosin contractile ring maintenance" EXACT [GO:1902406] synonym: "abnormal mitotic actomyosin contractile ring maturation" EXACT [GO:1902406] synonym: "abnormal mitotic contractile ring maintenance" EXACT [PomBase:vw] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization during vegetative growth created_by: midori creation_date: 2019-11-04T13:57:19Z [Term] id: FYPO:0007128 name: abnormal mitotic chromosome movement towards spindle pole def: "A cellular process phenotype in which movement of chromosomes from the center of the mitotic spindle towards the spindle poles is abnormal. This normally takes place during mitotic anaphase A." [GO:0007079, PMID:11870212, PomBase:mah] synonym: "abnormal chromosome movement during mitotic anaphase A" EXACT [PomBase:vw] synonym: "abnormal chromosome movement towards spindle pole during mitosis" EXACT [PomBase:mah] synonym: "abnormal mitotic chromosome movement towards spindle pole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic chromosome movement towards spindle pole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic sister chromatid separation created_by: midori creation_date: 2019-11-04T14:00:44Z [Term] id: FYPO:0007129 name: abnormal homoserine O-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of homoserine O-acetyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2019-11-04T14:08:18Z [Term] id: FYPO:0007130 name: abolished homoserine O-acetyltransferase activity def: "A molecular function phenotype in which homoserine O-acetyltransferase activity is absent." [PomBase:mah] synonym: "homoserine O-acetyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0007129 ! abnormal homoserine O-acetyltransferase activity created_by: midori creation_date: 2019-11-04T14:08:25Z [Term] id: FYPO:0007131 name: increased protein localization to microtubule plus-end def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends end of microtubules is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to microtubule plus-end" EXACT [PomBase:mah] synonym: "increased protein localization to microtubule plus end" EXACT [PomBase:mah] synonym: "increased protein localization to microtubule plus-end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to microtubule plus-end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000932 ! increased protein localization to microtubule cytoskeleton during vegetative growth created_by: midori creation_date: 2019-11-04T14:11:57Z [Term] id: FYPO:0007132 name: increased microtubule binding def: "A molecular function phenotype in which the binding of a protein to one or more microtubules occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with actin filaments that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0001943 ! abnormal microtubule binding created_by: midori creation_date: 2019-11-04T14:14:29Z [Term] id: FYPO:0007133 name: normal protein localization to medial cortical node during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to medial cortical node during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein localization to cortical medial dot during mitotic interphase" EXACT [PomBase:vw] synonym: "normal protein localization to cytokinetic nodes during mitotic interphase" EXACT [PMID:24127216] synonym: "normal protein localization to medial cortical node during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to medial cortical node during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to medial cortical nodes during mitotic interphase" EXACT [PomBase:mah] synonym: "normal protein recruitment to medial cortical node during mitotic interphase" RELATED [PomBase:vw] is_a: FYPO:0002999 ! normal protein localization to medial cortical node created_by: midori creation_date: 2019-11-04T14:34:36Z [Term] id: FYPO:0007134 name: normal septation initiation network signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling is normal (i.e. indistinguishable from wild type). SIN signaling is mediated by the small GTPase Ras, and results in the initiation of contraction of the contractile ring at the beginning of cytokinesis and cell division by septum formation." [GO:0031028, PomBase:mah] synonym: "normal septation initiation network signaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal septation initiation network signaling during vegetative growth" EXACT [PomBase:mah] synonym: "normal septation initiation network signalling" EXACT [PomBase:mah] synonym: "normal septation initiation signaling" EXACT [GO:0031028] synonym: "normal SIN signaling" EXACT [PomBase:mah] synonym: "normal SIN signalling" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-11-04T14:38:22Z [Term] id: FYPO:0007135 name: increased level of AP sites in DNA def: "A phenotype in which the number of apurinic and ayprimidinic (collectively, AP) sites detected in DNA is greater than normal. An AP is a deoxyribose sugar with a missing base, and is formed by the enzymatic removal of a damaged base." [PMID:12810074, PomBase:mah] synonym: "increased level of apurinic/apyrimidinic sites in DNA" EXACT [PomBase:mah] synonym: "increased level of DNA AP sites" EXACT [PomBase:al] synonym: "increased level of DNA apurinic/apyrimidinic sites" EXACT [PomBase:al] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2019-11-04T14:51:21Z [Term] id: FYPO:0007136 name: small mononucleate vegetative cell def: "A cell phenotype in which a cell contains one nucleus and has an abnormally low volume." [PomBase:mah] synonym: "small mononucleate cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small mononucleate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0000645 ! small vegetative cell relationship: has_part FYPO:0000060 ! mononucleate vegetative cell relationship: has_part FYPO:0000645 ! small vegetative cell created_by: midori creation_date: 2019-11-04T14:57:06Z [Term] id: FYPO:0007137 name: small multinucleate vegetative cell def: "A cell morphology phenotype in which a vegetative cell has an abnormally low volume and contains more than one nucleus." [PomBase:mah] synonym: "small multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "small multinucleate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000061 ! multinucleate vegetative cell is_a: FYPO:0000645 ! small vegetative cell relationship: has_part FYPO:0000061 ! multinucleate vegetative cell relationship: has_part FYPO:0000645 ! small vegetative cell created_by: midori creation_date: 2019-11-04T14:58:52Z [Term] id: FYPO:0007138 name: inviable small multiseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, has an abnormally low volume, and contains more than one septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable small multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "lethal; small multiseptate vegetative cell" EXACT [PomBase:mah] synonym: "small inviable multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "small multiseptate inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0000951 ! inviable small vegetative cell is_a: FYPO:0002452 ! inviable septated vegetative cell with abnormal cell morphology relationship: has_part FYPO:0000118 ! multiseptate vegetative cell created_by: midori creation_date: 2019-11-04T15:01:47Z [Term] id: FYPO:0007139 name: abolished protein localization to medial cortical node during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortical node during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cortical medial dot during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to cytokinetic nodes during mitotic interphase" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortical node during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortical node during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortical nodes during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein recruitment to medial cortical node during mitotic interphase" RELATED [PomBase:vw] synonym: "protein localization to medial cortical node abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0003919 ! abolished protein localization to medial cortical node created_by: midori creation_date: 2019-11-05T12:27:48Z [Term] id: FYPO:0007140 name: inviable after spore germination, multiple cell divisions, swollen, elongated cell def: "A phenotype in which a spore germinates to produce a cell that has a greater length, diameter, volume, and length:diameter ratio than normal, and undergoes two or more rounds of cell division and then dies." [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, swollen, elongated cell" EXACT [PomBase:mah] synonym: "inviable germinated spore, multiple cell divisions, swollen, elongated cell" EXACT [PomBase:mah] synonym: "lethal after spore germination, multiple cell divisions, swollen, elongated cell" EXACT [PomBase:mah] is_a: FYPO:0002251 ! inviable swollen elongated vegetative cell is_a: FYPO:0002262 ! inviable after spore germination, multiple cell divisions, elongated cell is_a: FYPO:0002415 ! inviable swollen vegetative cell with abnormal cell shape is_a: FYPO:0002490 ! inviable after spore germination, multiple cell divisions, swollen cell created_by: midori creation_date: 2019-11-11T11:31:10Z [Term] id: FYPO:0007141 name: abolished endodeoxyribonuclease activity def: "A molecular function phenotype in which an endodeoxyribonuclease activity is absent." [PomBase:mah] synonym: "endodeoxyribonuclease activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0002036 ! abnormal endodeoxyribonuclease activity created_by: midori creation_date: 2019-11-11T11:34:01Z [Term] id: FYPO:0007142 name: loss of viability following cellular response to ionizing radiation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to ionizing radiation." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown with exposure to UV light, and then the number of cells viable enough to form a colony upon return to absence of UV is measured and compared to wild type. synonym: "decreased viability following cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "loss of cell population viability following cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "loss of viability following cellular response to gamma radiation" NARROW [PomBase:mah] synonym: "loss of viability following cellular response to IR" EXACT [PomBase:mah] synonym: "loss of viability following ionizing radiation exposure" EXACT [PomBase:mah] synonym: "reduced viability following cellular response to ionizing radiation" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2019-11-11T15:29:58Z [Term] id: FYPO:0007143 name: increased 5'-deoxyribonuclease (pyrimidine dimer) activity def: "A molecular function phenotype in which the observed rate of 5'-deoxyribonuclease (pyrimidine dimer) activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0004028 ! abnormal 5' deoxyribonuclease (pyrimidine dimer) activity created_by: midori creation_date: 2019-11-11T15:40:25Z [Term] id: FYPO:0007144 name: increased deoxyribonuclease (pyrimidine dimer) activity during cellular response to UV def: "A molecular function phenotype in which the observed rate of deoxyribonuclease (pyrimidine dimer) activity is increased during a cellular response to ultraviolet light." [PomBase:mah] synonym: "increased 5'-deoxyribonuclease (pyrimidine dimer) activity during cellular response to UV" NARROW [Pombase:al] synonym: "increased deoxyribonuclease (pyrimidine dimer) activity during cellular response to ultraviolet light" EXACT [PomBase:al] is_a: FYPO:0004415 ! increased phosphatase activity is_a: FYPO:0007143 ! increased 5'-deoxyribonuclease (pyrimidine dimer) activity created_by: midori creation_date: 2019-11-11T15:40:36Z [Term] id: FYPO:0007145 name: normal 5' deoxyribonuclease (pyrimidine dimer) activity during cellular response to UV def: "A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light." [PomBase:mah] synonym: "normal 5' deoxyribonuclease (pyrimidine dimer) activity during cellular response to ultraviolet light" EXACT [PomBase:mah] is_a: FYPO:0004027 ! normal 5' deoxyribonuclease (pyrimidine dimer) activity created_by: midori creation_date: 2019-11-11T16:08:57Z [Term] id: FYPO:0007146 name: abolished protein localization to nucleus, with protein mislocalized to cytoplasm, during meiotic cell cycle def: "A cell phenotype in which the localization of a protein to the nucleus is abolished, and the protein is present in the cytoplasm instead, during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization in nucleus, with protein mislocalized to cytoplasm, during meiotic cell cycle" EXACT [GO:0034504] synonym: "nuclear exclusion, with protein mislocalized to cytoplasm, during meiotic cell cycle" RELATED [PomBase:vw] synonym: "nuclear protein exclusion, with protein mislocalized to cytoplasm, during meiotic cell cycle" RELATED [PomBase:vw] synonym: "protein localization to nucleus abolished, with protein mislocalized to cytoplasm, during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003450 ! abolished protein localization to nucleus is_a: FYPO:0004842 ! protein mislocalized to cytoplasm relationship: has_part FYPO:0004842 ! protein mislocalized to cytoplasm created_by: midori creation_date: 2019-11-11T16:15:41Z [Term] id: FYPO:0007147 name: normal Mei2 nuclear dot formation def: "A cellular process phenotype in which Mei2 nuclear dot formation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal Mei2 nuclear dot assembly" EXACT [PomBase:mah] synonym: "normal meiRNA nuclear dot formation" RELATED [PMID:24920274, PomBase:mah] is_a: FYPO:0006839 ! normal protein-containing complex assembly created_by: midori creation_date: 2019-11-11T16:32:09Z [Term] id: FYPO:0007148 name: sensitive to transplatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to transplatin. Cells stop growing (and may die) at a concentration of transplatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to transplatin" EXACT [PomBase:mah] synonym: "sensitive to transplatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to v during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-11-11T16:36:18Z [Term] id: FYPO:0007149 name: normal growth on N-methyl-N'-nitro-N-nitrosoguanidine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)." [PomBase:mah] synonym: "normal cell population growth in presence of N-methyl-N'-nitro-N-nitrosoguanidine" EXACT [PomBase:mah] synonym: "normal cell population growth on MNNG" EXACT [CHEBI:21759] synonym: "normal cell population growth on N-methyl-N'-nitro-N-nitrosoguanidine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on N-methyl-N'-nitro-N-nitrosoguanidine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-11-11T16:38:13Z [Term] id: FYPO:0007150 name: decreased microtubule bundle formation def: "A cellular process phenotype in which the occurrence of microtubule bundle formation, which normally results in a parallel arrangement of microtubules, is decreased." [PomBase:mah] synonym: "decreased microtubule array formation" RELATED [PomBase:mah] synonym: "decreased microtubule bundling" EXACT [PomBase:mah] synonym: "reduced microtubule bundle formation" EXACT [PomBase:mah] is_a: FYPO:0002761 ! abnormal microtubule bundle formation created_by: midori creation_date: 2019-11-19T13:19:07Z [Term] id: FYPO:0007151 name: long actin cables def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are longer than normal." [PomBase:mah] synonym: "elongated actin cables" EXACT [PomBase:mah] synonym: "increased actin cable length" EXACT [PomBase:mah] synonym: "long actin cables during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long actin cables during vegetative growth" EXACT [PomBase:mah] synonym: "long formin-nucleated actin cables" EXACT [PomBase:mah] is_a: FYPO:0002031 ! abnormal actin cable morphology created_by: midori creation_date: 2019-11-19T13:23:27Z [Term] id: FYPO:0007152 name: sensitive to camphor def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to camphor. Cells stop growing (and may die) at a concentration of camphor that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to camphor" EXACT [PomBase:mah] synonym: "sensitive to camphor during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to camphor during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-11-19T13:24:46Z [Term] id: FYPO:0007153 name: normal polyphosphate catabolism during cellular response to phosphate starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the breakdown of polyphosphate is normal (i.e. indistinguishable from wild type) during a cellular response to phosphate starvation." [PMID:1318242, PomBase:mah] synonym: "normal polyphosphate catabolic process during cellular response to phosphate starvation" EXACT [GO:0006798] synonym: "normal polyphosphate catabolism during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal polyphosphate catabolism during cellular response to phosphate starvation during vegetative growth" EXACT [PomBase:mah] synonym: "normal polyphosphate degradation during cellular response to phosphate starvation" EXACT [GO:0006798] is_a: FYPO:0000859 ! normal metabolic process during vegetative growth created_by: midori creation_date: 2019-11-19T14:10:09Z [Term] id: FYPO:0007154 name: normal polyphosphate biosynthesis during cellular response to replete phosphate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of polyphosphate is normal (i.e. indistinguishable from wild type) during a cellular response to replete phosphate." [PMID:1318242, PomBase:mah] synonym: "normal polyphosphate biosynthesis during cellular response to phosphate starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal polyphosphate biosynthesis during cellular response to replete phosphate during vegetative growth" EXACT [PomBase:mah] synonym: "normal polyphosphate biosynthetic process during cellular response to phosphate starvation" EXACT [GO:0006799] synonym: "normal polyphosphate formation during cellular response to replete phosphate" EXACT [GO:0006799] is_a: FYPO:0000859 ! normal metabolic process during vegetative growth created_by: midori creation_date: 2019-11-19T14:13:03Z [Term] id: FYPO:0007155 name: obsolete ectopic activation of mitotic cell cycle spindle assembly checkpoint def: "OBSOLETE. A cell cycle checkpoint phenotype in which the mitotic spindle assembly checkpoint is activated at an abnormal location. The mitotic spindle assembly checkpoint is normally activated at kinetochores, and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PomBase:mah, PomBase:vw] comment: This term was made obsolete because it is not an accurate description of an observed phenotype. synonym: "ectopic mitotic cell cycle spindle assembly checkpoint activation" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2019-11-19T14:22:57Z [Term] id: FYPO:0007156 name: increased protein localization to medial cortical node def: "A cell phenotype in which the localization of a protein to the medial cortical nodes is increased in the vegetative growth phase of the life cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "increased protein localization to cytokinetic nodes" RELATED [PomBase:mah] synonym: "increased protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein recruitment to medial cortical node" RELATED [PomBase:vw] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node created_by: midori creation_date: 2019-11-19T14:29:45Z [Term] id: FYPO:0007157 name: abnormal histone binding def: "A molecular function phenotype in which occurrence of histone binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds one or more methylated histone(s) differently from wild type, or that a mutation in one gene affects methylated histone binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000704 ! abnormal protein-protein interaction created_by: midori creation_date: 2019-11-19T14:33:27Z [Term] id: FYPO:0007158 name: decreased histone H3 binding def: "A molecular function phenotype in which occurrence of histone H3 binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:31584934, PomBase:mah] synonym: "decreased protein-histone H3 interaction" EXACT [PomBase:mah] synonym: "reduced histone H3 binding" EXACT [PomBase:mah] is_a: FYPO:0007157 ! abnormal histone binding created_by: midori creation_date: 2019-11-19T14:34:22Z [Term] id: FYPO:0007159 name: decreased histone H4 binding def: "A molecular function phenotype in which occurrence of histone H4 binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:31584934, PomBase:mah] synonym: "decreased protein-histone H4 interaction" EXACT [PomBase:mah] synonym: "reduced histone H4 binding" EXACT [PomBase:mah] is_a: FYPO:0007157 ! abnormal histone binding created_by: midori creation_date: 2019-11-19T14:38:22Z [Term] id: FYPO:0007160 name: abnormal DNA replication-dependent nucleosome assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of nucleosomes on newly replicated DNA is abnormal." [GO:0006335, PomBase:mah] synonym: "abnormal DNA replication-coupled nucleosome assembly" EXACT [PomBase:al] synonym: "abnormal DNA replication-dependent nucleosome assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal DNA replication-dependent nucleosome assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2019-11-19T14:42:28Z [Term] id: FYPO:0007161 name: resistance to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to oxidative stress." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to osmotic stress in culture. If you have assayed the response to osmotic stress at the subcellular or molecular level, consider annotating to 'abnormal cellular response to osmotic stress' (FYPO:0000193). synonym: "increased growth during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "resistance to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2019-11-21T11:44:09Z [Term] id: FYPO:0007162 name: increased duration of nuclear fusion during mating def: "A cellular process phenotype in which the duration of karyogamy involved in conjugation with cellular fusion is longer than normal." [PomBase:mah] synonym: "increased duration of karyogamy" EXACT [PomBase:mah] synonym: "increased duration of karyogamy involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "prolonged nuclear fusion during mating" EXACT [PomBase:mah] is_a: FYPO:0000510 ! abnormal nuclear fusion during mating created_by: midori creation_date: 2019-11-21T11:45:38Z [Term] id: FYPO:0007163 name: abnormal microtubule-based movement def: "A cellular process phenotype in which microtubule-based movement is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2019-11-21T11:58:42Z [Term] id: FYPO:0007164 name: decreased microtubule sliding def: "A cellular process phenotype in which the occurrence of microtubule sliding, i.e. movement of one microtubule along another microtubule, is decreased." [GO:0051012, PomBase:mah] is_a: FYPO:0007163 ! abnormal microtubule-based movement created_by: midori creation_date: 2019-11-21T12:03:45Z [Term] id: FYPO:0007165 name: abolished protein localization to cell cortex during meiotic cell cycle def: "A cell phenotype in which the localization of a protein to the cell cortex does not occur during the meiotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein absent from cell cortex during meiotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to cell cortex abolished during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000930 ! abolished protein localization to cell cortex during vegetative growth created_by: midori creation_date: 2019-11-21T12:06:36Z [Term] id: FYPO:0007166 name: abolished protein localization to cell cortex during meiotic prophase I def: "A cell phenotype in which the localization of a protein to the cell cortex does not occur during prophase of the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to cell cortex during prophase I" EXACT [PomBase:mah] synonym: "protein absent from cell cortex during meiotic prophase I" RELATED [PomBase:mah] synonym: "protein localization to cell cortex abolished during meiotic prophase I" EXACT [PomBase:mah] is_a: FYPO:0007165 ! abolished protein localization to cell cortex during meiotic cell cycle created_by: midori creation_date: 2019-11-21T12:22:10Z [Term] id: FYPO:0007167 name: normal protein localization to cell cortex during meiotic prophase I def: "A cell phenotype in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type) during prophase of the first meiotic nuclear division." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell cortex during meiotic prophase I" EXACT [PomBase:mah] synonym: "normal protein localisation to cell cortex during prophase I" EXACT [PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis created_by: midori creation_date: 2019-11-21T12:28:29Z [Term] id: FYPO:0007168 name: abolished microtubule attachment to cell cortex def: "A cell phenotype in which the attachment of microtubules to the cell cortex does not occur." [PomBase:mah] synonym: "abolished microtubule anchoring at cell cortex" EXACT [PomBase:mah] synonym: "abolished microtubule cortical anchor activity" EXACT [GO:0106006] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2019-11-21T12:33:39Z [Term] id: FYPO:0007169 name: normal microtubule bundle formation during mitotic spindle assembly def: "A cellular process phenotype in which microtubule bundle formation that takes place as part of mitotic spindle assembly, and which normally results in a parallel arrangement of microtubules, is normal (i.e. indistinguishable from wild type)." [GO:0001578, PMID:18061564, PomBase:mah] synonym: "normal microtubule array formation during mitotic spindle assembly" RELATED [PomBase:vw] synonym: "normal microtubule bundle formation in spindle during mitotic prophase" RELATED [PomBase:vw] synonym: "normal microtubule bundle formation involved in mitotic spindle assembly" EXACT [PomBase:mah] synonym: "normal mitotic spindle microtubule bundling during prophase" EXACT [PomBase:vw] synonym: "normal mitotic spindle microtubule bundling during spindle assembly" RELATED [PomBase:vw] is_a: FYPO:0000297 ! microtubule cytoskeleton organization phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-11-21T12:37:19Z [Term] id: FYPO:0007170 name: normal number of nuclei in ascus def: "A phenotype an ascus contains four nuclei, as in wild type." [PMID:20826461, PomBase:mah] comment: Note that in this phenotype, spores may or may not form normally around the four nuclei. is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2019-11-21T12:41:13Z [Term] id: FYPO:0007171 name: normal cell cortex morphology during meiotic prophase I def: "A physical cellular phenotype in which the size, shape, and structure of the cell cortex are normal during prophase of the first meiotic nuclear division. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "normal cell cortex morphology during prophase I" EXACT [PomBase:mah] synonym: "normal cell cortex morphology during prophase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0001231 ! normal cell cortex morphology created_by: midori creation_date: 2019-12-09T14:07:55Z [Term] id: FYPO:0007172 name: stationary phase viability unaffected by micafungin def: "A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of micafungin. Normally, wild-type cell populations survive longer in the presence of micafungin than in its absence." [PMID:31601154, PomBase:mah] comment: Although each cell has a replicative lifespan in that it divides a certain number of times and then dies, replicative lifespan is often measured at the population level, where it is defined by the number of generations at which 50% of the starting cells are dead. synonym: "chronological lifespan unaffected by micafungin" RELATED [PomBase:mah] synonym: "loss of chronological lifespan extension by micafungin" RELATED [PomBase:mah] synonym: "loss of stationary phase viability extension in presence of micafungin" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2019-12-09T14:47:41Z [Term] id: FYPO:0007173 name: decreased mitotic checkpoint complex binding def: "A molecular function phenotype in which occurrence of mitotic checkpoint complex binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:28366744, PomBase:mah] synonym: "decreased MCC binding" EXACT [GO:0033597] synonym: "reduced mitotic checkpoint complex binding" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein-protein interaction is_a: FYPO:0003591 ! abnormal protein complex binding created_by: midori creation_date: 2019-12-09T14:48:54Z [Term] id: FYPO:0007174 name: abnormal protein localization to kinetochore during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal during interphase of the mitotic cell cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the kinetochore and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to kinetochore during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to kinetochore during interphase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001268 ! abnormal protein localization to kinetochore during vegetative growth created_by: midori creation_date: 2019-12-09T14:57:54Z [Term] id: FYPO:0007175 name: abolished protein localization to plasma membrane at cell division site during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abolished during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to plasma membrane at cell division site during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization in plasma membrane at cell division site during mitotic interphase" EXACT [GO:0072659] synonym: "abolished protein localization to cell membrane at cell division site during mitotic interphase" EXACT [GO:0005886] synonym: "abolished protein localization to plasma membrane at cell division site during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to plasma membrane at cell division site during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein localization to plasma membrane at cell division site abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0006936 ! abolished protein localization to plasma membrane at cell division site during vegetative growth created_by: midori creation_date: 2019-12-09T15:08:42Z [Term] id: FYPO:0007176 name: abolished protein localization to plasma membrane at cell division site during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abolished during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to plasma membrane at cell division site during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization in plasma membrane at cell division site during mitosis" EXACT [GO:0072659] synonym: "abolished protein localization to cell membrane at cell division site during mitosis" EXACT [GO:0005886] synonym: "abolished protein localization to plasma membrane at cell division site during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to plasma membrane at cell division site during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to plasma membrane at cell division site during mitotic nuclear division" EXACT [GO:0140014] synonym: "protein localization to plasma membrane at cell division site abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0006936 ! abolished protein localization to plasma membrane at cell division site during vegetative growth created_by: midori creation_date: 2019-12-09T15:18:07Z [Term] id: FYPO:0007177 name: abolished protein localization to medial cortex during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abolished during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortex during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortex during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortex during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein localization to medial ring during mitotic interphase" EXACT [GO:0031097, GO:0071574] synonym: "protein localization to medial cortex abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0002555 ! abolished protein localization to medial cortex during vegetative growth created_by: midori creation_date: 2019-12-09T15:20:15Z [Term] id: FYPO:0007178 name: abolished protein localization to medial cortex during mitosis def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abolished during mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to medial cortex during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortex during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to medial cortex during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to medial cortex during mitotic nuclear division" EXACT [GO:0140014] synonym: "abolished protein localization to medial ring during mitosis" EXACT [GO:0031097, GO:0071574] synonym: "protein localization to medial cortex abolished during mitosis" EXACT [PomBase:mah] is_a: FYPO:0002555 ! abolished protein localization to medial cortex during vegetative growth created_by: midori creation_date: 2019-12-09T15:20:23Z [Term] id: FYPO:0007179 name: mislocalized protein distributed in cell cortex during mitotic interphase def: "A cell phenotype in which a protein is detected abnormally distributed throughout the cell cortex during interphase of the mitotic cell cycle. The protein may normally be restricted to part of the cell cortex, or not normally located in the cell cortex at all." [PomBase:mah] comment: This term can be used for protein that do not normally localize to discrete cytoplasmic regions, or for proteins that do normally show punctate localization but with such localization increased in a mutant. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein distributed in cell cortex during mitotic interphase" EXACT [PomBase:mah] synonym: "mislocalized protein distributed at cell surface during mitotic interphase" RELATED [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006636 ! mislocalized protein distributed in cell cortex created_by: midori creation_date: 2019-12-09T15:25:30Z [Term] id: FYPO:0007180 name: mislocalized protein distributed in cell cortex during mitosis def: "A cell phenotype in which a protein is detected abnormally distributed throughout the cell cortex during mitosis. The protein may normally be restricted to part of the cell cortex, or not normally located in the cell cortex at all." [PomBase:mah] comment: This term can be used for protein that do not normally localize to discrete cytoplasmic regions, or for proteins that do normally show punctate localization but with such localization increased in a mutant. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein distributed in cell cortex during mitosis" EXACT [PomBase:mah] synonym: "mislocalized protein distributed at cell surface during mitosis" RELATED [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during mitotic M phase" RELATED [PomBase:mah] synonym: "mislocalized protein distributed in cell cortex during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0006636 ! mislocalized protein distributed in cell cortex created_by: midori creation_date: 2019-12-09T15:29:21Z [Term] id: FYPO:0007181 name: normal protein localization to cell division site during mitotic anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is normal (i.e. indistinguishable from wild type) during anaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell division site during mitotic anaphase" EXACT [PomBase:mah] synonym: "normal protein localization to cell division site during anaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein recruitment to cell division site during mitotic anaphase" RELATED [PomBase:vw] is_a: FYPO:0002442 ! normal protein localization to cell division site created_by: midori creation_date: 2019-12-09T15:37:10Z [Term] id: FYPO:0007182 name: decreased cytoplasmic microtubule depolymerization at plus end at cell tip def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule, occurs to a lesser extent than normal at the plus end of the microtubule at the cell tip. Normally, rapid depolymerization takes place when the growing plus end of the microtubule reaches the cell tip." [GO:0070462, PMID:31276301, PomBase:mah] synonym: "decreased cytoplasmic microtubule depolymerisation at plus end at cell tip" EXACT [PomBase:mah] synonym: "decreased cytoplasmic microtubule depolymerization at plus end at cell end" EXACT [PomBase:mah] synonym: "decreased cytoplasmic microtubule depolymerization at plus end at cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytoplasmic microtubule depolymerization at plus end at cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule catastrophe at cell tip" RELATED [PomBase:vw] synonym: "decreased microtubule plus end shrinkage at cell tip" RELATED [PomBase:vw] synonym: "decreased plus-end specific microtubule depolymerization at cell tip" EXACT [GO:0070462] synonym: "reduced cytoplasmic microtubule depolymerization at plus end at cell tip" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth created_by: midori creation_date: 2019-12-09T15:39:43Z [Term] id: FYPO:0007183 name: increased protein kinase activity during mitotic interphase def: "A molecular function phenotype in which the observed rate of a protein kinase activity is increased during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "increased protein kinase activity during interphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0002700 ! increased protein kinase activity created_by: midori creation_date: 2019-12-09T15:46:03Z [Term] id: FYPO:0007184 name: increased protein kinase activity during mitosis def: "A molecular function phenotype in which the observed rate of a protein kinase activity is increased during mitosis." [PomBase:mah] synonym: "increased protein kinase activity during mitotic M phase" RELATED [PomBase:mah] synonym: "increased protein kinase activity during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0002700 ! increased protein kinase activity created_by: midori creation_date: 2019-12-09T15:47:03Z [Term] id: FYPO:0007185 name: abnormal cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea def: "A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested at the mitotic G2/M phase transition during a cellular response to hydroxyurea." [PMID:28377506, PomBase:mah] comment: This term can be used for any circumstances in which cells are starved for nitrogen. Note that cells may enter G0 (quiescence) when subjected to prolonged nitrogen starvation; this term is not restricted to G0. synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition during cellular response to HU" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic G2 phase during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "abolished mitotic G2/M phase transition during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "mitotic G2 phase arrest during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition is_a: FYPO:0001933 ! abnormal mitotic cell cycle regulation during cellular response to hydroxyurea created_by: midori creation_date: 2019-12-11T11:48:52Z [Term] id: FYPO:0007186 name: increased cellular reactive oxygen species level during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal during a cellular response to hydroxyurea." [PomBase:mah] synonym: "increased cellular reactive oxygen species accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to HU" EXACT [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular ROS accumulation during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "increased cellular ROS level during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "increased ROS accumulation during cellular response to hydroxyurea" RELATED [PomBase:al] is_a: FYPO:0003004 ! increased cellular reactive oxygen species level during vegetative growth created_by: midori creation_date: 2019-12-11T11:52:13Z [Term] id: FYPO:0007187 name: decreased cellular heme level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any heme measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular haem level" EXACT [CHEBI:30413] synonym: "decreased cellular heme level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular heme level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular heme level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2019-12-11T11:54:00Z [Term] id: FYPO:0007188 name: normal growth on sampangine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sampangine." [PomBase:mah] synonym: "normal cell population growth in presence of sampangine" EXACT [PomBase:mah] synonym: "normal cell population growth on sampangine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on sampangine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2019-12-11T11:55:38Z [Term] id: FYPO:0007189 name: sensitive to sampangine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sampangine. Cells stop growing (and may die) at a concentration of sampangine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sampangine" EXACT [PomBase:mah] synonym: "sensitive to sampangine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sampangine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2019-12-11T11:56:19Z [Term] id: FYPO:0007190 name: increased sister chromatid cohesion along chromosome arms during mitotic interphase def: "A cellular process phenotype in which cohesion between sister chromatids is increased along the length of the chromosome arms during interphase of the mitotic cell cycle." [PMID:31483748, PomBase:mah] synonym: "increased mitotic sister chromatid cohesion along chromosome arms during interphase" EXACT [PomBase:mah] synonym: "increased sister chromatid cohesion along chromosome arms during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased sister chromatid cohesion along chromosome arms during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006521 ! abnormal mitotic sister chromatid cohesion created_by: midori creation_date: 2019-12-11T13:31:43Z [Term] id: FYPO:0007191 name: increased duration of Rad52 focus presence during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which sites at which the protein Rad52 accumulates remain present for longer than normal." [PMID:31483748, PomBase:mah] synonym: "delayed peak level of Rad52 foci during vegetative growth" RELATED [PMID:27098497] synonym: "increased duration of Rad22 focus presence during vegetative growth" EXACT [PMID:22927644] synonym: "increased duration of Rad52 focus presence during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased persistence of Rad52 foci during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged Rad52 focus presence during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2019-12-11T13:40:03Z [Term] id: FYPO:0007192 name: abolished spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which rapid, back-and-forth movement of the mitotic spindle pole body (SPB), and associated chromosome movement, do not occur. Normally, SPB oscillation occurs during mitotic interphase (as well as prophase) but is restricted to a small space." [PMID:31483748, PomBase:mah] synonym: "abolished mitotic SPB oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "abolished spindle pole body-led chromosome movement during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle pole body oscillation abolished during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0005348 ! abnormal spindle pole body-led chromosome movement during mitotic interphase created_by: midori creation_date: 2019-12-16T11:12:38Z [Term] id: FYPO:0007193 name: small fragmented mitochondria def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are smaller than normal." [PomBase:mah] synonym: "small mitochondria during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small mitochondria during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology created_by: midori creation_date: 2019-12-16T11:26:00Z [Term] id: FYPO:0007194 name: mitochondria present in increased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more mitochondria than normal." [PomBase:mah] synonym: "extra mitochondria during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of mitochondria during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondria present in increased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondria present in increased numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2019-12-16T11:26:19Z [Term] id: FYPO:0007195 name: large mitochondria def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are larger than normal." [PomBase:mah] synonym: "enlarged mitochondria" EXACT [PomBase:mah] synonym: "large mitochondria during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large mitochondria during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology created_by: midori creation_date: 2019-12-16T11:44:15Z [Term] id: FYPO:0007196 name: decreased mitochondrial fission def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, occurs to a lower extent than normal." [PMID:30602572, PomBase:mah] synonym: "decreased frequency of mitochondrial fission" EXACT [PomBase:vw] synonym: "decreased mitochondrial division" EXACT [GO:0000266, PomBase:mah] synonym: "decreased mitochondrial fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial fission during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitochondrial proliferation" RELATED [GO:0000266, PomBase:mah] synonym: "reduced mitochondrial fission" EXACT [PomBase:mah] is_a: FYPO:0004340 ! abnormal mitochondrial fission created_by: midori creation_date: 2019-12-16T11:47:00Z [Term] id: FYPO:0007197 name: increased mitochondrial fission def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, occurs to a greater extent than normal." [PMID:30602572, PomBase:mah] synonym: "increased frequency of mitochondrial fission" EXACT [PomBase:vw] synonym: "increased mitochondrial division" EXACT [GO:0000266, PomBase:mah] synonym: "increased mitochondrial fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitochondrial fission during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitochondrial proliferation" RELATED [GO:0000266, PomBase:mah] is_a: FYPO:0004340 ! abnormal mitochondrial fission created_by: midori creation_date: 2019-12-16T11:50:24Z [Term] id: FYPO:0007198 name: normal mitotic centromeric sister chromatid cohesion def: "A cellular process phenotype in which cohesion between centromeres of sister chromatids is normal (i.e. indistinguishable from wild type)." [GO:0071962, PomBase:mah] synonym: "normal centromeric sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitotic centromeric sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitotic chromosome cohesion at centromere" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid cohesion at centromere" EXACT [PomBase:mah] synonym: "normal sister chromatid cohesion at centromere during mitosis" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2019-12-16T13:47:09Z [Term] id: FYPO:0007199 name: decreased splicing of mRNA introns with nonconsensus cis-splicing sequences def: "A cellular process phenotype in which the occurrence of mRNA splicing via the spliceosome of introns that have one or more deviations from optimal cis-splicing sequences is decreased. Nonconsensus features may include a longer distance between the branch point and 3' splice site, lacking a polypyrimidine tract, or use of alternative 5' splice sites." [PMID:28446597, PomBase:mah] synonym: "decreased mRNA splicing, via spliceosome, introns with nonconsensus cis-splicing sequences" EXACT [PomBase:mah] synonym: "decreased nuclear mRNA splicing, via spliceosome, introns with nonconsensus cis-splicing sequences" EXACT [PomBase:mah] synonym: "decreased splicing of mRNA introns with nonconsensus cis-splicing sequences" BROAD [PomBase:al] synonym: "decreased splicing of mRNA introns with nonconsensus cis-splicing sequences during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased splicing of mRNA introns with nonconsensus cis-splicing sequences during vegetative growth" EXACT [PomBase:mah] synonym: "reduced splicing of mRNA introns with nonconsensus cis-splicing sequences" EXACT [PomBase:mah] is_a: FYPO:0003244 ! decreased mRNA splicing, via spliceosome, intron-specific created_by: midori creation_date: 2019-12-16T13:54:20Z [Term] id: FYPO:0007200 name: aggregated actin cortical patches during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches cluster together more than normal during interphase of the mitotic cell cycle." [PMID:30201262, PomBase:mah] synonym: "actin cortical patch aggregation during mitotic interphase during vegetative growth" RELATED [PomBase:mah] synonym: "aggregated actin cortical patch distribution during mitotic interphase" EXACT [PomBase:vw] synonym: "aggregated actin cortical patch localisation during mitotic interphase" EXACT [PomBase:mah] synonym: "aggregated actin cortical patch localization during mitotic interphase" EXACT [PomBase:vw] synonym: "aggregated actin cortical patches during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "aggregated actin patches during mitotic interphase" EXACT [PomBase:mah] synonym: "aggregated F-actin patches during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0005430 ! aggregated actin cortical patches during vegetative growth created_by: midori creation_date: 2019-12-16T13:57:23Z [Term] id: FYPO:0007201 name: decreased rate of actin cortical patch localization to cell division site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cortical patch localization to the site of cell division is decreased." [PMID:30201262, PomBase:mah] synonym: "decreased rate of actin cortical patch localisation to cell division site" EXACT [PomBase:mah] synonym: "decreased rate of actin cortical patch localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of actin cortical patch localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of actin cortical patch movement to cell division site" RELATED [PomBase:mah] synonym: "decreased rate of actin patch localization to cell division site" EXACT [PomBase:vw] synonym: "reduced rate of actin cortical patch localization to cell division site" EXACT [PomBase:mah] is_a: FYPO:0006176 ! decreased rate of actin cortical patch localization created_by: midori creation_date: 2019-12-16T13:59:27Z [Term] id: FYPO:0007202 name: normal rDNA spacer replication fork barrier binding def: "A molecular function phenotype in which occurrence of DNA binding at an rDNA spacer replication fork barrier by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PMID:18794373, PomBase:mah] synonym: "normal DNA binding at rDNA spacer replication fork barrier" EXACT [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2019-12-17T11:17:35Z [Term] id: FYPO:0007203 name: decreased rDNA spacer replication fork barrier binding def: "A molecular function phenotype in which occurrence of DNA binding at an rDNA spacer replication fork barrier by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:18794373, PomBase:mah] synonym: "decreased DNA binding at rDNA spacer replication fork barrier" EXACT [PomBase:mah] synonym: "reduced rDNA spacer replication fork barrier binding" EXACT [PomBase:mah] is_a: FYPO:0000658 ! decreased DNA binding created_by: midori creation_date: 2019-12-17T11:20:11Z [Term] id: FYPO:0007204 name: abolished rDNA spacer replication fork barrier binding def: "A molecular function phenotype in which DNA binding at an rDNA spacer replication fork barrier by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:18794373, PomBase:mah] synonym: "abolished DNA binding at rDNA spacer replication fork barrier" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2019-12-17T11:21:06Z [Term] id: FYPO:0007205 name: normal replication fork arrest at rDNA repeats def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at sites within the eukaryotic rDNA repeat spacer is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal replication fork arrest at rDNA repeats during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal replication fork arrest at rDNA repeats during vegetative growth" EXACT [PomBase:mah] synonym: "normal replication fork arrest at ribosomal DNA repeats" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0008191 ! normal replication fork arrest created_by: midori creation_date: 2019-12-17T11:23:39Z [Term] id: FYPO:0007206 name: abolished replication fork arrest at rDNA repeats def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic rDNA repeat spacer does not occur." [PomBase:mah] synonym: "abolished replication fork arrest at rDNA repeats during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished replication fork arrest at rDNA repeats during vegetative growth" EXACT [PomBase:mah] synonym: "abolished replication fork arrest at ribosomal DNA repeats" EXACT [PomBase:mah] synonym: "replication fork arrest at rDNA repeats abolished" EXACT [PomBase:mah] is_a: FYPO:0003089 ! abnormal replication fork arrest at rDNA repeats created_by: midori creation_date: 2019-12-17T11:24:59Z [Term] id: FYPO:0007207 name: growth auxotrophic for aspartate def: "Auxotrophy in which a cell is unable to synthesize aspartate, and therefore requires aspartate in the medium for vegetative cell growth." [PomBase:mah] synonym: "aspartate auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for aspartate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "growth auxotrophic for aspartate during vegetative growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for aspartatic acid" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2019-12-17T11:26:02Z [Term] id: FYPO:0007208 name: normal microtubule bundle length during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which microtubule bundle length is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal interphase microtubule bundle length" EXACT [PomBase:vw] synonym: "normal microtubule bundle length during interphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth created_by: midori creation_date: 2019-12-18T10:40:25Z [Term] id: FYPO:0007209 name: decreased sister chromatid cohesion along chromosome arms during mitotic interphase def: "A cellular process phenotype in which cohesion between sister chromatids is decreased along the length of the chromosome arms during interphase of the mitotic cell cycle." [PMID:31483748, PomBase:mah] synonym: "decreased mitotic sister chromatid cohesion along chromosome arms during interphase" EXACT [PomBase:mah] synonym: "decreased sister chromatid cohesion along chromosome arms during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased sister chromatid cohesion along chromosome arms during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced sister chromatid cohesion along chromosome arms during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0006521 ! abnormal mitotic sister chromatid cohesion created_by: midori creation_date: 2019-12-19T11:28:30Z [Term] id: FYPO:0007210 name: normal mitochondrial volume def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total volume of all mitochondria in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitochondrial volume during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal mitochondrial volume during vegetative growth" EXACT [PomBase:mah] synonym: "normal total mitochondrial volume" EXACT [PomBase:mah] is_a: FYPO:0003896 ! normal mitochondrial morphology created_by: midori creation_date: 2020-01-06T15:58:14Z [Term] id: FYPO:0007211 name: premature actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring assembly begins earlier than normal. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins." [PMID:15184401, PomBase:mah] synonym: "advanced actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring formation" RELATED [PomBase:mah] synonym: "premature contractile ring assembly" EXACT [PomBase:vw] synonym: "premature cytokinetic contractile ring assembly" EXACT [PomBase:vw] synonym: "premature mitotic actomyosin contractile ring assembly" EXACT [GO:1902404, PomBase:mah] synonym: "premature mitotic contractile ring assembly" EXACT [PomBase:vw] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly created_by: midori creation_date: 2020-01-06T16:04:05Z [Term] id: FYPO:0007212 name: decreased chromatin silencing at heterochromatin island def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at heterochromatin islands is decreased." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "decreased chromatin silencing at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin silencing at heterochromatin island during vegetative growth" EXACT [PomBase:mah] synonym: "reduced chromatin silencing at heterochromatin island" EXACT [PomBase:mah] is_a: FYPO:0002353 ! decreased chromatin silencing created_by: midori creation_date: 2020-01-07T11:14:51Z [Term] id: FYPO:0007213 name: decreased histone H3-K9 dimethylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a lower extent than normal." [PMID:29214404, PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at heterochromatin island during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at heterochromatin island during vegetative growth" EXACT [PomBase:vw] synonym: "decreased histone H3K9me2 at heterochromatin island during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 dimethylation at heterochromatin island during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at heterochromatin island during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation during vegetative growth created_by: midori creation_date: 2020-01-07T11:17:18Z [Term] id: FYPO:0007214 name: abolished protein localization to heterochromatin island def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more heterochromatin islands is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at heterochromatin island during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to chromatin at heterochromatin island abolished" EXACT [PomBase:mah] is_a: FYPO:0008418 ! abnormal protein localization to heterochromatin island created_by: midori creation_date: 2020-01-07T11:27:05Z [Term] id: FYPO:0007215 name: abolished protein localization to chromatin at lncRNA gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more lncRNA genes is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at lncRNA gene during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at lncRNA gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at long non-coding RNA gene" EXACT [PomBase:mah, SO:0002127] synonym: "protein localization to chromatin at lncRNA gene abolished" EXACT [PomBase:mah] is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth created_by: midori creation_date: 2020-01-07T11:28:04Z [Term] id: FYPO:0007216 name: abolished protein localization to chromatin at MCB promoters during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is abolished during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin at MCB promoters during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB promoters during cellular response to HU" EXACT [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB promoters during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB target genes during cellular response to hydroxyurea" RELATED [PomBase:mah] synonym: "abolished protein localization to chromatin at MCB-containing promoters during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "protein localization to chromatin at MCB promoters during vegetative growth abolished during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0005460 ! abolished protein localization to chromatin at MCB promoters created_by: midori creation_date: 2020-01-07T11:43:16Z [Term] id: FYPO:0007217 name: decreased histone H3-K9 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal." [PMID:31260531, PomBase:mah] synonym: "decreased histone H3-K9 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 acetylation at protein coding gene during vegetative growth" EXACT [GO:0043970, PomBase:mah] synonym: "reduced histone H3-K9 acetylation at protein coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001442 ! decreased histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2020-01-07T11:45:55Z [Term] id: FYPO:0007218 name: decreased histone H3-K18 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 18 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal." [PMID:31260531, PomBase:mah] synonym: "decreased histone H3-K18 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K18 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K18 acetylation at protein coding gene during vegetative growth" EXACT [GO:0043971, PomBase:mah] synonym: "reduced histone H3-K18 acetylation at protein coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002362 ! decreased histone H3 acetylation during vegetative growth created_by: midori creation_date: 2020-01-07T11:48:21Z [Term] id: FYPO:0007219 name: normal histone H3-K14 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type)." [PMID:31260531, PomBase:mah] synonym: "normal histone H3-K14 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K14 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K14 acetylation at protein coding gene during vegetative growth" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0003224 ! normal histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2020-01-07T11:55:41Z [Term] id: FYPO:0007220 name: normal histone H3-K9 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type)." [PMID:31260531, PomBase:mah] synonym: "normal histone H3-K9 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K9 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K9 acetylation at protein coding gene during vegetative growth" EXACT [GO:0043970] is_a: FYPO:0003223 ! normal histone H3-K9 acetylation during vegetative growth created_by: midori creation_date: 2020-01-07T11:58:46Z [Term] id: FYPO:0007221 name: normal histone H3-K18 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 18 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type)." [PMID:31260531, PomBase:mah] synonym: "normal histone H3-K18 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3-K18 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K18 acetylation at protein coding gene during vegetative growth" EXACT [GO:0043971] is_a: FYPO:0003221 ! normal histone acetylation during vegetative growth created_by: midori creation_date: 2020-01-07T12:00:04Z [Term] id: FYPO:0007222 name: decreased histone H3-K14 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal." [PMID:31260531, PomBase:mah] synonym: "decreased histone H3-K14 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K14 acetylation at protein coding gene during vegetative growth" EXACT [GO:0044154, PomBase:mah] synonym: "reduced histone H3-K14 acetylation at protein coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001458 ! decreased histone H3-K14 acetylation during vegetative growth created_by: midori creation_date: 2020-01-07T12:01:51Z [Term] id: FYPO:0007223 name: decreased establishment of chromatin silencing at centromere outer repeat region def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment of chromatin silencing at centromere outer repeat regions is decreased." [PMID:31822915, PomBase:mah] synonym: "decreased establishment of chromatin silencing at centromere outer repeat at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased establishment of chromatin silencing at centromere outer repeat at centromeric outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased establishment of chromatin silencing at centromere outer repeat at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased establishment of chromatin silencing at centromere outer repeat at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased establishment of chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced establishment of chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002346 ! abnormal chromatin silencing at centromere outer repeat created_by: midori creation_date: 2020-01-07T13:04:58Z [Term] id: FYPO:0007224 name: decreased heterochromatin assembly at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is decreased in centromere outer repeat regions. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent." [GO:0031507, PMID:31822915, PomBase:mah] synonym: "decreased establishment of heterochromatin at centromere outer repeat" EXACT [PMID:31822915] synonym: "decreased heterochromatin assembly at centromere outer repeat at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "decreased heterochromatin assembly at centromere outer repeat at centromeric outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased heterochromatin assembly at centromere outer repeat at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased heterochromatin assembly at centromere outer repeat at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "decreased heterochromatin assembly at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased heterochromatin formation at centromere outer repeat during vegetative growth" EXACT [GO:0031507, PomBase:mah] synonym: "reduced heterochromatin assembly at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003098 ! abnormal heterochromatin assembly at centromere outer repeat during vegetative growth created_by: midori creation_date: 2020-01-07T13:08:49Z [Term] id: FYPO:0007225 name: normal heterochromatin assembly by small RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is normal (i.e. indistinguishable from wild type). Small RNA-mediated heterochromatin assembly results in transcriptional silencing." [PomBase:mah] synonym: "normal chromatin silencing by small RNA" EXACT [PomBase:mah] synonym: "normal heterochromatin assembly by small RNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal heterochromatin assembly by small RNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNAi-mediated chromatin silencing" EXACT [PomBase:al] is_a: FYPO:0002335 ! normal chromatin silencing created_by: midori creation_date: 2020-01-07T13:13:40Z [Term] id: FYPO:0007226 name: normal chromatin silencing at heterochromatin island def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at one or more heterochromatin islands is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "normal chromatin silencing at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal chromatin silencing at heterochromatin island during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002335 ! normal chromatin silencing created_by: midori creation_date: 2020-01-07T13:15:00Z [Term] id: FYPO:0007227 name: increased number of R-loops at centromere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal in centromeric regions." [PMID:31822915, PomBase:mah] synonym: "increased level of DNA:RNA hybrids at centromere" EXACT [PomBase:al] synonym: "increased level of RNA-DNA hybrids at centromere" EXACT [] synonym: "increased level of RNA-DNA hybrids at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of RNA-DNA hybrids at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA-DNA hybrid level at centromere" EXACT [PomBase:mah] is_a: FYPO:0007901 ! increased number of R-loops created_by: midori creation_date: 2020-01-07T13:19:40Z [Term] id: FYPO:0007228 name: abnormal 3'-deoxyribose phosphate lyase activity def: "A molecular function phenotype in which the observed rate of 3'-deoxyribose phosphate lyase activity is abnormal." [PomBase:mah] synonym: "abnormal 3'-dRP lyase activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2020-01-20T14:22:07Z [Term] id: FYPO:0007229 name: abolished 3'-deoxyribose phosphate lyase activity def: "A molecular function phenotype in which 3'-deoxyribose phosphate lyase activity is absent." [PomBase:mah] synonym: "3'-deoxyribose phosphate lyase activity abolished" EXACT [PomBase:mah] synonym: "abolished 3'-dRP lyase activity" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0007228 ! abnormal 3'-deoxyribose phosphate lyase activity created_by: midori creation_date: 2020-01-20T14:22:15Z [Term] id: FYPO:0007230 name: spindle-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in the form of a spindle, i.e. both cell tips are narrower and more pointed than normal." [PMID:22137473, PomBase:mah] synonym: "spindle-shaped cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "spindle-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002196 ! abnormal vegetative cell shape created_by: midori creation_date: 2020-01-20T14:31:39Z [Term] id: FYPO:0007231 name: viable spindle-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell is viable, and grows in the form of a spindle." [PMID:22137473, PomBase:mah] synonym: "viable spindle-shaped cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable spindle-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable spindle-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape is_a: FYPO:0007230 ! spindle-shaped cell relationship: has_part FYPO:0007230 ! spindle-shaped cell created_by: midori creation_date: 2020-01-20T14:34:25Z [Term] id: FYPO:0007232 name: abnormal regulation of mitotic DNA replication initiation from early origin def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of mitotic DNA replication from early-firing origins is abnormal." [PMID:22279046, PomBase:mah] synonym: "abnormal regulation of DNA replication initiation from early origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal regulation of early origin firing timing" RELATED [PomBase:mah] synonym: "abnormal regulation of mitotic DNA replication initiation at early origin" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic DNA replication initiation from early origin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of mitotic DNA replication initiation from early replication origin" EXACT [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of mitotic DNA replication initiation created_by: midori creation_date: 2020-01-20T14:52:08Z [Term] id: FYPO:0007233 name: delayed onset of mitotic DNA replication initiation from early origin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins later than normal at origins that normally fire early." [PMID:22279046, PomBase:mah] synonym: "delayed mitotic DNA replication initiation from early origin" EXACT [PomBase:mah] synonym: "delayed onset of DNA replication initiation from early origin during mitotic cell cycle" EXACT [PomBase:mah] synonym: "delayed onset of DNA replication initiation from early origin during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of mitotic DNA replication initiation at early origin" EXACT [PomBase:mah] synonym: "delayed onset of mitotic DNA replication initiation from early replication origin" EXACT [PomBase:mah] is_a: FYPO:0006031 ! delayed onset of mitotic DNA replication initiation relationship: output_of FYPO:0007232 ! abnormal regulation of mitotic DNA replication initiation from early origin created_by: midori creation_date: 2020-01-20T15:17:37Z [Term] id: FYPO:0007234 name: normal protein localization to centromere central core def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the central core of the centromeric region of a chromosome is normal (i.e. indistinguishable from wild type." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to centromere central core" EXACT [PomBase:mah] synonym: "normal protein localization to centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to centromere central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002574 ! normal protein localization to centromere during vegetative growth created_by: midori creation_date: 2020-01-20T15:32:36Z [Term] id: FYPO:0007235 name: decreased protein localization to chromatin at early replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at early replication origins (i.e. origins that normally fire early in S phase) is decreased." [PMID:22279046, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at early replication origin" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at early origin" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at early replication origin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to early replication origin during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at early replication origin" EXACT [PomBase:mah] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2020-01-20T15:43:45Z [Term] id: FYPO:0007236 name: delayed onset of protein localization to chromatin at early replication origin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at early replication origins (i.e. origins that normally fire early in S phase) begins later than normal." [PMID:22279046, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to chromatin at early replication origin" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to chromatin at early origin" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to chromatin at early replication origins during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to chromatin at early replication origins during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to chromatin at early replication origin" EXACT [PomBase:mah] is_a: FYPO:0006734 ! delayed onset of protein localization to chromatin at replication origin created_by: midori creation_date: 2020-01-20T15:44:04Z [Term] id: FYPO:0007237 name: increased meiotic DNA double-strand break formation near existing double-strand break def: "A cellular process phenotype in which the frequency at which two double-strand breaks (DSBs) form close to each other during meiosis I is increased." [PMID:30217891, PomBase:mah] synonym: "decreased distance between meiotic DSBs" EXACT [PomBase:mah] synonym: "decreased DSB interference" EXACT [PMID:30217891] is_a: FYPO:0003564 ! abnormal meiotic DNA double-strand break formation created_by: midori creation_date: 2020-01-29T14:26:19Z [Term] id: FYPO:0007238 name: increased meiotic double crossover formation def: "A cellular process phenotype in which the occurrence of two crossovers within a given interval during meiosis I is higher than normal." [PMID:30217891, PomBase:mah] synonym: "decreased crossover interference" EXACT [PMID:30217891] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2020-01-29T14:32:19Z [Term] id: FYPO:0007239 name: normal protein localization to old growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the old growing cell tip is normal (i.e. indistinguishable from wild type)." [PMID:31719163, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to old growing cell tip" EXACT [PomBase:mah] synonym: "normal protein localization to old growing cell end" EXACT [PomBase:mah] synonym: "normal protein localization to old growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to old growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2020-02-11T14:30:39Z [Term] id: FYPO:0007240 name: abnormal NETO in daughter cells def: "A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) differs between the two daughter cells formed as a result of cell division. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells." [PMID:31719163, PomBase:mah] synonym: "abnormal activation of bipolar cell growth in daughter cells" RELATED [PomBase:mah] synonym: "abnormal cell growth mode switching, monopolar to bipolar, in daughter cells" EXACT [GO:0051523] synonym: "abnormal NETO in daughter cells during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal NETO in daughter cells during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal new end take-off in daughter cells" EXACT [PomBase:mah] synonym: "abnormal switch from monopolar to bipolar cell growth in daughter cells" EXACT [PomBase:mah] is_a: FYPO:0000147 ! abnormal NETO created_by: midori creation_date: 2020-02-11T14:34:12Z [Term] id: FYPO:0007241 name: abolished NETO in cell derived from growing end and premature NETO in cell derived from non-growing end def: "A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is abnormal in both of the daughter cells formed as a result of the division of a mother cell in which NETO did not occur, such that NETO is abolished in the daughter cell that inherits the parent cell's old end, and begins earlier than normal in the daughter cell that inherits parent cell's new end. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells." [PMID:31719163, PomBase:mah] synonym: "abolished cell growth mode switching, monopolar to bipolar in cell derived from growing end and premature cell growth mode switching, monopolar to bipolar in cell derived from non-growing end" EXACT [GO:0051523] synonym: "abolished NETO in cell derived from growing end and premature NETO in cell derived from non-growing end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished NETO in cell derived from growing end and premature NETO in cell derived from non-growing end during vegetative growth" EXACT [PomBase:mah] synonym: "abolished new end take-off in cell derived from growing end and premature new end take-off in cell derived from non-growing end" EXACT [PomBase:mah] synonym: "abolished switch from monopolar to bipolar cell growth in cell derived from growing end and premature switch from monopolar to bipolar cell growth in cell derived from non-growing end" EXACT [PomBase:mah] is_a: FYPO:0007240 ! abnormal NETO in daughter cells created_by: midori creation_date: 2020-02-11T14:37:47Z [Term] id: FYPO:0007242 name: abolished NETO in both daughter cells def: "A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is abolished in both of the daughter cells formed as a result of the division of a mother cell in which NETO did not occur. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells." [PMID:31719163, PomBase:mah] synonym: "abolished activation of bipolar cell growth in both daughter cells" RELATED [PomBase:mah] synonym: "abolished cell growth mode switching, monopolar to bipolar, in both daughter cells" EXACT [GO:0051523] synonym: "abolished NETO in both daughter cells during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished NETO in both daughter cells during vegetative growth" EXACT [PomBase:mah] synonym: "abolished new end take-off in both daughter cells" EXACT [PomBase:mah] synonym: "abolished switch from monopolar to bipolar cell growth in both daughter cells" EXACT [PomBase:mah] is_a: FYPO:0007240 ! abnormal NETO in daughter cells created_by: midori creation_date: 2020-02-11T14:46:24Z [Term] id: FYPO:0007243 name: normal NETO in cell derived from growing end and premature NETO in cell derived from non-growing end def: "A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is normal (i.e. indistinguishable from wild type) in one, and premature in the other, of the daughter cells formed as a result of the division of a mother cell in which NETO did not occurs. NETO is normal in the daughter cell that inherits the parent cell's old end, and begins earlier than normal in the daughter cell that inherits parent cell's new end. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells." [PMID:31719163, PomBase:mah] synonym: "normal activation of bipolar cell growth in cell derived from growing end and premature activation of bipolar cell growth in cell derived from non-growing end" RELATED [PomBase:mah] synonym: "normal cell growth mode switching, monopolar to bipolar in cell derived from growing end and premature cell growth mode switching, monopolar to bipolar in cell derived from non-growing end" EXACT [GO:0051523] synonym: "normal NETO in cell derived from growing end and premature NETO in cell derived from non-growing end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal NETO in cell derived from growing end and premature NETO in cell derived from non-growing end during vegetative growth" EXACT [PomBase:mah] synonym: "normal new end take-off in cell derived from growing end and premature NETO in cell derived from non-growing end" EXACT [PomBase:mah] synonym: "normal switch from monopolar to bipolar cell growth in cell derived from growing end and premature switch from monopolar to bipolar cell growth in cell derived from non-growing end" EXACT [PomBase:mah] is_a: FYPO:0007240 ! abnormal NETO in daughter cells created_by: midori creation_date: 2020-02-11T14:53:32Z [Term] id: FYPO:0007244 name: decreased protein localization to kinetochore during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during metaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to kinetochore during mitotic metaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during metaphase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein localization to kinetochore during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0005215 ! decreased protein localization to kinetochore during mitotic M phase created_by: midori creation_date: 2020-02-12T14:25:17Z [Term] id: FYPO:0007245 name: normal meiotic spindle pole body def: "A physical cellular phenotype in which the meiotic spindle pole bodies are normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation." [PomBase:mah] synonym: "normal meiotic SPB" EXACT [PomBase:mah] synonym: "normal spindle pole body during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component created_by: midori creation_date: 2020-02-12T14:29:43Z [Term] id: FYPO:0007246 name: abolished protein localization to meiotic spindle pole body during anaphase II def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abolished during anaphase of the second meiotic nuclear division." [PMID:20980623, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Use this term for cells in which in which the re-accumulation of some spindle pole body components does not occur at the onset of meiosis I. synonym: "abolished protein localisation to meiotic spindle pole body during anaphase II" EXACT [PomBase:mah] synonym: "abolished protein localization to meiotic SPB during anaphase II" EXACT [PomBase:mah] synonym: "protein localization to meiotic spindle pole body abolished during anaphase II" EXACT [PomBase:mah] is_a: FYPO:0003542 ! abolished protein localization to meiotic spindle pole body created_by: midori creation_date: 2020-02-12T14:36:05Z [Term] id: FYPO:0007247 name: abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation def: "A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic G2 DNA damage checkpoint does not occur during a cellular response to ionizing radiation. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage." [GO:0007095, PMID:9042863, PomBase:mah] synonym: "abolished G2 DNA damage checkpoint during cellular response to ionizing radiation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished mitotic cell cycle G2/M transition DNA damage checkpoint during cellular response to ionizing radiation" EXACT [GO:0007095] synonym: "abolished mitotic G2 DNA damage checkpoint activation during cellular response to ionizing radiation" RELATED [PomBase:mah] synonym: "abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished mitotic G2 DNA damage checkpoint during cellular response to IR" EXACT [PomBase:mah] synonym: "mitotic G2 DNA damage checkpoint abolished during cellular response to ionizing radiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004259 ! abolished mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2020-02-17T11:24:33Z [Term] id: FYPO:0007248 name: decreased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation def: "A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic G2 DNA damage checkpoint is shorter than in wild type during a cellular response to ionizing radiation." [PMID:9042863, PomBase:mah] synonym: "advanced mitotic G2 DNA damage checkpoint deactivation during cellular response to ionizing radiation" EXACT [PomBase:mah] synonym: "decreased duration of mitotic G2 DNA damage checkpoint during cellular response to IR" EXACT [PomBase:mah] is_a: FYPO:0003489 ! abnormal mitotic cell cycle regulation during cellular response to ionizing radiation is_a: FYPO:0004870 ! decreased duration of mitotic G2 DNA damage checkpoint created_by: midori creation_date: 2020-02-17T11:26:22Z [Term] id: FYPO:0007249 name: normal level of X-shaped replication intermediates def: "A cell phenotype in which the level of X-shaped DNA replication intermediates is normal (i.e. indistinguishable from wild type). X-shaped intermediates may be formed by replication forks moving bidirectionally from outside the region, or by the increased formation or persistence of Holliday junctions or similar recombination intermediates." [PMID:23071723, PomBase:mah] synonym: "normal level of X-shaped DNA replication intermediates" EXACT [PomBase:mah] synonym: "normal level of X-shaped replication intermediates during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of X-shaped replication intermediates during vegetative growth" EXACT [PomBase:mah] synonym: "normal proportion of X-shaped replication intermediates" RELATED [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2020-02-17T15:20:57Z [Term] id: FYPO:0007250 name: abnormal lipid binding def: "A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can be used for any interaction with a sterol that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2020-02-28T12:16:26Z [Term] id: FYPO:0007251 name: decreased lipid binding def: "A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds heme less than wild type, or that a mutation in one gene decreases heme binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "reduced lipid binding" EXACT [PomBase:mah] is_a: FYPO:0007250 ! abnormal lipid binding created_by: midori creation_date: 2020-02-28T12:17:08Z [Term] id: FYPO:0007252 name: decreased membrane lipid binding def: "A molecular function phenotype in which occurrence of binding to a lipid in a membrane by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "decreased binding to lipid in membrane" EXACT [PomBase:mah] synonym: "reduced membrane lipid binding" EXACT [PomBase:mah] is_a: FYPO:0007251 ! decreased lipid binding created_by: midori creation_date: 2020-02-28T12:19:14Z [Term] id: FYPO:0007253 name: abolished membrane lipid binding def: "A molecular function phenotype in which binding to a lipid in a membrane by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished binding to lipid in membrane" EXACT [PomBase:mah] synonym: "membrane lipid binding abolished" EXACT [PomBase:mah] is_a: FYPO:0006937 ! abolished lipid binding created_by: midori creation_date: 2020-02-28T12:19:14Z [Term] id: FYPO:0007254 name: normal replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing is normal (i.e. indistinguishable from wild type). Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted." [GO:0031297, PomBase:mah] synonym: "normal collapsed replication fork processing" EXACT [GO:0031297] synonym: "normal HR-mediated fork restart" RELATED [PomBase:vw] synonym: "normal recovery from replication fork arrest" EXACT [GO:0031297] synonym: "normal recovery from replication fork stalling" EXACT [GO:0031297] synonym: "normal replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "normal replication fork restart" RELATED [GO:0031297] synonym: "normal replication restart" RELATED [GO:0031297] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2020-02-28T12:31:39Z [Term] id: FYPO:0007255 name: decreased replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of replication fork processing is decreased. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted." [GO:0031297, PomBase:mah] synonym: "decreased collapsed replication fork processing" EXACT [GO:0031297] synonym: "decreased HR-mediated fork restart" RELATED [PomBase:vw] synonym: "decreased recovery from replication fork arrest" EXACT [GO:0031297] synonym: "decreased recovery from replication fork stalling" EXACT [GO:0031297] synonym: "decreased replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork processing during vegetative growth" EXACT [PomBase:mah] synonym: "decreased replication fork restart" RELATED [GO:0031297] synonym: "decreased replication restart" RELATED [GO:0031297] synonym: "reduced replication fork processing" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing created_by: midori creation_date: 2020-02-28T12:36:35Z [Term] id: FYPO:0007256 name: premature protein localization to meiotic spindle pole body during prophase I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is begins earlier than normal during prophase of the first meiotic nuclear division." [PMID:22438582, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Use this term for cells in which in which the re-accumulation of some spindle pole body components does not occur at the onset of meiosis I. synonym: "advanced protein localization to meiotic spindle pole body during prophase I" EXACT [PomBase:mah] synonym: "premature protein localisation to meiotic spindle pole body during prophase I" EXACT [PomBase:mah] synonym: "premature protein localization to meiotic SPB during prophase I" EXACT [PomBase:mah] synonym: "premature protein localization to meiotic spindle pole body during prophase of first meiotic nuclear division" EXACT [PomBase:mah] synonym: "premature protein localization to spindle pole body during meiotic prophase I" EXACT [PomBase:mah] is_a: FYPO:0002771 ! abnormal protein localization to meiotic spindle pole body created_by: midori creation_date: 2020-02-28T12:41:35Z [Term] id: FYPO:0007257 name: delayed onset of protein localization to meiotic spindle pole body during meiosis I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body begins later than normal during the first meiotic nuclear division." [PMID:29259000, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. Use this term for cells in which in which the re-accumulation of some spindle pole body components does not occur at the onset of meiosis I. synonym: "delayed onset of protein localisation to meiotic spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to meiotic SPB during meiosis I" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to meiotic spindle pole body during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "delayed protein localization to meiotic spindle pole body during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0002772 ! decreased protein localization to meiotic spindle pole body created_by: midori creation_date: 2020-02-28T14:58:39Z [Term] id: FYPO:0007258 name: abnormal meiotic spindle pole body duplication def: "A cellular process phenotype in which meiotic spindle pole body duplication is abnormal." [PomBase:mah] synonym: "abnormal meiotic SPB duplication" EXACT [PomBase:mah] synonym: "abnormal spindle pole body duplication during meiotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle created_by: midori creation_date: 2020-02-28T15:17:43Z [Term] id: FYPO:0007259 name: increased meiotic spindle pole body duplication def: "A cellular process phenotype in which the occurrence of meiotic spindle pole body duplication is increased." [PMID:22438582, PomBase:mah] synonym: "increased meiotic SPB duplication" EXACT [PomBase:mah] synonym: "increased spindle pole body duplication during meiotic cell cycle" RELATED [PomBase:mah] synonym: "meiotic SPB overamplification" EXACT [PomBase:vw] is_a: FYPO:0007258 ! abnormal meiotic spindle pole body duplication created_by: midori creation_date: 2020-02-28T15:20:27Z [Term] id: FYPO:0007260 name: abnormal cellular process during meiotic cell cycle def: "A phenotype in which a specific cellular process is abnormal in the meiotic cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2020-02-28T15:23:02Z [Term] id: FYPO:0007261 name: decreased telomere tethering at nuclear periphery during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is decreased." [PomBase:mah] synonym: "decreased mitotic telomere tethering at nuclear periphery during vegetative growth" EXACT [GO:0044820] synonym: "decreased telomere anchoring at nuclear periphery during vegetative growth" EXACT [PomBase:vw] synonym: "decreased telomere tethering at nuclear periphery during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased telomere tethering to NE during vegetative growth" EXACT [PomBase:mah] synonym: "reduced telomere tethering at nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001515 ! abnormal telomere tethering at nuclear periphery during vegetative growth created_by: midori creation_date: 2020-02-28T15:37:20Z [Term] id: FYPO:0007262 name: abnormal eisosome def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, morphology, or other physical characteristic of the eisosome is abnormal. The eisosome consists of a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face." [GO:0032126, PomBase:mah] synonym: "abnormal eisosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal eisosome during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal eisosomes" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: midori creation_date: 2020-03-06T13:18:58Z [Term] id: FYPO:0007263 name: eisosomes present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer eisosomes than normal." [PomBase:mah] synonym: "decreased eisosome number" EXACT [PomBase:mah] synonym: "decreased number of eisosomes present" EXACT [PomBase:mah] synonym: "eisosomes present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "eisosomes present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "eisosomes present in reduced numbers" EXACT [PomBase:mah] synonym: "fewer eisosomes present" EXACT [PomBase:mah] is_a: FYPO:0007262 ! abnormal eisosome created_by: midori creation_date: 2020-03-06T13:40:30Z [Term] id: FYPO:0007264 name: long eisosome filament def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the eisosome filament is longer than normal." [PomBase:mah] synonym: "elongated eisosome filament" EXACT [PomBase:mah] synonym: "increased eisosome filament length" EXACT [PomBase:mah] synonym: "long eisosome filament during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long eisosome filament during vegetative growth" EXACT [PomBase:mah] synonym: "long linear eisosomes" EXACT [PomBase:al] is_a: FYPO:0007439 ! abnormal eisosome morphology created_by: midori creation_date: 2020-03-06T13:43:49Z [Term] id: FYPO:0007265 name: long eisosome filaments present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer, and longer, eisosome filaments than normal." [PMID:32023460, PomBase:mah] synonym: "decreased number of long eisosome filaments present" EXACT [PomBase:mah] synonym: "fewer long eisosome filaments present" EXACT [PomBase:mah] synonym: "long eisosome filaments present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long eisosome filaments present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "long eisosome filaments present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0007264 ! long eisosome filament relationship: has_part FYPO:0007264 ! long eisosome filament created_by: midori creation_date: 2020-03-06T13:52:00Z [Term] id: FYPO:0007266 name: decreased colocalization of cortical endoplasmic reticulum with eisosomes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum (ER) colocalizes with eisosomes to a lower extent than normal." [PMID:32023460, PomBase:mah] synonym: "decreased colocalization of cortical endoplasmic reticulum with eisosomes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased colocalization of cortical endoplasmic reticulum with eisosomes during vegetative growth" EXACT [PomBase:mah] synonym: "decreased colocalization of cortical ER with eisosomes" EXACT [PomBase:mah] synonym: "decreased colocalization of tubular cortical ER with eisosomes" EXACT [PomBase:vw] synonym: "decreased cortical ER-eisosome colocalization" EXACT [PomBase:mah] synonym: "reduced colocalization of cortical endoplasmic reticulum with eisosomes" EXACT [PomBase:mah] is_a: FYPO:0007571 ! abnormal cortical endoplasmic reticulum organization created_by: midori creation_date: 2020-03-06T14:04:15Z [Term] id: FYPO:0007267 name: increased colocalization of cortical endoplasmic reticulum with eisosomes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum (ER) colocalizes with eisosomes to a greater extent than normal." [PMID:32023460, PomBase:mah] synonym: "increased colocalization of cortical endoplasmic reticulum with eisosomes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased colocalization of cortical endoplasmic reticulum with eisosomes during vegetative growth" EXACT [PomBase:mah] synonym: "increased colocalization of cortical ER with eisosomes" EXACT [PomBase:mah] synonym: "increased colocalization of tubular cortical ER with eisosomes" EXACT [PomBase:vw] synonym: "increased cortical ER-eisosome colocalization" EXACT [PomBase:mah] is_a: FYPO:0007571 ! abnormal cortical endoplasmic reticulum organization created_by: midori creation_date: 2020-03-06T14:09:18Z [Term] id: FYPO:0007268 name: decreased cortical endoplasmic reticulum remodeling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cortical endoplasmic reticulum (ER) remodeling occurs to a lower extent than normal. Cortical ER remodeling is the dynamic spatial rearrangement of ER tubules near the cell cortex." [PMID:32023460, PomBase:mah] synonym: "decreased cortical endoplasmic reticulum remodeling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cortical endoplasmic reticulum remodeling during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cortical ER remodeling" EXACT [PomBase:mah] synonym: "reduced cortical endoplasmic reticulum remodeling" EXACT [PomBase:mah] is_a: FYPO:0007571 ! abnormal cortical endoplasmic reticulum organization created_by: midori creation_date: 2020-03-06T14:10:36Z [Term] id: FYPO:0007269 name: normal interphase mitotic telomere clustering during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering is normal (i.e. indistinguishable from wild type). Telomere clustering gathers telomeres during or prior to tethering to the nuclear periphery during interphase of the mitotic cell cycle." [GO:0120110, PomBase:mah] synonym: "normal interphase mitotic telomere clustering during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal telomere clustering during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0008381 ! chromosome region localization phenotype during vegetative growth created_by: midori creation_date: 2020-03-06T14:41:47Z [Term] id: FYPO:0007270 name: decreased Tf body tethering to centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such regions containing transposons (Tf2 elements) are tethered to the centromere to a lower extent than normal." [PMID:23084836, PomBase:mah] synonym: "decreased centromere tethering of Tf2 bodies" EXACT [PomBase:mah] synonym: "decreased Tf body tethering to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased Tf body tethering to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Tf2 body tethering to centromere" EXACT [PomBase:vw] synonym: "reduced Tf body tethering to centromere" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2020-03-06T14:51:55Z [Term] id: FYPO:0007271 name: increased Tf body tethering to centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such regions containing transposons (Tf2 elements) are tethered to the centromere to a greater extent than normal." [PMID:23084836, PomBase:mah] synonym: "increased centromere tethering of Tf2 bodies" EXACT [PomBase:mah] synonym: "increased Tf body tethering to centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased Tf body tethering to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased Tf2 body tethering to centromere" EXACT [PomBase:vw] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2020-03-06T14:56:30Z [Term] id: FYPO:0007272 name: decreased protein localization to nucleoplasm during cellular response to DNA damage def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased during a cellular response to a DNA damage stimulus." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleoplasm during cellular response to DNA damage" EXACT [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nucleoplasm during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleoplasm during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0002540 ! decreased protein localization to nucleoplasm during cellular response to hydroxyurea created_by: midori creation_date: 2020-03-06T14:58:33Z [Term] id: FYPO:0007273 name: increased cortical endoplasmic reticulum remodeling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cortical endoplasmic reticulum (ER) remodeling occurs to a greater extent than normal. Cortical ER remodeling is the dynamic spatial rearrangement of ER tubules near the cell cortex." [PMID:32023460, PomBase:mah] synonym: "increased cortical endoplasmic reticulum remodeling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cortical endoplasmic reticulum remodeling during vegetative growth" EXACT [PomBase:mah] synonym: "increased cortical ER remodeling" EXACT [PomBase:mah] is_a: FYPO:0007571 ! abnormal cortical endoplasmic reticulum organization created_by: midori creation_date: 2020-03-18T17:39:48Z [Term] id: FYPO:0007274 name: abnormal mitochondrion inheritance def: "A cellular process phenotype in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrial inheritance" EXACT [GO:0000001, PomBase:mah] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2020-03-23T13:20:42Z [Term] id: FYPO:0007275 name: abnormal mitochondrion inheritance during meiotic cell cycle def: "A cellular process phenotype in which mitochondrion inheritance is abnormal during the meiotic cell cycle. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrial inheritance during meiotic cell cycle" EXACT [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrion inheritance during meiosis" RELATED [PomBase:mah] is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle is_a: FYPO:0007274 ! abnormal mitochondrion inheritance created_by: midori creation_date: 2020-03-23T13:24:05Z [Term] id: FYPO:0007276 name: normal mitochondrion inheritance during meiotic cell cycle def: "A cellular process phenotype in which mitochondrion inheritance is normal (i.e. indistinguishable from wild type) during the meiotic cell cycle. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GO:0000001, PMID:31582398, PomBase:mah] synonym: "normal mitochondrial inheritance during meiotic cell cycle" EXACT [GO:0000001, PomBase:mah] synonym: "normal mitochondrion inheritance during meiosis" RELATED [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0007277 ! normal cellular process during meiotic cell cycle created_by: midori creation_date: 2020-03-23T13:26:48Z [Term] id: FYPO:0007277 name: normal cellular process during meiotic cell cycle def: "A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type) in the meiotic cell cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate subset: qc_do_not_manually_annotate is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2020-03-23T13:28:08Z [Term] id: FYPO:0007278 name: normal protein localization to euchromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to euchromatin is normal (i.e. indistinguishable from wild type)." [PMID:17289569, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to euchromatin" EXACT [PomBase:mah] synonym: "normal protein localization to euchromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to euchromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2020-03-23T13:36:56Z [Term] id: FYPO:0007279 name: increased protein localization to euchromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to euchromatin is increased." [PMID:17289569, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to euchromatin" EXACT [PomBase:mah] synonym: "increased protein localization to euchromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to euchromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2020-03-23T13:58:05Z [Term] id: FYPO:0007280 name: decreased protein localization to nuclear exosome focus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is decreased. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1." [PMID:32012158, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nuclear exosome focus" EXACT [PomBase:mah] synonym: "decreased protein localization to Mmi1 focus" EXACT [PomBase:mah] synonym: "decreased protein localization to Mmi1 nuclear focus complex" EXACT [GO:1990251] synonym: "decreased protein localization to nuclear exosome foci" EXACT [PomBase:mah] synonym: "decreased protein localization to nuclear exosome focus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to nuclear exosome focus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nuclear exosome focus" EXACT [PomBase:mah] is_a: FYPO:0002963 ! abnormal protein localization to nuclear exosome focus created_by: midori creation_date: 2020-03-23T14:27:16Z [Term] id: FYPO:0007281 name: normal level of meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during meiosis measured in a cell is normal (i.e. indistinguishable from wild type)." [PMID:32012158, PomBase:mah] synonym: "normal level of meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of meiotic gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal level of meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "normal level of meiotic nuclear division gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "normal meiotic gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2020-03-23T14:40:09Z [Term] id: FYPO:0007282 name: viable branched, swollen vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and branched, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "viable branched, swollen cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, swollen vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000015 ! branched vegetative cell is_a: FYPO:0002402 ! viable swollen vegetative cell with abnormal cell shape relationship: has_part FYPO:0000015 ! branched vegetative cell created_by: midori creation_date: 2020-03-23T15:13:33Z [Term] id: FYPO:0007283 name: normal protein localization to lateral cell cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the lateral cell cortex is normal (i.e. indistinguishable from wild type)." [PMID:26960792, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to lateral cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cell side during vegetative growth" RELATED [PomBase:vw] synonym: "normal protein localization to lateral cell cortex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to lateral cortex during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0001402 ! normal protein localization to cell cortex during vegetative growth created_by: midori creation_date: 2020-03-23T15:20:18Z [Term] id: FYPO:0007284 name: normal protein localization to non-growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the non-growing cell tip is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to non-growing cell tip" EXACT [PomBase:mah] synonym: "normal protein localization to non-growing cell end" EXACT [PomBase:mah] synonym: "normal protein localization to non-growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to non-growing cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: midori creation_date: 2020-03-23T15:21:59Z [Term] id: FYPO:0007285 name: abnormal dynamic protein localization to cell tip def: "A cell phenotype in which a protein that is normally dynamically localized to one or both cell tips shows an abnormal temporal pattern of localization. For example, a protein may move from one cell tip to the other at an altered frequency or amplitude." [PMID:26960792, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal dynamic protein localization to cell end" EXACT [PomBase:mah] synonym: "abnormal dynamic protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal dynamic protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal oscillatory protein localization to cell tip" NARROW [PomBase:mah] is_a: FYPO:0005987 ! abnormal protein localization to cell tip is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern created_by: midori creation_date: 2020-03-23T15:24:31Z [Term] id: FYPO:0007286 name: normal protein localization to late endosome membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the late endosome membrane is normal (i.e. indistinguishable from wild type)." [PMID:12868054, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to late endosome membrane" EXACT [PomBase:mah] synonym: "normal protein localization to late endosome membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to late endosome membrane during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to prevacuolar compartment membrane" EXACT [PomBase:vw] is_a: FYPO:0007725 ! normal protein localization to late endosome created_by: midori creation_date: 2020-03-26T13:10:38Z [Term] id: FYPO:0007287 name: decreased protein galactosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the galactosylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. Protein galactosylation is the addition of a galactose residue to a protein amino acid." [GO:0042125, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein galactosylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced protein galactosylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001910 ! abnormal protein glycosylation during vegetative growth created_by: midori creation_date: 2020-04-02T13:47:12Z [Term] id: FYPO:0007288 name: normal protein galactosylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein galactosylation is normal (i.e. indistinguishable from wild type). Protein galactosylation is the addition of a galactose residue to a protein amino acid." [GO:0042125, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein galactosylation during mitotic cell cycle" RELATED [Pombase:mah] is_a: FYPO:0000549 ! normal protein modification during vegetative growth created_by: midori creation_date: 2020-04-02T14:15:49Z [Term] id: FYPO:0007289 name: abnormal UDP-glucose 4-epimerase activity def: "A molecular function phenotype in which the observed rate of UDP-glucose 4-epimerase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2020-04-02T14:34:56Z [Term] id: FYPO:0007290 name: decreased UDP-glucose 4-epimerase activity def: "A molecular function phenotype in which the observed rate of UDP-glucose 4-epimerase activity is decreased." [PomBase:mah] synonym: "reduced UDP-glucose 4-epimerase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0007289 ! abnormal UDP-glucose 4-epimerase activity created_by: midori creation_date: 2020-04-02T14:48:30Z [Term] id: FYPO:0007291 name: decreased cellular UDP-galactose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP-galactose measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular UDP-galactose level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular UDP-galactose level during vegetative growth" EXACT [PomBase:mah] synonym: "idecreased cellular UDP-D-galactose level" EXACT [CHEBI:18307] synonym: "reduced cellular UDP-galactose level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2020-04-02T15:01:28Z [Term] id: FYPO:0007292 name: increased cytosolic UDP-galactose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP-galactose measured in the cytosol is higher than normal." [PomBase:mah] synonym: "increased cytosolic UDP-D-galactose level" EXACT [CHEBI:18307] synonym: "increased cytosolic UDP-galactose level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cytosolic UDP-galactose level during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of UDP-galactose in cytosol" EXACT [PomBase:mah] is_a: FYPO:0001948 ! increased level of substance in cytosol created_by: midori creation_date: 2012-06-18T15:09:36Z [Term] id: FYPO:0007293 name: lysed spherical vegetative cell def: "A cell phenotype in which a spherical vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost." [PMID:10087262, PomBase:mah] synonym: "inviable spherical vegetative cell with cell lysis" EXACT [PomBase:mah] is_a: FYPO:0004104 ! inviable spherical vegetative cell relationship: has_part FYPO:0000647 ! vegetative cell lysis created_by: midori creation_date: 2012-06-18T16:08:45Z [Term] id: FYPO:0007294 name: pear-shaped vegetative cell with actin localized to rounded end def: "A cell phenotype in which a vegetative cell is pear-shaped, and in which actin is localized only to the rounded end of the cell." [PMID:10087262, PomBase:mah] synonym: "pear-shaped cell with actin localized to rounded end during vegetative growth" EXACT [PomBase:mah] synonym: "pear-shaped vegetative cell with actin localized to rounded end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "pear-shaped vegetative cell with actin localized to rounded new end" NARROW [PomBase:vw] synonym: "tadpole cell" EXACT [PMID:10087262] is_a: FYPO:0001120 ! pear-shaped vegetative cell created_by: midori creation_date: 2012-06-18T16:32:36Z [Term] id: FYPO:0007295 name: increased protein localization to CENP-A containing chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to CENP-A containing chromatin" EXACT [PomBase:mah] synonym: "increased protein localization to CENP-A containing chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to CENP-A containing chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to centromeric core region chromatin" EXACT [GO:0061638] is_a: FYPO:0004311 ! abnormal protein localization to CENP-A containing chromatin created_by: midori creation_date: 2020-04-15T11:58:48Z [Term] id: FYPO:0007296 name: abolished UDP-galactose biosynthetic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of UDP-galactose does not occur." [GO:0052574, PomBase:mah] synonym: "abolished UDP-D-galactopyranose biosynthesis" EXACT [GO:0052574] synonym: "abolished UDP-D-galactose biosynthesis" EXACT [GO:0052574] synonym: "abolished UDP-galactose biosynthesis" EXACT [GO:0052574] synonym: "abolished UDP-galactose biosynthetic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished UDP-galactose biosynthetic process during vegetative growth" EXACT [PomBase:mah] synonym: "UDP-galactose biosynthetic process abolished" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2020-04-15T15:05:53Z [Term] id: FYPO:0007297 name: increased transcription from SRE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more SRE elements occurs to a greater extent than normal." [PMID:32053662, PomBase:mah] synonym: "expression of SRE target genes increased" RELATED [PomBase:mah] synonym: "increased transcription from SRE promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from SRE promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T10:00:11Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T10:00:11Z [Term] id: FYPO:0007298 name: abnormal protein aggregate center formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation is abnormal. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773, PomBase:mah] synonym: "abnormal PAC formation" EXACT [PMID:32075773] synonym: "abnormal protein aggregate center formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein aggregate center formation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein aggregate centre formation" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T10:37:45Z" xsd:dateTime creation_date: 2020-04-07T10:37:45Z [Term] id: FYPO:0007299 name: decreased protein aggregate center formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation is decreased. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773, PomBase:mah] synonym: "decreased PAC formation" EXACT [PMID:32075773] synonym: "decreased protein aggregate center formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein aggregate center formation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein aggregate centre formation" EXACT [PomBase:mah] synonym: "reduced protein aggregate center formation" EXACT [PomBase:mah] is_a: FYPO:0007298 ! abnormal protein aggregate center formation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T10:37:45Z" xsd:dateTime creation_date: 2020-04-07T10:48:54Z [Term] id: FYPO:0007300 name: abolished protein aggregate center formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation does not occur. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773, PomBase:mah] synonym: "abolished PAC formation" EXACT [PMID:32075773] synonym: "abolished protein aggregate center formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein aggregate center formation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein aggregate centre formation" EXACT [PomBase:mah] synonym: "protein aggregate center formation abolished" EXACT [PomBase:mah] is_a: FYPO:0007298 ! abnormal protein aggregate center formation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T10:37:45Z" xsd:dateTime creation_date: 2020-04-07T10:55:02Z [Term] id: FYPO:0007301 name: normal protein aggregate center formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation is normal (i.e. indistinguishable from wild type). Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773, PomBase:mah] synonym: "normal PAC formation" EXACT [PMID:32075773] synonym: "normal protein aggregate center formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein aggregate center formation during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein aggregate centre formation" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0006003 ! normal cellular component organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T10:37:45Z" xsd:dateTime creation_date: 2020-04-07T11:04:44Z [Term] id: FYPO:0007302 name: protein absent from cell during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect when the cell is subject to heat shock. Total protein or a specific protein may be affected." [PMID:32075773, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein absent from cell during heat shock during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein absent from cell during heat shock during vegetative growth" EXACT [PomBase:mah] synonym: "undetectable cellular protein level during heat shock" EXACT [PomBase:mah] is_a: FYPO:0001984 ! protein absent from cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T11:05:36Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T11:05:36Z [Term] id: FYPO:0007303 name: abnormal cell cycle arrest in mitotic metaphase with condensed chromosomes def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase under conditions where arrest does not normally occur, and in which chromosomes remain condensed." [PomBase:mah] synonym: "abnormal cell cycle arrest in metaphase of mitotic cell cycle with condensed chromosomes" EXACT [PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic metaphase with condensed chromosomes during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in metaphase with condensed chromosomes" EXACT [PomBase:mah] is_a: FYPO:0000620 ! abnormal cell cycle arrest in mitotic metaphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T11:19:01Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T11:19:01Z [Term] id: FYPO:0007304 name: short bipolar mitotic spindle during anaphase def: "A spindle phenotype in which the mitotic spindle is shorter than normal during anaphase." [PomBase:mah] synonym: "decreased mitotic spindle length during anaphase" EXACT [PomBase:mah] synonym: "short mitotic spindle during anaphase" EXACT [PomBase:vw] synonym: "short mitotic spindle during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "short mitotic spindles during anaphase" EXACT [PomBase:mah] synonym: "short spindle during mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0000732 ! short bipolar mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T11:45:37Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T11:45:37Z [Term] id: FYPO:0007305 name: increased histone H4-K5 acetylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H4K5 acetylation during vegetative growth" EXACT [GO:0043981, PomBase:mah] synonym: "increased histone H4-K5 acetylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K5 acetylation at centromere during vegetative growth" EXACT [GO:0043981, PomBase:mah] is_a: FYPO:0005309 ! increased histone H4-K5 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T12:40:28Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T12:40:28Z [Term] id: FYPO:0007306 name: increased histone H4-K12 acetylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H4K12 acetylation during vegetative growth" EXACT [GO:0043983, PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K12 acetylation at centromere during vegetative growth" EXACT [GO:0043983, PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T12:45:33Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T12:45:33Z [Term] id: FYPO:0007307 name: increased histone H3-K14 acetylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3K14 acetylation during vegetative growth" EXACT [GO:0044154, PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K14 acetylation at centromere during vegetative growth" EXACT [GO:0044154, PomBase:mah] is_a: FYPO:0000893 ! increased histone H3-K9 acetylation at centromere during vegetative growth is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T12:50:36Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T12:50:36Z [Term] id: FYPO:0007308 name: increased histone H4-K5 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K5 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K5 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K5 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K5 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K5 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4K5 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0043981, PomBase:vw] is_a: FYPO:0007305 ! increased histone H4-K5 acetylation at centromere during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T14:22:28Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T14:22:28Z [Term] id: FYPO:0007309 name: increased histone H4-K8 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K8 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K8 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K8 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K8 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K8 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4K8 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0043982, PomBase:vw] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0005308 ! increased histone H4-K8 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T14:26:26Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T14:26:26Z [Term] id: FYPO:0007310 name: increased histone H4-K12 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K12 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K12 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4K12 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0043983, PomBase:vw] is_a: FYPO:0007306 ! increased histone H4-K12 acetylation at centromere during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T14:32:42Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T14:32:42Z [Term] id: FYPO:0007311 name: increased histone H4-K16 acetylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K16 acetylation at centromere otr during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K16 acetylation at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K16 acetylation at centromeric outer repeat region during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4-K16 acetylation at pericentric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K16 acetylation at pericentromeric region during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4K16 acetylation at centromere outer repeat during vegetative growth" EXACT [GO:0043984, PomBase:vw] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T14:38:03Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T14:38:03Z [Term] id: FYPO:0007312 name: increased histone H4-K5 acetylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 at the central core of the centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K5 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K5 acetylation at centromeric central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K5 acetylation at centromere central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0005309 ! increased histone H4-K5 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T14:52:19Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T14:52:19Z [Term] id: FYPO:0007313 name: increased histone H4-K8 acetylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 at the central core of the centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K8 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K8 acetylation at centromeric central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K8 acetylation at centromere central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0005308 ! increased histone H4-K8 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T14:58:27Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T14:58:27Z [Term] id: FYPO:0007314 name: increased histone H4-K12 acetylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 at the central core of the centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K12 acetylation at centromeric central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K12 acetylation at centromere central core during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007306 ! increased histone H4-K12 acetylation at centromere during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T15:01:29Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T15:01:29Z [Term] id: FYPO:0007315 name: increased histone H4-K8 acetylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 in heterochromatin at subtelomeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K8 acetylation at subtelomere during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H4-K8 acetylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4-K8 acetylation at subtelomeric heterochromatin region during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone H4K8 acetylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased subtelomeric heterochromatin histone H4K8 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002365 ! increased histone H4 acetylation during vegetative growth is_a: FYPO:0005308 ! increased histone H4-K8 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-07T15:07:14Z" xsd:dateTime created_by: midori creation_date: 2020-04-07T15:07:14Z [Term] id: FYPO:0007316 name: altered level of macromolecular complex def: "A physical cellular phenotype in which the amount of any macromolecular complex present in a cell differs from wild type." [PomBase:mah] synonym: "abnormal level of macromolecular complex" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:00:01Z" xsd:dateTime created_by: midori creation_date: 2014-08-18T11:16:42Z [Term] id: FYPO:0007317 name: decreased cytoplasmic translation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation in the cytoplasm is decreased." [PomBase:mah] comment: Note that this term should be used only when an experiment measures protein synthesis directly, e.g. by ribosome profiling or labeled amino acid incorporation. Consider annotating to 'decreased protein level' (FYPO:0000835) or one of its descendants. synonym: "decreased cytoplasmic translation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cytoplasmic translation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cytoplasmic translation" EXACT [PomBase:mah] is_a: FYPO:0001798 ! decreased translation is_a: FYPO:0003124 ! abnormal cytoplasmic translation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:07:32Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:07:32Z [Term] id: FYPO:0007318 name: abnormal stress granule assembly def: "A cellular process phenotype in which stress granule assembly is abnormal." [PomBase:mah] synonym: "abnormal cytoplasmic stress granule assembly" EXACT [GO:0010494] synonym: "abnormal stress granule formation" EXACT [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:20:19Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:20:19Z [Term] id: FYPO:0007319 name: decreased stress granule assembly during glucose starvation def: "A cellular process phenotype in which stress granule assembly occurs to a lower extent than normal when the cell is subject to glucose starvation." [PMID:32071154, PomBase:mah] comment: Note that FYPO uses "glucose starvation" to refer specifically to conditions in which glucose is scarce enough to trigger mating, meiosis, and sporulation. For phenotypes observed in the presence of enough glucose to prevent cells from mating, use a term that specifies "during vegetative growth" plus a condition to indicate low glucose. synonym: "decreased stress granule assembly during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "decreased stress granule assembly during glucose depletion" EXACT [PomBase:vw] synonym: "decreased stress granule assembly during glucose deprivation" EXACT [PomBase:vw] synonym: "decreased stress granule assembly during glucose limitation" RELATED [PomBase:mah] synonym: "reduced stress granule assembly during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0007318 ! abnormal stress granule assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:25:33Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:25:33Z [Term] id: FYPO:0007320 name: increased stress granule assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly occurs to a greater extent than normal." [PomBase:mah] synonym: "increased cytoplasmic stress granule assembly during vegetative growth" EXACT [GO:0010494] synonym: "increased stress granule assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased stress granule formation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002347 ! abnormal stress granule assembly during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:31:53Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:31:53Z [Term] id: FYPO:0007321 name: decreased stress granule assembly during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased cytoplasmic stress granule assembly during vegetative growth" EXACT [GO:0010494] synonym: "decreased stress granule assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased stress granule formation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced stress granule assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002347 ! abnormal stress granule assembly during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:36:11Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:36:11Z [Term] id: FYPO:0007322 name: decreased stress granule assembly during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly occurs to a lower extent than normal during a cellular response to heat." [PMID:32071154, PomBase:mah] synonym: "decreased cytoplasmic stress granule assembly during cellular response to heat" EXACT [GO:0010494] synonym: "decreased stress granule assembly during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased stress granule assembly during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased stress granule assembly during cellular response to heat stress" EXACT [PomBase:mah] synonym: "decreased stress granule formation during cellular response to heat" EXACT [PomBase:mah] synonym: "reduced stress granule assembly during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0007321 ! decreased stress granule assembly during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:45:19Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:45:19Z [Term] id: FYPO:0007323 name: normal stress granule assembly during cellular response to heat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly is normal (i.e. indistinguishable from wild type) during a cellular response to heat." [PMID:32071154, PomBase:mah] synonym: "normal cytoplasmic stress granule assembly during cellular response to heat" EXACT [GO:0010494] synonym: "normal stress granule assembly during cellular response to heat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal stress granule assembly during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "normal stress granule assembly during cellular response to heat stress" EXACT [PomBase:mah] synonym: "normal stress granule formation during cellular response to heat" EXACT [PomBase:mah] is_a: FYPO:0002350 ! normal stress granule assembly during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T14:51:10Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T14:51:10Z [Term] id: FYPO:0007324 name: decreased level of histone H4 in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H4 measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased accumulation of histone H4 in cell" RELATED [PomBase:mah] synonym: "decreased cellular histone H4 level" EXACT [PomBase:mah] synonym: "decreased histone H4 level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of histone H4 in cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased level of histone H4 in cell during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of histone H4 in cell" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-04-08T16:25:47Z" xsd:dateTime created_by: midori creation_date: 2020-04-08T16:25:47Z [Term] id: FYPO:0007325 name: increased tRNA binding def: "A molecular function phenotype in which an interaction between a protein and a transfer RNA (tRNA) is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [PomBase:mah] synonym: "increased protein-transfer RNA interaction" EXACT [PomBase:mah] synonym: "increased protein-tRNA interaction" EXACT [PomBase:mah] synonym: "increased transfer RNA binding" EXACT [PomBase:mah] is_a: FYPO:0002135 ! increased protein-RNA interaction created_by: midori creation_date: 2020-04-15T15:25:12Z [Term] id: FYPO:0007326 name: decreased mitochondrial tRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial tRNA 3'-end processing is decreased. In mitochondrial tRNA 3'-end processing, the 3' end of a mitochondrial pre-tRNA molecule is converted to that of a mature mitochondrial tRNA." [GO:0006396, PomBase:mah] synonym: "decreased mitochondrial transfer RNA 3'-end processing" EXACT [PomBase:mah] synonym: "decreased mitochondrial tRNA 3'-end processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial tRNA 3'-end processing during vegetative growth" EXACT [PomBase:mah] synonym: "reduced mitochondrial tRNA 3'-end processing" EXACT [PomBase:mah] is_a: FYPO:0004956 ! abnormal mitochondrial RNA 3'-end processing created_by: midori creation_date: 2020-04-15T15:28:53Z [Term] id: FYPO:0007327 name: DNA content decreased during G0 def: "A cell phenotype which the total amount of DNA in a cell is lower than normal when the cell is in G0 phase." [PomBase:mah] synonym: "decreased DNA content during cell quiescence" EXACT [PomBase:mah] synonym: "decreased DNA level during G0" EXACT [PomBase:mah] synonym: "DNA content decreased during quiescence" EXACT [PomBase:mah] synonym: "DNA content reduced during G0" EXACT [PomBase:mah] is_a: FYPO:0004320 ! altered DNA level created_by: midori creation_date: 2020-04-15T16:32:13Z [Term] id: FYPO:0007328 name: normal number of Rad52 foci during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type)." [PMID:31833215, PomBase:mah] synonym: "normal number of Rad22 foci" EXACT [PomBase:mah] synonym: "normal number of Rad52 foci during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth is_a: FYPO:0007723 ! normal cellular physical quality phenotype created_by: midori creation_date: 2020-04-17T15:59:38Z [Term] id: FYPO:0007329 name: increased DNA damage at tRNA genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured at transfer RNA genes in a cell is greater than normal. The number, extent, or both of damage sites may be increased." [PMID:31833215, PomBase:mah] synonym: "increased DNA damage at transfer RNA genes" EXACT [PomBase:mah] synonym: "increased DNA damage at tRNA genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased DNA damage at tRNA genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of DNA lesions at tRNA genes during vegetative growth" RELATED [PomBase:al] is_a: FYPO:0003547 ! increased DNA damage during vegetative growth created_by: midori creation_date: 2020-04-17T16:01:49Z [Term] id: FYPO:0007330 name: sensitive to formaldehyde def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to formaldehyde. Cells stop growing (and may die) at a concentration of formaldehyde that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to formaldehyde" EXACT [PomBase:mah] synonym: "sensitive to formaldehyde during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to formaldehyde during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2020-04-17T16:27:55Z [Term] id: FYPO:0007331 name: normal growth on formaldehyde def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing formaldehyde." [PomBase:mah] synonym: "normal cell population growth in presence of formaldehyde" EXACT [PomBase:mah] synonym: "normal cell population growth on formaldehyde" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on formaldehyde" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2020-04-17T16:29:25Z [Term] id: FYPO:0007332 name: abolished increase in protein phosphorylation during cellular response to stress in presence of small molecule def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an increase in the phosphorylation of one or more specific proteins that would normally occur when cells are subjected to a stress in the presence of a specific small molecule does not occur under the same circumstances." [PMID:31932483, PomBase:mah] comment: Use this term when a difference between wild type and a mutant is seen only when both the stress and the small molecule are present. An example is protein phosphorylation under oxidative stress in the presence of the small molecule INR119. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished increase in protein phosphorylation by small molecule" RELATED [PMID:31932483] synonym: "abolished increase in protein phosphorylation during cellular response to stress in presence of small molecule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished increase in protein phosphorylation during cellular response to stress in presence of small molecule during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002033 ! abolished protein phosphorylation during vegetative growth created_by: midori creation_date: 2020-04-17T16:44:48Z [Term] id: FYPO:0007333 name: abolished chromatin silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core)." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abolished chromatin silencing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "chromatin silencing abolished" EXACT [PomBase:mah] synonym: "chromatin silencing abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000575 ! abolished gene silencing created_by: midori creation_date: 2020-04-21T13:38:04Z [Term] id: FYPO:0007334 name: abolished chromatin silencing at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at centromere outer repeat regions." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abolished chromatin silencing at centromere otr" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at centromere outer repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished chromatin silencing at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at centromeric outer repeat region" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at pericentric region" RELATED [PomBase:mah] synonym: "abolished chromatin silencing at pericentromeric region" RELATED [PomBase:mah] synonym: "abolished heterochromatin silencing at centromere outer repeat region" EXACT [PomBase:mah] synonym: "chromatin silencing at centromere outer repeat abolished" EXACT [PomBase:mah] is_a: FYPO:0002346 ! abnormal chromatin silencing at centromere outer repeat is_a: FYPO:0007333 ! abolished chromatin silencing created_by: midori creation_date: 2020-04-21T13:39:54Z [Term] id: FYPO:0007335 name: abolished chromatin silencing at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at centromere inner repeat regions." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abolished chromatin silencing at centromere imr" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at centromere inner repeat during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished chromatin silencing at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at centromeric inner repeat region" EXACT [PomBase:mah] synonym: "abolished heterochromatin silencing at centromere inner repeat" EXACT [PomBase:mah] synonym: "chromatin silencing at centromere inner repeatabolished" EXACT [PomBase:mah] is_a: FYPO:0000146 ! abnormal chromatin silencing at centromere is_a: FYPO:0007333 ! abolished chromatin silencing created_by: midori creation_date: 2020-04-21T13:42:14Z [Term] id: FYPO:0007336 name: abolished chromatin silencing at silent mating-type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at the silent mating-type cassettes." [PomBase:mah] comment: Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin. See the GO cellular component term 'heterochromatin' (GO:0000792), and the biological process term 'heterochromatin organization' (GO:0070828). synonym: "abolished chromatin silencing at mating-type region heterochromatin" EXACT [PomBase:mah] synonym: "abolished chromatin silencing at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished chromatin silencing at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "chromatin silencing at silent mating-type cassette abolished" EXACT [PomBase:mah] is_a: FYPO:0000156 ! abnormal chromatin silencing at silent mating-type cassette is_a: FYPO:0007333 ! abolished chromatin silencing created_by: midori creation_date: 2020-04-21T13:51:24Z [Term] id: FYPO:0007337 name: increased histone H3-K4 methylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 4 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3-K4 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3 K4 methylation at centromere" EXACT [GO:0051568, PomBase:mah] synonym: "increased histone H3-K4 methylation at centromere during mitotic cell cycle during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K4 methylation at centromeric region" EXACT [PomBase:vw] synonym: "increased histone H3K4 methylation at centromere" EXACT [PomBase:vw] synonym: "increased histone H3K4me at centromere" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 methylation at centromere" EXACT [GO:0051568, PomBase:mah] is_a: FYPO:0000869 ! increased histone methylation during vegetative growth is_a: FYPO:0002330 ! abnormal histone H3-K4 methylation during vegetative growth is_a: FYPO:0007374 ! abnormal histone methylation at centromere during vegetative growth created_by: midori creation_date: 2020-04-21T14:16:02Z [Term] id: FYPO:0007338 name: increased histone H3-K4 trimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3-K4 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3 K4 trimethylation at centromere" EXACT [PomBase:mah] synonym: "increased histone H3-K4 trimethylation at centromere during mitotic cell cycle during vegetative growth" RELATED [PomBase:mah] synonym: "increased histone H3-K4 trimethylation at centromeric region" EXACT [PomBase:vw] synonym: "increased histone H3K4 trimethylation at centromere" EXACT [PomBase:vw] synonym: "increased histone H3K4me3 at centromere" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K4 trimethylation at centromere" EXACT [PomBase:mah] is_a: FYPO:0007337 ! increased histone H3-K4 methylation at centromere during vegetative growth created_by: midori creation_date: 2020-04-21T14:19:29Z [Term] id: FYPO:0007339 name: increased cen-dg RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which of RNAs transcribed from dg repeats in the centromere outer repeat region are present at higher levels than normal." [PMID:18957202, PomBase:mah] synonym: "increased cen-dg RNA accumulation" RELATED [PomBase:mah] synonym: "increased cen-dg RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cen-dg RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cen-dg transcript level" EXACT [PomBase:mah] synonym: "increased level of cen-dg RNA" EXACT [PomBase:mah] synonym: "increased level of cen-dg transcripts" EXACT [PomBase:mah] synonym: "increased level of centromeric dg repeat RNA" EXACT [PomBase:mah] synonym: "increased level of centromeric dg repeat transcripts" EXACT [PomBase:mah] is_a: FYPO:0000220 ! increased centromeric outer repeat transcript level created_by: midori creation_date: 2020-04-21T14:27:49Z [Term] id: FYPO:0007340 name: increased spatial extent of protein localization to euchromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to a larger portion of the chromosome than normal in the euchromatic regions." [PMID:18957202, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased spatial extent of protein localisation to euchromatin" EXACT [PomBase:mah] synonym: "increased spatial extent of protein localization to euchromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased spatial extent of protein localization to euchromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007465 ! altered spatial extent of protein localization to chromatin created_by: midori creation_date: 2020-04-21T14:31:16Z [Term] id: FYPO:0007341 name: normal histone H3-K4 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K4 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K4 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K4me3 during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H3 K4 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005311 ! normal histone H3-K4 methylation during vegetative growth created_by: midori creation_date: 2020-04-21T14:35:23Z [Term] id: FYPO:0007342 name: decreased triglyceride level in lipid droplet def: "A cell phenotype in which the amount of one or more triglycerides measured in lipid droplets is lower than normal." [PomBase:mah] synonym: "decreased lipid droplet triglyceride level" EXACT [PomBase:mah] synonym: "decreased TAG level in lipid droplet" EXACT [PomBase:mah] synonym: "decreased triacylglycerol level in lipid droplet" EXACT [PomBase:mah] synonym: "decreased triglyceride accumulation in lipid droplet" RELATED [PomBase:mah] synonym: "reduced cellular triglyceride level in lipid droplet" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth created_by: midori creation_date: 2020-04-21T14:58:26Z [Term] id: FYPO:0007343 name: abolished lipid droplet formation def: "A cellular process phenotype in which the occurrence of lipid droplet formation does not occur." [PomBase:mah] synonym: "abolished lipid droplet assembly" EXACT [PomBase:mah] synonym: "abolished lipid particle formation" EXACT [PomBase:mah] synonym: "lipid droplet formation abolished" EXACT [PomBase:mah] is_a: FYPO:0008430 ! abnormal lipid droplet formation created_by: midori creation_date: 2020-04-21T15:02:35Z [Term] id: FYPO:0007344 name: increased protein localization to chromatin at the centromere central core during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at centromere central core during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromosome, centric central core" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centromeric central core during vegetative growth" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000451 ! increased protein localization to centromere during vegetative growth is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth created_by: midori creation_date: 2020-04-21T15:06:46Z [Term] id: FYPO:0007345 name: increased euchromatin-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from euchromatic regions measured in a cell is higher than normal." [PMID:18957202, PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased accumulation of euchromatin-derived RNAs" RELATED [PomBase:vw] synonym: "increased euchromatin-derived RNA accumulation" RELATED [PomBase:mah] synonym: "increased euchromatin-derived RNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased euchromatin-derived RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased euchromatin-derived transcript level" EXACT [PomBase:mah] synonym: "increased level of RNA transcribed from euchromatin" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2020-04-21T15:41:10Z [Term] id: FYPO:0007346 name: normal growth during cellular response to DNA damage def: "A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to DNA damage." [PomBase:mah] comment: Use this term if you have assayed growth of cells exposed to DNA damage in culture. If you have assayed the response to DNA damage at the subcellular or molecular level, consider annotating to a more specific term (e.g. normal protein phosphorylation during cellular response to DNA damage FYPO:0002899). Also consider specific phenotype terms for growth upon exposure to substances or other stimuli that can damage DNA, e.g. 'normal growth on methyl methanesulfonate' (FYPO:0000957), 'normal growth during cellular response to UV' (FYPO:0000969), etc. synonym: "normal cell population growth during cellular response to DNA damage" EXACT [PomBase:mah] synonym: "normal cellular response to DNA damage" RELATED [PomBase:mah] synonym: "normal sensitivity to DNA damage" RELATED [PomBase:vw] synonym: "normal vegetative cell population growth during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2020-04-22T14:43:28Z [Term] id: FYPO:0007347 name: normal histone H3-K36 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K36 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K36me3 during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone lysine H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation during vegetative growth created_by: midori creation_date: 2020-04-30T13:11:58Z [Term] id: FYPO:0007348 name: decreased histone H3-K36 trimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is decreased." [PomBase:mah] synonym: "decreased histone H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K36 trimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K36me3 during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K36 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K36 trimethylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002918 ! abnormal histone H3-K36 methylation during vegetative growth created_by: midori creation_date: 2020-04-30T13:14:13Z [Term] id: FYPO:0007349 name: decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 1 def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region on chromosome 1." [PMID:31811152, PomBase:mah, PomBase:vw] synonym: "decreased homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region on chromosome 1" EXACT [GO:0007129] synonym: "decreased homologous chromosome pairing at omt3 locus" NARROW [PomBase:vw] synonym: "decreased synapsis at cis-acting homologous chromosome pairing region on chromosome 1" EXACT [GO:0007129] synonym: "reduced homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 1" EXACT [PomBase:mah] is_a: FYPO:0003054 ! decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2020-04-30T14:27:07Z [Term] id: FYPO:0007350 name: decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 2 def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region on chromosome 2." [PMID:31811152, PomBase:mah, PomBase:vw] synonym: "decreased homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region on chromosome 2" EXACT [GO:0007129] synonym: "decreased homologous chromosome pairing at sme2 locus" NARROW [PomBase:vw] synonym: "decreased synapsis at cis-acting homologous chromosome pairing region on chromosome 2" EXACT [GO:0007129] synonym: "reduced homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 2" EXACT [PomBase:mah] is_a: FYPO:0003054 ! decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2020-04-30T14:31:10Z [Term] id: FYPO:0007351 name: decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 3 def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region on chromosome 3." [PMID:31811152, PomBase:mah, PomBase:vw] synonym: "decreased homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region on chromosome 3" EXACT [GO:0007129] synonym: "decreased homologous chromosome pairing at RNA584 locus" NARROW [PomBase:vw] synonym: "decreased synapsis at cis-acting homologous chromosome pairing region on chromosome 3" EXACT [GO:0007129] synonym: "reduced homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 3" EXACT [PomBase:mah] is_a: FYPO:0003054 ! decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2020-04-30T14:31:41Z [Term] id: FYPO:0007352 name: normal homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 1 def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region on chromosome 1." [PMID:31811152, PomBase:mah, PomBase:vw] synonym: "normal homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region on chromosome 1" EXACT [GO:0007129] synonym: "normal homologous chromosome pairing at omt3 locus" NARROW [PomBase:vw] synonym: "normal synapsis at cis-acting homologous chromosome pairing region on chromosome 1" EXACT [GO:0007129] is_a: FYPO:0003051 ! normal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2020-04-30T14:32:31Z [Term] id: FYPO:0007353 name: normal homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 2 def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region on chromosome 2." [PMID:31811152, PomBase:mah, PomBase:vw] synonym: "normal homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region on chromosome 2" EXACT [GO:0007129] synonym: "normal homologous chromosome pairing at sme2 locus" NARROW [PomBase:vw] synonym: "normal synapsis at cis-acting homologous chromosome pairing region on chromosome 2" EXACT [GO:0007129] is_a: FYPO:0003051 ! normal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2020-04-30T14:34:30Z [Term] id: FYPO:0007354 name: normal homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 3 def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region on chromosome 3." [PMID:31811152, PomBase:mah, PomBase:vw] synonym: "normal homologous chromosome pairing at meiosis at cis-acting homologous chromosome pairing region on chromosome 3" EXACT [GO:0007129] synonym: "normal homologous chromosome pairing at RNA584 locus" NARROW [PomBase:vw] synonym: "normal synapsis at cis-acting homologous chromosome pairing region on chromosome 3" EXACT [GO:0007129] is_a: FYPO:0003051 ! normal homologous chromosome pairing at cis-acting homologous chromosome pairing region created_by: midori creation_date: 2020-04-30T14:35:00Z [Term] id: FYPO:0007355 name: increased number of Smp foci def: "A cell phenotype in which the cell contains more Smp foci than normal." [PMID:31811152, PomBase:mah] synonym: "increased number of Sme2 foci" NARROW [PomBase:vw] synonym: "increased number of Smp dots" EXACT [GO:0062238] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: midori creation_date: 2020-04-30T15:25:33Z [Term] id: FYPO:0007356 name: normal Smp focus formation def: "A cellular process phenotype in which Smp focus formation is normal (i.e. indistinguishable from wild type)." [PMID:31811152, PomBase:mah] synonym: "normal Sme2 focus formation" NARROW [GO:0062238] synonym: "normal Smp dot formation" EXACT [GO:0062238] synonym: "normal Smp focus assembly" EXACT [PomBase:mah] is_a: FYPO:0006839 ! normal protein-containing complex assembly created_by: midori creation_date: 2020-04-30T15:26:19Z [Term] id: FYPO:0007357 name: Smp focus absent from cell def: "A cell phenotype in which the cell does not contain a detectable Smp focus." [PMID:31811152, PomBase:mah] synonym: "absence of Smp focus" EXACT [PomBase:vw] synonym: "absent Smp focus" EXACT [PomBase:mah] synonym: "Sme2 focus absent from cell" NARROW [PomBase:vw] synonym: "Smp dot complex absent from cell" EXACT [GO:0062238] synonym: "Smp focus absent from cell during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component is_a: FYPO:0007316 ! altered level of macromolecular complex created_by: midori creation_date: 2020-04-30T15:26:33Z [Term] id: FYPO:0007358 name: sensitive to heavy water def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to heavy water (D2O). Cells stop growing (and may die) at a concentration of heavy water that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to heavy water" EXACT [PomBase:mah] synonym: "sensitive to D2O" EXACT [PomBase:mah] synonym: "sensitive to dideuterium oxide" EXACT [CHEBI:41981] synonym: "sensitive to heavy water during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to heavy water during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: midori creation_date: 2020-04-30T15:44:30Z [Term] id: FYPO:0007359 name: resistance to heavy water def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of heavy water (D2O) than normal." [PomBase:mah] synonym: "resistance to D2O" EXACT [PomBase:mah] synonym: "resistance to dideuterium oxide" EXACT [CHEBI:41981] synonym: "resistance to heavy water during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to heavy water during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to heavy water" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2020-04-30T15:47:11Z [Term] id: FYPO:0007360 name: decreased positive regulation of ATPase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of an ATPase activity occurs to a lower extent than normal." [PMID:32204793, PomBase:mah] synonym: "decreased activation of ATPase activity" NARROW [GO:0032781] synonym: "decreased positive regulation of ATPase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased positive regulation of ATPase activity during vegetative growth" EXACT [PomBase:mah] synonym: "reduced positive regulation of ATPase activity" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2020-04-30T15:58:43Z [Term] id: FYPO:0007361 name: abolished positive regulation of ATPase activity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of an ATPase activity does not occur." [PMID:32204793, PomBase:mah] synonym: "abolished activation of ATPase activity" NARROW [GO:0032781] synonym: "abolished positive regulation of ATPase activity during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished positive regulation of ATPase activity during vegetative growth" EXACT [PomBase:mah] synonym: "positive regulation of ATPase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: midori creation_date: 2020-04-30T15:59:13Z [Term] id: FYPO:0007362 name: abolished double-stranded DNA bridging def: "A molecular function phenotype in which DNA binding that bridges two double-stranded DNA regions does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:30626735, PomBase:mah] synonym: "abolished dsDNA bridging" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2020-05-04T15:17:34Z [Term] id: FYPO:0007363 name: abnormal pyruvate kinase activity def: "A molecular function phenotype in which the observed rate of pyruvate kinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2020-05-06T15:22:25Z [Term] id: FYPO:0007364 name: increased pyruvate kinase activity def: "A molecular function phenotype in which the observed rate of pyruvate kinase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0007363 ! abnormal pyruvate kinase activity created_by: midori creation_date: 2020-05-06T15:22:29Z [Term] id: FYPO:0007365 name: decreased cellular phosphoenolpyruvate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphoenolpyruvate measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular PEP level" EXACT [PomBase:mah] synonym: "decreased cellular phosphoenolpyruvate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular phosphoenolpyruvate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of phosphoenolpyruvate in cell" EXACT [PomBase:mah] synonym: "reduced cellular phosphoenolpyruvate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2020-05-06T15:25:36Z [Term] id: FYPO:0007366 name: decreased cellular 2,3-bisphosphoglyceric acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2,3-bisphosphoglyceric acid measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular 2,3-bisphosphoglycerate level" RELATED [PomBase:mah] synonym: "decreased cellular 2,3-bisphosphoglyceric acid level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cellular 2,3-bisphosphoglyceric acid level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular 2-/3-bisphosphoglyceric acid level" EXACT [PMID:32319721] synonym: "decreased level of 2,3-bisphosphoglyceric acid in cell" EXACT [PomBase:mah] synonym: "reduced cellular 2,3-bisphosphoglyceric acid level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2020-05-06T15:26:47Z [Term] id: FYPO:0007367 name: increased cellular fructose 1,6-bisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of fructose 1,6-bisphosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular D-fructose 1,6-bisphosphate level" EXACT [CHEBI:78682] synonym: "increased cellular fructose 1,6-bisphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular fructose 1,6-bisphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased fructose 1,6-bisphosphate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2020-05-06T15:29:39Z [Term] id: FYPO:0007368 name: increased energy charge def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell's energy charge higher than normal. Energy charge is a measure of energy available to the cell, as reflected in the ATP-ADP-AMP balance and defined as (ATP + 1/2 ADP)/(AMP + ADP + ATP)." [PMID:32319721, PMID:6027798, PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2020-05-06T15:36:42Z [Term] id: FYPO:0007369 name: altered cellular redox status def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell's redox status differs from normal, as measured by the ratios of reduced to oxidized forms of one or more metabolites (e.g. NAD+:NADH)." [PMID:32319721, PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype created_by: midori creation_date: 2020-05-06T15:38:29Z [Term] id: FYPO:0007370 name: increased cell population growth rate on fructose carbon source def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing fructose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced growth on fructose" RELATED [PomBase:mah] synonym: "fast cell population growth on fructose carbon source" EXACT [PomBase:mah] synonym: "increased cell population proliferation on fructose carbon source" RELATED [PomBase:vw] synonym: "increased cell proliferation on fructose carbon source" RELATED [PomBase:vw] synonym: "increased vegetative cell population growth rate on fructose carbon source" EXACT [PomBase:mah] is_a: FYPO:0000636 ! increased cell population growth rate is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: midori creation_date: 2020-05-06T15:40:14Z [Term] id: FYPO:0007371 name: increased cell population growth rate on sucrose carbon source def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing sucrose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced growth on sucrose" RELATED [PomBase:mah] synonym: "fast cell population growth on sucrose carbon source" EXACT [PomBase:mah] synonym: "increased cell population proliferation on sucrose carbon source" RELATED [PomBase:vw] synonym: "increased cell proliferation on sucrose carbon source" RELATED [PomBase:vw] synonym: "increased vegetative cell population growth rate on sucrose carbon source" EXACT [PomBase:mah] is_a: FYPO:0000636 ! increased cell population growth rate is_a: FYPO:0009076 ! increased cell population growth on sucrose carbon source created_by: midori creation_date: 2020-05-06T15:41:15Z [Term] id: FYPO:0007372 name: resistance to chlorpromazine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of chlorpromazine than normal." [PomBase:mah] synonym: "resistance to chlorpromazine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to chlorpromazine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to chlorpromazine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2020-05-06T15:42:29Z [Term] id: FYPO:0007373 name: abnormal histone methylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in silent mating-type cassettes is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered." [PomBase:mah] synonym: "abnormal histone methylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone methylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2020-05-12T13:29:47Z [Term] id: FYPO:0007374 name: abnormal histone methylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in centromeric regions is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered." [PomBase:mah] synonym: "abnormal centromeric histone methylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone methylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2020-05-12T13:42:20Z [Term] id: FYPO:0007375 name: abnormal histone methylation at telomere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in telomeric regions is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered." [PomBase:mah] synonym: "abnormal histone methylation at telomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal telomeric histone methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation during vegetative growth created_by: midori creation_date: 2020-05-12T13:43:33Z [Term] id: FYPO:0007376 name: abolished epigenetic heterochromatin inheritance def: "A phenotype in which a region of the genome that is normally stably assembled and maintained as heterochromatin over successive generations entirely loses heterochromatic structure." [PMID:29899117, PMID:31278118, PomBase:mah] synonym: "abolished epigenetic heterochromatin propagation" EXACT [PomBase:mah] synonym: "abolished epigenetic inheritance of heterochromatin" EXACT [PomBase:mah] synonym: "abolished PEV" RELATED [PMID:31278118] is_a: FYPO:0007477 ! abnormal epigenetic heterochromatin inheritance created_by: midori creation_date: 2020-05-12T13:57:00Z [Term] id: FYPO:0007377 name: protein mislocalized to medial cortex during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the medial cortex is observed there during interphase of the mitotic cell cycle." [PMID:9679144, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to medial cortex during mitotic interphase" EXACT [PomBase:mah] synonym: "protein mislocalised to medial cortex during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to medial cortex during interphase of mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003390 ! protein mislocalized to medial cortex during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-05-19T12:21:18Z" xsd:dateTime [Term] id: FYPO:0007378 name: normal spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which rapid, back-and-forth movement of the mitotic spindle pole body (SPB), and associated chromosome movement, is normal (i.e. indistinguishable from wild type). SPB oscillation occurs during mitotic interphase (as well as prophase) and is restricted to a small space." [GO:0140405, PMID:18495844, PomBase:mah] synonym: "normal mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "normal mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "normal spindle pole body-led chromosome movement during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-05-27T10:33:22Z" xsd:dateTime [Term] id: FYPO:0007379 name: T-shaped vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T." [PomBase:mah, PomBase:vw] comment: One distinction between T-shaped and other branched cells is that in T-shaped cells the new growth zone forms before NETO. A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "T-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "T-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000015 ! branched vegetative cell is_a: FYPO:0002197 ! viable vegetative cell with abnormal cell shape is_a: FYPO:0005566 ! T-shaped cell relationship: output_of FYPO:0000026 ! abnormal vegetative cell polarity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-05-27T11:17:42Z" xsd:dateTime [Term] id: FYPO:0007380 name: elongated T-shaped vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer than normal, and a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T." [PomBase:mah, PomBase:vw] comment: One distinction between T-shaped and other branched cells is that in T-shaped cells the new growth zone forms before NETO. A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. synonym: "elongated T-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated T-shaped vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "long T-shaped vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0007379 ! T-shaped vegetative cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-05-27T11:24:32Z" xsd:dateTime [Term] id: FYPO:0007381 name: Ssb1 megafocus present def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the protein Ssb1 accumulates in a large focus, or occasionally two foci, in the nucleus." [PMID:26246602, PMID:32341083, PomBase:mah] synonym: "RPA megafocus present" EXACT [PMID:32341083, PomBase:mah] synonym: "single enlarged Ssb1 focus present" RELATED [PomBase:mah] synonym: "Ssb1 megafocus present during mitotic cell cycle" RELATED [PomBase:mah] synonym: "Ssb1 megafocus present during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-05-27T12:58:23Z" xsd:dateTime [Term] id: FYPO:0007382 name: normal transcription regulatory region sequence-specific DNA binding def: "A molecular function phenotype in which occurrence of DNA binding at a transcription regulatory region by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal promoter binding" RELATED [PomBase:mah] synonym: "normal sequence-specific DNA binding at transcription regulatory region" EXACT [PomBase:mah] synonym: "normal transcription regulatory region binding" EXACT [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-02T12:42:17Z" xsd:dateTime [Term] id: FYPO:0007383 name: abolished protein localization to kinetochore during mitotic spindle assembly checkpoint signaling def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome does not occur during mitotic spindle assembly checkpoint signaling." [PMID:22825872, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during mitotic spindle assembly checkpoint signalling" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during mitotic cell cycle spindle assembly checkpoint signaling" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during signal transduction involved in mitotic spindle assembly checkpoint" EXACT [GO:0072480] synonym: "abolished protein localization to kinetochore during spindle assembly checkpoint signaling during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein recruitment to unattached kinetochores" EXACT [PomBase:vw] synonym: "protein localization to kinetochore during mitotic spindle assembly checkpoint signaling abolished" EXACT [PomBase:mah] is_a: FYPO:0001269 ! abolished protein localization to kinetochore during vegetative growth is_a: FYPO:0008164 ! abnormal protein localization to kinetochore during mitotic M phase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-02T13:08:19Z" xsd:dateTime [Term] id: FYPO:0007384 name: normal protein distribution along RNA polymerase II-transcribed genes during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type) during a cellular response to oxidative stress." [PMID:28652406, PomBase:mah] comment: Usually assayed for RNA polymerase, transcription factors, or other components of the transcription machinery. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein distribution across RNA polymerase II-transcribed genes during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-regulated genes during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-transcribed genes during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-transcribed genes during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein distribution in chromatin along RNA polymerase II-transcribed genes during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin along RNA polymerase II-transcribed genes during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0006021 ! normal protein distribution along RNA polymerase II-transcribed genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-09T12:38:25Z" xsd:dateTime [Term] id: FYPO:0007385 name: increased duration of protein-protein interaction def: "A molecular function phenotype in which the binding of one protein to another occurs for a longer time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PMID:28366743, PomBase:mah] synonym: "increased duration of protein binding" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein-protein interaction property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-09T13:02:15Z" xsd:dateTime [Term] id: FYPO:0007386 name: decreased histone H2B-K119 ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B occurs to a lower extent than normal. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PomBase:mah] synonym: "decreased histone H2B conserved C-terminal lysine ubiquitination during vegetative growth" EXACT [GO:0071894] synonym: "decreased histone H2B-K119 ubiquitination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "reduced histone H2B-K119 ubiquitination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005607 ! abnormal histone H2B-K119 ubiquitination during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-09T13:19:26Z" xsd:dateTime [Term] id: FYPO:0007387 name: abolished NETO, with growth from new end def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) does not occur, and the cell grows only from the new end." [PMID:12007420, PomBase:mah] synonym: "abolished cell growth mode switching, monopolar to bipolar, with growth from new end" EXACT [GO:0051523] synonym: "abolished NETO during vegetative growth, with growth from new end" EXACT [PomBase:mah] synonym: "abolished NETO, with cell growth from new end" EXACT [PomBase:mah] synonym: "abolished NETO, with growth from new end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished NETO, with growth from new end during vegetative growth" EXACT [PomBase:mah] synonym: "abolished NETO, with monopolar growth from new end" EXACT [PomBase:mah] synonym: "abolished new end take-off, with growth from new end" EXACT [PomBase:mah] synonym: "abolished switch from monopolar to bipolar cell growth, with cell growth from new end" EXACT [PomBase:mah] synonym: "abolished switch from monopolar to bipolar cell growth, with growth from new end" EXACT [PomBase:mah] synonym: "NETO abolished, with growth from new end" EXACT [PomBase:mah] is_a: FYPO:0001018 ! abolished NETO property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-11T14:49:48Z" xsd:dateTime [Term] id: FYPO:0007388 name: misoriented mitotic spindle def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle is assembled in an incorrect orientation. Normally, the spindle is parallel to the long axis of the cell." [PMID:18495844, PomBase:mah] synonym: "abnormal angle of mitotic spindle orientation" RELATED [PomBase:vw] synonym: "abnormal mitotic spindle orientation" EXACT [PomBase:mah] synonym: "misoriented mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "misoriented mitotic spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T10:14:54Z" xsd:dateTime [Term] id: FYPO:0007389 name: abnormal angle of spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body (SPB)-led chromosome movement in mitotic interphase takes place at an abnormal angle relative to the long axis of the cell. Normally, the SPB oscillation angle remains nearly parallel to the long axis." [PMID:18495844, PomBase:mah] synonym: "abnormal angle of mitotic SPB oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal angle of mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal angle of mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal angle of SPB-led chromosome movement during mitotic interphase" EXACT [PomBase:mah] synonym: "abnormal angle of spindle pole body-led chromosome movement during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal angle of spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased angle of spindle pole body-led chromosome movement during mitotic interphase" NARROW [PomBase:mah] synonym: "increased trajectory angle of SPB oscillation" RELATED [PomBase:vw] synonym: "spindle pole body-led chromosome movement during mitotic interphase at abnormal angle" EXACT [PomBase:mah] is_a: FYPO:0005348 ! abnormal spindle pole body-led chromosome movement during mitotic interphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T10:41:23Z" xsd:dateTime [Term] id: FYPO:0007390 name: increased variability of angle of spindle pole body-led chromosome movement during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body (SPB)-led chromosome movement in mitotic interphase takes place at an angle that varies more than normal. Normally, the SPB oscillation angle remains nearly parallel to the long axis of the cell." [PMID:18495844, PomBase:mah] synonym: "increased variability of angle of mitotic SPB oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "increased variability of angle of mitotic spindle pole body movement during mitotic interphase" EXACT [PomBase:mah] synonym: "increased variability of angle of mitotic spindle pole body oscillation during mitotic interphase" EXACT [PomBase:mah] synonym: "increased variability of angle of SPB-led chromosome movement during mitotic interphase" EXACT [PomBase:mah] synonym: "increased variability of angle of spindle pole body-led chromosome movement during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased variability of angle of spindle pole body-led chromosome movement during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "variable trajectory angle of SPB oscillation" RELATED [PomBase:vw] is_a: FYPO:0005348 ! abnormal spindle pole body-led chromosome movement during mitotic interphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T10:56:52Z" xsd:dateTime [Term] id: FYPO:0007391 name: inviable aneuploid spore def: "A viability phenotype in which an aneuploid spore is unable to survive under conditions in which wild type spores survive. An inviable spore does not germinate." [PMID:22737087, PomBase:mah] comment: Thes phenotype can be observed after a polyploid meiosis, where aneuploid spores no longer form small colonies. This results in an increase of large to small colonies and decreased spore viability. synonym: "abolished aneuploid spore germination" EXACT [PomBase:mah] synonym: "aneuploid spore germination abolished" EXACT [PomBase:mah] synonym: "decreased aneuploid spore viability" EXACT [PomBase:mah] synonym: "decreased viability of aneuploid cells" RELATED [PomBase:jh, PomBase:vw] synonym: "decreased viability of aneuploid spores" RELATED [PomBase:jh, PomBase:vw] synonym: "lethal in aneuploid spore" RELATED [PomBase:jh, PomBase:vw] is_a: FYPO:0002151 ! inviable spore property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T13:11:21Z" xsd:dateTime [Term] id: FYPO:0007392 name: increased loss of disomic chromosome 3 def: "A cell phenotype in which that are aneuploid due to the presence of an extra copy of chromosome 3 lose the extra chromosome, producing haploid daughter cells, at a higher frequency than in otherwise wild-type cells." [PMID:22737087, PomBase:jh, PomBase:mah] comment: This phenotype results from increased chromosome instability in aneuploid cells, restores the cells to euhaploid, and causes haploid colonies to arise at a higher frequency. synonym: "increased haploidisation in presence of chromosome 3 disomy" RELATED [PomBase:jh, PomBase:vw] synonym: "increased loss of disomic chromosome 3 during mitotic cell cycle" RELATED [PomBase:jh, PomBase:vw] synonym: "increased loss of disomic chromosome 3 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T13:21:50Z" xsd:dateTime [Term] id: FYPO:0007393 name: septum mislocalized to cell tip def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum with both ends at the cell tip(s). The normal location is at the midpoint of the long axis of the cell." [PMID:32101481, PomBase:mah, PomBase:vw] comment: Includes cells where both ends of the septum are found at the same end of the cell, and cells where one end of the septum is found at each end. synonym: "septum mislocalized to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septum mislocalized to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "tip septation" EXACT [PMID:32101481] is_a: FYPO:0003210 ! mislocalized, misoriented septum property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T13:46:52Z" xsd:dateTime [Term] id: FYPO:0007394 name: abnormal RNA structure def: "A phenotype in which the structure of one or more RNA molecules differs from normal." [PMID:24793650, PomBase:mah] synonym: "abnormal RNA secondary structure" NARROW [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T14:08:56Z" xsd:dateTime [Term] id: FYPO:0007395 name: abnormal heme import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell is abnormal." [GO:0140420, PomBase:mah] synonym: "abnormal haem import" EXACT [PomBase:mah] synonym: "abnormal heme import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal heme import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal heme import into cell" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T15:06:49Z" xsd:dateTime [Term] id: FYPO:0007396 name: decreased heme import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell occurs to a lower extent than normal." [GO:0140420, PomBase:mah] synonym: "decreased haem import" EXACT [PomBase:mah] synonym: "decreased heme import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased heme import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased heme import into cell" EXACT [PomBase:mah] synonym: "reduced heme import" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T15:13:02Z" xsd:dateTime [Term] id: FYPO:0007397 name: abolished heme import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell is abolished." [GO:0140420, PomBase:mah] synonym: "abolished haem import" EXACT [PomBase:mah] synonym: "abolished heme import during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished heme import during vegetative growth" EXACT [PomBase:mah] synonym: "abolished heme import into cell" EXACT [PomBase:mah] synonym: "heme import abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-15T15:15:30Z" xsd:dateTime [Term] id: FYPO:0007398 name: normal stress-activated MAPK cascade def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which signaling via a MAP kinase cascade that is activated in response to stress is normal (i.e. indistinguishable from wild type)." [GO:0051403, PomBase:mah] synonym: "normal MAPK signalling in response to stress" EXACT [PomBase:vw] synonym: "normal stress-activated MAPK cascade during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal stress-activated MAPK cascade during vegetative growth" EXACT [PomBase:mah] synonym: "normal stress-activated MAPK signaling pathway" EXACT [GO:0051403] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-16T10:58:20Z" xsd:dateTime [Term] id: FYPO:0007399 name: normal protein localization to kinetochore during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during interphase of mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002901 ! normal protein localization to kinetochore during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T13:22:26Z" xsd:dateTime [Term] id: FYPO:0007400 name: abolished protein localization to kinetochore during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome does not occur during interphase of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during interphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein localization to kinetochore abolished during interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007174 ! abnormal protein localization to kinetochore during mitotic interphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T13:29:26Z" xsd:dateTime [Term] id: FYPO:0007401 name: abnormal protein localization to kinetochore during mitotic anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal during anaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to kinetochore during mitotic anaphase" EXACT [PomBase:mah] synonym: "abnormal protein localization to kinetochore during anaphase of mitosis" EXACT [PomBase:mah] is_a: FYPO:0008164 ! abnormal protein localization to kinetochore during mitotic M phase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T13:43:49Z" xsd:dateTime [Term] id: FYPO:0007402 name: abnormal protein complex organization during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of protein complex organization is abnormal." [GO:0043933, PomBase:mah] synonym: "abnormal protein complex organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein complex organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein-containing complex subunit organization during vegetative growth" EXACT [GO:0043933] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T14:36:00Z" xsd:dateTime [Term] id: FYPO:0007403 name: increased duration of anaphase-promoting complex presence def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the anaphase-promoting complex (APC) is present for longer than normal. The APC normally forms in prometaphase and disassembles before anaphase; in mutants it may remain present during anaphase." [PMID:24583014, PomBase:mah] synonym: "APC present during mitotic anaphase" NARROW [PMID:24583014, PomBase:vw] synonym: "increased duration of anaphase-promoting complex presence during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of anaphase-promoting complex presence during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of APC presence" EXACT [PomBase:mah] synonym: "increased persistence of anaphase-promoting complex" RELATED [PomBase:mah] is_a: FYPO:0007402 ! abnormal protein complex organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T14:44:17Z" xsd:dateTime [Term] id: FYPO:0007404 name: decreased protein degradation during mitotic anaphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during anaphase of mitosis." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein breakdown during mitotic anaphase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during mitotic anaphase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during mitotic anaphase" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during anaphase of mitosis" EXACT [PomBase:mah] synonym: "decreased protein degradation during mitotic anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein degradation during mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0004198 ! decreased protein degradation during mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T15:00:58Z" xsd:dateTime [Term] id: FYPO:0007405 name: abnormal protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abnormal, and some of the protein is detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex." [PMID:32101481, PomBase:mah, PomBase:vw] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortex, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to medial cortex, with protein distributed in cell cortex, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to medial ring, with protein distributed in cell cortex, during vegetative growth" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0000731 ! abnormal protein localization to medial cortex during vegetative growth is_a: FYPO:0000782 ! mislocalized protein during vegetative growth relationship: has_part FYPO:0006636 ! mislocalized protein distributed in cell cortex property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T15:29:31Z" xsd:dateTime [Term] id: FYPO:0007406 name: decreased lncRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature long non-coding RNA (lncRNA) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased lncRNA accumulation" RELATED [PomBase:mah] synonym: "decreased lncRNA level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased lncRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lncRNA transcript level" BROAD [PomBase:vw] synonym: "decreased long non-coding RNA level" EXACT [PomBase:mah] synonym: "decreased mature lncRNA level" EXACT [PomBase:mah] synonym: "reduced lncRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T15:38:24Z" xsd:dateTime [Term] id: FYPO:0007407 name: increased level of phosphate starvation gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during phosphate starvation measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth)." [PMID:32499400, PomBase:mah] synonym: "increased level of cellular response to phosphate starvation gene mRNA during vegetative growth" EXACT [PomBase:al] synonym: "increased level of phosphate starvation gene mRNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of phosphate starvation gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of phosphate starvation gene transcripts during vegetative growth" EXACT [PomBase:vw] synonym: "increased phosphate starvation gene mRNA accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T15:43:07Z" xsd:dateTime [Term] id: FYPO:0007408 name: abnormal protein localization to chromatin at polyadenylation site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abnormal at sites encoding polyadenylation signals." [PMID:32499400, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromatin at polyadenylation site" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromatin at poly(A) site" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromatin at polyadenylation site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to chromatin at polyadenylation site during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T15:48:35Z" xsd:dateTime [Term] id: FYPO:0007409 name: abnormal mRNA alternative polyadenylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of mRNA is abnormal. mRNA alternative polyadenylation generates mRNA molecules with variable 3'-end lengths from a given pre-mRNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites." [GO:0110104, PomBase:mah] synonym: "abnormal mRNA alternative polyadenylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mRNA alternative polyadenylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007919 ! abnormal RNA alternative polyadenylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T15:59:36Z" xsd:dateTime [Term] id: FYPO:0007410 name: abnormal RNA polymerase II C-terminal domain phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more residues within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II is abnormal." [GO:0070816, PomBase:mah] synonym: "abnormal phosphorylation of RNA polymerase II C-terminal domain" EXACT [GO:0070816] is_a: FYPO:0002677 ! abnormal protein phosphorylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T16:20:38Z" xsd:dateTime [Term] id: FYPO:0007411 name: abnormal distribution of RNA polymerase II C-terminal domain residue phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of residues within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II is abnormal, resulting in an abnormal distribution of RNA polymerase II molecules with different C-terminal domain residue phosphorylation patterns." [PMID:32499400, PomBase:mah] synonym: "abnormal distribution of RNA polymerase II C-terminal domain residue phosphorylation during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-22T16:25:52Z" xsd:dateTime [Term] id: FYPO:0007412 name: normal mitotic spindle orientation def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the orientation of the mitotic spindle is normal (i.e. indistinguishable from wild type, parallel with the long axis of the cell)." [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth relationship: part_of FYPO:0001399 ! normal mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-24T13:27:28Z" xsd:dateTime [Term] id: FYPO:0007413 name: abnormal telomere morphology during G0 def: "A physical cellular phenotype in which the size, shape, or structure of the telomere is abnormal during G0 phase." [PomBase:mah] synonym: "abnormal chromosome morphology at telomere during G0" EXACT [] synonym: "abnormal chromosome morphology at telomeric region during G0" EXACT [] synonym: "abnormal telomere morphology during cell quiescence" EXACT [] synonym: "abnormal telomere morphology during quiescence" EXACT [] synonym: "abnormal telomeric region morphology during G0" EXACT [] is_a: FYPO:0006508 ! abnormal telomere morphology relationship: RO:0002353 FYPO:0007416 ! abnormal telomere maintenance during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T12:50:39Z" xsd:dateTime [Term] id: FYPO:0007414 name: subtelomere expansion during G0 def: "A physical cellular phenotype in which a subtelomeric region (STE1) adjacent to telomeric repeats is duplicated by homologous recombination." [PMID:29392410, PMID:31980821, PomBase:mah] synonym: "amplification of subtelomeric regions in G0" EXACT [PomBase:vw] synonym: "STE1 expansion during G0" EXACT [PMID:29392410] synonym: "STEEx during G0" EXACT [PMID:29392410] synonym: "subtelomere amplification during G0" EXACT [PomBase:vw] synonym: "subtelomere expansion during cell quiescence" EXACT [PomBase:mah] synonym: "subtelomere expansion during quiescence" EXACT [PomBase:mah] synonym: "subtelomere rearrangement during G0" RELATED [PMID:31980821] synonym: "subtelomeric region expansion during G0" EXACT [PomBase:mah] is_a: FYPO:0007413 ! abnormal telomere morphology during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T13:19:44Z" xsd:dateTime [Term] id: FYPO:0007415 name: abnormal telomere maintenance def: "A cellular process phenotype in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal." [GO:0000723, PomBase:mah] synonym: "telomere maintenance defects" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T13:47:25Z" xsd:dateTime [Term] id: FYPO:0007416 name: abnormal telomere maintenance during G0 def: "A cellular process phenotype in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal during G0 phase." [GO:0000723, PomBase:mah] synonym: "abnormal telomere maintenance during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal telomere maintenance during quiescence" EXACT [PomBase:mah] is_a: FYPO:0007415 ! abnormal telomere maintenance property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T13:53:44Z" xsd:dateTime [Term] id: FYPO:0007417 name: normal telomere clustering during G0 def: "A cellular process phenotype in which telomere clustering is normal (i.e. indistinguishable from wild type) during G0 phase. Normally, telomeres cluster at the nuclear periphery during vegetative growth or G0, but whereas telomeres form two to three clusters in vegetative cells, a single cluster forms in G0." [GO:0120110, PMID:31980821, PomBase:mah] synonym: "normal telomere clustering during cell quiescence" EXACT [PomBase:mah] synonym: "normal telomere clustering during quiescence" EXACT [PomBase:mah] is_a: FYPO:0004973 ! normal telomere localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T14:14:59Z" xsd:dateTime [Term] id: FYPO:0007418 name: abnormal telomere localization to nuclear periphery def: "A cellular process phenotype in which telomere localization to the nuclear periphery is abnormal." [PomBase:mah] synonym: "abnormal telomere localisation" EXACT [PomBase:mah] is_a: FYPO:0007768 ! abnormal heterochromatin tethering at nuclear periphery property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T14:27:32Z" xsd:dateTime [Term] id: FYPO:0007419 name: decreased telomere tethering at nuclear periphery during G0 def: "A cellular process phenotype in which telomere tethering at the nuclear periphery is decreased during G0 phase." [PomBase:mah] synonym: "decreased telomere anchoring at nuclear periphery during G0" EXACT [PomBase:vw] synonym: "decreased telomere tethering to NE in G0" RELATED [PomBase:vw] synonym: "decreased telomere tethering to NE in quiescence" RELATED [PomBase:vw] synonym: "increased telomere detachment from nuclear envelope in quiescence" RELATED [PomBase:vw] is_a: FYPO:0007418 ! abnormal telomere localization to nuclear periphery property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T14:41:48Z" xsd:dateTime [Term] id: FYPO:0007420 name: abnormal transcription at telomere def: "A cellular process phenotype in which transcription occurs to a greater extent than normal in telomeric regions. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "abnormal telomeric transcription" EXACT [PomBase:mah] synonym: "abnormal transcription from telomere" EXACT [PomBase:mah] is_a: FYPO:0005502 ! abnormal transcription property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T14:51:14Z" xsd:dateTime [Term] id: FYPO:0007421 name: increased transcription at telomere during G0 def: "A cellular process phenotype in which transcription occurs to a greater extent than normal in telomeric regions during G0 phase. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "increased telomeric transcription during G0" EXACT [PomBase:mah] synonym: "increased transcription at telomere during cell quiescence" EXACT [PomBase:mah] synonym: "increased transcription at telomere during quiescence" EXACT [PomBase:mah] synonym: "increased transcription from telomere during G0" EXACT [PomBase:mah] is_a: FYPO:0002875 ! increased transcription is_a: FYPO:0007420 ! abnormal transcription at telomere property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T14:55:06Z" xsd:dateTime [Term] id: FYPO:0007422 name: abolished mitotic spindle microtubule nucleation from spindle pole body def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of spindle microtubules from the spindle pole body (SPB) does not occur." [PMID:19942852, PomBase:mah] synonym: "abolished mitotic spindle microtubule nucleation from SPB" EXACT [PomBase:mah] synonym: "abolished mitotic spindle microtubule nucleation from spindle pole body during mitotic M phase" EXACT [PomBase:vw] synonym: "mitotic spindle microtubule nucleation from spindle pole body abolished" EXACT [PomBase:mah] is_a: FYPO:0005692 ! abnormal microtubule nucleation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T15:13:25Z" xsd:dateTime [Term] id: FYPO:0007423 name: decreased isochromosome formation def: "A cell phenotype in which isochromosome formation occurs less frequently than in wild type cells. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place." [PMID:32355220, PomBase:mah] synonym: "decreased isochromosome formation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased isochromosome formation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased occurrence of isochromosome formation" EXACT [PomBase:mah] synonym: "reduced isochromosome formation" EXACT [PomBase:mah] is_a: FYPO:0006810 ! decreased gross chromosomal rearrangement property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T15:25:04Z" xsd:dateTime [Term] id: FYPO:0007424 name: increased chromosomal truncation def: "A cell phenotype in which chromosomal truncations occur more frequently than in wild type cells." [PMID:32355220, PomBase:mah] synonym: "increased chromosomal truncation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromosomal truncation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001740 ! increased gross chromosomal rearrangement property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T15:29:03Z" xsd:dateTime [Term] id: FYPO:0007425 name: normal gene conversion def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion is normal (i.e. indistinguishably from wild type)." [PomBase:mah] synonym: "normal gene conversion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal gene conversion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-06-30T15:40:04Z" xsd:dateTime [Term] id: FYPO:0007426 name: abolished new mitotic spindle pole body insertion into nuclear envelope def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of the newly assembled spindle pole body into the nuclear envelope does not occur." [PMID:19487457, PMID:22042620, PomBase:mah] synonym: "abnormal establishment of old mitotic spindle pole body localization to nuclear envelope" EXACT [PomBase:mah] synonym: "abolished new mitotic SPB insertion into nuclear envelope" EXACT [PomBase:mah] synonym: "abolished new mitotic spindle pole body insertion into nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished new mitotic spindle pole body insertion into nuclear envelope during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003567 ! abnormal mitotic spindle pole body insertion into nuclear envelope property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-01T14:12:09Z" xsd:dateTime [Term] id: FYPO:0007427 name: abnormal old mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of the old spindle pole body (SPB) into the nuclear envelope is abnormal, and the SPB enters the nucleus. The old SPB may be transiently inserted into the nuclear envelope but does not remain in place as normal." [PMID:19487457, PomBase:mah, PomBase:vw] synonym: "abnormal establishment of old mitotic spindle pole body localization to nuclear envelope, with spindle pole body in nucleoplasm" EXACT [PomBase:mah] synonym: "abnormal old mitotic SPB insertion into nuclear envelope, with spindle pole body in nucleoplasm" EXACT [PomBase:mah] synonym: "abnormal old mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal old mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003568 ! abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-01T14:17:59Z" xsd:dateTime [Term] id: FYPO:0007428 name: delayed onset of mitotic spindle microtubule nucleation from old spindle pole body def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the nucleation of microtubules from the old mitotic spindle pole body begins later than normal." [PMID:19487457, PomBase:mah] synonym: "delayed mitotic spindle microtubule nucleation from old spindle pole body" EXACT [PomBase:mah] synonym: "delayed monopolar mitotic spindle nucleation from old spindle pole body" RELATED [PomBase:vw] synonym: "delayed onset of mitotic spindle microtubule nucleation from old SPB" EXACT [PomBase:mah] synonym: "delayed onset of mitotic spindle microtubule nucleation from old spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of mitotic spindle microtubule nucleation from old spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005692 ! abnormal microtubule nucleation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-01T14:27:16Z" xsd:dateTime [Term] id: FYPO:0007429 name: abolished protein degradation during cellular response to DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation does not occur during a cellular response to DNA damage." [PMID:15805471, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein breakdown during cellular response to DNA damage" EXACT [GO:0030163] synonym: "abolished protein catabolic process during cellular response to DNA damage" EXACT [GO:0030163] synonym: "abolished protein catabolism during cellular response to DNA damage" EXACT [GO:0030163] synonym: "abolished protein degradation during cellular response to DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein degradation during cellular response to DNA damage during vegetative growth" EXACT [PomBase:mah] synonym: "protein degradation abolished during cellular response to DNA damage" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-14T11:05:17Z" xsd:dateTime [Term] id: FYPO:0007430 name: increased cellular dGTP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dGTP measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular dGTP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular dGTP level during vegetative growth" EXACT [PomBase:mah] synonym: "increased dGTP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-14T12:20:25Z" xsd:dateTime [Term] id: FYPO:0007431 name: altered mutation rate def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a higher or lower rate than normal." [PomBase:mah] synonym: "abnormal mutation rate" EXACT [PomBase:mah] synonym: "altered mutation rate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered mutation rate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype is_a: FYPO:0001985 ! abnormal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-14T13:09:16Z" xsd:dateTime [Term] id: FYPO:0007432 name: decreased transversion frequency def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which transversion mutations occur at a lower frequency than normal." [PMID:15805471, PomBase:mah] comment: SO:1000017. is_a: FYPO:0007431 ! altered mutation rate property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-14T13:22:24Z" xsd:dateTime [Term] id: FYPO:0007433 name: normal cellular dATP level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dATP measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular dATP level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cellular dATP level during vegetative growth" EXACT [PomBase:mah] synonym: "normal dATP accumulation" RELATED [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-14T13:28:51Z" xsd:dateTime [Term] id: FYPO:0007434 name: attenuated change in cell size at division upon shift to poor nitrogen source def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells do not change the length at which they divide to the same extent as normal upon shifting from a good nitrogen source to a poor nitrogen source. Normally, cells divide at a smaller size after shifting to a poor nitrogen source; in mutants the size difference is less pronounced between media with good versus poor nitrogen sources. Good (or rich) nitrogen sources are distinguished from poor sources based on how readily nitrogen is assimilated into cellular metabolism. In microorganisms, good nitrogen sources generally support higher cell population growth rates than poor sources. In fission yeast, cells divide at a smaller size when grown on a poor nitrogen source than in nitrogen-rich media; proline is commonly used as a poor nitrogen source." [PMID:10640599, PMID:25639242, PomBase:mah, PomBase:vw] synonym: "attenuated change in cell size at division upon shift to poor nitrogen source during mitotic cell cycle" RELATED [PomBase:mah] synonym: "attenuated change in cell size at division upon shift to poor nitrogen source during vegetative growth" EXACT [PomBase:mah] synonym: "decreased change in cell length at division after shift to poor nitrogen source" EXACT [PomBase:vw] is_a: FYPO:0005206 ! abnormal mitotic cell cycle regulation upon nitrogen source shift property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-23T15:35:42Z" xsd:dateTime [Term] id: FYPO:0007435 name: inviable elongated mononucleate cell during nitrogen starvation def: "A cell phenotype in which a cell is inviable, elongated, i.e. has a greater length and length:diameter ratio than normal, and has one nucleus when the cell is subject to nitrogen starvation." [PMID:12399381, PomBase:mah] synonym: "inviable elongated mononucleate cell during nitrogen depletion" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0000998 ! elongated cell during nitrogen starvation relationship: output_of FYPO:0001001 ! abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-23T16:04:37Z" xsd:dateTime [Term] id: FYPO:0007436 name: swollen elongated multiseptate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is swollen, is elongated, and contains more than one septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah] synonym: "elongated swollen multiseptate vegetative cell" EXACT [PomBase:vw] synonym: "swollen elongated multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "swollen elongated multiseptate vegetative cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000223 ! elongated multiseptate vegetative cell is_a: FYPO:0000646 ! swollen vegetative cell is_a: FYPO:0001429 ! swollen elongated cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-27T10:15:53Z" xsd:dateTime [Term] id: FYPO:0007437 name: constitutive activation of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the mitotic spindle assembly checkpoint is activated continuously. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PMID:28017606, PomBase:mah] comment: The difference between this term and abolished deactivation of mitotic spindle assembly checkpoint (FYPO:0005726) is that this term describes cells in which the checkpoint is always active, i.e. the checkpoint is never observed to be "off", whereas FYPO:0005726 describes cells in which the checkpoint is not active at first, but once activated the checkpoint is not deactivated. synonym: "constitutive activation of mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "constitutively activated of mitotic spindle assembly checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-27T10:59:55Z" xsd:dateTime [Term] id: FYPO:0007438 name: premature activation of mitotic spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which activation of the mitotic spindle assembly checkpoint begins earlier than normal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [PMID:28017606, PomBase:mah] synonym: "advanced activation of mitotic spindle assembly checkpoint" EXACT [PomBase:mah] synonym: "premature activation of mitotic cell cycle spindle assembly checkpoint" EXACT [PomBase:mah] is_a: FYPO:0000168 ! abnormal mitotic spindle assembly checkpoint property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-07-27T11:14:54Z" xsd:dateTime [Term] id: FYPO:0007439 name: abnormal eisosome morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of eisosome is abnormal. For example, an eisosome may protrude into the cell interior. The eisosome consists of a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face." [GO:0032126, PomBase:mah] synonym: "abnormal eisosome morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal eisosome morphology during vegetative growth" EXACT [PomBase:mah] synonym: "eisosome remodeling" RELATED [PMID:32320462] is_a: FYPO:0007262 ! abnormal eisosome property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-03T12:19:49Z" xsd:dateTime [Term] id: FYPO:0007440 name: abnormal intracellular sterol transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the directed movement of sterols within cells is abnormal." [GO:0032366, PomBase:mah] synonym: "abnormal intracellular sterol transport during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal intracellular sterol transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-03T12:27:39Z" xsd:dateTime [Term] id: FYPO:0007441 name: normal protein localization to endoplasmic reticulum-plasma membrane contact site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to endoplasmic reticulum-plasma membrane contact sites is normal (i.e. indistinguishable from wild type)." [PMID:32320462, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localization to endoplasmic reticulum-plasma membrane contact site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to endoplasmic reticulum-plasma membrane contact site during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to ER-plasma membrane contact site" EXACT [GO:0140268] is_a: FYPO:0000644 ! normal protein localization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-03T13:09:37Z" xsd:dateTime [Term] id: FYPO:0007442 name: normal protein localization to endoplasmic reticulum membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum membrane is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localization to endoplasmic reticulum membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to endoplasmic reticulum membrane during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to ER membrane" EXACT [PomBase:mah] is_a: FYPO:0006378 ! normal protein localization to endoplasmic reticulum during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-03T13:15:33Z" xsd:dateTime [Term] id: FYPO:0007443 name: abolished protein localization to endoplasmic reticulum membrane, with protein mislocalized to cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and the protein is present in the cytosol instead." [PMID:32320462, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to endoplasmic reticulum membrane, with protein mislocalized to cytosol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to endoplasmic reticulum membrane, with protein mislocalized to cytosol during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to ER membrane, with protein mislocalized to cytosol" EXACT [PomBase:mah] is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-03T14:16:14Z" xsd:dateTime [Term] id: FYPO:0007444 name: normal macroautophagy during cellular response to endoplasmic reticulum stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which macroautophagy is normal (i.e. indistinguishable from wild type) during a cellular response to endoplasmic reticulum stress." [PMID:32735772, PomBase:mah] synonym: "normal macroautophagy during cellular response to endoplasmic reticulum stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal macroautophagy during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal macroautophagy during cellular response to ER stress" EXACT [PomBase:mah] is_a: FYPO:0000385 ! normal macroautophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-10T13:17:38Z" xsd:dateTime [Term] id: FYPO:0007445 name: abnormal reticulophagy during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum is abnormal." [GO:0061709, PomBase:mah] synonym: "abnormal endoplasmic reticulum autophagy during vegetative growth" EXACT [GO:0061709] synonym: "abnormal ER autophagy during vegetative growth" EXACT [GO:0061709] synonym: "abnormal ER degradation during vegetative growth" RELATED [GO:0061709] synonym: "abnormal ER-phagy during vegetative growth" EXACT [GO:0061709] synonym: "abnormal reticulophagy during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0008083 ! abnormal reticulophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-10T13:47:31Z" xsd:dateTime [Term] id: FYPO:0007446 name: decreased reticulophagy during cellular response to endoplasmic reticulum stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum occurs to a lower extent than normal during a cellular response to endoplasmic reticulum stress." [PMID:32735772, PomBase:mah] synonym: "decreased endoplasmic reticulum autophagy during cellular response to endoplasmic reticulum stress" EXACT [GO:0061709] synonym: "decreased ER autophagy during cellular response to endoplasmic reticulum stress" EXACT [GO:0061709] synonym: "decreased ER degradation" RELATED [GO:0061709] synonym: "decreased ER-phagy during cellular response to endoplasmic reticulum stress" EXACT [GO:0061709] synonym: "decreased reticulophagy during cellular response to endoplasmic reticulum stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased reticulophagy during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased reticulophagy during cellular response to ER stress" EXACT [PomBase:mah] synonym: "reduced reticulophagy during cellular response to endoplasmic reticulum stress" EXACT [PomBase:mah] is_a: FYPO:0008197 ! decreased reticulophagy during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-10T13:49:22Z" xsd:dateTime [Term] id: FYPO:0007447 name: abolished reticulophagy during cellular response to endoplasmic reticulum stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum does not occur during a cellular response to endoplasmic reticulum stress." [PMID:32735772, PomBase:mah] synonym: "abolished endoplasmic reticulum autophagy during cellular response to endoplasmic reticulum stress" EXACT [GO:0061709] synonym: "abolished ER autophagy during cellular response to endoplasmic reticulum stress" EXACT [GO:0061709] synonym: "abolished ER degradation" RELATED [GO:0061709] synonym: "abolished ER-phagy during cellular response to endoplasmic reticulum stress" EXACT [GO:0061709] synonym: "abolished reticulophagy during cellular response to endoplasmic reticulum stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished reticulophagy during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "abolished reticulophagy during cellular response to ER stress" EXACT [PomBase:mah] synonym: "reticulophagy abolished during cellular response to endoplasmic reticulum stress" EXACT [PomBase:mah] is_a: FYPO:0007445 ! abnormal reticulophagy during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-10T14:04:35Z" xsd:dateTime [Term] id: FYPO:0007448 name: normal reticulophagy during nitrogen starvation def: "A cellular process phenotype in which autophagic degradation of the endoplasmic reticulum is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [PMID:32735772, PomBase:mah] synonym: "normal endoplasmic reticulum autophagy during nitrogen starvation" EXACT [GO:0061709] synonym: "normal ER autophagy during nitrogen starvation" EXACT [GO:0061709] synonym: "normal ER degradation during nitrogen starvation" RELATED [GO:0061709] synonym: "normal ER-phagy during nitrogen starvation" EXACT [GO:0061709] synonym: "normal reticulophagy during nitrogen depletion" EXACT [PomBase:mah] synonym: "normal reticulophagy during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0008083 ! abnormal reticulophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-10T14:24:41Z" xsd:dateTime [Term] id: FYPO:0007449 name: abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and some of the protein is present in the cytoplasm instead." [PMID:32735772, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to ER, with protein mislocalized to cytoplasm" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth is_a: FYPO:0008405 ! abolished protein localization to endoplasmic reticulum property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-10T14:30:26Z" xsd:dateTime [Term] id: FYPO:0007450 name: decreased maintenance of protein location in cell cortex of cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to one or both cell tip(s), but remains there for a shorter time than normal." [PMID:12789340, PMID:15809031, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased maintenance of protein location in cell cortex of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased maintenance of protein location in cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "reduced maintenance of protein location in cell cortex of cell tip" EXACT [PomBase:mah] is_a: FYPO:0005464 ! abnormal maintenance of protein location at cell tip during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-17T13:34:21Z" xsd:dateTime [Term] id: FYPO:0007451 name: normal protein localization to cell cortex of cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of the cell tip is normal (i.e. indistinguishable from wild type)." [PMID:12789340, PMID:15809031, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell cortex of cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to cell cortex of cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to cell tip cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006876 ! normal protein localization to cell cortex of cell tip property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-17T13:48:43Z" xsd:dateTime [Term] id: FYPO:0007452 name: normal protein localization to microtubule plus-end def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends end of microtubules is normal (i.e. indistinguishable from wild type)." [PMID:15809031, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to microtubule plus-end" EXACT [PomBase:mah] synonym: "normal protein localization to microtubule plus-end during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to microtubule plus-end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003185 ! normal protein localization to microtubule cytoskeleton during mitotic interphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-08-17T13:59:32Z" xsd:dateTime [Term] id: FYPO:0007453 name: decreased protein level in Arp2/3 complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the Arp2/3 protein complex is lower than normal." [PMID:10588653, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein level in Arp2/3 complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level in Arp2/3 complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level in Arp2/3 protein complex" EXACT [GO:0005885] synonym: "reduced protein level in Arp2/3 complex" EXACT [PomBase:mah] is_a: FYPO:0005003 ! abnormal protein complex composition property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-02T12:32:48Z" xsd:dateTime [Term] id: FYPO:0007454 name: decreased ATP binding def: "A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "reduced ATP binding" EXACT [PomBase:mah] is_a: FYPO:0003671 ! abnormal ATP binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-02T12:40:21Z" xsd:dateTime [Term] id: FYPO:0007455 name: increased double-strand break repair via single-strand annealing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via single-strand annealing is increased." [GO:0045002, PomBase:mah] synonym: "increased double-strand break repair via single-strand annealing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased double-strand break repair via single-strand annealing during vegetative growth" EXACT [PomBase:mah] synonym: "increased double-strand break repair via SSA" EXACT [PMID:32692737] synonym: "increased error-prone double strand break repair" BROAD [PMID:32692737] is_a: FYPO:0000777 ! abnormal double-strand break repair during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-02T13:39:34Z" xsd:dateTime [Term] id: FYPO:0007456 name: increased 3' overhang single-stranded DNA endodeoxyribonuclease activity def: "A molecular function phenotype in which the observed rate of 3' overhang single-stranded DNA endodeoxyribonuclease activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-02T14:05:16Z" xsd:dateTime [Term] id: FYPO:0007457 name: excess nuclear envelope present during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more nuclear envelope than normal during interphase of the mitotic cell cycle. Excess nuclear envelopes may take the form of intranuclear membrane stacks or invaginations, or small cytoplasmic spheres that are attached to the nucleus, have double lipid bilayer membranes, and may contain structures resembling nuclear pores." [PMID:32848252, PomBase:mah] synonym: "excess nuclear envelope present during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "excess nuclear envelope present during mitotic interphase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001556 ! excess nuclear envelope present property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-07T14:49:38Z" xsd:dateTime [Term] id: FYPO:0007458 name: abolished nuclear pore localization to mitotic nuclear bridge def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization to the portion of the nuclear envelope enclosing the mitotic nuclear bridge does not occur. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase. Normally, nuclear pores that lack baskets are found in the midzone of the nuclear bridge." [GO:0140510, PMID:32848252, PomBase:mah] synonym: "abolished NPC localization to mitotic nuclear bridge" EXACT [PomBase:mah] synonym: "abolished nuclear pore complex localization to mitotic nuclear bridge" EXACT [PomBase:mah] synonym: "abolished nuclear pore distribution to mitotic nuclear bridge" EXACT [GO:0051664] synonym: "abolished nuclear pore localisation to mitotic nuclear bridge" EXACT [PomBase:mah] synonym: "abolished nuclear pore localization in nuclear envelope at mitotic nuclear bridge" EXACT [PomBase:mah] synonym: "abolished nuclear pore localization to mitotic nuclear bridge during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished nuclear pore localization to mitotic nuclear bridge during vegetative growth" EXACT [PomBase:mah] synonym: "abolished nuclear pore localization to mitotic nuclear bridge membrane domain" EXACT [PomBase:mah] is_a: FYPO:0003783 ! abnormal nuclear pore localization during mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-07T15:06:33Z" xsd:dateTime [Term] id: FYPO:0007459 name: abnormal nuclear envelope morphology at mitotic nuclear bridge def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the portion of the nuclear envelope enclosing the mitotic nuclear bridge is abnormal. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase." [GO:0140510, PMID:32848252, PomBase:mah] synonym: "abnormal nuclear envelope morphology at mitotic nuclear bridge during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear envelope morphology at mitotic nuclear bridge during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003779 ! abnormal nuclear envelope morphology during mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-07T15:17:01Z" xsd:dateTime [Term] id: FYPO:0007460 name: abnormal nuclear envelope morphology at mitotic nuclear bridge midzone def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the portion of the nuclear envelope enclosing the midzone of the mitotic nuclear bridge is abnormal. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase." [GO:0140510, PMID:32848252, PomBase:mah] synonym: "abnormal nuclear envelope morphology at mitotic nuclear bridge midzone during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear envelope morphology at mitotic nuclear bridge midzone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007459 ! abnormal nuclear envelope morphology at mitotic nuclear bridge property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-07T15:20:12Z" xsd:dateTime [Term] id: FYPO:0007461 name: sensitive to histidine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to histidine. Cells stop growing (and may die) at a concentration of histidine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to histidine" EXACT [PomBase:mah] synonym: "sensitive to histidine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to histidine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-08T14:33:23Z" xsd:dateTime [Term] id: FYPO:0007462 name: increased filamentous actin level def: "A cell phenotype in which the amount of filamentous actin measured the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. The total actin level (globular and filamentous actin) may be normal or abnormal." [PomBase:mah] synonym: "increased accumulation of filamentous actin in cell" RELATED [PomBase:mah] synonym: "increased cellular F-actin level" EXACT [PomBase:mah] synonym: "increased cellular filamentous actin level" EXACT [PomBase:mah] synonym: "increased F-actin level" EXACT [PomBase:mah] synonym: "increased filamentous actin level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased filamentous actin level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-16T13:17:18Z" xsd:dateTime [Term] id: FYPO:0007463 name: normal transcription termination def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription from a DNA template is normal (i.e. indistinguishable from wild type)." [GO:0006353, PomBase:mah] synonym: "normal DNA-templated transcription, termination" EXACT [GO:0006353] synonym: "normal termination of transcription" EXACT [PomBase:mah] synonym: "normal transcription termination during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription termination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype during vegetative growth is_a: FYPO:0000859 ! normal metabolic process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-23T14:56:13Z" xsd:dateTime [Term] id: FYPO:0007464 name: increased RNA level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] synonym: "increased RNA accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "increased RNA level during cellular response to hypoxia during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to increased oxygen tension" EXACT [GO:0071456] synonym: "increased transcript level during cellular response to hypoxia" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T12:31:14Z" xsd:dateTime [Term] id: FYPO:0007465 name: altered spatial extent of protein localization to chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to chromatin over a different spatial extent than normal. The protein may localize to a larger or smaller region than normal, or its localization may be shifted along the length of the chromosome." [PMID:18957202, PMID:31615333, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal spatial extent of protein localization to chromatin" EXACT [PomBase:mah] synonym: "altered spatial extent of protein localisation to chromatin" EXACT [PomBase:mah] synonym: "altered spatial extent of protein localization to chromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "altered spatial extent of protein localization to chromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T13:06:19Z" xsd:dateTime [Term] id: FYPO:0007466 name: abnormal histone H3-K9 methylation def: "A cellular process phenotype in which methylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] synonym: "abnormal histone H3K9me" EXACT [GO:0051567, PomBase:mah] synonym: "abnormal histone lysine H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0006870 ! abnormal histone methylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T13:29:52Z" xsd:dateTime [Term] id: FYPO:0007467 name: increased histone H3-K9 methylation during G0 def: "A cellular process phenotype in which trimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal during G0 phase." [PomBase:mah] synonym: "increased histone H3 K9 methylation during G0" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation during cell quiescence" EXACT [PomBase:mah] synonym: "increased histone H3-K9 methylation during quiescence" EXACT [PomBase:mah] synonym: "increased histone H3K9me during G0" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation during G0" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0007466 ! abnormal histone H3-K9 methylation is_a: FYPO:0007470 ! abnormal histone modification during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T13:48:56Z" xsd:dateTime [Term] id: FYPO:0007468 name: increased histone H3-K9 dimethylation during G0 def: "A cellular process phenotype in which dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal during G0 phase." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation during G0" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation during cell quiescence" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation during quiescence" EXACT [PomBase:mah] synonym: "increased histone H3K9me2 during G0" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 dimethylation during G0" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0007466 ! abnormal histone H3-K9 methylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T13:49:09Z" xsd:dateTime [Term] id: FYPO:0007469 name: increased histone H3-K9 trimethylation during G0 def: "A cellular process phenotype in which methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal during G0 phase." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation during G0" EXACT [PomBase:mah] synonym: "increased histone H3-K9 trimethylation during cell quiescence" EXACT [PomBase:mah] synonym: "increased histone H3-K9 trimethylation during quiescence" EXACT [PomBase:mah] synonym: "increased histone H3K9me3 during G0" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation during G0" EXACT [PomBase:mah] is_a: FYPO:0007466 ! abnormal histone H3-K9 methylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T13:49:18Z" xsd:dateTime [Term] id: FYPO:0007470 name: abnormal histone modification during G0 def: "A cellular process phenotype that affects histone modification during G0 phase." [PomBase:mah] synonym: "abnormal histone modification during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal histone modification during quiescence" EXACT [PomBase:mah] is_a: FYPO:0006458 ! abnormal histone modification property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T13:50:19Z" xsd:dateTime [Term] id: FYPO:0007471 name: abnormal heterochromatin organization during G0 def: "A cellular process phenotype in which any process of heterochromatin organization is abnormal during G0 phase. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin." [GO:0070828, PomBase:mah] synonym: "abnormal heterochromatin organisation during G0" EXACT [PomBase:mah] synonym: "abnormal heterochromatin organization during cell quiescence" EXACT [PomBase:mah] synonym: "abnormal heterochromatin organization during quiescence" EXACT [PomBase:mah] is_a: FYPO:0003871 ! abnormal chromatin organization during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T14:10:05Z" xsd:dateTime [Term] id: FYPO:0007472 name: abnormal histone exchange def: "A cellular process phenotype in which histone exchange is abnormal. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0043486, PMID:31315658, PomBase:mah] synonym: "histone turnover" RELATED [] is_a: FYPO:0006606 ! abnormal dynamic protein localization pattern property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T14:26:25Z" xsd:dateTime [Term] id: FYPO:0007473 name: decreased histone exchange during G0 {EXACT="decreased histone exchange during G0"} def: "A cellular process phenotype in which histone exchange is abnormal during G0 phase. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GO:0043486, PMID:31315658, PomBase:mah] synonym: "decreased histone exchange during G0 during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone exchange during G0 during quiescence" EXACT [PomBase:mah] is_a: FYPO:0007472 ! abnormal histone exchange property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-09-29T14:31:48Z" xsd:dateTime [Term] id: FYPO:0007474 name: variable cell size at division def: "A cell population phenotype in which cells in a population do not divide at a uniform size, although each cell divides to form equal-size daughter cells. Within one population, some cells may be larger and others smaller than normal (i.e. compared to wild-type cells under the same conditions)." [PMID:23333317, PomBase:mah, PomBase:vw] synonym: "increased variability of cell size in a vegetative population" EXACT [PomBase:vw] synonym: "variable cell size at division during mitotic cell cycle" RELATED [PomBase:mah] synonym: "variable cell size at division during vegetative growth" EXACT [PomBase:mah] synonym: "variable cell size at division, with equal-sized daughter cell formation" EXACT [PomBase:mah, PomBase:vw] synonym: "variable vegetative cell size at division" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T10:56:24Z" xsd:dateTime [Term] id: FYPO:0007475 name: delayed onset of protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body begins later than normal." [PMID:23333317, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to mitotic spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to mitotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T11:06:38Z" xsd:dateTime [Term] id: FYPO:0007476 name: decreased duration of cell cycle arrest in mitotic G1 phase def: "A cellular process phenotype in which the duration of an otherwise normal occurrence of cell cycle arrest in mitotic G1 phase is shorter than normal." [PMID:32361273, PomBase:mah] synonym: "decreased duration of cell cycle arrest in G1 phase during mitotic cell cycle" EXACT [PomBase:mah] synonym: "decreased duration of cell cycle arrest in mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of mitotic cell cycle arrest in G1 phase" EXACT [PomBase:mah] is_a: FYPO:0005097 ! abnormal cell cycle arrest in mitotic G1 phase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T11:12:03Z" xsd:dateTime [Term] id: FYPO:0007477 name: abnormal epigenetic heterochromatin inheritance def: "A phenotype in which the stable inheritance of heterochromatic structure is abnormal in regions of the genome where heterochromatin is normally maintained over successive generations." [PMID:29899117, PMID:31278118, PomBase:mah] synonym: "abnormal epigenetic heterochromatin propagation" EXACT [PomBase:mah] synonym: "abnormal epigenetic inheritance of heterochromatin" EXACT [PomBase:mah] synonym: "abnormal PEV" RELATED [PMID:31278118] is_a: FYPO:0001985 ! abnormal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T11:57:16Z" xsd:dateTime [Term] id: FYPO:0007478 name: decreased epigenetic heterochromatin inheritance def: "A phenotype in which a region of the genome that is normally stably assembled and maintained as heterochromatin over successive generations retains heterochromatic structure for fewer generations than normal." [PMID:29899117, PMID:31278118, PomBase:mah] synonym: "decreased epigenetic heterochromatin propagation" EXACT [PomBase:mah] synonym: "decreased PEV" RELATED [PMID:31278118] synonym: "epigenetic inheritance of heterochromatin" EXACT [PomBase:mah] synonym: "reduced epigenetic heterochromatin inheritance" EXACT [PomBase:mah] is_a: FYPO:0007477 ! abnormal epigenetic heterochromatin inheritance property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T12:10:00Z" xsd:dateTime [Term] id: FYPO:0007479 name: normal epigenetic heterochromatin inheritance def: "A phenotype in which the assembly and stable inheritance of heterochromatic structure is normal (i.e. indistinguishable from wild type) in regions of the genome where heterochromatin is normally maintained over successive generations." [PMID:29899117, PMID:31278118, PomBase:mah] synonym: "normal epigenetic heterochromatin propagation" EXACT [PomBase:mah] synonym: "normal epigenetic inheritance of heterochromatin" EXACT [PomBase:mah] synonym: "normal PEV" RELATED [PMID:31278118] is_a: FYPO:0001985 ! abnormal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T12:12:37Z" xsd:dateTime [Term] id: FYPO:0007480 name: decreased spatial extent of subtelomeric heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a smaller portion of the subtelomeric region of the chromosome than normal." [PMID:29899117, PomBase:mah] synonym: "decreased spatial extent of heterochromatin assembly at subtelomere" EXACT [PomBase:mah] synonym: "decreased spatial extent of subtelomeric heterochromatin assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased spatial extent of subtelomeric heterochromatin assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spatial extent of subtelomeric heterochromatin formation" EXACT [GO:0031509] synonym: "decreased spatial extent of telomeric heterochromatin assembly" RELATED [PomBase:mah, Pombase:vw] synonym: "reduced spatial extent of subtelomeric heterochromatin assembly" EXACT [PomBase:mah] is_a: FYPO:0005849 ! decreased spatial extent of heterochromatin assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T12:35:22Z" xsd:dateTime [Term] id: FYPO:0007481 name: attenuated increase in transcription during cellular response to stress in presence of small molecule def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an increase in the transcription of one or more target genes that would normally occur when cells are subjected to a stress in the presence of a specific small molecule occurs to a lower extent than normal under the same circumstances." [PMID:31932483, PomBase:mah] synonym: "attenuated increase in transcription during cellular response to stress in presence of small molecule during mitotic cell cycle" RELATED [PomBase:mah] synonym: "attenuated increase in transcription during cellular response to stress in presence of small molecule during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0004527 ! abnormal regulation of transcription during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-06T12:44:30Z" xsd:dateTime [Term] id: FYPO:0007482 name: decreased protein localization to meiotic spindle pole body during meiosis I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during the first meiotic nuclear division." [PMID:27889481, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to meiotic spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic SPB during meiosis I" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic spindle pole body during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during meiosis I" EXACT [PomBase:mah] synonym: "reduced protein localization to meiotic spindle pole body during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0002772 ! decreased protein localization to meiotic spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T11:04:33Z" xsd:dateTime [Term] id: FYPO:0007483 name: abnormal meiotic spindle pole body duplication during meiosis I def: "A cellular process phenotype in which meiotic spindle pole body duplication is abnormal during the first meiotic nuclear division." [PMID:27889481, PomBase:mah] synonym: "abnormal meiotic SPB duplication during meiosis I" EXACT [PomBase:mah] synonym: "abnormal meiotic spindle pole body duplication during first meiotic nuclear division" EXACT [GO:0007127] synonym: "abnormal spindle pole body duplication during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0007258 ! abnormal meiotic spindle pole body duplication property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T11:10:42Z" xsd:dateTime [Term] id: FYPO:0007484 name: abnormal microtubule nucleation def: "A microtubule cytoskeleton organization phenotype in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) is abnormal." [PomBase:mah] synonym: "microtubule nucleation defects" EXACT [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization relationship: has_output FYPO:0007486 ! monopolar spindle during meiosis II property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T11:27:22Z" xsd:dateTime [Term] id: FYPO:0007485 name: abolished meiotic spindle microtubule nucleation from new spindle pole body during meiosis II def: "A cellular process phenotype in which nucleation of spindle microtubules from the new spindle pole body does not occur during the second meiotic nuclear division." [PMID:27889481, PomBase:mah] synonym: "abolished meiotic spindle microtubule nucleation from new SPB during meiosis II" EXACT [PomBase:mah] synonym: "abolished meiotic spindle microtubule nucleation from new spindle pole body during second meiotic nuclear division" EXACT [GO:0007135] synonym: "abolished spindle microtubule nucleation from new spindle pole body during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0004510 ! abnormal spindle assembly during meiosis II is_a: FYPO:0007484 ! abnormal microtubule nucleation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T11:31:50Z" xsd:dateTime [Term] id: FYPO:0007486 name: monopolar spindle during meiosis II def: "A physical cellular phenotype in which the spindle forms with microtubules emanating from only one pole during the second meiotic nuclear division." [PMID:27889481, PomBase:mah] synonym: "fan-shaped spindle during meiosis II" EXACT [PomBase:vw] synonym: "monopolar spindle during second meiotic nuclear division" EXACT [GO:0007135] synonym: "V-shaped spindle during meiosis II" RELATED [PomBase:vw] is_a: FYPO:0000734 ! abnormal meiotic spindle is_a: FYPO:0003607 ! abnormal spindle morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T11:39:57Z" xsd:dateTime [Term] id: FYPO:0007487 name: abolished new meiotic spindle pole body insertion into nuclear envelope during meiosis II def: "A cellular process phenotype in which insertion of the newly formed spindle pole body into the nuclear envelope does not occur during the second meiotic nuclear division." [PMID:27889481, PomBase:mah] synonym: "abolished new meiotic SPB insertion into nuclear envelope during meiosis II" EXACT [PomBase:mah] synonym: "abolished new meiotic spindle pole body insertion into nuclear envelope during second meiotic nuclear division" EXACT [GO:0007135] synonym: "abolished new spindle pole body insertion into nuclear envelope during meiosis II" EXACT [PomBase:mah] is_a: FYPO:0006526 ! abnormal meiosis II property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T12:30:30Z" xsd:dateTime [Term] id: FYPO:0007488 name: decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the vacuole instead." [PMID:32918581, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to Golgi apparatus, with protein mislocalised to vacuole" EXACT [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to Golgi apparatus, with protein mislocalized to vacuole" EXACT [PomBase:mah] is_a: FYPO:0004786 ! decreased protein localization to Golgi apparatus property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T12:37:28Z" xsd:dateTime [Term] id: FYPO:0007489 name: decreased protein localization to Golgi apparatus, with protein mislocalized to cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the cytosol instead." [PMID:32918581, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to Golgi apparatus, with protein mislocalised to cytosol" EXACT [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to cytosol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to Golgi apparatus, with protein mislocalized to cytosol during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to Golgi apparatus, with protein mislocalized to cytosol" EXACT [PomBase:mah] is_a: FYPO:0004786 ! decreased protein localization to Golgi apparatus property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T12:41:22Z" xsd:dateTime [Term] id: FYPO:0007490 name: normal mannosyltransferase activity def: "A molecular function phenotype in which the observed rate of a mannosyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T12:54:09Z" xsd:dateTime [Term] id: FYPO:0007491 name: normal O-linked glycoprotein glycan structure def: "A phenotype in which the structure of an O-linked glycan moiety of a nascent or mature glycoprotein is normal (i.e. indistinguishable from wild type)." [PMID:32918581, PomBase:mah] synonym: "normal O-linked glycoprotein oligosaccharide structure" RELATED [Pombase:vw] is_a: FYPO:0000257 ! normal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T13:28:43Z" xsd:dateTime [Term] id: FYPO:0007492 name: altered level of substance in cell wall def: "A cell phenotype in which the amount of a specific substance measured in the cell wall differs from normal." [PomBase:mah] synonym: "abnormal level of substance in cell wall" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T13:33:40Z" xsd:dateTime [Term] id: FYPO:0007493 name: decreased ascospore wall alpha-glucan level def: "A cell phenotype in which the amount of alpha-D-glucan measured in the spore wall is lower than normal." [PMID:16420355, PomBase:mah] synonym: "decreased ascospore wall alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "decreased ascospore wall alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "decreased ascospore wall alpha-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased ascospore wall alpha-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased spore wall alpha-glucan level" EXACT [PomBase:mah] synonym: "reduced ascospore wall alpha-glucan level" EXACT [PomBase:mah] is_a: FYPO:0007492 ! altered level of substance in cell wall property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T13:35:36Z" xsd:dateTime [Term] id: FYPO:0007494 name: increased ascospore wall beta-glucan level def: "A cell phenotype in which the amount of beta-D-glucan measured in the spore wall is higher than normal." [PomBase:mah] synonym: "increased ascospore wall beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "increased ascospore wall beta-glucan accumulation" RELATED [PomBase:mah] synonym: "increased ascospore wall beta-glucan level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased ascospore wall beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "increased spore wall beta-glucan level" EXACT [PomBase:mah] is_a: FYPO:0007492 ! altered level of substance in cell wall property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-10-20T14:11:57Z" xsd:dateTime [Term] id: FYPO:0007495 name: normal protein localization to Mei2 nuclear dot def: "A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is normal (i.e. indistinguishable from wild type). The Mei2 nuclear dot is a nuclear body that contains Mei2, other proteins, and meiRNA, and forms during meiotic prophase in a fixed position in the horsetail nucleus." [PMID:24920274, PomBase:mah] comment: In some mutants, a focus that contains meiRNA but not Mei2 can form; this is called the meiRNA nuclear dot. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to Mei2 nuclear dot" EXACT [PomBase:mah] synonym: "normal protein localization to meiRNA nuclear dot" RELATED [PMID:24920274, PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-03T13:29:15Z" xsd:dateTime [Term] id: FYPO:0007496 name: abolished protein localization to nuclear exosome focus at sme2 locus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear exosome focus at the sme2 locus does not occur. Other nuclear exosome foci may form normally." [PMID:24920274, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nuclear exosome focus at sme2 locus" EXACT [PomBase:mah] synonym: "abolished protein localization to Mmi1 nuclear focus at sme2 locus" EXACT [PomBase:mah] synonym: "abolished protein localization to nuclear exosome focus at sme2 locus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to nuclear exosome focus at sme2 locus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003042 ! abolished protein localization to nuclear exosome focus property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-03T14:34:11Z" xsd:dateTime [Term] id: FYPO:0007497 name: aggregated nuclear exosome foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which fewer, larger nuclear exosome foci are present than normal. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1." [PMID:24920274, PomBase:mah] synonym: "aggregated Mmi1 nuclear foci" EXACT [PomBase:mah] synonym: "aggregated nuclear exosome foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "aggregated nuclear exosome foci during vegetative growth" EXACT [PomBase:mah] synonym: "Mmi1 nuclear foci present in decreased numbers" RELATED [PomBase:mah] synonym: "nuclear exosome foci present in decreased numbers" RELATED [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-03T14:55:23Z" xsd:dateTime [Term] id: FYPO:0007498 name: decreased chromatin binding at cohesin associated regions def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more cohesin-associated regions (CARs) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PMID:27226485, PMID:31895039, PomBase:mah] synonym: "decreased chromatin binding at CARs" EXACT [PomBase:mah] synonym: "decreased chromatin binding at cohesin associated regions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin binding at cohesin associated regions during vegetative growth" EXACT [PomBase:mah] synonym: "reduced chromatin binding at cohesin associated regions" EXACT [PomBase:mah] is_a: FYPO:0002577 ! decreased chromatin binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-03T15:20:45Z" xsd:dateTime [Term] id: FYPO:0007499 name: increased chromatin binding at cohesin associated regions def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more cohesin-associated regions (CARs) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PMID:27226485, PMID:31895039, PomBase:mah] synonym: "increased chromatin binding at CARs" EXACT [PomBase:mah] synonym: "increased chromatin binding at cohesin associated regions during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin binding at cohesin associated regions during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002980 ! increased chromatin binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-03T15:26:25Z" xsd:dateTime [Term] id: FYPO:0007500 name: abolished macroautophagy during sulfur starvation def: "A cellular process phenotype in which macroautophagy does not occur when the cell is subject to sulfur starvation." [GO:0016236, PomBase:mah] synonym: "abolished macroautophagy during cellular response to sulfur starvation" EXACT [] synonym: "abolished macroautophagy during sulfur depletion" EXACT [PomBase:mah] synonym: "abolished macroautophagy during sulfur deprivation" EXACT [PomBase:mah] synonym: "abolished macroautophagy during sulphur starvation" EXACT [PomBase:mah] synonym: "macroautophagy abolished during sulfur starvation" EXACT [PomBase:mah] is_a: FYPO:0000380 ! abolished macroautophagy is_a: FYPO:0000860 ! abnormal metabolic process property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T13:05:09Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007501 name: abnormal horsetail-astral microtubule organization def: "A cellular process phenotype in which assembly, arrangement of constituent parts, or disassembly of the horsetail-astral microtubule array is abnormal." [GO:0032118, PomBase:mah] synonym: "abnormal horsetail-astral microtubule array organization" EXACT [GO:003118] synonym: "abnormal horsetail-astral microtubule organisation" EXACT [PomBase:mah] synonym: "abnormal horsetail-astral microtubule organization and biogenesis" RELATED [PomBase:mah] is_a: FYPO:0007113 ! abnormal microtubule cytoskeleton organization during meiotic cell cycle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T13:15:36Z" xsd:dateTime [Term] id: FYPO:0007502 name: decreased protein localization to meiotic spindle pole body during prophase I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during prophase of the first meiotic nuclear division." [PMID:16111942, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to meiotic spindle pole body during prophase I" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic SPB during prophase I" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic spindle pole body during meiotic prophase I" EXACT [PomBase:mah] synonym: "decreased protein localization to meiotic spindle pole body during prophase of first meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during prophase I" EXACT [PomBase:mah] synonym: "reduced protein localization to meiotic spindle pole body during prophase I" EXACT [PomBase:mah] is_a: FYPO:0007482 ! decreased protein localization to meiotic spindle pole body during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T13:25:27Z" xsd:dateTime [Term] id: FYPO:0007503 name: abnormal histone demethylase activity def: "A molecular function phenotype in which the observed rate of a histone demethylase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T13:42:03Z" xsd:dateTime [Term] id: FYPO:0007504 name: abolished histone demethylase activity (H3-K9 specific) def: "A molecular function phenotype in which H3-K9 specific histone demethylase activity is absent." [PomBase:mah] synonym: "histone demethylase activity (H3-K9 specific) abolished" EXACT [PomBase:mah] is_a: FYPO:0007503 ! abnormal histone demethylase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T13:47:09Z" xsd:dateTime [Term] id: FYPO:0007505 name: decreased protein localization to chromatin at promoter def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at promoter" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to chromatin at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to chromatin at promoter" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0006631 ! decreased protein localization to chromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T13:50:38Z" xsd:dateTime [Term] id: FYPO:0007506 name: increased protein localization to chromatin at promoter def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin at promoter" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T14:09:41Z" xsd:dateTime [Term] id: FYPO:0007507 name: increased histone H3-K9 trimethylation at promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in one or more promoter regions occurs to a greater extent than normal." [PMID:17434129, PomBase:mah] synonym: "increased histone H3 K9 trimethylation at promoter during vegetative growth" EXACT [GO:0036124\,PomBase\:mah] synonym: "increased histone H3-K9 trimethylation at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me3 at promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation at promoter during vegetative growth" EXACT [GO:0036124\,PomBase\:mah] is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T14:28:13Z" xsd:dateTime [Term] id: FYPO:0007508 name: increased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at subtelomeric regions occurs to a greater extent than normal." [PMID:17434129, PomBase:mah] synonym: "increased histone H3 K9 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036124\,PomBase\:mah] synonym: "increased histone H3-K9 trimethylation at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 trimethylation at subtelomeric heterochromatin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me3 at subtelomeric heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation at subtelomeric heterochromatin during vegetative growth" EXACT [GO:0036124\,PomBase\:mah] is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T14:49:19Z" xsd:dateTime [Term] id: FYPO:0007509 name: increased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a greater extent than normal." [PMID:17434129, PomBase:mah] synonym: "increased histone H3 K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036124\,PomBase\:mah] synonym: "increased histone H3-K9 trimethylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3-K9 trimethylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me3 at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone lysine H3 K9 trimethylation at silent mating-type cassette during vegetative growth" EXACT [GO:0036124\,PomBase\:mah] is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-05T14:50:36Z" xsd:dateTime [Term] id: FYPO:0007510 name: cell cycle arrest at mitotic G2/M phase transition in absence of mitotic DNA replication checkpoint def: "A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested at the mitotic G2/M phase transition in the absence of the mitotic DNA replication checkpoint. The previous S phase is completed, no replication intermediates can be observed, and cells do not undergo rereplication." [PMID:17690116, PomBase:jh, PomBase:mah] synonym: "cell cycle arrest at G2/M phase transition in absence of mitotic DNA replication checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition in absence of mitotic DNA replication checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest at the G2/M transition with completed S phase" RELATED [PomBase:jh] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-10T13:29:12Z" xsd:dateTime [Term] id: FYPO:0007511 name: normal mitosis following cell cycle arrest in response to mitotic DNA replication checkpoint def: "A cellular process phenotype in which a cell undergoes normal (i.e. indistinguishable from wild type) mitosis upon release from a following release from a G2/M cell cycle block imposed by activation of the mitotic DNA replication checkpoint." [PMID:17690116, PomBase:jh, PomBase:mah] synonym: "normal mitosis following cell cycle arrest in response to DNA replication checkpoint during mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal mitosis following cell cycle arrest in response to mitotic DNA replication checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitosis following release from a mitotic DNA replication cell cycle block" EXACT [PomBase:jh] is_a: FYPO:0001007 ! normal mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-10T13:35:08Z" xsd:dateTime [Term] id: FYPO:0007512 name: abnormal chromosome III morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure chromosome III is abnormal." [PMID:17690116, PomBase:jh, PomBase:mah] synonym: "abnormal chromosome III mobility" RELATED [PomBase:jh] synonym: "abnormal chromosome III morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal chromosome III morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000848 ! abnormal chromosome morphology during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-10T13:38:04Z" xsd:dateTime [Term] id: FYPO:0007513 name: increased rDNA copy number during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly greater than the range in wild type cells." [PMID:17690116, PomBase:mah] synonym: "increased copy number of rDNA repeats" EXACT [PomBase:jh] synonym: "increased copy number of rDNA repeats during mitotic cell cycle" RELATED [PomBase:jh] synonym: "increased rDNA copy number during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0004823 ! abnormal rDNA copy number property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-10T14:03:47Z" xsd:dateTime [Term] id: FYPO:0007514 name: sensitive to manumycin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to manumycin A. Cells stop growing (and may die) at a concentration of manumycin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to manumycin A" EXACT [PomBase:mah] synonym: "sensitive to manu-A" EXACT [PMID:25500221] synonym: "sensitive to manumycin A during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to manumycin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-10T14:12:06Z" xsd:dateTime [Term] id: FYPO:0007515 name: decreased RNA stability during cellular response to oxidative stress def: "A cell phenotype in which RNA stability is decreased during a cellular response to oxidative stress. RNA molecules are more likely to degrade over a given time period than in wild type. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:14633985, PomBase:mah] synonym: "decreased RNA stability during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased RNA stability during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA stability in response to oxidative stress" EXACT [PomBase:vw] synonym: "reduced RNA stability during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0003038 ! abnormal RNA stability property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T14:18:54Z" xsd:dateTime [Term] id: FYPO:0007516 name: decreased DNA volume def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA occupies a smaller portion of the total nuclear volume than normal. The nuclear volume itself may be normal." [PMID:33153481, PomBase:mah] synonym: "decreased DNA volume during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased DNA volume during vegetative growth" EXACT [PomBase:mah] synonym: "reduced DNA volume" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth is_a: FYPO:0002403 ! abnormal nucleus property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T14:27:52Z" xsd:dateTime [Term] id: FYPO:0007517 name: increased chromatin mobility def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromatin moves within the nucleus to a greater extent than normal." [PMID:33153481, PomBase:mah] synonym: "increased chromatin mobility during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased chromatin mobility during vegetative growth" EXACT [PomBase:mah] synonym: "increased chromatin motility" EXACT [PomBase:mah] synonym: "increased chromatin movement" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T14:33:02Z" xsd:dateTime [Term] id: FYPO:0007518 name: increased transcription-induced DNA damage def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage occurring as a side effect of transcription in a cell is greater than normal. The number, extent, or both of damage sites may be increased." [PMID:33153481, PomBase:mah] synonym: "increased DNA damage by transcription" EXACT [PMID:33153481] synonym: "increased transcription-induced DNA damage during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription-induced DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003547 ! increased DNA damage during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T14:37:08Z" xsd:dateTime [Term] id: FYPO:0007519 name: normal DNA volume def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA occupies a normal (i.e. indistinguishable from wild type) portion of the total nuclear volume. The nuclear volume itself is also normal." [PMID:33153481, PomBase:mah] synonym: "normal DNA volume during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal DNA volume during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular component during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T14:47:10Z" xsd:dateTime [Term] id: FYPO:0007520 name: normal growth on beta-glucanase def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing one or more enzymes that degrades cell wall polysaccharides by hydrolyzing beta-glucan linkages." [PMID:19625445, PomBase:mah] synonym: "normal cell population growth in presence of beta-glucanase" EXACT [PomBase:mah] synonym: "normal cell population growth on beta-glucanase" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to beta-glucanase" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on beta-glucanase" EXACT [PomBase:mah] is_a: FYPO:0001192 ! normal growth on cell wall-degrading enzymes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T14:51:04Z" xsd:dateTime [Term] id: FYPO:0007521 name: resistance to tacrolimus and magnesium chloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of tacrolimus and magnesium chloride than normal." [PMID:19625445, PomBase:mah] synonym: "hypersensitive to tacrolimus and magnesium chloride" EXACT [PomBase:mah] synonym: "resistance to FK506 and magnesium chloride" EXACT [CHEBI:61057, PomBase:mah] synonym: "resistance to magnesium chloride and FK506" EXACT [PomBase:mah] synonym: "resistance to magnesium chloride and tacrolimus" EXACT [PomBase:mah] synonym: "resistance to tacrolimus and magnesium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tacrolimus and magnesium chloride during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to tacrolimus and MgCl2" EXACT [PomBase:mah] synonym: "resistant to tacrolimus and magnesium chloride" EXACT [PomBase:mah] synonym: "viable in the presence of FK506 and chloride" EXACT [PMID:19625445] synonym: "vic" RELATED [PMID:19625445] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T15:16:20Z" xsd:dateTime [Term] id: FYPO:0007522 name: sensitive to tacrolimus and magnesium chloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of tacrolimus and magnesium chloride. Cells stop growing (and may die) at concentrations of tacrolimus and magnesium chloride that allow wild type cells to grow." [PMID:19625445, PomBase:mah] synonym: "inviable in the presence of FK506 and chloride" EXACT [PMID:19625445] synonym: "sensitive to FK506 and magnesium chloride" EXACT [CHEBI:61057, PomBase:mah] synonym: "sensitive to magnesium chloride and FK506" EXACT [PomBase:mah] synonym: "sensitive to magnesium chloride and tacrolimus" EXACT [PomBase:mah] synonym: "sensitive to tacrolimus and magnesium chloride during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tacrolimus and magnesium chloride during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to tacrolimus and MgCl2" EXACT [PomBase:mah] synonym: "vic-negative" RELATED [PMID:19625445] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T15:22:16Z" xsd:dateTime [Term] id: FYPO:0007523 name: decreased protein level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to oxidative stress is lower than normal. Total protein or a specific protein may be affected." [PMID:19625445, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T15:25:36Z" xsd:dateTime [Term] id: FYPO:0007524 name: delayed onset of protein import into nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the import of protein into the nucleus begins later than normal. Import of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein import into nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein import into nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein import into nucleus" EXACT [PomBase:mah] is_a: FYPO:0003188 ! abnormal protein import into nucleus during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T15:30:52Z" xsd:dateTime [Term] id: FYPO:0007525 name: decreased ribosome binding def: "A molecular function phenotype in which occurrence of ribosome binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:19625445, PomBase:mah] synonym: "reduced ribosome binding" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T15:45:49Z" xsd:dateTime [Term] id: FYPO:0007526 name: increased protein phosphorylation during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to salt stress." [PMID:19625445, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein phosphorylation during cellular response to salt stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein phosphorylation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-17T15:49:18Z" xsd:dateTime [Term] id: FYPO:0007527 name: increased protein localization to cell tip during nitrogen starvation def: "A cell phenotype in which the localization of a protein to the cell tip is increased when the cell is subject to nitrogen starvation." [PMID:27746023, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localization to cell tip during nitrogen depletion" EXACT [PomBase:mah] synonym: "increased protein localization to cell tip during nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0005987 ! abnormal protein localization to cell tip property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T11:18:23Z" xsd:dateTime [Term] id: FYPO:0007528 name: normal membrane lipid binding def: "A molecular function phenotype in which occurrence of binding to a lipid in a membrane by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type)." [PMID:33172987, PomBase:mah] synonym: "normal binding to lipid in membrane" EXACT [PomBase:mah] is_a: FYPO:0006942 ! normal lipid binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T11:38:04Z" xsd:dateTime [Term] id: FYPO:0007529 name: normal histone H3-K9 dimethylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 at heterochromatin islands is normal (i.e. indistinguishable from wild type)." [PMID:22144463, PomBase:mah] synonym: "normal histone H3 K9 dimethylation at heterochromatin island during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at heterochromatin island during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal histone H3K9 dimethylation at heterochromatin island during vegetative growth" EXACT [PomBase:mah] synonym: "normal histone H3K9me2 at heterochromatin island during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T11:52:32Z" xsd:dateTime [Term] id: FYPO:0007530 name: abolished histone H3-K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 does not occur at heterochromatin islands near genes that are normally expressed during the meiotic cell cycle." [PMID:22144463, PomBase:mah] synonym: "abolished histone H3 K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at heterochromatin island at meiosis gene during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3-K9 dimethylation at heterochromatin island at meiotic gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone H3K9me2 at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation abolished at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002566 ! abolished histone H3-K9 methylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T12:07:50Z" xsd:dateTime [Term] id: FYPO:0007531 name: decreased histone H3-K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 is decreased at heterochromatin islands near genes that are normally expressed during the meiotic cell cycle." [PMID:22144463, PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at heterochromatin island at meiosis gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at heterochromatin island at meiotic gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9me2 at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007213 ! decreased histone H3-K9 dimethylation at heterochromatin island during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T12:20:52Z" xsd:dateTime [Term] id: FYPO:0007532 name: decreased replication fork colocalization with nuclear pore complex def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which arrested replication forks do not colocalize with nuclear pore complexes (NPCs) longer than actively replicating forks. Normally, arrested replication forks relocate to NPCs as part of replication fork processing, and remain anchored at NPCs while recombination-dependent replication takes place." [PMID:33159083, PomBase:mah] synonym: "decreased replication fork colocalization with NPC" EXACT [PomBase:mah] synonym: "decreased replication fork colocalization with nuclear pore" EXACT [PomBase:mah] synonym: "decreased replication fork colocalization with nuclear pore complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased replication fork colocalization with nuclear pore complex during mitotic S phase" EXACT [PomBase:mah] synonym: "decreased replication fork colocalization with nuclear pore complex during vegetative growth" EXACT [PomBase:mah] synonym: "decreased replication fork relocation to nuclear pore complex" EXACT [PMID:33159083] synonym: "decreased replication fork relocation to nuclear pore complex during mitotic S phase" EXACT [PMID:33159083] synonym: "reduced replication fork colocalization with nuclear pore complex" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T14:48:54Z" xsd:dateTime [Term] id: FYPO:0007533 name: normal replication fork colocalization with nuclear pore complex def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which arrested replication forks colocalize normally (i.e. indistinguishably from wild type) with nuclear pore complexes (NPCs). Normally, arrested replication forks relocate to NPCs as part of replication fork processing, and remain anchored at NPCs while recombination-dependent replication takes place." [PMID:33159083, PomBase:mah] synonym: "normal replication fork colocalization with NPC" EXACT [PomBase:mah] synonym: "normal replication fork colocalization with nuclear pore" EXACT [PomBase:mah] synonym: "normal replication fork colocalization with nuclear pore complex during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal replication fork colocalization with nuclear pore complex during mitotic S phase" EXACT [PomBase:mah] synonym: "normal replication fork colocalization with nuclear pore complex during vegetative growth" EXACT [PomBase:mah] synonym: "normal replication fork relocation to nuclear pore complex" EXACT [PMID:33159083] synonym: "normal replication fork relocation to nuclear pore complex during mitotic S phase" EXACT [PMID:33159083] is_a: FYPO:0007254 ! normal replication fork processing property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T15:01:02Z" xsd:dateTime [Term] id: FYPO:0007534 name: increased phosphorylation of RNA polymerase II C-terminal domain threonine 4 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the threonine residue at position 4 the C-terminal domain of RNA polymerase II occurs to a greater extent than normal." [PMID:30282034, PomBase:mah] synonym: "increased phosphorylation of RNA polymerase II C-terminal domain threonine 4 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased phosphorylation of RNA polymerase II CTD threonine 4 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T15:16:04Z" xsd:dateTime [Term] id: FYPO:0007535 name: normal phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type)." [PMID:30282034, PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II CTD serine 2 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T15:24:31Z" xsd:dateTime [Term] id: FYPO:0007536 name: normal protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type)." [PMID:30282034, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin at RNA polymerase II-transcribed genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at polymerase II transcribed genes during vegetative growth" EXACT [PomBase:vw] synonym: "normal protein localization to chromatin at RNA polymerase II-regulated genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at RNA polymerase II-transcribed genes during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-25T15:26:30Z" xsd:dateTime [Term] id: FYPO:0007537 name: increased replication slippage during replication fork processing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications (\"replication slippage\") that normally results from processing arrested replication forks is enhanced." [PMID:33159083, PomBase:mah] synonym: "increased replication slippage during replication fork processing during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased replication slippage during replication fork processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003586 ! abnormal replication fork processing property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-26T14:52:36Z" xsd:dateTime [Term] id: FYPO:0007538 name: sensitive to paromomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to paromomycin. Cells stop growing (and may die) at a concentration of paromomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to paromomycin" EXACT [PomBase:mah] synonym: "sensitive to paromomycin during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to paromomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-26T14:59:48Z" xsd:dateTime [Term] id: FYPO:0007539 name: normal phosphorylation of RNA polymerase II C-terminal domain threonine 4 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the threonine residue at position 4 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type)." [PMID:30282034, PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II C-terminal domain threonine 4 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II CTD threonine 4 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-30T12:02:20Z" xsd:dateTime [Term] id: FYPO:0007540 name: normal phosphorylation of RNA polymerase II C-terminal domain tyrosine 1 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the tyrosine residue at position 1 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type)." [PMID:30282034, PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II C-terminal domain tyrosine 1 residues during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal phosphorylation of RNA polymerase II CTD tyrosine 1 residues during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-30T12:06:23Z" xsd:dateTime [Term] id: FYPO:0007541 name: viable branched, swollen, elongated, multinucleate, multiseptate vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, has more than one nucleus and more than one septum, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PomBase:mah, PomBase:vw] synonym: "viable branched, elongated, swollen, multinucleate, multiseptate vegetative cell" EXACT [PomBase:vw] synonym: "viable branched, swollen, elongated, multinucleate, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable branched, swollen, elongated, multinucleate, multiseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0001252 ! multinucleate multiseptate vegetative cell is_a: FYPO:0003500 ! viable branched, elongated, multiseptate vegetative cell is_a: FYPO:0006167 ! viable branched, swollen, elongated, multinucleate vegetative cell is_a: FYPO:0007436 ! swollen elongated multiseptate vegetative cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-11-30T12:10:37Z" xsd:dateTime [Term] id: FYPO:0007542 name: normal double-stranded DNA binding def: "A molecular function phenotype in which occurrence of double-stranded DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "normal dsDNA binding" EXACT [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T12:19:47Z" xsd:dateTime [Term] id: FYPO:0007543 name: abolished double-stranded DNA binding def: "A molecular function phenotype in which double-stranded DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "abolished dsDNA binding" EXACT [PomBase:mah] synonym: "double-stranded DNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T13:46:28Z" xsd:dateTime [Term] id: FYPO:0007544 name: normal cohesin complex binding def: "A molecular function phenotype in which the binding of one protein to a cohesin complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the cohesin complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene." [PMID:33176147, PomBase:mah] is_a: FYPO:0005232 ! normal protein complex binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T13:49:46Z" xsd:dateTime [Term] id: FYPO:0007545 name: increased duration of protein localization to mitotic nuclear bridge def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic nuclear bridge for a longer time than normal." [PMID:32502403, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to mitotic nuclear bridge" EXACT [PomBase:mah] synonym: "increased duration of protein localization to mitotic nuclear bridge during mitotic anaphase B" EXACT [PomBase:vw] synonym: "increased duration of protein localization to mitotic nuclear bridge during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of protein localization to mitotic nuclear bridge during vegetative growth" EXACT [PomBase:mah] synonym: "prolonged protein localization to mitotic nuclear bridge" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:01:09Z" xsd:dateTime [Term] id: FYPO:0007546 name: abolished nuclear envelope division def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope division does not occur. Nuclear envelope division takes place at the end of mitosis; the nuclear envelope undergoes localized breakdown in the nuclear bridge midzone and the ends are sealed and retrieved into the envelopes of the separated daughter nuclei. When nuclear envelope division does not occur, the two DNA masses remain linked by the nuclear bridge, and may coalesce back into a single nucleus." [PMID:32502403, PMID:32848252, PomBase:mah, PomBase:vw] synonym: "abolished NE division" EXACT [PomBase:mah] synonym: "abolished nuclear envelope division during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished nuclear envelope division during vegetative growth" EXACT [PomBase:mah] synonym: "failed nuclear envelope division" EXACT [PMID:32502403] synonym: "nuclear envelope division abolished" EXACT [PomBase:mah] is_a: FYPO:0000815 ! abnormal nuclear envelope organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:09:34Z" xsd:dateTime [Term] id: FYPO:0007547 name: abnormal nuclear pore localization to mitotic nuclear bridge midzone membrane def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization to the portion of the nuclear envelope enclosing the mitotic nuclear bridge is abnormal, resulting in an abnormal distribution of nuclear pores in the bridge envelope. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase. Normally, nuclear pores that lack baskets are found in the midzone of the nuclear bridge." [PMID:32502403, PomBase:mah] synonym: "abnormal distribution of nuclear pores at nuclear bridge midzone membrane domain" EXACT [PomBase:vw] synonym: "abnormal NPC localization to mitotic nuclear bridge midzone membrane" EXACT [PomBase:mah] synonym: "abnormal nuclear pore complex localization to mitotic nuclear bridge midzone membrane" EXACT [PomBase:mah] synonym: "abnormal nuclear pore distribution in mitotic nuclear bridge midzone membrane" EXACT [PomBase:mah] synonym: "abnormal nuclear pore distribution in mitotic nuclear bridge midzone membrane domain" EXACT [PomBase:mah] synonym: "abnormal nuclear pore localization to mitotic nuclear bridge midzone membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nuclear pore localization to mitotic nuclear bridge midzone membrane during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003783 ! abnormal nuclear pore localization during mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:12:35Z" xsd:dateTime [Term] id: FYPO:0007548 name: abnormal mitotic nuclear bridge midzone membrane domain organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope organization is abnormal in the region of the nuclear envelope that surrounds the mitotic nuclear bridge during mitosis." [PMID:32502403, PomBase:mah] synonym: "abnormal mitotic nuclear bridge midzone envelope organization" EXACT [PomBase:mah] synonym: "abnormal mitotic nuclear bridge midzone membrane domain organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal mitotic nuclear bridge midzone membrane domain organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal MMD organization" EXACT [PMID:32502403, PomBase:vw] synonym: "abnormal nuclear bridge midzone membrane domain organization" EXACT [PomBase:vw] synonym: "abnormal nuclear envelope organization at mitotic nuclear bridge midzone" EXACT [PomBase:mah] is_a: FYPO:0000815 ! abnormal nuclear envelope organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:18:17Z" xsd:dateTime [Term] id: FYPO:0007549 name: coalescence of partially separated nuclei def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the two DNA masses separated by mitotic anaphase remain linked by the nuclear bridge, and then merge back into a single nucleus." [PMID:32502403, PomBase:mah] synonym: "coalescence of partially separated nuclei during mitotic cell cycle" RELATED [PomBase:mah] synonym: "coalescence of partially separated nuclei during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: part_of FYPO:0000337 ! abnormal mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:23:02Z" xsd:dateTime [Term] id: FYPO:0007550 name: increased number of Rad52 foci during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to hydroxyurea." [PMID:19158664, PomBase:mah] synonym: "increased number of Rad22 foci during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to HU" EXACT [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased number of Rad52 foci during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000972 ! increased number of Rad52 foci during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:30:57Z" xsd:dateTime [Term] id: FYPO:0007551 name: increased protein localization to chromatin during cellular response to hydroxyurea def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during a cellular response to hydroxyurea." [PMID:19158664, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to chromatin during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to HU" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003011 ! increased protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:35:13Z" xsd:dateTime [Term] id: FYPO:0007552 name: normal protein ubiquitination during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein ubiquitination during cellular response to HU" EXACT [PomBase:mah] synonym: "normal protein ubiquitination during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein ubiquitination during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein ubiquitinylation during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal protein ubiquitylation during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "normal protein/peptide ubiquitination during cellular response to hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0002635 ! normal protein ubiquitination during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-09T15:37:34Z" xsd:dateTime [Term] id: FYPO:0007553 name: normal G1 to G0 transition def: "A cellular process phenotype in which the G1 to G0 transition is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell cycle quiescence" RELATED [GO:0070314, PomBase:mah] synonym: "normal establishment of cell quiescence" EXACT [GO:0070314, PomBase:mah] synonym: "normal G1/G0 transition" EXACT [GO:0070314, PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T11:58:48Z" xsd:dateTime [Term] id: FYPO:0007554 name: sensitive to tolnaftate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tolnaftate. Cells stop growing (and may die) at a concentration of tolnaftate that allows wild type cells to grow." [PMID:33223513, PomBase:mah] synonym: "hypersensitive to tolnaftate" EXACT [PomBase:mah] synonym: "sensitive to TFT" EXACT [PMID:33223513] synonym: "sensitive to tolnaftate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to tolnaftate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T12:16:53Z" xsd:dateTime [Term] id: FYPO:0007555 name: sensitive to econazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to econazole. Cells stop growing (and may die) at a concentration of econazole that allows wild type cells to grow." [PMID:33223513, PomBase:mah] synonym: "hypersensitive to econazole" EXACT [PomBase:mah] synonym: "sensitive to econazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to econazole during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ECZ" EXACT [PMID:33223513] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T14:19:55Z" xsd:dateTime [Term] id: FYPO:0007556 name: sensitive to diethylstilbestrol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to diethylstilbestrol. Cells stop growing (and may die) at a concentration of diethylstilbestrol that allows wild type cells to grow." [PMID:33223513, PomBase:mah] synonym: "hypersensitive to diethylstilbestrol" EXACT [PomBase:mah] synonym: "sensitive to DES" EXACT [PMID:33223513] synonym: "sensitive to diethylstilbestrol during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to diethylstilbestrol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T14:30:27Z" xsd:dateTime [Term] id: FYPO:0007557 name: normal growth on tolnaftate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tolnaftate." [PMID:33223513, PomBase:mah] synonym: "normal cell population growth in presence of tolnaftate" EXACT [PomBase:mah] synonym: "normal cell population growth on TFT" EXACT [PMID:33223513] synonym: "normal cell population growth on tolnaftate" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to tolnaftate" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on tolnaftate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T14:31:22Z" xsd:dateTime [Term] id: FYPO:0007558 name: normal growth on econazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing econazole." [PMID:33223513, PomBase:mah] synonym: "normal cell population growth in presence of econazole" EXACT [PomBase:mah] synonym: "normal cell population growth on econazole" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cell population growth on ECZ" EXACT [PMID:33223513] synonym: "normal cellular response to econazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on econazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T14:32:10Z" xsd:dateTime [Term] id: FYPO:0007559 name: normal growth on diethylstilbestrol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing diethylstilbestrol." [PMID:33223513, PomBase:mah] synonym: "normal cell population growth in presence of diethylstilbestrol" EXACT [PomBase:mah] synonym: "normal cell population growth on DES" EXACT [PMID:33223513] synonym: "normal cell population growth on diethylstilbestrol" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal cellular response to diethylstilbestrol" RELATED [PomBase:al, PomBase:mah] synonym: "normal vegetative cell population growth on diethylstilbestrol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T14:32:51Z" xsd:dateTime [Term] id: FYPO:0007560 name: sensitive to arginine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-arginine. Cells stop growing (and may die) at a concentration of L-arginine that allows wild type cells to grow." [PMID:32896087, PomBase:mah] synonym: "decreased cell population growth in presence of arginine" EXACT [PMID:32896087] synonym: "hypersensitive to arginine" EXACT [PomBase:mah] synonym: "sensitive to arginine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to arginine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to L-arginine" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-11T15:45:03Z" xsd:dateTime [Term] id: FYPO:0007561 name: sensitive to chaetoglobosin D def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chaetoglobosin D. Cells stop growing (and may die) at a concentration of chaetoglobosin D that allows wild type cells to grow." [PMID:32313168, PomBase:mah] synonym: "hypersensitive to chaetoglobosin D" EXACT [PomBase:mah] synonym: "sensitive to chaetoglobosin D during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to chaetoglobosin D during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-15T12:58:17Z" xsd:dateTime [Term] id: FYPO:0007562 name: decreased cell population growth on serine nitrogen source def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing serine as the nitrogen source." [PMID:32313168, PomBase:mah] synonym: "decreased growth on serine nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on serine nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth with serine nitrogen source" NARROW [PomBase:mah] synonym: "reduced cell population growth on serine nitrogen source" EXACT [PomBase:mah] synonym: "slow cell growth on serine nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-15T13:00:27Z" xsd:dateTime [Term] id: FYPO:0007563 name: cell cycle arrest in mitotic G1 phase in response to pheromone without starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to a pheromone occurs in G1 phase, but in the absence of starvation (i.e., in nutrient-rich conditions, under which wild-type fission yeast cells do not arrest)." [PMID:11554925, PomBase:al, PomBase:mah] synonym: "cell cycle arrest in mitotic G1 phase in response to pheromone in absence of starvation" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in response to pheromone in absence of starvation" BROAD [PomBase:al] synonym: "pheromone-induced mitotic cell cycle arrest in mitotic G1 phase without starvation" EXACT [PomBase:mah] is_a: FYPO:0000530 ! abnormal mitotic cell cycle arrest in response to pheromone property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-15T13:03:15Z" xsd:dateTime [Term] id: FYPO:0007564 name: normal DNA binding at MCB def: "A molecular function phenotype in which occurrence of DNA binding at a Mlu1 cell cycle box (MCB) by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene." [PMID:8223442, PomBase:mah] synonym: "normal DNA binding at Mlu1 cell cycle box" EXACT [SO:0001855] synonym: "normal MCB DNA binding" EXACT [PomBase:mah] synonym: "normal RNA polymerase II proximal promoter sequence-specific DNA binding at MCB" EXACT [GO:0000978] synonym: "normal RNA polymerase II proximal promoter sequence-specific DNA binding at Mlu1 cell cycle box" EXACT [GO:0000978, SO:0001855] is_a: FYPO:0000655 ! normal DNA binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-17T13:50:51Z" xsd:dateTime [Term] id: FYPO:0007565 name: abolished DNA binding at MCB def: "A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter that contains a Mlu1 cell cycle box (MCB) by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:8223442, PomBase:mah] synonym: "abolished DNA binding at Mlu1 cell cycle box" EXACT [SO:0001855] synonym: "abolished RNA polymerase II proximal promoter sequence-specific DNA binding at MCB" EXACT [GO:0000978] synonym: "abolished RNA polymerase II proximal promoter sequence-specific DNA binding at Mlu1 cell cycle box" EXACT [GO:0000978, SO:0001855] synonym: "RNA polymerase II proximal promoter sequence-specific DNA binding abolished at MCB" EXACT [PomBase:mah] is_a: FYPO:0002003 ! abolished RNA polymerase II proximal promoter sequence-specific DNA binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2020-12-17T13:55:30Z" xsd:dateTime [Term] id: FYPO:0007566 name: premature mitotic chromosome condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation begins earlier than normal." [PMID:11927555, PomBase:mah] synonym: "advanced mitotic chromosome condensation" EXACT [PomBase:mah] synonym: "premature chromosome condensation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000214 ! abnormal mitotic chromosome condensation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T11:13:59Z" xsd:dateTime [Term] id: FYPO:0007567 name: premature protein localization to mitotic spindle pole body during metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body that normally occurs in anaphase instead begins in metaphase of the mitotic cell cycle." [PMID:10775265, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to mitotic spindle pole body during metaphase" EXACT [PomBase:mah] synonym: "premature protein localisation to mitotic spindle pole body during metaphase" EXACT [PomBase:mah] synonym: "premature protein localization to mitotic spindle pole body during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "premature protein localization to spindle pole body during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature protein localization to spindle pole body during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0006824 ! premature protein localization to mitotic spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T11:36:18Z" xsd:dateTime [Term] id: FYPO:0007568 name: normal protein localization to mitotic spindle pole body during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during anaphase." [PMID:11384993, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to mitotic spindle pole body during anaphase" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle pole body during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to mitotic spindle pole body during anaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole body during mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0005709 ! normal protein localization to mitotic spindle pole body during mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T11:50:20Z" xsd:dateTime [Term] id: FYPO:0007569 name: abnormal septation initiation network signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling is abnormal SIN signaling is mediated by the small GTPase Ras, and results in the initiation of contraction of the contractile ring at the beginning of cytokinesis and cell division by septum formation." [GO:0031028, PomBase:mah] synonym: "abnormal septation initiation network signaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal septation initiation network signaling during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal septation initiation network signalling" EXACT [PomBase:mah] synonym: "abnormal septation initiation signaling" EXACT [GO:0031028] synonym: "abnormal SIN signaling" EXACT [PomBase:mah] synonym: "abnormal SIN signalling" EXACT [PomBase:mah] synonym: "septation initiation defective" EXACT [] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T12:02:31Z" xsd:dateTime [Term] id: FYPO:0007570 name: septation initiation network signaling from both mitotic spindle pole bodies def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling takes place at both mitotic spindle pole bodies. Normally, SIN signaling occurs only at the new SPB." [PMID:15132994, PomBase:mah] synonym: "abnormal septation initiation network signaling from both mitotic spindle pole bodies" EXACT [PomBase:mah] synonym: "septation initiation network signaling from both mitotic SPBs" EXACT [PomBase:mah] synonym: "septation initiation network signaling from both mitotic spindle pole bodies during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septation initiation network signaling from both mitotic spindle pole bodies during vegetative growth" EXACT [PomBase:mah] synonym: "septation initiation network signaling from old and new mitotic SPBs" EXACT [PomBase:vw] synonym: "septation initiation network signaling from old and new mitotic spindle pole bodies" EXACT [PomBase:vw] synonym: "septation initiation network signalling from both mitotic spindle pole bodies" EXACT [PomBase:mah] synonym: "septation initiation signaling from both mitotic spindle pole bodies" EXACT [GO:0031028] synonym: "SIN signaling from both mitotic SPBs" EXACT [PomBase:mah] synonym: "SIN signaling from both mitotic spindle pole bodies" EXACT [PomBase:mah] is_a: FYPO:0007569 ! abnormal septation initiation network signaling property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T13:51:10Z" xsd:dateTime [Term] id: FYPO:0007571 name: abnormal cortical endoplasmic reticulum organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cortical endoplasmic reticulum (ER) organization is abnormal. Cortical ER organization results in the assembly, arrangement of constituent parts, or disassembly of the part of the endoplasmic reticulum that consists of highly dynamic tubules that are juxtaposed to the plasma membrane." [GO:0007029, GO:0032541, PMID:19571115, PomBase:mah] synonym: "abnormal cortical endoplasmic reticulum organisation" EXACT [PomBase:mah] synonym: "abnormal cortical endoplasmic reticulum organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal cortical endoplasmic reticulum organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cortical ER organization" EXACT [PomBase:mah] is_a: FYPO:0000805 ! abnormal endoplasmic reticulum organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T14:22:27Z" xsd:dateTime [Term] id: FYPO:0007572 name: cortical endoplasmic reticulum detached from plasma membrane def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cortical endoplasmic reticulum (ER) is dissociated from the plasma membrane. Normally, cortical ER tubules are closely juxtaposed to the plasma membrane." [PMID:19571115, PomBase:mah] synonym: "cortical endoplasmic reticulum detached from plasma membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "cortical endoplasmic reticulum detached from plasma membrane during vegetative growth" EXACT [PomBase:mah] synonym: "cortical endoplasmic reticulum dissociated from plasma membrane" EXACT [PomBase:mah] synonym: "cortical ER detached from plasma membrane" EXACT [PomBase:mah] is_a: FYPO:0000354 ! abnormal endoplasmic reticulum morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T14:33:18Z" xsd:dateTime [Term] id: FYPO:0007573 name: premature actomyosin contractile ring contraction with increased contraction rate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins earlier than normal and the rate, or speed, of ring contraction is increased." [PMID:25451933, PomBase:mah, PomBase:vw] synonym: "advanced actomyosin contractile ring contraction with increased contraction rate" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring constriction with increased constriction rate" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring constriction with increased rate of contraction" EXACT [PomBase:vw] synonym: "premature actomyosin contractile ring contraction with increased contraction rate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature actomyosin contractile ring contraction with increased contraction rate during vegetative growth" EXACT [PomBase:mah] synonym: "premature contractile ring contraction with increased rate of contraction" EXACT [PomBase:vw] synonym: "premature cytokinetic contractile ring contraction with increased rate of contraction" EXACT [PomBase:vw] synonym: "premature mitotic actomyosin contractile ring contraction with increased contraction rate" EXACT [PomBase:mah] synonym: "premature, fast actomyosin contractile ring contraction" EXACT [PomBase:mah] is_a: FYPO:0004430 ! premature actomyosin contractile ring contraction is_a: FYPO:0006897 ! increased rate of actomyosin contractile ring contraction relationship: has_part FYPO:0004430 ! premature actomyosin contractile ring contraction relationship: has_part FYPO:0006897 ! increased rate of actomyosin contractile ring contraction property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T15:10:35Z" xsd:dateTime [Term] id: FYPO:0007574 name: decreased duration of protein localization to mitotic spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle pole body for a shorter time than normal." [PMID:25501814, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased duration of protein localisation to mitotic spindle pole body" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to mitotic SPB" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to mitotic spindle pole body during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "reduced duration protein localization to mitotic spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to mitotic spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T15:28:37Z" xsd:dateTime [Term] id: FYPO:0007575 name: decreased duration of protein localization to medial cortical node def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the medial cortical nodes for a shorter time than normal." [PMID:25501814, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased duration of protein localisation to cytokinetic nodes" EXACT [PomBase:mah] synonym: "decreased duration of protein localisation to medial cortical dot" EXACT [PomBase:vw] synonym: "decreased duration of protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased duration of protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "decreased duration of protein localization to medial cortical nodes" EXACT [PomBase:mah] synonym: "decreased duration of protein recruitment to medial cortical node" RELATED [PomBase:vw] synonym: "reduced duration protein localization to medial cortical node" EXACT [PomBase:mah] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-06T15:30:23Z" xsd:dateTime [Term] id: FYPO:0007576 name: abnormal vacuole fission def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fission, i.e. the division of one vacuole into two or more separate vacuoles, is abnormal." [GO:0140572, PomBase:mah] synonym: "abnormal vacuole division" EXACT [PomBase:mah] synonym: "abnormal vacuole fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal vacuole fission during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000812 ! abnormal vacuole organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T10:41:55Z" xsd:dateTime [Term] id: FYPO:0007577 name: abnormal protein localization to actin cytoskeleton def: "A cell phenotype in which the localization of a protein to the actin cytoskeleton is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actin cytoskeleton" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T11:19:05Z" xsd:dateTime [Term] id: FYPO:0007578 name: abnormal protein localization to actin cytoskeleton during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actin cytoskeleton is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actin cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to actin cytoskeleton during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0007577 ! abnormal protein localization to actin cytoskeleton property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T11:21:26Z" xsd:dateTime [Term] id: FYPO:0007579 name: normal medial membrane band sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the medial membrane band is normal (i.e. indistinguishable from wild type)." [GO:0032178, PMID:15517003, PomBase:mah] synonym: "normal medial membrane band sterol distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal medial membrane band sterol distribution during vegetative growth" EXACT [PomBase:mah] synonym: "normal medial membrane domain sterol distribution" EXACT [PomBase:vw] is_a: FYPO:0004963 ! normal plasma membrane sterol distribution property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T12:01:43Z" xsd:dateTime [Term] id: FYPO:0007580 name: decreased protein localization to mitotic spindle pole body during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during anaphase B of mitosis." [PMID:19736319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle pole body during anaphase B" EXACT [PomBase:mah] synonym: "decreased protein localization to mitotic SPB during anaphase B" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during mitotic anaphase B" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle pole body during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0005211 ! decreased protein localization to mitotic spindle pole body during anaphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T12:45:55Z" xsd:dateTime [Term] id: FYPO:0007581 name: decreased septation initiation network signaling during anaphase B def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling occurs to a lower extent than normal during anaphase B of the mitotic cell cycle." [PMID:19736319, PomBase:mah] synonym: "decreased septation initiation network signaling during mitotic anaphase B" EXACT [PomBase:mah] synonym: "decreased septation initiation network signalling during anaphase B" EXACT [PomBase:mah] synonym: "decreased septation initiation signaling during anaphase B" EXACT [GO:0031028] synonym: "decreased SIN signaling during anaphase B" EXACT [PomBase:mah] synonym: "reduced septation initiation network signaling during anaphase B" EXACT [PomBase:mah] is_a: FYPO:0007569 ! abnormal septation initiation network signaling property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T15:01:02Z" xsd:dateTime [Term] id: FYPO:0007582 name: increased duration of septation initiation network signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septation initiation network signaling is longer than normal. Signaling may continue after cytokinesis takes place." [PMID:19736319, PomBase:mah, PomBase:vw] synonym: "increased duration of septation initiation network signaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of septation initiation network signaling during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of septation initiation network signalling" EXACT [PomBase:mah] synonym: "increased duration of septation initiation signaling" EXACT [GO:0031028] synonym: "increased duration of SIN signaling" EXACT [PomBase:mah] synonym: "prolonged septation initiation network signaling" EXACT [PomBase:mah] is_a: FYPO:0007569 ! abnormal septation initiation network signaling property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T15:58:41Z" xsd:dateTime [Term] id: FYPO:0007583 name: decreased protein localization to cytoplasm during mitotic telophase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased during telophase of mitosis." [PMID:19736319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cytoplasm during mitotic telophase" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasm during telophase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cytoplasm during telophase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein localization to cytoplasm during mitotic telophase" EXACT [PomBase:mah] is_a: FYPO:0006099 ! decreased protein localization to cytoplasm property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T16:15:00Z" xsd:dateTime [Term] id: FYPO:0007584 name: multiseptate vegetative cell with normal cell length def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cell length is normal, and the cell contains more than one septum." [PMID:19736319, PomBase:mah] synonym: "multiseptate cell with normal cell length during vegetative growth" EXACT [PomBase:mah] synonym: "multiseptate vegetative cell with normal cell length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "multiseptate vegetative cell with normal length" EXACT [PomBase:mah] synonym: "normal length multiseptate vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000118 ! multiseptate vegetative cell is_a: FYPO:0003503 ! normal vegetative cell length property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T16:27:58Z" xsd:dateTime [Term] id: FYPO:0007585 name: premature septation initiation network signaling def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling begins earlier than normal. Signaling may begin in interphase of the mitotic cell cycle." [PMID:19736319, PomBase:mah, PomBase:vw] synonym: "advanced septation initiation network signaling" EXACT [PomBase:mah] synonym: "premature septation initiation network signaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature septation initiation network signaling during vegetative growth" EXACT [PomBase:mah] synonym: "premature septation initiation network signalling" EXACT [PomBase:mah] synonym: "premature septation initiation signaling" EXACT [GO:0031028] synonym: "premature SIN signaling" EXACT [PomBase:mah] is_a: FYPO:0007569 ! abnormal septation initiation network signaling property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-07T16:45:08Z" xsd:dateTime [Term] id: FYPO:0007586 name: abnormal medial membrane band sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the medial membrane band is abnormal." [GO:0032178, PMID:15517003, PomBase:mah] synonym: "abnormal medial membrane band sterol distribution during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal medial membrane band sterol distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal medial membrane domain sterol distribution" EXACT [PomBase:vw] is_a: FYPO:0000135 ! abnormal plasma membrane sterol distribution property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T11:36:29Z" xsd:dateTime [Term] id: FYPO:0007587 name: abnormal protein localization to endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endosome(s) is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to endosome" EXACT [PomBase:mah] synonym: "abnormal protein localization to endosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to endosome during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein targeting to endosome" RELATED [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T12:10:04Z" xsd:dateTime [Term] id: FYPO:0007588 name: abolished protein localization to late endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes does not occur." [PMID:19624755, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to late endosome" EXACT [PomBase:mah] synonym: "abolished protein localization to late endosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to late endosome during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to prevacuolar compartment" EXACT [GO:0005770] synonym: "abolished protein localization to prevacuolar endosome" EXACT [PomBase:vw] synonym: "abolished protein localization to PVE" EXACT [PomBase:vw] synonym: "protein localization to late endosome abolished" EXACT [PomBase:mah] is_a: FYPO:0007587 ! abnormal protein localization to endosome property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T12:25:38Z" xsd:dateTime [Term] id: FYPO:0007589 name: protein mislocalized to endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in endosomes is observed there." [PMID:19624755, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to endosome" EXACT [PomBase:vw] synonym: "protein mislocalised to endosome" EXACT [PomBase:mah] synonym: "protein mislocalized to endosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein mislocalized to endosome during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T12:30:27Z" xsd:dateTime [Term] id: FYPO:0007590 name: abnormal mitophagy def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is abnormal." [GO:0000422, PomBase:mah] synonym: "abnormal autophagy of mitochondrion" EXACT [GO:0000422] is_a: FYPO:0008082 ! abnormal autophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T14:03:22Z" xsd:dateTime [Term] id: FYPO:0007591 name: normal mitophagy def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is normal (i.e. indistinguishable from wild type)." [GO:0000422, PomBase:mah] synonym: "normal autophagy of mitochondrion" EXACT [GO:0000422] is_a: FYPO:0000627 ! normal cellular process property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T15:09:16Z" xsd:dateTime [Term] id: FYPO:0007592 name: normal mitophagy during nitrogen starvation def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "normal autophagy of mitochondrion during nitrogen depletion" EXACT [PomBase:vw] synonym: "normal autophagy of mitochondrion during nitrogen deprivation" EXACT [PomBase:vw] synonym: "normal autophagy of mitochondrion during nitrogen starvation" EXACT [GO:0000422] is_a: FYPO:0007591 ! normal mitophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T15:30:10Z" xsd:dateTime [Term] id: FYPO:0007593 name: abnormal mitophagy during nitrogen starvation def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "abnormal autophagy of mitochondrion during nitrogen depletion" EXACT [PomBase:vw] synonym: "abnormal autophagy of mitochondrion during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abnormal autophagy of mitochondrion during nitrogen starvation" EXACT [GO:0000422] is_a: FYPO:0007590 ! abnormal mitophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T15:34:25Z" xsd:dateTime [Term] id: FYPO:0007594 name: abolished mitophagy during nitrogen starvation def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, does not occur when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "abolished autophagy of mitochondrion during nitrogen depletion" EXACT [PomBase:vw] synonym: "abolished autophagy of mitochondrion during nitrogen deprivation" EXACT [PomBase:vw] synonym: "abolished autophagy of mitochondrion during nitrogen starvation" EXACT [GO:0000422] synonym: "autophagy of mitochondrion abolished during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000499 ! abolished mitophagy is_a: FYPO:0007593 ! abnormal mitophagy during nitrogen starvation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T15:35:39Z" xsd:dateTime [Term] id: FYPO:0007595 name: increased mitophagy during nitrogen starvation def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is increased when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "increased autophagy of mitochondrion during nitrogen depletion" EXACT [PomBase:vw] synonym: "increased autophagy of mitochondrion during nitrogen deprivation" EXACT [PomBase:vw] synonym: "increased autophagy of mitochondrion during nitrogen starvation" EXACT [GO:0000422] is_a: FYPO:0000501 ! increased mitophagy is_a: FYPO:0007593 ! abnormal mitophagy during nitrogen starvation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T15:35:53Z" xsd:dateTime [Term] id: FYPO:0007596 name: decreased mitophagy during nitrogen starvation def: "A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is decreased when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased autophagy of mitochondrion during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased autophagy of mitochondrion during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased autophagy of mitochondrion during nitrogen starvation" EXACT [GO:0000422] synonym: "reduced autophagy of mitochondrion during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000500 ! decreased mitophagy is_a: FYPO:0007593 ! abnormal mitophagy during nitrogen starvation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T15:36:04Z" xsd:dateTime [Term] id: FYPO:0007597 name: abolished CLRC complex binding def: "A molecular function phenotype in which CLRC complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:23613586, PomBase:mah] synonym: "abolished CLRC ubiquitin ligase complex binding" EXACT [GO:0043494] synonym: "CLRC binding complex abolished" EXACT [PomBase:mah] is_a: FYPO:0003591 ! abnormal protein complex binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T16:03:22Z" xsd:dateTime [Term] id: FYPO:0007598 name: abolished chromatin silencing at ectopic tethering site def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at a site where silencing can normally be triggered by the ectopic tethering of a protein." [PMID:23613586, PomBase:mah] comment: Note that this term incorporates some information about experimental tools, but is included to allow effects of tethering different (wild-type or mutated) proteins to the binding site to be represented. The tethering site is placed adjacent to a reporter gene that is expressed in the absence of a binding domain fusion (i.e. in a region not normally silenced). synonym: "abolished chromatin silencing at ectopic tethering site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished chromatin silencing at ectopic tethering site during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T16:28:17Z" xsd:dateTime [Term] id: FYPO:0007599 name: increased chromatin silencing at ectopic tethering site def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is increased at a site where silencing can be triggered by the ectopic tethering of a protein." [PMID:23613586, PomBase:mah] comment: Note that this term incorporates some information about experimental tools, but is included to allow effects of tethering different (wild-type or mutated) proteins to the binding site to be represented. The tethering site is placed adjacent to a reporter gene that is expressed in the absence of a binding domain fusion (i.e. in a region not normally silenced). synonym: "increased chromatin silencing at ectopic tethering site" RELATED [PomBase:mah] synonym: "increased chromatin silencing at ectopic tethering site during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T16:30:07Z" xsd:dateTime [Term] id: FYPO:0007600 name: decreased protein localization to mitochondrial outer membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrial outer membrane is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitochondrial outer membrane" EXACT [PomBase:mah] synonym: "decreased protein localization to mitochondrial outer membrane during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to mitochondrial outer membrane during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to mitochondrion outer membrane" EXACT [PomBase:vw] synonym: "reduced protein localization to mitochondrial outer membrane" EXACT [PomBase:mah] is_a: FYPO:0004336 ! abnormal protein localization to mitochondrion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T16:47:13Z" xsd:dateTime [Term] id: FYPO:0007601 name: decreased protein localization to mitochondrion, with diffuse cytoplasmic protein mislocalization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is decreased, and the protein is instead visible diffusely localized in the cytoplasm." [PMID:33138913, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitochondrion, with diffuse cytoplasmic protein mislocalisation" EXACT [PomBase:mah] synonym: "decreased protein localization to mitochondrion, with diffuse cytoplasmic localization" EXACT [PomBase:vw] synonym: "decreased protein localization to mitochondrion, with diffuse cytoplasmic protein mislocalization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to mitochondrion, with diffuse cytoplasmic protein mislocalization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to mitochondrion, with diffuse cytoplasmic protein mislocalization" EXACT [PomBase:mah] is_a: FYPO:0007038 ! decreased protein localization to mitochondrion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T16:48:00Z" xsd:dateTime [Term] id: FYPO:0007602 name: decreased cellular superoxide level during nitrogen starvation def: "A cell phenotype in which the amount of superoxide measured in a cell that is subject to nitrogen starvation is lower than normal." [PMID:33138913, PomBase:mah] synonym: "decreased cellular superoxide level during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased cellular superoxide level during nitrogen deprivation" EXACT [PomBase:vw] is_a: FYPO:0004139 ! altered level of substance in cell during nitrogen starvation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-12T16:56:06Z" xsd:dateTime [Term] id: FYPO:0007603 name: decreased microfilament motor activity def: "A molecular function phenotype in which the observed rate or other property of a microfilament motor activity is decreased." [PomBase:mah] synonym: "decreased actin filament motor activity" EXACT [GO:0000146] synonym: "decreased microfilament motor (ATPase) activity" EXACT [PomBase:vw] synonym: "decreased myosin ATPase activity" RELATED [GO:0000146] synonym: "reduced microfilament motor activity" EXACT [PomBase:mah] is_a: FYPO:0006093 ! abnormal microfilament motor activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T11:45:19Z" xsd:dateTime [Term] id: FYPO:0007604 name: smooth ascospore wall def: "A physical cellular phenotype in which the outer surface of the spore wall is smooth, lacking the structures than protrude outward from normal spore walls." [PMID:33202882, PomBase:mah] synonym: "smooth spore wall" EXACT [PomBase:mah] is_a: FYPO:0003138 ! abnormal ascospore wall morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T11:51:31Z" xsd:dateTime [Term] id: FYPO:0007605 name: decreased outer prospore membrane breakdown def: "A cellular process phenotype in which breakdown of the outer layer of the prospore membrane (forespore membrane; FSM) is decreased. Normally, the outer of the two FSM layers breaks down completely, producing a mature spore. When FSM breakdown does not occur normally, the outer FSM layers of two adjacent spores may be fused." [PMID:33202882, PomBase:mah] synonym: "decreased outer forespore membrane breakdown" EXACT [PomBase:mah] synonym: "decreased outer membrane FSM breakdown" EXACT [PomBase:mah] synonym: "decreased outer prospore membrane degradation" EXACT [PomBase:mah] synonym: "reduced outer prospore membrane breakdown" EXACT [PomBase:mah] is_a: FYPO:0000196 ! abnormal prospore formation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T11:54:12Z" xsd:dateTime [Term] id: FYPO:0007606 name: decreased DNA degradation during nitrogen starvation def: "A cellular process phenotype in which the breakdown of DNA occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased DNA catabolic process during nitrogen starvation" EXACT [GO:0006308] synonym: "decreased DNA catabolism during nitrogen starvation" EXACT [GO:0006308] synonym: "decreased DNA degradation during nitrogen depletion" EXACT [PomBase:mah] synonym: "decreased DNA degradation during nitrogen deprivation" EXACT [PomBase:mah] synonym: "reduced DNA degradation during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T13:19:38Z" xsd:dateTime [Term] id: FYPO:0007607 name: delayed onset of mitotic DNA replication initiation during recovery from nitrogen starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins later than normal when cells are returned to nitrogen-rich medium following nitrogen starvation." [PomBase:mah] synonym: "delayed mitotic DNA replication initiation during recovery from nitrogen starvation" EXACT [PomBase:mah] synonym: "delayed onset of mitotic DNA replication initiation during recovery from nitrogen depletion" EXACT [PomBase:mah] synonym: "delayed onset of mitotic DNA replication initiation during recovery from nitrogen deprivation" EXACT [PomBase:mah] is_a: FYPO:0006031 ! delayed onset of mitotic DNA replication initiation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T14:01:04Z" xsd:dateTime [Term] id: FYPO:0007608 name: abnormal RNA localization during meiotic cell cycle def: "A cell phenotype in which the localization of an RNA in a cell is abnormal during the meiotic cell cycle. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] synonym: "abnormal cellular RNA localization during meiotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal RNA localisation during meiotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0003057 ! abnormal RNA localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T14:20:29Z" xsd:dateTime [Term] id: FYPO:0007609 name: abolished tRNA guanosine 7-methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 7-methylguanosine does not occur." [http://modomics.genesilico.pl/modifications/m7G/, PMID:32841241, PomBase:mah] synonym: "abolished 7-methylguanosine level in tRNA" RELATED [PomBase:vw] synonym: "abolished tRNA 7-methylguanosine formation" EXACT [PomBase:mah] synonym: "abolished tRNA guanosine 7-methylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished tRNA guanosine 7-methylation during vegetative growth" EXACT [PomBase:mah] synonym: "abolished tRNA m7G formation" EXACT [http://modomics.genesilico.pl/modifications/m7G/] synonym: "tRNA guanosine 7-methylation abolished" EXACT [PomBase:mah] is_a: FYPO:0001766 ! abnormal tRNA methylation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T14:42:07Z" xsd:dateTime [Term] id: FYPO:0007610 name: decreased mitochondrial volume def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total volume of all mitochondria in the cell is lower than normal." [PomBase:mah] synonym: "decreased mitochondrial volume during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial volume during vegetative growth" EXACT [PomBase:mah] synonym: "decreased total mitochondrial volume" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T15:01:35Z" xsd:dateTime [Term] id: FYPO:0007611 name: small fragmented mitochondria present in decreased numbers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are smaller, and the total number of mitochondria in the cell is lower, than normal. Total mitochondrial volume is therefore lower than normal normal." [PMID:31562247, PomBase:mah] synonym: "small mitochondria with decreased mitochondrial volume during mitotic cell cycle" RELATED [PomBase:mah] synonym: "small mitochondria with decreased total mitochondrial volume during vegetative growth" EXACT [PomBase:mah] synonym: "small mitochondria with reduced mitochondrial volume" EXACT [PomBase:mah] is_a: FYPO:0007193 ! small fragmented mitochondria relationship: has_part FYPO:0007193 ! small fragmented mitochondria relationship: has_part FYPO:0007610 ! decreased mitochondrial volume property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T15:03:45Z" xsd:dateTime [Term] id: FYPO:0007612 name: increased transcription from STREP promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs occurs to a greater extent than normal." [PomBase:mah] synonym: "decreased transcription from STREP promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased transcription from STREP promoter during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription from STREP promoter" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T15:32:00Z" xsd:dateTime [Term] id: FYPO:0007613 name: decreased transcription from STREP promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs occurs to a lower extent than normal." [PomBase:mah] synonym: "increased transcription from STREP promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from STREP promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T15:34:10Z" xsd:dateTime [Term] id: FYPO:0007614 name: normal transcription from STREP promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc." [PomBase:mah] synonym: "normal transcription from STREP promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription from STREP promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001855 ! normal transcription during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T15:35:49Z" xsd:dateTime [Term] id: FYPO:0007615 name: increased transcription from STREP promoter during cellular response to nitric oxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs occurs to a greater extent than normal during a cellular response to nitric oxide." [PomBase:mah] synonym: "increased transcription from STREP promoter during cellular response to nitric oxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased transcription from STREP promoter during cellular response to nitric oxide during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription from STREP promoter during cellular response to NO" EXACT [PomBase:mah] is_a: FYPO:0002781 ! increased transcription during cellular response to nitric oxide is_a: FYPO:0007612 ! increased transcription from STREP promoter property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-20T15:57:05Z" xsd:dateTime [Term] id: FYPO:0007616 name: sensitive to diuron def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to diuron. Cells stop growing (and may die) at a concentration of diuron that allows wild type cells to grow." [PomBase:mah] synonym: "sensitive to 3-(3,4-dichlorophenyl)-1,1-dimethylurea" EXACT [CHEBI:116509] synonym: "sensitive to DCMU" EXACT [CHEBI:116509] synonym: "sensitive to diuron during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to diuron during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T12:53:25Z" xsd:dateTime [Term] id: FYPO:0007617 name: sensitive to sodium azide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium azide (NaN3). Cells stop growing (and may die) at a concentration of sodium azide that allows wild type cells to grow." [PomBase:mah] synonym: "sensitive to NaN3" EXACT [PomBase:mah] synonym: "sensitive to sodium azide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to sodium azide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T12:54:42Z" xsd:dateTime [Term] id: FYPO:0007618 name: delayed onset of protein export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus begins later than normal. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein export from nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein export from nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein export from nucleus" EXACT [PomBase:mah] is_a: FYPO:0000345 ! abnormal protein export from nucleus during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T13:09:11Z" xsd:dateTime [Term] id: FYPO:0007619 name: normal protein localization to chromatin during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) when the cell is subject to oxidative stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during oxidative stress response" EXACT [PomBase:mah] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T13:40:59Z" xsd:dateTime [Term] id: FYPO:0007620 name: decreased protein phosphorylation during cellular response to oxidative stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal when the cell is subject to oxidative stress." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein phosphorylation during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during oxidative stress response" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T13:43:28Z" xsd:dateTime [Term] id: FYPO:0007621 name: increased protein-protein interaction during cellular response to oxidative stress def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal when the cell is subject to oxidative stress. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein binding during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "increased protein-protein interaction during oxidative stress response" EXACT [PomBase:mah] is_a: FYPO:0001571 ! increased protein-protein interaction property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T13:51:59Z" xsd:dateTime [Term] id: FYPO:0007622 name: increased cellular reactive oxygen species level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the cell is subject to oxidative stress." [PomBase:mah] synonym: "increased cellular reactive oxygen species accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular reactive oxygen species level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular reactive oxygen species level during oxidative stress response" EXACT [PomBase:mah] synonym: "increased cellular ROS accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "increased cellular ROS level during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "increased ROS accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] is_a: FYPO:0002142 ! altered cellular reactive oxygen species level property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T13:53:52Z" xsd:dateTime [Term] id: FYPO:0007623 name: decreased mitochondrial respiratory chain complex III assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial respiratory chain complex III assembly is decreased." [GO:0034551, PomBase:mah] synonym: "decreased mitochondrial respiratory chain complex III assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial respiratory chain complex III assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased respiratory chain complex III assembly" EXACT [PomBase:vw] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T15:06:32Z" xsd:dateTime [Term] id: FYPO:0007624 name: decreased mitochondrial respiratory chain complex IV assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial cytochrome c oxidase (respiratory chain complex IV) assembly is decreased." [GO:0033617, PomBase:mah] synonym: "decreased mitochondrial cytochrome c oxidase assembly" EXACT [GO:0033617] synonym: "decreased mitochondrial respiratory chain complex IV assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial respiratory chain complex IV assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased respiratory chain complex IV assembly" EXACT [PomBase:vw] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T15:24:01Z" xsd:dateTime [Term] id: FYPO:0007625 name: mitochondrial respiratory chain complex III absent from cell def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which does not contain a detectable mitochondrial respiratory chain complex III." [PomBase:mah] synonym: "absent respiratory complex III" EXACT [PomBase:vw] synonym: "mitochondrial respiratory chain complex III absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondrial respiratory chain complex III absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-01-27T15:33:01Z" xsd:dateTime [Term] id: FYPO:0007626 name: normal protein oxidation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oxidation is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein oxidation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "normal protein oxidation during cellular response to hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein oxidation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein/peptide oxidation during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0002013 ! normal protein oxidation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-01T13:37:14Z" xsd:dateTime [Term] id: FYPO:0007627 name: decreased RNA catabolic process during glucose starvation def: "A cellular process phenotype which the occurrence of an RNA catabolic process is decreased when the cell is subject to glucose starvation." [PomBase:mah] synonym: "decreased RNA breakdown process during glucose starvation" EXACT [GO:0006401] synonym: "decreased RNA catabolic process during glucose depletion" EXACT [PomBase:mah] synonym: "decreased RNA catabolic process during glucose deprivation" EXACT [PomBase:mah] synonym: "decreased RNA catabolic process during glucose limitation" EXACT [PomBase:mah] synonym: "decreased RNA catabolism during glucose starvation" EXACT [GO:0006401] synonym: "decreased RNA degradation during glucose starvation" EXACT [GO:0006401] synonym: "reduced RNA catabolic process during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0003552 ! decreased RNA catabolic process property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-01T14:03:24Z" xsd:dateTime [Term] id: FYPO:0007628 name: abnormal chromatin organization during mitotic G2 phase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal during G2 phase of the mitotic cell cycle." [PomBase:mah] synonym: "abnormal chromatin organisation during mitotic G2 phase" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during G2 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal chromatin organization during mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-01T15:33:39Z" xsd:dateTime [Term] id: FYPO:0007629 name: normal viability during G0 def: "A cell population phenotype in which a normal proportion of cells in the population remains viable during G0 phase." [PomBase:mah] synonym: "maintains viability in G0" EXACT [PomBase:mah] synonym: "normal cell population viability during G0" EXACT [PomBase:mah] synonym: "normal G0 maintenance" EXACT [PomBase:mah] synonym: "normal viability during cell quiescence" EXACT [PomBase:mah] synonym: "normal viability during quiescence" EXACT [PomBase:mah] synonym: "normal viability in G0" EXACT [PomBase:mah] is_a: FYPO:0002057 ! cell population viability property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-01T15:43:23Z" xsd:dateTime [Term] id: FYPO:0007630 name: increased histone H3-K9 acetylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 9 of histone H3 at ribosomal DNA occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K9 acetylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 acetylation at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 acetylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:55Z" xsd:dateTime [Term] id: FYPO:0007631 name: increased histone H4-K12 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 12 of histone H4 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K12 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K12 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:55Z" xsd:dateTime [Term] id: FYPO:0007632 name: increased histone H4-K16 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 16 of histone H4 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K16 acetylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K16 acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:56Z" xsd:dateTime [Term] id: FYPO:0007633 name: increased histone H3-K14 acetylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 14 of histone H3 at the silent mating-type cassettes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation at silent mating-type cassette during mitotic cell cycle" RELATED [PomBase:mahle] synonym: "increased histone H3K14 acetylation at mating-type region heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K14 acetylation at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:56Z" xsd:dateTime [Term] id: FYPO:0007634 name: increased histone H3-K14 acetylation at rDNA during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 14 of histone H3 at ribosomal DNA occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation at rDNA during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K14 acetylation at rDNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K14 acetylation at ribosomal DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0005310 ! increased histone H3-K14 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:56Z" xsd:dateTime [Term] id: FYPO:0007635 name: increased histone H4-K16 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 16 of histone H4 in regions containing protein coding genes occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H4-K16 acetylation at protein coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H4K16 acetylation at protein coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H4K16 acetylation at protein-coding gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007632 ! increased histone H4-K16 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:56Z" xsd:dateTime [Term] id: FYPO:0007636 name: increased histone H3-K9 acetylation at promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 9 of histone H3 in one or more promoter regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K9 acetylation at promoter during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 acetylation at promoter during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-03T11:24:56Z" xsd:dateTime [Term] id: FYPO:0007637 name: decreased chromatin mobility def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromatin moves within the nucleus to a lower extent than normal." [PMID:33434270, PomBase:mah] synonym: "decreased chromatin mobility during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased chromatin mobility during vegetative growth" EXACT [PomBase:mah] synonym: "decreased chromatin motility" EXACT [PomBase:mah] synonym: "decreased chromatin movement" EXACT [PomBase:mah] synonym: "reduced chromatin mobility" EXACT [PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T14:12:00Z" xsd:dateTime [Term] id: FYPO:0007638 name: decreased anisotropic motion of mitotic chromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the anisotropic movement of chromatin occurs to a lower extent than normal during mitosis. Normally, chromatin moves to a lesser extent, and with less freedom of movement direction (i.e. more anisotropically), during mitosis than during interphase." [PMID:33434270, PomBase:mah] synonym: "decreased anisotropic chromatin motion during mitosis" EXACT [PomBase:mah] synonym: "decreased anisotropic chromatin motion during mitotic M phase" RELATED [PomBase:mah] synonym: "decreased anisotropic chromatin movement during mitosis" EXACT [PomBase:mah] synonym: "decreased anisotropic mitotic chromatin mobility" EXACT [PomBase:mah] synonym: "decreased anisotropic mitotic chromatin motion" EXACT [PomBase:mah] synonym: "decreased anisotropic motion of mitotic chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "decreased anisotropic movement of mitotic chromatin" EXACT [PomBase:mah] synonym: "reduced anisotropic motion of mitotic chromatin" EXACT [PMID:33434270] is_a: FYPO:0007637 ! decreased chromatin mobility property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T14:13:13Z" xsd:dateTime [Term] id: FYPO:0007639 name: increased DNA damage at rDNA during G0 def: "A cell phenotype in which the amount of DNA damage measured at ribosomal DNA in a cell is greater than normal during G0 phase. The number, extent, or both of damage sites may be increased." [PMID:27738016, PomBase:mah] synonym: "increased DNA damage at rDNA during cell quiescence" EXACT [PomBase:mah] synonym: "increased DNA damage at rDNA during quiescence" EXACT [PomBase:mah] synonym: "increased DNA damage at ribosomal DNA" EXACT [PomBase:mah] is_a: FYPO:0003546 ! increased DNA damage property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T14:51:15Z" xsd:dateTime [Term] id: FYPO:0007640 name: increased histone H3-K9 dimethylation at rDNA during G0 def: "A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at ribosomal DNA during G0 phase." [PMID:27738016, PomBase:mah] synonym: "increased histone H3 K9 dimethylation at rDNA during G0" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at rDNA during cell quiescence" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at rDNA during quiescence" EXACT [PomBase:mah] synonym: "increased histone H3-K9 dimethylation at ribosomal DNA during G0" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation at rDNA during G0" EXACT [PomBase:mah] synonym: "increased histone H3K9me2 dimethylation at rDNA during G0" EXACT [PomBase:mah] is_a: FYPO:0007470 ! abnormal histone modification during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T14:56:34Z" xsd:dateTime [Term] id: FYPO:0007641 name: decreased histone H3-K9 methylation during G0 def: "A cellular process phenotype in which the methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal during G0 phase." [PMID:27738016, PomBase:mah] synonym: "decreased histone H3 K9 methylation during G0" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 methylation during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 methylation during quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3K9 methylation during G0" EXACT [PomBase:mah] synonym: "decreased histone H3K9me2 methylation during G0" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 methylation during G0" EXACT [PomBase:mah] is_a: FYPO:0007470 ! abnormal histone modification during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T14:59:32Z" xsd:dateTime [Term] id: FYPO:0007642 name: decreased histone H3-K9 dimethylation at rDNA during G0 def: "A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal at ribosomal DNA during G0 phase." [PMID:27738016, PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at rDNA during G0" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at rDNA during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at rDNA during quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at ribosomal DNA during G0" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at rDNA during G0" EXACT [PomBase:mah] synonym: "decreased histone H3K9me2 dimethylation at rDNA during G0" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at rDNA during G0" EXACT [PomBase:mah] is_a: FYPO:0007641 ! decreased histone H3-K9 methylation during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T15:00:35Z" xsd:dateTime [Term] id: FYPO:0007643 name: decreased histone H3-K9 dimethylation at centromere outer repeat during G0 def: "A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal in centromere outer repeat regions during G0 phase." [PMID:27738016, PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere outer repeat during G0" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere otr during G0" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere outer repeat during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere outer repeat during quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at pericentric region during G0" RELATED [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at pericentromeric region during G0" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere outer repeat during G0" EXACT [PomBase:mah] synonym: "decreased histone H3K9me2 dimethylation at centromere outer repeat during G0" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at centromere outer repeat during G0" EXACT [PomBase:mah] is_a: FYPO:0007641 ! decreased histone H3-K9 methylation during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T15:09:37Z" xsd:dateTime [Term] id: FYPO:0007644 name: decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during G0 def: "A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal in subtelomeric regions occurs during G0 phase." [PMID:27738016, PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at subtelomeric heterochromatin during G0" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at subtelomere during G0" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during cell quiescence" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during quiescence" RELATED [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at subtelomeric heterochromatin during G0" EXACT [PomBase:mah] synonym: "decreased histone H3K9me2 dimethylation at subtelomeric heterochromatin during G0" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at subtelomeric heterochromatin during G0" EXACT [PomBase:mah] is_a: FYPO:0007641 ! decreased histone H3-K9 methylation during G0 property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T15:10:43Z" xsd:dateTime [Term] id: FYPO:0007645 name: abnormal chromosome segregation during G1 to G0 transition def: "A cellular process phenotype in which chromosome segregation is abnormal during one or both of the cell divisions that a cell undergoes prior to entering quiescence (G0)." [PMID:27738016, PomBase:mah] synonym: "abnormal chromosome segregation during establishment of cell quiescence" EXACT [PomBase:mah] synonym: "abnormal chromosome segregation during G1/G0 transition" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-10T15:23:23Z" xsd:dateTime [Term] id: FYPO:0007646 name: septated mononucleate vegetative cell with mislocalized nucleus and anucleate compartment def: "A cell phenotype in which a vegetatively growing cell has one or more septa, and one nucleus that is not in the normal location. The cell also has one or more compartments with no nucleus." [PomBase:mah] synonym: "cytokinesis in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "cytokinesis without nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "mononucleate septated vegetative cell with mislocalized nucleus" EXACT [PomBase:mah] synonym: "septated mononucleate cell" EXACT [PomBase:vw] synonym: "septated mononucleate cell with abnormal nucleus location" EXACT [PomBase:mah] synonym: "septated mononucleate cell with abnormal nucleus position" EXACT [PomBase:mah] synonym: "septated mononucleate cell with asymmetrically localized nucleus" EXACT [PomBase:vw] synonym: "septated mononucleate cell with displaced nucleus" EXACT [PomBase:mah] synonym: "septated mononucleate cell with mislocalised nucleus" EXACT [PomBase:mah] synonym: "septated mononucleate cell with mislocalized nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "septated mononucleate cell with misplaced nucleus" EXACT [PomBase:mah] synonym: "septated mononucleate vegetative cell with mislocalized nucleus" EXACT [PomBase:mah] synonym: "septated mononucleate vegetative cell with mislocalized nucleus during mitotic cell cycle" RELATED [PomBase:mah] synonym: "septated vegetative cell with mislocalized mononucleus" EXACT [PomBase:vw] synonym: "septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "septation without nuclear division" RELATED [PomBase:al, PomBase:vw] is_a: FYPO:0002342 ! septated vegetative cell is_a: FYPO:0006339 ! mononucleate vegetative cell with mislocalized nucleus property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-17T15:13:55Z" xsd:dateTime [Term] id: FYPO:0007647 name: inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase and normal nucleus localization def: "A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus in the normal location, has no septum, and progression through the mitotic cell cycle is arrested in M phase." [PMID:33506191, PomBase:mah] synonym: "elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest in M phase and normal nucleus localization during vegetative growth" EXACT [PomBase:mah] synonym: "elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase and normal nucleus localization" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell arrested in M with normal nucleus localization" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in M phase and normal nucleus localization during mitotic cell cycle" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitosis and normal nucleus localization" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase and normal nuclear localization" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase and normal nuclear position" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase and normal nucleus localisation" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase and normal nucleus localization" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest in M phase and normal nucleus localization" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic M phase arrest and normal nucleus localization" EXACT [PomBase:vw] synonym: "inviable elongated mononucleate aseptate vegetative cell with mitotic nuclear division arrest and normal nucleus localization" EXACT [PomBase:vw] synonym: "inviable mononucleate aseptate cell arrested in mitotic M phase without nuclear displacement" EXACT [PomBase:vw] synonym: "lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase and normal nucleus localization" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in M-phase with elongated inviable mononucleate aseptate cell and normal nucleus localization" EXACT [PomBase:vw] synonym: "mitotic M-phase arrested elongated inviable mononucleate aseptate vegetative cell with normal nucleus localization" EXACT [PomBase:mah] synonym: "nuclear division arrest without septation (elongated cell) with normal nucleus localization" EXACT [PomBase:vw] is_a: FYPO:0000608 ! abnormal cell cycle arrest in mitotic M phase is_a: FYPO:0002070 ! normal nucleus location is_a: FYPO:0003763 ! inviable aseptate mononucleate vegetative cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-17T16:19:36Z" xsd:dateTime [Term] id: FYPO:0007648 name: abnormal protein localization to pericentric heterochromatin def: "A cell phenotype in which the localization of a protein to pericentric heterochromatin is abnormal." [GO:1902682, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localization to centromeric heterochromatin" EXACT [GO:0005721] synonym: "abnormal protein localization to nuclear centromeric heterochromatin" EXACT [PomBase:mah] is_a: FYPO:0001679 ! abnormal protein localization to chromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T12:14:14Z" xsd:dateTime [Term] id: FYPO:0007649 name: abolished protein localization to pericentric heterochromatin during meiosis II def: "A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during the second meiotic nuclear division." [PMID:14730319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to centromeric heterochromatin during meiosis II" EXACT [GO:0005721] synonym: "abolished protein localization to nuclear centromeric heterochromatin during meiosis II" EXACT [PomBase:mah] synonym: "abolished protein localization to pericentric heterochromatin during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007648 ! abnormal protein localization to pericentric heterochromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T13:54:57Z" xsd:dateTime [Term] id: FYPO:0007650 name: abolished protein localization to pericentric heterochromatin during meiotic prophase I def: "A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during prophase of the first meiotic nuclear division." [PMID:14730319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to centromeric heterochromatin during meiotic prophase I" EXACT [GO:0005721] synonym: "abolished protein localization to nuclear centromeric heterochromatin during meiotic prophase I" EXACT [PomBase:mah] synonym: "abolished protein localization to pericentric heterochromatin during prophase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0007648 ! abnormal protein localization to pericentric heterochromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T14:01:31Z" xsd:dateTime [Term] id: FYPO:0007651 name: abolished protein localization to pericentric heterochromatin during mitosis def: "A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during mitosis." [PMID:14730319, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to centromeric heterochromatin during mitosis" EXACT [GO:0005721] synonym: "abolished protein localization to nuclear centromeric heterochromatin during mitosis" EXACT [PomBase:mah] synonym: "abolished protein localization to pericentric heterochromatin during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to pericentric heterochromatin during mitotic M phase" RELATED [PomBase:mah] synonym: "abolished protein localization to pericentric heterochromatin during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0007648 ! abnormal protein localization to pericentric heterochromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T14:06:20Z" xsd:dateTime [Term] id: FYPO:0007652 name: mononucleate vegetative cell with mislocalized septum and anucleate compartment def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single nucleus and an asymmetrically located septum. The septum divides the cell into two compartments, one of which contains the nucleus." [PomBase:mah] synonym: "mononucleate cell with mislocalized septum and anucleate compartment during vegetative growth" EXACT [PomBase:mah] synonym: "mononucleate monoseptate vegetative cell with mislocalized septum and anucleate compartment" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with abnormal septum location and anucleate compartment" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with abnormal septum position and anucleate compartment" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with asymmetric septum and anucleate compartment" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with asymmetrically located septum and anucleate compartment" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with mislocalised septum and anucleate compartment" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with mislocalized septum" EXACT [PomBase:mah] synonym: "mononucleate vegetative cell with mislocalized septum and anucleate compartment during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mononucleate vegetative cell with misplaced septum and anucleate compartment" EXACT [PomBase:vw] synonym: "mononucleate vegetative cell with single mislocalized septum and anucleate compartment" EXACT [PomBase:mah] is_a: FYPO:0000339 ! mislocalized septum during vegetative growth is_a: FYPO:0007664 ! mononucleate monoseptate vegetative cell with anucleate compartment property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T15:15:58Z" xsd:dateTime [Term] id: FYPO:0007653 name: decreased histone H3-K9 trimethylation at heterochromatin island at meiotic gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 is decreased at heterochromatin islands near genes that are normally expressed during the meiotic cell cycle." [PMID:32269268, PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at heterochromatin island at meiosis gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at heterochromatin island at meiotic gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9me3 at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000882 ! decreased histone H3-K9 trimethylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T15:33:44Z" xsd:dateTime [Term] id: FYPO:0007654 name: decreased protein localization to heterochromatin island at meiotic gene during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of localization of a protein at a location in heterochromatin at heterochromatin islands occurs to a lower extent than normal." [PMID:32269268, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to chromatin at heterochromatin island at meiotic gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at heterochromatin island at meiosis gene during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromatin at heterochromatin island at meiotic gene during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0002385 ! decreased protein localization to heterochromatin during vegetative growth is_a: FYPO:0008418 ! abnormal protein localization to heterochromatin island property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T15:39:49Z" xsd:dateTime [Term] id: FYPO:0007655 name: increased nucleosome occupancy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at one or more specific sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:33511417, PomBase:mah] synonym: "increased nucleosome occupancy during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000853 ! abnormal nucleosome positioning property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T16:00:13Z" xsd:dateTime [Term] id: FYPO:0007656 name: increased nucleosome occupancy at transcription start site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at transcription start sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:33511417, PomBase:mah] synonym: "increased nucleosome occupancy at transcription start site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy at transcription start site during vegetative growth" EXACT [PomBase:mah] synonym: "increased nucleosome occupancy at TSS" EXACT [PomBase:mah] is_a: FYPO:0007655 ! increased nucleosome occupancy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T16:01:13Z" xsd:dateTime [Term] id: FYPO:0007657 name: decreased protein localization to linear element at meiotic recombination hotspot def: "A cell phenotype in which the localization of a protein to linear elements is decreased at one or more meiotic recombination hotspots." [PMID:23395004, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased linear element chromatin binding at meiotic DNA double-strand break hotspots" EXACT [PMID:23395004] synonym: "decreased protein localisation to linear element at meiotic recombination hotspot" EXACT [PomBase:mah] synonym: "reduced protein localization to linear element at meiotic recombination hotspot" EXACT [PomBase:mah] is_a: FYPO:0006164 ! decreased protein localization to linear element property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-02-23T16:02:57Z" xsd:dateTime [Term] id: FYPO:0007658 name: shmoo with flat tip def: "A cell morphology phenotype in which a cell forms a mating projection with a flatter (less rounded) tip than normal." [PMID:9606213, PomBase:mah] synonym: "conjugation tube with flat tip" EXACT [PomBase:mah] synonym: "mating projection with flat tip" EXACT [PomBase:mah] synonym: "shmoo with flattened tip" EXACT [PATO:0002254] is_a: FYPO:0000357 ! abnormal shmoo morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T11:36:15Z" xsd:dateTime [Term] id: FYPO:0007659 name: variable cell size at division with subsequent division at normal size def: "A cell population phenotype in which cells in a population do not divide at a uniform size, although each cell divides to form equal-size daughter cells, which then subsequently divide at a normal size. Within one population, some cells may be larger and others smaller than normal (i.e. compared to wild-type cells under the same conditions) upon the first division. Daughter cells that are larger than normal upon formation divide earlier, and smaller-formed daughter cells divide later, than cells formed at a normal size." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "increased variability of cell size in a vegetative population, with subsequent division at normal size" EXACT [PomBase:vw] synonym: "variable cell length at entry into mitosis followed by equal cell division" EXACT [PomBase:jh] synonym: "variable cell size at division with normal cell size homeostasis" EXACT [PomBase:jh] synonym: "variable cell size at division with subsequent division at normal size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "variable cell size at division with subsequent division at normal size during vegetative growth" EXACT [PomBase:mah] synonym: "variable vegetative cell size at division with subsequent division at normal size" EXACT [PomBase:mah] is_a: FYPO:0007474 ! variable cell size at division property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T13:48:07Z" xsd:dateTime [Term] id: FYPO:0007660 name: variable cell size at division with subsequent division at abnormal size def: "A cell population phenotype in which cells in a population do not divide at a uniform size, although each cell divides to form equal-size daughter cells, which then subsequently divide at an abnormal size. Within one population, some cells may be larger and others smaller than normal (i.e. compared to wild-type cells under the same conditions) upon each division." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "increased variability of cell size in a vegetative population, with subsequent division at abnormal size" EXACT [PomBase:vw] synonym: "variable cell length at entry into mitosis followed by unequal cell division" EXACT [PomBase:jh] synonym: "variable cell size at division with abnormal cell size homeostasis" EXACT [PomBase:jh] synonym: "variable cell size at division with loss of cell size homeostasis" EXACT [PomBase:jh] synonym: "variable cell size at division with subsequent division at abnormal size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "variable cell size at division with subsequent division at abnormal size during vegetative growth" EXACT [PomBase:mah] synonym: "variable vegetative cell size at division with subsequent division at abnormal size" EXACT [PomBase:mah] is_a: FYPO:0007474 ! variable cell size at division property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T13:49:49Z" xsd:dateTime [Term] id: FYPO:0007661 name: normal protein localization to kinetochore during meiotic metaphase I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during metaphase of meiosis I." [PMID:11331883, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during meiotic metaphase I" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during meiosis I metaphase" EXACT [PomBase:vw] is_a: FYPO:0004214 ! normal protein localization to kinetochore during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T14:15:54Z" xsd:dateTime [Term] id: FYPO:0007662 name: abolished protein localization to kinetochore during meiotic anaphase I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during anaphase of the first meiotic nuclear division." [PMID:11331883, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during meiotic anaphase I" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during meiosis I anaphase" EXACT [PomBase:vw] is_a: FYPO:0004763 ! abolished protein localization to kinetochore during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T14:26:24Z" xsd:dateTime [Term] id: FYPO:0007663 name: abolished protein localization to kinetochore during meiosis II def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during the second meiotic nuclear division." [PMID:11331883, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during meiosis II" EXACT [PomBase:mah] synonym: "abolished protein localisation to kinetochore during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004762 ! abnormal protein localization to kinetochore during meiosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T14:29:40Z" xsd:dateTime [Term] id: FYPO:0007664 name: mononucleate monoseptate vegetative cell with anucleate compartment def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus." [PomBase:mah] comment: Most mononucleate monoseptate cells are inviable (cf. FYPO:0002303), and the viable cells (FYPO:0007665) are diploid. synonym: "displaced nucleus with septum" RELATED [PMID:7798319] synonym: "mononucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] synonym: "mononucleate monoseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "monoseptate vegetative cell with mononucleate and anucleate compartments" EXACT [PomBase:mah] synonym: "septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "septation without nuclear division" RELATED [PomBase:al, PomBase:vw] is_a: FYPO:0000060 ! mononucleate vegetative cell is_a: FYPO:0002342 ! septated vegetative cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T14:53:03Z" xsd:dateTime [Term] id: FYPO:0007665 name: viable mononucleate monoseptate vegetative cell with anucleate compartment def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, and contains one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus." [PomBase:mah] synonym: "displaced nucleus with septum" RELATED [PMID:7798319] synonym: "viable mononucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "viable mononucleate monoseptate vegetative cell" EXACT [PomBase:mah] synonym: "viable mononucleate monoseptate vegetative cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable with septation in the absence of nuclear division" RELATED [PomBase:al, PomBase:vw] synonym: "viable with septation independent of mitosis" RELATED [PomBase:al, PomBase:vw] synonym: "viable with septation without nuclear division" RELATED [PomBase:al, PomBase:vw] is_a: FYPO:0001491 ! viable vegetative cell is_a: FYPO:0007664 ! mononucleate monoseptate vegetative cell with anucleate compartment property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-02T14:54:38Z" xsd:dateTime [Term] id: FYPO:0007666 name: normal establishment or maintenance of actin cytoskeleton polarity during mating def: "A cellular process phenotype in which the establishment or maintenance of actin cytoskeleton polarity is normal (i.e. indistinguishable from wild type) during conjugation with cellular fusion." [PMID:9606213, PomBase:mah] synonym: "normal actin cytoskeleton polarisation during conjugation" RELATED [PomBase:mah] synonym: "normal actin cytoskeleton polarisation during mating" RELATED [PomBase:mah] synonym: "normal actin cytoskeleton polarization during conjugation" RELATED [PomBase:mah] synonym: "normal actin cytoskeleton polarization during mating" RELATED [PomBase:mah] synonym: "normal actin polarisation during mating" RELATED [PomBase:vw] synonym: "normal actin polarisation in shmoo during mating" NARROW [PomBase:vw] synonym: "normal actin polarization during mating" RELATED [PomBase:vw] synonym: "normal actin polarization in shmoo during mating" NARROW [PomBase:vw] synonym: "normal establishment or maintenance of actin cytoskeleton polarity during conjugation" EXACT [PomBase:mah] is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T12:03:29Z" xsd:dateTime [Term] id: FYPO:0007667 name: increased protein localization to shmoo tip def: "A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, is decreased." [PMID:9606213, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to shmoo tip" EXACT [PomBase:mah] synonym: "increased protein localization to mating projection tip" EXACT [PomBase:mah] is_a: FYPO:0004802 ! abnormal protein localization to shmoo tip property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T12:09:51Z" xsd:dateTime [Term] id: FYPO:0007668 name: elongated vegetative cell with cell cycle arrest in mitotic G1 phase def: "A cell phenotype in which a vegetative cell is elongated and progression through the mitotic cell cycle is arrested in G1 phase." [PMID:8121488, PomBase:mah] synonym: "abnormal cell cycle arrest in mitotic G1 phase with elongated cell" EXACT [PomBase:vw] synonym: "elongated cell with cell cycle arrest in mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "elongated vegetative cell with cell cycle arrest in G1 phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "elongated vegetative cell with mitotic G1 phase cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0000445 ! cell cycle arrest in mitotic G1 phase is_a: FYPO:0001122 ! elongated vegetative cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T13:12:49Z" xsd:dateTime [Term] id: FYPO:0007669 name: viable swollen vegetative cell with complete DNA rereplication def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, has a larger volume than normal, and undergoes one or more rounds of rereplication of the entire genome. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PMID:8121488, PomBase:mah] synonym: "viable enlarged vegetative cell with complete DNA rereplication" RELATED [PomBase:mah] synonym: "viable large vegetative cell with complete DNA rereplication" RELATED [PomBase:vw] synonym: "viable swollen cell with complete DNA rereplication during vegetative growth" EXACT [PomBase:mah] synonym: "viable swollen vegetative cell with abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication" EXACT [PomBase:mah] synonym: "viable swollen vegetative cell with complete DNA rereplication during mitotic cell cycle" RELATED [PomBase:mah] synonym: "viable swollen vegetative cell with increased ploidy" EXACT [PomBase:vw] synonym: "viable vegetative cell with increased cell size and complete DNA rereplication" RELATED [PomBase:vw] synonym: "viable vegetative cell with increased cell volume and complete DNA rereplication" EXACT [PomBase:mah] is_a: FYPO:0000216 ! abnormal negative regulation of mitotic DNA replication initiation is_a: FYPO:0002377 ! viable swollen vegetative cell property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T13:27:55Z" xsd:dateTime [Term] id: FYPO:0007670 name: inviable mononucleate monoseptate vegetative cell with anucleate compartment and normal cell length def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is normal length, and has one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus." [PMID:9862966, PomBase:mah] synonym: "inviable mononucleate monoseptate cell with anucleate compartment and normal cell length during vegetative growth" EXACT [PomBase:mah] synonym: "inviable mononucleate monoseptate vegetative cell with normal cell length" EXACT [PomBase:mah] synonym: "inviable mononucleate monoseptate vegetative cell with normal cell length during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable with septation in the absence of nuclear division; normal cell length" RELATED [PomBase:al, PomBase:vw] synonym: "inviable with septation independent of mitosis, normal cell length" RELATED [PomBase:al, PomBase:vw] synonym: "inviable with septation without nuclear division; normal cell length" RELATED [PomBase:al, PomBase:vw] synonym: "lethal; mononucleate monoseptate vegetative cell with normal cell length" EXACT [PomBase:mah] is_a: FYPO:0002303 ! inviable mononucleate monoseptate vegetative cell with anucleate compartment is_a: FYPO:0003503 ! normal vegetative cell length property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T14:07:35Z" xsd:dateTime [Term] id: FYPO:0007671 name: normal transcription scaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the coordination of transcription rates to scale linearly with cell size is normal (i.e. indistinguishable from wild type). Transcriptional scaling maintains biomolecule concentrations as cells grow and divide. Total RNA or a specific RNA may be measured." [PMID:32059768, PomBase:mah] synonym: "normal linear transcription scaling with cell size" EXACT [PomBase:mah] synonym: "normal transcription scaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal transcription scaling during vegetative growth" EXACT [PomBase:mah] synonym: "normal transcription scaling with cell size" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T15:14:04Z" xsd:dateTime [Term] id: FYPO:0007672 name: transcription scaling with nuclear size decoupled from cell size def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of transcription scales linearly with nuclear size instead of total cell size. Total RNA or a specific RNA may be affected." [PMID:32059768, PomBase:mah] synonym: "abnormal transcription scaling with nuclear size" EXACT [PomBase:mah] synonym: "linear transcription scaling with nuclear size decoupled from cell size" EXACT [PomBase:mah] synonym: "transcription scaling with nuclear size decoupled from cell size during mitotic cell cycle" RELATED [PomBase:mah] synonym: "transcription scaling with nuclear size decoupled from cell size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T15:15:05Z" xsd:dateTime [Term] id: FYPO:0007673 name: abolished invertase activity def: "A molecular function phenotype in which invertase activity (beta-fructofuranosidase activity) is absent." [PomBase:mah] synonym: "abolished beta-fructofuranosidase activity" EXACT [GO:0004564] synonym: "invertase activity abolished" EXACT [GO:0004564] is_a: FYPO:0005741 ! abnormal invertase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T15:17:09Z" xsd:dateTime [Term] id: FYPO:0007674 name: increased invertase activity def: "A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is increased." [PomBase:mah] synonym: "increased beta-fructofuranosidase activity" EXACT [GO:0004564] is_a: FYPO:0005741 ! abnormal invertase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T15:19:01Z" xsd:dateTime [Term] id: FYPO:0007675 name: abolished cell population growth on sucrose carbon source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing sucrose as the carbon source." [PomBase:mah] comment: Use this term for a population of cells that does not grow with sucrose as the carbon source, but does grow using a different carbon source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on sucrose carbon source" BROAD [PomBase:mah] synonym: "abolished sucrose utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on sucrose carbon source" EXACT [PomBase:mah] synonym: "cell population growth on sucrose carbon source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-09T15:57:15Z" xsd:dateTime [Term] id: FYPO:0007676 name: normal intracellular sterol transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the directed movement of sterols within cells is normal (i.e. indistinguishable from wild type)." [PMID:32320462, PomBase:mah] is_a: FYPO:0001071 ! normal transport property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-10T15:49:06Z" xsd:dateTime [Term] id: FYPO:0007677 name: abnormal sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in cellular membranes is abnormal." [PMID:32320462, PomBase:mah] is_a: FYPO:0006545 ! abnormal membrane lipid distribution property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-10T15:57:48Z" xsd:dateTime [Term] id: FYPO:0007678 name: normal sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in cellular membranes is normal (i.e. indistinguishable from wild type)." [PMID:32320462, PomBase:mah] is_a: FYPO:0006546 ! normal membrane lipid distribution property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-10T16:00:17Z" xsd:dateTime [Term] id: FYPO:0007679 name: increased replication fork arrest at RTS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the RTS1 barrier (normally located in the mating-type region) occurs to a greater extent than normal." [PMID:33568651, PomBase:mah] is_a: FYPO:0003088 ! abnormal replication fork arrest property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-10T16:21:55Z" xsd:dateTime [Term] id: FYPO:0007680 name: increased ribonucleotide incorporation into DNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which more ribonucleotides than normal are incorporated into one or both strands during mitotic DNA replication." [PMID:33568651, PomBase:mah] is_a: FYPO:0001343 ! abnormal mitotic DNA replication property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-10T16:35:30Z" xsd:dateTime [Term] id: FYPO:0007681 name: abnormal RNA-DNA hybrid ribonuclease activity def: "A molecular function phenotype in which the observed rate or other catalytic property of a RNA-DNA hybrid ribonuclease activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-10T16:39:30Z" xsd:dateTime [Term] id: FYPO:0007682 name: abnormal cortical polarity patch dynamics during mating def: "A cellular process phenotype in which assembly, exploratory movement, or disassembly of the Cdc42-containing cortical polarity patch is abnormal during mating." [PMID:30279276, PomBase:mah] synonym: "abnormal cortical polarity patch dynamics during conjugation with cellular fusion" EXACT [GO:0000747, PomBase:mah] synonym: "altered cortical polarity patch dynamics during mating" EXACT [PMID:30279276] is_a: FYPO:0000031 ! abnormal mating property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T14:02:06Z" xsd:dateTime [Term] id: FYPO:0007683 name: wide actin fusion focus def: "A physical cellular phenotype in which components of the actin fusion focus are more widely distributed along the shmoo tip than normal." [PMID:28410370, PomBase:mah] synonym: "increased actin fusion focus diameter" EXACT [PomBase:mah] synonym: "increased actin fusion focus width" EXACT [PomBase:mah] synonym: "wider actin fusion focus" EXACT [PMID:28410370, PomBase:sm] is_a: FYPO:0005665 ! abnormal actin cytoskeleton property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T14:17:17Z" xsd:dateTime [Term] id: FYPO:0007684 name: increased level of early meiotic gene mRNA during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from early meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination." [PMID:33574613, PomBase:mah] synonym: "increased level of early meiosis gene mRNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of early meiotic gene mRNA during vegetative growth during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased level of early meiotic gene RNA during vegetative growth" EXACT [PomBase:mah] synonym: "increased level of early meiotic gene transcripts during vegetative growth" EXACT [PomBase:vw] is_a: FYPO:0002173 ! increased level of meiotic gene mRNA during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T14:27:41Z" xsd:dateTime [Term] id: FYPO:0007685 name: increased vegetative cell population growth during nutrient starvation def: "A cell growth phenotype in which vegetative cell population growth is increased relative to normal under conditions of starvation for one or more nutrients." [PMID:33574613, PomBase:mah] synonym: "fast vegetative cell population growth during nutrient starvation" NARROW [PomBase:mah] synonym: "increased vegetative cell population growth during nutrient depletion" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during nutrient deprivation" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth during nutrient limitation" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth in response to nutrient starvation" EXACT [PomBase:mah] synonym: "resistant to nutrient starvation" RELATED [PomBase:mah] is_a: FYPO:0004557 ! increased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T14:35:26Z" xsd:dateTime [Term] id: FYPO:0007686 name: increased number of nuclear exosome foci def: "A cell phenotype in which the cell contains more nuclear exosome foci than normal." [PMID:33574613, PomBase:mah] synonym: "increased number of Mmi1 foci" EXACT [PomBase:mah] synonym: "increased number of Mmi1 nuclear foci" EXACT [GO:1990251] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T14:40:59Z" xsd:dateTime [Term] id: FYPO:0007687 name: normal protein localization to nuclear exosome focus during meiosis def: "A cell phenotype in which the localization of a protein to nuclear exosome foci is normal (i.e. indistinguishable from wild type) during meiosis. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle." [PMID:33574613, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nuclear exosome focus during meiosis" EXACT [PomBase:mah] synonym: "normal protein localization to Mmi1 focus during meiosis" EXACT [PomBase:mah] synonym: "normal protein localization to Mmi1 nuclear focus during meiosis" EXACT [GO:1990251] synonym: "normal protein localization to nuclear exosome foci during meiosis" EXACT [PomBase:mah] synonym: "normal protein localization to nuclear exosome focus during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T14:54:26Z" xsd:dateTime [Term] id: FYPO:0007688 name: abolished protein localization to kinetochore during meiotic metaphase I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during metaphase of the first meiotic nuclear division." [PMID:16541024, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore during meiotic metaphase I" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during meiosis I metaphase" EXACT [PomBase:vw] synonym: "protein localization to kinetochore abolished during meiotic metaphase I" EXACT [PomBase:mah] is_a: FYPO:0004763 ! abolished protein localization to kinetochore during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-16T16:17:57Z" xsd:dateTime [Term] id: FYPO:0007689 name: normal cell growth polarization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cells can grow in a normally (i.e. as in wild type) polarized manner as in the presence of a polarity landmark. The landmark itself may be in a normal or abnormal location." [PMID:21148300, PomBase:mah] comment: The difference between this term and 'normal cell polarity' (FYPO:0005456) is that this term can be used if a polarity landmark is in an abnormal place, but polar growth takes place at the landmark. FYPO:0005465 can be used only when all aspects of polar growth are normal. synonym: "normal cell growth polarisation" EXACT [PomBase:mah] synonym: "normal cell growth polarization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal cell growth polarization during vegetative growth" EXACT [PomBase:mah] synonym: "normal vegetative cell growth polarization" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:16:39Z" xsd:dateTime [Term] id: FYPO:0007690 name: catalytic activity regulator phenotype def: "A phenotype that affects a molecular function which in turn binds to an enzyme and thereby directly regulates its catalytic activity." [GO:0030234, PomBase:mah] synonym: "catalytic activity regulation phenotype" RELATED [PomBase:mah] synonym: "catalytic regulator phenotype" EXACT [GO:0030234] synonym: "enzyme regulator phenotype" EXACT [GO:0030234] is_a: FYPO:0000652 ! molecular function phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:45:32Z" xsd:dateTime [Term] id: FYPO:0007691 name: normal DNA strand exchange activator activity def: "A molecular function phenotype in which the activity of a DNA strand exchange activator is normal (i.e. indistinguishable from wild type)." [PMID:33493431, PomBase:mah] synonym: "normal positive regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "normal RecA-family recombinase activator activity" EXACT [PMID:33493431] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:47:17Z" xsd:dateTime [Term] id: FYPO:0007692 name: increased DNA strand exchange activator activity def: "A molecular function phenotype in which the activity of a DNA strand exchange activator is increased." [PMID:33493431, PomBase:mah] synonym: "increased positive regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "increased RecA-family recombinase activator activity" EXACT [PMID:33493431] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:48:30Z" xsd:dateTime [Term] id: FYPO:0007693 name: decreased DNA strand exchange activator activity def: "A molecular function phenotype in which the activity of a DNA strand exchange activator is decreased." [PMID:33493431, PomBase:mah] synonym: "decreased positive regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "decreased RecA-family recombinase activator activity" EXACT [PMID:33493431] synonym: "reduced DNA strand exchange activator activity" EXACT [PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:50:56Z" xsd:dateTime [Term] id: FYPO:0007694 name: abolished DNA strand exchange activator activity def: "A molecular function phenotype in which the activity of a DNA strand exchange activator is absent." [PMID:33493431, PomBase:mah] synonym: "abolished positive regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "abolished RecA-family recombinase activator activity" EXACT [PMID:33493431] synonym: "DNA strand exchange activator activity abolished" EXACT [PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:51:30Z" xsd:dateTime [Term] id: FYPO:0007695 name: normal DNA strand exchange inhibitor activity def: "A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is normal (i.e. indistinguishable from wild type)." [PMID:33493431, PomBase:mah] synonym: "normal negative regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "normal RecA-family recombinase inhibitor activity" EXACT [PMID:33493431] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:53:41Z" xsd:dateTime [Term] id: FYPO:0007696 name: increased DNA strand exchange inhibitor activity def: "A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is increased." [PMID:33493431, PomBase:mah] synonym: "increased negative regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "increased RecA-family recombinase inhibitor activity" EXACT [PMID:33493431] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:54:03Z" xsd:dateTime [Term] id: FYPO:0007697 name: decreased DNA strand exchange inhibitor activity def: "A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is decreased." [PMID:33493431, PomBase:mah] synonym: "decreased negative regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "decreased RecA-family recombinase inhibitor activity" EXACT [PMID:33493431] synonym: "reduced DNA strand exchange inhibitor activity" EXACT [PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:54:17Z" xsd:dateTime [Term] id: FYPO:0007698 name: abolished DNA strand exchange inhibitor activity def: "A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is absent." [PMID:33493431, PomBase:mah] synonym: "abolished negative regulation of RecA-family recombinase activity" RELATED [PMID:33493431] synonym: "abolished RecA-family recombinase inhibitor activity" EXACT [PMID:33493431] synonym: "DNA strand exchange inhibitor activity abolished" EXACT [PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T14:54:30Z" xsd:dateTime [Term] id: FYPO:0007699 name: decreased frequency of conjugation with non-sister cells def: "A cell population phenotype in which a smaller than normal proportion of cells in a homothallic population undergoes conjugation with non-sister cells." [PMID:30279276, PomBase:mah] synonym: "decreased conjugation frequency with non-sister cells" EXACT [PomBase:mah] synonym: "decreased frequency of mating with non-sister cells" EXACT [PomBase:mah] synonym: "decreased mating efficiency with non-sister cells" RELATED [PMID:30279276] synonym: "decreased mating frequency with non-sister cells" EXACT [PomBase:mah] is_a: FYPO:0000303 ! decreased conjugation frequency property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T15:24:23Z" xsd:dateTime [Term] id: FYPO:0007700 name: inviable small vegetative cell with premature mitotic G2/M phase transition def: "A cell phenotype in which a vegetative cell is inviable and an abnormally low volume, and in which the G2/M transition of the mitotic cell cycle begins earlier than normal." [PMID:1706223, PMID:33683349, PomBase:mah] synonym: "inviable small cell with premature mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with advanced mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "inviable small vegetative cell with advanced mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with advanced mitotic G2/M transition" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with mitotic cell cycle advance at G2/M transition" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with mitotic G2 advance" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with mitotic G2/M transition advance" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with premature cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "inviable small vegetative cell with premature mitotic G2/M phase transition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable small vegetative cell with premature mitotic G2/M transition" EXACT [PomBase:mah] synonym: "mitotic catastrophe" RELATED [PMID:1706223, PMID:33683349, PomBase:vw] is_a: FYPO:0000951 ! inviable small vegetative cell is_a: FYPO:0002516 ! premature mitotic G2/M phase transition property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T15:49:40Z" xsd:dateTime [Term] id: FYPO:0007701 name: inviable elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is longer than normal, has one nucleus, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition." [PMID:33683349, PomBase:mah] synonym: "inviable elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate cell with cell cycle arrest in mitotic G2 phase" RELATED [PomBase:mah] synonym: "inviable elongated mononucleate vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "lethal; elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] is_a: FYPO:0004255 ! inviable elongated mononucleate vegetative cell is_a: FYPO:0007702 ! inviable elongated cell with cell cycle arrest at mitotic G2/M phase transition property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T16:24:04Z" xsd:dateTime [Term] id: FYPO:0007702 name: inviable elongated cell with cell cycle arrest at mitotic G2/M phase transition def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is longer than normal, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition." [PomBase:mah, PomBase:vw] synonym: "classical cdc phenotype" RELATED [PomBase:vw] synonym: "inviable elongated cell with cell cycle arrest at mitotic G2/M phase transition during mitotic cell cycle" RELATED [PomBase:mah] synonym: "inviable elongated cell with cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated cell with cell cycle arrest in mitotic G2 phase" RELATED [PomBase:mah] synonym: "inviable elongated vegetative cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "lethal; elongated cell with cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] is_a: FYPO:0000400 ! abnormal cell cycle arrest at mitotic G2/M phase transition is_a: FYPO:0001497 ! inviable elongated cell with mitotic cell cycle arrest in interphase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T16:28:52Z" xsd:dateTime [Term] id: FYPO:0007703 name: abolished protein localization to lateral cell cortex during glucose starvation def: "A cell phenotype in which the localization of a protein to the cell cortex does not occur when the cell is subject to glucose starvation." [PMID:26443240, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to lateral cell cortex during glucose starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to cell side during glucose starvation" RELATED [PomBase:vw] synonym: "abolished protein localization to lateral cell cortex during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "abolished protein localization to lateral cell cortex during glucose depletion" EXACT [PomBase:mah] synonym: "abolished protein localization to lateral cell cortex during glucose deprivation" EXACT [PomBase:mah] synonym: "abolished protein localization to lateral cortex during glucose starvation" EXACT [PomBase:vw] synonym: "protein localization to lateral cell cortex during glucose starvation abolished" EXACT [PomBase:mah] is_a: FYPO:0001375 ! abolished protein localization is_a: FYPO:0007869 ! abnormal protein localization to lateral cell cortex property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T16:30:37Z" xsd:dateTime [Term] id: FYPO:0007704 name: decreased protein localization to lateral cell cortex during glucose starvation def: "A cell phenotype in which the localization of a protein to the cell cortex is decreased when the cell is subject to glucose starvation." [PMID:26443240, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to lateral cell cortex during glucose starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to cell side during glucose starvation" RELATED [PomBase:vw] synonym: "decreased protein localization to lateral cell cortex during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "decreased protein localization to lateral cell cortex during glucose depletion" EXACT [PomBase:mah] synonym: "decreased protein localization to lateral cell cortex during glucose deprivation" EXACT [PomBase:mah] synonym: "decreased protein localization to lateral cortex during glucose starvation" EXACT [PomBase:vw] synonym: "reduced protein localization to lateral cell cortex during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0007869 ! abnormal protein localization to lateral cell cortex property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T16:34:20Z" xsd:dateTime [Term] id: FYPO:0007705 name: normal protein localization to lateral cell cortex during glucose starvation def: "A cell phenotype in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type) when the cell is subject to glucose starvation." [PMID:26443240, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to lateral cell cortex during glucose starvation" EXACT [PomBase:mah] synonym: "normal protein localization to cell side during glucose starvation" RELATED [PomBase:vw] synonym: "normal protein localization to lateral cell cortex during cellular response to glucose starvation" EXACT [PomBase:mah] synonym: "normal protein localization to lateral cell cortex during glucose depletion" EXACT [PomBase:mah] synonym: "normal protein localization to lateral cell cortex during glucose deprivation" EXACT [PomBase:mah] synonym: "normal protein localization to lateral cortex during glucose starvation" EXACT [PomBase:vw] is_a: FYPO:0003627 ! normal protein localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T16:35:31Z" xsd:dateTime [Term] id: FYPO:0007706 name: decreased microtubule depolymerization at cell side def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the removal of tubulin dimers from a microtubule occurs to a lower extent than normal in the lateral part of the cell." [PMID:26443240, PomBase:mah] synonym: "decreased microtubule catastrophe at cell side" RELATED [PomBase:mah] synonym: "decreased microtubule depolymerisation at cell side" EXACT [PomBase:mah] synonym: "decreased microtubule depolymerization at cell side during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased microtubule depolymerization at cell side during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule depolymerization at lateral part of cell" EXACT [PomBase:mah] synonym: "reduced microtubule depolymerization at cell side" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-23T16:59:47Z" xsd:dateTime [Term] id: FYPO:0007707 name: decreased GTPase activator activity def: "A molecular function phenotype in which the activity of a GTPase activator is decreased." [PMID:30279276, PomBase:mah] synonym: "decreased GAP activity" EXACT [GO:0005096] synonym: "reduced GTPase activator activity" EXACT [PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-30T13:59:48Z" xsd:dateTime [Term] id: FYPO:0007708 name: normal dynamic protein localization to cell tip def: "A cell phenotype in which a protein that is normally dynamically localized to one or both cell tips shows a normal (i.e. indistinguishable from wild type) temporal pattern of localization. For example, a protein may move from one cell tip to the other at a normal frequency and amplitude." [PMID:30279276, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal dynamic protein localization to cell end" EXACT [PomBase:mah] synonym: "normal dynamic protein localization to cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal dynamic protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "normal oscillatory protein localization to cell tip" NARROW [PomBase:mah] is_a: FYPO:0006999 ! normal dynamic protein localization pattern property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-30T14:05:47Z" xsd:dateTime [Term] id: FYPO:0007709 name: decreased protein localization to cell cortex of non-growing cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of a non-growing cell tip is decreased." [PMID:23093943, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell cortex of non-growing cell tip" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex of new non-growing cell tip" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex of non-growing cell end" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex of non-growing cell tip during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to cell cortex of non-growing cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to non-growing cell tip cortex" EXACT [PomBase:mah] synonym: "reduced protein localization to cell cortex of non-growing cell tip" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-30T14:20:08Z" xsd:dateTime [Term] id: FYPO:0007710 name: decreased number of Ssb1 foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Ssb1 accumulates is lower than normal." [PMID:33723569, PomBase:mah] synonym: "decreased number of Rad11 foci" EXACT [PomBase:mah] synonym: "decreased number of RPA foci" EXACT [PomBase:mah] synonym: "decreased number of Rpa1 foci" EXACT [PomBase:mah] synonym: "decreased number of Ssb1 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased number of Ssb1 foci during vegetative growth" EXACT [PomBase:mah] synonym: "reduced number of Ssb1 foci" EXACT [PomBase:mah] is_a: FYPO:0004639 ! abnormal cellular physical quality phenotype during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-30T14:34:04Z" xsd:dateTime [Term] id: FYPO:0007711 name: normal number of Ssb1 foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Ssb1 accumulates normal (i.e. indistinguishable from wild type)." [PMID:33723569, PomBase:mah] synonym: "normal number of Rad11 foci" EXACT [PomBase:mah] synonym: "normal number of RPA foci" EXACT [PomBase:mah] synonym: "normal number of Rpa1 foci" EXACT [PomBase:mah] synonym: "normal number of Ssb1 foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal number of Ssb1 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007723 ! normal cellular physical quality phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-03-30T14:42:20Z" xsd:dateTime [Term] id: FYPO:0007712 name: mitochondria absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain any detectable mitochondria." [PMID:33483504, PomBase:mah] synonym: "absent mitochondria" EXACT [PomBase:mah] synonym: "mitochondria absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "mitochondria absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrion absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T12:40:21Z" xsd:dateTime [Term] id: FYPO:0007713 name: large ERMES foci present in decreased numbers def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, ERMES foci than normal. An ERMES focus is a site that contains one or more ERMES complex(es)." [PMID:33483504, PomBase:mah] synonym: "enlarged ERMES foci present in decreased numbers" EXACT [PomBase:mah] synonym: "large ERMES foci present in decreased numbers during mitotic cell cycle" RELATED [PomBase:mah] synonym: "large ERMES foci present in decreased numbers during vegetative growth" EXACT [PomBase:mah] synonym: "large ERMES foci present in reduced numbers" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T12:41:39Z" xsd:dateTime [Term] id: FYPO:0007714 name: decreased mitochondrial phosphatidylethanolamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in the mitochondrion differs from normal." [PMID:33483504, PomBase:mah] synonym: "decreased mitochondrial PE level" EXACT [PomBase:mah] synonym: "decreased mitochondrial phosphatidylethanolamine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial phosphatidylethanolamine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased phosphatidylethanolamine in mitochondria" EXACT [PomBase:vw] synonym: "decreased phosphatidylethanolamine level in mitochondria" EXACT [PomBase:mah] synonym: "reduced mitochondrial phosphatidylethanolamine level" EXACT [PomBase:mah] is_a: FYPO:0004957 ! altered level of substance in mitochondrion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T12:51:59Z" xsd:dateTime [Term] id: FYPO:0007715 name: decreased mitochondrial phosphatidylserine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in the mitochondrion differs from normal." [PMID:33483504, PomBase:mah] synonym: "decreased mitochondrial phosphatidylserine level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased mitochondrial phosphatidylserine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitochondrial PS level" EXACT [PomBase:mah] synonym: "decreased phosphatidylserine in mitochondria" EXACT [PomBase:vw] synonym: "decreased phosphatidylserine level in mitochondria" EXACT [PomBase:mah] synonym: "reduced mitochondrial phosphatidylserine level" EXACT [PomBase:mah] is_a: FYPO:0004957 ! altered level of substance in mitochondrion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T12:53:26Z" xsd:dateTime [Term] id: FYPO:0007716 name: resistance to tebuconazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tebuconazole than normal." [PomBase:mah] synonym: "resistance to tebuconazole during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to tebuconazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tebuconazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T12:59:23Z" xsd:dateTime created_by: midori creation_date: 2018-11-06T14:47:00Z [Term] id: FYPO:0007717 name: sensitive to potassium nitrate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium chloride. Cells stop growing (and may die) at a concentration of potassium nitrate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to potassium nitrate" EXACT [PomBase:mah] synonym: "sensitive to KNO3" EXACT [PomBase:mah] synonym: "sensitive to potassium nitrate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to potassium nitrate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T13:14:19Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007718 name: abnormal SMN complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which SMN complex assembly is abnormal." [PomBase:mah] synonym: "abnormal SMN complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal SMN complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein-containing complex assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T13:46:01Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007719 name: abolished SMN complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which SMN complex assembly is abolished." [PMID:33754639, PomBase:mah] synonym: "abolished SMN complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished SMN complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "SMN complex assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0007718 ! abnormal SMN complex assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T14:00:25Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007720 name: decreased SMN complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of SMN complex assembly is decreased." [PMID:33754639, PomBase:mah] synonym: "decreased SMN complex assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased SMN complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced SMN complex assembly" EXACT [PomBase:mah] is_a: FYPO:0007718 ! abnormal SMN complex assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T14:01:55Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007721 name: abnormal protein recycling from late endosome to Golgi def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of proteins via vesicles from late endosomes to the Golgi is abnormal. This process is normally mediated by the retromer complex." [PMID:33788833, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein recycling from endosome to Golgi by retromer" EXACT [PomBase:mah] synonym: "abnormal protein recycling from late endosome to Golgi during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein recycling from late endosome to Golgi during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal retromer-mediated protein recycling from endosome to Golgi" EXACT [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-12T14:27:04Z" xsd:dateTime [Term] id: FYPO:0007722 name: decreased nucleosome-dependent ATPase activity def: "A molecular function phenotype in which the observed rate of nucleosome-dependent ATPase activity is decreased." [PomBase:mah] synonym: "reduced nucleosome-dependent ATPase activity" EXACT [PomBase:mah] is_a: FYPO:0005519 ! abnormal nucleosome-dependent ATPase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-13T11:32:38Z" xsd:dateTime [Term] id: FYPO:0007723 name: normal cellular physical quality phenotype def: "A phenotype in which a physical object quality, such as morphology, number, location, etc., of a cell or a cellular component is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular physical object quality" EXACT [PATO:0001241] is_a: FYPO:0000136 ! cellular physical quality phenotype is_a: FYPO:0000257 ! normal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-13T11:51:10Z" xsd:dateTime [Term] id: FYPO:0007724 name: normal ERMES foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the ERMES foci in a cell are normal (i.e. indistinguishable from wild type) in number, size, and distribution. An ERMES focus is a site that contains one or more ERMES complex(es)." [PMID:33483504, PomBase:mah] synonym: "normal ERMES foci during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal ERMES foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0007723 ! normal cellular physical quality phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-13T11:57:21Z" xsd:dateTime [Term] id: FYPO:0007725 name: normal protein localization to late endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to late endosome" EXACT [PomBase:mah] synonym: "normal protein localization to late endosome during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to late endosome during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to prevacuolar compartment" EXACT [GO:0005770] synonym: "normal protein localization to prevacuolar endosome" EXACT [PomBase:vw] synonym: "normal protein localization to PVE" EXACT [PomBase:vw] is_a: FYPO:0000644 ! normal protein localization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-19T14:56:57Z" xsd:dateTime [Term] id: FYPO:0007726 name: decreased cell population growth on phenylalanine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-phenylalanine as the nitrogen source." [PomBase:mah] synonym: "decreased growth on phenylalanine nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on phenylalanine nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth with phenylalanine nitrogen source" RELATED [PomBase:mah] synonym: "reduced cell growth on phenylalanine nitrogen source" RELATED [PomBase:mah] synonym: "slow cell growth on phenylalanine nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-19T15:06:22Z" xsd:dateTime [Term] id: FYPO:0007727 name: abnormal late endosome morphology def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of late endosomes is abnormal." [PomBase:mah] synonym: "abnormal late endosome morphology during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal late endosome morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal prevacuolar compartment morphology" EXACT [GO:0005770] synonym: "abnormal prevacuolar endosome morphology" EXACT [PomBase:vw] synonym: "abnormal PVE morphology" EXACT [PomBase:vw] is_a: FYPO:0000353 ! abnormal endomembrane system morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-19T15:26:24Z" xsd:dateTime [Term] id: FYPO:0007728 name: normal protein kinase activity during cellular response to osmotic stress def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to osmotic stress." [PMID:33137119, PomBase:mah] is_a: FYPO:0003075 ! normal protein kinase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-19T15:28:37Z" xsd:dateTime [Term] id: FYPO:0007729 name: decreased protein localization to mitotic spindle during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is decreased during anaphase." [PMID:16920624, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to mitotic spindle during anaphase" EXACT [PomBase:mah] synonym: "decreased protein localization to elongating mitotic spindle" RELATED [PomBase:vw] synonym: "decreased protein localization to mitotic spindle during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle during anaphase of mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to spindle during mitotic anaphase" EXACT [PomBase:mah] synonym: "reduced protein localization to mitotic spindle during anaphase" EXACT [PomBase:mah] is_a: FYPO:0002825 ! decreased protein localization to mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-19T15:31:15Z" xsd:dateTime [Term] id: FYPO:0007730 name: normal protein distribution along RNA polymerase II-transcribed genes during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type) during metaphase of the mitotic cell cycle." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein distribution across RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-regulated genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-transcribed genes during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein distribution along RNA polymerase II-transcribed genes during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein distribution in chromatin along RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin along RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0006021 ! normal protein distribution along RNA polymerase II-transcribed genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T13:53:53Z" xsd:dateTime [Term] id: FYPO:0007731 name: normal protein localization to chromatin at 3' end of genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes is normal (i.e. indistinguishable from wild type)." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal condensin localization to chromatin at 3' end of genes" NARROW [PomBase:vw] synonym: "normal protein localisation to chromatin at 3' end of genes" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at 3' end of genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to chromatin at 3' end of genes during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin downstream of genes" EXACT [PomBase:vw] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T13:55:51Z" xsd:dateTime [Term] id: FYPO:0007732 name: normal protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase III is normal (i.e. indistinguishable from wild type) during metaphase of the mitotic cell cycle." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal condensin localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase" NARROW [PomBase:vw] synonym: "normal protein localisation to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin downstream of RNA polymerase III-transcribed genes during mitotic metaphase" EXACT [PomBase:vw] is_a: FYPO:0007731 ! normal protein localization to chromatin at 3' end of genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T14:00:09Z" xsd:dateTime [Term] id: FYPO:0007733 name: abnormal protein localization to chromatin at 3' end of genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes is abnormal." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal condensin localization to chromatin at 3' end of genes" NARROW [PomBase:vw] synonym: "abnormal protein localisation to chromatin at 3' end of genes" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromatin at 3' end of genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal protein localization to chromatin at 3' end of genes during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromatin downstream of genes" EXACT [PomBase:vw] is_a: FYPO:0007465 ! altered spatial extent of protein localization to chromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T14:12:17Z" xsd:dateTime [Term] id: FYPO:0007734 name: increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase III is increased." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased condensin localization to chromatin at 3' end of RNA polymerase III-transcribed genes" NARROW [PomBase:vw] synonym: "increased protein localisation to chromatin at 3' end of RNA polymerase III-transcribed genes" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin downstream of RNA polymerase III-transcribed genes" EXACT [PomBase:vw] is_a: FYPO:0007733 ! abnormal protein localization to chromatin at 3' end of genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T14:17:23Z" xsd:dateTime [Term] id: FYPO:0007735 name: increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase III is increased during metaphase of the mitotic cell cycle." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased condensin localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase" NARROW [PomBase:vw] synonym: "increased protein localisation to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "increased protein localization to chromatin downstream of RNA polymerase III-transcribed genes during mitotic metaphase" EXACT [PomBase:vw] is_a: FYPO:0007734 ! increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T14:18:52Z" xsd:dateTime [Term] id: FYPO:0007736 name: protein displaced from 3' end to 5' end of RNA polymerase II-transcribed genes during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is altered such that more of the protein is present at the 5' end, and less at the 3' end, than normal during metaphase of the mitotic cell cycle." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "condensin displaced from 3' end to 5' end of RNA polymerase II-transcribed genes during mitotic metaphase" NARROW [PomBase:vw] synonym: "decreased protein localization to chromatin at 3' end of RNA polymerase II-transcribed genes during metaphase with increased localization towards 5' end" EXACT [PomBase:vw] synonym: "protein displaced from 3' end to 5' end of RNA polymerase II-transcribed genes during mitotic metaphase during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein displaced from 3' end to 5' end of RNA polymerase II-transcribed genes during mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "protein displaced from downstream end to 5' end of RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:vw] is_a: FYPO:0006020 ! abnormal protein distribution along RNA polymerase II-transcribed genes is_a: FYPO:0007733 ! abnormal protein localization to chromatin at 3' end of genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T14:19:52Z" xsd:dateTime [Term] id: FYPO:0007737 name: increased mitochondrial membrane potential def: "A physical cellular phenotype in which the mitochondrial membrane potential, i.e. the electric potential existing across the mitochondrial membrane, is greater than normal." [GO:0051881, PMID:33823662, PomBase:mah] synonym: "increased mitochondrial membrane polarization" EXACT [PomBase:mah] synonym: "increased mitochondrial membrane potential during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased mitochondrial membrane potential during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial membrane hyperpolarization" RELATED [PomBase:mah] is_a: FYPO:0004943 ! abnormal mitochondrion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-21T14:22:01Z" xsd:dateTime [Term] id: FYPO:0007738 name: normal protein localization to chromatin at 3' end of RNA polymerase II-transcribed genes during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type) during metaphase of the mitotic cell cycle." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal condensin localization to chromatin at 3' end of RNA polymerase II-transcribed genes during mitotic metaphase" BROAD [PomBase:vw] synonym: "normal protein localisation to chromatin at 3' end of RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at 3' end of RNA polymerase II-transcribed genes during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin at 3' end of RNA polymerase II-transcribed genes during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin downstream of RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:vw] is_a: FYPO:0007731 ! normal protein localization to chromatin at 3' end of genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-26T14:39:43Z" xsd:dateTime [Term] id: FYPO:0007739 name: delayed onset of nucleolar ring disassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar ring disassembly begins later than normal. Nucleolar rings are structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress. They normally disassemble upon removal of heat stress." [PMID:33176152, PomBase:mah] synonym: "delayed nucleolar ring disassembly" EXACT [PomBase:mah] synonym: "delayed nucleolar ring disassembly during recovery from heat shock" EXACT [PMID:33176152] synonym: "delayed onset of nucleolar ring disassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of nucleolar ring disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of NuR disassembly" EXACT [PMID:33176152] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-26T14:54:06Z" xsd:dateTime [Term] id: FYPO:0007740 name: normal nucleolar ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar ring assembly is normal (i.e. indistinguishable from wild type). Nucleolar rings are structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress." [PMID:33176152, PomBase:mah] synonym: "normal nucleolar ring assembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal nucleolar ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal NuR assembly" EXACT [PMID:33176152] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-04-26T14:55:54Z" xsd:dateTime [Term] id: FYPO:0007741 name: abnormal protein distribution along RNA polymerase II-transcribed genes during mitotic metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is abnormal during metaphase of the mitotic cell cycle." [PMID:33771877, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein distribution across RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "abnormal protein distribution along RNA polymerase II-regulated genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "abnormal protein distribution along RNA polymerase II-transcribed genes during metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein distribution along RNA polymerase II-transcribed genes during metaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal protein distribution in chromatin along RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromatin along RNA polymerase II-transcribed genes during mitotic metaphase" EXACT [PomBase:mah] is_a: FYPO:0006020 ! abnormal protein distribution along RNA polymerase II-transcribed genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-05T10:20:40Z" xsd:dateTime [Term] id: FYPO:0007742 name: premature actomyosin contractile ring assembly during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring assembly begins during interphase of the mitotic cell cycle. Contractile ring assembly normally begins during M phase." [PMID:20226666, PomBase:mah] synonym: "advanced actomyosin contractile ring assembly during mitotic interphase" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring assembly during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring assembly during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature actomyosin contractile ring formation during mitotic interphase" RELATED [PomBase:mah] synonym: "premature contractile ring assembly during mitotic interphase" EXACT [PomBase:vw] synonym: "premature cytokinetic contractile ring assembly during mitotic interphase" EXACT [PomBase:vw] synonym: "premature mitotic actomyosin contractile ring assembly during mitotic interphase" EXACT [PomBase:mah] synonym: "premature mitotic contractile ring assembly during mitotic interphase" EXACT [PomBase:vw] is_a: FYPO:0007211 ! premature actomyosin contractile ring assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-05T10:49:23Z" xsd:dateTime [Term] id: FYPO:0007743 name: premature septum assembly during mitotic interphase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly begins during interphase of the mitotic cell cycle. Septum assembly normally begins during M phase." [PMID:20226666, PomBase:mah] synonym: "advanced septum assembly during mitotic interphase" EXACT [PomBase:mah] synonym: "premature division septum assembly during mitotic interphase" EXACT [GO:0000917, PomBase:mah] synonym: "premature septation" BROAD [GO:0000917, PomBase:mah] synonym: "premature septum assembly during interphase during vegetative growth" EXACT [PomBase:mah] synonym: "premature septum assembly during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "premature septum formation during mitotic interphase" RELATED [PomBase:mah] is_a: FYPO:0003250 ! premature septum assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-05T10:51:19Z" xsd:dateTime [Term] id: FYPO:0007744 name: spindle collapse during meiotic prophase I def: "A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but does not elongate normally or completely, and collapses during prophase I. Upon collapse the spindle may break or shrink." [PMID:32723864, PomBase:mah] synonym: "broken meiotic spindle during prophase I" RELATED [PomBase:vw] synonym: "meiotic spindle breakage during prophase I" EXACT [PomBase:mah] synonym: "spindle collapse during prophase I of meiotic cell cycle" RELATED [PomBase:mah] synonym: "spindle collapse during prophase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0007103 ! spindle collapse during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:28:16Z" xsd:dateTime [Term] id: FYPO:0007745 name: abnormal spindle assembly during meiosis I def: "A cellular process phenotype in which assembly of the meiotic spindle is abnormal during the first meiotic nuclear division." [PMID:32723864, PomBase:mah] synonym: "abnormal meiosis I spindle assembly" EXACT [PomBase:mah] synonym: "abnormal meiosis I spindle formation" EXACT [PomBase:vw] synonym: "abnormal meiotic spindle assembly during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0000737 ! abnormal meiotic spindle assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:32:09Z" xsd:dateTime [Term] id: FYPO:0007746 name: normal spindle elongation during meiotic metaphase I def: "A cellular process phenotype in which the spindle elongates during metaphase of the first meiotic nuclear division, when elongation is normally paused." [PMID:32723864, PomBase:mah] synonym: "normal spindle elongation during meiotic metaphase I spindle phase II" EXACT [PomBase:vw] synonym: "normal spindle elongation during metaphase I" EXACT [PomBase:mah] synonym: "normal spindle elongation during metaphase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0007745 ! abnormal spindle assembly during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:33:55Z" xsd:dateTime [Term] id: FYPO:0007747 name: normal meiotic spindle length during prophase I def: "A physical cellular phenotype in which the length of the meiotic spindle is normal (i.e. indistinguishable from wild type) during prophase I." [PMID:32723864, PomBase:mah] synonym: "normal spindle length during meiotic prophase I" EXACT [PomBase:mah] synonym: "normal spindle length during prophase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component relationship: part_of FYPO:0004569 ! normal spindle during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:37:10Z" xsd:dateTime [Term] id: FYPO:0007748 name: increased duration of spindle assembly during meiosis I def: "A cellular process phenotype in which the duration of spindle assembly during meiosis I is longer than normal. The total duration of spindle phases I (initial assembly and first stage of elongation) and II (in which elongation normally pauses, and which coincides with metaphase I) is increased due to prolongation of either or both phases." [PMID:32723864, PomBase:mah] synonym: "increased duration of meiosis I spindle assembly" EXACT [PomBase:mah] synonym: "increased duration of meiosis I spindle formation" EXACT [PomBase:mah] synonym: "increased duration of meiotic spindle assembly during meiosis I" EXACT [PomBase:mah] synonym: "increased duration of meiotic spindle formation during meiosis I" EXACT [PomBase:mah] synonym: "increased duration of spindle assembly phase I and II during meiosis I" EXACT [PomBase:vw] synonym: "prolonged meiosis I spindle assembly" EXACT [PomBase:mah] synonym: "prolonged meiosis I spindle formation" EXACT [PomBase:mah] synonym: "prolonged meiosis I spindle formation phase I and II" EXACT [PomBase:vw] synonym: "prolonged meiosis I spindle phase I and II" EXACT [PomBase:vw] synonym: "prolonged meiotic spindle assembly during meiosis I" EXACT [PomBase:mah] synonym: "prolonged meiotic spindle formation during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0007745 ! abnormal spindle assembly during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:43:10Z" xsd:dateTime [Term] id: FYPO:0007749 name: decreased protein localization to meiotic spindle during meiosis I def: "A cellular process phenotype in which the localization of a protein to the spindle is decreased during the first meiotic nuclear division." [PMID:32723864, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "decreased protein localization to meiosis I spindle" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle during meiosis I" EXACT [PomBase:mah] synonym: "reduced protein localization to meiotic spindle during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:47:20Z" xsd:dateTime [Term] id: FYPO:0007750 name: normal protein localization to meiotic spindle during meiosis I def: "A cellular process phenotype in which the localization of a protein to the spindle is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division." [PMID:32723864, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to spindle during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to meiosis I spindle" EXACT [PomBase:mah] synonym: "normal protein localization to spindle during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007866 ! normal protein localization to meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:47:20Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T13:48:56Z" xsd:dateTime [Term] id: FYPO:0007751 name: spindle collapse during meiotic prometaphase I def: "A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but does not elongate normally or completely, and collapses during prometaphase I. Upon collapse the spindle may break or shrink." [PMID:32723864, PomBase:mah] synonym: "broken meiotic spindle during prometaphase I" RELATED [PomBase:vw] synonym: "meiosis I spindle collapse during prometaphase" EXACT [PomBase:vw] synonym: "meiotic spindle breakage during prometaphase I" EXACT [PomBase:mah] synonym: "meiotic spindle collapse during prometaphase I" EXACT [PomBase:mah] synonym: "spindle collapse during prometaphase I" EXACT [PomBase:mah] synonym: "spindle collapse during prometaphase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0007103 ! spindle collapse during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:07:10Z" xsd:dateTime [Term] id: FYPO:0007752 name: spindle regression during meiosis I def: "A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but then become shorter instead of continuing or resuming elongation." [PMID:32723864, PomBase:mah] synonym: "meiosis I spindle regression" EXACT [PomBase:vw] synonym: "meiosis I spindle shrinkage" EXACT [PomBase:vw] synonym: "meiotic spindle regression during meiosis I" EXACT [PomBase:mah] synonym: "spindle regression during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "spindle shrinkage during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0003603 ! abnormal meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:09:08Z" xsd:dateTime [Term] id: FYPO:0007753 name: multiple spindles during meiosis I def: "A physical cellular phenotype in which a cell contains more than one meiotic spindle during the first meiotic nuclear division." [PMID:32723864, PomBae:mah] synonym: "additional spindles present during meiosis I" EXACT [PomBase:mah] synonym: "extra spindles during meiosis I" EXACT [PomBase:mah] synonym: "increased number of spindles during meiosis I" EXACT [PomBase:mah] synonym: "multiple meiotic spindles during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "multiple meiotic spindles during meiosis I" EXACT [PomBase:mah] synonym: "spindles present in greater numbers during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0006390 ! multiple meiotic spindles property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:10:23Z" xsd:dateTime [Term] id: FYPO:0007754 name: abolished mitotic spindle formation phase II def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which phase II of mitotic spindle assembly does not occur. During phase II, the spindle is normally maintained at a constant length during mitotic metaphase." [PMID:32723864, PomBase:mah] synonym: "abnormal mitotic spindle formation, without spindle phase II" EXACT [PomBase:vw] synonym: "abolished mitotic spindle assembly phase II" EXACT [PomBase:mah] synonym: "abolished mitotic spindle formation (spindle phase two)" EXACT [GO:0140641] is_a: FYPO:0000177 ! abnormal mitotic spindle assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:11:42Z" xsd:dateTime [Term] id: FYPO:0007755 name: short meiotic spindle during metaphase I def: "A physical cellular phenotype in which the spindle is shorter than normal during metaphase of meiosis I." [PMID:32723864, PomBase:mah] synonym: "short meiosis I spindle during metaphase" EXACT [PomBase:mah] synonym: "short spindle during meiotic metaphase I" EXACT [PomBase:mah] synonym: "short spindle during metaphase of meiosis I" EXACT [PomBase:mah] is_a: FYPO:0000735 ! short meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:23:37Z" xsd:dateTime [Term] id: FYPO:0007756 name: abnormal homologous chromosome segregation with collapsed spindle def: "A cell phenotype in which homologous chromosome segregation is abnormal, and the meiotic spindle collapses." [PMID:32723864, PomBase:mah] synonym: "abnormal chromosome disjunction at meiosis I with collapsed spindle" EXACT [PomBase:vw] synonym: "abnormal chromosome segregation during meiosis I with collapsed spindle" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome disjunction with collapsed spindle" EXACT [PomBase:vw] synonym: "abnormal homologous chromosome segregation with collapsed spindle during meiosis I" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome segregation with meiosis I spindle collapse" EXACT [PomBase:mah] synonym: "abnormal homologous chromosome segregation with spindle collapse" EXACT [PomBase:mah] synonym: "chromosome missegregation with collapsed spindle during meiosis I" RELATED [PomBase:vw] synonym: "homologous chromosome missegregation with collapsed spindle" RELATED [PomBase:vw] synonym: "meiotic chromosome missegregation with collapsed spindle" RELATED [PomBase:vw] is_a: FYPO:0003603 ! abnormal meiosis I is_a: FYPO:0004159 ! abnormal homologous chromosome segregation relationship: has_part FYPO:0007083 ! meiotic spindle collapse property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:25:44Z" xsd:dateTime [Term] id: FYPO:0007757 name: normal protein localization to new mitotic spindle pole body during anaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the new mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during anaphase." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal asymmetric protein localization to new mitotic spindle pole body during anaphase" EXACT [GO:0061510] synonym: "normal protein localisation to new mitotic spindle pole body during anaphase" EXACT [PomBase:mah] synonym: "normal protein localization to new mitotic SPB during anaphase" EXACT [PomBase:mah] synonym: "normal protein localization to new mitotic spindle pole body during anaphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "normal protein localization to new spindle pole body during anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein localization to new spindle pole body during mitotic anaphase" EXACT [PomBase:mah] is_a: FYPO:0003330 ! normal protein localization to new mitotic spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-11T15:37:05Z" xsd:dateTime [Term] id: FYPO:0007758 name: increased duration of mitotic sister chromatid cohesion def: "A cellular process phenotype in which mitotic sister chromatid cohesion lasts longer than normal, continuing into anaphase of mitosis." [PMID:33888556, PomBase:mah] synonym: "ectopic cohesion protection during mitosis" RELATED [PMID:33888556] synonym: "increased duration of mitotic chromosome cohesion" EXACT [PomBase:mah] synonym: "increased duration of mitotic sister chromatid cohesion during mitotic anaphase" EXACT [PomBase:mah] synonym: "increased duration of mitotic sister chromatid cohesion during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of mitotic sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "persistent mitotic sister chromatid cohesion during mitotic anaphase" EXACT [PomBase:vw] synonym: "prolonged mitotic sister chromatid cohesion" EXACT [PomBase:mah] is_a: FYPO:0006521 ! abnormal mitotic sister chromatid cohesion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T12:48:17Z" xsd:dateTime [Term] id: FYPO:0007759 name: increased duration of meiotic sister chromatid cohesion at centromere during meiosis I def: "A cellular process phenotype in which cohesion between sister chromatids lasts longer than normal in centromeric regions, continuing into anaphase of the first meiotic nuclear division." [PMID:33888556, PomBase:mah] synonym: "ectopic meiotic sister chromatid cohesion at centromere during meiosis I" RELATED [PMID:33888556] synonym: "increased duration of meiotic sister chromatid cohesion at centromere during anaphase I" EXACT [PomBase:vw] synonym: "increased duration of meiotic sister chromatid cohesion at centromere during anaphase of meiosis I" NARROW [PomBase:mah] synonym: "increased duration of meiotic sister chromatid cohesion at centromere during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "increased duration of meiotic sister chromatid cohesion, centromeric, during meiosis I" EXACT [GO:0051754] synonym: "increased duration of sister chromatid cohesion at centromere during meiosis I" EXACT [PomBase:mah] synonym: "prolonged meiotic sister chromatid cohesion at centromere during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0002092 ! abnormal meiotic sister chromatid cohesion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T13:01:50Z" xsd:dateTime [Term] id: FYPO:0007760 name: decreased protein localization to kinetochore during meiotic prophase II def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is decreased during prophase of the second meiotic nuclear division." [PMID:33888556, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to kinetochore during prophase II" EXACT [PomBase:mah] synonym: "decreased protein localization to kinetochore during meiosis II prophase" EXACT [PomBase:vw] synonym: "decreased protein localization to kinetochore during prophase of meiosis II" EXACT [PomBase:mah] synonym: "reduced protein localization to kinetochore during prophase II" EXACT [PomBase:mah] is_a: FYPO:0004762 ! abnormal protein localization to kinetochore during meiosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T13:32:25Z" xsd:dateTime [Term] id: FYPO:0007761 name: normal protein phosphorylation during mitotic G2/M transition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during the G2/M phase transition of the mitotic cell cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein phosphorylation during G2/M phase transition" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during G2/M transition of mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein phosphorylation during mitotic G2/M transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T14:29:05Z" xsd:dateTime [Term] id: FYPO:0007762 name: abnormal phosphatidate cytidylyltransferase activity def: "A molecular function phenotype in which the observed rate of phosphatidate cytidylyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal CDP-diacylglycerol synthase activity" EXACT [GO:0004605] is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T14:40:04Z" xsd:dateTime [Term] id: FYPO:0007763 name: decreased phosphatidate cytidylyltransferase activity def: "A molecular function phenotype in which the observed rate of phosphatidate cytidylyltransferase activity is decreased." [PomBase:mah] synonym: "decreased CDP-diacylglycerol synthase activity" EXACT [GO:0004605] synonym: "reduced CDP-diacylglycerol synthase activity" EXACT [PomBase:mah] synonym: "reduced phosphatidate cytidylyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0007762 ! abnormal phosphatidate cytidylyltransferase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T14:41:02Z" xsd:dateTime [Term] id: FYPO:0007764 name: enlarged lipid droplets surrounded by endoplasmic reticulum def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which lipid droplets are larger than normal, and are surrounded by endoplasmic reticulum. Fewer droplets than normal may be present." [PMID:25318672, PomBase:mah] synonym: "enlarged lipid droplets surrounded by endoplasmic reticulum during mitotic cell cycle" RELATED [PomBase:mah] synonym: "enlarged lipid droplets surrounded by endoplasmic reticulum during vegetative growth" EXACT [PomBase:mah] synonym: "enlarged lipid droplets surrounded by ER" EXACT [PomBase:mah] synonym: "large lipid droplets surrounded by endoplasmic reticulum" EXACT [PomBase:mah] is_a: FYPO:0000356 ! abnormal lipid droplet morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T14:43:06Z" xsd:dateTime [Term] id: FYPO:0007765 name: abnormal protein level oscillation during mitotic cell cycle def: "A gene expression phenotype in which protein levels that normally vary over the course of the mitotic cell cycle do not vary, or change in a pattern different from normal. Total protein or a specific protein may be affected." [PMID:9430640, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal periodic protein expression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abnormal protein level fluctuation during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0001985 ! abnormal phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T14:54:43Z" xsd:dateTime [Term] id: FYPO:0007766 name: abolished protein level oscillation during mitotic cell cycle def: "A gene expression phenotype in which protein levels that normally vary over the course of the mitotic cell cycle do not vary. Total protein or a specific protein may be affected." [PMID:9430640, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished periodic protein expression during mitotic cell cycle" EXACT [PomBase:mah] synonym: "abolished protein level fluctuation during mitotic cell cycle" EXACT [PomBase:mah] synonym: "protein level oscillation abolished during mitotic cell cycle" EXACT [PomBase:mah] is_a: FYPO:0007765 ! abnormal protein level oscillation during mitotic cell cycle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-13T14:56:11Z" xsd:dateTime [Term] id: FYPO:0007767 name: decreased thiabendazole binding def: "A molecular function phenotype in which occurrence of thiabendazole binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:33925026, PomBase:mah] synonym: "decreased TBZ binding" EXACT [PomBase:mah] synonym: "reduced TBZ binding" EXACT [PomBase:mah] synonym: "reduced thiabendazole binding" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-05-20T15:02:23Z" xsd:dateTime [Term] id: FYPO:0007768 name: abnormal heterochromatin tethering at nuclear periphery def: "A cellular process phenotype in which heterochromatin tethering at the nuclear periphery is abnormal. Normally, heterochromatic parts of chromosomes, such as centromeres and telomeres, are maintained at the nuclear periphery by tethering to the nuclear envelope during all or part of the cell cycle." [PomBase:mah] comment: See GO:0072766, GO:0034398, and GO:0120109. synonym: "abnormal heterochromatin localization to nuclear periphery" RELATED [PomBase:mah] is_a: FYPO:0008383 ! chromosome region localization phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T12:53:02Z" xsd:dateTime [Term] id: FYPO:0007769 name: increased heterochromatin tethering at nuclear periphery during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin tethering at the nuclear periphery persists after the onset of mitosis. Normally, heterochromatic parts of chromosomes, such as centromeres and telomeres, are maintained at the nuclear periphery during interphase and released during mitosis." [PMID:32109380, PomBase:mah] synonym: "increased heterochromatin anchoring at nuclear periphery during mitosis" EXACT [PomBase:vw] synonym: "increased heterochromatin tethering at nuclear periphery during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased heterochromatin tethering at nuclear periphery during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased heterochromatin tethering at nuclear periphery during mitotic M phase" RELATED [PomBase:mah] synonym: "increased heterochromatin tethering at nuclear periphery during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0007768 ! abnormal heterochromatin tethering at nuclear periphery property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T13:02:44Z" xsd:dateTime [Term] id: FYPO:0007770 name: increased telomere tethering at nuclear periphery during mitosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery persists after the onset of mitosis. Normally, telomeres are maintained at the nuclear periphery during interphase and released during mitosis." [PMID:32109380, PomBase:mah] synonym: "increased telomere anchoring at nuclear periphery during mitosis" EXACT [PomBase:vw] synonym: "increased telomere tethering at nuclear periphery during mitosis during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased telomere tethering at nuclear periphery during mitosis during vegetative growth" EXACT [PomBase:mah] synonym: "increased telomere tethering at nuclear periphery during mitotic M phase" RELATED [PomBase:mah] synonym: "increased telomere tethering at nuclear periphery during mitotic nuclear division" EXACT [GO:0140014] is_a: FYPO:0001515 ! abnormal telomere tethering at nuclear periphery during vegetative growth is_a: FYPO:0007769 ! increased heterochromatin tethering at nuclear periphery during mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T13:10:11Z" xsd:dateTime [Term] id: FYPO:0007771 name: abnormally clustered protein localization to nuclear envelope def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein is abnormally localized to one or more large clusters in the nuclear envelope. The protein may normally be distributed evenly in the nuclear envelope." [PMID:32109380, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localization to nuclear envelope, with protein in large clusters" EXACT [PomBase:mah] synonym: "abnormally clustered protein localisation to nuclear envelope" EXACT [PomBase:mah] synonym: "abnormally clustered protein localization to nuclear envelope during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormally clustered protein localization to nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "abnormally clustered protein localization to nuclear membrane" RELATED [PomBase:mah] is_a: FYPO:0004885 ! abnormal protein localization to nuclear envelope during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T13:25:16Z" xsd:dateTime [Term] id: FYPO:0007772 name: delayed onset of mitotic nuclear membrane reassembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which reformation of the nuclear envelope after mitotic nuclear division begins later than normal." [PMID:32109380, PomBase:mah] synonym: "delayed mitotic nuclear membrane reassembly" EXACT [PomBase:mah] synonym: "delayed onset of mitotic nuclear envelope reassembly" RELATED [GO:0007084] synonym: "delayed onset of mitotic nuclear membrane reassembly during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of mitotic nuclear membrane reassembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000815 ! abnormal nuclear envelope organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T13:28:22Z" xsd:dateTime [Term] id: FYPO:0007773 name: abnormal hyphal growth def: "A phenotype in which any aspect of hyphal growth is abnormal." [GO:0030448, PomBase:mah] is_a: FYPO:0000002 ! cell phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T13:50:17Z" xsd:dateTime [Term] id: FYPO:0007774 name: increased invasive hyphal growth def: "A phenotype in which fission yeast forms hyphae that invade the growth medium to a greater extent than normal. Invasively growing cells are wash-resistant when cultured in agar solid medium for several days." [PMID:31150379, PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:02:27Z" xsd:dateTime [Term] id: FYPO:0007775 name: increased hyphal length def: "A phenotype in which hyphae are longer than normal." [PMID:31150379, PomBase:mah] synonym: "long hyphae" EXACT [PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:03:58Z" xsd:dateTime [Term] id: FYPO:0007776 name: decreased hyphal length def: "A phenotype in which hyphae are shorter than normal." [PMID:31150379, PomBase:mah] synonym: "short hyphae" EXACT [PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:04:50Z" xsd:dateTime [Term] id: FYPO:0007777 name: increased hyphal branching def: "A phenotype in which hyphae form more branched filaments than normal." [PMID:31150379, PomBase:mah] synonym: "increased number of branched filaments" EXACT [PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:06:50Z" xsd:dateTime [Term] id: FYPO:0007778 name: decreased hyphal branching def: "A phenotype in which hyphae form fewer branched filaments than normal." [PMID:31150379, PomBase:mah] synonym: "decreased number of branched filaments" EXACT [PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:07:30Z" xsd:dateTime [Term] id: FYPO:0007779 name: increased mycelial expansion def: "A phenotype in which the mycelium formed by fission yeast undergoing hyphal growth covers a larger area than normal." [PMID:31150379, PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:25:05Z" xsd:dateTime [Term] id: FYPO:0007780 name: decreased mycelial expansion def: "A phenotype in which the mycelium formed by fission yeast undergoing hyphal growth covers a smaller area than normal." [PMID:31150379, PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:25:44Z" xsd:dateTime [Term] id: FYPO:0007781 name: delayed onset of hyphal transition def: "A phenotype in which the transition from yeast-form to hyphal growth begins later than normal." [PomBase:mah] synonym: "delayed hyphal transition" EXACT [PomBase:mah] synonym: "delayed onset of transition to hyphal growth" EXACT [PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:26:41Z" xsd:dateTime [Term] id: FYPO:0007782 name: abolished hyphal transition def: "A phenotype in which the transition from yeast-form to hyphal growth does not occur under conditions that normally induce it." [PomBase:mah] synonym: "abolished transition to hyphal growth" EXACT [PomBase:mah] synonym: "hyphal transition abolished" EXACT [PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:27:36Z" xsd:dateTime [Term] id: FYPO:0007783 name: abolished geometry scaling def: "A cell phenotype in which cellular geometry scaling, by which cells normally maintain a fairly constant length:diameter (width) ratio upon changes in cell volume, does not occur." [PMID:30664646, PomBase:mah] synonym: "abolished cell geometry scaling" EXACT [PomBase:mah] synonym: "abolished cellular geometry scaling" EXACT [PomBase:mah] synonym: "abolished geometry scaling during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished geometry scaling during vegetative growth" EXACT [PomBase:mah] synonym: "geometry scaling abolished" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: has_output FYPO:0001118 ! abnormal vegetative cell morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T14:45:48Z" xsd:dateTime [Term] id: FYPO:0007784 name: decreased protein localization to protein aggregate center def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to protein aggregate centers is decreased. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773, PMID:33946513, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to protein aggregate centre" EXACT [PomBase:mah] synonym: "decreased protein localization to PAC" EXACT [PomBase:mah] synonym: "decreased protein localization to PACs" EXACT [PomBase:vw] synonym: "decreased protein localization to protein aggregate center during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to protein aggregate center during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to protein aggregate center" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T10:57:52Z" xsd:dateTime [Term] id: FYPO:0007785 name: abnormal cell cycle arrest at meiotic G2/MI transition def: "A cellular process phenotype in which progression through the meiotic cell cycle is arrested at the G2/MI phase transition. Cells arrested at the G2/MI transition down-even in the presence of nutrients, in contrast with arrest at the mitotic G2/M transition, where cells continue to grow." [PMID:28476936, PomBase:jh, PomBase:mah] synonym: "abnormal cell cycle arrest at G2/M1 transition" EXACT [PomBase:vw] synonym: "abnormal cell cycle arrest at G2/MI transition of meiotic cell cycle" EXACT [GO:0008315] synonym: "abnormal cell cycle arrest at meiotic cell cycle G2/MI phase transition" EXACT [GO:0008315] synonym: "abnormal cell cycle arrest at meiotic G2/MI phase transition" EXACT [GO:0008315] synonym: "abnormal meiotic cell cycle arrest at G2/MI phase transition" EXACT [PomBase:mah] synonym: "abnormal meiotic cell cycle arrest at G2/MI transition" EXACT [PomBase:mah] synonym: "abolished growth during meiotic cell cycle arrest at G2/M1" RELATED [PomBase:vw] is_a: FYPO:0002224 ! abnormally arrested meiotic cell cycle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T12:12:49Z" xsd:dateTime [Term] id: FYPO:0007786 name: elongated cell with cell cycle arrest at meiotic G2/MI transition def: "A cell phenotype in which the cell is longer than normal, and progression through the meiotic cell cycle is arrested at the G2/MI phase transition. A cell can elongate when arrested at the G2/MI transition if it overcomes the growth arrest that usually occurs." [PMID:28476936, PomBase:jh, PomBase:mah] synonym: "elongated cell with abnormal cell cycle arrest at G2/M1 transition" EXACT [PomBase:vw] synonym: "elongated cell with abnormal cell cycle arrest at G2/MI transition of meiotic cell cycle" EXACT [GO:0008315] synonym: "elongated cell with abnormal cell cycle arrest at meiotic cell cycle G2/MI phase transition" EXACT [GO:0008315] synonym: "elongated cell with abnormal cell cycle arrest at meiotic G2/MI phase transition" EXACT [GO:0008315] synonym: "elongated cell with abnormal cell cycle arrest at meiotic G2/MI transition" EXACT [GO:0008315] synonym: "elongated cell with abnormal meiotic cell cycle arrest at G2/MI phase transition" EXACT [PomBase:mah] synonym: "elongated cell with abnormal meiotic cell cycle arrest at G2/MI transition" EXACT [PomBase:mah] synonym: "elongated cells during meiotic G2/M1 arrest" EXACT [PomBase:vw] synonym: "elongated cells during meiotic G2/MI arrest" EXACT [PomBase:vw] synonym: "long cell with cell cycle arrest at meiotic G2/MI transition" EXACT [PomBase:mah] is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0007785 ! abnormal cell cycle arrest at meiotic G2/MI transition property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T12:15:38Z" xsd:dateTime [Term] id: FYPO:0007787 name: increased transcription during cell cycle arrest at meiotic G2/MI transition def: "A cellular process phenotype in which transcription occurs to a greater extent than normal when the meiotic cell cycle is arrested at the G2/MI phase transition. All genes, or a specific subset of genes, may be affected." [PMID:28476936, PomBase:jh, PomBase:mah] synonym: "increased transcription during abnormal cell cycle arrest at G2/M1 transition" EXACT [PomBase:vw] synonym: "increased transcription during abnormal cell cycle arrest at G2/MI transition of meiotic cell cycle" EXACT [GO:0008315] synonym: "increased transcription during abnormal cell cycle arrest at meiotic cell cycle G2/MI phase transition" EXACT [GO:0008315] synonym: "increased transcription during abnormal cell cycle arrest at meiotic G2/MI phase transition" EXACT [GO:0008315] synonym: "increased transcription during abnormal cell cycle arrest at meiotic G2/MI transition" EXACT [GO:0008315] synonym: "increased transcription during abnormal meiotic cell cycle arrest at G2/MI phase transition" EXACT [PomBase:mah] synonym: "increased transcription during abnormal meiotic cell cycle arrest at G2/MI transition" EXACT [PomBase:mah] is_a: FYPO:0002875 ! increased transcription property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T12:25:45Z" xsd:dateTime [Term] id: FYPO:0007788 name: increased macroautophagy during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of macroautophagy is increased." [PMID:17121544, PomBase:mah] synonym: "increased macroautophagy during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000384 ! increased macroautophagy property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T12:51:49Z" xsd:dateTime [Term] id: FYPO:0007789 name: abolished hyphal growth def: "A phenotype in which hyphal growth does not occur." [PMID:31150379, PomBase:mah] is_a: FYPO:0007773 ! abnormal hyphal growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T13:22:53Z" xsd:dateTime [Term] id: FYPO:0007790 name: normal hyphal growth def: "A phenotype in which hyphal growth is normal (i.e. indistinguishable from wild type)." [PMID:31150379, PomBase:mah] synonym: "hyphal growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0000300 ! biological process phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T13:22:53Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-06-07T13:24:03Z" xsd:dateTime [Term] id: FYPO:0007791 name: RNA absent from cell during cellular response to magnesium starvation def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to magnesium starvation is lower than normal. Total RNA or a specific RNA may be affected." [PMID:33970532, PomBase:mah] synonym: "RNA absent from cell during cellular response to magnesium starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA absent from cell during cellular response to magnesium starvation during vegetative growth" EXACT [PomBase:mah] synonym: "RNA absent from cell during magnesium depletion" EXACT [PomBase:mah] synonym: "RNA absent from cell during magnesium deprivation" EXACT [PomBase:mah] synonym: "RNA absent from cell during magnesium starvation" EXACT [PomBase:mah] synonym: "transcripts absent from cell during cellular response to magnesium starvation" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to magnesium starvation" EXACT [PomBase:mah] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T13:54:34Z" xsd:dateTime [Term] id: FYPO:0007792 name: loss of viability upon magnesium starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to magnesium starvation." [PMID:33970532, PomBase:mah] synonym: "decreased viability upon magnesium starvation" EXACT [PomBase:mah] synonym: "loss of cell population viability upon magnesium starvation" EXACT [PomBase:mah] synonym: "loss of viability upon magnesium depletion" EXACT [PomBase:al] synonym: "loss of viability upon magnesium deprivation" EXACT [PomBase:mah] synonym: "loss of viability upon magnesium limitation" EXACT [PomBase:mah] synonym: "reduced viability upon magnesium starvation" EXACT [PomBase:mah] is_a: FYPO:0000244 ! loss of viability upon nutrient depletion property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T13:56:03Z" xsd:dateTime [Term] id: FYPO:0007793 name: delayed onset of increase in RNA level during cellular response to oxidative stress def: "A cell phenotype in which an increase in RNA level that occurs as part of a cellular response to oxidative stress begins later than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:10428959, PomBase:mah] synonym: "delayed increase in RNA level during cellular response to oxidative stress" EXACT [PomBase:mah] synonym: "delayed onset of increase in RNA level during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of increase in RNA level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "delayed onset of increase in RNA level in response to oxidative stress" EXACT [PomBase:mah] synonym: "delayed onset of increase in transcript level during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0001340 ! abnormal cellular response to oxidative stress during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T14:03:37Z" xsd:dateTime [Term] id: FYPO:0007794 name: RNA absent from cell during cellular response to oxidative stress def: "A cell phenotype in which the amount of RNA measured in a cell during a cellular response to oxidative stress is lower than normal. Total RNA or a specific RNA may be affected." [PMID:10428959, PomBase:mah] synonym: "RNA absent from cell during cellular response to oxidative stress during mitotic cell cycle" RELATED [PomBase:mah] synonym: "RNA absent from cell during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "transcripts absent from cell during cellular response to oxidative stress" EXACT [PomBase:vw] synonym: "undetectable RNA level during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T14:06:03Z" xsd:dateTime [Term] id: FYPO:0007795 name: two cell divisions prior to cell cycle arrest in mitotic G1 phase without nutrient starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G1 phase after the cells have undergone two rounds of cell division under nutrient-replete conditions. This arrest resembles that of wild-type cells under conditions of nitrogen starvation." [PMID:17121544, PMID:28476936, PomBase:mah] synonym: "two cell divisions prior to mitotic cell cycle arrest in G1 phase without nutrient starvation" EXACT [PomBase:mah] synonym: "two cell divisions prior to mitotic G1 arrest without nutrient starvation" EXACT [PomBase:mah] is_a: FYPO:0005097 ! abnormal cell cycle arrest in mitotic G1 phase property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T14:21:32Z" xsd:dateTime [Term] id: FYPO:0007796 name: abnormal glucan 1,3-alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of glucan 1,3-alpha-glucosidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T14:23:00Z" xsd:dateTime [Term] id: FYPO:0007797 name: decreased glucan 1,3-alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of glucan 1,3-alpha-glucosidase activity is decreased." [PomBase:mah] synonym: "reduced glucan 1,3-alpha-glucosidase activity" EXACT [PomBase:mah] is_a: FYPO:0007796 ! abnormal glucan 1,3-alpha-glucosidase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T14:23:53Z" xsd:dateTime [Term] id: FYPO:0007798 name: increased actin filament binding def: "A molecular function phenotype in which the binding of a protein to one or more actin filaments occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene." [PomBase:mah] synonym: "increased F-actin binding" EXACT [PomBase:mah] synonym: "increased filamentous actin binding" RELATED [PomBase:mah] synonym: "increased protein-protein interaction with actin filament" EXACT [PomBase:mah] is_a: FYPO:0001571 ! increased protein-protein interaction property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-09T14:25:05Z" xsd:dateTime [Term] id: FYPO:0007799 name: protein mislocalized to cell surface during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the cell surface is observed there." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "ectopic protein localization to cell surface during vegetative growth" EXACT [PomBase:vw] synonym: "protein mislocalised to cell surface during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cell surface during mitotic cell cycle" RELATED [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-14T14:05:53Z" xsd:dateTime [Term] id: FYPO:0007800 name: abolished protein localization to endoplasmic reticulum, with protein mislocalized to cell surface def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and some of the protein is present at the cell surface instead." [PMID:33536395, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished luminal ER protein retention" EXACT [PMID:33536395, PomBase:vw] synonym: "abolished protein localization to endoplasmic reticulum, with protein mislocalized to cell surface during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to endoplasmic reticulum, with protein mislocalized to cell surface during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to ER, with protein mislocalized to cell surface" EXACT [PomBase:mah] is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth is_a: FYPO:0007799 ! protein mislocalized to cell surface during vegetative growth is_a: FYPO:0008405 ! abolished protein localization to endoplasmic reticulum property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-14T14:07:35Z" xsd:dateTime [Term] id: FYPO:0007801 name: mislocalized hyphal septum def: "A physical cellular phenotype in which a dividing cell at the growith end of a hypha has a septum in an abnormal location. Normally, the septum forms in the cytosol-enriched portion of the cell, displaced slightly off-center toward the portion of the cell occupied by the vacuole." [PMID:30726171, PomBase:mah] synonym: "abnormal hyphal septum localization" RELATED [PomBase:mah] synonym: "abnormal hyphal septum location" EXACT [PomBase:mah] synonym: "abnormal hyphal septum position" EXACT [PomBase:mah] synonym: "abnormal hyphal septum positioning" RELATED [PomBase:mah] synonym: "mislocalised hyphal septum" EXACT [PomBase:mah] synonym: "mislocalized septum during hyphal growth" EXACT [PMID:30726171] synonym: "mislocalized septum in hypha" EXACT [PomBase:mah] synonym: "mislocalized septum in hyphal growth" EXACT [PMID:30726171] synonym: "misplaced hyphal septum" EXACT [PomBase:vw] is_a: FYPO:0004293 ! mislocalized septum property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-14T14:23:43Z" xsd:dateTime [Term] id: FYPO:0007802 name: short linear element def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form linear element that are shorter than normal." [PMID:33825974, PomBase:mah] synonym: "decreased linear element length" EXACT [PomBase:mah] synonym: "reduced linear element length" EXACT [PomBase:mah] is_a: FYPO:0004585 ! abnormal linear element morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-14T14:25:26Z" xsd:dateTime [Term] id: FYPO:0007803 name: abolished macroautophagy during leucine starvation def: "A cellular process phenotype in which macroautophagy does not occur when the cell is subject to leucine starvation." [GO:0016236, PMID:33534698, PomBase:mah] synonym: "abolished macroautophagy during cellular response to leucine starvation" EXACT [PomBase:mah] synonym: "abolished macroautophagy during leucine depletion" EXACT [PomBase:mah] synonym: "abolished macroautophagy during leucine deprivation" EXACT [PomBase:mah] synonym: "macroautophagy abolished during leucine starvation" EXACT [PomBase:mah] is_a: FYPO:0000380 ! abolished macroautophagy is_a: FYPO:0000860 ! abnormal metabolic process property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-14T14:28:52Z" xsd:dateTime [Term] id: FYPO:0007804 name: abnormal H3-H4 dimer loading onto DNA def: "A molecular function phenotype in which the ATP hydrolysis-dependent activity that loads H3-H4 histone dimers onto DNA is abnormal." [PMID:31848341, PomBase:mah] synonym: "abnormal H3-H4 dimer loading activity" EXACT [PomBase:mah] synonym: "abnormal histone H3-H4 dimer loading activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T13:01:30Z" xsd:dateTime [Term] id: FYPO:0007805 name: abolished H3-H4 dimer loading onto DNA def: "A molecular function phenotype in which the ATP hydrolysis-dependent activity that loads H3-H4 histone dimers onto DNA is absent." [PMID:31848341, PomBase:mah] synonym: "abolished H3-H4 dimer loading activity" EXACT [PomBase:mah] synonym: "abolished histone H3-H4 dimer loading activity" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0007804 ! abnormal H3-H4 dimer loading onto DNA property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T13:01:30Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T13:04:22Z" xsd:dateTime [Term] id: FYPO:0007806 name: normal endodeoxyribonuclease activator activity def: "A molecular function phenotype in which the activity of a endodeoxyribonuclease activator is normal (i.e. indistinguishable from wild type)." [GO:0140656, PMID:33836577, PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T13:31:38Z" xsd:dateTime [Term] id: FYPO:0007807 name: decreased endodeoxyribonuclease activator activity def: "A molecular function phenotype in which the activity of a endodeoxyribonuclease activator is decreased." [GO:0140656, PMID:33836577, PomBase:mah] is_a: FYPO:0007690 ! catalytic activity regulator phenotype property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T13:31:38Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T13:33:35Z" xsd:dateTime [Term] id: FYPO:0007808 name: resistance to valproic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of valproic acid than normal." [PomBase:mah] synonym: "resistance to valproic acid during mitotic cell cycle" RELATED [PomBase:mah] synonym: "resistance to valproic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T14:00:30Z" xsd:dateTime [Term] id: FYPO:0007809 name: normal cytoplasmic microtubules def: "A physical cellular phenotype in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cytoplasmic microtubule morphology" EXACT [PomBase:al] synonym: "normal cytoplasmic microtubule structure" NARROW [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular component property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-29T12:54:40Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007810 name: normal cytoplasmic microtubules during cellular response to pheromone def: "A physical cellular phenotype in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type) during a cellular response to a pheromone." [PMID:11950884, PomBase:mah] synonym: "normal cytoplasmic microtubule morphology during cellular response to pheromone" EXACT [PomBase:mah] synonym: "normal cytoplasmic microtubule structure during cellular response to pheromone" NARROW [PomBase:mah] synonym: "normal cytoplasmic microtubules during mating projection formation" RELATED [PomBase:vw] synonym: "normal cytoplasmic microtubules during response to pheromone" EXACT [PomBase:mah] synonym: "normal microtubules during cellular response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0007809 ! normal cytoplasmic microtubules property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-29T12:58:42Z" xsd:dateTime [Term] id: FYPO:0007811 name: decreased CMG replicative helicase activity def: "A molecular function phenotype in which the observed rate of CMG replicative helicase activity, the 3'-5' DNA helicase activity that unwinds DNA during nuclear DNA replication, is decreased." [PMID:34108240, PomBase:mah] synonym: "decreased 3'-5' DNA helicase activity during DNA replication" EXACT [PomBase:mah] synonym: "decreased Cdc45-MCM-GINS helicase activity" EXACT [PomBase:mah] synonym: "decreased Cdc45-MCM-GINS replicative helicase activity" EXACT [PomBase:mah] synonym: "decreased replicative helicase activity" EXACT [PomBase:mah] is_a: FYPO:0002100 ! abnormal 3'-5' DNA helicase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-29T13:24:16Z" xsd:dateTime [Term] id: FYPO:0007812 name: sensitive to stavudine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to stavudine. Cells stop growing (and may die) at a concentration of stavudine that allows wild type cells to grow." [PMID:34108240, PomBase:mah] synonym: "hypersensitive to stavudine" EXACT [PomBase:mah] synonym: "sensitive to stavudine during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sensitive to stavudine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-29T13:25:57Z" xsd:dateTime [Term] id: FYPO:0007813 name: normal growth on stavudine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing stavudine." [PMID:34108240, PomBase:mah] synonym: "normal cell population growth in presence of stavudine" EXACT [PomBase:mah] synonym: "normal cell population growth on stavudine" EXACT [PomBase:al, PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on stavudine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-29T13:26:55Z" xsd:dateTime [Term] id: FYPO:0007814 name: increased rate of mitotic DNA replication elongation during cellular response to hydroxyurea def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is increased during a cellular response to hydroxyurea." [PMID:34108240, PomBase:mah] synonym: "increased rate of DNA replication elongation during cellular response to hydroxyurea during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased rate of DNA strand elongation involved in mitotic DNA replication during cellular response to hydroxyurea" EXACT [PomBase:mah] synonym: "increased rate of DNA strand elongation involved in nuclear cell cycle DNA replication during cellular response to hydroxyurea" EXACT [GO:1902319] synonym: "increased rate of mitotic DNA replication elongation during cellular response to HU" EXACT [PomBase:mah] synonym: "increased rate of mitotic DNA replication elongation during cellular response to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006730 ! abnormal mitotic DNA replication elongation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-06-29T13:28:16Z" xsd:dateTime [Term] id: FYPO:0007815 name: normal protein localization to protein aggregate center def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to protein aggregate centers is normal (i.e. indistinguishable from wild type). Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:33386485, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to protein aggregate centre" EXACT [PomBase:mah] synonym: "normal protein localization to PAC" EXACT [PomBase:mah] synonym: "normal protein localization to PACs" EXACT [PomBase:vw] synonym: "normal protein localization to protein aggregate center during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein localization to protein aggregate center during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-06T13:20:31Z" xsd:dateTime [Term] id: FYPO:0007816 name: increased cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in a cell (total or free) is higher than normal." [PMID:34147496, PomBase:mah] synonym: "increased cellular polyphosphate level during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased cellular polyphosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased polyphosphate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-06T13:49:46Z" xsd:dateTime [Term] id: FYPO:0007817 name: mislocalized nucleus during G0 def: "A physical cellular phenotype in which a cell has a nucleus in an abnormal location during G0 phase. The normal location is at the midpoint of the long axis of the cell." [PMID:34147496, PomBase:mah] synonym: "abnormal nucleus location during G0" EXACT [PomBase:mah] synonym: "abnormal nucleus position during G0" EXACT [PomBase:mah] synonym: "displaced nucleus during G0" EXACT [PomBase:vw] synonym: "mislocalised nucleus during G0" EXACT [PomBase:mah] synonym: "mislocalized nucleus during cell quiescence" EXACT [PomBase:mah] synonym: "mislocalized nucleus during quiescence" EXACT [PomBase:mah] synonym: "misplaced nuclei during G0" EXACT [PomBase:vw] synonym: "misplaced nucleus during G0" EXACT [PomBase:vw] synonym: "nuclear displacement during G0" EXACT [PomBase:vw] is_a: FYPO:0002069 ! mislocalized nucleus property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-06T13:51:07Z" xsd:dateTime [Term] id: FYPO:0007818 name: decreased protein ubiquitination during nitrogen starvation def: "A cellular process phenotype in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is decreased when the cell is subject to nitrogen starvation." [PMID:34147496, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein ubiquitination during nitrogen depletion" EXACT [PomBase:vw] synonym: "decreased protein ubiquitination during nitrogen deprivation" EXACT [PomBase:vw] synonym: "decreased protein ubiquitinylation during nitrogen starvation" EXACT [PomBase:mah] synonym: "decreased protein ubiquitylation during nitrogen starvation" EXACT [PomBase:mah] synonym: "reduced protein ubiquitination during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0007946 ! decreased protein ubiquitination property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-06T13:49:46Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-07-06T13:52:54Z" xsd:dateTime [Term] id: FYPO:0007820 name: polyphosphate absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in a cell is too low to detect." [PMID:34147496, PomBase:mah] synonym: "polyphosphate absent from cell during mitotic cell cycle" RELATED [PomBase:mah] synonym: "polyphosphate absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T14:28:08Z" xsd:dateTime [Term] id: FYPO:0007821 name: large vacuoles def: "A physical cellular phenotype in which vacuoles are larger than normal." [PomBase:mah] synonym: "enlarged vacuoles" EXACT [PomBase:mah] is_a: FYPO:0002257 ! abnormal vacuolar morphology property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:00:18Z" xsd:dateTime [Term] id: FYPO:0007822 name: large vacuoles during G0 def: "A physical cellular phenotype in which vacuoles are larger than normal in G0 phase." [PMID:34147496, PomBase:mah] synonym: "enlarged vacuoles during G0" EXACT [PomBase:mah] synonym: "large vacuoles during cell quiescence" EXACT [PomBase:mah] synonym: "large vacuoles during quiescence" EXACT [PomBase:mah] is_a: FYPO:0007821 ! large vacuoles property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:05:15Z" xsd:dateTime [Term] id: FYPO:0007823 name: abnormal quorum sensing def: "A biological process phenotype in which any aspect of quorum sensing is abnormal." [GO:0009372, PMID:31150379, PomBase:mah] is_a: FYPO:0005447 ! abnormal biological process property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:16:59Z" xsd:dateTime [Term] id: FYPO:0007824 name: decreased quorum sensing response def: "A biological process phenotype in which a response to quorum sensing molecules (QSMs) is decreased. The amount of QSMs may be normal." [PMID:31150379, PomBase:mah] synonym: "deficient in quorum sensing" EXACT [PMID:31150379, PomBase:mah] synonym: "quorum sensing attenuated" EXACT [PMID:31150379, PomBase:mah] synonym: "quorum sensing decreased" EXACT [PMID:31150379, PomBase:mah] synonym: "quorum sensing deficient" EXACT [PMID:31150379, PomBase:mah] is_a: FYPO:0007823 ! abnormal quorum sensing property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:18:26Z" xsd:dateTime [Term] id: FYPO:0007825 name: decreased protein level during cellular response to amino acid starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to amino acid starvation is lower than normal. Total protein or a specific protein may be affected." [PMID:33534698, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to amino acid starvation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to amino acid starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to amino acid starvation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to amino acid starvation" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:38:34Z" xsd:dateTime [Term] id: FYPO:0007826 name: decreased protein level during cellular response to leucine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to leucine starvation is lower than normal. Total protein or a specific protein may be affected." [PMID:33534698, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein accumulation during cellular response to leucine starvation" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to leucine starvation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to leucine starvation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to leucine starvation" EXACT [PomBase:mah] is_a: FYPO:0007825 ! decreased protein level during cellular response to amino acid starvation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:40:00Z" xsd:dateTime [Term] id: FYPO:0007827 name: normal actomyosin contractile ring organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring organization is normal (i.e. indistinguishable from wild type). The process results in the assembly, arrangement of constituent parts, or disassembly of the actomyosin contractile ring." [GO:0044837, PomBase:mah] synonym: "normal actomyosin contractile ring organisation" EXACT [PomBase:mah] synonym: "normal actomyosin contractile ring organization during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring organization during vegetative growth" EXACT [PomBase:mah] synonym: "normal contractile ring organization" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:41:21Z" xsd:dateTime [Term] id: FYPO:0007828 name: normal actomyosin contractile ring maturation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring maturation is normal (i.e. indistinguishable from wild type)." [GO:1902406, PMID:34133210, PomBase:mah] synonym: "normal actomyosin contractile ring maintenance" EXACT [GO:1902406] synonym: "normal actomyosin contractile ring maturation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal actomyosin contractile ring maturation during vegetative growth" EXACT [PomBase:mah] synonym: "normal contractile ring maturation" EXACT [PomBase:mah] synonym: "normal mitotic actomyosin contractile ring maintenance" EXACT [GO:1902406] is_a: FYPO:0007827 ! normal actomyosin contractile ring organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T15:55:51Z" xsd:dateTime [Term] id: FYPO:0007829 name: premature protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division begins earlier than normal." [PMID:34133210, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "advanced protein localization to cell division site" EXACT [PomBase:mah] synonym: "precocious protein localization to cell division site" EXACT [PATO:0000694] synonym: "premature protein localisation to cell division site" EXACT [PomBase:mah] synonym: "premature protein localization to cell division site during mitotic cell cycle" RELATED [PomBase:mah] synonym: "premature protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] synonym: "premature protein recruitment to cell division site" RELATED [PomBase:vw] is_a: FYPO:0001401 ! abnormal protein localization to cell division site property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-13T16:03:31Z" xsd:dateTime [Term] id: FYPO:0007830 name: narrow protein radial density distribution in medial cortical node during mitotic interphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein located in the medial cortical nodes occupies an area with a smaller radius than normal during interphase of the mitotic cell cycle. The nodes are \"precursor\" nodes that exist before the contractile ring is formed." [PMID:33496728, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein radial density distribution in medial cortical node during mitotic interphase" EXACT [PomBase:mah] synonym: "decreased protein RDD in medial cortical node during mitotic interphase" EXACT [PMID:33496728] synonym: "narrow protein radial density distribution in medial cortical node during interphase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "narrow protein radial density distribution in medial cortical node during mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "narrow protein radial density distribution in medial cortical P-node" RELATED [PMID:33496728] synonym: "narrow protein radial density distribution in medial cortical precursor node" RELATED [PMID:33496728] synonym: "narrow protein RDD in medial cortical node during mitotic interphase" EXACT [PMID:33496728] synonym: "narrow radial density distribution of protein in medial cortical node during mitotic interphase" EXACT [PomBase:mah] synonym: "reduced protein radial density distribution in medial cortical node during mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:33:25Z" xsd:dateTime [Term] id: FYPO:0007831 name: narrow protein radial density distribution in medial cortical node during mitotic anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein located in the medial cortical nodes occupies an area with a smaller radius than normal during anaphase B of mitosis. The nodes are \"ring\" nodes, observed when the contractile ring is constricting." [PMID:33496728, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein radial density distribution in medial cortical node during mitotic anaphase B" EXACT [PomBase:mah] synonym: "decreased protein RDD in medial cortical node during mitotic anaphase B" EXACT [PMID:33496728] synonym: "narrow protein radial density distribution in medial cortical node during anaphase B" EXACT [PomBase:mah] synonym: "narrow protein radial density distribution in medial cortical node during mitotic anaphase B during vegetative growth" EXACT [PomBase:mah] synonym: "narrow protein radial density distribution in medial cortical R-node" RELATED [PMID:33496728] synonym: "narrow protein radial density distribution in medial cortical ring node" RELATED [PMID:33496728] synonym: "narrow protein RDD in medial cortical node during mitotic anaphase B" EXACT [PMID:33496728] synonym: "narrow radial density distribution of protein in medial cortical node during mitotic anaphase B" EXACT [PomBase:mah] synonym: "reduced protein radial density distribution in medial cortical node during mitotic anaphase B" EXACT [PomBase:mah] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:35:02Z" xsd:dateTime [Term] id: FYPO:0007832 name: delayed onset of protein localization to medial cortical node def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes begins later than normal." [PMID:33496728, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "delayed onset of protein localisation to medial cortical node" EXACT [PomBase:mah] synonym: "delayed onset of protein localization to cortical medial dot" EXACT [PomBase:vw] synonym: "delayed onset of protein localization to cytokinetic nodes" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to medial cortical node during mitotic cell cycle" RELATED [PomBase:mah] synonym: "delayed onset of protein localization to medial cortical node during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein localization to medial cortical node" EXACT [PomBase:mah] is_a: FYPO:0003289 ! abnormal protein localization to medial cortical node property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:35:56Z" xsd:dateTime [Term] id: FYPO:0007833 name: abnormal nucleosome positioning at protein-coding gene def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal in regions containing protein-coding genes." [PMID:31837996, PomBase:mah] synonym: "abnormal genic nucleosome positioning" RELATED [PomBase:mah] synonym: "abnormal nucleosome positioning at protein coding gene" EXACT [PomBase:mah] synonym: "abnormal nucleosome positioning at protein-coding gene during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal nucleosome positioning at protein-coding gene during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome positioning over gene body" RELATED [PomBase:mah] synonym: "abnormal nucleosome spacing at protein-coding gene" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000854 ! abnormal nucleosome positioning in euchromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:53:23Z" xsd:dateTime [Term] id: FYPO:0007834 name: protein displaced from 5' end to 3' end of RNA polymerase II-transcribed genes def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is altered such that more of the protein is present at the 3' end, and less at the 5' end, than normal." [PMID:31837996, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localization to chromatin at 5' end of RNA polymerase II-transcribed genes with increased localization towards 3' end" EXACT [PomBase:vw] synonym: "protein displaced from 5' end to 3' end of RNA polymerase II-transcribed genes during mitotic cell cycle" RELATED [PomBase:mah] synonym: "protein displaced from 5' end to 3' end of RNA polymerase II-transcribed genes during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0006020 ! abnormal protein distribution along RNA polymerase II-transcribed genes property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:55:38Z" xsd:dateTime [Term] id: FYPO:0007835 name: increased histone binding def: "A molecular function phenotype in which histone binding by a gene product (usually a protein) in a mutant occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene." [PMID:31837996, PomBase:mah] synonym: "increased protein-histone interaction" EXACT [PomBase:mah] is_a: FYPO:0007157 ! abnormal histone binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:57:04Z" xsd:dateTime [Term] id: FYPO:0007836 name: increased nucleosome occupancy at subtelomere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at subtelomeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:31837996, PomBase:mah] synonym: "increased nucleosome occupancy at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased nucleosome occupancy at subtelomere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000855 ! abnormal nucleosome positioning in heterochromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:58:45Z" xsd:dateTime [Term] id: FYPO:0007837 name: decreased nucleosome occupancy at subtelomere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at subtelomeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:31837996, PomBase:mah] synonym: "decreased nucleosome occupancy at subtelomere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased nucleosome occupancy at subtelomere during vegetative growth" EXACT [PomBase:mah] synonym: "reduced nucleosome occupancy at subtelomere" EXACT [PomBase:mah] is_a: FYPO:0000855 ! abnormal nucleosome positioning in heterochromatin property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-07-21T14:59:20Z" xsd:dateTime [Term] id: FYPO:0007838 name: normal peptide alpha-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is normal (i.e. indistinguishable from wild type)." [PMID:34019809, PomBase:mah] synonym: "normal NAT activity" RELATED [GO:0004596] synonym: "normal protein N-terminal acetyltransferase activity" EXACT [GO:0004596] is_a: FYPO:0000660 ! normal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-09T12:52:15Z" xsd:dateTime [Term] id: FYPO:0007839 name: abnormal peptide alpha-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is abnormal." [PMID:34019809, PomBase:mah] synonym: "abnormal NAT activity" RELATED [GO:0004596] synonym: "abnormal protein N-terminal acetyltransferase activity" EXACT [GO:0004596] is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-09T12:53:14Z" xsd:dateTime [Term] id: FYPO:0007840 name: increased peptide alpha-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is increased." [PMID:34019809, PomBase:mah] synonym: "increased NAT activity" RELATED [GO:0004596] synonym: "increased protein N-terminal acetyltransferase activity" EXACT [GO:0004596] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0007839 ! abnormal peptide alpha-N-acetyltransferase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-09T12:54:43Z" xsd:dateTime [Term] id: FYPO:0007841 name: decreased peptide alpha-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is decreased." [PMID:34019809, PomBase:mah] synonym: "decreased NAT activity" RELATED [GO:0004596] synonym: "decreased protein N-terminal acetyltransferase activity" EXACT [GO:0004596] synonym: "reduced peptide alpha-N-acetyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0007839 ! abnormal peptide alpha-N-acetyltransferase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-09T12:55:34Z" xsd:dateTime [Term] id: FYPO:0007842 name: abolished peptide alpha-N-acetyltransferase activity def: "A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is absent." [PMID:34019809, PomBase:mah] synonym: "abolished NAT activity" RELATED [GO:0004596] synonym: "abolished protein N-terminal acetyltransferase activity" EXACT [GO:0004596] synonym: "peptide alpha-N-acetyltransferase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0007839 ! abnormal peptide alpha-N-acetyltransferase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-09T12:56:08Z" xsd:dateTime [Term] id: FYPO:0007843 name: normal nucleosome positioning at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in centromeric regions is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PMID:17363370, PomBase:mah] synonym: "normal nucleosome occupancy at centromere" RELATED [PomBase:mah, PomBase:vw] synonym: "normal nucleosome occupancy at centromeric chromatin" RELATED [PomBase:mah, PomBase:vw] synonym: "normal nucleosome positioning at centromeric chromatin" EXACT [PomBase:mah, PomBase:vw] is_a: FYPO:0000856 ! normal nucleosome positioning property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-16T14:26:35Z" xsd:dateTime [Term] id: FYPO:0007844 name: increased histone H3-K9 monomethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the monomethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PMID:17363370, PomBase:mah] synonym: "increased centromeric histone H3-K9 monomethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3 K9 monomethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 monomethylation at centromere during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased histone H3K9 monomethylation at centromere during vegetative growth" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 monomethylation at centromere during vegetative growth" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0005066 ! increased histone H3-K9 methylation at centromere during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-16T14:31:09Z" xsd:dateTime created_by: midori [Term] id: FYPO:0007845 name: increased rate of RNA catabolic process during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of an RNA catabolic process is increased." [PomBase:mah] synonym: "decreased rate of RNA breakdown during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of RNA catabolic process during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased rate of RNA catabolism during vegetative growth" EXACT [GO:0006401] synonym: "decreased rate of RNA degradation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of RNA catabolic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002136 ! abnormal RNA catabolic process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T12:55:24Z" xsd:dateTime [Term] id: FYPO:0007846 name: short meiotic spindle during anaphase I def: "A physical cellular phenotype in which the spindle is shorter than normal during anaphase of meiosis I." [PMID:34346498, PomBase:mah] synonym: "short meiosis I spindle during anaphase" EXACT [PomBase:mah] synonym: "short spindle during anaphase of meiosis I" EXACT [PomBase:mah] synonym: "short spindle during meiotic anaphase I" EXACT [PomBase:mah] is_a: FYPO:0000735 ! short meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:28:09Z" xsd:dateTime [Term] id: FYPO:0007847 name: long meiosis I spindle def: "A physical cellular phenotype in which the meiotic spindle is longer than normal during meiosis I." [PMID:34346498, PomBase:mah] synonym: "elongated meiosis I spindle" EXACT [PomBase:mah] synonym: "long spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "long spindle during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0000736 ! long meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:29:54Z" xsd:dateTime [Term] id: FYPO:0007848 name: meiotic spindle self-assembly def: "A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during one or both meiotic nuclear divisions. This phenotype is observed in the absence of both bouquet formation and meiotic SPB insertion into the nuclear envelope." [PMID:34346498, PomBase:mah] comment: Consider also annotating to 'meiotic spindle pole body detached from nucleus' (FYPO:0006365). synonym: "acentrosomal meiotic spindle assembly" RELATED [PMID:34346498] synonym: "acentrosomal spindle assembly during meiosis" RELATED [PMID:34346498] synonym: "meiotic SPB-independent spindle" RELATED [PomBase:vw] synonym: "SPB-independent meiotic spindle assembly" EXACT [PomBase:mah] synonym: "SPB-independent spindle assembly during meiosis" EXACT [PomBase:mah] synonym: "spindle pole body-independent meiotic spindle assembly" EXACT [PomBase:mah] synonym: "spindle pole body-independent spindle assembly during meiosis" EXACT [PomBase:mah] synonym: "spindle self-assembly during meiosis" EXACT [PomBase:mah] synonym: "spindle self-assembly during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0000737 ! abnormal meiotic spindle assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:31:15Z" xsd:dateTime [Term] id: FYPO:0007849 name: spindle self-assembly during meiosis I def: "A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during the first meiotic nuclear division." [PMID:34346498, PomBase:mah] comment: Consider also annotating to 'meiotic spindle pole body detached from nucleus' (FYPO:0006365). synonym: "acentrosomal meiotic spindle assembly" RELATED [PMID:34346498] synonym: "acentrosomal spindle assembly during meiosis I" RELATED [PMID:34346498] synonym: "meiosis I spindle self-assembly" EXACT [PomBase:mah] synonym: "meiotic SPB-independent spindle in meiosis I" RELATED [PomBase:vw] synonym: "SPB-independent meiosis I spindle assembly" EXACT [PomBase:mah] synonym: "SPB-independent spindle assembly during meiosis I" EXACT [PomBase:mah] synonym: "spindle pole body-independent meiosis I spindle assembly" EXACT [PomBase:mah] synonym: "spindle pole body-independent spindle assembly during meiosis I" EXACT [PomBase:mah] synonym: "spindle self-assembly during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007745 ! abnormal spindle assembly during meiosis I is_a: FYPO:0007848 ! meiotic spindle self-assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:34:41Z" xsd:dateTime [Term] id: FYPO:0007850 name: spindle self-assembly during meiosis II def: "A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during the second meiotic nuclear division." [PMID:34346498, PomBase:mah] comment: Consider also annotating to 'meiotic spindle pole body detached from nucleus' (FYPO:0006365). synonym: "acentrosomal meiotic spindle assembly" RELATED [PMID:34346498] synonym: "acentrosomal spindle assembly during meiosis II" RELATED [PMID:34346498] synonym: "meiosis II spindle self-assembly" EXACT [PomBase:mah] synonym: "meiotic SPB-independent spindle in meiosis II" RELATED [PomBase:vw] synonym: "SPB-independent meiosis II spindle assembly" EXACT [PomBase:mah] synonym: "SPB-independent spindle assembly during meiosis II" EXACT [PomBase:mah] synonym: "spindle pole body-independent meiosis II spindle assembly" EXACT [PomBase:mah] synonym: "spindle pole body-independent spindle assembly during meiosis II" EXACT [PomBase:mah] synonym: "spindle self-assembly during second meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0004510 ! abnormal spindle assembly during meiosis II is_a: FYPO:0007848 ! meiotic spindle self-assembly property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:35:31Z" xsd:dateTime [Term] id: FYPO:0007851 name: abolished spindle assembly during meiosis I def: "A cell phenotype in which spindle assembly does not occur during the first meiotic nuclear division." [PMID:34346498, PomBase:mah] comment: Consider also annotating to 'meiotic spindle pole body detached from nucleus' (FYPO:0006365). synonym: "abolished meiosis I spindle assembly" EXACT [PomBase:vw] synonym: "abolished spindle assembly during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007745 ! abnormal spindle assembly during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:36:59Z" xsd:dateTime [Term] id: FYPO:0007852 name: normal meiotic spindle polarity def: "A physical cellular phenotype in which spindle microtubules are oriented normally, i.e. with minus ends at the spindle poles and plus ends at the midzone, during or both meiotic nuclear divisions." [PMID:34346498, PomBase:mah] comment: Consider also annotating to 'meiotic spindle pole body detached from nucleus' (FYPO:0006365). synonym: "normal meiotic spindle microtubule polarity" EXACT [PomBase:mah] synonym: "normal microtubule polarity in meiotic spindle" EXACT [PomBase:mah] is_a: FYPO:0004160 ! normal meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-21T13:38:49Z" xsd:dateTime [Term] id: FYPO:0007853 name: normal protein localization to centromere def: "A cell phenotype in which the localization of a protein to the centromere of a chromosome is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to centromere" EXACT [PomBase:mah] synonym: "normal protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "normal protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "normal protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0003627 ! normal protein localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T10:50:26Z" xsd:dateTime [Term] id: FYPO:0007854 name: normal protein localization to kinetochore during meiotic anaphase I def: "A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during anaphase of meiosis I." [PMID:11331883, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to kinetochore during meiotic anaphase I" EXACT [PomBase:mah] synonym: "normal protein localization to kinetochore during meiosis I anaphase" EXACT [PomBase:vw] is_a: FYPO:0004214 ! normal protein localization to kinetochore during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T11:20:33Z" xsd:dateTime [Term] id: FYPO:0007855 name: decreased protein phosphorylation during mitotic spindle assembly checkpoint signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitotic spindle assembly checkpoint signaling." [PMID:12606573, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased duration of protein localisation to spindle during meiosis I" EXACT [PomBase:mah] synonym: "increased duration of protein localization to meiosis I spindle" EXACT [PomBase:vw] synonym: "increased duration of protein localization to meiotic spindle during meiosis I" EXACT [PomBase:mah] synonym: "increased duration of protein localization to spindle during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "prolonged protein localization to spindle during meiosis I" EXACT [PomBase:mah] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T11:23:39Z" xsd:dateTime [Term] id: FYPO:0007856 name: increased duration of protein localization to spindle during meiosis I def: "A cell phenotype in which the duration of localization of a protein to the spindle is longer than normal during the first meiotic nuclear division." [PMID:12606573, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein phosphorylation during mitotic cell cycle spindle assembly checkpoint signaling" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic spindle assembly checkpoint signalling" EXACT [PomBase:mah] synonym: "decreased protein phosphorylation during mitotic spindle checkpoint" RELATED [PomBase:vw] synonym: "decreased protein phosphorylation during signal transduction involved in mitotic spindle assembly checkpoint" EXACT [GO:0072480] synonym: "decreased protein phosphorylation during spindle assembly checkpoint signaling during mitotic cell cycle" EXACT [PomBase:mah] synonym: "reduced protein phosphorylation during mitotic spindle assembly checkpoint signaling" EXACT [PomBase:mah] is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T11:26:16Z" xsd:dateTime [Term] id: FYPO:0007857 name: normal protein localization to meiotic spindle midzone during meiosis I def: "A cellular process phenotype in which the localization of a protein to the spindle midzone is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. The meiotic spindle midzone is the area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap." [GO:1903096, GO:1990385, PMID:34346498, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to meiotic spindle midzone during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to meiosis I spindle midzone" EXACT [PomBase:mah] synonym: "normal protein localization to spindle midzone during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007750 ! normal protein localization to meiotic spindle during meiosis I property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T12:33:03Z" xsd:dateTime [Term] id: FYPO:0007858 name: mitotic DNA re-replication in absence of mitotic spindle def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes one or more rounds of rereplication of the entire genome without forming a mitotic spindle or undergoing cytokinesis." [PMID:20967237, PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication in absence of mitotic spindle" EXACT [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication in absence of mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication in absence of mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic DNA re-replication in the absence of normal mitotic spindle assembly and cytokinesis" EXACT [PomBase:jh] is_a: FYPO:0001425 ! abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T12:55:47Z" xsd:dateTime [Term] id: FYPO:0007859 name: nuclear division in absence of mitotic spindle def: "A cellular process phenotype in which the nucleus divides into two or more fragments, each enclosed by nuclear envelope and containing a DNA mass, in a cell that does not form a mitotic spindle or undergo cytokinesis. In these cells, the nucleus does not elongate into a dumbbell shape, but instead the nuclear envelope takes on a ruffled aspect and then eventually pinches into two nuclear masses." [PMID:20967237, PomBase:jh, PomBase:mah] synonym: "nuclear division in absence of mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "nuclear division in absence of mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear fission" EXACT [PomBase:jh] synonym: "nuclear fission in absence of mitotic spindle" EXACT [PomBase:jh] synonym: "rel syn DNA segregation in absence of mitotic spindle" RELATED [PomBase:jh] is_a: FYPO:0000337 ! abnormal mitosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T13:00:00Z" xsd:dateTime [Term] id: FYPO:0007860 name: spindle pole body separation in absence of mitotic spindle def: "A cellular process phenotype in which the spindle pole body (SPB) duplicates normally, and the SPBs separate, in a cell that does not form a mitotic spindle or undergo cytokinesis. The DNA and nucleus may go on to divide in the absence of a spindle, with each DNA mass associated with an SPB." [PMID:20967237, PomBase:jh, PomBase:mah] synonym: "SPB separation in absence of mitotic spindle" EXACT [PomBase:mah] synonym: "spindle pole body separation in absence of mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "spindle pole body separation in absence of mitotic spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002734 ! abnormal cell cycle process relationship: part_of FYPO:0007859 ! nuclear division in absence of mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T13:02:38Z" xsd:dateTime [Term] id: FYPO:0007861 name: sister chromatid separation during nuclear fission def: "A cellular process phenotype in which sister chromatids become physically detached in a cell that does not form a mitotic spindle or undergo cytokinesis. The DNA and nucleus may go on to divide in the absence of a spindle, with sister chromatids segregated to separate DNA masses." [PMID:20967237, PomBase:jh, PomBase:mah] synonym: "chromosome separation during nuclear fission" EXACT [PomBase:jh] synonym: "sister chromatid separation during nuclear division in absence of mitotic spindle" EXACT [PomBase:mah] synonym: "sister chromatid separation during nuclear fission during mitotic cell cycle" RELATED [PomBase:mah] synonym: "sister chromatid separation during nuclear fission during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002734 ! abnormal cell cycle process relationship: part_of FYPO:0007859 ! nuclear division in absence of mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T13:06:32Z" xsd:dateTime [Term] id: FYPO:0007862 name: centromere clustering at nuclear periphery during nuclear division in absence of mitotic spindle def: "A cellular process phenotype in which centromeres and kinetochores remain associated with the spindle pole body during nuclear division in a that does not form a mitotic spindle or undergo cytokinesis." [PMID:20967237, PomBase:jh, PomBase:mah] synonym: "abnormal centromere-SPB association at mitosis" RELATED [PomBase:jh] synonym: "centromere clustering at nuclear periphery during nuclear division in absence of mitotic spindle during mitotic cell cycle" RELATED [PomBase:mah] synonym: "centromere clustering at nuclear periphery during nuclear division in absence of mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "centromere clustering at nuclear periphery during nuclear fission" EXACT [PomBase:mah] synonym: "chromosome SPB attachment during nuclear fission" EXACT [PomBase:jh] is_a: FYPO:0002734 ! abnormal cell cycle process relationship: part_of FYPO:0007859 ! nuclear division in absence of mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T13:11:27Z" xsd:dateTime [Term] id: FYPO:0007863 name: abnormal protein localization to spindle def: "A cell phenotype in which the localization of a protein to the mitotic or meiotic spindle is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. subset: qc_do_not_manually_annotate synonym: "abnormal protein localisation to spindle" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T14:06:54Z" xsd:dateTime [Term] id: FYPO:0007864 name: abolished protein localization to meiotic spindle pole during meiosis I def: "A cell phenotype in which the localization of a protein to one or both poles of the meiotic spindle does not occur during the first meiotic nuclear division." [PMID:34346498, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to meiotic spindle pole during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localisation to spindle pole during meiosis I" EXACT [PomBase:mah] synonym: "abolished protein localization to meiosis I spindle pole" EXACT [PomBase:mah] synonym: "abolished protein localization to spindle pole during first meiotic nuclear division" EXACT [PomBase:mah] synonym: "protein localization to meiotic spindle pole during meiosis I abolished" EXACT [PomBase:mah] is_a: FYPO:0001375 ! abolished protein localization is_a: FYPO:0006454 ! abnormal protein localization to meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T14:12:57Z" xsd:dateTime [Term] id: FYPO:0007865 name: normal protein localization to spindle def: "A cell phenotype in which the localization of a protein to the mitotic or meiotic spindle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. subset: qc_do_not_manually_annotate synonym: "normal protein localisation to spindle" EXACT [PomBase:mah] is_a: FYPO:0003627 ! normal protein localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T14:22:50Z" xsd:dateTime [Term] id: FYPO:0007866 name: normal protein localization to meiotic spindle def: "A cell phenotype in which the localization of a protein to the meiotic spindle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to meiotic spindle" EXACT [PomBase:mah] synonym: "normal protein localization to spindle during meiosis" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole during meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0003790 ! normal protein localization during meiosis is_a: FYPO:0007865 ! normal protein localization to spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T14:24:16Z" xsd:dateTime [Term] id: FYPO:0007867 name: normal protein localization to meiotic spindle pole during meiosis I def: "A cell phenotype in which the localization of a protein to one or both poles of the meiotic spindle is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division." [PMID:34346498, PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to meiotic spindle pole during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localisation to spindle pole during meiosis I" EXACT [PomBase:mah] synonym: "normal protein localization to meiosis I spindle pole" EXACT [PomBase:mah] synonym: "normal protein localization to spindle pole during first meiotic nuclear division" EXACT [PomBase:mah] is_a: FYPO:0007866 ! normal protein localization to meiotic spindle property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-09-28T14:26:00Z" xsd:dateTime [Term] id: FYPO:0007868 name: sensitive to actin polymerization inhibitor def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a substance that inhibits actin polymerization. Cells stop growing (and may die) at a concentration of an actin polymerization inhibitor that allows wild type cells to grow." [PomBase:mah] synonym: "sensitive to actin cytoskeleton damaging agent" RELATED [PomBase:vw] synonym: "sensitive to actin polymerisation inhibitor" EXACT [CHEBI:70728] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:20:06Z" xsd:dateTime [Term] id: FYPO:0007869 name: abnormal protein localization to lateral cell cortex def: "A cell phenotype in which the localization of a protein to the lateral cell cortex is abnormal." [PomBase:mah] synonym: "abnormal protein localisation to lateral cell cortex" EXACT [PomBase:mah] synonym: "abnormal protein localization to lateral cortex" EXACT [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:25:42Z" xsd:dateTime [Term] id: FYPO:0007870 name: abolished protein localization to lateral cell cortex, with protein mislocalized to cytoplasm, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the lateral cell cortex is abolished, and the protein is present in the cytoplasm instead." [PMID:34533984, PomBase:mah] synonym: "abolished protein localisation to lateral cell cortex, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein localization to cell side, with protein mislocalized to cytoplasm, during vegetative growth" RELATED [PomBase:vw] synonym: "abolished protein localization to lateral cell cortex, with protein mislocalized to cytoplasm, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein localization to lateral cortex, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:vw] synonym: "protein localization to lateral cell cortex abolished, with protein mislocalized to cytoplasm, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex during vegetative growth is_a: FYPO:0007869 ! abnormal protein localization to lateral cell cortex property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:30:47Z" xsd:dateTime [Term] id: FYPO:0007871 name: decreased protein localization to lateral cell cortex, with protein distributed in cell cortex, during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the lateral cortex of a cell is decreased, and some of the protein is detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex." [PMID:34533984, PomBase:mah] synonym: "decreased protein localisation to lateral cell cortex, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to cell side, with protein distributed in cell cortex, during vegetative growth" RELATED [PomBase:vw] synonym: "decreased protein localization to lateral cell cortex, with protein distributed in cell cortex, during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein localization to lateral cortex, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:vw] synonym: "reduced protein localization to lateral cell cortex, with protein distributed in cell cortex, during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex during vegetative growth is_a: FYPO:0007869 ! abnormal protein localization to lateral cell cortex property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:31:40Z" xsd:dateTime [Term] id: FYPO:0007872 name: abolished plasma membrane flow from cell pole to lateral region def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which bulk plasma membrane flow from the cell poles to lateral regions does not occur." [PMID:34533984, PomBase:mah] synonym: "abolished bulk plasma membrane flow from cell pole to lateral region" EXACT [PomBase:mah] synonym: "abolished plasma membrane flow from cell pole to lateral region during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished plasma membrane flow from cell pole to lateral region during vegetative growth" EXACT [PomBase:mah] synonym: "plasma membrane flow from cell pole to lateral region abolished" EXACT [PomBase:mah] is_a: FYPO:0000813 ! abnormal plasma membrane organization property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:33:41Z" xsd:dateTime [Term] id: FYPO:0007873 name: abnormal exocytosis def: "A cellular process phenotype in which exocytosis is abnormal. Exocytosis is the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. A phenotype may affect exocytosis of all cargoes, or of specific cargo such as a particular protein." [GO:0006887, PomBase:mah] synonym: "exocytosis defects" EXACT [PomBase:vw] is_a: FYPO:0001720 ! abnormal transport property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:46:18Z" xsd:dateTime [Term] id: FYPO:0007874 name: decreased exocytosis at shmoo tip def: "A cellular process phenotype in which exocytosis occurs to a lower extent than normal at the shmoo tip." [PMID:34382996, PomBase:mah] synonym: "decreased exocytosis at mating projection tip" EXACT [PomBase:mah] synonym: "decreased exocytosis at shmoo projection" EXACT [PomBase:mah] synonym: "reduced exocytosis at shmoo tip" EXACT [PomBase:mah] is_a: FYPO:0007873 ! abnormal exocytosis property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:49:23Z" xsd:dateTime [Term] id: FYPO:0007875 name: normal protein localization to actin fusion focus def: "A cell phenotype in which the localization of a protein to the actin fusion focus is normal (i.e. indistinguishable from wild type)." [PMID:34382996, PomBase:mah] synonym: "normal protein localisation to actin fusion focus" EXACT [PomBase:mah] is_a: FYPO:0004096 ! normal protein localization to cytoskeleton property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T14:52:31Z" xsd:dateTime [Term] id: FYPO:0007876 name: decreased plasma membrane waviness at shmoo tip def: "A cell phenotype in which the plasma membrane is smoother than normal at the shmoo tip. Normally, the plasma membrane of one of a pair of mating cells is slack shmoo tip, forming waves instead of a smooth arc." [PMID:34382996, PomBase:mah] synonym: "abnormally smooth plasma membrane at shmoo tip" RELATED [PomBase:mah] synonym: "decreased plasma membrane waviness at mating projection tip" EXACT [PomBase:mah] synonym: "decreased plasma membrane waviness at shmoo projection" EXACT [PomBase:mah] synonym: "reduced plasma membrane waviness at shmoo tip" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular component property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-10-05T15:09:07Z" xsd:dateTime [Term] id: FYPO:0007877 name: normal regulation of translation in response to chemical def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to a chemical stimulus is normal (i.e. indistinguishable from wild type)." [PMID:34296454, PomBase:mah] synonym: "normal regulation of translation in response to chemical during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal regulation of translation in response to chemical during vegetative growth" EXACT [PomBase:mah] synonym: "normal regulation of translation in response to chemical stimulus" EXACT [PomBase:mah] synonym: "normal translational regulation in response to chemical" EXACT [PomBase:mah] is_a: FYPO:0005044 ! translation regulation phenotype during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T13:51:13Z" xsd:dateTime [Term] id: FYPO:0007878 name: decreased protein degradation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during a cellular response to methyl methanesulfonate. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PMID:34608864, PomBase:mah] synonym: "decreased protein breakdown during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolic process during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased protein degradation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein degradation during cellular response to MMS" EXACT [PomBase:mah] synonym: "reduced protein degradation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth is_a: FYPO:0002797 ! decreased protein degradation property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T13:54:31Z" xsd:dateTime [Term] id: FYPO:0007879 name: abolished protein degradation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation does not occur during a cellular response to methyl methanesulfonate. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PMID:34608864, PomBase:mah] synonym: "abolished protein breakdown during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "abolished protein catabolic process during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "abolished protein catabolism during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "abolished protein degradation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished protein degradation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein degradation during cellular response to MMS" EXACT [PomBase:mah] synonym: "protein degradation during cellular response to methyl methanesulfonate abolished" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T13:55:47Z" xsd:dateTime [Term] id: FYPO:0007880 name: normal protein degradation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PMID:34608864, PomBase:mah] synonym: "normal protein breakdown during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolic process during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein catabolism during cellular response to methyl methanesulfonate" EXACT [GO:0030163, PomBase:mah] synonym: "normal protein degradation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "normal protein degradation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein degradation during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0002800 ! normal protein degradation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T13:56:27Z" xsd:dateTime [Term] id: FYPO:0007881 name: increased duration of histone H2A phosphorylation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of histone H2A phosphorylation is longer than normal during a cellular response to methyl methanesulfonate. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be affected." [PMID:34608864, PomBase:mah] synonym: "increased duration of histone H2A phosphorylation during cellular response to methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mah] synonym: "increased duration of histone H2A phosphorylation during cellular response to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of histone H2A phosphorylation during cellular response to MMS" EXACT [PomBase:mah] synonym: "prolonged histone H2A phosphorylation during cellular response to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0002599 ! abnormal histone H2A phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T14:23:55Z" xsd:dateTime [Term] id: FYPO:0007882 name: normal protein kinase activity during cellular response to methyl methanesulfonate def: "A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate." [PMID:34608864, PomBase:mah] synonym: "normal protein kinase activity during cellular response to MMS" EXACT [PomBase:mah] is_a: FYPO:0003075 ! normal protein kinase activity property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T14:23:55Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T14:27:08Z" xsd:dateTime [Term] id: FYPO:0007883 name: decreased cleavage-dependent termination of RNA polymerase II transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cleavage-dependent termination of transcription by RNA polymerase II is abnormal. In cleavage-dependent termination, co-transcriptional secondary structure-dependent endonucleolytic cleavage triggers RNA polymerase II transcription termination; transcripts are not polyadenylated, and are subsequently rapidly degraded in the nucleus. Termination of all transcripts, or a subset of transcripts, may be affected." [PMID:34352089, PomBase:mah] synonym: "decreased cleavage-dependent premature transcription termination" NARROW [PMID:34352089] synonym: "decreased cleavage-dependent RNA polymerase II transcription termination" EXACT [PomBase:mah] synonym: "decreased cleavage-dependent termination of RNA polymerase II transcription during mitotic cell cycle" RELATED [PomBase:mah] synonym: "decreased cleavage-dependent termination of RNA polymerase II transcription during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Pac1-dependent termination of RNA polymerase II transcription" RELATED [PMID:34352089] is_a: FYPO:0006613 ! decreased termination of RNA polymerase II transcription property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-03T15:06:31Z" xsd:dateTime [Term] id: FYPO:0007884 name: abolished Lsm2-8 complex binding def: "A molecular function phenotype in which Lms2-8 complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:33378677, PomBase:mah] synonym: "Lsm2-8 complex binding abolished" EXACT [PomBase:mah] is_a: FYPO:0003591 ! abnormal protein complex binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-15T13:15:41Z" xsd:dateTime [Term] id: FYPO:0007885 name: decreased Lsm2-8 complex binding def: "A molecular function phenotype in which occurrence of Lms2-8 complex binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:33378677, PomBase:mah] synonym: "reduced Lsm2-8 complex binding" EXACT [PomBase:mah] is_a: FYPO:0003591 ! abnormal protein complex binding property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-15T13:15:41Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2021-11-15T13:16:38Z" xsd:dateTime [Term] id: FYPO:0007886 name: abolished histone H3-K9 dimethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 does not occur." [PMID:34524082, PomBase:mah] synonym: "abolished histone H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "abolished histone H3-K9 dimethylation during mitotic cell cycle" RELATED [PomBase:mah] synonym: "abolished histone H3K9me2 during vegetative growth" EXACT [PomBase:mah] synonym: "abolished histone lysine H3 K9 dimethylation during vegetative growth" EXACT [GO:0036123, PomBase:mah] synonym: "histone H3-K9 dimethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "histone H3-K9 dimethylation absent during vegetative growth" EXACT [PomBase:al] is_a: FYPO:0002566 ! abolished histone H3-K9 methylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "midori" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-11-18T08:08:22Z" xsd:dateTime [Term] id: FYPO:0007890 name: normal protein localization to kinetochore during mitotic spindle assembly checkpoint signaling def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal during mitotic spindle assembly checkpoint signaling." [PomBase:vw] is_a: FYPO:0002901 ! normal protein localization to kinetochore during vegetative growth [Term] id: FYPO:0007891 name: decreased spatial extent of mating-type region heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a smaller portion of the mating-type region than normal." [PomBase:vw] is_a: FYPO:0005849 ! decreased spatial extent of heterochromatin assembly [Term] id: FYPO:0007892 name: increased histone exchange at subtelomeric heterochromatin {EXACT="increased histone exchange at subtelomeric heterochromatin"} def: "A cellular process phenotype in which histone exchange at subtelomeric heterochromatin is increased. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [PMID:34731638, PomBase:vw] is_a: FYPO:0007472 ! abnormal histone exchange [Term] id: FYPO:0007893 name: normal protein dephosphorylation during mitotic exit def: "A cellular process phenotype in which protein dephosphorylation is normal during mitotic exit (i.e. indistinguishable from wild type). Protein dephosphorylation is the removal of a phosphate group from a protein amino acid." [PMID:12546793] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0001922 ! normal protein dephosphorylation during vegetative growth [Term] id: FYPO:0007894 name: increased histone H2B-K119 ubiquitination at subtelomeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is increased at subtelomeric heterochromatin. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PMID:34731638] is_a: FYPO:0008439 ! increased histone H2B-K119 ubiquitination during vegetative growth [Term] id: FYPO:0007895 name: increased histone H2B-K119 ubiquitination at pericentromeric heterochromatin during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is increased at pericentromeric heterochromatin. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PMID:34731638] is_a: FYPO:0008439 ! increased histone H2B-K119 ubiquitination during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-12-07T15:40:53Z" xsd:dateTime [Term] id: FYPO:0007897 name: increased protein phosphorylation during mitotic exit def: "A cellular process during mitosis in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during mitotic exit." [] is_a: FYPO:0004355 ! increased protein phosphorylation during mitosis property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-12-07T17:24:31Z" xsd:dateTime [Term] id: FYPO:0007898 name: decreased actomyosin contractile ring actin filament length def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the length of actin filaments in the contractile ring is shorter than normal." [PMID:34613787] is_a: FYPO:0004736 ! abnormal actomyosin contractile ring property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-12-07T18:06:49Z" xsd:dateTime [Term] id: FYPO:0007899 name: increased rate of protein localization to actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein to the actomyosin contractile ring is increased." [PMID:34613787, PomBase:vw] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased rate of protein localisation to actomyosin contractile ring" EXACT [PomBase:mah] synonym: "increased rate of protein localization to actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GO:1904498] synonym: "increased rate of protein localization to cytokinetic contractile ring" EXACT [PomBase:vw] synonym: "increased rate of protein localization to mitotic contractile ring" EXACT [PomBase:vw] is_a: FYPO:0002560 ! abnormal protein localization to actomyosin contractile ring property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2021-12-07T18:52:12Z" xsd:dateTime created_by: midori creation_date: 2015-10-30T15:25:35Z [Term] id: FYPO:0007901 name: increased number of R-loops def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal." [PMID:29622660] synonym: "increased level of R-loops" EXACT [] synonym: "increased level of RNA-DNA hybrids" EXACT [] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T15:14:32Z" xsd:dateTime [Term] id: FYPO:0007902 name: normal onset of cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic cytokinesis begins at the same time as normal." [PomBase:val] is_a: FYPO:0001367 ! normal cytokinesis property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T16:59:57Z" xsd:dateTime [Term] id: FYPO:0007903 name: cell lysis during mitotic interphase def: "An inviable phenotype in which a cell lyses during mitotic interphase, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PMID:19189958, PomBase:val] synonym: "cell lysis during NETO" NARROW [] synonym: "vegetative cell lysis during interphase" EXACT [] is_a: FYPO:0000647 ! vegetative cell lysis property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T17:13:40Z" xsd:dateTime [Term] id: FYPO:0007904 name: abnormal glucan synthesis def: "A cellular process phenotype in which glucan biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal glucan biosynthetic process" EXACT [] synonym: "beta-glucan synthesis defective" EXACT [] is_a: FYPO:0000860 ! abnormal metabolic process property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T17:25:24Z" xsd:dateTime [Term] id: FYPO:0007905 name: abnormal beta-glucan synthesis def: "A cellular process phenotype in which beta-glucan biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal beta-glucan biosynthetic process" EXACT [] is_a: FYPO:0007904 ! abnormal glucan synthesis property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T17:25:24Z" xsd:dateTime property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T17:33:58Z" xsd:dateTime [Term] id: FYPO:0007906 name: increased cell population growth rate during amino acid starvation def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal during amino acid starvation." [PMID:34805795, PomBase:val] synonym: "increased cell proliferation during amino acid starvation" EXACT [] is_a: FYPO:0000636 ! increased cell population growth rate property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T18:45:10Z" xsd:dateTime [Term] id: FYPO:0007907 name: increased protein phosphorylation during amino acid starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal when a cell is subject to amino acid starvation." [PMID:34805795\nPomBase\:val] is_a: FYPO:0001038 ! increased protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T18:53:55Z" xsd:dateTime [Term] id: FYPO:0007908 name: decreased protein phosphorylation during amino acid starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lesser extent than normal when a cell is subject to amino acid starvation." [PMID:34805795, PomBase:val] is_a: FYPO:0001838 ! decreased protein phosphorylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T19:03:29Z" xsd:dateTime [Term] id: FYPO:0007909 name: increased vacuolar pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured vacuolar pH is higher than normal." [PMID:34805795] xref: PomBase:val is_a: FYPO:0003755 ! abnormal vegetative cell phenotype property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-11T19:13:07Z" xsd:dateTime [Term] id: FYPO:0007910 name: increased vegetative cell shrinkage def: "A cell size phenotype in which a vegetative cell has a reduced volume or dimensions compared to a size previously observed for the same cell." [PMID:19189958, PomBase:vw] is_a: FYPO:0001127 ! abnormal cell size property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-13T15:03:43Z" xsd:dateTime [Term] id: FYPO:0007911 name: increased level of GTP-bound protein def: "A cell phenotype in which the amount of GTP-bound protein measured in the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PMID:19189958, PomBase:vw] is_a: FYPO:0001327 ! increased protein level during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-13T15:19:55Z" xsd:dateTime [Term] id: FYPO:0007912 name: normal mitochondrial distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial localization is normal." [PMID:10641037, PomBase:vw] synonym: "normal mitochondrial localization" EXACT [] is_a: FYPO:0007913 ! normal organelle localization property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-13T15:35:08Z" xsd:dateTime [Term] id: FYPO:0007913 name: normal organelle localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which organelle localization is normal." [] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-13T15:38:42Z" xsd:dateTime [Term] id: FYPO:0007914 name: mitotic sister chromatid separation during metaphase def: "A cellular process phenotype in which mitotic sister chromatid separation occurs during mitotic metaphase." [PMID:10398680, PomBase:vw] is_a: FYPO:0000416 ! premature mitotic sister chromatid separation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-13T16:00:17Z" xsd:dateTime [Term] id: FYPO:0007915 name: normal endoplasmic reticulum localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Endoplasmic Reticulum localization is normal." [PMID:10641037, PomBase:vw] is_a: FYPO:0007913 ! normal organelle localization property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-13T16:11:28Z" xsd:dateTime [Term] id: FYPO:0007916 name: increased cellular dihydrosphingosine-1-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dihydrosphingosine-1-phosphate (DHS-1P) measured in a cell is higher than normal." [PMID:35008733] synonym: "increased cellular level of DHS-1P" EXACT [] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T11:33:45Z" xsd:dateTime [Term] id: FYPO:0007917 name: decreased cellular dihydroceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dihydroceramide measured in the cell is lower than normal." [] synonym: "decreased cellular DH-cer level" EXACT [] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T11:44:57Z" xsd:dateTime [Term] id: FYPO:0007918 name: abnormal RNA 3'-end processing {xref="PomBase:vw"} def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA 3' end processing is abnormal." [] is_a: FYPO:0001553 ! abnormal RNA processing property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T11:56:32Z" xsd:dateTime [Term] id: FYPO:0007919 name: abnormal RNA alternative polyadenylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of RNA is abnormal. RNA alternative polyadenylation generates RNA molecules with variable 3'-end lengths from a given RNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites." [] is_a: FYPO:0001553 ! abnormal RNA processing property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T13:49:50Z" xsd:dateTime [Term] id: FYPO:0007920 name: decreased ncRNA alternative polyadenylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of ncRNA is decreased. ncRNA alternative polyadenylation generates RNA molecules with variable 3'-end lengths from a given RNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites." [] is_a: FYPO:0007919 ! abnormal RNA alternative polyadenylation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T13:55:44Z" xsd:dateTime [Term] id: FYPO:0007921 name: sensitive to benzamidine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to benzamidine. Cells stop growing (and may die) at a concentration of benzamidine that allows wild type cells to grow." [PomBase:vw] synonym: "sensitive to benzamidine during vegetative growth" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T16:14:05Z" xsd:dateTime [Term] id: FYPO:0007922 name: sensitive to cysteine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cysteine above normal physiological concentrations. Cells stop growing (and may die) at a concentration of cysteine that allows wild type cells to grow." [PomBase:vw] synonym: "sensitive to cysteine during vegetative growth" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T16:21:51Z" xsd:dateTime [Term] id: FYPO:0007924 name: sensitive to potassium chloride and sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of potassium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of potassium chloride and sodium dodecyl sulfate that allow wild type cells to grow." [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T16:44:47Z" xsd:dateTime [Term] id: FYPO:0007925 name: sensitive to sodium chloride and methyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of sodium chloride and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of sodium chloride and methyl methanesulfonate that allow wild type cells to grow." [PomBase:vw] synonym: "sensitive to sodium chloride and methyl methanesulfonate during vegetative growth" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T16:51:08Z" xsd:dateTime [Term] id: FYPO:0007926 name: sensitive to calcofluor and potassium chloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of calcofluor and potassium chloride. Cells stop growing (and may die) at concentrations of calcofluor and potassium chloride that allow wild type cells to grow." [PomBase:vw] synonym: "sensitive to calcofluor and potassium chloride during vegetative growth" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T17:03:09Z" xsd:dateTime [Term] id: FYPO:0007927 name: sensitive to dihydrocoumarin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to dihydrocoumarin. Cells stop growing (and may die) at a concentration of dihydrocoumarin that allows wild type cells to grow." [PomBase:vw] synonym: "sensitive to dihydrocoumarin during vegetative growth" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T17:09:37Z" xsd:dateTime [Term] id: FYPO:0007928 name: sensitive to ethylenediaminetetraacetic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethylenediaminetetraacetic acid (EDTA). Cells stop growing (and may die) at a concentration of ethylenediaminetetraacetic acid (EDTA) that allows wild type cells to grow." [PomBase:vw] synonym: "sensitive to EDTA" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T17:16:28Z" xsd:dateTime [Term] id: FYPO:0007929 name: sensitive to phloxine B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phloxine B. Cells stop growing (and may die) at a concentration of phloxine B that allows wild type cells to grow." [PomBase:vw] synonym: "sensitive to phloxine B during vegetative growth" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T18:00:23Z" xsd:dateTime [Term] id: FYPO:0007930 name: sensitive to phloxine B and hydrogen peroxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of phloxine B and hydrogen peroxide. Cells stop growing (and may die) at concentrations of phloxine B and hydrogen peroxide that allow wild type cells to grow." [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T18:09:32Z" xsd:dateTime [Term] id: FYPO:0007931 name: sensitive to egtazic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to egtazic acid. Cells stop growing (and may die) at a concentration of egtazic acid that allows wild type cells to grow." [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T18:40:25Z" xsd:dateTime [Term] id: FYPO:0007932 name: sensitive to hydroxyurea and methyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of hydroxyurea and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of hydroxyurea and methyl methanesulfonate that allow wild type cells to grow." [] synonym: "sensitive to hydroxyurea and MMS" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T18:51:49Z" xsd:dateTime [Term] id: FYPO:0007933 name: sensitive to 2,2′-dipyridyl def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2,2′-dipyridyl. Cells stop growing (and may die) at a concentration of 2,2′-dipyridyl that allows wild type cells to grow." [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T18:56:09Z" xsd:dateTime [Term] id: FYPO:0007934 name: dihydrouridine absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dihydrouridine measured in a cell is too low to detect." [PomBase:vw] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-20T19:01:40Z" xsd:dateTime [Term] id: FYPO:0007936 name: increased number of DNA breakpoint junctions def: "A cell phenotype in which the number of sites of DNA breakpoint junctions is greater than normal." [PomBase:vw] comment: DNA breakpooint junctions can be used to assess genome rearrangments. is_a: FYPO:0003546 ! increased DNA damage property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-24T16:16:36Z" xsd:dateTime [Term] id: FYPO:0007937 name: increased number of DNA breakpoint junctions during stationary phase def: "A cell phenotype in which the number of sites of DNA breakpoint junctions is greater than normal during stationary phase." [] is_a: FYPO:0007936 ! increased number of DNA breakpoint junctions property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-24T16:21:26Z" xsd:dateTime [Term] id: FYPO:0007938 name: sensitive to tea tree oil def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tea tree oil. Cells stop growing (and may die) at a concentration of tea tree oil that allows wild type cells to grow." [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-01-31T17:32:49Z" xsd:dateTime [Term] id: FYPO:0007939 name: normal chromatin loop formation during meiotic prophase I def: "A cellular process phenotype in which any chromatin loop formation is normal (i.e. indistinguishable from wild type) during the meiotic prophase I." [PomBase:val] synonym: "normal chromatin looping during meiotic prophase I" EXACT [] is_a: FYPO:0007941 ! normal chromatin organization during meiotic cell cycle property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T12:48:50Z" xsd:dateTime [Term] id: FYPO:0007940 name: normal chromatin organization def: "A cellular process phenotype in which any process of chromatin organization is normal (i.e. indistinguishable from wild type). Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [PomBase:val] is_a: FYPO:0001319 ! normal cellular process during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T12:53:47Z" xsd:dateTime [Term] id: FYPO:0007941 name: normal chromatin organization during meiotic cell cycle def: "A cellular process phenotype in which any process of chromatin organization is normal (i.e. indistinguishable from wild type) during the meiotic cell cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [] synonym: "normal chromatin organisation during meiotic cell cycle" EXACT [] is_a: FYPO:0007940 ! normal chromatin organization property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T12:55:09Z" xsd:dateTime [Term] id: FYPO:0007942 name: increased length of chromatin loops during meiotic prophase I def: "A cellular process phenotype in which chromatin loop formation during meiotic prophase I results in chromatin loops of increased length." [PomBase:val] is_a: FYPO:0007944 ! abnormal chromatin loop formation during meiotic prophase I property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T13:16:50Z" xsd:dateTime [Term] id: FYPO:0007943 name: abnormal chromatin organization during meiotic cell cycle def: "A cellular process phenotype in which any process of chromatin organization is abnormal during the meiotic cell cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [PomBase:val] is_a: FYPO:0000642 ! abnormal chromatin organization is_a: FYPO:0006759 ! abnormal meiotic chromosome organization property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T13:29:19Z" xsd:dateTime [Term] id: FYPO:0007944 name: abnormal chromatin loop formation during meiotic prophase I def: "A cellular process phenotype in which any process of chromatin loop formation is abnormal during meiotic prophase I." [PomBase:val] synonym: "abnormal chromatin looping during meiotic prophase I" EXACT [] is_a: FYPO:0007943 ! abnormal chromatin organization during meiotic cell cycle property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T13:48:05Z" xsd:dateTime [Term] id: FYPO:0007945 name: abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region during meiotic prophase I def: "A cellular process phenotype in which homologous chromosome pairing during meiosis I prophase is abnormal at a cis-acting homologous chromosome pairing region such as the sme2 locus." [PomBase:val] is_a: FYPO:0003052 ! abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T13:59:35Z" xsd:dateTime [Term] id: FYPO:0007946 name: decreased protein ubiquitination def: "A cellular process phenotype in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is decreased." [PomBase:val] is_a: FYPO:0006977 ! abnormal protein ubiquitination property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T14:11:50Z" xsd:dateTime [Term] id: FYPO:0007947 name: sensitive to echinocandin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to echinocandin. Cells stop growing (and may die) at a concentration of echinocandin that allows wild type cells to grow." [PomBase:val] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T15:31:59Z" xsd:dateTime [Term] id: FYPO:0007948 name: elongated multinucleate multiseptate spore def: "A cell phenotype in which a spore is longer than normal, is multinucleate and multiseptate." [PomBase:val] is_a: FYPO:0001123 ! elongated spore is_a: FYPO:0003342 ! elongated multinucleate cell is_a: FYPO:0005277 ! multinucleate multiseptate cell property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T15:41:14Z" xsd:dateTime [Term] id: FYPO:0007949 name: increased (1->3)-beta-D-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-beta-D-glucan measured is greater than normal." [PomBase:val] synonym: "increased (1,3)beta-D-glucan level" EXACT [] is_a: FYPO:0001194 ! increased beta-glucan level property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T16:19:55Z" xsd:dateTime [Term] id: FYPO:0007950 name: increased mating efficency during nitrogen stress def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is higher than normal when a cell is subject to nitrogen stress." [PomBase:val] is_a: FYPO:0001043 ! increased mating efficiency property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T16:26:16Z" xsd:dateTime [Term] id: FYPO:0007951 name: increased mating effciency during nitrogen starvation def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is higher than normal when a cell is subject to nitrogen starvation." [PomBase:val] is_a: FYPO:0001043 ! increased mating efficiency property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T16:27:08Z" xsd:dateTime [Term] id: FYPO:0007952 name: normal protein level during stationary phase def: "A cell phenotype in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type), during stationary phase. Total protein or a specific protein may be affected." [PomBase:val] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0004083 ! normal protein level property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T16:38:31Z" xsd:dateTime [Term] id: FYPO:0007953 name: increased spatial extent of heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the chromosome than normal." [PomBase:val] is_a: FYPO:0008425 ! increased heterochromatin assembly property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-22T16:49:45Z" xsd:dateTime [Term] id: FYPO:0007954 name: abnormal rate of microtubule depolymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which the rate or speed of microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal." [PomBase:mlr, PomBase:val] is_a: FYPO:0000902 ! abnormal microtubule depolymerization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-26T11:53:07Z" xsd:dateTime [Term] id: FYPO:0007955 name: abnormal rate of microtubule polymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which the rate or speed of microtubule polymerization, i.e. the additionl of tubulin dimers to a microtubule, is abnormal." [PomBase:mlr, PomBase:val] synonym: "abnormal rate of microtubule polymerisation during vegetative growth" EXACT [] is_a: FYPO:0004614 ! abnormal microtubule polymerization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-26T12:06:33Z" xsd:dateTime [Term] id: FYPO:0007956 name: abnormal duration of microtubule growth event def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which the duration of microtubule growth events is abnormal." [PomBase:mlr] is_a: FYPO:0000901 ! abnormal microtubule dynamics during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-26T12:12:08Z" xsd:dateTime [Term] id: FYPO:0007957 name: abnormal microtubule rescue def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule rescue (the transition from shrinkage to growth) is abnormal. The frequency of rescues as well as the organisation can be affected." [PomBase:mlr] xref: PomBase:mlr is_a: FYPO:0000901 ! abnormal microtubule dynamics during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-26T13:19:33Z" xsd:dateTime [Term] id: FYPO:0007958 name: increased rate of mitotic spindle elongation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during miotic M phase." [] is_a: FYPO:0000131 ! abnormal mitotic spindle elongation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-27T07:55:37Z" xsd:dateTime [Term] id: FYPO:0007959 name: increased rate of mitotic spindle elongation during prophase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during miotic prophase." [PomBase:mlr] is_a: FYPO:0007958 ! increased rate of mitotic spindle elongation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-27T08:00:47Z" xsd:dateTime [Term] id: FYPO:0007960 name: decreased rate of mitotic spindle elongation during prophase def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased during prophase." [PomBase:mlr] is_a: FYPO:0003268 ! decreased rate of mitotic spindle elongation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-27T08:13:11Z" xsd:dateTime [Term] id: FYPO:0007961 name: transient abrupt spindle length decrease at anaphase onset def: "A cell phenotype in which the spindle length decreases abruptly at anaphase onset." [PomBase:mlr] comment: In PMID:24239120, this is likely due to interpolar microtubules being shorter than kinetochore microtubules, so cleavage of cohesin links leads to the shrinkage in length. is_a: FYPO:0000131 ! abnormal mitotic spindle elongation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-27T09:27:10Z" xsd:dateTime [Term] id: FYPO:0007962 name: decreased mating efficiency during nitrogen starvation def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal after nitrogen removal." [PomBase:val] is_a: FYPO:0000708 ! decreased mating efficiency property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-27T17:21:14Z" xsd:dateTime [Term] id: FYPO:0007963 name: normal mating efficiency during nitrogen stress def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is normal (i.e. the same as in wild-type cells) during nitrogen limitation or poor nitrogen source." [PomBase:val] is_a: FYPO:0001147 ! normal mating efficiency property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-04-27T17:27:13Z" xsd:dateTime [Term] id: FYPO:0007965 name: increased spontaneous diploidization due to abolished sister chromatid separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells spontaneously form cells with diploid DNA content after failing chromosome segregation and consequently nuclear division. The nucleus is displaced from the cell center by actin cables, preventing chromosome cut and leading to diploidisation." [] synonym: "escape from mitotic catastrophe" BROAD [] xref: PMID:33506191 xref: PomBase:mlr is_a: FYPO:0000252 ! increased spontaneous diploidization relationship: output_of FYPO:0001946 ! abolished mitotic sister chromatid separation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T12:11:03Z" xsd:dateTime [Term] id: FYPO:0007966 name: abolished nuclear displacement from cell division site after abolished mitotic sister chromatid separation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells failing chromosome segregation and consequently nuclear division fail to displace the nucleus from the septation site. This is normally mediated by actin cables." [PMID:33506191, PomBase:mlr] is_a: FYPO:0002071 ! mislocalized nucleus during vegetative growth relationship: output_of FYPO:0001946 ! abolished mitotic sister chromatid separation relationship: output_of FYPO:0002435 ! abnormal actin cables property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T12:58:40Z" xsd:dateTime [Term] id: FYPO:0007968 name: cut with mitotic spindle microtubules protruding beyond spindle pole body def: "An inviable phenotype observed in the vegetative growth phase of the life cycle after normal chromosome separation in which pushing forces exerted by microtubules protruding from the spindle pole bodies displace one of the daughter nuclei to the site of cytokinesis. The septum then physically divides that nucleus into two parts, giving rise to inviable daughter cell." [PMID:26031557, PomBase:mlr, PomBase:vw] is_a: FYPO:0001055 ! cut following normal mitotic chromosome condensation relationship: output_of FYPO:0003787 ! long mitotic spindle microtubules protruding beyond spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T14:31:59Z" xsd:dateTime [Term] id: FYPO:0007969 name: short-lived long mitotic spindle microtubules protruding beyond spindle pole body def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form mitotic spindle microtubules that are longer than normal, extend beyond the spindle pole body and are present transiently. The protruding spindle microtubules are surrounded by an extension of the nuclear envelope." [PMID:26031557] {comment="These protrusions are short-lived and labelled by Mal3 (presumably plus ends)"} xref: PMID:26031557 xref: PomBase:mlr is_a: FYPO:0003787 ! long mitotic spindle microtubules protruding beyond spindle pole body property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T14:40:40Z" xsd:dateTime [Term] id: FYPO:0007970 name: increased rate of microtuble polymerization during vegetative growth def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a higher rate, or speed, than normal." [PMID:35293864, PomBase:mlr] is_a: FYPO:0007955 ! abnormal rate of microtubule polymerization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T15:29:18Z" xsd:dateTime [Term] id: FYPO:0007971 name: increased rate of interpolar microtubule polymerization during mitotic anaphase B def: "A microtubule cytoskeleton organization phenotype observed during mitotic anaphase B in which interpolar microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a higher rate, or speed, than normal." [PMID:35293864, PomBase:mlr] is_a: FYPO:0007970 ! increased rate of microtuble polymerization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T15:41:47Z" xsd:dateTime [Term] id: FYPO:0007972 name: decreased rate of interpolar microtubule polymerization during mitotic anaphase B def: "A microtubule cytoskeleton organization phenotype observed during mitotic anaphase B in which interpolar microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a lower rate, or speed, than normal." [PMID:35293864, PomBase:mlr] is_a: FYPO:0005703 ! decreased rate of microtubule polymerization during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T15:49:38Z" xsd:dateTime [Term] id: FYPO:0007974 name: increased rate of interpolar microtubule polymerization inside the mitotic nuclear membrane bridge def: "A microtubule cytoskeleton organization phenotype observed during mitotic anaphase B in which interpolar microtubule polymerization occurs at a higher rate, or speed, than normal for microtubules with their plus ends inside the nuclear membrane bridge formed during mitotic anaphase B." [PMID:35293864, PomBase:mlr] comment: Microtubule growth speed is normally decreased when plus ends internalise in the nuclear membrane bridge, but this occurs to a lesser extent in this phenotype is_a: FYPO:0007971 ! increased rate of interpolar microtubule polymerization during mitotic anaphase B property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T16:02:18Z" xsd:dateTime [Term] id: FYPO:0007975 name: abnormal distribution of interpolar microtubule rescue during anaphase B def: "A cellular process phenotype observed during anaphase B in which the distribution of the positions of interpolar microtubule rescues is abnormal.\nThe positions of interpolar microtubule rescues are where the transitions from shrinkage to growth occur." [PMID:35293864, PomBase:mlr] is_a: FYPO:0007957 ! abnormal microtubule rescue property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T16:06:16Z" xsd:dateTime [Term] id: FYPO:0007976 name: increased duration of interpolar microtubule growth events during anaphase B def: "A microtubule cytoskeleton organization phenotype observed during anaphase B in which the duration of interpolar microtubule growth events is longer." [PMID:35293864, PomBase:mlr] is_a: FYPO:0007956 ! abnormal duration of microtubule growth event property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T16:13:37Z" xsd:dateTime [Term] id: FYPO:0007977 name: abnormal homologous chromosome pairing during meiosis I prophase def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal during meiotic prophase I." [] is_a: FYPO:0003024 ! abnormal homologous chromosome pairing property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T16:27:37Z" xsd:dateTime [Term] id: FYPO:0007978 name: decreased homologous chromosome pairing during meiosis I prophase def: "A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased during meiotic prophase I." [] is_a: FYPO:0007977 ! abnormal homologous chromosome pairing during meiosis I prophase property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2022-05-16T16:31:54Z" xsd:dateTime [Term] id: FYPO:0007979 name: increased number of microtubules per bundle during mitotic interphase def: "A physical cellular phenotype in which cells contain interphase microtubule bundles with more microtubules than normal." [PMID:15837798, PomBase:mlr] is_a: FYPO:0005558 ! abnormal microtubule bundle [Term] id: FYPO:0007980 name: Increased microtubule overlap length in bundles during mitotic interphase: def: "A physical cellular phenotype in which cells contain interphase microtubule bundles with microtubule overlaps longer than normal." [PMID:15837798, PomBase:mlr] is_a: FYPO:0005558 ! abnormal microtubule bundle [Term] id: FYPO:0007981 name: abnormal interpolar microtubule length distribution during anaphase B def: "A physical cellular phenotype in which the distribution of lengths of interpolar microtubules in the mitotic spindle is abnormal during anaphase B." [PMID:15689489, PomBase:mlr] is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle [Term] id: FYPO:0007982 name: single microtubule bundle with aster-like microtubules def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which all detectable microtubules are present in a single bundle and are not normally crosslinked, resulting in an aster-like organisation. See PMID:15068790." [PMID:15068790, PomBase:mlr] is_a: FYPO:0002400 ! single microtubule bundle during mitotic interphase [Term] id: FYPO:0007983 name: microtubule bundles detached from the nuclear envelope def: "A physical cellular phenotype observed during mitotic interphase in which some microtubule bundles are not anchored to the nuclear membrane. See PMID:15068790" [PMID:15068790, PomBase:mlr] is_a: FYPO:0005558 ! abnormal microtubule bundle [Term] id: FYPO:0007984 name: abolished eMTOC disassembly def: "A cellular process phenotype in which equatorial microtubule organizing center (eMTOC) disassembly does not take place after cell division." [PMID:15068790, PomBase:mlr] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth [Term] id: FYPO:0007985 name: early eMTOC assembly def: "A cellular process phenotype in which equatorial microtubule organizing center (eMTOC) assembly occurs earlier than normal. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center." [PMID:15068790, PomBase:mlr] is_a: FYPO:0005690 ! abnormal eMTOC assembly [Term] id: FYPO:0007986 name: decreased protein localization to interphase microtubule bundle overlap def: "A cell phenotype observed during mitotic interphase in which the localization of a protein to the microtubule overlap of cytoplasmic microtubule bundles is decreased." [PMID:19879140, PomBase:mlr] is_a: FYPO:0006182 ! decreased protein localization to interphase microtubule [Term] id: FYPO:0007987 name: decreased rate of spindle elongation during meiotic anaphase B def: "A cellular process phenotype in which the rate, or speed, of meiotic spindle elongation is decreased during anaphase B." [PMID:32327557, PomBase:mlr] is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle [Term] id: FYPO:0007988 name: long spindle microtubules protruding beyond spindle pole body during meiosis I def: "A physical cellular phenotype observed in meiosis I in which cells form meotic spindle microtubules that are longer than normal, and extend beyond the spindle pole body. The protruding spindle microtubules are surrounded by an extension of the nuclear envelope." [PMID:32327557, PomBase:mlr] is_a: FYPO:0000734 ! abnormal meiotic spindle [Term] id: FYPO:0007989 name: abolished nuclear congression during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur because the nuclei fail to come in physical contact." [PMID:25869666, PomBase:mlr] is_a: FYPO:0003062 ! abnormal nuclear congression during mating [Term] id: FYPO:0007990 name: growth auxotrophic for isoleucine def: "Auxotrophy in which a cell is unable to synthesize isoleucine, and therefore requires isoleucine in the medium for vegetative cell growth." [PMID:35325114, PomBase:mlr] synonym: "growth auxotrophic for isoleucine during mitotic cell cycle" EXACT [] synonym: "growth auxotrophic for isoleucine during vegetative growth" EXACT [] synonym: "isoleucine auxotrophy" EXACT [] is_a: FYPO:0000128 ! auxotrophy [Term] id: FYPO:0007991 name: growth auxotrophic for valine def: "Auxotrophy in which a cell is unable to synthesize valine, and therefore requires leucine in the medium for vegetative cell growth." [PMID:35325114, PomBase:mlr] synonym: "growth auxotrophic for valine during mitotic cell cycle" EXACT [] synonym: "growth auxotrophic for valine during vegetative growth" EXACT [] synonym: "valine auxotrophy" EXACT [] is_a: FYPO:0000128 ! auxotrophy [Term] id: FYPO:0007992 name: decreased protein localization to mitotic spindle pole body during metaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during metaphase." [PMID:35286199, PomBase:mlr] synonym: "decreased protein localisation to mitotic spindle pole body during metaphase" EXACT [] synonym: "decreased protein localization to mitotic SPB during metaphase" EXACT [] is_a: FYPO:0002822 ! decreased protein localization to mitotic spindle pole body during mitosis [Term] id: FYPO:0007993 name: decreased protein localization to pericentromeric region during meiosis I def: "A cell phenotype observed during the first meiotic nuclear division in which the localization of a protein to chromatin at the pericentromeric regions is decreased." [PMID:18716626, PomBase:mlr] is_a: FYPO:0006529 ! abnormal protein localization to centromere during meiotic cell cycle [Term] id: FYPO:0007994 name: normal meiotic sister chromatid cohesion protection during meiotic anaphase I def: "A cellular process phenotype in which the cohesion protection during anaphase of the first meiotic nuclear division is normal." [PMID:18716626, PomBase:mlr] is_a: FYPO:0002094 ! normal meiotic sister chromatid cohesion [Term] id: FYPO:0007995 name: abolished protein localization to old cell tip during mitotic interphase def: "A cell phenotype in which the localization of a protein to the old cell tip does not occur during interphase of the mitotic cell cycle." [PMID:15184402, PomBase:mlr] is_a: FYPO:0003329 ! abolished protein localization to cell tip during mitotic interphase [Term] id: FYPO:0007996 name: thin actin cables def: "A physical cellular phenotype observed in mitotic interphase in which cells form actin cables that are thinner than normal. This is evidence by lower actin fluorescence signal and is likely due to the presence of fewer actin filaments than normal." [PMID:15184402, PomBase:mlr] is_a: FYPO:0002031 ! abnormal actin cable morphology [Term] id: FYPO:0007997 name: monopolar actin cortical patch localization to new end def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only the new end of a cell following cell division." [PMID:15184402, PomBase:mlr] is_a: FYPO:0001019 ! monopolar actin cortical patch localization during vegetative growth [Term] id: FYPO:0007998 name: abnormal protein localization to interphase microtubule bundle def: "A cell phenotype observed during mitotic interphase in which the localization of a protein to interphase microtubule bundles is abnormal." [PMID:15184402, PomBase:mlr] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton during vegetative growth [Term] id: FYPO:0007999 name: abolished protein localization to spindle pole body during karyogamy def: "A cell phenotype in which the localization of a protein to the spindle pole body is abolished during karyogamy." [PMID:25869666, PomBase:mlr] is_a: FYPO:0003542 ! abolished protein localization to meiotic spindle pole body [Term] id: FYPO:0008000 name: increased sensitivity to chemical in stationary phase def: "A phenotype in which cells show increased sensitivity to a chemical when the cell population is in stationary phase. Cells stop growing (and may die) at a concentration of that chemical that allows wild type cells to grow." [PMID:35618649, PomBase:mlr] is_a: FYPO:0002683 ! increased sensitivity to chemical [Term] id: FYPO:0008001 name: sensitive to menadione in stationary phase def: "A phenotype in which cells show increased sensitivity to menadione when the cell population is in stationary phase. Cells stop growing (and may die) at a concentration of menadione that allows wild type cells to grow." [PMID:35618649, PomBase:mlr] synonym: "sensitive to menadione during stationary phase" EXACT [] is_a: FYPO:0008000 ! increased sensitivity to chemical in stationary phase [Term] id: FYPO:0008002 name: cell lysis during mating def: "An inviable phenotype observed during mating in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during the process of cell fusion that occurs during mating. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PMID:35673994, PomBase:mlr] synonym: "cell lysis during cell fusion" RELATED [] synonym: "cell lysis during cellular fusion" RELATED [] is_a: FYPO:0002488 ! cell lysis [Term] id: FYPO:0008003 name: normal protein localization to site of mechanical stress def: "A cell phenotype in which the localization of a protein at a site of mechanical stress on the cell surface is normal (i.e. indistinguishable from wild type)." [PMID:34666001, PomBase:mlr] is_a: FYPO:0003627 ! normal protein localization [Term] id: FYPO:0008004 name: abolished protein localization to site of mechanical stress def: "A cell phenotype in which a protein does not localize to, and is therefore absent from, a site of mechanical stress on the cell surface where it is normally found." [PMID:34666001, PomBase:mlr] is_a: FYPO:0001375 ! abolished protein localization [Term] id: FYPO:0008005 name: normal reactive oxygen species level during stationary phase def: "A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell that is normal (i.e. indistinguishable from wild type) during stationary phase." [PomBase:mlr] synonym: "normal reactive oxygen species accumulation during stationary phase" RELATED [] synonym: "normal reactive oxygen species level in stationary phase" EXACT [] synonym: "normal ROS accumulation during stationary phase" RELATED [] synonym: "normal ROS level during stationary phase" EXACT [] synonym: "normal ROS level in stationary phase" EXACT [] is_a: FYPO:0001076 ! normal level of substance in cell [Term] id: FYPO:0008006 name: dynamic microtubule minus ends in interphase bundles def: "A microtubule cytoskeleton phenotype observed during mitotic interphase in which the microtubule minus ends are dynamic (they alternate between growth and shrinkage phases)." [PMID:21444751, PomBase:mlr] synonym: "dynamic microtubule minus ends during interphase" BROAD [] synonym: "uncapped microtubule minus ends during interphase" BROAD [] synonym: "uncapped microtubule minus ends in interphase bundles" BROAD [] is_a: FYPO:0000901 ! abnormal microtubule dynamics during vegetative growth [Term] id: FYPO:0008007 name: mitotic spindle collapse during anaphase B elongation with progressive spindle pole congression def: "A cell phenotype in which a mitotic spindle assembles and begins to elongate, but collapses during anaphase B, with the collapse being followed by the spindle poles congressing together. In some cases, this is known to be driven by depolymerisation of microtubules part of a merotelic attachment (PMID:19948483)." [PMID:19948483, PomBase:mlr] is_a: FYPO:0005722 ! mitotic spindle collapse during anaphase B elongation relationship: output_of FYPO:0004381 ! merotelic kinetochore attachment during mitosis [Term] id: FYPO:0008008 name: increased duration of cytoplasmic microtubule growth events during mitotic interphase def: "A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which the duration of cytoplasmic microtubule growth events is longer." [PMID:22363481, PomBase:mlr] synonym: "longer cytoplasmic microtubule growth events during mitotic interphase" NARROW [] synonym: "lower cytoplasmic microtubule catastrophe during mitotic interphase" NARROW [] synonym: "lower cytoplasmic microtubule catastrophe rate during mitotic interphase" NARROW [] is_a: FYPO:0007956 ! abnormal duration of microtubule growth event [Term] id: FYPO:0008009 name: abnormal interphase mitotic telomere clustering during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering is abnormal. Telomere clustering gathers telomeres during or prior to tethering to the nuclear periphery during interphase of the mitotic cell cycle." [PMID:15615848, PomBase:mlr] synonym: "abnormal interphase telomere clustering" BROAD [] synonym: "abnormal mitotic interphase telomere clustering" EXACT [] synonym: "abnormal telomere clustering during vegetative growth" EXACT [] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth [Term] id: FYPO:0008010 name: decreased RNA-dependent RNA polymerase def: "A molecular function phenotype in which the observed rate of RNA-dependent RNA polymerase activity is decreased." [PMID:15615848, PomBase:mlr] is_a: FYPO:0000663 ! decreased catalytic activity [Term] id: FYPO:0008011 name: abolished siRNA loading onto RITS complex def: "An RNA localization phenotype where the loading of siRNAs onto the RITs complex is abolished." [PMID:15615848, PomBase:mlr] synonym: "abolished recruitment of siRNA onto RITS complex" EXACT [] synonym: "decreased siRNA localization to RITS complex" EXACT [] is_a: FYPO:0000366 ! decreased RNA localization [Term] id: FYPO:0008012 name: cell sensitive to mechanical stress def: "A cell phenotype in which a vegetative cell dies at a level of mechanical stress that wild-type cells can normally withstand." [PMID:34666001, PomBase:mlr] is_a: FYPO:0003755 ! abnormal vegetative cell phenotype [Term] id: FYPO:0008013 name: normal inositol hexakisphosphate kinase activity def: "A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is normal (i.e. indistinguishable from wild type)." [PMID:35536002, PomBase:mlr] is_a: FYPO:0000660 ! normal catalytic activity [Term] id: FYPO:0008014 name: decreased protein localization to CENP-A containing chromatin during mitosis def: "A cell phenotype observed during mitotic M phase in which the localization of a protein to CENP-A containing chromatin is decreased." [PMID:35970865, PomBase:mlr] synonym: "decreased protein localisation to CENP-A containing chromatin during mitosis" EXACT [] synonym: "decreased protein localization to centromeric core region chromatin during mitosis" EXACT [] is_a: FYPO:0004313 ! decreased protein localization to CENP-A containing chromatin [Term] id: FYPO:0008015 name: decreased glucose import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glucose into the cell is decreased with respect to wild-type." [PMID:35781263, PomBase:mlr] is_a: FYPO:0001827 ! abnormal glucose import [Term] id: FYPO:0008016 name: decreased phenylalanine import during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of phenylalanine into the cell occurs to a lower extent than normal." [PMID:11069779, PomBase:mlr] synonym: "decreased L-phenylalanine import across plasma membrane" EXACT [] synonym: "decreased phenylalanine import across plasma membrane" EXACT [] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth [Term] id: FYPO:0008017 name: normal growth on glutamate nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glutamate as the nitrogen source." [PMID:7903653, PomBase:mlr] synonym: "normal cell population growth on glutamate nitrogen source" EXACT [] is_a: FYPO:0001357 ! normal vegetative cell population growth [Term] id: FYPO:0008018 name: normal growth on glutamine nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glutamine as the nitrogen source." [PMID:7903653, PomBase:mlr] synonym: "normal cell population growth on glutamine nitrogen source" EXACT [] is_a: FYPO:0001357 ! normal vegetative cell population growth [Term] id: FYPO:0008019 name: normal growth on arginine nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing arginine as the nitrogen source." [PMID:7903653, PomBase:mlr] synonym: "normal cell population growth on arginine nitrogen source" EXACT [] is_a: FYPO:0001357 ! normal vegetative cell population growth [Term] id: FYPO:0008020 name: decreased cell population growth on leucine nitrogen source def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing leucine as the nitrogen source." [PMID:7903653, PomBase:mlr] synonym: "decreased growth on leucine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on leucine nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with leucine nitrogen source" NARROW [PomBase:mlr] synonym: "reduced cell population growth on leucine nitrogen source" EXACT [PomBase:mlr] synonym: "slow cell growth on leucine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth [Term] id: FYPO:0008021 name: decreased cell population growth on alanine nitrogen source def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing alanine as the nitrogen source." [PMID:7903653, PomBase:mlr] synonym: "decreased growth on alanine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on alanine nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with alanine nitrogen source" NARROW [PomBase:mlr] synonym: "reduced cell population growth on alanine nitrogen source" EXACT [PomBase:mlr] synonym: "slow cell growth on alanine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth [Term] id: FYPO:0008022 name: abolished cell population growth on alanine nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing alanine as the nitrogen source." [PomBase:mlr] comment: Use this term for a population of cells that does not grow with alanine as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished alanine utilization" RELATED [PomBase:mlr, PomBase:vw] synonym: "abolished growth on alanine nitrogen source" BROAD [PomBase:mlr] synonym: "abolished vegetative cell population growth on alanine nitrogen source" EXACT [PomBase:mlr] synonym: "cell population growth on alanine nitrogen source abolished" EXACT [PomBase:mlr] is_a: FYPO:0001575 ! abolished vegetative cell population growth [Term] id: FYPO:0008023 name: abolished cell population growth on leucine nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing leucine as the nitrogen source." [PomBase:mlr] comment: Use this term for a population of cells that does not grow with leucine as the nitrogen source, but does grow using a different nitrogen source (a cell population that does not grow on any media would be considered inviable). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on leucine nitrogen source" BROAD [PomBase:mlr] synonym: "abolished leucine utilization" RELATED [PomBase:mlr, PomBase:vw] synonym: "abolished vegetative cell population growth on leucine nitrogen source" EXACT [PomBase:mlr] synonym: "cell population growth on leucine nitrogen source abolished" EXACT [PomBase:mlr] is_a: FYPO:0001575 ! abolished vegetative cell population growth [Term] id: FYPO:0008024 name: decreased cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in a cell (total or free) is lower than normal." [PMID:35012333] synonym: "decreased level of polyphosphate in cell" BROAD [] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: vw creation_date: 2022-11-29T14:33:15Z [Term] id: FYPO:0008025 name: normal protein localization to CENP-A containing chromatin during mitosis def: "A cell phenotype observed during mitotic M-phase in which the localization of a protein to the CENP-A containing chromatin is normal (i.e. indistinguishable from wild type)." [PMID:35970865, PomBase:mlr] synonym: "normal protein localization to CENP-A containing chromatin during mitotic M-phase" EXACT [] synonym: "normal protein localization to centromeric core region chromatin during mitosis" EXACT [] is_a: FYPO:0004314 ! normal protein localization to CENP-A containing chromatin [Term] id: FYPO:0008026 name: increased protein localization to CENP-A containing chromatin during mitosis def: "A cell phenotype observed during mitotic M-phase in which the localization of a protein to CENP-A containing chromatin is increased." [PMID:35970865, PomBase:mlr] synonym: "increased protein localisation to CENP-A containing chromatin during mitosis" EXACT [] synonym: "increased protein localisation to CENP-A containing chromatin during mitotic M-phase" EXACT [] synonym: "increased protein localization to centromeric core region chromatin during mitosis" EXACT [] is_a: FYPO:0007295 ! increased protein localization to CENP-A containing chromatin [Term] id: FYPO:0008027 name: increased rate of acid phosphatase activation during phosphate starvation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the rate of acid phosphatase activation during phosphate starvation is increased." [PMID:35012333] synonym: "increased acid phosphatase kinetics" EXACT [] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: vw creation_date: 2022-11-29T14:52:13Z [Term] id: FYPO:0008028 name: decreased rate of acid phosphatase activation during phosphate starvation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the rate of acid phosphatase activation during phosphate starvation is decreased." [PMID:35012333] synonym: "decreased acid phosphatase kinetics" EXACT [] is_a: FYPO:0004916 ! abnormal regulation of catalytic activity created_by: vw creation_date: 2022-11-29T14:52:13Z creation_date: 2022-11-29T14:55:34Z [Term] id: FYPO:0008029 name: cell lysis during hyphal growth phase def: "An inviable phenotype observed during fungal hyphal growth phase in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost." [PMID:36058798] is_a: FYPO:0002488 ! cell lysis created_by: vw creation_date: 2022-11-29T16:14:27Z [Term] id: FYPO:0008030 name: abnormal blue light photoreceptor activity def: "A phenotype in which a blue light photoreceptor activity is abnormal." [PMID:23873862] synonym: "defective blue light photoreceptor activity" EXACT [] is_a: FYPO:0000707 ! abnormal molecular function created_by: vw creation_date: 2022-11-29T16:21:38Z [Term] id: FYPO:0008031 name: abnormal blue light response def: "A cellular process phenotype in which the cellular response to blue light stimulus is abnormal." [PMID:23873862] synonym: "abnormal reponse to blue light" EXACT [] synonym: "defective blue light response" EXACT [] is_a: FYPO:0000298 ! cellular response phenotype created_by: vw creation_date: 2022-11-29T16:39:01Z [Term] id: FYPO:0008032 name: normal mitotic spindle checkpoint activation def: "A cell cycle checkpoint phenotype in which the mitotic cell cycle spindle assembly checkpoint activation is normal (i.e. indistinguishable from wild type)." [PMID:36108046] is_a: FYPO:0003762 ! normal mitotic spindle assembly checkpoint property_value: IAO:0000116 "https://github.com/pombase/fypo/issues/4243" xsd:anyURI created_by: vw creation_date: 2023-01-25T11:48:37Z [Term] id: FYPO:0008033 name: elongated mononucleate aseptate cell with cell cycle arrest in mitotic S-phase def: "A cell morphology phenotype in which a vegetative cell is elongated, has no septum, and contains one nucleus, and is arrested in mototic S-phase" [] {def="PMID:36138017"} is_a: FYPO:0005773 ! elongated mononucleate aseptate vegetative cell property_value: IAO:0000116 "https://github.com/pombase/fypo/issues/4242" xsd:anyURI created_by: vw creation_date: 2023-01-25T11:56:19Z [Term] id: FYPO:0008034 name: normal phosphorylation of RNA polymerase II C-terminal domain serine 7 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 7 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type)." [PMID:32282918] is_a: FYPO:0000776 ! normal protein phosphorylation during vegetative growth created_by: vw creation_date: 2022-11-29T17:22:41Z [Term] id: FYPO:0008035 name: ectopic CENP-A containing chromatin assembly at pericentromeric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled in the pericentromeric heterochromatin. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions." [] synonym: "CENP-A containing nucleosome speading into pericentromeric heterochromatin" EXACT [] synonym: "ectopic CENP-A containing nucleosome assembly at pericentromeric heterochromatin" EXACT [] is_a: FYPO:0005887 ! ectopic CENP-A containing chromatin assembly created_by: vw creation_date: 2023-01-25T12:21:59Z [Term] id: FYPO:0008036 name: increased nucleosome occupancy at CENP-A boundary def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at the CENP-A boundary. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:36200823] is_a: FYPO:0007655 ! increased nucleosome occupancy created_by: vw creation_date: 2023-01-25T12:40:30Z [Term] id: FYPO:0008037 name: decreased rate of transcription elongation from RNA polymerase II promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of elongation of a transcript initiated from an RNA polymerase II promoter is abnormal." [] is_a: FYPO:0004065 ! abnormal transcription elongation from RNA polymerase II promoter created_by: vw creation_date: 2023-01-25T13:23:05Z [Term] id: FYPO:0008038 name: abolished histone H3-K4 trimethylation during mitosis def: "A cellular process phenotype observed in mitosis in which trimethylation of lysine at position 4 of histone H3 does not occur." [] is_a: FYPO:0004126 ! abolished histone H3-K4 trimethylation during vegetative growth created_by: vw creation_date: 2023-01-25T13:43:57Z [Term] id: FYPO:0008039 name: decreased 1-phosphatidylinositol-4-phosphate 5-kinase activity def: "A molecular function phenotype in which the observed rate of a decreased 1-phosphatidylinositol-4-phosphate 5-kinase activity is decreased." [PMID:10950958] is_a: FYPO:0000663 ! decreased catalytic activity created_by: vw creation_date: 2022-11-29T19:32:07Z [Term] id: FYPO:0008040 name: increased cellular phosphatidylinositol-4,5-bisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in a cell is higher than normal." [] synonym: "increased phosphatidylinositol-4,5-bisphosphate level in cell" EXACT [] is_a: FYPO:0001286 ! increased cellular phosphoinositide level created_by: vw creation_date: 2022-11-29T19:45:09Z [Term] id: FYPO:0008041 name: decreased cellular phosphatidylinositol-4,5-bisphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in a cell is lower than normal." [] synonym: "decreased phosphatidylinositol-4,5-bisphosphate level in cell" EXACT [] is_a: FYPO:0005588 ! decreased cellular phosphoinositide level created_by: vw creation_date: 2022-11-29T19:45:09Z creation_date: 2022-11-29T19:58:17Z [Term] id: FYPO:0008042 name: abolished establishment or maintenance of actin cytoskeleton polarity during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of actin cytoskeleton polarity is abolished." [] synonym: "abolished actin cytoskeleton polarisation during vegetative growth" RELATED [PomBase:mah] synonym: "abolished actin cytoskeleton polarization during vegetative growth" RELATED [] is_a: FYPO:0000198 ! abnormal establishment or maintenance of actin cytoskeleton polarity during vegetative growth created_by: vw creation_date: 2011-04-13T03:41:10Z creation_date: 2022-11-29T20:02:43Z [Term] id: FYPO:0008043 name: increased protein localization to nucleus during stationary phase def: "A cell phenotype observed in which the localization of a protein to the nucleus is increased during stationary phase." [PMID:36174923] is_a: FYPO:0004456 ! increased protein localization to nucleus created_by: vw creation_date: 2022-11-29T20:10:39Z [Term] id: FYPO:0008044 name: swollen elongated multinucleate aseptate vegetative cell with more than four nuclei def: "A cell morphology phenotype in which a vegetative cell is swollen, elongated, has no septum, and contains more than four nucleus. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal." [PMID:10545452] comment: Multiple nuclear division cycles can cause arrested cells to accumulate up to 32 nuclei. is_a: FYPO:0002051 ! swollen elongated multinucleate aseptate vegetative cell is_a: FYPO:0008045 ! elongated vegetative cell with more than four nuclei created_by: vw creation_date: 2022-11-30T12:15:08Z [Term] id: FYPO:0008045 name: elongated vegetative cell with more than four nuclei def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than four nuclei, is longer than normal, and has a greater length:diameter ratio than normal." [] is_a: FYPO:0000133 ! elongated multinucleate vegetative cell created_by: vw creation_date: 2022-11-30T12:33:27Z [Term] id: FYPO:0008046 name: decreased sexual agglutination in response to blue light def: "A cell population phenotype that reflects decreased occurrence of sexual agglutination in response to blue light." [PMID:23873862] synonym: "decreased conjugation with cellular fusion in response to blue light" EXACT [] is_a: FYPO:0000003 ! cell population phenotype created_by: vw creation_date: 2022-11-30T12:58:52Z [Term] id: FYPO:0008047 name: decreased histone H3-K4 dimethylation at centromere during meiosis def: "A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is decreased at the centromere." [] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: vw creation_date: 2023-01-25T13:46:16Z [Term] id: FYPO:0008048 name: increased histone H3-K4 dimethylation at centromere during meiosis def: "A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is increased at the centromere." [] is_a: FYPO:0008049 ! increased histone H3-K4 dimethylation during meiosis created_by: vw creation_date: 2023-01-25T14:40:53Z [Term] id: FYPO:0008049 name: increased histone H3-K4 dimethylation during meiosis def: "A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is increased." [] is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: vw creation_date: 2023-01-25T14:43:16Z [Term] id: FYPO:0008050 name: abolished histone H3-K4 methylation during meiosis def: "A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is abolished." [] is_a: FYPO:0006459 ! abnormal protein modification during meiotic cell cycle created_by: vw creation_date: 2023-01-25T14:50:38Z [Term] id: FYPO:0008051 name: decreased ubiquitin ligase activity def: "A molecular function phenotype in which the observed rate of ubiquitin ligase activity is decreased." [PMID:28572513] is_a: FYPO:0001912 ! abnormal ubiquitin ligase activity property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T10:53:57Z" xsd:dateTime [Term] id: FYPO:0008052 name: increased histone H3-K4 dimethylation during mitosis def: "A cellular process phenotype observed in mitosis in which the dimethylation of lysine at position 4 of histone H3 occurs to a greater extent than normal." [] is_a: FYPO:0005225 ! increased histone H3-K4 dimethylation during vegetative growth created_by: vw creation_date: 2023-01-25T14:56:15Z [Term] id: FYPO:0008053 name: decreased intron acceptor binding def: "A molecular function phenotype in which an interaction between a protein and mRNA intron acceptor is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one." [] synonym: "'decreased 3' intron binding'" EXACT [] is_a: FYPO:0002134 ! decreased protein-RNA interaction property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T10:59:49Z" xsd:dateTime [Term] id: FYPO:0008054 name: decreased homocitrate synthase inhibition by L-lysine def: "A molecular function phenotype in which the observed rate of homocitrate synthase is increased, due to the absence of lysine inhibition." [PMID:20089861] synonym: "feedback inhibition insensitive" BROAD [] is_a: FYPO:0000662 ! increased catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T11:09:33Z" xsd:dateTime [Term] id: FYPO:0008055 name: decreased Glc2Man9GlcNAc2 oligosaccharide glucosidase activity def: "A molecular function phenotype in which the observed rate of a Glc2Man9GlcNAc2 oligosaccharide glucosidase activity is decreased." [PMID:23609449] is_a: FYPO:0000663 ! decreased catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:01:17Z" xsd:dateTime [Term] id: FYPO:0008056 name: abolished poly(A)-specific ribonuclease activity def: "A molecular function phenotype in which a poly(A)-specific ribonuclease activity is absent." [PMID:19307292] is_a: FYPO:0006301 ! abolished ribonuclease activity property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:10:35Z" xsd:dateTime [Term] id: FYPO:0008057 name: abnormal enzyme processivity def: "A molecular function phenotype in which the observed ability of an enzyme to catalyze consecutive reactions without releasing the substrate (i.e. template) is abnormal." [] {def="PMID:19307292"} is_a: FYPO:0000661 ! abnormal catalytic activity property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:19:00Z" xsd:dateTime [Term] id: FYPO:0008058 name: increased polyA ribonuclease processivity def: "A molecular function phenotype in which the observed ability of a polyA robonuclease to catalyze consecutive reactions without releasing the substrate (i.e. template) is abnormal." [PMID:19307292] is_a: FYPO:0008057 ! abnormal enzyme processivity property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:26:52Z" xsd:dateTime [Term] id: FYPO:0008059 name: decreased K48-linked polyubiquitin binding def: "A molecular function phenotype in which the binding of a protein to K48-linked polyubiquitin occurs to a lower extent than normal." [PMID:16138082] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased K48-linked polyUb binding" EXACT [] is_a: FYPO:0001645 ! decreased protein-protein interaction property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:38:03Z" xsd:dateTime [Term] id: FYPO:0008060 name: normal mono ubiquitin binding def: "A molecular function phenotype in which the binding of one protein to a ubiquitin monomer is normal (i.e. indistinguishable from wild type)." [PMID:16138082] comment: This term can be used for any protein-protein interaction that is tested in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. is_a: FYPO:0000703 ! normal protein-protein interaction property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:43:41Z" xsd:dateTime [Term] id: FYPO:0008061 name: abolished phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II does not occur." [PMID:1902677] is_a: FYPO:0007410 ! abnormal RNA polymerase II C-terminal domain phosphorylation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:50:15Z" xsd:dateTime [Term] id: FYPO:0008062 name: increased chromatin binding at centromere central core def: "A molecular function phenotype in which occurrence of chromatin binding to the chromatin central core by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin." [PMID:15908586] is_a: FYPO:0002980 ! increased chromatin binding property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T15:57:24Z" xsd:dateTime [Term] id: FYPO:0008063 name: decreased immediate intracellular calcium spike following osmotic shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following osmotic shock. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:36200871] is_a: FYPO:0001462 ! altered cellular calcium level property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-22T16:02:14Z" xsd:dateTime [Term] id: FYPO:0008064 name: decreased mating efficiency during phosphate starvation def: "A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal after phosphate removal." [PMID:36779416] is_a: FYPO:0000708 ! decreased mating efficiency property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-06T12:47:10Z" xsd:dateTime [Term] id: FYPO:0008065 name: decreased sporulation frequency during phosphate starvation def: "A cell population phenotype in which the frequency of occurrence of ascospore formation is decreased after phosphate removal." [] is_a: FYPO:0000584 ! decreased sporulation frequency property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-06T12:53:03Z" xsd:dateTime [Term] id: FYPO:0008066 name: abolished cell cycle arrest in mitotic G1 phase in response to phosphate starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is no longer arrested during G1 phase when phosphate is removed. Arrest may either occur under conditions where arrest is not a normal occurrence, or may progress differently from normal under conditions where arrest normally does take place." [PMID:36779416] is_a: FYPO:0005097 ! abnormal cell cycle arrest in mitotic G1 phase property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-06T13:08:24Z" xsd:dateTime [Term] id: FYPO:0008067 name: constricted chained mitochondrion def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitochondrion is abnormally hyperconstricted at the fission sites and has a chained \"beads-on-a-string\" appearance." [PMID:37540145] is_a: FYPO:0000056 ! mitochondria fused property_value: creation_dat "2023-08-16T10:22:42Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008068 name: increased spatial extent of chromatin silencing at silent mating-type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is observed over an increased portion of the mating-type region." [PMID:18030666] is_a: FYPO:0004376 ! increased chromatin silencing at silent mating-type cassette property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-06T14:51:51Z" xsd:dateTime [Term] id: FYPO:0008069 name: increased spatial extent of histone H3-K9 methylation at mating type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at the mating type locus is observed over an increased portion of the mating-type region." [PMID:18030666] is_a: FYPO:0005065 ! increased histone H3-K9 methylation at mating type locus during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-06T15:01:17Z" xsd:dateTime [Term] id: FYPO:0008070 name: normal histone H3-K9 methylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 in centromeric regions is normal (i.e. indistinguishable from wild type)." [PMID:19394293] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-06T15:19:23Z" xsd:dateTime [Term] id: FYPO:0008071 name: normal spatial extent of histone H3-K9 methylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs over the same portion of the chromosome as normal (i.e. indistinguishable from wild type)." [PMID:19394293] synonym: "normal histone H3-K9 methylation spreading during vegetative growth" EXACT [] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T13:52:29Z" xsd:dateTime [Term] id: FYPO:0008072 name: normal spatial extent of histone H3-K9 methylation at peri-centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs over the same portion of the peri-centromere as normal (i.e. indistinguishable from wild type)." [PMID:19394293] synonym: "normal histone H3-K9 methylation spreading at peri-centromere during vegetative growth" EXACT [] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth is_a: FYPO:0008071 ! normal spatial extent of histone H3-K9 methylation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T13:58:43Z" xsd:dateTime [Term] id: FYPO:0008073 name: normal RITS complex assembly def: "A cellular process phenotype in which the assembly of a RITS complex in the vegetative growth phase of the life cycle is normal (i.e. indistinguishable from wild type)." [PMID:19394293] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T14:06:51Z" xsd:dateTime [Term] id: FYPO:0008074 name: increased protein localization to medial cortical node during interphase def: "A cell phenotype in which the localization of a protein to the medial cortical nodes is increased during mitotic interphase." [PMID:10930468] is_a: FYPO:0007156 ! increased protein localization to medial cortical node property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T14:12:22Z" xsd:dateTime [Term] id: FYPO:0008075 name: increased protein localization to cell cortex of cell tip during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is increased." [PMID:25959226] is_a: FYPO:0006875 ! abnormal protein localization to cell cortex of cell tip during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T14:22:07Z" xsd:dateTime [Term] id: FYPO:0008076 name: decreased phosphatidylinositol-4,5-bisphosphate binding def: "A molecular function phenotype in which occurrence of phosphatidylinositol-4,5-bisphosphate by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:25959226] comment: This term can mean that the mutated gene product itself binds one or more phospholipids less than wild type, or that a mutation in one gene decreases phospholipid binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "decreased PI(4,5)P2 binding" EXACT [] synonym: "decreased PIP2 binding" EXACT [] synonym: "decreases PtdInsP binding" EXACT [] is_a: FYPO:0005307 ! decreased phospholipid binding property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T14:26:22Z" xsd:dateTime [Term] id: FYPO:0008077 name: decreased phosphatidylserine binding def: "A molecular function phenotype in which occurrence of phosphatidylserine binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:25959226] comment: This term can mean that the mutated gene product itself binds one or more phospholipids less than wild type, or that a mutation in one gene decreases phospholipid binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0005307 ! decreased phospholipid binding property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-03-07T14:34:39Z" xsd:dateTime [Term] id: FYPO:0008078 name: normal meiotic sister kinetochore association in meiotic metaphase I def: "A cellular process phenotype in which meiotic sister kinetochore association in meiotic metaphase I, is normal (i.e. indistinguishable from wild type)." [PMID:34851403] is_a: FYPO:0007078 ! normal meiotic cell cycle process property_value: creation_dat "2023-08-16T10:57:30Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008079 name: normal inositol heptakisphosphate 5-kinase activity def: "A molecular function phenotype in which the observed rate and other catalytic properties of a inositol heptakisphosphate 5-kinase are normal (i.e. indistinguishable from wild type)." [PMID:36468882] is_a: FYPO:0000660 ! normal catalytic activity property_value: creation_dat "2023-08-16T12:37:28Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008080 name: decreased inositol heptakisphosphate 5-kinase activity def: "A molecular function phenotype in which the observed rate of a heptakisphosphate 5-kinase is decreased." [PMID:36468882] is_a: FYPO:0000663 ! decreased catalytic activity property_value: creation_dat "2023-08-16T12:39:53Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008081 name: decreased vegetative cell population growth when co-cultured with wild-type cells def: "A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle when the population is co-cultured with wild-type cells. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both." [PMID:36302945] synonym: "adaptive growth" RELATED [] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-05-12T10:56:00Z" xsd:dateTime [Term] id: FYPO:0008082 name: abnormal autophagy def: "A cellular process phenotype in which autophagy is abnormal. Autophagy is the pathway by which cells digest parts of their own cytoplasm." [PMID:35406650] is_a: FYPO:0000628 ! abnormal cellular process property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T08:25:03Z" xsd:dateTime [Term] id: FYPO:0008083 name: abnormal reticulophagy def: "A cellular process phenotype in which autophagic degradation of the endoplasmic reticulum is abnormal." [] is_a: FYPO:0008082 ! abnormal autophagy property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T08:36:39Z" xsd:dateTime [Term] id: FYPO:0008084 name: abolished reticulophagy during nitrogen starvation def: "A cellular process phenotype in which autophagic degradation of the endoplasmic reticulum is abolished during nitrogen starvation." [PMID:37191320] is_a: FYPO:0008083 ! abnormal reticulophagy property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T08:47:18Z" xsd:dateTime [Term] id: FYPO:0008085 name: abnormal nucleophagy def: "A cellular process phenotype in which autophagic degradation of the nucleus is abolished." [] {def="PMID:37191320"} is_a: FYPO:0008082 ! abnormal autophagy property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T09:00:36Z" xsd:dateTime [Term] id: FYPO:0008086 name: abolished nucleophagy during nitrogen starvation def: "A cellular process phenotype in which autophagic degradation of the nucleus during nitrogen starvation is abolished ." [PMID:37191320] is_a: FYPO:0008085 ! abnormal nucleophagy property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T09:32:05Z" xsd:dateTime [Term] id: FYPO:0008087 name: decreased nucleophagy during nitrogen starvation def: "A cellular process phenotype in which autophagic degradation of the nucleus during nitrogen starvation is decreased." [PMID:37191320] is_a: FYPO:0008386 ! decreased nucleophagy property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T09:34:03Z" xsd:dateTime [Term] id: FYPO:0008088 name: abolished chromosome oscillation at meiotic metaphase I def: "A cellular process phenotype in which the oscillations of homologous chromosomes which occurs at meiotic metaphase I is abolished." [PMID:33529549] synonym: "loss of chromosome oscillation at meiotic metaphase I" EXACT [] is_a: FYPO:0008098 ! abnormal chromosome oscillation at meiotic metaphase I property_value: creation_dat "2023-08-16T13:15:19Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008089 name: abnormal mitochondrial fusion def: "A cellular process phenotype in which mitochondrion fusion is abnormal." [PMID:37590302] is_a: FYPO:0000628 ! abnormal cellular process property_value: creation_dat "2023-08-31T16:44:05Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008090 name: normal onset of mitotic anaphase B def: "A cellular process phenotype in which mitotic anaphase begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events." [] is_a: FYPO:0000627 ! normal cellular process property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T10:29:56Z" xsd:dateTime [Term] id: FYPO:0008091 name: increased polyadenylated rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature, polyadenylated rRNA measured in a cell is higher than normal." [PMID:36794724] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. is_a: FYPO:0005996 ! altered rRNA or precursor level is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth property_value: creation_dat "2023-08-31T16:49:14Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008092 name: growth auxotrophic for para-hydroxy benzoic acid def: "Auxotrophy in which a cell is unable to synthesize para-hydroxy benzoic acid and therefore requires para-hydroxy benzoic acid in the medium for vegetative cell growth." [PMID:37156397] is_a: FYPO:0000128 ! auxotrophy property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-07T10:36:30Z" xsd:dateTime [Term] id: FYPO:0008093 comment: Added in error, removed in same session. is_obsolete: true [Term] id: FYPO:0008094 name: increased number of Rpa2 foci during vegetative growth def: "A cell phenotype in which the number of sites at which the protein Rpa2 accumulates is greater than normal during vegetative growth." [PMID:37237082] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T11:52:25Z" xsd:dateTime [Term] id: FYPO:0008095 name: increased cell size during G0 def: "A cell size phenotype in which a cell has a volume that is larger than normal during G0." [PMID:37128864] is_a: FYPO:0008096 ! increased cell size property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T11:57:07Z" xsd:dateTime [Term] id: FYPO:0008096 name: increased cell size def: "A cell size phenotype in which a cell has a volume that is larger than normal." [PMID:26566110] is_a: FYPO:0001127 ! abnormal cell size property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T11:59:56Z" xsd:dateTime [Term] id: FYPO:0008097 name: separation of sister chromatids in stationary phase def: "A cellular process phenotype in which sister chromatids partially separate in G2 arrest after glucose starvation (i.e. stationary phase)." [] is_a: FYPO:0000641 ! abnormal chromosome organization property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T12:06:18Z" xsd:dateTime [Term] id: FYPO:0008098 name: abnormal chromosome oscillation at meiotic metaphase I def: "A cellular process phenotype in which the oscillations of homologous chromosomes which occurs at meiotic metaphase I is reduced." [PMID:33529549] synonym: "aberrant chromosome oscillation at meiotic metaphase I" EXACT [] is_a: FYPO:0004159 ! abnormal homologous chromosome segregation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T12:25:49Z" xsd:dateTime [Term] id: FYPO:0008099 name: abolished homologous chromosome movement at anaphase A def: "A cellular process phenotype in which the homologous chromosomes do not migrate toward the spindle pole in spindle elongation phase I (anaphase A)." [] is_a: FYPO:0004159 ! abnormal homologous chromosome segregation property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T12:29:59Z" xsd:dateTime [Term] id: FYPO:0008100 name: increased polyadenylated 5S rRNA level during cellular response to phosphate starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature, polyadenylated 5S rRNA measured in a cell is higher than normal during phosphate starvation." [PMID:36794724] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. is_a: FYPO:0008091 ! increased polyadenylated rRNA level property_value: creation_dat "2023-08-31T16:52:27Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008101 name: altered tRNA or precursor level during vegetative growth def: "A cell phenotype in which the amount of tRNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle." [] {comment="PMID:36794724"} comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. is_a: FYPO:0005999 ! altered tRNA or precursor level property_value: creation_dat "2023-08-31T16:56:39Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008102 name: increased tRNA level during cellular response to phosphate starvation def: "A cell phenotype in which the amount of tRNA measured in a cell is increased from normal when the cell is in the vegetative growth phase of the life cycle during phosphate starvation." [PMID:36794724] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "increased tRNA production during cellular response to phosphate starvation" RELATED [] is_a: FYPO:0008101 ! altered tRNA or precursor level during vegetative growth property_value: creation_dat "2023-08-31T17:04:56Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008103 name: normal protein localization to perinuclear endoplasmic reticulum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the preinuclear endoplasmic reticulum is normal (i.e. indistinguishable from wild type)." [PMID:36799444] is_a: FYPO:0006378 ! normal protein localization to endoplasmic reticulum during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T15:20:51Z" xsd:dateTime [Term] id: FYPO:0008104 name: normal protein localization to cortical endoplasmic reticulum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical endoplasmic reticulum is normal (i.e. indistinguishable from wild type)." [PMID:36799444] is_a: FYPO:0006378 ! normal protein localization to endoplasmic reticulum during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-16T15:22:38Z" xsd:dateTime [Term] id: FYPO:0008105 name: increased chromatin mobility during stationary phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which chromatin moves within the nucleus to a greater extent than normal during stationary phase." [PMID:37128864] is_a: FYPO:0007517 ! increased chromatin mobility property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-20T09:55:37Z" xsd:dateTime [Term] id: FYPO:0008106 name: increased cell size during stationary phase def: "A cell size phenotype in which a cell has a volume that is larger than normal during stationary phase." [PMID:37128864] is_a: FYPO:0008096 ! increased cell size property_value: http://purl.org/dc/elements/1.1/creator "vw253" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-20T09:57:59Z" xsd:dateTime [Term] id: FYPO:0008107 name: decreased protein localization to nucleus during stationary phase def: "A cell phenotype in which the localization of a protein to the nucleus is decreased during stationary phase." [PMID:37128864] is_a: FYPO:0004455 ! decreased protein localization to nucleus property_value: creation_dat "2023-06-26T10:15:32Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008108 name: normal mitochondrial inheritance def: "A phenotype in which mitochondrial is normal (i.e. indistinguishable from wild type)." [] {comment="PMID:15710398"} is_a: FYPO:0000627 ! normal cellular process property_value: creation_dat "2023-08-31T17:12:24Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008109 name: abolished U6 2'-O-snRNA methylation at residue A64 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of the adenine residue at position 64 in an U6 snRNA molecule is abolished." [PMID:37403782] is_a: FYPO:0003621 ! abolished U6 2'-O-snRNA methylation property_value: creation_dat "2023-07-11T12:16:24Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008110 name: decreased U6 2'-O-snRNA methylation at residue A64 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of the adenine residue at position 64 in an U6 snRNA molecule is decreased." [PMID:37403782] is_a: FYPO:0000372 ! decreased RNA modification is_a: FYPO:0008111 ! abnormal snRNA modification property_value: creation_dat "2023-07-11T12:20:26Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008111 name: abnormal snRNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which snRNA modification is abnormal. All snRNA modification may be abnormal, or one or more specific snRNA modifications may be selectively affected." [PMID:37403782] is_a: FYPO:0000370 ! abnormal RNA modification property_value: creation_dat "2023-07-11T12:26:19Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008112 name: abnormal U6 snRNP assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of U6 snRNP complex assembly is abnormal." [PMID:37403782] is_a: FYPO:0003628 ! abnormal ribonucleoprotein complex assembly property_value: creation_dat "2023-07-11T12:31:29Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008113 name: increased intron retention def: "A cellular process phenotype in which introns are retained at some, but not all introns at a higher level with increased frequency. Weak donor sequences are more affected." [PMID:37403782] is_a: FYPO:0003244 ! decreased mRNA splicing, via spliceosome, intron-specific property_value: creation_dat "2023-07-11T12:34:21Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008114 name: sensitive to amiloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amiloride. Cells stop growing (and may die) at a concentration of amiloride that allows wild type cells to grow." [PMID:15537393] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth property_value: creation_dat "2023-07-11T12:43:36Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008115 name: increased cell population growth on sorbitol carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing sorbitol as the carbon source." [PMID:15537393] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. is_a: FYPO:0004557 ! increased vegetative cell population growth property_value: creation_dat "2023-07-11T13:07:58Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008116 name: decreased phosphoglycerate mutase activity def: "A molecular function phenotype in which the observed rate of a phosphoglycerate mutase activity is decreased." [PMID:11106417] is_a: FYPO:0000663 ! decreased catalytic activity property_value: creation_dat "2023-07-11T13:25:54Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008117 name: abnormal de novo SAGA complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which de novo assembly of the SAGA complex is abnormal." [PMID:31748520] comment: Note that this term refers to the abnormal biogenesis of the complex, i.e. the process of building the complex from individual subunits. For assays identifyion alterations in complex subunit composition use 'abnormal protein complex composition FYPO:0005003' or 'abnormal protein-protein interaction" (FYPO:0000704) or their descendants. is_a: FYPO:0000447 ! abnormal protein-containing complex assembly property_value: creation_dat "2023-09-05T16:22:58Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008118 name: decreased splicing of introns with branch point-distant 3’-splice site def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome is decreased for specific introns with longer than average (>21 bp) branch site to acceptor distance." [PMID:36095128] synonym: "Inefficient excision of introns with branch point (BP)-distant 3’-splice site (ss)" EXACT [] is_a: FYPO:0003244 ! decreased mRNA splicing, via spliceosome, intron-specific property_value: creation_dat "2023-08-31T18:23:05Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008119 name: normal morphology during phosphate starvation def: "A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is subject to phophate starvation." [PMID:36794724] is_a: FYPO:0000672 ! normal cell morphology property_value: creation_dat "2023-08-31T18:35:50Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008120 name: decreased protein level in SAGA complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the SAGA complex is lower than normal." [PMID:31748520] is_a: FYPO:0005003 ! abnormal protein complex composition property_value: creation_dat "2023-09-05T16:37:08Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008121 name: decreased protein level in NuA4 complex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the NuA4 complex is lower than normal." [PMID:31748520] is_a: FYPO:0005003 ! abnormal protein complex composition property_value: creation_dat "2023-09-05T16:40:45Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008122 name: increased mitochondrial fusion def: "A cellular process phenotype in which mitochondrion fusion is increased." [] {def="PMID:37590302"} is_a: FYPO:0008089 ! abnormal mitochondrial fusion property_value: creation_dat "2023-09-05T16:53:41Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008123 name: loss of viability in stationary phase upon phosphate starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase, when cells the population are subject to phosphate starvation." [PMID:36794724] synonym: "decreased chronological lifespan of phosphate-starved cells" EXACT [] is_a: FYPO:0000245 ! loss of viability in stationary phase property_value: creation_dat "2023-09-05T16:57:32Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008124 name: increased nuclear envelope SPB fenestra size def: "A abnormal nuclear envelope organization phenotype in which SPB fenestra in the nuclear envelope are larger than normal. SPB fenestra are the result of SPB extrusion." [PMID:37783794] is_a: FYPO:0000815 ! abnormal nuclear envelope organization property_value: creation_dat "2023-10-06T15:36:37Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008125 name: increased duration of nuclear envelope SPB fenestra def: "A abnormal nuclear envelope organization phenotype in which SPB fenestra in the nuclear envelope are present for longer than normal." [PMID:37783794] synonym: "persistent nuclear envelope fenestra" EXACT [] is_a: FYPO:0000815 ! abnormal nuclear envelope organization property_value: creation_dat "2023-10-06T15:40:43Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008126 name: cytoplasmic protein mislocalized to nucleoplasm during mitotic M-phase def: "A cell phenotype in which a protein that is normally found only in the cytoplasm is observed in the nucleoplasm during mitotic M-phase." [PMID:37783794] is_a: FYPO:0003453 ! protein mislocalized to nucleus property_value: creation_dat "2023-10-06T15:48:37Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008127 name: ribosome mislocalized to nucleoplasm def: "A cell phenotype where a ribosome is mislocalized to the nucleoplasm in the vegetative growth phase of the life cycle." [PMID:37783794] is_a: FYPO:0006329 ! abnormal organelle localization property_value: creation_dat "2023-10-06T15:54:10Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008128 name: decreased vegetative cell population growth on low glucose def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing low glucose. This term refers to situations where glucose is below 0.2%." [PMID:37859837] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: creation_dat "2023-11-02T15:13:12Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008129 name: increased tRNA guanosine N2,N2-dimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of two methyl groups to the N2 position of a guanine residue in a tRNA molecule is increased. Normally, two methyl groups are transferred to the G26 residue." [] is_a: FYPO:0001766 ! abnormal tRNA methylation property_value: creation_dat "2023-11-02T15:31:36Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008130 name: increased stop codon readthrough def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translational readthough of a stop codon increases during cytoplasmic translation." [] is_a: FYPO:0003124 ! abnormal cytoplasmic translation property_value: creation_dat "2023-11-02T15:36:28Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008131 name: normal growth site selection after cell division def: "A phenotype in which the selection of the new growth site is at the old cell end ." [PMID:14663827] is_a: FYPO:0000627 ! normal cellular process property_value: creation_dat "2023-11-02T15:42:04Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008132 name: increased calcium signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which calcium signaling is increased." [] synonym: "increased calcium signalling" EXACT [] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth property_value: creation_dat "2023-11-02T15:55:57Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008133 name: decreased phosphatidylinositol-4-phosphate level in the Golgi def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell is lower than normal in the Golgi." [PMID:37815455] is_a: FYPO:0006775 ! decreased cellular phosphatidylinositol-4-phosphate level property_value: creation_dat "2023-11-02T15:59:47Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008134 name: normal cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in the cell is normal (i.e. indistinguishable from wild type)." [PMID:37783794] is_a: FYPO:0001076 ! normal level of substance in cell property_value: creation_dat "2023-11-02T16:03:03Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008135 name: decreased protein localization tomitotic spindle pole body during G1/S def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during G1/S ofinterphase." [] {comment="PMID:37783794"} is_a: FYPO:0002821 ! decreased protein localization to mitotic spindle pole body during interphase property_value: creation_dat "2023-11-02T16:09:30Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008136 name: normal stop codon readthrough def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translational readthough of a stop codon is normal (i.e. indistinguishable from wild-type) during cytoplasmic translation." [PMID:37805140] is_a: FYPO:0000627 ! normal cellular process property_value: creation_dat "2023-11-10T16:13:10Z" xsd:dateTime created_by: vw [Term] id: FYPO:0008137 name: decreased size and number of lipid droplets def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lipid droplets are smaller and more numerous than normal." [PMID:35658118] is_a: FYPO:0000808 ! abnormal lipid droplet organization created_by: vw creation_date: 2023-12-29T18:29:47Z [Term] id: FYPO:0008138 name: normal nucleocytoplasmic transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleocytoplasmic tranport is normal (i.e. indistinguishable from wild type). Nucleocytoplasmic transportport is the directed movement of any substance into or out of the nucleus; import or export of all substances or a specific substance may be affected." [PMID:11839792] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: vw creation_date: 2023-12-29T18:52:02Z [Term] id: FYPO:0008139 name: dilated endoplasmic reticulum lumen def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum lumen is larger than normal." [PMID:11839792] synonym: "dialted ER lumen" EXACT [] is_a: FYPO:0000354 ! abnormal endoplasmic reticulum morphology created_by: vw creation_date: 2023-12-29T18:58:59Z [Term] id: FYPO:0008140 name: dilated nuclear envelope lumen def: "An abnormal nuclear envelope morpbology in the vegetative growth phase of the life cycle in which the nuclear envelope lumen is larger than normal." [PMID:11839792] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology during vegetative growth created_by: vw creation_date: 2023-12-29T19:09:04Z [Term] id: FYPO:0008141 name: decreased RNA level during meiosis II def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal during the second meiotic nuclear division. Total RNA or a specific RNA may be affected." [PMID:16272747] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. synonym: "decreased RNA accumulation during meiosis II" RELATED [] synonym: "decreased RNA level during second meiotic nuclear division" EXACT [] synonym: "decreased transcript level during meiosis II" EXACT [PomBase:vw] synonym: "reduced RNA level during meiosis II" EXACT [] is_a: FYPO:0002959 ! decreased RNA level during meiosis created_by: vw creation_date: 2023-12-29T19:18:34Z [Term] id: FYPO:0008142 name: heme absent from cell def: "A cell phenotype in which the amount heme measured in a cell is too low to detect." [PMID:11248251] is_a: FYPO:0001888 ! substance absent from cell created_by: vw creation_date: 2023-12-29T19:25:56Z [Term] id: FYPO:0008143 name: heme A absent from cell def: "A cell phenotype in which the amount heme A measured in a cell is too low to detect." [PMID:11248251] is_a: FYPO:0008142 ! heme absent from cell created_by: vw creation_date: 2023-12-29T19:25:56Z [Term] id: FYPO:0008144 name: heme O absent from cell def: "A cell phenotype in which the amount heme O measured in a cell is too low to detect." [PMID:11248251] is_a: FYPO:0008142 ! heme absent from cell created_by: vw creation_date: 2023-12-29T19:29:25Z [Term] id: FYPO:0008145 name: decreased level of heme O in cell def: "A cell phenotype in which the amount of heme O measured in a cell is lower than normal." [PMID:11248251] synonym: "decreased heme O level" EXACT [] is_a: FYPO:0000991 ! decreased level of substance in cell created_by: vw creation_date: 2023-12-29T19:32:33Z [Term] id: FYPO:0008146 name: increased ncRNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of non-coding RNA transcribed measured in a cell is higher than normal." [PMID:25989903] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: vw creation_date: 2023-12-29T19:42:09Z [Term] id: FYPO:0008147 name: decreased mRNA splicing, meiotic genes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing of meiosis specific genes is decreased during meiosis." [PMID:27365210] is_a: FYPO:0003244 ! decreased mRNA splicing, via spliceosome, intron-specific created_by: vw creation_date: 2024-01-19T10:08:19Z [Term] id: FYPO:0008148 name: increased CUT RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of transcribed cryptic unstable trancripts (CUTs) measured in a cell is higher than normal." [PMID:25989903] is_a: FYPO:0008149 ! increased non functional ncRNA level created_by: vw creation_date: 2024-01-19T10:33:22Z [Term] id: FYPO:0008149 name: increased non functional ncRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of non-functional non-coding RNA transcribed measured in a cell is higher than normal." [] is_a: FYPO:0008146 ! increased ncRNA level during vegetative growth created_by: vw creation_date: 2024-01-19T10:36:06Z [Term] id: FYPO:0008150 name: increased rDNA intergenic repeat RNA level def: "A cell phenotype in which the amount of RNA derived from rDNA intergenic repeat regions is higher than normal." [] synonym: "increased transcript level at rDNA intergenic region" EXACT [] is_a: FYPO:0008149 ! increased non functional ncRNA level created_by: vw creation_date: 2024-01-19T11:08:32Z [Term] id: FYPO:0008151 name: decreased nucleosome occupancy at centromeric heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in the pericentromeres. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:21211723] synonym: "decreased nucleosome occupancy at centromeric region" RELATED [] is_a: FYPO:0000855 ! abnormal nucleosome positioning in heterochromatin is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: vw creation_date: 2024-01-19T11:21:29Z [Term] id: FYPO:0008152 name: normal CUT RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of transcribed cryptic unstable trancripts (CUTs) measured in a cell is normal (i.e. indistinguishable from wild type). Total CUT RNA or a CUT transcribed from a specific locus may be affected." [] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: vw creation_date: 2024-01-25T07:43:37Z [Term] id: FYPO:0008153 name: abolished protein localization to heterochromatin at silent mating-type cassette during vegetative growth {xref="PMID:16762840"} def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silent mating-type cassette is abolished." [] synonym: "abolished protein localization to mating-type locus heterochromatin during vegetative growth" EXACT [] is_a: FYPO:0001132 ! abolished protein localization to heterochromatin during vegetative growth created_by: vw creation_date: 2024-01-25T08:06:23Z [Term] id: FYPO:0008154 name: normal protein localization to centromeric heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric heterochromatin is normal (i.e. indistinguishable from wild type." [] is_a: FYPO:0005072 ! normal protein localization to centromeric chromatin created_by: vw creation_date: 2024-01-25T08:12:21Z [Term] id: FYPO:0008155 name: abnormal regulatory lncRNA 3'-end processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which regulatory lncRNA 3' end processing is abnormal." [PMID:32415063] is_a: FYPO:0007918 ! abnormal RNA 3'-end processing created_by: vw creation_date: 2024-01-30T16:09:16Z [Term] id: FYPO:0008156 name: RNA absent from cell during cellular response to glucose starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to glucose starvation. Total RNA or a specific RNA may be affected." [PMID:18820678] is_a: FYPO:0003161 ! RNA absent from cell during vegetative growth created_by: vw creation_date: 2024-01-30T16:15:37Z [Term] id: FYPO:0008157 name: abnormal histone deacetylation at the silent mating-type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone deacetylation is abnormal at the silent-mating type locus." [] is_a: FYPO:0000201 ! abnormal histone deacetylation during vegetative growth created_by: vw creation_date: 2024-01-30T16:18:53Z [Term] id: FYPO:0008158 name: increased histone H3-S10 phosphorylation at the silent mating-type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 is increased at the silent mating-type locus." [] {comment="PMID:16246721"} is_a: FYPO:0004080 ! increased histone H3-S10 phosphorylation during vegetative growth created_by: vw creation_date: 2024-01-30T16:21:20Z [Term] id: FYPO:0008159 name: abolished histone H3-S10 phosphorylation at the silent mating-type locus during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation at the silent mating-type locus does not occur. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be abolished." [PMID:16246721] is_a: FYPO:0002592 ! abolished histone phosphorylation during vegetative growth created_by: vw creation_date: 2024-01-30T16:23:13Z [Term] id: FYPO:0008160 name: normal histone H3-K56 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 is normal (i.e. indistinguishable from wild type)." [PMID:18344406] is_a: FYPO:0003221 ! normal histone acetylation during vegetative growth created_by: vw creation_date: 2024-01-30T16:33:35Z [Term] id: FYPO:0008161 name: normal histone H4-K16 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 is normal (i.e. indistinguishable from wild type)." [PMID:18344406] is_a: FYPO:0003221 ! normal histone acetylation during vegetative growth created_by: vw creation_date: 2024-01-30T16:36:56Z [Term] id: FYPO:0008162 name: increased activation of S-phase DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which the incidence of mitotic cell cycle arrest or delay due to regulation by the mitotic S-phase DNA damage checkpoint is greater than in wild type under any specified set of conditions." [PMID:18344406] is_a: FYPO:0000007 ! abnormal S-phase DNA damage checkpoint is_a: FYPO:0001707 ! increased mitotic DNA damage checkpoint activation created_by: vw creation_date: 2024-01-30T16:40:47Z [Term] id: FYPO:0008163 name: increased number of nuclear foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of nuclear foci are increased." [] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: vw creation_date: 2024-03-20T13:41:51Z [Term] id: FYPO:0008164 name: abnormal protein localization to kinetochore during mitotic M phase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal during mitotic M-phase." [] is_a: FYPO:0001268 ! abnormal protein localization to kinetochore during vegetative growth created_by: vw creation_date: 2024-03-20T09:26:50Z [Term] id: FYPO:0008165 name: decreased protein localization to kinetochore during mitotic prometaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during prometaphase of mitosis." [] is_a: FYPO:0005215 ! decreased protein localization to kinetochore during mitotic M phase created_by: vw creation_date: 2024-03-20T09:42:03Z [Term] id: FYPO:0008166 name: abolished protein localization to kinetochore during mitotic prometaphase def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome does not occur during prometaphase of mitosis." [] is_a: FYPO:0008165 ! decreased protein localization to kinetochore during mitotic prometaphase created_by: vw creation_date: 2024-03-20T09:43:57Z [Term] id: FYPO:0008167 name: sensitivite to trolox def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trolox. Cells stop growing (and may die) at a concentration of trolox that allows wild type cells to grow." [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2024-03-20T10:23:11Z [Term] id: FYPO:0008168 name: abolished nuclear foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the nuclear foci are absent." [] is_a: FYPO:0004638 ! abnormal cellular physical quality phenotype created_by: vw creation_date: 2024-03-20T13:43:19Z [Term] id: FYPO:0008169 name: normal actin cable morphology during mitotic interphase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of actin cables are normal during mitotic interphase (i.e. indistinguishable from wild type)." [] is_a: FYPO:0002487 ! normal actin cable morphology created_by: vw creation_date: 2024-03-26T14:43:16Z [Term] id: FYPO:0008170 name: decreased cyclin-dependent protein kinase activity def: "A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is decreased." [] is_a: FYPO:0001382 ! decreased protein kinase activity created_by: vw creation_date: 2024-03-26T14:46:00Z [Term] id: FYPO:0008171 name: increased nuclear pore complex clustering def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear pore complexes are more clustered together than normal." [PMID:35354597] is_a: FYPO:0001321 ! cellular physical quality phenotype during vegetative growth created_by: vw creation_date: 2024-03-26T14:48:45Z [Term] id: FYPO:0008172 name: increased histone H4-K5 acetylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 at the silent mating type cassette occurs to a greater extent than normal." [] is_a: FYPO:0005309 ! increased histone H4-K5 acetylation during vegetative growth created_by: vw creation_date: 2024-03-20T10:47:36Z [Term] id: FYPO:0008173 name: increased histone H4-K8 acetylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 8 of histone H4 in silent mating-type cassettes occurs to a higher extent than normal." [] is_a: FYPO:0005308 ! increased histone H4-K8 acetylation during vegetative growth created_by: vw creation_date: 2024-03-20T10:50:35Z [Term] id: FYPO:0008174 name: increased histone H4-K16 acetylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 16 of histone H4 in silent mating-type cassettes occurs to a higher extent than normal." [] is_a: FYPO:0007632 ! increased histone H4-K16 acetylation during vegetative growth created_by: vw creation_date: 2024-03-20T10:52:51Z [Term] id: FYPO:0008175 name: normal oxygen consumption def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is normal." [] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: vw creation_date: 2024-03-20T11:26:08Z [Term] id: FYPO:0008176 name: increased centromeric inner repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere inner repeat region are present at greater levels than normal." [] comment: This term encompasses both unprocessed RNA transcribed from the centromere inner repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere inner repeat sequences. For levels of RNA transcribed from an exogenous reporter gene placed in the inner repeat region, consider 'decreased chromatin silencing at centromere outer repeat region' (FYPO:0003412). is_a: FYPO:0004982 ! increased centromeric transcript level created_by: vw creation_date: 2024-03-20T11:28:55Z [Term] id: FYPO:0008177 name: normal centromeric RNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNAs transcribed from the centromere measured in a cell is normal (i.e. indistinguishable from wild type)." [] comment: This term encompasses both unprocessed RNA transcribed from the centromere t region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of endogenous RNAs. is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: vw creation_date: 2024-03-20T11:32:16Z [Term] id: FYPO:0008178 name: normal centromeric inner repeat transcript level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere inner repeat region are present at normal levels (i.e. indistinguishable from wild-type)." [] comment: This term encompasses both unprocessed RNA transcribed from the centromere inner repeat region and siRNAs derived by dicer-mediated processing of the primary transcripts. Use this term only for levels of RNA transcribed from endogenous centromere inner repeat sequences. is_a: FYPO:0008177 ! normal centromeric RNA level during vegetative growth created_by: vw creation_date: 2024-03-20T11:34:30Z [Term] id: FYPO:0008179 name: decreased histone H4-K20 monomethylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 is decreased." [PMID:15550243] is_a: FYPO:0004215 ! abnormal histone H4-K20 methylation during vegetative growth created_by: vw creation_date: 2024-03-26T14:54:04Z [Term] id: FYPO:0008180 name: decreased RNA polymerase II CTD binding def: "A molecular function phenotype in which binding by a gene product to the RNA polymerase II CTD domain is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:vw] is_a: FYPO:0001092 ! binding phenotype created_by: vw creation_date: 2024-03-20T11:47:57Z [Term] id: FYPO:0008181 name: decreased RNA polymerase II CTD Ser5-P binding def: "A molecular function phenotype in which binding by a gene product to the RNA polymerase II CTD domain phosphorylated serine 5 is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [PomBase:vw] is_a: FYPO:0008180 ! decreased RNA polymerase II CTD binding created_by: vw creation_date: 2024-03-20T11:51:41Z [Term] id: FYPO:0008182 name: decreased Spt5-CTD binding def: "A molecular function phenotype in which binding by a gene product to the Spt5 CTD domain is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [] is_a: FYPO:0001092 ! binding phenotype created_by: vw creation_date: 2024-03-20T11:55:25Z [Term] id: FYPO:0008183 name: decreased histone H3-S10 phosphorylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3-S10 phosphorylation is decreased." [] is_a: FYPO:0002591 ! abnormal histone phosphorylation during vegetative growth created_by: vw creation_date: 2024-03-20T12:04:24Z [Term] id: FYPO:0008184 name: decreased protein localization to processome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the processome is decreased." [] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: vw creation_date: 2024-03-20T12:10:40Z [Term] id: FYPO:0008185 name: decreased histone H3-K9 trimethylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in the centromere central core occurs to a lower extent than normal." [] is_a: FYPO:0000883 ! decreased histone H3-K9 trimethylation at centromere during vegetative growth created_by: vw creation_date: 2024-03-30T08:45:05Z [Term] id: FYPO:0008186 name: normal histone H3-K9 trimethylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at the centromere central core is normal (i.e. indistinguishable from wild type)." [] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth created_by: vw creation_date: 2024-03-30T08:47:46Z [Term] id: FYPO:0008187 name: abolished histone H4 binding def: "A molecular function phenotype in which occurrence of histone H4 binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:38285941] is_a: FYPO:0007157 ! abnormal histone binding created_by: vw creation_date: 2024-04-09T05:46:05Z [Term] id: FYPO:0008188 name: abolished histone H3-K9 trimethylation at centromere central core during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in the centromere central core is abolished." [] is_a: FYPO:0008368 ! abolished histone H3-K9 trimethylation at centromere during vegetative growth created_by: vw creation_date: 2024-03-30T08:53:43Z [Term] id: FYPO:0008189 name: equational sister chromatid segregation during achiasmatic meiosis I def: "A cellular process phenotype in which sister kinetochores become separated during the first meiotic nuclear division, and sister chromatids subsequently separate to result in equational segregation, only visible in the absence of chiasmata. Equational sister chromatid separation is caused by bi-orientated attachment of sister chromatids." [] is_a: FYPO:0005634 ! sister kinetochore dissociation in meiotic metaphase I with equational sister chromatid segregation in meiosis I created_by: vw creation_date: 2024-03-30T08:56:15Z [Term] id: FYPO:0008190 name: increased protein localization to chromatin at centromere central core during meiotic prophase I def: "A cell phenotype in which the localization of a protein to chromatin at the centromere central core is increased during the meiotic prophase I." [] is_a: FYPO:0003549 ! abnormal protein localization during meiosis created_by: vw creation_date: 2024-03-30T09:13:26Z [Term] id: FYPO:0008191 name: normal replication fork arrest def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at a natural replication barrier is normal (i.e. indistinguishable from wild type)." [] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: vw creation_date: 2024-04-09T05:49:10Z [Term] id: FYPO:0008192 name: increased protein localization to pericentric heterochromatin during meiotic prophase I def: "A cell phenotype in which the localization of a protein to pericentric heterochromatin is increased during prophase of the first meiotic nuclear division." [] is_a: FYPO:0004717 ! abnormal protein localization to heterochromatin during meiosis created_by: vw creation_date: 2024-03-30T09:40:01Z [Term] id: FYPO:0008193 name: normal protein localization to pericentric heterochromatin during meiotic prophase I def: "A cell phenotype in which the localization of a protein to pericentric heterochromatin is normal during prophase of the first meiotic nuclear division." [] is_a: FYPO:0003790 ! normal protein localization during meiosis created_by: vw creation_date: 2024-03-30T09:47:25Z [Term] id: FYPO:0008194 name: sensitive to trolox def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Trolox (antioxidant). Cells stop growing (and may die) at a concentration of Trolox that allows wild type cells to grow." [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2024-03-30T09:50:45Z [Term] id: FYPO:0008195 name: decreased histone H3-K9Me binding def: "A molecular function phenotype in which occurrence of histone H3-KMe binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [] is_a: FYPO:0007158 ! decreased histone H3 binding created_by: vw creation_date: 2024-03-30T09:57:31Z [Term] id: FYPO:0008196 name: increased histone H3-K9Me binding def: "A molecular function phenotype in which occurrence of histone H3-KMe binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene." [] is_a: FYPO:0007835 ! increased histone binding created_by: vw creation_date: 2024-03-30T09:58:36Z [Term] id: FYPO:0008197 name: decreased reticulophagy during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum occurs to a lower extent than normal." [PMID:37553386] is_a: FYPO:0007445 ! abnormal reticulophagy during vegetative growth created_by: vw creation_date: 2024-04-09T05:56:10Z [Term] id: FYPO:0008198 name: decreased protein localization to plasma membrane during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is decreased." [PMID:15572668] is_a: FYPO:0002125 ! abnormal protein localization to plasma membrane during vegetative growth created_by: vw creation_date: 2024-04-15T07:39:55Z [Term] id: FYPO:0008199 name: normal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at the centromere outer repeat is normal (i.e. indistinguishable from wild type)." [] is_a: FYPO:0008070 ! normal histone H3-K9 methylation at centromere during vegetative growth created_by: vw creation_date: 2024-04-15T08:06:39Z [Term] id: FYPO:0008200 name: decreased histone H3-K9 methylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal at the centromere inner repeat." [] {comment="PomBase:vw"} is_a: FYPO:0000872 ! decreased histone H3-K9 methylation during vegetative growth created_by: vw creation_date: 2024-04-15T08:18:10Z [Term] id: FYPO:0008201 name: normal meiotic cell cycle entry def: "A cellular process phenotype in which a cell enters the meiotic cell cycle normally: i.e after conjugation with cellular fusion and karyogamy with nuclear fusion." [] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: vw creation_date: 2024-04-15T08:22:38Z [Term] id: FYPO:0008202 name: equational sister chromatid separation at meiosis I def: "A cellular process phenotype in which meiotic sister chromatid separation occurs in meiosis I due to erroneous merotelic kinetochore attachment." [] is_a: FYPO:0005509 ! abnormal meiotic sister chromatid segregation created_by: vw creation_date: 2024-04-26T17:07:28Z [Term] id: FYPO:0008203 name: normal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at the centromere inner repeat region is normal (i.e. indistinguishable from wild type)." [] {comment="PomBase:vw"} is_a: FYPO:0006683 ! normal histone H3-K9 methylation at centromere inner repeat during vegetative growth created_by: vw creation_date: 2024-04-27T08:08:46Z [Term] id: FYPO:0008204 name: delayed orthogonal actomyosin contractile ring assembly from randomly oriented actomyosin filaments def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell exhibits randomly misoriented actin and myosin II filaments, eventually forming a regular orthogonal actomyosin contractile ring. Although the onset of filaments assembly is not delayed, the cell takes more time complete the formation of an orthogonal actomyosin contractile ring." [] is_a: FYPO:0000729 ! delayed onset of actomyosin contractile ring assembly created_by: vw creation_date: 2024-04-27T08:11:22Z [Term] id: FYPO:0008205 name: increased protein localization to nucleus during hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during hypoxic stress." [PomBase:vw] is_a: FYPO:0001130 ! increased protein localization to nucleus during vegetative growth created_by: vw creation_date: 2024-05-03T11:47:02Z [Term] id: FYPO:0008206 name: abolished protein localization to nucleus during hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during hypoxic stress." [PomBase:vw] is_a: FYPO:0001424 ! abolished protein localization to nucleus during vegetative growth created_by: vw creation_date: 2024-05-03T11:51:41Z [Term] id: FYPO:0008207 name: normal microfilament motor activity def: "A molecular function phenotype in which the observed rate or other property of a microfilament motor activity is normal (i.e. indistinguishable from wild type)." [PomBase:pc] is_a: FYPO:0000706 ! normal molecular function created_by: vw creation_date: 2024-05-03T11:59:25Z [Term] id: FYPO:0008208 name: abolished protein neddylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the neddylation of one or more specific proteins, or of specific protein sites, is abolished." [PomBase:vw] is_a: FYPO:0005819 ! abnormal protein neddylation during vegetative growth created_by: vw creation_date: 2024-05-03T12:03:19Z [Term] id: FYPO:0008209 name: normal histone H3-K14 acetylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is normal at the silent mating-type cassette (i.e. indistinguishable from wild type)." [PomBase:vw] is_a: FYPO:0003224 ! normal histone H3-K14 acetylation during vegetative growth created_by: vw creation_date: 2024-05-03T12:07:01Z [Term] id: FYPO:0008210 name: abolished chromatin binding at promoter region def: "A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more promoter regions does not occur." [PomBase:vw] is_a: FYPO:0001093 ! abolished chromatin binding created_by: vw creation_date: 2024-05-08T13:40:02Z [Term] id: FYPO:0008211 name: decreased antisense RNA level during heat stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell is lower than normal duing heat stress. Antisense RNA is transcribed from the coding, rather than the template, strand of DNA." [PomBase:vw] is_a: FYPO:0004816 ! decreased antisense RNA level created_by: vw creation_date: 2024-05-08T13:47:34Z [Term] id: FYPO:0008212 name: abolished histone H3-K9 methylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur." [PomBase:vw] is_a: FYPO:0002566 ! abolished histone H3-K9 methylation during vegetative growth created_by: vw creation_date: 2024-05-08T13:50:33Z [Term] id: FYPO:0008213 name: increased vegetative cell population growth on lactate carbon source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lactate as the carbon source." [PomBase:vw] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: vw creation_date: 2024-05-08T14:06:36Z [Term] id: FYPO:0008214 name: decreased pre-mRNA level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pre-mRNA measured in a cell during a cellular response to heat is lower than normal. Total pre-mRNA or a specific pre-mRNA may be affected." [PomBase:vw] is_a: FYPO:0002287 ! decreased RNA level during cellular response to heat is_a: FYPO:0002937 ! decreased pre-mRNA level created_by: vw creation_date: 2024-05-08T14:12:11Z [Term] id: FYPO:0008215 name: resistance to Rho GTPase inhibitor O1 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of GTPase inhibitor O1 than normal." [] {comment="PomBase:vw"} is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: vw creation_date: 2024-05-08T14:17:51Z [Term] id: FYPO:0008216 name: abnormal DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA N-glycosylase activity is abnormal." [PomBase:vw] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: vw creation_date: 2024-05-08T14:25:17Z [Term] id: FYPO:0008217 name: increased DNA N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA N-glycosylase activity is increased." [] is_a: FYPO:0008216 ! abnormal DNA N-glycosylase activity created_by: vw creation_date: 2024-05-08T14:33:49Z [Term] id: FYPO:0008218 name: abnormal mitotic S/G2 phase transition def: "A cellular process phenotype in which a cell does not execute a mitotic S/G2 cell cycle phase transition normally." [PMID:10947840] is_a: FYPO:0005275 ! abnormal mitotic cell cycle phase transition created_by: vw creation_date: 2024-05-20T05:34:01Z [Term] id: FYPO:0008219 name: increased histone H3-K56 acetylation in transcribed regions during mitotic G2/M phase def: "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which acetylation of lysine at position 56 of histone H3 in regions of the genome that are actively transcribed occurs to a greater extent than normal." [PMID:27268234] is_a: FYPO:0002370 ! increased histone H3-K56 acetylation in transcribed regions during vegetative growth created_by: vw creation_date: 2024-05-20T05:41:42Z [Term] id: FYPO:0008220 name: increased histone H4-K20 monomethylation in transcribed regions during mitotic G2/M phase def: "A cellular process phenotype observed in the G2/M phase of the mitotic cycle in which monomethylation of lysine at position 20 of histone H4 in regions of the genome that are actively transcribed occurs to a greater extent than normal." [] is_a: FYPO:0004223 ! increased histone H4-K20 monomethylation during vegetative growth created_by: vw creation_date: 2024-05-20T05:48:50Z [Term] id: FYPO:0008221 name: normal histone H3-K56 acetylation during mitotic G2/M phase def: "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which acetylation of lysine at position 56 of histone H3 is normal (i.e. indistinguishable from wild type)." [PMID:27268234] is_a: FYPO:0008160 ! normal histone H3-K56 acetylation during vegetative growth created_by: vw creation_date: 2024-05-20T05:51:36Z [Term] id: FYPO:0008222 name: normal histone H4-K20 monomethylation during mitotic G2/M phase def: "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which monomethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type)." [PMID:27268234] is_a: FYPO:0004220 ! normal histone H4-K20 monomethylation during vegetative growth created_by: vw creation_date: 2024-05-20T05:56:48Z [Term] id: FYPO:0008223 name: normal histone H4-K20 trimethylation during mitotic G2/M phase def: "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which trimethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type)." [PMID:27268234] is_a: FYPO:0004220 ! normal histone H4-K20 monomethylation during vegetative growth created_by: vw creation_date: 2024-05-20T05:58:53Z [Term] id: FYPO:0008224 name: decreased histone H4-K20 trimethylation during mitotic G2/M phase def: "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which trimethylation of lysine at position 20 of histone H4 is decreased." [PMID:27268234] is_a: FYPO:0004224 ! decreased histone H4-K20 trimethylation during vegetative growth created_by: vw creation_date: 2024-05-20T06:01:40Z [Term] id: FYPO:0008225 name: increased cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) measured in a cell (total or free) is higher than normal." [PMID:37949217] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-05-20T06:11:57Z [Term] id: FYPO:0008226 name: increased total cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of phosphate (Pi) measured in a cell is higher than normal." [PMID:37949217] is_a: FYPO:0008225 ! increased cellular phosphate (Pi) level created_by: vw creation_date: 2024-05-20T06:19:32Z [Term] id: FYPO:0008227 name: increased free cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of free phosphate (Pi) measured in a cell is higher than normal." [PMID:37949217] is_a: FYPO:0008225 ! increased cellular phosphate (Pi) level created_by: vw creation_date: 2024-05-20T06:22:59Z [Term] id: FYPO:0008228 name: abnormal phosphate export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of phosphate ions (Pi) out of a cell is abnormal." [PMID:37949217] is_a: FYPO:0005973 ! abnormal transport during vegetative growth created_by: vw creation_date: 2024-05-20T06:31:25Z [Term] id: FYPO:0008229 name: sensitive to phosphate (Pi) def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phosphate (Pi). Cells stop growing (and may die) at a concentration of phosphate that allows wild type cells to grow." [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2024-05-20T06:42:53Z [Term] id: FYPO:0008230 name: normal replication fork arrest at MPS1 barrier def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the MPS1 barrier located in the mating-type region is normal (i.e. indistinguishable from wild-type)." [] {comment="PomBase:vw"} is_a: FYPO:0008191 ! normal replication fork arrest created_by: vw creation_date: 2024-06-17T11:26:44Z [Term] id: FYPO:0008231 name: increased lactate dehydrogenase activity def: "A molecular function phenotype in which the observed rate of lactate dehydrogenase activity is increased." [PMID:37787465] is_a: FYPO:0000662 ! increased catalytic activity created_by: vw creation_date: 2024-05-20T06:54:47Z [Term] id: FYPO:0008232 name: microtubule bundles present in increased numbers during mitotic M phase def: "A physical cellular phenotype in which cells contain more microtubule bundles than normal during mitotic M-phase." [PomBase:vw] is_a: FYPO:0002401 ! microtubule bundles present in increased numbers created_by: vw creation_date: 2024-06-17T11:30:48Z [Term] id: FYPO:0008233 name: microtubule bundles present in normal numbers def: "A physical cellular phenotype in which cells contain a normal number of microtubule bundles." [] {comment="PomBase:vw"} is_a: FYPO:0000899 ! normal microtubule cytoskeleton organization during vegetative growth created_by: vw creation_date: 2024-06-17T11:41:37Z [Term] id: FYPO:0008234 name: normal protein localization to cytoplasmic puncta def: "A cell phenotype in which a protein is localized to discrete regions in the cytoplasm, visible as foci or dots by microscopy, to the same extent as observed in normal (wild type) cells." [PomBase:vw] is_a: FYPO:0001788 ! normal protein localization to cytoplasm created_by: vw creation_date: 2024-06-17T11:44:21Z [Term] id: FYPO:0008235 name: abolished nuclear RNA-directed RNA polymerase complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of the nuclear RNA-directed RNA polymerase complex is abolished." [] {comment="PomBase:vw"} is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: vw creation_date: 2024-06-17T11:49:20Z [Term] id: FYPO:0008236 name: normal siRNA loading onto RITS complex def: "An RNA localization phenotype where the loading of siRNAs onto the RITs complex is normal (i.e. indistinguishable from wild type)." [PomBase:vw] is_a: FYPO:0003059 ! normal RNA localization to chromatin created_by: vw creation_date: 2024-06-17T11:59:07Z [Term] id: FYPO:0008237 name: normal glycerophospholipid level during vegetative growth def: "A cell phenotype in which the amount of glycerophospholipid measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle." [] {comment="PomBase:vw"} is_a: FYPO:0001076 ! normal level of substance in cell created_by: vw creation_date: 2024-06-17T12:03:23Z [Term] id: FYPO:0008238 name: increased total cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of polyphosphate measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0007816 ! increased cellular polyphosphate level created_by: vw creation_date: 2024-06-17T12:16:18Z [Term] id: FYPO:0008239 name: increased free cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of free polyphosphate measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0007816 ! increased cellular polyphosphate level created_by: vw creation_date: 2024-06-17T12:17:20Z [Term] id: FYPO:0008240 name: decreased total cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of polyphosphate measured in a cell is lower than normal." [PomBase:vw] is_a: FYPO:0008024 ! decreased cellular polyphosphate level created_by: vw creation_date: 2024-06-17T12:19:59Z [Term] id: FYPO:0008241 name: decreased free cellular polyphosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of free polyphosphate measured in a cell is lower than normal." [PomBase:vw] is_a: FYPO:0008024 ! decreased cellular polyphosphate level created_by: vw creation_date: 2024-06-17T12:22:45Z [Term] id: FYPO:0008242 name: abnormal nuclear morphology during meiotic cell cycle def: "A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal during the meiotic cell cycle." [PomBase:vw] is_a: FYPO:0002256 ! abnormal nuclear morphology created_by: vw creation_date: 2024-06-17T12:42:06Z [Term] id: FYPO:0008243 name: abnormal nuclear morphology during sporulation def: "A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal during sporulation." [PomBase:vw] is_a: FYPO:0008242 ! abnormal nuclear morphology during meiotic cell cycle created_by: vw creation_date: 2024-06-17T12:46:19Z [Term] id: FYPO:0008244 name: abolished protein localization to prospore wall def: "A cell phenotype in which a protein does not localize to, and is therefore absent from the prospore wall." [PomBase:vw] is_a: FYPO:0005208 ! abolished protein localization during meiotic cell cycle created_by: vw creation_date: 2024-06-17T12:50:50Z [Term] id: FYPO:0008245 name: normal protein localization to chromatin at gene promoter region def: "A cell phenotype in which the localization of a protein to chromatin at one or more specific promoter elements is normal (i.e. indistinguishable from wild type) during vegetative growth." [PMID:27538348] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: vw creation_date: 2024-07-04T09:30:07Z [Term] id: FYPO:0008246 name: normal cenH-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from cenH measured in a cell is normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs." [PomBase:pc] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: vw creation_date: 2024-07-04T10:22:47Z [Term] id: FYPO:0008247 name: decreased subtelomeric heterochromatin RNA level def: "A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin regions is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PMID:25356590, PomBase:pc] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: vw creation_date: 2024-07-04T10:28:51Z [Term] id: FYPO:0008248 name: decreased LTR-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from long terminal repeat elements (LTRs) measured in a cell is lower than normal." [PomBase:pc] {comment="PMID:25356590"} is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: vw creation_date: 2024-07-04T10:31:20Z [Term] id: FYPO:0008249 name: decreased protein localization to chromatin at protein coding gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more protein-coding genes is decreased." [PMID:25356590, PomBase:pc] is_a: FYPO:0002909 ! decreased protein localization to chromatin during vegetative growth created_by: vw creation_date: 2024-07-04T10:46:57Z [Term] id: FYPO:0008250 name: normal protein localization to chromatin at protein coding gene def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more protein-coding genes is normal (i.e. indistinguishable from wild type)." [PMID:25356590, PomBase:pc] is_a: FYPO:0001509 ! normal protein localization to chromatin during vegetative growth created_by: vw creation_date: 2024-07-04T10:57:44Z [Term] id: FYPO:0008251 name: decreased silent mating-type cassette transcript-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from cenH measured in a cell is lower than normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs." [PMID:25356590, PomBase:pc] synonym: "decreased cenH-derived RNA level" EXACT [] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: vw creation_date: 2024-07-04T11:13:18Z [Term] id: FYPO:0008252 name: normal LTR-derived RNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from long terminal repeat elements (LTRs) measured in a cell is normal (i.e. indistinguishable from wild type)." [PMID:25356590] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: vw creation_date: 2024-07-04T11:16:06Z [Term] id: FYPO:0008253 name: normal telomere repeat region derived RNA level def: "A cell phenotype in which the amount of telomere repeat derived RNA measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle." [PMID:27183912] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: vw creation_date: 2024-07-04T11:56:39Z [Term] id: FYPO:0008254 name: increased histone H3-K4 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a greater extent than normal in regions containing protein-coding genes." [PMID:25356590] is_a: FYPO:0004238 ! increased histone H3-K4 acetylation during vegetative growth created_by: vw creation_date: 2024-07-04T12:06:21Z [Term] id: FYPO:0008255 name: decreased histone H3-K4 acetylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a lower extent than normal in regions containing protein-coding genes." [PMID:25356590] is_a: FYPO:0004239 ! decreased histone H3-K4 acetylation during vegetative growth created_by: vw creation_date: 2024-07-04T12:08:52Z [Term] id: FYPO:0008256 name: decreased histone H3-K4 acetylation at LTR during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a lower extent than normal at long terminal repeat (LTR) regions." [PMID:25356590] is_a: FYPO:0004239 ! decreased histone H3-K4 acetylation during vegetative growth created_by: vw creation_date: 2024-07-04T12:13:44Z [Term] id: FYPO:0008257 name: increased histone H3-K4 acetylation at LTR during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a greater extent than normal at long terminal repeat (LTR) regions." [PMID:25356590] is_a: FYPO:0004238 ! increased histone H3-K4 acetylation during vegetative growth created_by: vw creation_date: 2024-07-04T12:30:40Z [Term] id: FYPO:0008258 name: decreased protein localization to cell surface def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is decreased. The cell surface refers to the external part of the cell wall and/or plasma membrane." [] is_a: FYPO:0002814 ! abnormal protein localization to cell surface created_by: vw creation_date: 2024-07-04T12:54:09Z [Term] id: FYPO:0008259 name: decreased protein localization to cell surface with increased localization to endosomal structures def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is decreased, and the localizatiion to the endosomal structure is increased. The cell surface refers to the external part of the cell wall and/or plasma membrane." [PMID:22848669] is_a: FYPO:0008258 ! decreased protein localization to cell surface created_by: vw creation_date: 2024-07-04T12:56:18Z [Term] id: FYPO:0008260 name: decreased protein localization to cell surface, protein mislocalized to endoplasmic reticulum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is decreased, and the localizatiion to the endoplasmic reticulum is increased. The cell surface refers to the external part of the cell wall and/or plasma membrane." [PMID:22848669] is_a: FYPO:0008258 ! decreased protein localization to cell surface created_by: vw creation_date: 2024-07-04T12:56:43Z [Term] id: FYPO:0008261 name: decreased cellular mannosylinositol phosphorylceramide level def: "A cell phenotype in which the amount of annosylinositol phosphorylceramide measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle." [PMID:20388730] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-07-04T13:03:22Z [Term] id: FYPO:0008262 name: mannosylinositol phosphorylceramide absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mannosylinositol phosphorylceramide measured in a cell is too low to detect." [PMID:20388730] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0008261 ! decreased cellular mannosylinositol phosphorylceramide level created_by: vw creation_date: 2024-07-04T13:06:10Z [Term] id: FYPO:0008263 name: abolished protein kinase activity in response to osmotic stress def: "A molecular function phenotype in which a protein kinase activity is absent during a cellular response to osmotic stress." [PMID:24498240] is_a: FYPO:0001384 ! abolished protein kinase activity created_by: vw creation_date: 2024-07-04T13:24:16Z [Term] id: FYPO:0008264 name: abolished protein kinase activity in response to oxidative stress def: "A molecular function phenotype in which a protein kinase activity is absent during a cellular response to oxidative stress." [PMID:24498240] is_a: FYPO:0001384 ! abolished protein kinase activity created_by: vw creation_date: 2024-07-04T13:24:34Z [Term] id: FYPO:0008265 name: normal chromatin silencing at rDNA def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing in at rDNA is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin." [] is_a: FYPO:0002335 ! normal chromatin silencing created_by: vw creation_date: 2024-07-04T13:31:34Z [Term] id: FYPO:0008266 name: normal cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) in the cell is normal (i.e. indistinguishable from wild type)." [PMID:37949217] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: vw creation_date: 2024-07-04T13:35:05Z [Term] id: FYPO:0008267 name: normal total cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of phosphate (Pi) in the cell is normal (i.e. indistinguishable from wild type)." [] xref: PMID:37949217 is_a: FYPO:0008266 ! normal cellular phosphate (Pi) level created_by: vw creation_date: 2024-07-04T13:36:58Z [Term] id: FYPO:0008268 name: decreased cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) measured in the cell is lower than normal." [PMID:37949217] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-07-04T13:40:48Z [Term] id: FYPO:0008269 name: decreased total cellular phosphate (Pi) level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of phosphate (Pi) measured in the cell is lower than normal." [PMID:37949217] is_a: FYPO:0008268 ! decreased cellular phosphate (Pi) level created_by: vw creation_date: 2024-07-04T13:41:40Z [Term] id: FYPO:0008270 name: increased H3-K56 acetylation during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 occurs to a higher extent than normal." [PMID:20299449] is_a: FYPO:0000332 ! increased histone acetylation during vegetative growth created_by: vw creation_date: 2024-07-22T11:42:36Z [Term] id: FYPO:0008271 name: normal histone binding def: "A molecular function phenotype in which the binding of a protein to a histone is normal (i.e. indistinguishable from wild type)." [PomBase:vw] is_a: FYPO:0000703 ! normal protein-protein interaction created_by: vw creation_date: 2024-07-22T11:51:17Z [Term] id: FYPO:0008272 name: normal histone H3 binding def: "A molecular function phenotype in which occurrence of histone H3 binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). The affected gene product may be encoded by the mutated gene, or by a different gene." [] {comment="PomBase:pc"} is_a: FYPO:0008271 ! normal histone binding created_by: vw creation_date: 2024-07-22T11:54:29Z [Term] id: FYPO:0008273 name: normal histone H4 binding def: "A molecular function phenotype in which occurrence of histone H4 binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). The affected gene product may be encoded by the mutated gene, or by a different gene." [] {comment="PomBase:pc"} is_a: FYPO:0008271 ! normal histone binding created_by: vw creation_date: 2024-07-22T11:55:31Z [Term] id: FYPO:0008274 name: decreased glutamate biosynthesis def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which glutamate biosynthesis is abnormal." [PomBase:vw] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: vw creation_date: 2024-07-22T14:07:46Z [Term] id: FYPO:0008275 name: normal polyphosphatase activity def: "A molecular function phenotype in which the observed rate of a polyphosphatase activity is normal (i.e. indistinguishable from wild type)." [] is_a: FYPO:0000660 ! normal catalytic activity created_by: vw creation_date: 2024-07-29T11:30:26Z [Term] id: FYPO:0008276 name: abolished polyphosphatase activity def: "A molecular function phenotype in which a polyphosphatase activity is absent." [PomBase:vw] is_a: FYPO:0000664 ! abolished catalytic activity created_by: vw creation_date: 2024-07-29T11:34:21Z [Term] id: FYPO:0008277 name: increased cellular 1,5-IP8 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate (1,5-IP8) measured in a cell is higher than normal." [PomBase:pc] is_a: FYPO:0006950 ! increased cellular myo-inositol level created_by: vw creation_date: 2024-07-29T11:50:35Z [Term] id: FYPO:0008278 name: increased cellular 5-IP7 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate (5-IP7) is higher than normal." [PomBase:pc] is_a: FYPO:0006950 ! increased cellular myo-inositol level created_by: vw creation_date: 2024-07-29T12:01:32Z [Term] id: FYPO:0008279 name: increased cellular 1-IP7 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate (1-IP7) is higher than normal." [PomBase:pc] is_a: FYPO:0006950 ! increased cellular myo-inositol level created_by: vw creation_date: 2024-07-29T12:28:01Z [Term] id: FYPO:0008280 name: decreased cellular myo-inositol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of myo-inositol measured in a cell is lower than normal." [PomBase:vw] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-07-29T12:42:06Z [Term] id: FYPO:0008281 name: decreased cellular 1,5-IP8 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate (1,5-IP8) measured in a cell is lower than normal." [PomBase:pc] is_a: FYPO:0008280 ! decreased cellular myo-inositol level created_by: vw creation_date: 2024-07-29T12:59:07Z [Term] id: FYPO:0008282 name: decreased cellular 5-IP7 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate (5-IP7) is lower than normal." [PomBase:pc] is_a: FYPO:0008280 ! decreased cellular myo-inositol level created_by: vw creation_date: 2024-07-29T13:00:49Z [Term] id: FYPO:0008283 name: decreased cellular 1-IP7 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate (1-IP7) is lower than normal." [PomBase:pc] is_a: FYPO:0008280 ! decreased cellular myo-inositol level created_by: vw creation_date: 2024-07-29T13:02:46Z [Term] id: FYPO:0008284 name: normal cellular myo-inositol level def: "A cell phenotype in which the amount of myo-inositol in a cell is normal when the cell is in the vegetative growth phase of the life cycle." [] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: vw creation_date: 2024-07-29T13:05:36Z [Term] id: FYPO:0008285 name: normal cellular 5-IP7 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate (5-IP7) is normal (i.e. indistinguishable from wild type)." [PomBase:pc] is_a: FYPO:0008284 ! normal cellular myo-inositol level created_by: vw creation_date: 2024-07-29T13:10:24Z [Term] id: FYPO:0008286 name: normal cellular 1-IP7 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate (1-IP7) is normal (i.e. indistinguishable from wild type)." [] {comment="PomBase:pc"} is_a: FYPO:0008284 ! normal cellular myo-inositol level created_by: vw creation_date: 2024-07-29T13:14:13Z [Term] id: FYPO:0008287 name: sensitive to 1-chloro-2,4-dinitrobenzene def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1-chloro-2,4-dinitrobenzene (CDNB). Cells stop growing (and may die) at a concentration of 1-chloro-2,4-dinitrobenzene that allows wild type cells to grow." [PomBase:pc] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2024-09-02T10:33:42Z [Term] id: FYPO:0008288 name: increased cellular ceramide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a ceramide measured in a cell higher than normal." [PomBase:pc] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-09-02T10:41:06Z [Term] id: FYPO:0008289 name: abnormal guanyl-nucleotide exchange factor activity def: "A molecular function phenotype in which a guanyl-nucleotide exchange factor activity is abnormal." [PomBase:vw] synonym: "abnormal GEF activity" EXACT [] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: vw creation_date: 2024-09-02T10:48:48Z [Term] id: FYPO:0008290 name: abolished guanyl-nucleotide exchange factor activity def: "A molecular function phenotype in which a guanyl-nucleotide exchange factor activity is absent." [PomBase:vw] synonym: "abolished GEF activity" EXACT [] is_a: FYPO:0008289 ! abnormal guanyl-nucleotide exchange factor activity created_by: vw creation_date: 2024-09-02T10:51:58Z [Term] id: FYPO:0008291 name: increased cellular mtDNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial DNA present in the cell is higher than normal." [PomBase:vw] synonym: "increased mitochondrial DNA content" EXACT [PomBase:vw] synonym: "increased mitochondrial DNA copy number" RELATED [PomBase:vw] synonym: "increased mitochondrial genome copy number" RELATED [PomBase:vw] synonym: "increased mtDNA level" EXACT [PomBase:vw] is_a: FYPO:0000158 ! DNA content increased during vegetative growth created_by: vw creation_date: 2024-09-30T11:28:00Z [Term] id: FYPO:0008292 name: increased phosphatidylinositol-4,5-bisphosphate level in the cell division site plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the cell division site plasma membrane is higher than normal." [] synonym: "increased cell sivision site plasma membrane PI(4,5)P2 level" EXACT [] is_a: FYPO:0006626 ! increased phosphatidylinositol-4,5-bisphosphate level in plasma membrane created_by: vw creation_date: 2024-09-30T11:44:01Z [Term] id: FYPO:0008293 name: protein mislocalized to cell division site def: "A cell phenotype in which a protein that is not normally found in the cell division site is observed there." [PomBase:vw] is_a: FYPO:0003452 ! mislocalized protein created_by: vw creation_date: 2024-09-30T11:51:06Z [Term] id: FYPO:0008294 name: normal plasma membrane-ER tethering def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Endoplasmic Reticulum tethering to the plasma membrane is normal. Normal ER to plasma membrane tethering results in correct localization of the ER." [PomBase:vw] is_a: FYPO:0007915 ! normal endoplasmic reticulum localization created_by: vw creation_date: 2024-09-30T12:02:17Z [Term] id: FYPO:0008295 name: sensitive to guanazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to guanozole. Cells stop growing (and may die) at a concentration of guanozole that allows wild type cells to grow." [PomBase:pc] synonym: "fission_yeast_phenotype" RELATED [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2024-09-30T13:24:06Z [Term] id: FYPO:0008296 name: increased cellular 24-methylene lanosterol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 24-methylene lanosterol measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-09-30T13:55:04Z [Term] id: FYPO:0008297 name: increased cellular ergosta-5,7,24(28)-trienol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosta- 5,7,24(28)-trienol measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-09-30T13:57:24Z [Term] id: FYPO:0008298 name: increased ergosta-5,7-dienol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosta-5,7-dienol measured in a cell is higher than normal." [] comment: ergosta-5,7-dienol level is not a normal pathway intermediate, but forms when Erg5 is inhibited. is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-09-30T14:00:34Z [Term] id: FYPO:0008299 name: decreased rate of protein exchange at plasma membrane def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange between the plasma membrane and the cytosol is decreased." [PomBase:pc] is_a: FYPO:0005544 ! abnormal protein localization to plasma membrane at cell division site during vegetative growth created_by: vw creation_date: 2024-10-07T09:51:54Z [Term] id: FYPO:0008300 name: abnormal punctate nuclear protein localization during meiotic prophase I def: "A cell phenotype observed during prophase of the first division of the meiotic cell cycle in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized." [PomBase:pc] is_a: FYPO:0003549 ! abnormal protein localization during meiosis created_by: vw creation_date: 2024-10-07T10:00:27Z [Term] id: FYPO:0008301 name: decreased punctate nuclear protein localization during meiotic prophase I def: "A cell phenotype observed during prophase of the first division of the meiotic cell cycle in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that fewer dots are observed than in normal (wild type) cells." [PomBase:pc] is_a: FYPO:0008300 ! abnormal punctate nuclear protein localization during meiotic prophase I created_by: vw creation_date: 2024-10-07T10:02:04Z [Term] id: FYPO:0008302 name: abolished punctate nuclear protein localization during meiotic prophase I def: "A cell phenotype observed during prophase of the first division of the meiotic cell cycle in which the localization of a protein to discrete regions in the nucleus, visible as foci or dots by microscopy, is abolished." [PomBase:pc] is_a: FYPO:0008300 ! abnormal punctate nuclear protein localization during meiotic prophase I created_by: vw creation_date: 2024-10-07T10:03:21Z [Term] id: FYPO:0008303 name: normal number of Rad51 foci during meiotic prophase I def: "A cell phenotype observed during prophase of the first division of the meiotic cell cycle in which the number of sites at which the protein Rad51 accumulates is normal (i.e. indistinguishable from wild type)." [PomBase:pc] is_a: FYPO:0003790 ! normal protein localization during meiosis created_by: vw creation_date: 2024-10-07T10:06:50Z [Term] id: FYPO:0008304 name: abolished protein localization to nucleus during meiosis def: "A cell phenotype in which the localization of a protein to the nucleus during one or both meiotic nuclear divisions is abolished." [PomBase:pc] is_a: FYPO:0002957 ! abnormal protein localization to nucleus during meiosis created_by: vw creation_date: 2024-10-07T10:12:16Z [Term] id: FYPO:0008305 name: increased inter-sister chromatid meiotic recombination def: "A cellular process phenotype in which the occurrence of meiotic recombination between alleles on different sister chromatids (inter-sister recombination) is increased." [PomBase:pc] is_a: FYPO:0000487 ! increased meiotic recombination created_by: vw creation_date: 2024-10-07T10:17:50Z [Term] id: FYPO:0008306 name: increased mitotic DNA replication initiation from late origin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the frequency of DNA replication initiation is higher than normal at layte origins." [] is_a: FYPO:0001344 ! abnormal mitotic DNA replication initiation created_by: vw creation_date: 2024-10-07T10:25:43Z [Term] id: FYPO:0008307 name: decreased cell diameter at division def: "A cell phenotype in which a cell divides with a smaller diameter than normal (i.e. compared to wild-type cells under the same conditions)." [PomBase:pc] is_a: FYPO:0001877 ! viable thin vegetative cell created_by: vw creation_date: 2024-10-07T10:31:53Z [Term] id: FYPO:0008308 name: increased cell volume at division def: "A cell phenotype in which a cell divides with a greater volume than normal (i.e. compared to wild-type cells under the same conditions)." [PomBase:pc] is_a: FYPO:0002377 ! viable swollen vegetative cell created_by: vw creation_date: 2024-10-07T10:39:11Z [Term] id: FYPO:0008309 name: increased cell surface area at division def: "A cell phenotype in which a cell divides with a greater surface area than normal (i.e. compared to wild-type cells under the same conditions)." [PomBase:pc] is_a: FYPO:0002377 ! viable swollen vegetative cell created_by: vw creation_date: 2024-10-07T10:42:26Z [Term] id: FYPO:0008310 name: unstable meiotic telomere clustering def: "A cell phenotype in which meiotic telomere clustering is unstable, leading to transient unclustering of telomeres." [PMID:34067465] is_a: FYPO:0000172 ! abnormal meiotic telomere clustering created_by: vw creation_date: 2024-10-14T09:03:38Z [Term] id: FYPO:0008311 name: normal protein localization to meiotic spindle pole body during prophase I def: "A cell phenotype in which the localization of a protein to the meiotic spindle pole body during prophase of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type)." [PomBase:pc] is_a: FYPO:0004764 ! normal protein localization to meiotic spindle pole body during meiosis I created_by: vw creation_date: 2024-10-14T09:17:47Z [Term] id: FYPO:0008312 name: increased split sister centromeres in early mitosis def: "A cellular process phenotype in which mitotic sister chromatid cohesion is increased at the centromeres in early mitosis. Contromeric cohesion is usually protected until the metaphase anaphase transition." [PomBase:vw] synonym: "increased sister kinetochore dissociation at centromeres" EXACT [] synonym: "increased split sister centromeres in mitosis" BROAD [] is_a: FYPO:0006521 ! abnormal mitotic sister chromatid cohesion created_by: vw creation_date: 2024-11-12T13:58:37Z [Term] id: FYPO:0008313 name: normal meiotic spindle pole body insertion into nuclear envelope in meiosis I def: "A cellular process phenotype in which insertion of the spindle pole body into the nuclear envelope during the first meiotic nuclear division is normal." [PomBase:vw] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: vw creation_date: 2024-10-14T09:43:14Z [Term] id: FYPO:0008314 name: normal initial meiotic spindle pole body separation in meiosis I def: "A cellular process phenotype in which the initial release of duplicated spindle pole bodies that occurs as part of the first meiotic nuclear division, is normal (i.e. indistinguishable from wild type)." [] is_a: FYPO:0007078 ! normal meiotic cell cycle process created_by: vw creation_date: 2024-10-14T09:45:00Z [Term] id: FYPO:0008315 name: normal mitochondrial ribosome assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial ribosome assembly is normal (i.e. indistinguishable from wild type)." [PomBase:vw] is_a: FYPO:0001215 ! normal protein complex assembly during vegetative growth created_by: vw creation_date: 2024-10-25T09:32:56Z [Term] id: FYPO:0008316 name: abnormal mitochondrial translation initiation complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial ribosome complex assembly is abnormal." [] {def="PomBase:vw"} is_a: FYPO:0000447 ! abnormal protein-containing complex assembly created_by: vw creation_date: 2024-10-25T09:39:44Z [Term] id: FYPO:0008317 name: loss of viability in stationary phase upon sulfur starvation def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase, when cells the population are subject to sulfur starvation." [PomBase:vw] is_a: FYPO:0000245 ! loss of viability in stationary phase is_a: FYPO:0007088 ! loss of viability upon sulfur starvation created_by: vw creation_date: 2024-10-25T09:49:56Z [Term] id: FYPO:0008318 name: normal RNA level during sulfur starvation def: "A cell phenotype in which the amount of RNA measured in a cell that is subject to sulfur starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [] is_a: FYPO:0000840 ! normal RNA level created_by: vw creation_date: 2024-10-25T09:54:09Z [Term] id: FYPO:0008319 name: normal macroautophagy during sulfur starvation def: "A cellular process phenotype in which macroautophagy is normal (i.e. indistinguishable from wild type) when the cell is subject to sulfur starvation. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm." [] is_a: FYPO:0000385 ! normal macroautophagy created_by: vw creation_date: 2024-10-25T09:58:09Z [Term] id: FYPO:0008320 name: abnormal cell morphology during sulphur deprivation def: "A cell phenotype in which cell morphology (i.e. the size, shape, or structure of the cell) is altered when the cell is subject to sulfur deprivation." [] {comment="PomBase:vw"} is_a: FYPO:0000005 ! abnormal cell morphology created_by: vw creation_date: 2024-10-25T10:01:27Z [Term] id: FYPO:0008321 name: abolished sporulation during nitrogen starvation def: "A cellular process phenotype in which ascospore formation does not occur when cells are subject to nitrogen starvation" [] {comment="PomBase:vw"} is_a: FYPO:0000583 ! abolished sporulation created_by: vw creation_date: 2024-10-25T10:03:04Z [Term] id: FYPO:0008322 name: decreased histone H3-K9 acetylation at promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 9 of histone H3 at one or more promoter regions occurs to a lower extent than normal." [PomBase:pc] is_a: FYPO:0001442 ! decreased histone H3-K9 acetylation during vegetative growth created_by: vw creation_date: 2024-11-12T14:10:02Z [Term] id: FYPO:0008323 name: decreased histone H3-K14 acetylation at promoter during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 14 of histone H3 at one or more promoter regions occurs to a lower extent than normal." [PomBase:pc] is_a: FYPO:0000788 ! abnormal histone H3-K14 acetylation during vegetative growth created_by: vw creation_date: 2024-11-12T14:15:48Z [Term] id: FYPO:0008324 name: decreased cytosolic ribosome content def: "A cellular phenotype observed in the vegetative growth phase of the life cycle in which the total cytosolic ribosome content (monosomes + polysomes) in a cell is lower than normal." [PMID:39358553, PomBase:pc] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: vw creation_date: 2024-11-12T14:22:36Z [Term] id: FYPO:0008325 name: increased cytosolic ribosome content def: "A cellular phenotype observed in the vegetative growth phase of the life cycle in which the total cytosolic ribosome content (monosomes + polysomes) in a cell is higher than normal." [PMID:39358553, PomBase:pc] is_a: FYPO:0003684 ! altered level of macromolecular complex during vegetative growth created_by: vw creation_date: 2024-11-12T14:22:36Z creation_date: 2024-11-12T14:26:01Z [Term] id: FYPO:0008326 name: increased histone H3-K9 trimethylation at protein coding gene during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a greater extent than normal." [PomBase:pc] {comment="PMID:39094565"} is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation during vegetative growth created_by: vw creation_date: 2024-11-12T14:50:27Z [Term] id: FYPO:0008327 name: increased histone H3-K9 trimethylation at heterochromatin island during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a greater extent than normal." [] {comment="PMID:39094565", comment="PomBase:pc"} is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation during vegetative growth created_by: vw creation_date: 2024-11-12T14:54:16Z [Term] id: FYPO:0008328 name: decreased phosphatidylinositol binding def: "A molecular function phenotype in which occurrence of phosphatidylinositol binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene." [] {comment="PomBase:vw"} comment: This term can mean that the mutated gene product itself binds one or more phospholipids less than wild type, or that a mutation in one gene decreases phospholipid binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0005307 ! decreased phospholipid binding created_by: vw creation_date: 2024-11-12T14:58:44Z [Term] id: FYPO:0008329 name: phosphatidylserine absent from plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in the plasma membrane is too low to detect." [] {comment="PomBase:vw"} is_a: FYPO:0001289 ! decreased phospholipid level created_by: vw creation_date: 2024-11-12T15:07:47Z [Term] id: FYPO:0008330 name: increased phosphatidylinositol-4-phosphate level in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the plasma membrane is higher than normal." [] {comment="PomBase:vw"} is_a: FYPO:0001288 ! increased phospholipid level is_a: FYPO:0008331 ! altered level of substance in plasma membrane created_by: vw creation_date: 2024-11-12T15:38:33Z [Term] id: FYPO:0008331 name: altered level of substance in plasma membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the plasma membrane is higher than normal." [PomBase:vw] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: vw creation_date: 2024-11-12T15:50:09Z [Term] id: FYPO:0008332 name: decreased mRNA poly(A) tail uridylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the poly(A) tails of mRNA molecules occurs to a lower extent than normal." [PMID:39333464] is_a: FYPO:0000372 ! decreased RNA modification created_by: vw creation_date: 2024-11-28T11:52:11Z [Term] id: FYPO:0008333 name: normal ribosome hibernation during glucose starvation def: "A cellular process phenotype in which ribosome hibernation is normal (i.e. indistinguishable from wild type) during glucose starvation." [PMID:39379376] is_a: FYPO:0000627 ! normal cellular process created_by: vw creation_date: 2024-11-12T16:14:12Z [Term] id: FYPO:0008334 name: abolished ribosome to mitochondrion tethering def: "A phenotype in which a ribosome tethering to the ribosome function is abolished." [] is_a: FYPO:0000707 ! abnormal molecular function created_by: vw creation_date: 2024-11-12T16:21:32Z [Term] id: FYPO:0008335 name: increased mRNA poly(A) tail uridylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the poly(A) tails of mRNA molecules occurs to a higher extent than normal." [PMID:39333464] is_a: FYPO:0000374 ! increased RNA modification created_by: vw creation_date: 2024-11-28T11:53:32Z [Term] id: FYPO:0008336 name: abolished mRNA poly(A) tail uridylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the poly(A) tails of mRNA molecules is abolished." [PMID:39333464] is_a: FYPO:0000371 ! abolished RNA modification created_by: vw creation_date: 2024-11-28T11:52:11Z [Term] id: FYPO:0008337 name: decreased 3' end uridylation of non-polyadenylated RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the 3' ends of non-polyadenylated RNA molecules occurs to a lower extent than normal." [PMID:39333464] is_a: FYPO:0000372 ! decreased RNA modification created_by: vw creation_date: 2024-11-28T11:52:11Z [Term] id: FYPO:0008338 name: increased 3' end uridylation of non-polyadenylated RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the 3' ends of non-polyadenylated RNA molecules occurs to a higher extent than normal." [PMID:39333464] is_a: FYPO:0000374 ! increased RNA modification created_by: vw creation_date: 2024-11-28T11:52:11Z [Term] id: FYPO:0008339 name: abolished 3' end uridylation of non-polyadenylated RNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the 3' ends of non-polyadenylated RNA molecules is abolished." [PMID:39333464] is_a: FYPO:0000371 ! abolished RNA modification created_by: vw creation_date: 2024-11-28T12:00:12Z [Term] id: FYPO:0008340 name: abolished ubiquitin ligase activator activity def: "A molecular function phenotype in which the activation of a ubiquitin ligase activator does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene." [PMID:22437499] is_a: FYPO:0000707 ! abnormal molecular function created_by: vw creation_date: 2024-12-05T10:48:31Z [Term] id: FYPO:0008341 name: decreased nucleosome occupancy in gene body def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal within the body of a gene. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PomBase:vw] is_a: FYPO:0004491 ! decreased nucleosome occupancy created_by: vw creation_date: 2024-12-31T13:38:07Z [Term] id: FYPO:0008342 name: decreased pre-tRNA or mature level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transfer RNAs measured in a cell is lower than normal. Total tRNA or a specific tRNA may be affected." [] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth is_a: FYPO:0008101 ! altered tRNA or precursor level during vegetative growth created_by: vw creation_date: 2024-12-29T15:01:26Z [Term] id: FYPO:0008343 name: increased integrated stress response signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which integrated stress response signaling is increased." [] synonym: "increased GAAC signaling" EXACT [] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: vw creation_date: 2024-12-29T15:11:31Z [Term] id: FYPO:0008344 name: abolished tRNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification does not occur. All tRNA modification may be abolished, or one or more specific tRNA modifications may be selectively affected." [] is_a: FYPO:0000371 ! abolished RNA modification is_a: FYPO:0001765 ! abnormal tRNA modification created_by: vw creation_date: 2024-12-29T15:18:03Z [Term] id: FYPO:0008345 name: abolished tRNA cytidine N4-acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of acety groups to a cytosine N4 residue in a tRNA molecule is abolished." [] is_a: FYPO:0008344 ! abolished tRNA modification created_by: vw creation_date: 2024-12-29T15:22:43Z [Term] id: FYPO:0008346 name: increased cellular potassium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of potassium measured in a cell (total or free) is higher than normal." [] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2024-12-29T15:27:56Z [Term] id: FYPO:0008347 name: increased protein localization to trans-Golgi network def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the trans-Golgi network is increased." [] is_a: FYPO:0003936 ! abnormal protein localization to Golgi apparatus created_by: vw creation_date: 2024-12-29T15:35:45Z [Term] id: FYPO:0008348 name: increased protein localization to pre-vacuolar endosome def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to pre-vacuolar endosome is increased." [] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: vw creation_date: 2024-12-29T15:47:38Z [Term] id: FYPO:0008349 name: abnormal 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of 5'-nucleotidase activity is abnormal." [] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: vw creation_date: 2024-12-29T15:58:10Z [Term] id: FYPO:0008350 name: abolished GMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of GMP 5'-nucleotidase activity is abolished." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:02:25Z [Term] id: FYPO:0008351 name: abolished AMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of AMP 5'-nucleotidase activity is abolished." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:04:42Z [Term] id: FYPO:0008352 name: abolished CMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of CMP 5'-nucleotidase activity is abolished." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:05:55Z [Term] id: FYPO:0008353 name: abolished UMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of UMP 5'-nucleotidase activity is abolished." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:06:30Z [Term] id: FYPO:0008354 name: decreased UMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of UMP 5'-nucleotidase activity is decreased." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:07:10Z [Term] id: FYPO:0008355 name: decreased AMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of AMP 5'-nucleotidase activity is decreased." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:08:06Z [Term] id: FYPO:0008356 name: decreased CMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of CMP 5'-nucleotidase activity is decreased." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:08:50Z [Term] id: FYPO:0008357 name: decreased GMP 5'-nucleotidase activity def: "A molecular function phenotype in which the observed rate of GMP 5'-nucleotidase activity is decreased." [] is_a: FYPO:0008349 ! abnormal 5'-nucleotidase activity created_by: vw creation_date: 2024-12-29T16:09:59Z [Term] id: FYPO:0008358 name: increased protein aggregate level def: "A phenotype in which the amount of protein present as aggregates of misfolded protein is greater than normal." [] is_a: FYPO:0000836 ! increased protein level created_by: vw creation_date: 2024-12-29T16:13:24Z [Term] id: FYPO:0008359 name: increased nucleosome occupancy in gene body def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal within the body of a gene. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PomBase:vw] is_a: FYPO:0007655 ! increased nucleosome occupancy created_by: vw creation_date: 2024-12-31T13:39:33Z [Term] id: FYPO:0008360 name: increased mitophagy during stationary phase def: "A cellular process phenotype in which the occurrence of mitophagy is increased during stationary phase." [PomBase:vw] is_a: FYPO:0000501 ! increased mitophagy created_by: vw creation_date: 2024-12-31T13:45:12Z [Term] id: FYPO:0008361 name: normal integrated stress response signaling def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which integrated stress response signaling is normal (i.e. indistinguishable from wild type)." [PomBase:vw] synonym: "normal GAAC signaling" EXACT [] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: vw creation_date: 2024-12-31T14:00:48Z [Term] id: FYPO:0008362 name: variable cellular lipid droplet content def: "A cell population phenotype in which cells in a population contain variable numbers of lipid droplets. Some cells may contain more or less lipid droplets than normal, while others may lack any detectable lipid droplets." [PomBase:pc] is_a: FYPO:0000003 ! cell population phenotype created_by: vw creation_date: 2025-01-14T12:38:51Z [Term] id: FYPO:0008363 name: abolished nucleolar ring formation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar ring formation does not occur. Nucleolarrings are inclusion bodies located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress or starvation." [] {def="PomBase:vw"} synonym: "abolished nucleolar peripheral inclusion body formation" EXACT [] synonym: "abolished nucleolar ring assembly" EXACT [] is_a: FYPO:0007300 ! abolished protein aggregate center formation created_by: vw creation_date: 2025-01-14T12:48:31Z [Term] id: FYPO:0008364 name: normal histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes is normal (i.e. indistinguishable from wild type)." [PomBase:vw] is_a: FYPO:0003232 ! normal histone H3-K9 methylation during vegetative growth created_by: vw creation_date: 2025-02-28T11:29:20Z [Term] id: FYPO:0008365 name: sensitive to 2-deoxyglucose def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2-deoxyglucose. Cells stop growing (and may die) at a concentration of 2-deoxyglucose that allows wild type cells to grow." [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2025-01-14T12:57:30Z [Term] id: FYPO:0008366 name: decreased duration of heterochromatin maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of heterochromatin maintenance is shorter than normal." [PomBase:vw] is_a: FYPO:0004543 ! abnormal heterochromatin organization during vegetative growth created_by: vw creation_date: 2025-02-28T11:35:53Z [Term] id: FYPO:0008367 name: decreased duration of heterochromatin maintenance involved in chromatin silencing at silent mating type cassette def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of heterochromatin maintenance is shorter than normal in the context of chromatin silencing at silent mating type cassettes." [PomBase:vw] is_a: FYPO:0008366 ! decreased duration of heterochromatin maintenance created_by: vw creation_date: 2025-02-28T11:39:26Z [Term] id: FYPO:0008368 name: abolished histone H3-K9 trimethylation at centromere during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 at a centromere does not occur." [PomBase:vw] is_a: FYPO:0002566 ! abolished histone H3-K9 methylation during vegetative growth created_by: vw creation_date: 2025-02-28T11:45:16Z [Term] id: FYPO:0008369 name: decreased silent mating type cassette heterochromatin tethering to nuclear periphery during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tethering of the silent mating type cassette heterochromatin at the nuclear periphery is decreased." [PomBase:pc] is_a: FYPO:0007768 ! abnormal heterochromatin tethering at nuclear periphery created_by: vw creation_date: 2025-02-28T11:56:15Z [Term] id: FYPO:0008370 name: increased protein localization to cell surface during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is increased during a cellular response to salt stress." [PomBase:pc] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0005173 ! increased protein localization to cell surface created_by: vw creation_date: 2025-02-28T11:59:10Z [Term] id: FYPO:0008371 name: decreased protein localization to cell surface during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is decreased during a cellular response to salt stress." [PomBase:pc] is_a: FYPO:0008258 ! decreased protein localization to cell surface created_by: vw creation_date: 2025-02-28T12:01:31Z [Term] id: FYPO:0008372 name: normal protein localization to cell surface during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is normal (i.e. indistinguishable from wild-type." [PomBase:pb] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0000644 ! normal protein localization during vegetative growth created_by: vw creation_date: 2025-02-28T12:05:09Z [Term] id: FYPO:0008373 name: normal protein localization to cell surface during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is normal (i.e. indistinguishable from wild-type) during a cellular response to salt stress." [PomBase:pb] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0008372 ! normal protein localization to cell surface during vegetative growth created_by: vw creation_date: 2025-02-28T12:13:47Z [Term] id: FYPO:0008374 name: normal phosphatidylinositol-4-phosphate level in the Golgi def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the Golgi is normal (i.e. indistinguishable from wildtype)." [PomBase:pc] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: vw creation_date: 2025-02-28T12:22:20Z [Term] id: FYPO:0008375 name: increased phosphatidylinositol-4-phosphate level in the Golgi def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the Golgi is higher than normal." [] {comment="PomBase:pc"} is_a: FYPO:0001286 ! increased cellular phosphoinositide level created_by: vw creation_date: 2025-02-28T12:28:14Z [Term] id: FYPO:0008376 name: abolished protein localization to cell cortex of cell tip during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips does not occur during a cellular response to osmotic stress." [PomBase:pc] is_a: FYPO:0006502 ! abolished protein localization to cell cortex of cell tip during vegetative growth created_by: vw creation_date: 2025-02-28T12:36:08Z [Term] id: FYPO:0008377 name: abnormal protein distribution along cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is abnormally distributed along the cell tip." [] {comment="PomBase:pc"} is_a: FYPO:0000928 ! abnormal protein localization to cell cortex during vegetative growth created_by: vw creation_date: 2025-02-28T12:38:47Z [Term] id: FYPO:0008378 name: decreased histone H2A phosphorylation during cellular response to camptothecin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during a cellular response to camptothecin. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [] {comment="PomBase:pc"} is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: vw creation_date: 2025-02-28T12:43:52Z [Term] id: FYPO:0008379 name: decreased histone H2A phosphorylation during nitrogen starvation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during a cellular response to nitrogen starvation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:pc] is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: vw creation_date: 2025-02-28T13:01:29Z [Term] id: FYPO:0008380 name: normal histone H2A phosphorylation during cellular response to camptothecin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the extent of histone H2A phosphorylation during a cellular response to camptothecin is normal (i.e. indistinguishable from wild-type)." [PomBase:pc] is_a: FYPO:0002601 ! normal histone H2A phosphorylation during vegetative growth created_by: vw creation_date: 2025-02-28T13:08:56Z [Term] id: FYPO:0008381 name: chromosome region localization phenotype during vegetative growth def: "A cell phenotype that affects the localization of a specific region of a chromosome in a cell in the vegetative growth phase of the life cycle." [PomBase:vw] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0008383 ! chromosome region localization phenotype created_by: vw creation_date: 2025-03-24T11:14:15Z [Term] id: FYPO:0008382 name: abnormal chromosome region phenotype during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a specific region of a chromosome at the nuclear periphery is abnormal." [PomBase:vw] is_a: FYPO:0008381 ! chromosome region localization phenotype during vegetative growth created_by: vw creation_date: 2025-03-24T11:20:00Z [Term] id: FYPO:0008383 name: chromosome region localization phenotype def: "A cell phenotype that affects the localization of a specific region of a chromosome in a cell." [PomBase:vw] is_a: FYPO:0000138 ! localization phenotype created_by: vw creation_date: 2025-03-24T11:37:23Z [Term] id: FYPO:0008384 name: decreased localization of chromatin region to nuclear periphery during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin localization at the nuclear periphery is decreased." [PomBase:vw] is_a: FYPO:0008382 ! abnormal chromosome region phenotype during vegetative growth created_by: vw creation_date: 2025-03-24T11:50:20Z [Term] id: FYPO:0008385 name: abolished nucleophagy during cellular response to Endoplasmic Reticulum stress def: "A cellular process phenotype in which autophagic degradation of the nucleus during Endoplasmic Reticulum stress is abolished." [PMID:37939137] is_a: FYPO:0008085 ! abnormal nucleophagy created_by: vw creation_date: 2025-03-24T12:21:09Z [Term] id: FYPO:0008386 name: decreased nucleophagy def: "A cellular process phenotype in which autophagic degradation of the nucleus is decreased." [PMID:37939137] is_a: FYPO:0008085 ! abnormal nucleophagy created_by: vw creation_date: 2025-03-24T12:27:08Z [Term] id: FYPO:0008387 name: normal protein localization to autophagic structure def: "A cell phenotype in which the localization of a protein to autophagic structure is normal (i.e. indistinguishable from wild type)." [PMID:37939137] is_a: FYPO:0003627 ! normal protein localization created_by: vw creation_date: 2025-03-24T12:32:51Z [Term] id: FYPO:0008388 name: abnormal autophagosomal enclosure during nucleophagy def: "A cellular process phenotype in which the encapsualtion of the autophagosomal cargo by the autophagosomal structure is abnormal." [PMID:37939137] is_a: FYPO:0008082 ! abnormal autophagy created_by: vw creation_date: 2025-03-24T12:36:09Z [Term] id: FYPO:0008389 name: activation of monopolar cell growth at old end during septation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which activation of growth at the old end of a cell happens during cell division, before digestion of the septum." [PMID:34523683] is_a: FYPO:0001393 ! abnormal activation of monopolar cell growth created_by: vw creation_date: 2025-03-24T12:41:43Z [Term] id: FYPO:0008390 name: increased level of histone H3 in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is higher than normal." [PMID:39878217] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: vw creation_date: 2025-03-24T12:50:57Z [Term] id: FYPO:0008391 name: increased level of histone H4 in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H4 measured in the cell is higher than normal." [PMID:39878217] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: vw creation_date: 2025-03-24T12:52:27Z [Term] id: FYPO:0008392 name: normal level of histone H4 in cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H4 measured in the cell is normal (i.e. indistinguishable from wild type)." [PMID:39878217] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: vw creation_date: 2025-03-24T12:54:07Z [Term] id: FYPO:0008393 name: normal cell fusion during mating def: "A cellular process phenotype in which plasma membrane fusion involved in cytogamy is normal (i.e. indistinguishable from wild-type)." [PMID:36202103] is_a: FYPO:0000627 ! normal cellular process created_by: vw creation_date: 2025-04-07T14:44:55Z [Term] id: FYPO:0008394 name: decreased tRNA splicing def: "A cellular process phenotype in which tRNA splicing is decreased. All RNA splicing may be decreased, or one splicing of or more specific tRNA molecules may be selectively affected." [PMID:30228203] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001554 ! abnormal tRNA processing created_by: vw creation_date: 2025-04-07T14:54:06Z [Term] id: FYPO:0008395 name: sensitive to ferrous iron def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ferrous iron ions. Cells stop growing (and may die) at a concentration of iron ions that allows wild type cells to grow." [PMID:35657410] is_a: FYPO:0005825 ! sensitive to iron created_by: vw creation_date: 2025-04-07T15:11:22Z [Term] id: FYPO:0008396 name: sensitive to ferric iron def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ferric iron ions. Cells stop growing (and may die) at a concentration of iron ions that allows wild type cells to grow." [PMID:35657410] is_a: FYPO:0005825 ! sensitive to iron created_by: vw creation_date: 2025-04-07T15:18:41Z [Term] id: FYPO:0008397 name: increased lipid peroxidation def: "A cellular process phenotype in which a lipid peroxidation is increased." [PMID:35657410] is_a: FYPO:0008398 ! abnormal level of cell damage created_by: vw creation_date: 2025-04-07T15:23:52Z [Term] id: FYPO:0008398 name: abnormal level of cell damage def: "A phenotype in which the level of cell damage is abnormal." [PomBase:vw] is_a: FYPO:0000628 ! abnormal cellular process created_by: vw creation_date: 2025-04-07T15:24:57Z [Term] id: FYPO:0008399 name: increased lipid peroxidation during stationary phase def: "A cellular process phenotype in which a lipid peroxidation is increased during stationary phase." [PMID:35657410] is_a: FYPO:0008397 ! increased lipid peroxidation created_by: vw creation_date: 2025-04-07T15:40:28Z [Term] id: FYPO:0008400 name: exocytic vesicles present in decreased numbers at the fusion focus of mating cells def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer exocytic vesicles than normal at the fusion focus of mating cells." [PMID:36202103] is_a: FYPO:0001322 ! abnormal subcellular component during vegetative growth created_by: vw creation_date: 2025-04-07T15:57:26Z [Term] id: FYPO:0008401 name: premature cell separation after cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis begins earlier than normal." [PomBase:vw] is_a: FYPO:0000164 ! abnormal cell separation after cytokinesis created_by: vw creation_date: 2025-04-17T13:51:03Z [Term] id: FYPO:0008402 name: septum assembly during meiosis I def: "A cellular process phenotype in which septum assembly happens during the first division of the meiotic cell cycle." [PMID:16787941] is_a: FYPO:0007260 ! abnormal cellular process during meiotic cell cycle created_by: vw creation_date: 2025-04-17T14:00:06Z [Term] id: FYPO:0008403 name: normal protein degradation during meiosis def: "A cellular process phenotype in which the degradation of a protein is normal (i.e. indistinguishable from wild type) during meiosis. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [PomBase:pc] is_a: FYPO:0002799 ! normal protein degradation created_by: vw creation_date: 2025-04-17T14:09:41Z [Term] id: FYPO:0008404 name: abolished protein degradation during meiosis def: "A cellular process phenotype in which the degradation a protein which is normally degraded during meiosis does not occur. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [PomBase:pc] is_a: FYPO:0002275 ! abnormal protein degradation created_by: vw creation_date: 2025-04-17T14:12:03Z [Term] id: FYPO:0008405 name: abolished protein localization to endoplasmic reticulum def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished." [PomBase:vw] is_a: FYPO:0006377 ! abnormal protein localization to endoplasmic reticulum created_by: vw creation_date: 2025-04-17T14:48:24Z [Term] id: FYPO:0008406 name: abnormal protein localization to endoplasmic reticulum with cytoplasmic aggregation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abnorma and some of the protein is present in the cytoplasmic aggregates instead." [PomBase:vw] is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth created_by: vw creation_date: 2025-04-17T14:53:36Z [Term] id: FYPO:0008407 name: decreased protein localization to endoplasmic reticulum-mitochondrial contact site with increased localization to mitochondrial matrix def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum-mitochondrial contact site is decreased, and some of the protein is localized to the mitochondrion instead." [PomBase:vw] comment: Encompasses both presence of proteins not normally found in the ER and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0003777 ! abnormal protein localization to endoplasmic reticulum during vegetative growth created_by: vw creation_date: 2025-04-17T14:57:07Z [Term] id: FYPO:0008408 name: sensitive to nystatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nystatin. Cells stop growing (and may die) at a concentration of acetic acid that allows wild type cells to grow." [PomBase:vw] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: vw creation_date: 2025-04-17T15:02:41Z [Term] id: FYPO:0008409 name: resistance to ketoconazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ketoconazole than normal." [PomBase:vw] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: vw creation_date: 2025-04-17T15:06:58Z [Term] id: FYPO:0008410 name: increased endoplasmic reticulum unfolded protein response def: "A cellular response phenotype in which a cellular response to endoplasmic unfolded protein resonse is increased in the vegetative growth phase of the life cycle." [PomBase:vw] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: vw creation_date: 2025-04-17T15:13:40Z [Term] id: FYPO:0008411 name: decreased protein phosphorylation during mating def: "A cellular process phenotype observed in a mating cell in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal." [PomBase:pc] is_a: FYPO:0002677 ! abnormal protein phosphorylation created_by: vw creation_date: 2025-04-17T15:17:21Z [Term] id: FYPO:0008412 name: abolished protein phosphorylation during mating def: "A cellular process phenotype in which theophosphorylation of one or more specific proteins, or of specific protein sites, does not occur during conjugation with cellular fusion." [PomBase:vw] is_a: FYPO:0002678 ! abolished protein phosphorylation created_by: vw creation_date: 2025-04-17T15:23:48Z [Term] id: FYPO:0008413 name: increased establishment of chromatin silencing at centromere outer repeat region def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment of chromatin silencing at centromere outer repeat regions is increased." [PomBase:pc] is_a: FYPO:0006299 ! increased chromatin silencing at centromere outer repeat created_by: vw creation_date: 2025-07-01T10:59:15Z [Term] id: FYPO:0008414 name: normal stress granule assembly during glucose starvation def: "A cellular process phenotype in which stress granule assembly is normal (i.e. indistinguishable from wild type) when the cell is subject to glucose starvation." [PomBase:pc] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: vw creation_date: 2025-07-01T11:03:46Z [Term] id: FYPO:0008415 name: abnormal centromeric outer repeat transcript localization to the cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which an RNA transcribed from the centromere outer repeat region is abnormally present in the cytoplasm." [PomBase:pc] is_a: FYPO:0003057 ! abnormal RNA localization created_by: vw creation_date: 2025-07-01T11:06:52Z [Term] id: FYPO:0008416 name: increased histone exchange at silent mating-type cassette during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a higher extent than normal at the silent mating-type cassette. Histone exchange is the replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [PomBase:pc] is_a: FYPO:0007472 ! abnormal histone exchange created_by: vw creation_date: 2025-07-01T11:13:34Z [Term] id: FYPO:0008417 name: increased epigenetic heterochromatin inheritance def: "A phenotype in which a region of the genome that is normally stably assembled and maintained as heterochromatin over successive generations retains heterochromatic structure for more generations than normal." [PomBase:pc] is_a: FYPO:0007477 ! abnormal epigenetic heterochromatin inheritance created_by: vw creation_date: 2025-07-01T11:18:02Z [Term] id: FYPO:0008418 name: abnormal protein localization to heterochromatin island def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more heterochromatin islands is abnormal." [PomBase:pc] is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth created_by: vw creation_date: 2025-07-01T11:25:36Z [Term] id: FYPO:0008419 name: increased protein localization to heterochromatin island def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more heterochromatin island is increased." [PomBase:pc] is_a: FYPO:0008418 ! abnormal protein localization to heterochromatin island created_by: vw creation_date: 2025-07-01T11:36:22Z [Term] id: FYPO:0008420 name: abnormal dolichol-linked oligosaccharide biosynthetic process def: "A cellular metabolic process phenotype in which dolichol-linked oligosaccharide biosynthesis is abnormal." [PomBase:vw] is_a: FYPO:0000860 ! abnormal metabolic process created_by: vw creation_date: 2025-07-01T11:41:12Z [Term] id: FYPO:0008422 name: decreased protein localization to pericentric heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to pericentric heterochromatin is decreased." [PomBase:vw] is_a: FYPO:0002385 ! decreased protein localization to heterochromatin during vegetative growth created_by: vw creation_date: 2025-07-01T11:52:43Z [Term] id: FYPO:0008423 name: increased spatial extent of protein localization to heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to heterochromatin over a different spatial extent than normal. The protein may localize to a larger or smaller region than normal, or its localization may be shifted along the length of the chromosome." [PomBase:vw] is_a: FYPO:0007465 ! altered spatial extent of protein localization to chromatin created_by: vw creation_date: 2025-07-01T12:03:23Z [Term] id: FYPO:0008424 name: decreased silent mating-type cassette transcript-derived siRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of siRNA transcribed from cenH measured in a cell is lower than normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs." [PomBase:vw] synonym: "decreased cenH-derived siRNA level" EXACT [] is_a: FYPO:0004205 ! decreased siRNA level is_a: FYPO:0008251 ! decreased silent mating-type cassette transcript-derived RNA level created_by: vw creation_date: 2025-07-01T18:11:00Z [Term] id: FYPO:0008425 name: increased heterochromatin assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin is increased." [PomBase:vw] is_a: FYPO:0003044 ! abnormal heterochromatin assembly created_by: vw creation_date: 2025-07-01T18:22:40Z [Term] id: FYPO:0008426 name: increased heterochromatin assembly by siRNA def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is increased." [PomBase:pc] synonym: "increased heterochromatin assembly by small RNA" BROAD [] is_a: FYPO:0008425 ! increased heterochromatin assembly created_by: vw creation_date: 2025-07-01T18:25:46Z [Term] id: FYPO:0008427 name: increased protein level during cellular response to sulfur starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to sulfur starvation is higher than normal. Total protein or a specific protein may be affected." [PomBase:vw] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: vw creation_date: 2025-07-01T18:34:15Z [Term] id: FYPO:0008428 name: increased protein phosphorylation during sulfur starvation def: "A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal when the cell is subject to sulfur starvation." [PomBase:vw] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0002680 ! increased protein phosphorylation created_by: vw creation_date: 2025-07-01T18:38:23Z [Term] id: FYPO:0008429 name: normal protein level during cellular response to sulfur starvation def: "A cell phenotype in which the amount of protein measured in a cell that is subject to sulfur starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:vw] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0004083 ! normal protein level created_by: vw creation_date: 2025-07-01T18:41:45Z [Term] id: FYPO:0008430 name: abnormal lipid droplet formation def: "A cellular process phenotype in which any process of lipid droplet formation at the cellular level is abnormal." [PomBase:vw] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: vw creation_date: 2025-07-01T18:49:34Z [Term] id: FYPO:0008431 name: nuclear lipid droplet formation def: "A cellular process phenotype in which lipid droplets are formed in the nucleus." [PomBase:vw] comment: Comment lipid droplets are usually absent from the nucleus is_a: FYPO:0008430 ! abnormal lipid droplet formation created_by: vw creation_date: 2025-07-01T18:54:47Z [Term] id: FYPO:0008432 name: increased level of substance in nucelar membrane def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the nuclear membrane is higher than normal." [PomBase:vw] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2025-07-01T18:59:24Z [Term] id: FYPO:0008433 name: increased inner nuclear membrane phosphatidic acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidic acid measured in the nuclear inner membrane is higher than normal." [PomBase:vw] is_a: FYPO:0008432 ! increased level of substance in nucelar membrane created_by: vw creation_date: 2025-07-01T19:01:47Z [Term] id: FYPO:0008434 name: abnormal mitochondrial ribosome assembly def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which assembly of the mitochondrial ribosomal is abnormal." [PomBase:vw] is_a: FYPO:0005017 ! abnormal ribosome biogenesis created_by: vw creation_date: 2025-07-02T14:59:19Z [Term] id: FYPO:0008435 name: abnormal cytosolic ribosomal large subunit assembly def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which assembly of the cytosolic ribosomal large subunit is abnormal." [PomBase:vw] is_a: FYPO:0005017 ! abnormal ribosome biogenesis created_by: vw creation_date: 2025-07-02T15:08:29Z [Term] id: FYPO:0008436 name: snoRNA guided rRNA 2'-O-methylation level decreased at specific site def: "A cellular process phenotype in which the 2'-O-methylation level of a nucleotide at a specific site in an rRNA molecule is lower than normal." [PomBase:pc] is_a: FYPO:0008111 ! abnormal snRNA modification created_by: vw creation_date: 2025-07-02T15:13:05Z [Term] id: FYPO:0008437 name: RNA mislocalized to nucleolus during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which an RNA that is not normally found in the nucleolus is observed there." [PomBase:pc] is_a: FYPO:0006861 ! mislocalized RNA during vegetative growth created_by: vw creation_date: 2025-07-02T15:17:24Z [Term] id: FYPO:0008438 name: decreased histone H2A phosphorylation during cellular response to methyl methanesulfonate def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during a cellular response to methyl methanesulfonate (MMS). All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased." [PomBase:pc] synonym: "decreased histone H2A phosphorylation during cellular response to MMS" EXACT [] synonym: "fission_yeast_phenotype" EXACT [] is_a: FYPO:0002598 ! decreased histone H2A phosphorylation during vegetative growth created_by: vw creation_date: 2025-07-02T15:24:01Z [Term] id: FYPO:0008439 name: increased histone H2B-K119 ubiquitination during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is increased. Lysine 119 corresponds to the conserved C-terminal lysine of H2B." [PomBase:pc] is_a: FYPO:0002082 ! increased protein ubiquitination during vegetative growth is_a: FYPO:0005607 ! abnormal histone H2B-K119 ubiquitination during vegetative growth created_by: vw creation_date: 2025-08-13T13:08:26Z [Term] id: FYPO:0008441 name: normal protein level during cellular response to replete zinc def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to replete levels of zinc ion is normal (i.e. indistinguishable from wild type). Total protein levels or a specific protein may be affected." [PomBase:pc] is_a: FYPO:0000833 ! normal protein level during vegetative growth created_by: vw creation_date: 2025-08-13T13:35:47Z [Term] id: FYPO:0008442 name: normal growth on ethylenediaminetetraacetic acid def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethylenediaminetetraacetic acid." [] synonym: "normal growth on EDTA" EXACT [] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: vw creation_date: 2025-08-13T14:07:26Z [Term] id: FYPO:0008444 name: increased cellular nicotinic acid adenine dinucleotide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nicotinic acid adenine dinucleotide measured in a cell is higher than normal." [PomBase:vw] synonym: "increased cellular NaAD level" EXACT [] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2025-08-13T16:37:16Z [Term] id: FYPO:0008445 name: increased cellular nicotinic acid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nicotinic acid measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0008447 ! increased cellular vitamin B3 level created_by: vw creation_date: 2025-08-13T16:40:52Z [Term] id: FYPO:0008446 name: increased cellular nicotinamide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nicotinamide measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0008447 ! increased cellular vitamin B3 level created_by: vw creation_date: 2025-08-13T16:45:41Z [Term] id: FYPO:0008447 name: increased cellular vitamin B3 level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount ofviatmin B3 measured in a cell is higher than normal." [PomBase:vw] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: vw creation_date: 2025-08-13T16:48:57Z [Term] id: FYPO:0008449 name: abnormal tRNA modification at postion U34 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification at position U34 is abnormal." [PMID:40829803] is_a: FYPO:0001765 ! abnormal tRNA modification created_by: vw creation_date: 2025-09-26T17:18:34Z [Term] id: FYPO:0008450 name: abnormal tRNA modification at postion A37 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification at position A37 is abnormal." [PMID:40829803] is_a: FYPO:0001765 ! abnormal tRNA modification created_by: vw creation_date: 2025-09-26T17:20:29Z [Term] id: FYPO:0008451 name: abnormal tRNA modification at postion A58 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification at position A58 is abnormal" [PMID:40829803] is_a: FYPO:0001765 ! abnormal tRNA modification created_by: vw creation_date: 2025-09-26T17:21:15Z [Term] id: FYPO:0008452 name: abnormal tRNA modification at postion U46 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification at position U46 is abnormal" [PMID:40829803] is_a: FYPO:0001765 ! abnormal tRNA modification created_by: vw creation_date: 2025-09-26T17:25:02Z [Term] id: FYPO:0008453 name: abolished Golgi cisternae stacking def: "An abnormal Golgi morphology in which the stacking of Golgi cisternae is absent." [PMID:40899782] is_a: FYPO:0000349 ! abnormal Golgi morphology created_by: vw creation_date: 2025-09-26T17:31:36Z [Term] id: FYPO:0008454 name: decreased chromatin silencing at ectopic tethering site def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is decreased at a site where silencing can be triggered by the ectopic tethering of a protein." [PMID:39094570] is_a: FYPO:0002353 ! decreased chromatin silencing created_by: vw creation_date: 2025-09-26T17:36:38Z [Term] id: FYPO:0008455 name: decreased plasma membrane hypoosmotic expansion during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the extent of expansion of the plasma membrane is decreased during hypoosmotic response." [PMID:40629316] is_a: FYPO:0003278 ! abnormal plasma membrane during vegetative growth created_by: vw creation_date: 2025-09-26T17:40:56Z [Term] id: FYPO:0008456 name: normal plasma membrane hypoosmotic expansion during vegetative growth def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the extent of expansion of the plasma membrane is normal during hypoosmotic response." [PMID:40629316] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: vw creation_date: 2025-09-26T17:44:33Z [Term] id: FYPO:0008457 name: normal nucleosome occupancy at long terminal repeat region def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy at long terminal repeat (LTR) regions is normal (i.e. indistinguishable from wild type). Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes." [PMID:30155942] is_a: FYPO:0000856 ! normal nucleosome positioning created_by: vw creation_date: 2025-09-26T17:47:32Z [Term] id: FYPO:0009000 name: decreased rate of cytoplasmic microtubule polymerization during mitotic interphase def: "A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a lower rate, or speed, than normal." [PMID:36633091, PomBase:mlr] synonym: "decreased cytoplasmic microtubule growth rate during mitotic interphase" EXACT [] synonym: "decreased cytoplasmic microtubule growth speed during mitotic interphase" EXACT [] synonym: "decreased cytoplasmic microtubule polymerisation speed during mitotic interphase" EXACT [] synonym: "decreased cytoplasmic microtubule polymerization speed during mitotic interphase" EXACT [] synonym: "decreased rate of cytoplasmic microtubule polymerisation during mitotic interphase" EXACT [] is_a: FYPO:0005703 ! decreased rate of microtubule polymerization during vegetative growth [Term] id: FYPO:0009001 name: decreased duration of cytoplasmic microtubule growth events during mitotic interphase def: "A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which the duration of cytoplasmic microtubule growth events is shorter." [PMID:36633091, PomBase:mlr] synonym: "higher cytoplasmic microtubule catastrophe during mitotic interphase" NARROW [] synonym: "higher cytoplasmic microtubule catastrophe rate during mitotic interphase" NARROW [] synonym: "shorter cytoplasmic microtubule growth events during mitotic interphase" EXACT [] is_a: FYPO:0007956 ! abnormal duration of microtubule growth event [Term] id: FYPO:0009002 name: increased mitochondrial-associated microtubule fraction during mitotic interphase def: "A mitochondrion distribution phenotype observed during mitotic interphase in which the length fraction of cytoplasmic microtubules that is bound to mitochondria is increased with respect to the wild type." [PMID:36633091, PomBase:mlr] synonym: "increased microtubule-associated mitochondrial fraction during mitotic interphase" RELATED [] {comment="They are not exactly the same, but equivalent if total mitochondria and microtubules are the same", created_by="PomBase:mlr"} is_a: FYPO:0000894 ! abnormal intracellular mitochondrion distribution [Term] id: FYPO:0009003 name: abolished nuclear fusion with normal nuclear congression during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur, despite the nuclei and their SPBs coming together." [PMID:36650056, PomBase:mlr] synonym: "nuclear congression without nuclear fusion" EXACT [] is_a: FYPO:0000511 ! abolished nuclear fusion during mating [Term] id: FYPO:0009004 name: horsetail movement with unfused nuclei def: "A cellular process phenotype in which horsetail movement occurs without nuclei fusing. This can happen with both nuclei having congressed and their SPBs having coalesced, but nuclei having failed to fuse, see PMID:36650056." [PMID:36650056, PomBase:mlr] synonym: "horsetail movement with two nuclei" EXACT [] synonym: "twin horsetail nuclei" NARROW [] is_a: FYPO:0000197 ! abnormal horsetail movement [Term] id: FYPO:0009005 name: increased interphase nuclear movement velocity in daughter cell without mitochondria def: "A cellular process phenotype observed in mitotic interphase in which microtubule-based movement oscillations occur at a faster speed than normal in a daughter cell that inherits no mitochondria." [PMID:36633091, PomBase:mlr] synonym: "increased interphase nuclear oscillation velocity in daughter cell without mitochondria" EXACT [] is_a: FYPO:0005461 ! abnormal microtubule-based movement during vegetative growth [Term] id: FYPO:0009006 name: abnormal meiotic cell cycle entry def: "A cellular process phenotype in which a cell enters the meiotic cell cycle without either of the normal steps that precede it: conjugation with cellular fusion and karyogamy with nuclear fusion." [PMID:36650056, PomBase:mlr] is_a: FYPO:0000052 ! abnormal meiotic cell cycle [Term] id: FYPO:0009007 name: decreased vegetative cell population viability def: "A vegetative cell population phenotype in which a lower than normal proportion of cells is viable. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [PMID:34984977, PomBase:mlr] comment: Not to be confused with cell population growth phenotypes, which are measured with culture density or by serial dilution on solid medium. {xref="PomBase:mlr"} synonym: "decreased cell population viability during vegetative growth" EXACT [] is_a: FYPO:0002057 ! cell population viability [Term] id: FYPO:0009008 name: increased vegetative cell population viability def: "A vegetative cell population phenotype in which a larger than normal proportion of cells is viable. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [PMID:34984977, PomBase:mlr] comment: Not to be confused with cell population growth phenotypes, which are measured with culture density or by serial dilution on solid medium. {xref="PomBase:mlr"} synonym: "increased cell population viability during vegetative growth" EXACT [] is_a: FYPO:0002057 ! cell population viability [Term] id: FYPO:0009009 name: decreased cell population growth on arginine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing arginine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on arginine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on arginine nitrogen source" EXACT [PomBase:mlr] synonym: "reduced cell growth on arginine nitrogen source" RELATED [PomBase:mlr] synonym: "slow cell growth on arginine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-16T18:30:11Z [Term] id: FYPO:0009010 name: resistance to UV during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to ultraviolet light." [] synonym: "resistance to ultraviolet light during vegetative growth" EXACT [] is_a: FYPO:0002046 ! resistance to stress property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T17:59:15Z" xsd:dateTime [Term] id: FYPO:0009011 name: increased cell population viability on galactose carbon source def: "A vegetative cell population phenotype in which a larger than normal proportion of cells is viable when grown with galactose as carbon source. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [] comment: Not to be confused with cell population growth phenotypes, which are measured with culture density or by serial dilution on solid medium. synonym: "increased cell population viability during vegetative growth on galactose carbon source" EXACT [] is_a: FYPO:0009008 ! increased vegetative cell population viability property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T18:21:26Z" xsd:dateTime [Term] id: FYPO:0009012 name: decreased vegetative cell population viability on galactose carbon source def: "A vegetative cell population phenotype in which a lower than normal proportion of cells is viable when the medium contains galactose as carbon source. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [PMID:34984977] synonym: "decreased viability on galactose carbon source" BROAD [] is_a: FYPO:0009007 ! decreased vegetative cell population viability [Term] id: FYPO:0009013 name: decreased vegetative cell population viability on glycerol carbon source def: "A vegetative cell population phenotype in which a lower than normal proportion of cells is viable when the medium contains glycerol as carbon source. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [PMID:34984977] synonym: "decreased viability on glycerol carbon source" BROAD [] is_a: FYPO:0009007 ! decreased vegetative cell population viability property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T10:42:14Z" xsd:dateTime [Term] id: FYPO:0009014 name: decreased vegetative cell population viability on xylose carbon source def: "A vegetative cell population phenotype in which a lower than normal proportion of cells is viable when the medium contains xylose as carbon source. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [PMID:34984977] synonym: "decreased viability on xylose carbon source" BROAD [] is_a: FYPO:0009007 ! decreased vegetative cell population viability property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T10:42:40Z" xsd:dateTime [Term] id: FYPO:0009015 name: increased cell population viability on glycerol carbon source def: "A vegetative cell population phenotype in which a larger than normal proportion of cells is viable when grown with glycerol as carbon source. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [] comment: Not to be confused with cell population growth phenotypes, which are measured with culture density or by serial dilution on solid medium. synonym: "increased cell population viability during vegetative growth on glycerol carbon source" EXACT [] is_a: FYPO:0009008 ! increased vegetative cell population viability property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T18:21:47Z" xsd:dateTime [Term] id: FYPO:0009016 name: increased cell population viability on xylose carbon source def: "A vegetative cell population phenotype in which a larger than normal proportion of cells is viable when grown with xylose as carbon source. In High Throughput Phenotyping this is typically assessed using phloxine as a dye." [] comment: Not to be confused with cell population growth phenotypes, which are measured with culture density or by serial dilution on solid medium. synonym: "increased cell population viability during vegetative growth on xylose carbon source" EXACT [] is_a: FYPO:0009008 ! increased vegetative cell population viability property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T18:21:58Z" xsd:dateTime [Term] id: FYPO:0009017 name: reduced viability in stationary phase upon glucose starvation in the presence of cadmium def: "A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase, when subjected to glucose starvation and when cadmium is present in the medium in a higher proportion than usual." [] is_a: FYPO:0005231 ! loss of viability in stationary phase upon glucose starvation property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T12:59:43Z" xsd:dateTime [Term] id: FYPO:0009018 name: increased viability in stationary phase upon glucose starvation in the presence of cadmium def: "A cell population phenotype in which a higher than normal proportion of cells in the population remains viable after entering stationary phase, when subjected to glucose starvation and when cadmium is present in the medium in a higher proportion than usual." [] is_a: FYPO:0001309 ! increased viability in stationary phase property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T14:12:02Z" xsd:dateTime [Term] id: FYPO:0009019 name: increased vegetative cell population binucleate index def: "A vegetative cell population phenotype in which the poportion of cells with two nuclei is higher than normal." [PMID:34984977] synonym: "higher proportion of binucleate cells during vegetative growth" EXACT [] synonym: "more cells with two nuclei during vegetative growth" EXACT [] is_a: FYPO:0000003 ! cell population phenotype property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T14:29:19Z" xsd:dateTime [Term] id: FYPO:0009020 name: decreased vegetative cell population binucleate index def: "A vegetative cell population phenotype in which the poportion of cells with two nuclei is lower than normal." [PMID:34984977] synonym: "less cells with two nuclei during vegetative growth" EXACT [] synonym: "lower proportion of binucleate cells during vegetative growth" EXACT [] is_a: FYPO:0000003 ! cell population phenotype property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-17T14:29:35Z" xsd:dateTime [Term] id: FYPO:0009021 name: decreased cell population growth on cysteine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-cysteine as the nitrogen source." [PMID:34984977, PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on cysteine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on cysteine nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with cysteine nitrogen source" RELATED [PomBase:mlr] synonym: "reduced cell growth on cysteine nitrogen source" RELATED [PomBase:mlr] synonym: "slow cell growth on cysteine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009022 name: decreased cell population growth on isoleucine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-isoleucine as the nitrogen source." [PMID:34984977, PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on isoleucine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on isoleucine nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with isoleucine nitrogen source" RELATED [PomBase:mlr] synonym: "reduced cell growth on isoleucine nitrogen source" RELATED [PomBase:mlr] synonym: "slow cell growth on isoleucine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009023 name: decreased cell population growth on methionine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-methionine as the nitrogen source." [PMID:34984977, PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on methionine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on methionine nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with methionine nitrogen source" RELATED [PomBase:mlr] synonym: "reduced cell growth on methionine nitrogen source" RELATED [PomBase:mlr] synonym: "slow cell growth on methionine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009024 name: increased cell population growth on cysteine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing cysteine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on cysteine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on cysteine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009025 name: increased cell population growth on isoleucine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing isoleucine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on isoleucine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on isoleucine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009026 name: increased cell population growth on methionine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing methionine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on methionine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on methionine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009027 name: increased cell population growth on phenylalanine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing phenylalanine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on phenylalanine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on phenylalanine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009028 name: increased cell population growth on proline nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing proline as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on proline nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on proline nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009029 name: increased cell population growth on arginine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing arginine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on arginine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on arginine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009030 name: resistance to amitrole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amitrole than normal." [PomBase:mlr] synonym: "resistance to amitrole during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to amitrole during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to amitrole" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009031 name: resistance to bleomycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of bleomycin than normal." [PomBase:mlr] synonym: "resistance to bleomycin during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to bleomycin during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to bleomycin" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009032 name: resistance to bortezomib def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of bortezomib than normal." [PomBase:mlr] synonym: "resistance to bortezomib during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to bortezomib during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to bortezomib" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009033 name: resistance to dihydrocoumarin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of dihydrocoumarin than normal." [PomBase:mlr] synonym: "resistance to dihydrocoumarin during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to dihydrocoumarin during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to dihydrocoumarin" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009034 name: resistance to ethylenediaminetetraacetic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethylenediaminetetraacetic acid than normal." [PomBase:mlr] synonym: "resistance to ethylenediaminetetraacetic acid during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to ethylenediaminetetraacetic acid during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to ethylenediaminetetraacetic acid" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009035 name: resistance to formamide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of formamide than normal." [PomBase:mlr] synonym: "resistance to formamide during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to formamide during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to formamide" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009036 name: resistance to benzamidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of benzamidine than normal." [PomBase:mlr] synonym: "resistance to benzamidine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to benzamidine during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to benzamidine" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009037 name: resistance to phloxine B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phloxine B than normal." [PomBase:mlr] synonym: "resistance to phloxine B during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to phloxine B during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to phloxine B" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009038 name: resistance to egtazic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of egtazic acid than normal." [PomBase:mlr] synonym: "resistance to egtazic acid during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to egtazic acid during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to egtazic acid" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009039 name: resistance to potassium chloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of potassium chloride than normal." [PomBase:mlr] synonym: "resistance to potassium chloride during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to potassium chloride during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to potassium chloride" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009040 name: resistance to tea tree oil def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tea tree oil than normal." [PomBase:mlr] synonym: "resistance to tea tree oil during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to tea tree oil during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to tea tree oil" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009041 name: resistance to 2,2′-dipyridyl def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 2,2′-dipyridyl than normal." [PomBase:mlr] synonym: "resistance to 2,2′-dipyridyl during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to 2,2′-dipyridyl during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to 2,2′-dipyridyl" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009042 name: resistance to sorbitol def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sorbitol than normal." [PomBase:mlr] synonym: "resistance to sorbitol during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to sorbitol during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to sorbitol" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009043 name: resistance to potassium chloride and sodium dodecyl sulfate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of potassium chloride and sodium dodecyl sulfate than normal." [PomBase:mlr] synonym: "resistance to potassium chloride and sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to potassium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to potassium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] synonym: "resistant to potassium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T17:54:07Z [Term] id: FYPO:0009044 name: resistance to sodium chloride and methyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of sodium chloride and methyl methanesulfonate than normal." [PomBase:mlr] synonym: "resistance to sodium chloride and methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to sodium chloride and methyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to sodium chloride and methyl methanesulfonate in combination" EXACT [PomBase:mlr] synonym: "resistant to sodium chloride and methyl methanesulfonate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T17:54:07Z [Term] id: FYPO:0009045 name: resistance to calcofluor and potassium chloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of calcofluor and potassium chloride than normal." [PomBase:mlr] synonym: "resistance to calcofluor and potassium chloride during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to calcofluor and potassium chloride during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to calcofluor and potassium chloride in combination" EXACT [PomBase:mlr] synonym: "resistant to calcofluor and potassium chloride" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T17:54:07Z [Term] id: FYPO:0009046 name: resistance to phloxine B and hydrogen peroxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of phloxine B and hydrogen peroxide than normal." [PomBase:mlr] synonym: "resistance to phloxine B and hydrogen peroxide during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to phloxine B and hydrogen peroxide during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to phloxine B and hydrogen peroxide in combination" EXACT [PomBase:mlr] synonym: "resistant to phloxine B and hydrogen peroxide" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2023-02-17T17:54:07Z [Term] id: FYPO:0009047 name: resistance to dimethyl sulfoxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of dimethyl sulfoxide than normal." [PomBase:mlr] synonym: "resistance to dimethyl sulfoxide during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to dimethyl sulfoxide during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to dimethyl sulfoxide" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009048 name: resistance to cysteine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cysteine than normal." [PomBase:mlr] comment: To be annotated in situations where the aminoacid is used as a drug (high concentrations), not as a carbon/sulfur/nitrogen source. synonym: "resistance to cysteine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to cysteine during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to cysteine" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009049 name: resistance to methionine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methionine than normal." [PomBase:mlr] comment: To be annotated in situations where the aminoacid is used as a drug (high concentrations), not as a carbon/sulfur/nitrogen source. synonym: "resistance to methionine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to methionine during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to methionine" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-02-17T16:54:15Z [Term] id: FYPO:0009050 name: resistance to hydroxyurea and methyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of hydroxyurea and methyl methanesulfonate than normal." [PomBase:mlr] synonym: "resistance to hydroxyurea and methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to hydroxyurea and methyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to hydroxyurea and methyl methanesulfonate in combination" EXACT [PomBase:mlr] synonym: "resistant to hydroxyurea and methyl methanesulfonate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: midori creation_date: 2023-02-17T17:54:07Z [Term] id: FYPO:0009051 name: increased cell population growth on ammonium nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing ammonium as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on ammonium nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on ammonium nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009052 name: increased cell population growth on glutamate nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing glutamate as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on glutamate nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on glutamate nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009053 name: decreased cell population growth on glutamate nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-glutamate as the nitrogen source." [PMID:34984977, PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on glutamate nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on glutamate nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with glutamate nitrogen source" RELATED [PomBase:mlr] synonym: "reduced cell growth on glutamate nitrogen source" RELATED [PomBase:mlr] synonym: "slow cell growth on glutamate nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-02-17T15:43:28Z [Term] id: FYPO:0009054 name: increased viabilitiy in stationary phase upon glucose starvation def: "A cell population phenotype in which a higher than normal proportion of cells in the population remains viable after entering stationary phase, when subjected to glucose starvation." [] is_a: FYPO:0001309 ! increased viability in stationary phase property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-02-23T11:45:24Z" xsd:dateTime [Term] id: FYPO:0009055 name: resistance to ethyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethyl methanesulfonate than normal." [PomBase:mlr] synonym: "resistance to ethyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to ethyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to ethyl methanesulfonate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-03-03T16:54:15Z [Term] id: FYPO:0009056 name: decreased kinetochore microtubule depolymerization during mitotic anaphase A def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore microtubule depolymerization, i.e. the removal of tubulin dimers from a kinetochore microtubule, occurs to a lesser extent than normal during anaphase A. Kinetochore microtubule depolymerisation drives chromosome movement during Anaphase A in S. pombe." [PMID:36435910] is_a: FYPO:0005423 ! decreased mitotic spindle microtubule depolymerization during mitotic anaphase A property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-04-20T15:23:30Z" xsd:dateTime [Term] id: FYPO:0009057 name: decreased rate of microtubule catastrophe involved in meitotic centromere clustering during meiotic prophase I def: "A cellular process in which catastrophe rate (i.e. the frequency of transition from pause or growth to shrinkage) of microtubules is lower than normal as part of centromere clustering during meiotic prophase I." [PMID:36435910] is_a: FYPO:0009058 ! decreased microtubule depolymerisation involved in meitotic centromere clustering during meiotic prophase I property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-04-20T15:30:44Z" xsd:dateTime [Term] id: FYPO:0009058 name: decreased microtubule depolymerisation involved in meitotic centromere clustering during meiotic prophase I def: "A cellular process in which depolymerization (i.e. removal of tubulin dimers) of microtubules as part of centromere clustering during meiotic prophase I is decreased with respect to normal. This can happen due to lower catastrophe rate or depolymerisation speed." [PMID:23770679, PMID:36435910] is_a: FYPO:0007113 ! abnormal microtubule cytoskeleton organization during meiotic cell cycle property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-04-20T15:31:31Z" xsd:dateTime [Term] id: FYPO:0009059 name: increased protein localization to cell cortex during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is increased." [PMID:36749320] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "higher protein localization to cell cortex during vegetative growth" EXACT [] synonym: "increased protein localisation to cell cortex during vegetative growth" EXACT [] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-04-20T16:48:53Z" xsd:dateTime [Term] id: FYPO:0009060 name: resistance to wortmannin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of wortmannin than normal." [PMID:26891792] synonym: "resistance to wortmannin during vegetative growth" EXACT [] synonym: "resistant to wortmannin" EXACT [] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-21T13:31:18Z" xsd:dateTime [Term] id: FYPO:0009061 name: increased protein localization to cell cortex during mitotic interphase def: "A cell phenotype observed in mitotic interphase in which the localization of a protein to the cell cortex is increased." [] comment: higher protein localization to cell cortex during mitotic interphase comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cell cortex during mitotic interphase" EXACT [] is_a: FYPO:0009059 ! increased protein localization to cell cortex during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-21T13:38:07Z" xsd:dateTime [Term] id: FYPO:0009062 name: resistance to X-rays during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to X-rays." [] synonym: "increased vegetative cell population growth during cellular response to X rays" EXACT [] synonym: "increased vegetative cell population growth during cellular response to X-rays" EXACT [] synonym: "resistant to X rays during vegetative growth" EXACT [] synonym: "resistant to X-rays during vegetative growth" EXACT [] is_a: FYPO:0002312 ! resistance to ionizing radiation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-26T09:46:47Z" xsd:dateTime [Term] id: FYPO:0009063 name: sensitive to X-rays during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to X-rays." [] synonym: "decreased vegetative cell population growth during cellular response to X rays" EXACT [] synonym: "decreased vegetative cell population growth during cellular response to X-rays" EXACT [] synonym: "sensitive to X rays during vegetative growth" EXACT [] is_a: FYPO:0000267 ! sensitive to ionizing radiation during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-26T09:49:57Z" xsd:dateTime [Term] id: FYPO:0009064 name: sensitive to X-rays and rapamycin during vegetative growth. def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of X-rays and ramapycin." [] synonym: "decreased vegetative cell population growth when treated with rapamycin and X-rays" EXACT [] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth is_a: FYPO:0000304 ! sensitive to stress during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-26T09:56:59Z" xsd:dateTime [Term] id: FYPO:0009065 name: resistance to X-rays and rapamycin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to a combination of X-rays and ramapycin." [] synonym: "increased vegetative cell population growth when treated with rapamycin and X-rays" EXACT [] synonym: "resistant to X-rays and rapamycin during vegetative growth" EXACT [] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth is_a: FYPO:0000850 ! resistance to stress during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-26T10:41:28Z" xsd:dateTime [Term] id: FYPO:0009066 name: resistance to amorolfine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amorolfine than normal." [PomBase:mlr] synonym: "resistance to amorolfine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to amorolfine during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to amorolfine" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-26T11:08:00.776Z [Term] id: FYPO:0009067 name: sensitive to amorolfine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amorolfine. Cells stop growing (and may die) at a concentration of amorolfine that allows wild type cells to grow." [PomBase:mlr] synonym: "hypersensitive to amorolfine" EXACT [PomBase:mlr] synonym: "sensitive to amorolfine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "sensitive to amorolfine during vegetative growth" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-26T11:08:02.768Z [Term] id: FYPO:0009068 name: resistance to ciclopirox olamine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ciclopirox olamine than normal." [PomBase:mlr] synonym: "resistance to ciclopirox olamine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to ciclopirox olamine during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to ciclopirox olamine" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-26T11:08:18.672Z [Term] id: FYPO:0009069 name: sensitive to ciclopirox olamine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ciclopirox olamine. Cells stop growing (and may die) at a concentration of ciclopirox olamine that allows wild type cells to grow." [PomBase:mlr] synonym: "hypersensitive to ciclopirox olamine" EXACT [PomBase:mlr] synonym: "sensitive to ciclopirox olamine during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "sensitive to ciclopirox olamine during vegetative growth" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-26T11:08:21.241Z [Term] id: FYPO:0009070 name: resistance to itraconazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of itraconazole than normal." [PomBase:mlr] synonym: "resistance to itraconazole during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to itraconazole during vegetative growth" EXACT [PomBase:mlr] synonym: "resistant to itraconazole" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-26T11:09:04.171Z [Term] id: FYPO:0009071 name: sensitive to itraconazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to itraconazole. Cells stop growing (and may die) at a concentration of itraconazole that allows wild type cells to grow." [PomBase:mlr] synonym: "hypersensitive to itraconazole" EXACT [PomBase:mlr] synonym: "sensitive to itraconazole during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "sensitive to itraconazole during vegetative growth" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-26T11:09:06.265Z [Term] id: FYPO:0009072 name: increased cell population growth on lysine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lysine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on lysine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on lysine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:14:03.000Z [Term] id: FYPO:0009073 name: decreased cell population growth on lysine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing lysine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on lysine nitrogen source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on lysine nitrogen source" EXACT [PomBase:mlr] synonym: "growth defect, slow growth with lysine nitrogen source" RELATED [PomBase:mlr] synonym: "reduced cell growth on lysine nitrogen source" RELATED [PomBase:mlr] synonym: "slow cell growth on lysine nitrogen source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:14:07.574Z [Term] id: FYPO:0009074 name: increased cell population growth on serine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing serine as the nitrogen source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on serine nitrogen source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on serine nitrogen source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:15:26.425Z [Term] id: FYPO:0009075 name: decreased cell population growth on fructose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing fructose as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on fructose carbon source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on fructose carbon source" EXACT [PomBase:mlr] synonym: "reduced cell growth on fructose carbon source" RELATED [PomBase:mlr] synonym: "slow cell growth on fructose carbon source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:38:49.433Z [Term] id: FYPO:0009076 name: increased cell population growth on sucrose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing sucrose as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on sucrose carbon source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on sucrose carbon source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:40:12.616Z [Term] id: FYPO:0009077 name: increased cell population growth on ethanol carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing ethanol as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on ethanol carbon source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on ethanol carbon source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:43:35.578Z [Term] id: FYPO:0009078 name: decreased cell population growth on ethanol carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing ethanol as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on ethanol carbon source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on ethanol carbon source" EXACT [PomBase:mlr] synonym: "reduced cell growth on ethanol carbon source" RELATED [PomBase:mlr] synonym: "slow cell growth on ethanol carbon source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-26T11:43:39.145Z [Term] id: FYPO:0009079 name: resistance to calcofluor and sodium dodecyl sulfate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of calcofluor and sodium dodecyl sulfate than normal." [PomBase:mlr] synonym: "resistance to calcofluor and SDS" EXACT [PomBase:mlr] synonym: "resistance to calcofluor and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to calcofluor and SDS in combination" EXACT [PomBase:mlr] synonym: "resistance to calcofluor and sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to calcofluor and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to calcofluor and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] synonym: "resistant to calcofluor and SDS" EXACT [PomBase:mlr] synonym: "resistant to calcofluor and sodium dodecyl sulfate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:06:49.010Z [Term] id: FYPO:0009080 name: sensitive to calcofluor and sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of calcofluor and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of calcofluor and sodium dodecyl sulfate that allow wild type cells to grow." [] synonym: "hypersensitive to calcofluor and SDS" EXACT [PomBase:mlr] synonym: "hypersensitive to calcofluor and sodium dodecyl sulfate" EXACT [PomBase:mlr] synonym: "sensitive to calcofluor and SDS" EXACT [PomBase:mlr] synonym: "sensitive to calcofluor and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to calcofluor and SDS in combination" EXACT [PomBase:mlr] synonym: "sensitive to calcofluor and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to calcofluor and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:07:37.303Z [Term] id: FYPO:0009081 name: resistance to potassium chloride and methyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of potassium chloride and methyl methanesulfonate than normal." [PomBase:mlr] synonym: "resistance to potassium chloride and methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to potassium chloride and methyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to potassium chloride and methyl methanesulfonate in combination" EXACT [PomBase:mlr] synonym: "resistance to potassium chloride and MMS" EXACT [PomBase:mlr] synonym: "resistance to potassium chloride and MMS during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to potassium chloride and MMS in combination" EXACT [PomBase:mlr] synonym: "resistant to potassium chloride and methyl methanesulfonate" EXACT [PomBase:mlr] synonym: "resistant to potassium chloride and MMS" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:10:09.427Z [Term] id: FYPO:0009082 name: sensitive to potassium chloride and methyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of potassium chloride and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of potassium chloride and methyl methanesulfonate that allow wild type cells to grow." [] synonym: "hypersensitive to potassium chloride and methyl methanesulfonate" EXACT [PomBase:mlr] synonym: "hypersensitive to potassium chloride and MMS" EXACT [PomBase:mlr] synonym: "sensitive to potassium chloride and methyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to potassium chloride and methyl methanesulfonate in combination" EXACT [PomBase:mlr] synonym: "sensitive to potassium chloride and MMS" EXACT [PomBase:mlr] synonym: "sensitive to potassium chloride and MMS during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to potassium chloride and MMS in combination" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:10:12.509Z [Term] id: FYPO:0009083 name: resistance to lithium chloride and methyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of lithium chloride and methyl methanesulfonate than normal." [PomBase:mlr] synonym: "resistance to lithium chloride and methyl methanesulfonate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to lithium chloride and methyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and methyl methanesulfonate in combination" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and MMS" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and MMS during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and MMS in combination" EXACT [PomBase:mlr] synonym: "resistant to lithium chloride and methyl methanesulfonate" EXACT [PomBase:mlr] synonym: "resistant to lithium chloride and MMS" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:10:51.829Z [Term] id: FYPO:0009084 name: sensitive to lithium chloride and methyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of lithium chloride and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of lithium chloride and methyl methanesulfonate that allow wild type cells to grow." [] synonym: "hypersensitive to lithium chloride and methyl methanesulfonate" EXACT [PomBase:mlr] synonym: "hypersensitive to lithium chloride and MMS" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and methyl methanesulfonate during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and methyl methanesulfonate in combination" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and MMS" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and MMS during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and MMS in combination" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:10:54.519Z [Term] id: FYPO:0009085 name: resistance to lithium chloride and sodium dodecyl sulfate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of lithium chloride and sodium dodecyl sulfate than normal." [PomBase:mlr] synonym: "resistance to lithium chloride and SDS" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and SDS in combination" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to lithium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to lithium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] synonym: "resistant to lithium chloride and SDS" EXACT [PomBase:mlr] synonym: "resistant to lithium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:11:44.342Z [Term] id: FYPO:0009086 name: sensitive to lithium chloride and sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of lithium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of lithium chloride and sodium dodecyl sulfate that allow wild type cells to grow." [] synonym: "hypersensitive to lithium chloride and SDS" EXACT [PomBase:mlr] synonym: "hypersensitive to lithium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and SDS" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and SDS in combination" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to lithium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:11:47.145Z [Term] id: FYPO:0009087 name: resistance to magnesium chloride and sodium dodecyl sulfate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of magnesium chloride and sodium dodecyl sulfate than normal." [PomBase:mlr] synonym: "resistance to magnesium chloride and SDS" EXACT [PomBase:mlr] synonym: "resistance to magnesium chloride and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to magnesium chloride and SDS in combination" EXACT [PomBase:mlr] synonym: "resistance to magnesium chloride and sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to magnesium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to magnesium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] synonym: "resistant to magnesium chloride and SDS" EXACT [PomBase:mlr] synonym: "resistant to magnesium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:13:03.158Z [Term] id: FYPO:0009088 name: sensitive to magnesium chloride and sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of magnesium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of magnesium chloride and sodium dodecyl sulfate that allow wild type cells to grow." [] synonym: "hypersensitive to magnesium chloride and SDS" EXACT [PomBase:mlr] synonym: "hypersensitive to magnesium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] synonym: "sensitive to magnesium chloride and SDS" EXACT [PomBase:mlr] synonym: "sensitive to magnesium chloride and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to magnesium chloride and SDS in combination" EXACT [PomBase:mlr] synonym: "sensitive to magnesium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to magnesium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:13:07.832Z [Term] id: FYPO:0009089 name: resistance to sodium chloride and sodium dodecyl sulfate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of sodium chloride and sodium dodecyl sulfate than normal." [PomBase:mlr] synonym: "resistance to sodium chloride and SDS" EXACT [PomBase:mlr] synonym: "resistance to sodium chloride and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to sodium chloride and SDS in combination" EXACT [PomBase:mlr] synonym: "resistance to sodium chloride and sodium dodecyl sulfate during mitotic cell cycle" RELATED [PomBase:mlr] synonym: "resistance to sodium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "resistance to sodium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] synonym: "resistant to sodium chloride and SDS" EXACT [PomBase:mlr] synonym: "resistant to sodium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] is_a: FYPO:0000126 ! increased resistance to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:13:44.920Z [Term] id: FYPO:0009090 name: sensitive to sodium chloride and sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of sodium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of sodium chloride and sodium dodecyl sulfate that allow wild type cells to grow." [] synonym: "hypersensitive to sodium chloride and SDS" EXACT [PomBase:mlr] synonym: "hypersensitive to sodium chloride and sodium dodecyl sulfate" EXACT [PomBase:mlr] synonym: "sensitive to sodium chloride and SDS" EXACT [PomBase:mlr] synonym: "sensitive to sodium chloride and SDS during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to sodium chloride and SDS in combination" EXACT [PomBase:mlr] synonym: "sensitive to sodium chloride and sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mlr] synonym: "sensitive to sodium chloride and sodium dodecyl sulfate in combination" EXACT [PomBase:mlr] is_a: FYPO:0000127 ! increased sensitivity to chemical during vegetative growth created_by: PomBase:mlr creation_date: 2023-06-27T09:13:47.596Z [Term] id: FYPO:0009091 name: decreased cell population growth on lysine and proline nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing lysine and proline as nitrogen sources." [] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased vegetative cell growth on lysine and proline nitrogen source" EXACT [] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-27T09:24:28Z" xsd:dateTime [Term] id: FYPO:0009092 name: decreased cell population growth on lysine and serine nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing lysine and serine as nitrogen sources." [] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased vegetative cell growth on lysine and serine nitrogen source" EXACT [] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-27T09:27:22Z" xsd:dateTime [Term] id: FYPO:0009093 name: increased cell population growth on lysine and serine nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lysine and serine as the nitrogen sources." [] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased vegetative cell growth on lysine and serine nitrogen source" EXACT [] is_a: FYPO:0004557 ! increased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-27T09:30:41Z" xsd:dateTime [Term] id: FYPO:0009094 name: increased cell population growth on lysine and proline nitrogen source def: "A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lysine and proline as the nitrogen sources." [] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased vegetative cell growth on lysine and proline nitrogen source" EXACT [] is_a: FYPO:0004557 ! increased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-27T09:35:00Z" xsd:dateTime [Term] id: FYPO:0009095 name: increased cell population growth on fructose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing fructose as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on fructose carbon source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on fructose carbon source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-27T11:36:40.485Z [Term] id: FYPO:0009096 name: increased cell population growth on xylose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing xylose as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on xylose carbon source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on xylose carbon source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-27T14:52:19.614Z [Term] id: FYPO:0009097 name: decreased cell population growth on xylose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing xylose as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on xylose carbon source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on xylose carbon source" EXACT [PomBase:mlr] synonym: "reduced cell growth on xylose carbon source" RELATED [PomBase:mlr] synonym: "slow cell growth on xylose carbon source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-27T14:52:22.767Z [Term] id: FYPO:0009098 name: increased cell population growth on mannitol carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing mannitol as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "increased growth on mannitol carbon source" BROAD [PomBase:mlr] synonym: "increased vegetative cell growth on mannitol carbon source" EXACT [PomBase:mlr] is_a: FYPO:0004557 ! increased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-27T14:53:36.402Z [Term] id: FYPO:0009099 name: decreased cell population growth on mannitol carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing mannitol as the carbon source." [PomBase:mlr] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on mannitol carbon source" BROAD [PomBase:mlr] synonym: "decreased vegetative cell growth on mannitol carbon source" EXACT [PomBase:mlr] synonym: "reduced cell growth on mannitol carbon source" RELATED [PomBase:mlr] synonym: "slow cell growth on mannitol carbon source" NARROW [PomBase:mlr] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: PomBase:mlr creation_date: 2023-06-27T14:53:39.811Z [Term] id: FYPO:0009100 name: decreased cell population growth on glycerol and galactose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol and galactose carbon sources." [] synonym: "decreased vegetative cell growth on glycerol and galactose carbon source" EXACT [] is_a: FYPO:0001355 ! decreased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-27T15:03:01Z" xsd:dateTime [Term] id: FYPO:0009101 name: increased cell population growth on glycerol and galactose carbon source def: "A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing glycerol and galactose carbon sources." [] synonym: "increased vegetative cell growth on glycerol and galactose carbon source" EXACT [] is_a: FYPO:0004557 ! increased vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-27T15:05:00Z" xsd:dateTime [Term] id: FYPO:0009102 name: interphase microtubules present in decreased numbers def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain less cytoplasmic microtubules than normal during interphase of the mitotic cell cycle." [] synonym: "decreased number of interphase microtubules" EXACT [] synonym: "fewer microtubules present during mitotic interphase" EXACT [] is_a: FYPO:0003430 ! microtubules present in decreased numbers property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-29T10:32:36Z" xsd:dateTime [Term] id: FYPO:0009103 name: increased actomyosin contractile ring recoil distance after ring ablation def: "A cell phenotype in which the recoil distance of the cytokynetic ring after ring ablation is increased with respect to wild type. Experimentally, a localised cut or ablation is typically achieved using a laser. This distance, in combination with the timing of recoil are used to compute effective stiffness and drag of the ring components. See PMID:36980258." [] synonym: "increased cytokinetic ring recoil distance after laser ablation" BROAD [] xref: PMID:36980258 is_a: FYPO:0004736 ! abnormal actomyosin contractile ring property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-29T10:36:53Z" xsd:dateTime [Term] id: FYPO:0009104 name: increased actomyosin contractile ring recoil time after ring ablation def: "A cell phenotype in which the recoil time of the cytokynetic ring after ring ablation is increased with respect to wild type. Experimentally, a localised cut or ablation is typically achieved using a laser. The recoil time is the time it takes the recoil to stop after laser ablation. This timing, in combination with the recoil distance are used to compute effective stiffness and drag of the ring components. See PMID:36980258." [] synonym: "increased cytokinetic ring recoil distance after laser ablation" BROAD [] xref: PMID:36980258 is_a: FYPO:0004736 ! abnormal actomyosin contractile ring property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-06-29T10:38:29Z" xsd:dateTime [Term] id: FYPO:0009105 name: mislocalized nucleus during mitotic telophase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the divided nuclei are mislocalized during telophase of the mitotic cell cycle." [PMID:37099380] synonym: "abnormal nuclei location during mitotic telophase" EXACT [] synonym: "abnormal nucleus location during mitotic telophase" EXACT [] synonym: "abnormal nucleus position during mitotic telophase" EXACT [] synonym: "abnormal nucleus positioning during mitotic telophase" EXACT [] synonym: "mislocalised nuclei during mitotic telophase" EXACT [] synonym: "mislocalised nucleus during mitotic telophase" EXACT [] is_a: FYPO:0002071 ! mislocalized nucleus during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-03T10:13:41Z" xsd:dateTime [Term] id: FYPO:0009106 name: nucleus mislocalized towards cell equator during mitotic telophase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the divided nuclei are located closer to the cell equator during telophase of the mitotic cell cycle when compared to wild-type cells." [PMID:37099380] synonym: "nuclear displaced towards cell equator during mitotic telophase" EXACT [] synonym: "nuclear displaced towards cytokinetic ring during mitotic telophase" EXACT [] synonym: "nuclear displacement towards cell equator during mitotic telophase" EXACT [] synonym: "nuclear displacement towards cytokinetic ring during mitotic telophase" EXACT [] is_a: FYPO:0009105 ! mislocalized nucleus during mitotic telophase property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-03T10:21:38Z" xsd:dateTime [Term] id: FYPO:0009107 name: increased nuclear movement velocity during mitotic telophase def: "A cellular process phenotype observed in mitotic interphase in which the microtubule-driven movement of daughter nuclei away from the cell tips after mitotic spindle dissambly occurs at a faster speed than normal during telophase." [PMID:37099380] synonym: "increased nuclear displacement speed during telophase" EXACT [] synonym: "increased nuclear displacement velocity during telophase" EXACT [] synonym: "increased nuclear movement speed during telophase" EXACT [] is_a: FYPO:0005461 ! abnormal microtubule-based movement during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-03T10:39:37Z" xsd:dateTime [Term] id: FYPO:0009108 name: abnormal spindle pole body orientation during mitotic telophase def: "A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the spindle pole bodies (SPBs) of daughter nuclei are misoriented during mitotic telophase. Normally, SPBs face the cell tips at the end of anaphase when the spindle disassembles, but as microtubules are nucleated from SPBs and telophase nuclear positioning proceeds, the SPBs tend to face the cell equator." [PMID:37099380] synonym: "abnormal spindle pole body angle during mitotic telophase" EXACT [] synonym: "abnormal spindle pole body positioning within the nucleus during mitotic telophase" EXACT [] synonym: "spindle pole body facing cell tips during mitotic telophase" RELATED [] is_a: FYPO:0000136 ! cellular physical quality phenotype property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-03T10:51:11Z" xsd:dateTime [Term] id: FYPO:0009109 name: decreased vegetative cell population growth after short incubation in hydroxyurea def: "A cell growth phenotype in which cell population growth is decreased relative to normal after short incubation in hydroxyurea." [] synonym: "decreased vegetative cell population growth after acute hydroxyurea treatment" EXACT [] xref: PMID:37200372 is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0002683 ! increased sensitivity to chemical property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-10T09:12:12Z" xsd:dateTime [Term] id: FYPO:0009110 name: normal vegetative cell population growth after short incubation in hydroxyurea def: "A cell growth phenotype in which cell population growth is normal after short incubation in hydroxyurea." [] synonym: "normal vegetative cell population growth after acute hydroxyurea treatment" EXACT [] xref: PMID:37200372 is_a: FYPO:0001357 ! normal vegetative cell population growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-10T09:26:07Z" xsd:dateTime [Term] id: FYPO:0009111 name: increased flocculation during vegetative growth def: "A vegetative cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells." [PMID:35924983] is_a: FYPO:0000155 ! increased flocculation property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-28T07:40:58Z" xsd:dateTime [Term] id: FYPO:0009112 name: abolished flocculation during vegetative growth def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which flocculation does not occur in conditions where wild-type cells floculate. Flocculation is the non-sexual aggregation of cells." [PMID:35924983] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-28T07:46:49Z" xsd:dateTime [Term] id: FYPO:0009113 name: abolished protein localization to mitotic spindle polar microtubules during anaphase B def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle polar microtubules during anaphase B does not occur." [PMID:34080538] synonym: "abolished protein localisation to interpolar microtubules during mitotic anaphase B" EXACT [] synonym: "abolished protein localisation to mitotic spindle polar microtubules during anaphase B" EXACT [] synonym: "abolished protein localization to interpolar microtubules during mitotic anaphase B" EXACT [] is_a: FYPO:0004754 ! abolished protein localization to mitotic spindle during mitosis property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-28T08:09:39Z" xsd:dateTime [Term] id: FYPO:0009114 name: transient monopolar mitotic spindle def: "A physical cellular phenotype in which the mitotic spindle remains monopolar when formed, with microtubules emanating from only one pole, for longer than wild-type, but eventually reaches bipolarity." [PMID:25057016] synonym: "monopolar mitotic spindle that eventually reaches bipolarity" EXACT [] synonym: "temporary monopolar mitotic spindle" EXACT [] is_a: FYPO:0000276 ! monopolar mitotic spindle property_value: http://purl.org/dc/elements/1.1/creator "PomBase:mlr" xsd:string property_value: http://purl.org/dc/elements/1.1/date "2023-07-28T08:20:20Z" xsd:dateTime [Typedef] id: during name: during xref: GOREL:0000002 property_value: usage "Identifies a process, cell cycle stage or life stage during which a phenotype is observed or relevant." xsd:string [Typedef] id: exists_during name: exists_during xref: GOREL:0000032 property_value: usage "Identifies a process, cell cycle stage or life stage during which a phenotype that affects a continuant, such as a cellular component or the level of a substance, is observed or relevant." xsd:string [Typedef] id: happens_during name: happens_during xref: GOREL:0000001 property_value: usage "Identifies a process, cell cycle stage or life stage during which a phenotype that affects an occurrent, i.e. a biological process or molecular function, is observed or relevant." xsd:string [Typedef] id: has_output name: has_output def: "p has output c if either: p has direct output c or p has output input c. Implies that if p happens, c always ensues." [GOC:curators] property_value: usage "Def comes from gorel file. Used in FYPO where one phenotype (p) always results in an additional phenotype (c) as a consequence. There may be other ways to get phenotype (c)." xsd:string [Typedef] id: has_part name: has_part xref: BFO:0000051 property_value: usage "Used in FYPO to link phenotypes that are collections of features to phenotypes representing the features." xsd:string is_transitive: true [Typedef] id: inheres_in name: inheres_in xref: RO:0000052 property_value: usage "Used in FYPO as described in PATO best practices; identifies an entity that displays a quality in an entity-quality logical definition. Used only in logical definitions (aka xps)." xsd:string [Typedef] id: inheres_in_part_of name: inheres in part of xref: RO:0002314 property_value: usage "Used in FYPO as described in MP/HP logical definition best practices for processes, and in an analogous manner for cell/cell part structure; identifies an entity that displays a quality in an entity-quality logical definition. Used only in logical definitions (aka xps)." xsd:string [Typedef] id: located_in name: located in xref: RO:0001025 property_value: usage "Used in FYPO to indicate where a physical quality phenotype is observed." xsd:string [Typedef] id: occurs_at name: occurs_at xref: GOREL:0000501 property_value: usage "This relation is not constrained with respect to whether the place where an event occurs completely surrounds, or is adjacent to, the location indicated. Example: chromatin silencing at centromere unfolds_around centromere : Repression of transcription of centromeric DNA by the formation of heterochromatin. Used in FYPO to identify a position where a phenotype is observed or relevant, usually a DNA or RNA sequence feature specified by a SO ID." xsd:string [Typedef] id: occurs_in name: occurs in xref: BFO:0000066 property_value: usage "Used in FYPO to identify a location, usually a cellular component or cell type, within which a phenotype is observed or relevant." xsd:string [Typedef] id: output_of name: output_of synonym: "formation results from" EXACT [PomBase:mah] property_value: usage "Inverse of has_output. Relation between a structure and a process that forms it, or between one process and a preceding process; A output_of B used where B has_output A isn't always true. Implies that process B is the only way to get output. Used in FYPO where one phenotype (c) always results when another phenotype (p) is present. Phenotype (p) may have other consequences in addition to phenotype (c)." xsd:string [Typedef] id: part_of name: part_of xref: BFO:0000050 property_value: usage "Used in FYPO to identify phenotypes that are always observed in the context of another, usually larger-scale, phenotype." xsd:string [Typedef] id: preceded_by name: preceded_by property_value: usage "Used in FYPO when a phenotype is observed after another event, usually a GO biological process, has ended, and where there isn't a suitable process to use with a during relation." xsd:string [Typedef] id: precedes name: precedes property_value: usage "Used in FYPO when a phenotype is observed before another event, usually a GO biological process, begins, and where there isn't a suitable process to use with a during relation." xsd:string [Typedef] id: qualifier name: qualifier xref: RO:0002573 property_value: usage "Used in FYPO as described in PATO best practices; placeholder relation to indicate normality/abnormality." xsd:string [Typedef] id: towards name: towards xref: RO:0002503 property_value: usage "Relation binding a relational quality or disposition to the relevant type of entity. Used in FYPO as described in PATO best practices; identifies abolished GO processes; identifies substances affected by phenotypes." xsd:string