id: gomodel:6690711d00000331
title: iron-sulfur cluster assembly (GO:0016226) and iron-sulfur cluster export from
  the mitochondrion  (GO:0140466)
taxon: NCBITaxon:4896
status: production
comments:
- 'Automated change 2025-02-13: GO:0106035 replaced by GO:0051604'
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      - http://www.pombase.org
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        - http://www.pombase.org
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    - term: ECO:0000501
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      - http://www.pombase.org
    term: GO:0005829
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    - term: ECO:0000266
      reference: PMID:26099175
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      - SGD:S000006252
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    term: GO:0044572
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    term: PomBase:SPCC1183.03c
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    - term: ECO:0000250
      reference: GO_REF:0000024
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      - http://www.pombase.org
    term: GO:0005759
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    - term: ECO:0000305
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      - http://www.pombase.org
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      reference: 'PMID: 26099175'
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      - http://www.pombase.org
    predicate: RO:0002304
    downstream_activity: gomodel:6690711d00000331/6690711d00000332
- id: gomodel:6690711d00000331/6690711d00000407
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    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000478264
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      - http://www.pombase.org
    term: PomBase:SPBC3B9.19
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      - http://www.pombase.org
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    evidence:
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      reference: PMID:12756240
      with_objects:
      - SGD:S000002784
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    term: GO:0044571
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      reference: GO_REF:0000002
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objects:
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  label: cysteine desulfurase activity
  type: gocam:Object
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  label: nfs1 Spom
  type: gocam:Object
- id: GO:0044571
  label: '[2Fe-2S] cluster assembly'
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: GO:0003674
  label: molecular_function
  type: gocam:Object
- id: PomBase:SPBC13G1.06c
  label: isd11 Spom
  type: gocam:Object
- id: ECO:0000307
  label: no evidence data found used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC4H3.09
  label: SPAC4H3.09 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0016651
  label: oxidoreductase activity, acting on NAD(P)H
  type: gocam:Object
- id: PomBase:SPAC22E12.10c
  label: etp1 Spom
  type: gocam:Object
- id: GO:0004324
  label: ferredoxin-NADP+ reductase activity
  type: gocam:Object
- id: PomBase:SPBC3B8.01c
  label: arh1 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPCC1183.03c
  label: fxn1 Spom
  type: gocam:Object
- id: GO:0140132
  label: iron-sulfur cluster chaperone activity
  type: gocam:Object
- id: PomBase:SPAC227.13c
  label: isu1 Spom
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: GO:0140662
  label: ATP-dependent protein folding chaperone
  type: gocam:Object
- id: PomBase:SPAC664.11
  label: ssc1 Spom
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: GO:0001671
  label: ATPase activator activity
  type: gocam:Object
- id: PomBase:SPAC144.08
  label: jac1 Spom
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0000774
  label: adenyl-nucleotide exchange factor activity
  type: gocam:Object
- id: PomBase:SPBC3B9.19
  label: mge1 Spom
  type: gocam:Object
- id: GO:0051537
  label: 2 iron, 2 sulfur cluster binding
  type: gocam:Object
- id: PomBase:SPAPB2B4.02
  label: grx5 Spom
  type: gocam:Object
- id: GO:0044572
  label: '[4Fe-4S] cluster assembly'
  type: gocam:Object
- id: GO:0140481
  label: ABC-type iron-sulfur cluster transporter activity
  type: gocam:Object
- id: PomBase:SPAC15A10.01
  label: atm1 Spom
  type: gocam:Object
- id: GO:0140466
  label: iron-sulfur cluster export from the mitochondrion
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: GO:0003958
  label: NADPH-hemoprotein reductase activity
  type: gocam:Object
- id: PomBase:SPAC1296.06
  label: tah18 Spom
  type: gocam:Object
- id: GO:0009055
  label: electron transfer activity
  type: gocam:Object
- id: PomBase:SPBC337.10c
  label: dre2 Spom
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0016226
  label: iron-sulfur cluster assembly
  type: gocam:Object
- id: CHEBI:35235
  label: L-cysteine zwitterion
  type: gocam:Object
- id: CHEBI:57972
  label: L-alanine zwitterion
  type: gocam:Object
- id: CHEBI:29033
  label: iron(2+)
  type: gocam:Object
- id: GO:0015093
  label: ferrous iron transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPAC8C9.12c
  label: mrs3 Spom
  type: gocam:Object
- id: GO:0048250
  label: iron import into the mitochondrion
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: GO:0005381
  label: iron ion transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPAC4G8.08
  label: mrs4 Spom
  type: gocam:Object
- id: GO:0140663
  label: ATP-dependent FeS chaperone activity
  type: gocam:Object
- id: GO:1904564
  label: cytosolic [4Fe-4S] assembly scaffold complex
  type: gocam:Object
- id: PomBase:SPAC637.08
  label: nbp35 Spom
  type: gocam:Object
- id: PomBase:SPAC806.02c
  label: SPAC806.02c Spom
  type: gocam:Object
- id: CHEBI:49601
  label: Fe2S2 iron-sulfur cluster
  type: gocam:Object
- id: CHEBI:64607
  label: Fe4S4 iron-sulfur cluster
  type: gocam:Object
- id: GO:0036455
  label: iron-sulfur transferase activity
  type: gocam:Object
- id: GO:0097361
  label: cytosolic [4Fe-4S] assembly targeting complex
  type: gocam:Object
- id: PomBase:SPCC1450.10c
  label: nar1 Spom
  type: gocam:Object
- id: PomBase:SPAC1071.02
  label: mms19 Spom
  type: gocam:Object
- id: ECO:0007631
  label: computational inference used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC144.16
  label: cia2 Spom
  type: gocam:Object
- id: CHEBI:35135
  label: iron-sulfur protein
  type: gocam:Object
- id: GO:0051604
  label: protein maturation
  type: gocam:Object
- id: GO:0120510
  label: mitochondrial [4Fe-4S] assembly complex
  type: gocam:Object
- id: PomBase:SPCC645.03c
  label: isa1 Spom
  type: gocam:Object
- id: PomBase:SPBC3B9.17
  label: isa2 Spom
  type: gocam:Object
- id: PomBase:SPAC21E11.07
  label: iba57 Spom
  type: gocam:Object
- id: PomBase:SPBC1709.19c
  label: nfu1 Spom
  type: gocam:Object
- id: PomBase:SPCC4B3.11c
  label: fra3 Spom
  type: gocam:Object
- id: PomBase:SPBC16E9.06c
  label: uvi31 Spom
  type: gocam:Object
- id: GO:0003951
  label: NAD+ kinase activity
  type: gocam:Object
- id: PomBase:SPAC323.01c
  label: pos5 Spom
  type: gocam:Object
- id: GO:0006741
  label: NADP+ biosynthetic process
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2025-07-16'
  provided_by:
  - http://www.pombase.org